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Table of Contents

October 25, 2011; vol. 108 no. 43

This Week in PNAS

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    In This Issue
    PNAS October 25, 2011 108 (43) 17571-17572; https://doi.org/10.1073/iti4311108

Letters (Online Only)

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    Methane contamination of drinking water caused by hydraulic fracturing remains unproven
    Richard J. Davies
    PNAS October 25, 2011 108 (43) E871; https://doi.org/10.1073/pnas.1113299108
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    Reply to Davies: Hydraulic fracturing remains a possible mechanism for observed methane contamination of drinking water
    Robert B. Jackson, Stephen G. Osborn, Avner Vengosh, and Nathaniel R. Warner
    PNAS October 25, 2011 108 (43) E872; https://doi.org/10.1073/pnas.1113768108
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    Reply to Sharp et al.: Host species sampling bias and Plasmodium falciparum origin paradigm shifts
    Franck Prugnolle, Patrick Durand, Benjamin Ollomo, Francisco J. Ayala, and François Renaud
    PNAS October 25, 2011 108 (43) E873; https://doi.org/10.1073/pnas.1112821108

Commentary

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    To intercalate or semiintercalate, or both?
    Claudia Turro
    PNAS October 25, 2011 108 (43) 17573-17574; https://doi.org/10.1073/pnas.1114519108

    See companion article:

    • Structure determination of an intercalating ruthenium dipyridophenazine complex which kinks DNA by semiintercalation of a tetraazaphenanthrene ligand
      - Oct 03, 2011

PNAS Plus (Author Summaries and Research Articles)

  • Social Sciences – Sustainability Science – Biological Sciences – Ecology

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      Identifying critical regions in small-world marine metapopulations
      James R. Watson, David A. Siegel, Bruce E. Kendall, Satoshi Mitarai, Andrew Rassweiller, and Steven D. Gaines
      PNAS October 25, 2011 108 (43) E907-E913; https://doi.org/10.1073/pnas.1111461108
  • Biological Sciences

    • Applied Biological Sciences

      • Open Access
        Requirements for effective malaria control with homing endonuclease genes
        Anne Deredec, H. Charles J. Godfray, and Austin Burt
        PNAS October 25, 2011 108 (43) E874-E880; https://doi.org/10.1073/pnas.1110717108
    • Biochemistry

      • You have access
        Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain
        Michael B. Winter, Mark A. Herzik Jr., John Kuriyan, and Michael A. Marletta
        PNAS October 25, 2011 108 (43) E881-E889; https://doi.org/10.1073/pnas.1114038108
    • Biophysics and Computational Biology

      • You have access
        Locating an extracellular K+-dependent interaction site that modulates betaine-binding of the Na+-coupled betaine symporter BetP
        Lin Ge, Camilo Perez, Izabela Waclawska, Christine Ziegler, and Daniel J. Muller
        PNAS October 25, 2011 108 (43) E890-E898; https://doi.org/10.1073/pnas.1109597108
    • Cell Biology

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        Cardiac myocyte follistatin-like 1 functions to attenuate hypertrophy following pressure overload
        Masayuki Shimano, Noriyuki Ouchi, Kazuto Nakamura, Bram van Wijk, Koji Ohashi, Yasuhide Asaumi, Akiko Higuchi, David R. Pimentel, Flora Sam, Toyoaki Murohara, Maurice J. B. van den Hoff, and Kenneth Walsh
        PNAS October 25, 2011 108 (43) E899-E906; https://doi.org/10.1073/pnas.1108559108
    • Genetics

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        Independent modulation of the kinase and polo-box activities of Cdc5 protein unravels unique roles in the maintenance of genome stability
        Hery Ratsima, Anne-Marie Ladouceur, Mirela Pascariu, Véronique Sauvé, Zeina Salloum, Paul S. Maddox, and Damien D'Amours
        PNAS October 25, 2011 108 (43) E914-E923; https://doi.org/10.1073/pnas.1106448108
      • You have access
        Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF
        Erez Feige, Satoru Yokoyama, Carmit Levy, Mehdi Khaled, Vivien Igras, Richard J. Lin, Stephen Lee, Hans R. Widlund, Scott R. Granter, Andrew L. Kung, and David E. Fisher
        PNAS October 25, 2011 108 (43) E924-E933; https://doi.org/10.1073/pnas.1106351108
    • Immunology

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        Requirement for complement in antibody responses is not explained by the classic pathway activator IgM
        Christian Rutemark, Elisabeth Alicot, Anna Bergman, Minghe Ma, Andrew Getahun, Stephan Ellmerich, Michael C. Carroll, and Birgitta Heyman
        PNAS October 25, 2011 108 (43) E934-E942; https://doi.org/10.1073/pnas.1109831108
    • Medical Sciences

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        A whole-genome RNAi screen identifies an 8q22 gene cluster that inhibits death receptor-mediated apoptosis
        Nicholas Dompe, Celina Sanchez Rivers, Li Li, Shaun Cordes, Martin Schwickart, Elizabeth A. Punnoose, Lukas Amler, Somasekar Seshagiri, Jerry Tang, Zora Modrusan, and David P. Davis
        PNAS October 25, 2011 108 (43) E943-E951; https://doi.org/10.1073/pnas.1100132108
    • Neuroscience

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        Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling
        Bogdan Beirowski, Jason Gustin, Sean M. Armour, Hiroyasu Yamamoto, Andreu Viader, Brian J. North, Shaday Michán, Robert H. Baloh, Judy P. Golden, Robert E. Schmidt, David A. Sinclair, Johan Auwerx, and Jeffrey Milbrandt
        PNAS October 25, 2011 108 (43) E952-E961; https://doi.org/10.1073/pnas.1104969108
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        Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia
        • From the Cover
        Gregory C. Carlson, Konrad Talbot, Tobias B. Halene, Michael J. Gandal, Hala A. Kazi, Laura Schlosser, Quan H. Phung, Raquel E. Gur, Steven E. Arnold, and Steven J. Siegel
        PNAS October 25, 2011 108 (43) E962-E970; https://doi.org/10.1073/pnas.1109625108

Retrospective

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    Edward (Ted) G. Jones, a neuroscientist and prolific neuroanatomist
    William E. Bunney
    PNAS October 25, 2011 108 (43) 17597; https://doi.org/10.1073/pnas.1112285108

Physical Sciences

  • Applied Physical Sciences

    • Open Access
      Compact and flexible raster scanning multiphoton endoscope capable of imaging unstained tissue
      David R. Rivera, Christopher M. Brown, Dimitre G. Ouzounov, Ina Pavlova, Demirhan Kobat, Watt W. Webb, and Chris Xu
      PNAS October 25, 2011 108 (43) 17598-17603; https://doi.org/10.1073/pnas.1114746108
  • Astronomy

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      Fast accretion of the Earth with a late Moon-forming giant impact
      Gang Yu and Stein B. Jacobsen
      PNAS October 25, 2011 108 (43) 17604-17609; https://doi.org/10.1073/pnas.1108544108
  • Chemistry

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      Structure determination of an intercalating ruthenium dipyridophenazine complex which kinks DNA by semiintercalation of a tetraazaphenanthrene ligand
      • From the Cover
      James P. Hall, Kyra O’Sullivan, Abeer Naseer, Jayden A. Smith, John M. Kelly, and Christine J. Cardin
      PNAS October 25, 2011 108 (43) 17610-17614; https://doi.org/10.1073/pnas.1108685108

      See companion article:

      • To intercalate or semiintercalate, or both?
        - Oct 13, 2011
    • You have access
      Quantum state and process tomography of energy transfer systems via ultrafast spectroscopy
      Joel Yuen-Zhou, Jacob J. Krich, Masoud Mohseni, and Alán Aspuru-Guzik
      PNAS October 25, 2011 108 (43) 17615-17620; https://doi.org/10.1073/pnas.1110642108
    • You have access
      Extended surfaces modulate hydrophobic interactions of neighboring solutes
      Amish J. Patel, Patrick Varilly, Sumanth N. Jamadagni, Hari Acharya, Shekhar Garde, and David Chandler
      PNAS October 25, 2011 108 (43) 17678-17683; https://doi.org/10.1073/pnas.1110703108
  • Computer Sciences

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      Comparing machines and humans on a visual categorization test
      François Fleuret, Ting Li, Charles Dubout, Emma K. Wampler, Steven Yantis, and Donald Geman
      PNAS October 25, 2011 108 (43) 17621-17625; https://doi.org/10.1073/pnas.1109168108
  • Environmental Sciences

    • Open Access
      Temporal clustering of tropical cyclones and its ecosystem impacts
      Peter J. Mumby, Renato Vitolo, and David B. Stephenson
      PNAS October 25, 2011 108 (43) 17626-17630; https://doi.org/10.1073/pnas.1100436108
  • Geology

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      Rapid expansion of oceanic anoxia immediately before the end-Permian mass extinction
      • From the Cover
      Gregory A. Brennecka, Achim D. Herrmann, Thomas J. Algeo, and Ariel D. Anbar
      PNAS October 25, 2011 108 (43) 17631-17634; https://doi.org/10.1073/pnas.1106039108
  • Geophysics

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      Evidence of magnetic isotope effects during thermochemical sulfate reduction
      Harry Oduro, Brian Harms, Herman O. Sintim, Alan J. Kaufman, George Cody, and James Farquhar
      PNAS October 25, 2011 108 (43) 17635-17638; https://doi.org/10.1073/pnas.1108112108
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      Early Archean serpentine mud volcanoes at Isua, Greenland, as a niche for early life
      Marie-Laure Pons, Ghylaine Quitté, Toshiyuki Fujii, Minik T. Rosing, Bruno Reynard, Frederic Moynier, Chantal Douchet, and Francis Albarède
      PNAS October 25, 2011 108 (43) 17639-17643; https://doi.org/10.1073/pnas.1108061108

Social Sciences

  • Sustainability Science

    • You have access
      Identifying critical regions in small-world marine metapopulations
      James R. Watson, David A. Siegel, Bruce E. Kendall, Satoshi Mitarai, Andrew Rassweiller, and Steven D. Gaines
      PNAS October 25, 2011 108 (43) E907-E913; https://doi.org/10.1073/pnas.1111461108

Biological Sciences

  • Applied Biological Sciences

    • Open Access
      Requirements for effective malaria control with homing endonuclease genes
      Anne Deredec, H. Charles J. Godfray, and Austin Burt
      PNAS October 25, 2011 108 (43) E874-E880; https://doi.org/10.1073/pnas.1110717108
  • Biochemistry

    • You have access
      Tunnels modulate ligand flux in a heme nitric oxide/oxygen binding (H-NOX) domain
      Michael B. Winter, Mark A. Herzik Jr., John Kuriyan, and Michael A. Marletta
      PNAS October 25, 2011 108 (43) E881-E889; https://doi.org/10.1073/pnas.1114038108
    • You have access
      Structure determination of an intercalating ruthenium dipyridophenazine complex which kinks DNA by semiintercalation of a tetraazaphenanthrene ligand
      • From the Cover
      James P. Hall, Kyra O’Sullivan, Abeer Naseer, Jayden A. Smith, John M. Kelly, and Christine J. Cardin
      PNAS October 25, 2011 108 (43) 17610-17614; https://doi.org/10.1073/pnas.1108685108

      See companion article:

      • To intercalate or semiintercalate, or both?
        - Oct 13, 2011
    • You have access
      Structural evidence for the rare tautomer hypothesis of spontaneous mutagenesis
      Weina Wang, Homme W. Hellinga, and Lorena S. Beese
      PNAS October 25, 2011 108 (43) 17644-17648; https://doi.org/10.1073/pnas.1114496108
    • You have access
      Complete set of glycosyltransferase structures in the calicheamicin biosynthetic pathway reveals the origin of regiospecificity
      Aram Chang, Shanteri Singh, Kate E. Helmich, Randal D. Goff, Craig A. Bingman, Jon S. Thorson, and George N. Phillips Jr.
      PNAS October 25, 2011 108 (43) 17649-17654; https://doi.org/10.1073/pnas.1108484108
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      Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways
      Luke J. Drury, Joshua J. Ziarek, Stéphanie Gravel, Christopher T. Veldkamp, Tomonori Takekoshi, Samuel T. Hwang, Nikolaus Heveker, Brian F. Volkman, and Michael B. Dwinell
      PNAS October 25, 2011 108 (43) 17655-17660; https://doi.org/10.1073/pnas.1101133108
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      Entrance of the proton pathway in cbb3-type heme-copper oxidases
      Hyun Ju Lee, Robert B. Gennis, and Pia Ädelroth
      PNAS October 25, 2011 108 (43) 17661-17666; https://doi.org/10.1073/pnas.1107543108
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      Cap-snatching mechanism in yeast L-A double-stranded RNA virus
      Tsutomu Fujimura and Rosa Esteban
      PNAS October 25, 2011 108 (43) 17667-17671; https://doi.org/10.1073/pnas.1111900108
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      Solution X-ray scattering combined with computational modeling reveals multiple conformations of covalently bound ubiquitin on PCNA
      Susan E. Tsutakawa, Adam W. Van Wynsberghe, Bret D. Freudenthal, Christopher P. Weinacht, Lokesh Gakhar, M. Todd Washington, Zhihao Zhuang, John A. Tainer, and Ivaylo Ivanov
      PNAS October 25, 2011 108 (43) 17672-17677; https://doi.org/10.1073/pnas.1110480108
  • Biophysics and Computational Biology

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      Locating an extracellular K+-dependent interaction site that modulates betaine-binding of the Na+-coupled betaine symporter BetP
      Lin Ge, Camilo Perez, Izabela Waclawska, Christine Ziegler, and Daniel J. Muller
      PNAS October 25, 2011 108 (43) E890-E898; https://doi.org/10.1073/pnas.1109597108
    • You have access
      Quantum state and process tomography of energy transfer systems via ultrafast spectroscopy
      Joel Yuen-Zhou, Jacob J. Krich, Masoud Mohseni, and Alán Aspuru-Guzik
      PNAS October 25, 2011 108 (43) 17615-17620; https://doi.org/10.1073/pnas.1110642108
    • You have access
      Extended surfaces modulate hydrophobic interactions of neighboring solutes
      Amish J. Patel, Patrick Varilly, Sumanth N. Jamadagni, Hari Acharya, Shekhar Garde, and David Chandler
      PNAS October 25, 2011 108 (43) 17678-17683; https://doi.org/10.1073/pnas.1110703108
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      Structure and function of multiple Ca2+-binding sites in a K+ channel regulator of K+ conductance (RCK) domain
      Victor P. T. Pau, Frank J. Smith, Alexander B. Taylor, Liubov V. Parfenova, Elsie Samakai, Matthew M. Callaghan, Karin Abarca-Heidemann, P. John Hart, and Brad S. Rothberg
      PNAS October 25, 2011 108 (43) 17684-17689; https://doi.org/10.1073/pnas.1107229108
  • Cell Biology

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      Cardiac myocyte follistatin-like 1 functions to attenuate hypertrophy following pressure overload
      Masayuki Shimano, Noriyuki Ouchi, Kazuto Nakamura, Bram van Wijk, Koji Ohashi, Yasuhide Asaumi, Akiko Higuchi, David R. Pimentel, Flora Sam, Toyoaki Murohara, Maurice J. B. van den Hoff, and Kenneth Walsh
      PNAS October 25, 2011 108 (43) E899-E906; https://doi.org/10.1073/pnas.1108559108
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      Involvement of O-glycosylation defining oncofetal fibronectin in epithelial-mesenchymal transition process
      Leonardo Freire-de-Lima, Kirill Gelfenbeyn, Yao Ding, Ulla Mandel, Henrik Clausen, Kazuko Handa, and Sen-itiroh Hakomori
      PNAS October 25, 2011 108 (43) 17690-17695; https://doi.org/10.1073/pnas.1115191108
  • Developmental Biology

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      Quiescent gastric stem cells maintain the adult Drosophila stomach
      Marie Strand and Craig A. Micchelli
      PNAS October 25, 2011 108 (43) 17696-17701; https://doi.org/10.1073/pnas.1109794108
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      Suzanne A. Hartford, Yunhai Luo, Teresa L. Southard, Irene M. Min, John T. Lis, and John C. Schimenti
      PNAS October 25, 2011 108 (43) 17702-17707; https://doi.org/10.1073/pnas.1113524108
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      Inverted selective plane illumination microscopy (iSPIM) enables coupled cell identity lineaging and neurodevelopmental imaging in Caenorhabditis elegans
      Yicong Wu, Alireza Ghitani, Ryan Christensen, Anthony Santella, Zhuo Du, Gary Rondeau, Zhirong Bao, Daniel Colón-Ramos, and Hari Shroff
      PNAS October 25, 2011 108 (43) 17708-17713; https://doi.org/10.1073/pnas.1108494108
  • Ecology

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      Identifying critical regions in small-world marine metapopulations
      James R. Watson, David A. Siegel, Bruce E. Kendall, Satoshi Mitarai, Andrew Rassweiller, and Steven D. Gaines
      PNAS October 25, 2011 108 (43) E907-E913; https://doi.org/10.1073/pnas.1111461108
    • Open Access
      Temporal clustering of tropical cyclones and its ecosystem impacts
      Peter J. Mumby, Renato Vitolo, and David B. Stephenson
      PNAS October 25, 2011 108 (43) 17626-17630; https://doi.org/10.1073/pnas.1100436108
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      Evidence of cellulose metabolism by the giant panda gut microbiome
      Lifeng Zhu, Qi Wu, Jiayin Dai, Shanning Zhang, and Fuwen Wei
      PNAS October 25, 2011 108 (43) 17714-17719; https://doi.org/10.1073/pnas.1017956108
    • You have access
      Molecular study of worldwide distribution and diversity of soil animals
      Tiehang Wu, Edward Ayres, Richard D. Bardgett, Diana H. Wall, and James R. Garey
      PNAS October 25, 2011 108 (43) 17720-17725; https://doi.org/10.1073/pnas.1103824108
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      Macroalgal terpenes function as allelopathic agents against reef corals
      Douglas B. Rasher, E. Paige Stout, Sebastian Engel, Julia Kubanek, and Mark E. Hay
      PNAS October 25, 2011 108 (43) 17726-17731; https://doi.org/10.1073/pnas.1108628108
  • Environmental Sciences

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      Effects of bisphenol A and triclocarban on brain-specific expression of aromatase in early zebrafish embryos
      Eunah Chung, Maria C. Genco, Laura Megrelis, and Joan V. Ruderman
      PNAS October 25, 2011 108 (43) 17732-17737; https://doi.org/10.1073/pnas.1115187108
  • Evolution

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      Ancient host specificity within a single species of brood parasitic bird
      • From the Cover
      Claire N. Spottiswoode, Katherine Faust Stryjewski, Suhel Quader, John F. R. Colebrook-Robjent, and Michael D. Sorenson
      PNAS October 25, 2011 108 (43) 17738-17742; https://doi.org/10.1073/pnas.1109630108

      See companion article:

      • Ladies and gentes: Maternally inherited DNA and ancient honeyguide host races
        - Oct 17, 2011
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      Sexual selection by female immunity against paternal antigens can fix loss of function alleles
      Darius Ghaderi, Stevan A. Springer, Fang Ma, Miriam Cohen, Patrick Secrest, Rachel E. Taylor, Ajit Varki, and Pascal Gagneux
      PNAS October 25, 2011 108 (43) 17743-17748; https://doi.org/10.1073/pnas.1102302108
  • Genetics

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      Independent modulation of the kinase and polo-box activities of Cdc5 protein unravels unique roles in the maintenance of genome stability
      Hery Ratsima, Anne-Marie Ladouceur, Mirela Pascariu, Véronique Sauvé, Zeina Salloum, Paul S. Maddox, and Damien D'Amours
      PNAS October 25, 2011 108 (43) E914-E923; https://doi.org/10.1073/pnas.1106448108
    • You have access
      Hypoxia-induced transcriptional repression of the melanoma-associated oncogene MITF
      Erez Feige, Satoru Yokoyama, Carmit Levy, Mehdi Khaled, Vivien Igras, Richard J. Lin, Stephen Lee, Hans R. Widlund, Scott R. Granter, Andrew L. Kung, and David E. Fisher
      PNAS October 25, 2011 108 (43) E924-E933; https://doi.org/10.1073/pnas.1106351108
  • Immunology

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      Requirement for complement in antibody responses is not explained by the classic pathway activator IgM
      Christian Rutemark, Elisabeth Alicot, Anna Bergman, Minghe Ma, Andrew Getahun, Stephan Ellmerich, Michael C. Carroll, and Birgitta Heyman
      PNAS October 25, 2011 108 (43) E934-E942; https://doi.org/10.1073/pnas.1109831108
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      A role for c-Myc in regulating anti-mycobacterial responses
      Howard C. H. Yim, James C. B. Li, John C. H. Pong, and Allan S. Y. Lau
      PNAS October 25, 2011 108 (43) 17749-17754; https://doi.org/10.1073/pnas.1104892108
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      A whole-genome RNAi screen identifies an 8q22 gene cluster that inhibits death receptor-mediated apoptosis
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      PNAS October 25, 2011 108 (43) E943-E951; https://doi.org/10.1073/pnas.1100132108
    • Open Access
      Loss-of-function mutations in Notch receptors in cutaneous and lung squamous cell carcinoma
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    • You have access
      Mutation of a single allele of the cancer susceptibility gene BRCA1 leads to genomic instability in human breast epithelial cells
      Hiroyuki Konishi, Morassa Mohseni, Akina Tamaki, Joseph P. Garay, Sarah Croessmann, Sivasundaram Karnan, Akinobu Ota, Hong Yuen Wong, Yuko Konishi, Bedri Karakas, Khola Tahir, Abde M. Abukhdeir, John P. Gustin, Justin Cidado, Grace M. Wang, David Cosgrove, Rory Cochran, Danijela Jelovac, Michaela J. Higgins, Sabrina Arena, Lauren Hawkins, Josh Lauring, Amy L. Gross, Christopher M. Heaphy, Yositaka Hosokawa, Edward Gabrielson, Alan K. Meeker, Kala Visvanathan, Pedram Argani, Kurtis E. Bachman, and Ben Ho Park
      PNAS October 25, 2011 108 (43) 17773-17778; https://doi.org/10.1073/pnas.1110969108
    • Open Access
      Antitumorigenic potential of STAT3 alternative splicing modulation
      Francesca Zammarchi, Elisa de Stanchina, Eirini Bournazou, Teerawit Supakorndej, Kathryn Martires, Elyn Riedel, Adriana D. Corben, Jacqueline F. Bromberg, and Luca Cartegni
      PNAS October 25, 2011 108 (43) 17779-17784; https://doi.org/10.1073/pnas.1108482108
  • Microbiology

    • Open Access
      Transcriptional and functional analysis of galactooligosaccharide uptake by lacS in Lactobacillus acidophilus
      Joakim M. Andersen, Rodolphe Barrangou, Maher Abou Hachem, Sampo Lahtinen, Yong Jun Goh, Birte Svensson, and Todd R. Klaenhammer
      PNAS October 25, 2011 108 (43) 17785-17790; https://doi.org/10.1073/pnas.1114152108
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      Bacterial flavin-containing monooxygenase is trimethylamine monooxygenase
      Yin Chen, Nisha A. Patel, Andrew Crombie, James H. Scrivens, and J. Colin Murrell
      PNAS October 25, 2011 108 (43) 17791-17796; https://doi.org/10.1073/pnas.1112928108
  • Neuroscience

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      Sir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signaling
      Bogdan Beirowski, Jason Gustin, Sean M. Armour, Hiroyasu Yamamoto, Andreu Viader, Brian J. North, Shaday Michán, Robert H. Baloh, Judy P. Golden, Robert E. Schmidt, David A. Sinclair, Johan Auwerx, and Jeffrey Milbrandt
      PNAS October 25, 2011 108 (43) E952-E961; https://doi.org/10.1073/pnas.1104969108
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      Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia
      • From the Cover
      Gregory C. Carlson, Konrad Talbot, Tobias B. Halene, Michael J. Gandal, Hala A. Kazi, Laura Schlosser, Quan H. Phung, Raquel E. Gur, Steven E. Arnold, and Steven J. Siegel
      PNAS October 25, 2011 108 (43) E962-E970; https://doi.org/10.1073/pnas.1109625108
    • Open Access
      A soluble α-synuclein construct forms a dynamic tetramer
      Wei Wang, Iva Perovic, Johnathan Chittuluru, Alice Kaganovich, Linh T. T. Nguyen, Jingling Liao, Jared R. Auclair, Derrick Johnson, Anuradha Landeru, Alana K. Simorellis, Shulin Ju, Mark R. Cookson, Francisco J. Asturias, Jeffrey N. Agar, Brian N. Webb, ChulHee Kang, Dagmar Ringe, Gregory A. Petsko, Thomas C. Pochapsky, and Quyen Q. Hoang
      PNAS October 25, 2011 108 (43) 17797-17802; https://doi.org/10.1073/pnas.1113260108
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      Astrocytes carrying the superoxide dismutase 1 (SOD1G93A) mutation induce wild-type motor neuron degeneration in vivo
      Sophia T. Papadeas, Sarah E. Kraig, Colin O'Banion, Angelo C. Lepore, and Nicholas J. Maragakis
      PNAS October 25, 2011 108 (43) 17803-17808; https://doi.org/10.1073/pnas.1103141108
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      New methods devised specify the size and color of the spots monkeys see when striate cortex (area V1) is electrically stimulated
      • From the Cover
      Peter H. Schiller, Warren M. Slocum, Michelle C. Kwak, Geoffrey L. Kendall, and Edward J. Tehovnik
      PNAS October 25, 2011 108 (43) 17809-17814; https://doi.org/10.1073/pnas.1108337108
    • Open Access
      Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood–brain water uptake and confers barrier function on perivascular astrocyte endfeet
      Nadia Nabil Haj-Yasein, Gry Fluge Vindedal, Martine Eilert-Olsen, Georg Andreas Gundersen, Øivind Skare, Petter Laake, Arne Klungland, Anna Elisabeth Thorén, John Michael Burkhardt, Ole Petter Ottersen, and Erlend Arnulf Nagelhus
      PNAS October 25, 2011 108 (43) 17815-17820; https://doi.org/10.1073/pnas.1110655108
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      Active opsin loci adopt intrachromosomal loops that depend on the photoreceptor transcription factor network
      Guang-Hua Peng and Shiming Chen
      PNAS October 25, 2011 108 (43) 17821-17826; https://doi.org/10.1073/pnas.1109209108
    • You have access
      Oxygen modulation of neurovascular coupling in the retina
      Anusha Mishra, Arif Hamid, and Eric A. Newman
      PNAS October 25, 2011 108 (43) 17827-17831; https://doi.org/10.1073/pnas.1110533108
  • Physiology

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      Subunit stoichiometry of human Orai1 and Orai3 channels in closed and open states
      Angelo Demuro, Aubin Penna, Olga Safrina, Andriy V. Yeromin, Anna Amcheslavsky, Michael D. Cahalan, and Ian Parker
      PNAS October 25, 2011 108 (43) 17832-17837; https://doi.org/10.1073/pnas.1114814108
    • You have access
      Mutations in Orai1 transmembrane segment 1 cause STIM1-independent activation of Orai1 channels at glycine 98 and channel closure at arginine 91
      Shenyuan L. Zhang, Andriy V. Yeromin, Junjie Hu, Anna Amcheslavsky, Hongying Zheng, and Michael D. Cahalan
      PNAS October 25, 2011 108 (43) 17838-17843; https://doi.org/10.1073/pnas.1114821108
  • Plant Biology

    • Open Access
      Phosphorylation of a mitotic kinesin-like protein and a MAPKKK by cyclin-dependent kinases (CDKs) is involved in the transition to cytokinesis in plants
      Michiko Sasabe, Véronique Boudolf, Lieven De Veylder, Dirk Inzé, Pascal Genschik, and Yasunori Machida
      PNAS October 25, 2011 108 (43) 17844-17849; https://doi.org/10.1073/pnas.1110174108
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      Clusters of bioactive compounds target dynamic endomembrane networks in vivo
      Georgia Drakakaki, Stéphanie Robert, Anna-Maria Szatmari, Michelle Q. Brown, Shingo Nagawa, Daniel Van Damme, Marilyn Leonard, Zhenbiao Yang, Thomas Girke, Sandra L. Schmid, Eugenia Russinova, Jiří Friml, Natasha V. Raikhel, and Glenn R. Hicks
      PNAS October 25, 2011 108 (43) 17850-17855; https://doi.org/10.1073/pnas.1108581108
  • Psychological and Cognitive Sciences

    • You have access
      Comparing machines and humans on a visual categorization test
      François Fleuret, Ting Li, Charles Dubout, Emma K. Wampler, Steven Yantis, and Donald Geman
      PNAS October 25, 2011 108 (43) 17621-17625; https://doi.org/10.1073/pnas.1109168108

Corrections

  • You have access
    Correction for Hoffman et al., Nurture affects gender differences in spatial abilities
    PNAS October 25, 2011 108 (43) 17856; https://doi.org/10.1073/pnas.1115576108
  • You have access
    Correction for Cheong et al., Ammonia-induced autophagy is independent of ULK1/ULK2 kinases
    PNAS October 25, 2011 108 (43) 17856; https://doi.org/10.1073/pnas.1115120108
  • You have access
    Correction for Nissan et al., Functional melanocytes derived from human pluripotent stem cells engraft into pluristratified epidermis
    PNAS October 25, 2011 108 (43) 17856; https://doi.org/10.1073/pnas.1115035108
  • You have access
    Correction for O’Connor et al., Minimization of the Legionella pneumophila genome reveals chromosomal regions involved in host range expansion
    PNAS October 25, 2011 108 (43) 17856; https://doi.org/10.1073/pnas.1115233108
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Proceedings of the National Academy of Sciences: 108 (43)
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