Skip to main content
  • Submit
  • About
    • Editorial Board
    • PNAS Staff
    • FAQ
    • Rights and Permissions
    • Site Map
  • Contact
  • Journal Club
  • Subscribe
    • Subscription Rates
    • Subscriptions FAQ
    • Open Access
    • Recommend PNAS to Your Librarian
  • Log in
  • My Cart

Main menu

  • Home
  • Articles
    • Current
    • Latest Articles
    • Special Features
    • Colloquia
    • Collected Articles
    • PNAS Classics
    • Archive
  • Front Matter
  • News
    • For the Press
    • Highlights from Latest Articles
    • PNAS in the News
  • Podcasts
  • Authors
    • Information for Authors
    • Purpose and Scope
    • Editorial and Journal Policies
    • Submission Procedures
    • For Reviewers
    • Author FAQ
  • Submit
  • About
    • Editorial Board
    • PNAS Staff
    • FAQ
    • Rights and Permissions
    • Site Map
  • Contact
  • Journal Club
  • Subscribe
    • Subscription Rates
    • Subscriptions FAQ
    • Open Access
    • Recommend PNAS to Your Librarian

User menu

  • Log in
  • My Cart

Search

  • Advanced search
Home
Home

Advanced Search

  • Home
  • Articles
    • Current
    • Latest Articles
    • Special Features
    • Colloquia
    • Collected Articles
    • PNAS Classics
    • Archive
  • Front Matter
  • News
    • For the Press
    • Highlights from Latest Articles
    • PNAS in the News
  • Podcasts
  • Authors
    • Information for Authors
    • Purpose and Scope
    • Editorial and Journal Policies
    • Submission Procedures
    • For Reviewers
    • Author FAQ

New Research In

Physical Sciences

Featured Portals

  • Physics
  • Chemistry
  • Sustainability Science

Articles by Topic

  • Applied Mathematics
  • Applied Physical Sciences
  • Astronomy
  • Computer Sciences
  • Earth, Atmospheric, and Planetary Sciences
  • Engineering
  • Environmental Sciences
  • Mathematics
  • Statistics

Social Sciences

Featured Portals

  • Anthropology
  • Sustainability Science

Articles by Topic

  • Economic Sciences
  • Environmental Sciences
  • Political Sciences
  • Psychological and Cognitive Sciences
  • Social Sciences

Biological Sciences

Featured Portals

  • Sustainability Science

Articles by Topic

  • Agricultural Sciences
  • Anthropology
  • Applied Biological Sciences
  • Biochemistry
  • Biophysics and Computational Biology
  • Cell Biology
  • Developmental Biology
  • Ecology
  • Environmental Sciences
  • Evolution
  • Genetics
  • Immunology and Inflammation
  • Medical Sciences
  • Microbiology
  • Neuroscience
  • Pharmacology
  • Physiology
  • Plant Biology
  • Population Biology
  • Psychological and Cognitive Sciences
  • Sustainability Science
  • Systems Biology

Table of Contents

May 22, 2012; vol. 109 no. 21

This Week in PNAS

  • You have access
    In This Issue
    PNAS May 22, 2012 109 (21) 7949-7950; https://doi.org/10.1073/iti2112109

Letters (Online Only)

  • You have access
    Cross-cultural experiments are more useful when explanans and explanandum are separated
    André van Hoorn
    PNAS May 22, 2012 109 (21) E1329; https://doi.org/10.1073/pnas.1202243109
  • You have access
    Degenerate Primer IDs and the Birthday Problem
    Daniel J. Sheward, Ben Murrell, and Carolyn Williamson
    PNAS May 22, 2012 109 (21) E1330; https://doi.org/10.1073/pnas.1203613109
  • You have access
    Reply to Sheward et al.: Two sampling issues in using Primer IDs
    Cassandra B. Jabara and Ronald Swanstrom
    PNAS May 22, 2012 109 (21) E1331; https://doi.org/10.1073/pnas.1204608109
  • You have access
    H5N1 influenza virus seroepidemiological studies: The facts revisited
    Michael T. Osterholm and Nicholas S. Kelley
    PNAS May 22, 2012 109 (21) E1332; https://doi.org/10.1073/pnas.1203949109
  • You have access
    Reply to Osterholm and Kelley: H5N1 in humans—the threat is not as bad as it may seem
    Peter Palese and Taia T. Wang
    PNAS May 22, 2012 109 (21) E1333; https://doi.org/10.1073/pnas.1204160109

Commentaries

  • You have access
    Controlling the shapes and assemblages of graphene
    Mauricio Terrones
    PNAS May 22, 2012 109 (21) 7951-7952; https://doi.org/10.1073/pnas.1205024109
  • You have access
    Apex predators and trophic cascades in large marine ecosystems: Learning from serendipity
    Robert S. Steneck
    PNAS May 22, 2012 109 (21) 7953-7954; https://doi.org/10.1073/pnas.1205591109
  • You have access
    Tumor suppressor p53 (TP53) at the crossroads of the exposome and the cancer genome
    Aaron J. Schetter and Curtis C. Harris
    PNAS May 22, 2012 109 (21) 7955-7956; https://doi.org/10.1073/pnas.1205457109

Physical Sciences

  • Applied Mathematics

    • You have access
      Moment-based inference predicts bimodality in transient gene expression
      Christoph Zechner, Jakob Ruess, Peter Krenn, Serge Pelet, Matthias Peter, John Lygeros, and Heinz Koeppl
      PNAS May 22, 2012 109 (21) 8340-8345; https://doi.org/10.1073/pnas.1200161109
  • Applied Physical Sciences

    • You have access
      Phantom tones and suppressive masking by active nonlinear oscillation of the hair-cell bundle
      Jérémie Barral and Pascal Martin
      PNAS May 22, 2012 109 (21) E1344-E1351; https://doi.org/10.1073/pnas.1202426109
    • Open Access
      Detecting activity-evoked pH changes in human brain
      Vincent A. Magnotta, Hye-Young Heo, Brian J. Dlouhy, Nader S. Dahdaleh, Robin L. Follmer, Daniel R. Thedens, Michael J. Welsh, and John A. Wemmie
      PNAS May 22, 2012 109 (21) 8270-8273; https://doi.org/10.1073/pnas.1205902109
  • Astronomy

    • You have access
      Kepler constraints on planets near hot Jupiters
      Jason H. Steffen, Darin Ragozzine, Daniel C. Fabrycky, Joshua A. Carter, Eric B. Ford, Matthew J. Holman, Jason F. Rowe, William F. Welsh, William J. Borucki, Alan P. Boss, David R. Ciardi, and Samuel N. Quinn
      PNAS May 22, 2012 109 (21) 7982-7987; https://doi.org/10.1073/pnas.1120970109
  • Chemistry

    • You have access
      Unraveling quantum mechanical effects in water using isotopic fractionation
      Thomas E. Markland and B. J. Berne
      PNAS May 22, 2012 109 (21) 7988-7991; https://doi.org/10.1073/pnas.1203365109
    • Open Access
      Uniform hexagonal graphene flakes and films grown on liquid copper surface
      • From the Cover
      Dechao Geng, Bin Wu, Yunlong Guo, Liping Huang, Yunzhou Xue, Jianyi Chen, Gui Yu, Lang Jiang, Wenping Hu, and Yunqi Liu
      PNAS May 22, 2012 109 (21) 7992-7996; https://doi.org/10.1073/pnas.1200339109
    • You have access
      Dynamics of the O(3P) + CHD3(vCH = 0,1) reactions on an accurate ab initio potential energy surface
      Gábor Czakó and Joel M. Bowman
      PNAS May 22, 2012 109 (21) 7997-8001; https://doi.org/10.1073/pnas.1202307109
    • Open Access
      Organization, dynamics, and segregation of Ras nanoclusters in membrane domains
      Lorant Janosi, Zhenlong Li, John F. Hancock, and Alemayehu A. Gorfe
      PNAS May 22, 2012 109 (21) 8097-8102; https://doi.org/10.1073/pnas.1200773109
  • Earth, Atmospheric, and Planetary Sciences

    • Open Access
      Further constraints on the Chauvet cave artwork elaboration
      Benjamin Sadier, Jean-Jacques Delannoy, Lucilla Benedetti, Didier L. Bourlès, Stéphane Jaillet, Jean-Michel Geneste, Anne-Elisabeth Lebatard, and Maurice Arnold
      PNAS May 22, 2012 109 (21) 8002-8006; https://doi.org/10.1073/pnas.1118593109
  • Engineering

    • You have access
      Human spermatozoa migration in microchannels reveals boundary-following navigation
      Petr Denissenko, Vasily Kantsler, David J. Smith, and Jackson Kirkman-Brown
      PNAS May 22, 2012 109 (21) 8007-8010; https://doi.org/10.1073/pnas.1202934109
    • You have access
      Revival of the abandoned therapeutic wortmannin by nanoparticle drug delivery
      Shrirang Karve, Michael E. Werner, Rohit Sukumar, Natalie D. Cummings, Jonathan A. Copp, Edina C. Wang, Chenxi Li, Manish Sethi, Ronald C. Chen, Michael E. Pacold, and Andrew Z. Wang
      PNAS May 22, 2012 109 (21) 8230-8235; https://doi.org/10.1073/pnas.1120508109
  • Physics

    • Open Access
      Direct observation of turbulent magnetic fields in hot, dense laser produced plasmas
      Sudipta Mondal, V. Narayanan, Wen Jun Ding, Amit D. Lad, Biao Hao, Saima Ahmad, Wei Min Wang, Zheng Ming Sheng, Sudip Sengupta, Predhiman Kaw, Amita Das, and G. Ravindra Kumar
      PNAS May 22, 2012 109 (21) 8011-8015; https://doi.org/10.1073/pnas.1200753109
    • You have access
      Near-field manipulation of spectroscopic selection rules on the nanoscale
      Prashant K. Jain, Debraj Ghosh, Roi Baer, Eran Rabani, and A. Paul Alivisatos
      PNAS May 22, 2012 109 (21) 8016-8019; https://doi.org/10.1073/pnas.1121319109
    • Open Access
      Two distinct overstretched DNA structures revealed by single-molecule thermodynamics measurements
      Xinghua Zhang, Hu Chen, Hongxia Fu, Patrick S. Doyle, and Jie Yan
      PNAS May 22, 2012 109 (21) 8103-8108; https://doi.org/10.1073/pnas.1109824109
    • Open Access
      Generic temperature compensation of biological clocks by autonomous regulation of catalyst concentration
      Tetsuhiro S. Hatakeyama and Kunihiko Kaneko
      PNAS May 22, 2012 109 (21) 8109-8114; https://doi.org/10.1073/pnas.1120711109

Social Sciences

  • Anthropology

    • You have access
      Early evidence of the ballgame in Oaxaca, Mexico
      Jeffrey P. Blomster
      PNAS May 22, 2012 109 (21) 8020-8025; https://doi.org/10.1073/pnas.1203483109
  • Economic Sciences

    • Open Access
      The genetic architecture of economic and political preferences
      Daniel J. Benjamin, David Cesarini, Matthijs J. H. M. van der Loos, Christopher T. Dawes, Philipp D. Koellinger, Patrik K. E. Magnusson, Christopher F. Chabris, Dalton Conley, David Laibson, Magnus Johannesson, and Peter M. Visscher
      PNAS May 22, 2012 109 (21) 8026-8031; https://doi.org/10.1073/pnas.1120666109
  • Environmental Sciences

    • Open Access
      Co-occurrence of linguistic and biological diversity in biodiversity hotspots and high biodiversity wilderness areas
      L. J. Gorenflo, Suzanne Romaine, Russell A. Mittermeier, and Kristen Walker-Painemilla
      PNAS May 22, 2012 109 (21) 8032-8037; https://doi.org/10.1073/pnas.1117511109
  • Psychological and Cognitive Sciences

    • You have access
      Disclosing information about the self is intrinsically rewarding
      Diana I. Tamir and Jason P. Mitchell
      PNAS May 22, 2012 109 (21) 8038-8043; https://doi.org/10.1073/pnas.1202129109

Biological Sciences

  • Anthropology

    • Open Access
      Further constraints on the Chauvet cave artwork elaboration
      Benjamin Sadier, Jean-Jacques Delannoy, Lucilla Benedetti, Didier L. Bourlès, Stéphane Jaillet, Jean-Michel Geneste, Anne-Elisabeth Lebatard, and Maurice Arnold
      PNAS May 22, 2012 109 (21) 8002-8006; https://doi.org/10.1073/pnas.1118593109
    • You have access
      Natural and sexual selection in a monogamous historical human population
      Alexandre Courtiol, Jenni E. Pettay, Markus Jokela, Anna Rotkirch, and Virpi Lummaa
      PNAS May 22, 2012 109 (21) 8044-8049; https://doi.org/10.1073/pnas.1118174109
  • Applied Biological Sciences

    • You have access
      KLF15 negatively regulates estrogen-induced epithelial cell proliferation by inhibition of DNA replication licensing
      Sanhita Ray and Jeffrey W. Pollard
      PNAS May 22, 2012 109 (21) E1334-E1343; https://doi.org/10.1073/pnas.1118515109
  • Biochemistry

    • You have access
      Gene 5.5 protein of bacteriophage T7 in complex with Escherichia coli nucleoid protein H-NS and transfer RNA masks transfer RNA priming in T7 DNA replication
      Bin Zhu, Seung-Joo Lee, Min Tan, En-Duo Wang, and Charles C. Richardson
      PNAS May 22, 2012 109 (21) 8050-8055; https://doi.org/10.1073/pnas.1205990109
    • You have access
      Role of phosphorylation of Cdc20 in p31comet-stimulated disassembly of the mitotic checkpoint complex
      Shirly Miniowitz-Shemtov, Esther Eytan, Dvora Ganoth, Danielle Sitry-Shevah, Elena Dumin, and Avram Hershko
      PNAS May 22, 2012 109 (21) 8056-8060; https://doi.org/10.1073/pnas.1204081109
    • You have access
      Monomeric site-specific nucleases for genome editing
      Benjamin P. Kleinstiver, Jason M. Wolfs, Tomasz Kolaczyk, Alanna K. Roberts, Sherry X. Hu, and David R. Edgell
      PNAS May 22, 2012 109 (21) 8061-8066; https://doi.org/10.1073/pnas.1117984109
    • Open Access
      A short adaptive path from DNA to RNA polymerases
      Christopher Cozens, Vitor B. Pinheiro, Alexandra Vaisman, Roger Woodgate, and Philipp Holliger
      PNAS May 22, 2012 109 (21) 8067-8072; https://doi.org/10.1073/pnas.1120964109
    • You have access
      Nanosensing protein allostery using a bivalent mouse double minute two (MDM2) assay
      Anna F. Robson, Ted R. Hupp, Fiona Lickiss, Kathryn L. Ball, Karen Faulds, and Duncan Graham
      PNAS May 22, 2012 109 (21) 8073-8078; https://doi.org/10.1073/pnas.1116637109
    • You have access
      RNA surveillance is required for endoplasmic reticulum homeostasis
      Kenjiro Sakaki, Sawako Yoshina, Xiaohua Shen, Jaeseok Han, Melinda R. DeSantis, Mon Xiong, Shohei Mitani, and Randal J. Kaufman
      PNAS May 22, 2012 109 (21) 8079-8084; https://doi.org/10.1073/pnas.1110589109
    • You have access
      Control of neuronal differentiation by sumoylation of BRAF35, a subunit of the LSD1-CoREST histone demethylase complex
      María Ceballos-Chávez, Sabrina Rivero, Pablo García-Gutiérrez, Manuel Rodríguez-Paredes, Mario García-Domínguez, Shomi Bhattacharya, and José C. Reyes
      PNAS May 22, 2012 109 (21) 8085-8090; https://doi.org/10.1073/pnas.1121522109
    • You have access
      Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNA
      Atanu Maiti, Muhammad S. Noon, Alexander D. MacKerell Jr., Edwin Pozharski, and Alexander C. Drohat
      PNAS May 22, 2012 109 (21) 8091-8096; https://doi.org/10.1073/pnas.1201010109
  • Biophysics and Computational Biology

    • You have access
      Phantom tones and suppressive masking by active nonlinear oscillation of the hair-cell bundle
      Jérémie Barral and Pascal Martin
      PNAS May 22, 2012 109 (21) E1344-E1351; https://doi.org/10.1073/pnas.1202426109
    • Open Access
      Organization, dynamics, and segregation of Ras nanoclusters in membrane domains
      Lorant Janosi, Zhenlong Li, John F. Hancock, and Alemayehu A. Gorfe
      PNAS May 22, 2012 109 (21) 8097-8102; https://doi.org/10.1073/pnas.1200773109
    • Open Access
      Two distinct overstretched DNA structures revealed by single-molecule thermodynamics measurements
      Xinghua Zhang, Hu Chen, Hongxia Fu, Patrick S. Doyle, and Jie Yan
      PNAS May 22, 2012 109 (21) 8103-8108; https://doi.org/10.1073/pnas.1109824109
    • Open Access
      Generic temperature compensation of biological clocks by autonomous regulation of catalyst concentration
      Tetsuhiro S. Hatakeyama and Kunihiko Kaneko
      PNAS May 22, 2012 109 (21) 8109-8114; https://doi.org/10.1073/pnas.1120711109
    • You have access
      Active DNA unwinding dynamics during processive DNA replication
      José A. Morin, Francisco J. Cao, José M. Lázaro, J. Ricardo Arias-Gonzalez, José M. Valpuesta, José L. Carrascosa, Margarita Salas, and Borja Ibarra
      PNAS May 22, 2012 109 (21) 8115-8120; https://doi.org/10.1073/pnas.1204759109
    • You have access
      Shifting hydrogen bonds may produce flexible transmembrane helices
      Zheng Cao and James U. Bowie
      PNAS May 22, 2012 109 (21) 8121-8126; https://doi.org/10.1073/pnas.1201298109
    • Open Access
      Evolution of oligomeric state through geometric coupling of protein interfaces
      Tina Perica, Cyrus Chothia, and Sarah A. Teichmann
      PNAS May 22, 2012 109 (21) 8127-8132; https://doi.org/10.1073/pnas.1120028109
    • You have access
      Depolymerization dynamics of individual filaments of bacterial cytoskeletal protein FtsZ
      Pablo Mateos-Gil, Alfonso Paez, Ines Hörger, Germán Rivas, Miguel Vicente, Pedro Tarazona, and Marisela Vélez
      PNAS May 22, 2012 109 (21) 8133-8138; https://doi.org/10.1073/pnas.1204844109
    • You have access
      Folding helical proteins in explicit solvent using dihedral-biased tempering
      Cheng Zhang and Jianpeng Ma
      PNAS May 22, 2012 109 (21) 8139-8144; https://doi.org/10.1073/pnas.1112143109
  • Cell Biology

    • You have access
      Diurnal, localized exposure of phosphatidylserine by rod outer segment tips in wild-type but not Itgb5−/− or Mfge8−/− mouse retina
      Linda Ruggiero, Mark P. Connor, Jeannie Chen, Ralf Langen, and Silvia C. Finnemann
      PNAS May 22, 2012 109 (21) 8145-8148; https://doi.org/10.1073/pnas.1121101109
    • You have access
      Mixed-lineage kinase 3 phosphorylates prolyl-isomerase Pin1 to regulate its nuclear translocation and cellular function
      Velusamy Rangasamy, Rajakishore Mishra, Gautam Sondarva, Subhasis Das, Tae Ho Lee, Joanna C. Bakowska, Guri Tzivion, James S. Malter, Basabi Rana, Kun Ping Lu, Anumantha Kanthasamy, and Ajay Rana
      PNAS May 22, 2012 109 (21) 8149-8154; https://doi.org/10.1073/pnas.1200804109
    • Open Access
      Choline-releasing glycerophosphodiesterase EDI3 drives tumor cell migration and metastasis
      Joanna D. Stewart, Rosemarie Marchan, Michaela S. Lesjak, Joerg Lambert, Roland Hergenroeder, James K. Ellis, Chung-Ho Lau, Hector C. Keun, Gerd Schmitz, Juergen Schiller, Mandy Eibisch, Christian Hedberg, Herbert Waldmann, Ekkehart Lausch, Berno Tanner, Jalid Sehouli, Jens Sagemueller, Hagen Staude, Eric Steiner, and Jan G. Hengstler
      PNAS May 22, 2012 109 (21) 8155-8160; https://doi.org/10.1073/pnas.1117654109
    • You have access
      The chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positions
      Wenbing Xie, Te Ling, Yonggang Zhou, Weijun Feng, Qiaoyun Zhu, Henk G. Stunnenberg, Ingrid Grummt, and Wei Tao
      PNAS May 22, 2012 109 (21) 8161-8166; https://doi.org/10.1073/pnas.1201262109
  • Developmental Biology

    • You have access
      Human spermatozoa migration in microchannels reveals boundary-following navigation
      Petr Denissenko, Vasily Kantsler, David J. Smith, and Jackson Kirkman-Brown
      PNAS May 22, 2012 109 (21) 8007-8010; https://doi.org/10.1073/pnas.1202934109
    • You have access
      Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea
      Renjie Chai, Bryan Kuo, Tian Wang, Eric J. Liaw, Anping Xia, Taha A. Jan, Zhiyong Liu, Makoto M. Taketo, John S. Oghalai, Roeland Nusse, Jian Zuo, and Alan G. Cheng
      PNAS May 22, 2012 109 (21) 8167-8172; https://doi.org/10.1073/pnas.1202774109
    • You have access
      Control of bone resorption in mice by Schnurri-3
      Marc N. Wein, Dallas C. Jones, Jae-Hyuck Shim, Antonios O. Aliprantis, Rosalyn Sulyanto, Vanja Lazarevic, Sandra L. Poliachik, Ted S. Gross, and Laurie H. Glimcher
      PNAS May 22, 2012 109 (21) 8173-8178; https://doi.org/10.1073/pnas.1205848109
    • You have access
      Replacing the first-generation dentition in pufferfish with a unique beak
      • From the Cover
      Gareth J. Fraser, Ralf Britz, Andie Hall, Zerina Johanson, and Moya M. Smith
      PNAS May 22, 2012 109 (21) 8179-8184; https://doi.org/10.1073/pnas.1119635109
  • Ecology

    • You have access
      Predator transitory spillover induces trophic cascades in ecological sinks
      • From the Cover
      Michele Casini, Thorsten Blenckner, Christian Möllmann, Anna Gårdmark, Martin Lindegren, Marcos Llope, Georgs Kornilovs, Maris Plikshs, and Nils Christian Stenseth
      PNAS May 22, 2012 109 (21) 8185-8189; https://doi.org/10.1073/pnas.1113286109
  • Environmental Sciences

    • You have access
      Bisphenol A alters the development of the rhesus monkey mammary gland
      Andrew P. Tharp, Maricel V. Maffini, Patricia A. Hunt, Catherine A. VandeVoort, Carlos Sonnenschein, and Ana M. Soto
      PNAS May 22, 2012 109 (21) 8190-8195; https://doi.org/10.1073/pnas.1120488109
    • You have access
      Identification of Chinese plague foci from long-term epidemiological data
      Tamara Ben-Ari, Simon Neerinckx, Lydiane Agier, Bernard Cazelles, Lei Xu, Zhibin Zhang, Xiye Fang, Shuchun Wang, Qiyong Liu, and Nils C. Stenseth
      PNAS May 22, 2012 109 (21) 8196-8201; https://doi.org/10.1073/pnas.1110585109
  • Evolution

    • Open Access
      Amino acid coevolution induces an evolutionary Stokes shift
      David D. Pollock, Grant Thiltgen, and Richard A. Goldstein
      PNAS May 22, 2012 109 (21) E1352-E1359; https://doi.org/10.1073/pnas.1120084109
    • You have access
      Reconstructing the origin and spread of horse domestication in the Eurasian steppe
      • From the Cover
      Vera Warmuth, Anders Eriksson, Mim Ann Bower, Graeme Barker, Elizabeth Barrett, Bryan Kent Hanks, Shuicheng Li, David Lomitashvili, Maria Ochir-Goryaeva, Grigory V. Sizonov, Vasiliy Soyonov, and Andrea Manica
      PNAS May 22, 2012 109 (21) 8202-8206; https://doi.org/10.1073/pnas.1111122109
    • You have access
      W chromosome expression responds to female-specific selection
      Hooman K. Moghadam, Marie A. Pointer, Alison E. Wright, Sofia Berlin, and Judith E. Mank
      PNAS May 22, 2012 109 (21) 8207-8211; https://doi.org/10.1073/pnas.1202721109
  • Genetics

    • Open Access
      A common X-linked inborn error of carnitine biosynthesis may be a risk factor for nondysmorphic autism
      • Inaugural Article
      Patrícia B. S. Celestino-Soper, Sara Violante, Emily L. Crawford, Rui Luo, Anath C. Lionel, Elsa Delaby, Guiqing Cai, Bekim Sadikovic, Kwanghyuk Lee, Charlene Lo, Kun Gao, Richard E. Person, Timothy J. Moss, Jennifer R. German, Ni Huang, Marwan Shinawi, Diane Treadwell-Deering, Peter Szatmari, Wendy Roberts, Bridget Fernandez, Richard J. Schroer, Roger E. Stevenson, Joseph D. Buxbaum, Catalina Betancur, Stephen W. Scherer, Stephan J. Sanders, Daniel H. Geschwind, James S. Sutcliffe, Matthew E. Hurles, Ronald J. A. Wanders, Chad A. Shaw, Suzanne M. Leal, Edwin H. Cook Jr., Robin P. Goin-Kochel, Frédéric M. Vaz, and Arthur L. Beaudet
      PNAS May 22, 2012 109 (21) 7974-7981; https://doi.org/10.1073/pnas.1120210109
    • Open Access
      The genetic architecture of economic and political preferences
      Daniel J. Benjamin, David Cesarini, Matthijs J. H. M. van der Loos, Christopher T. Dawes, Philipp D. Koellinger, Patrik K. E. Magnusson, Christopher F. Chabris, Dalton Conley, David Laibson, Magnus Johannesson, and Peter M. Visscher
      PNAS May 22, 2012 109 (21) 8026-8031; https://doi.org/10.1073/pnas.1120666109
    • You have access
      A cluster of cooperating tumor-suppressor gene candidates in chromosomal deletions
      Wen Xue, Thomas Kitzing, Stephanie Roessler, Johannes Zuber, Alexander Krasnitz, Nikolaus Schultz, Kate Revill, Susann Weissmueller, Amy R. Rappaport, Janelle Simon, Jack Zhang, Weijun Luo, James Hicks, Lars Zender, Xin Wei Wang, Scott Powers, Michael Wigler, and Scott W. Lowe
      PNAS May 22, 2012 109 (21) 8212-8217; https://doi.org/10.1073/pnas.1206062109
    • You have access
      Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis
      Martha C. Castaño Betancourt, Frederic Cailotto, Hanneke J. Kerkhof, Frederique M. F. Cornelis, Sally A. Doherty, Deborah J. Hart, Albert Hofman, Frank P. Luyten, Rose A. Maciewicz, Massimo Mangino, Sarah Metrustry, Kenneth Muir, Marjolein J. Peters, Fernando Rivadeneira, Maggie Wheeler, Weiya Zhang, Nigel Arden, Tim D. Spector, Andre G. Uitterlinden, Michael Doherty, Rik J. U. Lories, Ana M. Valdes, and Joyce B. J. van Meurs
      PNAS May 22, 2012 109 (21) 8218-8223; https://doi.org/10.1073/pnas.1119899109
    • You have access
      Genetic coregulation of age of female sexual maturation and lifespan through circulating IGF1 among inbred mouse strains
      Rong Yuan, Qingying Meng, Jaya Nautiyal, Kevin Flurkey, Shirng-Wern Tsaih, Rebecca Krier, Malcolm G. Parker, David E. Harrison, and Beverly Paigen
      PNAS May 22, 2012 109 (21) 8224-8229; https://doi.org/10.1073/pnas.1121113109
  • Immunology

    • You have access
      Janus-faced liposomes enhance antimicrobial innate immune response in Mycobacterium tuberculosis infection
      Emanuela Greco, Gianluca Quintiliani, Marilina B. Santucci, Annalucia Serafino, Anna Rita Ciccaglione, Cinzia Marcantonio, Massimiliano Papi, Giuseppe Maulucci, Giovanni Delogu, Angelo Martino, Delia Goletti, Loredana Sarmati, Massimo Andreoni, Alfonso Altieri, Mario Alma, Nadia Caccamo, Diana Di Liberto, Marco De Spirito, Nigel D. Savage, Roberto Nisini, Francesco Dieli, Tom H. Ottenhoff, and Maurizio Fraziano
      PNAS May 22, 2012 109 (21) E1360-E1368; https://doi.org/10.1073/pnas.1200484109
  • Medical Sciences

    • You have access
      Protection from liver fibrosis by a peroxisome proliferator-activated receptor δ agonist
      Keiko Iwaisako, Michael Haimerl, Yong-Han Paik, Kojiro Taura, Yuzo Kodama, Claude Sirlin, Elizabeth Yu, Ruth T. Yu, Michael Downes, Ronald M. Evans, David A. Brenner, and Bernd Schnabl
      PNAS May 22, 2012 109 (21) E1369-E1376; https://doi.org/10.1073/pnas.1202464109
    • You have access
      A Sleeping Beauty mutagenesis screen reveals a tumor suppressor role for Ncoa2/Src-2 in liver cancer
      Kathryn A. O’Donnell, Vincent W. Keng, Brian York, Erin L. Reineke, Daekwan Seo, Danhua Fan, Kevin A. T. Silverstein, Christina T. Schrum, Wei Rose Xie, Loris Mularoni, Sarah J. Wheelan, Michael S. Torbenson, Bert W. O’Malley, David A. Largaespada, and Jef D. Boeke
      PNAS May 22, 2012 109 (21) E1377-E1386; https://doi.org/10.1073/pnas.1115433109
    • You have access
      Inversion of neurovascular coupling by subarachnoid blood depends on large-conductance Ca2+-activated K+ (BK) channels
      Masayo Koide, Adrian D. Bonev, Mark T. Nelson, and George C. Wellman
      PNAS May 22, 2012 109 (21) E1387-E1395; https://doi.org/10.1073/pnas.1121359109
    • You have access
      Revival of the abandoned therapeutic wortmannin by nanoparticle drug delivery
      Shrirang Karve, Michael E. Werner, Rohit Sukumar, Natalie D. Cummings, Jonathan A. Copp, Edina C. Wang, Chenxi Li, Manish Sethi, Ronald C. Chen, Michael E. Pacold, and Andrew Z. Wang
      PNAS May 22, 2012 109 (21) 8230-8235; https://doi.org/10.1073/pnas.1120508109
    • Open Access
      Reversal of muscle insulin resistance by weight reduction in young, lean, insulin-resistant offspring of parents with type 2 diabetes
      Kitt Falk Petersen, Sylvie Dufour, Katsutaro Morino, Peter S. Yoo, Gary W. Cline, and Gerald I. Shulman
      PNAS May 22, 2012 109 (21) 8236-8240; https://doi.org/10.1073/pnas.1205675109
    • Open Access
      Aristolochic acid-associated urothelial cancer in Taiwan
      • From the Cover
      Chung-Hsin Chen, Kathleen G. Dickman, Masaaki Moriya, Jiri Zavadil, Viktoriya S. Sidorenko, Karen L. Edwards, Dmitri V. Gnatenko, Lin Wu, Robert J. Turesky, Xue-Ru Wu, Yeong-Shiau Pu, and Arthur P. Grollman
      PNAS May 22, 2012 109 (21) 8241-8246; https://doi.org/10.1073/pnas.1119920109
    • Open Access
      Memory B cells are a more reliable archive for historical antimalarial responses than plasma antibodies in no-longer exposed children
      Francis Maina Ndungu, Ally Olotu, Jedidah Mwacharo, Mary Nyonda, Jordan Apfeld, Lazarus K. Mramba, Gregory W. Fegan, Philip Bejon, and Kevin Marsh
      PNAS May 22, 2012 109 (21) 8247-8252; https://doi.org/10.1073/pnas.1200472109
    • You have access
      Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency
      Quentin McAfee, Zhihui Zhang, Arabinda Samanta, Samuel M. Levi, Xiao-Hong Ma, Shengfu Piao, John P. Lynch, Takeshi Uehara, Antonia R. Sepulveda, Lisa E. Davis, Jeffrey D. Winkler, and Ravi K. Amaravadi
      PNAS May 22, 2012 109 (21) 8253-8258; https://doi.org/10.1073/pnas.1118193109
  • Microbiology

    • You have access
      RNAs in Epstein–Barr virions control early steps of infection
      Simon Jochum, Romana Ruiss, Andreas Moosmann, Wolfgang Hammerschmidt, and Reinhard Zeidler
      PNAS May 22, 2012 109 (21) E1396-E1404; https://doi.org/10.1073/pnas.1115906109
    • You have access
      Structural basis for sigma factor mimicry in the general stress response of Alphaproteobacteria
      Sébastien Campagne, Fred F. Damberger, Andreas Kaczmarczyk, Anne Francez-Charlot, Frédéric H.-T. Allain, and Julia A. Vorholt
      PNAS May 22, 2012 109 (21) E1405-E1414; https://doi.org/10.1073/pnas.1117003109
    • You have access
      Structural basis of a protein partner switch that regulates the general stress response of α-proteobacteria
      Julien Herrou, Grant Rotskoff, Yun Luo, Benoît Roux, and Sean Crosson
      PNAS May 22, 2012 109 (21) E1415-E1423; https://doi.org/10.1073/pnas.1116887109
    • Open Access
      Density-dependent fitness benefits in quorum-sensing bacterial populations
      Sophie E. Darch, Stuart A. West, Klaus Winzer, and Stephen P. Diggle
      PNAS May 22, 2012 109 (21) 8259-8263; https://doi.org/10.1073/pnas.1118131109
    • You have access
      Activation of 5′-3′ exoribonuclease Xrn1 by cofactor Dcs1 is essential for mitochondrial function in yeast
      Flore Sinturel, Dominique Bréchemier-Baey, Megerditch Kiledjian, Ciarán Condon, and Lionel Bénard
      PNAS May 22, 2012 109 (21) 8264-8269; https://doi.org/10.1073/pnas.1120090109
  • Neuroscience

    • You have access
      Disclosing information about the self is intrinsically rewarding
      Diana I. Tamir and Jason P. Mitchell
      PNAS May 22, 2012 109 (21) 8038-8043; https://doi.org/10.1073/pnas.1202129109
    • Open Access
      Detecting activity-evoked pH changes in human brain
      Vincent A. Magnotta, Hye-Young Heo, Brian J. Dlouhy, Nader S. Dahdaleh, Robin L. Follmer, Daniel R. Thedens, Michael J. Welsh, and John A. Wemmie
      PNAS May 22, 2012 109 (21) 8270-8273; https://doi.org/10.1073/pnas.1205902109
    • Open Access
      Functional imaging reveals rapid reorganization of cortical activity after parietal inactivation in monkeys
      Melanie Wilke, Igor Kagan, and Richard A. Andersen
      PNAS May 22, 2012 109 (21) 8274-8279; https://doi.org/10.1073/pnas.1204789109
    • You have access
      Connexin 43 controls the multipolar phase of neuronal migration to the cerebral cortex
      Xiuxin Liu, Lin Sun, Masaaki Torii, and Pasko Rakic
      PNAS May 22, 2012 109 (21) 8280-8285; https://doi.org/10.1073/pnas.1205880109
    • Open Access
      Cumulative lesioning of respiratory interneurons disrupts and precludes motor rhythms in vitro
      John A. Hayes, Xueying Wang, and Christopher A. Del Negro
      PNAS May 22, 2012 109 (21) 8286-8291; https://doi.org/10.1073/pnas.1200912109
    • Open Access
      Mechanisms contributing to central excitability changes during hearing loss
      Nadia Pilati, Matias J. Ison, Matthew Barker, Mike Mulheran, Charles H. Large, Ian D. Forsythe, John Matthias, and Martine Hamann
      PNAS May 22, 2012 109 (21) 8292-8297; https://doi.org/10.1073/pnas.1116981109
  • Pharmacology

    • Open Access
      Generation of quinolone antimalarials targeting the Plasmodium falciparum mitochondrial respiratory chain for the treatment and prophylaxis of malaria
      Giancarlo A. Biagini, Nicholas Fisher, Alison E. Shone, Murad A. Mubaraki, Abhishek Srivastava, Alisdair Hill, Thomas Antoine, Ashley J. Warman, Jill Davies, Chandrakala Pidathala, Richard K. Amewu, Suet C. Leung, Raman Sharma, Peter Gibbons, David W. Hong, Bénédicte Pacorel, Alexandre S. Lawrenson, Sitthivut Charoensutthivarakul, Lee Taylor, Olivier Berger, Alison Mbekeani, Paul A. Stocks, Gemma L. Nixon, James Chadwick, Janet Hemingway, Michael J. Delves, Robert E. Sinden, Anne-Marie Zeeman, Clemens H. M. Kocken, Neil G. Berry, Paul M. O’Neill, and Stephen A. Ward
      PNAS May 22, 2012 109 (21) 8298-8303; https://doi.org/10.1073/pnas.1205651109
    • You have access
      Ligands and signaling proteins govern the conformational landscape explored by a G protein-coupled receptor
      Sophie Mary, Marjorie Damian, Maxime Louet, Nicolas Floquet, Jean-Alain Fehrentz, Jacky Marie, Jean Martinez, and Jean-Louis Banères
      PNAS May 22, 2012 109 (21) 8304-8309; https://doi.org/10.1073/pnas.1119881109
  • Plant Biology

    • You have access
      Distinct phytochrome actions in nonvascular plants revealed by targeted inactivation of phytobilin biosynthesis
      Yu-Rong Chen, Yi-shin Su, and Shih-Long Tu
      PNAS May 22, 2012 109 (21) 8310-8315; https://doi.org/10.1073/pnas.1201744109
    • You have access
      Rhizobium–legume symbiosis shares an exocytotic pathway required for arbuscule formation
      Sergey Ivanov, Elena E. Fedorova, Erik Limpens, Stephane De Mita, Andrea Genre, Paola Bonfante, and Ton Bisseling
      PNAS May 22, 2012 109 (21) 8316-8321; https://doi.org/10.1073/pnas.1200407109
    • Open Access
      Lysine63-linked ubiquitylation of PIN2 auxin carrier protein governs hormonally controlled adaptation of Arabidopsis root growth
      Johannes Leitner, Jan Petrášek, Konstantin Tomanov, Katarzyna Retzer, Markéta Pařezová, Barbara Korbei, Andreas Bachmair, Eva Zažímalová, and Christian Luschnig
      PNAS May 22, 2012 109 (21) 8322-8327; https://doi.org/10.1073/pnas.1200824109
    • Open Access
      Mutation at the circadian clock gene EARLY MATURITY 8 adapts domesticated barley (Hordeum vulgare) to short growing seasons
      Sebastien Faure, Adrian S. Turner, Damian Gruszka, Vangelis Christodoulou, Seth J. Davis, Maria von Korff, and David A. Laurie
      PNAS May 22, 2012 109 (21) 8328-8333; https://doi.org/10.1073/pnas.1120496109
  • Population Biology

    • Open Access
      Environmental biodiversity, human microbiota, and allergy are interrelated
      Ilkka Hanski, Leena von Hertzen, Nanna Fyhrquist, Kaisa Koskinen, Kaisa Torppa, Tiina Laatikainen, Piia Karisola, Petri Auvinen, Lars Paulin, Mika J. Mäkelä, Erkki Vartiainen, Timo U. Kosunen, Harri Alenius, and Tari Haahtela
      PNAS May 22, 2012 109 (21) 8334-8339; https://doi.org/10.1073/pnas.1205624109
  • Systems Biology

    • You have access
      Moment-based inference predicts bimodality in transient gene expression
      Christoph Zechner, Jakob Ruess, Peter Krenn, Serge Pelet, Matthias Peter, John Lygeros, and Heinz Koeppl
      PNAS May 22, 2012 109 (21) 8340-8345; https://doi.org/10.1073/pnas.1200161109
    • You have access
      Design principles of cell circuits with paradoxical components
      Yuval Hart, Yaron E. Antebi, Avraham E. Mayo, Nir Friedman, and Uri Alon
      PNAS May 22, 2012 109 (21) 8346-8351; https://doi.org/10.1073/pnas.1117475109

Corrections

  • You have access
    Correction for Journal Editors and Authors Group, Uncensored exchange of scientific results
    PNAS May 22, 2012 109 (21) 8352; https://doi.org/10.1073/pnas.1206993109
  • You have access
    Correction for Dalin et al., Evolution of the global virtual water trade network
    PNAS May 22, 2012 109 (21) 8353; https://doi.org/10.1073/pnas.1206123109
  • You have access
    Correction for Alexander et al., ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS
    PNAS May 22, 2012 109 (21) 8352; https://doi.org/10.1073/pnas.1206201109
  • You have access
    Correction for Fernandez-Fueyo et al., Comparative genomics of Ceriporiopsis subvermispora and Phanerochaete chrysosporium provide insight into selective ligninolysis
    PNAS May 22, 2012 109 (21) 8352; https://doi.org/10.1073/pnas.1206295109
PreviousNext
Back to top

In this issue

Proceedings of the National Academy of Sciences: 109 (21)
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Ed Board (PDF)
  • Masthead (PDF)
Sign up for alerts

Jump to

  • This Week in PNAS
  • Letters (Online Only)
  • Commentaries
  • Physical Sciences
  • Social Sciences
  • Biological Sciences
  • Corrections

Teaching Resources ad

Site Logo
Powered by HighWire
  • Submit Manuscript
  • Twitter
  • Facebook
  • RSS Feeds
  • Email Alerts

Articles

  • Current Issue
  • Latest Articles
  • Archive

PNAS Portals

  • Classics
  • Front Matter
  • Teaching Resources
  • Anthropology
  • Chemistry
  • Physics
  • Sustainability Science

Information

  • Authors
  • Editorial Board
  • Reviewers
  • Press
  • Site Map

Feedback    Privacy/Legal

Copyright © 2019 National Academy of Sciences. Online ISSN 1091-6490