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Table of Contents
July 24, 2012; vol. 109 no. 30
This Week in PNAS
Letters (Online Only)
- You have accessOxygen is the key factor associated with the difference between in vivo and in vitro effects of antioxidantsShosuke Kojo
- You have accessReply to Kojo: Mechanisms of antioxidant-induced DNA damageJennifer T. Fox, Srilatha Sakamuru, Ruili Huang, Nedelina Teneva, Steven O. Simmons, Menghang Xia, Raymond R. Tice, Christopher P. Austin, and Kyungjae Myung
- You have accessSocietal collapse or transformation, and resilienceLeonie J. Pearson and Craig J. Pearson
- You have accessReply to Pearson and Pearson: Reflections on historical vs. contemporary informationKarl W. Butzer
Profile
Physical Sciences
Applied Mathematics
- Open AccessModeling huanglongbing transmission within a citrus treeChristinah Chiyaka, Burton H. Singer, Susan E. Halbert, J. Glenn Morris Jr., and Ariena H. C. van Bruggen
Applied Physical Sciences
- You have accessTumor radiation response enhancement by acoustical stimulation of the vasculatureGregory J. Czarnota, Raffi Karshafian, Peter N. Burns, Shun Wong, Azza Al Mahrouki, Justin W. Lee, Amanda Caissie, William Tran, Christina Kim, Melissa Furukawa, Emily Wong, and Anoja Giles
- You have accessMagnetic characterization of isolated candidate vertebrate magnetoreceptor cellsStephan H.K. Eder, Hervé Cadiou, Airina Muhamad, Peter A. McNaughton, Joseph L. Kirschvink, and Michael Winklhofer
- You have accessMechanical elasticity as a physical signature of conformational dynamics in a virus particleMilagros Castellanos, Rebeca Pérez, Carolina Carrasco, Mercedes Hernando-Pérez, Julio Gómez-Herrero, Pedro J. de Pablo, and Mauricio G. Mateu
- You have accessMechanism-independent method for predicting response to multidrug combinations in bacteriaKevin Wood, Satoshi Nishida, Eduardo D. Sontag, and Philippe Cluzel
Astronomy
- You have accessAnomalously weak solar convection
- From the Cover
Shravan M. Hanasoge, Thomas L. Duvall Jr., and Katepalli R. SreenivasanSee companion article:
- Helioseismology challenges models of convection- Jul 18, 2012
Chemistry
- You have accessOne-electron oxidation of an oxoiron(IV) complex to form an [O═FeV═NR]+ centerKatherine M. Van Heuvelen, Adam T. Fiedler, Xiaopeng Shan, Raymond F. De Hont, Katlyn K. Meier, Emile L. Bominaar, Eckard Münck, and Lawrence Que Jr.
- You have accessTopical delivery of siRNA-based spherical nucleic acid nanoparticle conjugates for gene regulationDan Zheng, David A. Giljohann, David L. Chen, Matthew D. Massich, Xiao-Qi Wang, Hristo Iordanov, Chad A. Mirkin, and Amy S. Paller
- You have accessPhenanthriplatin, a monofunctional DNA-binding platinum anticancer drug candidate with unusual potency and cellular activity profileGa Young Park, Justin J. Wilson, Ying Song, and Stephen J. Lippard
- You have accessPreparation of unnatural N-to-N and C-to-C protein fusionsMartin D. Witte, Juan J. Cragnolini, Stephanie K. Dougan, Nicholas C. Yoder, Maximilian W. Popp, and Hidde L. Ploegh
Earth, Atmospheric, and Planetary Sciences
- Open AccessImproving aerosol distributions below clouds by assimilating satellite-retrieved cloud droplet numberPablo E. Saide, Gregory R. Carmichael, Scott N. Spak, Patrick Minnis, and J. Kirk Ayers
- Open AccessBedrock displacements in Greenland manifest ice mass variations, climate cycles and climate changeMichael Bevis, John Wahr, Shfaqat A. Khan, Finn Bo Madsen, Abel Brown, Michael Willis, Eric Kendrick, Per Knudsen, Jason E. Box, Tonie van Dam, Dana J. Caccamise II, Bjorn Johns, Thomas Nylen, Robin Abbott, Seth White, Jeremy Miner, Rene Forsberg, Hao Zhou, Jian Wang, Terry Wilson, David Bromwich, and Olivier Francis
- You have accessLarge enantiomeric excesses in primitive meteorites and the diverse effects of water in cosmochemical evolutionSandra Pizzarello, Devin L. Schrader, Adam A. Monroe, and Dante S. Lauretta
See companion article:
- Enantiomeric excesses in meteorites, a supplement- Oct 12, 2012
- You have accessRedox systematics of a magma ocean with variable pressure-temperature gradients and compositionK. Righter and M. S. Ghiorso
Engineering
- You have accessStabilization of vaccines and antibiotics in silk and eliminating the cold chainJeney Zhang, Eleanor Pritchard, Xiao Hu, Thomas Valentin, Bruce Panilaitis, Fiorenzo G. Omenetto, and David L. KaplanPNAS July 24, 2012 109 (30) 11981-11986; first published July 9, 2012. https://doi.org/10.1073/pnas.1206210109
Environmental Sciences
- Open AccessGeochemical evidence for possible natural migration of Marcellus Formation brine to shallow aquifers in Pennsylvania
- From the Cover
Nathaniel R. Warner, Robert B. Jackson, Thomas H. Darrah, Stephen G. Osborn, Adrian Down, Kaiguang Zhao, Alissa White, and Avner VengoshSee companion article:
- Fluid migration from the Marcellus is possible- Dec 10, 2012
Physics
- Open AccessSpeed, dissipation, and error in kinetic proofreadingArvind Murugan, David A. Huse, and Stanislas Leibler
Social Sciences
Economic Sciences
- Open AccessRecursive utility in a Markov environment with stochastic growthLars Peter Hansen and José A. Scheinkman
Psychological and Cognitive Sciences
- Open AccessEvolution of music by public choice
- From the Cover
- Cozzarelli Prize Winner
Robert M. MacCallum, Matthias Mauch, Austin Burt, and Armand M. LeroiSee companion article:
- Fitness landscape of music- Jul 09, 2012
See companion article:
- Psychological bias in cultural evolution- Dec 10, 2012
Sustainability Science
- Open AccessUnobserved time effects confound the identification of climate change impactsMaximilian Auffhammer and Jeffrey R. Vincent
Biological Sciences
Applied Biological Sciences
- You have accessTumor radiation response enhancement by acoustical stimulation of the vasculatureGregory J. Czarnota, Raffi Karshafian, Peter N. Burns, Shun Wong, Azza Al Mahrouki, Justin W. Lee, Amanda Caissie, William Tran, Christina Kim, Melissa Furukawa, Emily Wong, and Anoja Giles
- You have accessTopical delivery of siRNA-based spherical nucleic acid nanoparticle conjugates for gene regulationDan Zheng, David A. Giljohann, David L. Chen, Matthew D. Massich, Xiao-Qi Wang, Hristo Iordanov, Chad A. Mirkin, and Amy S. Paller
- You have accessStabilization of vaccines and antibiotics in silk and eliminating the cold chainJeney Zhang, Eleanor Pritchard, Xiao Hu, Thomas Valentin, Bruce Panilaitis, Fiorenzo G. Omenetto, and David L. KaplanPNAS July 24, 2012 109 (30) 11981-11986; first published July 9, 2012. https://doi.org/10.1073/pnas.1206210109
Biochemistry
- You have accessStructural and functional characterization of the two phosphoinositide binding sites of PROPPINs, a β-propeller protein familyRoswitha Krick, Ricarda A. Busse, Andreea Scacioc, Milena Stephan, Andreas Janshoff, Michael Thumm, and Karin Kühnel
- Open AccessStructural study on the architecture of the bacterial ATP synthase Fo motorJonna K. Hakulinen, Adriana L. Klyszejko, Jan Hoffmann, Luise Eckhardt-Strelau, Bernd Brutschy, Janet Vonck, and Thomas Meier
- You have accessPhenanthriplatin, a monofunctional DNA-binding platinum anticancer drug candidate with unusual potency and cellular activity profileGa Young Park, Justin J. Wilson, Ying Song, and Stephen J. Lippard
- You have accessPreparation of unnatural N-to-N and C-to-C protein fusionsMartin D. Witte, Juan J. Cragnolini, Stephanie K. Dougan, Nicholas C. Yoder, Maximilian W. Popp, and Hidde L. Ploegh
- You have accessATP-dependent conformational dynamics underlie the functional asymmetry of the replicative helicase from a minimalist eukaryoteArtem Y. Lyubimov, Alessandro Costa, Franziska Bleichert, Michael R. Botchan, and James M. Berger
- You have accessEfficient and sequence-independent replication of DNA containing a third base pair establishes a functional six-letter genetic alphabetDenis A. Malyshev, Kirandeep Dhami, Henry T. Quach, Thomas Lavergne, Phillip Ordoukhanian, Ali Torkamani, and Floyd E. Romesberg
- You have accessA designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus endLudovic Pecqueur, Christian Duellberg, Birgit Dreier, Qiyang Jiang, Chunguang Wang, Andreas Plückthun, Thomas Surrey, Benoît Gigant, and Marcel Knossow
- You have accessStructural and energetic basis of ALS-causing mutations in the atypical proline–tyrosine nuclear localization signal of the Fused in Sarcoma protein (FUS)Zi Chao Zhang and Yuh Min Chook
Biophysics and Computational Biology
- You have accessMagnetic characterization of isolated candidate vertebrate magnetoreceptor cellsStephan H.K. Eder, Hervé Cadiou, Airina Muhamad, Peter A. McNaughton, Joseph L. Kirschvink, and Michael Winklhofer
- You have accessMechanical elasticity as a physical signature of conformational dynamics in a virus particleMilagros Castellanos, Rebeca Pérez, Carolina Carrasco, Mercedes Hernando-Pérez, Julio Gómez-Herrero, Pedro J. de Pablo, and Mauricio G. Mateu
- Open AccessSpeed, dissipation, and error in kinetic proofreadingArvind Murugan, David A. Huse, and Stanislas Leibler
- You have accessTranscriptome and methylome interactions in rice hybridsRamakrishna K. Chodavarapu, Suhua Feng, Bo Ding, Stacey A. Simon, David Lopez, Yulin Jia, Guo-Liang Wang, Blake C. Meyers, Steven E. Jacobsen, and Matteo Pellegrini
Cell Biology
- You have accessRab27 and Rab3 sequentially regulate human sperm dense-core granule exocytosisMatías A. Bustos, Ornella Lucchesi, María C. Ruete, Luis S. Mayorga, and Claudia N. Tomes
- You have accessCryoelectron tomography reveals doublet-specific structures and unique interactions in the I1 dyneinThomas Heuser, Cynthia F. Barber, Jianfeng Lin, Jeremy Krell, Matthew Rebesco, Mary E. Porter, and Daniela Nicastro
- You have accessAmyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans-Golgi networkRegina Wai-Yan Choy, Zhiliang Cheng, and Randy Schekman
- Open AccessJNK and PTEN cooperatively control the development of invasive adenocarcinoma of the prostateAnette Hübner, David J. Mulholland, Claire L. Standen, Maria Karasarides, Julie Cavanagh-Kyros, Tamera Barrett, Hongbo Chi, Dale L. Greiner, Cathy Tournier, Charles L. Sawyers, Richard A. Flavell, Hong Wu, and Roger J. Davis
- You have accessPlasminogen activator inhibitor 1 - insulin-like growth factor binding protein 3 cascade regulates stress-induced senescenceDavid J. Elzi, Yanlai Lai, Meihua Song, Kevin Hakala, Susan T. Weintraub, and Yuzuru Shiio
- You have accessThe Sin3a repressor complex is a master regulator of STAT transcriptional activityLaura Icardi, Raffaele Mori, Viola Gesellchen, Sven Eyckerman, Lode De Cauwer, Judith Verhelst, Koen Vercauteren, Xavier Saelens, Philip Meuleman, Geert Leroux-Roels, Karolien De Bosscher, Michael Boutros, and Jan Tavernier
Developmental Biology
- You have accessTmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesisSatoshi Somekawa, Keiichi Imagawa, Hisaki Hayashi, Masahide Sakabe, Tomoko Ioka, Genki E. Sato, Ken Inada, Takaaki Iwamoto, Toshio Mori, Shiro Uemura, Osamu Nakagawa, and Yoshihiko Saito
Ecology
- You have accessCompensatory mechanisms for ameliorating the fundamental trade-off between predator avoidance and foraging
- From the Cover
Jennifer S. Thaler, Scott H. McArt, and Ian Kaplan
Evolution
- Open AccessEvolution of music by public choice
- From the Cover
- Cozzarelli Prize Winner
Robert M. MacCallum, Matthias Mauch, Austin Burt, and Armand M. LeroiSee companion article:
- Fitness landscape of music- Jul 09, 2012
See companion article:
- Psychological bias in cultural evolution- Dec 10, 2012
Genetics
- Open AccessA public resource facilitating clinical use of genomes
- Inaugural Article
Madeleine P. Ball, Joseph V. Thakuria, Alexander Wait Zaranek, Tom Clegg, Abraham M. Rosenbaum, Xiaodi Wu, Misha Angrist, Jong Bhak, Jason Bobe, Matthew J. Callow, Carlos Cano, Michael F. Chou, Wendy K. Chung, Shawn M. Douglas, Preston W. Estep, Athurva Gore, Peter Hulick, Alberto Labarga, Je-Hyuk Lee, Jeantine E. Lunshof, Byung Chul Kim, Jong-Il Kim, Zhe Li, Michael F. Murray, Geoffrey B. Nilsen, Brock A. Peters, Anugraha M. Raman, Hugh Y. Rienhoff, Kimberly Robasky, Matthew T. Wheeler, Ward Vandewege, Daniel B. Vorhaus, Joyce L. Yang, Luhan Yang, John Aach, Euan A. Ashley, Radoje Drmanac, Seong-Jin Kim, Jin Billy Li, Leonid Peshkin, Christine E. Seidman, Jeong-Sun Seo, Kun Zhang, Heidi L. Rehm, and George M. ChurchSee companion article:
- Profile of George M. Church- Apr 02, 2012
- You have accessEffects of a single nucleotide polymorphism in the chicken NK-lysin gene on antimicrobial activity and cytotoxicity of cancer cellsMi Ok Lee, Eun-Hee Kim, Hyun-Jun Jang, Mi Na Park, Hee-Jong Woo, Jae Yong Han, and James E. Womack
- Open AccessMolecular dissection of Neurospora Spore killer meiotic drive elementsThomas M. Hammond, David G. Rehard, Hua Xiao, and Patrick K. T. Shiu
See companion article:
- Meiotic-drive resistance gene- Jul 09, 2012
- Open AccessCritical function for the Ras-GTPase activating protein RASA3 in vertebrate erythropoiesis and megakaryopoiesisLionel Blanc, Steven L. Ciciotte, Babette Gwynn, Gordon J. Hildick-Smith, Eric L. Pierce, Kathleen A. Soltis, Jeffrey D. Cooney, Barry H. Paw, and Luanne L. Peters
Immunology
- Open AccessStructural basis for germ-line gene usage of a potent class of antibodies targeting the CD4-binding site of HIV-1 gp120Anthony P. West Jr., Ron Diskin, Michel C. Nussenzweig, and Pamela J. Bjorkman
- You have accessDefect in regulatory B-cell function and development of systemic autoimmunity in T-cell Ig mucin 1 (Tim-1) mucin domain-mutant miceSheng Xiao, Craig R. Brooks, Chen Zhu, Chuan Wu, Johanna M. Sweere, Sonia Petecka, Ada Yeste, Francisco J. Quintana, Takaharu Ichimura, Raymond A. Sobel, Joseph V. Bonventre, and Vijay K. Kuchroo
- Open AccessHIV-1 envelope trimer elicits more potent neutralizing antibody responses than monomeric gp120James M. Kovacs, Joseph P. Nkolola, Hanqin Peng, Ann Cheung, James Perry, Caroline A. Miller, Michael S. Seaman, Dan H. Barouch, and Bing Chen
- You have accessHematopoietic-specific targeting of influenza A virus reveals replication requirements for induction of antiviral immune responsesRyan A. Langlois, Andrew Varble, Mark A. Chua, Adolfo García-Sastre, and Benjamin R. tenOever
- You have accessInterferon regulatory factor 8 integrates T-cell receptor and cytokine-signaling pathways and drives effector differentiation of CD8 T cellsFumi Miyagawa, Hong Zhang, Atshushi Terunuma, Keiko Ozato, Yutaka Tagaya, and Stephen I. Katz
- You have accessEnhancement of dendritic cell activation via CD40 ligand-expressing γδ T cells is responsible for protective immunity to Plasmodium parasitesShin-Ichi Inoue, Mamoru Niikura, Satoru Takeo, Shoichiro Mineo, Yasushi Kawakami, Akihiko Uchida, Shigeru Kamiya, and Fumie Kobayashi
Microbiology
- You have accessLight regulates attachment, exopolysaccharide production, and nodulation in Rhizobium leguminosarum through a LOV-histidine kinase photoreceptorHernán R. Bonomi, Diana M. Posadas, Gastón Paris, Mariela del Carmen Carrica, Marcus Frederickson, Lía Isabel Pietrasanta, Roberto A. Bogomolni, Angeles Zorreguieta, and Fernando A. Goldbaum
- You have accessAntisense RNA that affects Rhodopseudomonas palustris quorum-sensing signal receptor expressionHidetada Hirakawa, Caroline S. Harwood, Kieran B. Pechter, Amy L. Schaefer, and E. Peter Greenberg
- You have accessEradication of bacterial persisters with antibiotic-generated hydroxyl radicalsSarah Schmidt Grant, Benjamin B. Kaufmann, Nikhilesh S. Chand, Nathan Haseley, and Deborah T. Hung
- You have accessInactivation of a single gene enables microaerobic growth of the obligate anaerobe Bacteroides fragilisBrian M. Meehan, Anthony D. Baughn, Rene Gallegos, and Michael H. Malamy
- You have accessChemotactic signaling via carbohydrate phosphotransferase systems in Escherichia coliSilke Neumann, Karin Grosse, and Victor Sourjik
Neuroscience
- You have accessNeuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy
- From the Cover
Amanda J. Law, Yanhong Wang, Yoshitatsu Sei, Patricio O’Donnell, Patrick Piantadosi, Francesco Papaleo, Richard E. Straub, Wenwei Huang, Craig J. Thomas, Radhakrishna Vakkalanka, Aaron D. Besterman, Barbara K. Lipska, Thomas M. Hyde, Paul J. Harrison, Joel E. Kleinman, and Daniel R. WeinbergerSee companion article:
- A target for schizophrenia treatment- Jul 09, 2012
- You have accessSushi domains confer distinct trafficking profiles on GABAB receptorsSaad Hannan, Megan E. Wilkins, and Trevor G. Smart
- Open AccessRemote control of renal physiology by the intestinal neuropeptide pigment-dispersing factor in DrosophilaAaron D. Talsma, Christo P. Christov, Ana Terriente-Felix, Gerit A. Linneweber, Daniel Perea, Matthew Wayland, Orie T. Shafer, and Irene Miguel-Aliaga
- You have accessInositol hexakisphosphate suppresses excitatory neurotransmission via synaptotagmin-1 C2B domain in the hippocampal neuronShao-Nian Yang, Yue Shi, Guang Yang, Yuxin Li, Lina Yu, Ok-Ho Shin, Taulant Bacaj, Thomas C. Südhof, Jia Yu, and Per-Olof Berggren
- You have accessInterleukin-1R3 mediates interleukin-1–induced potassium current increase through fast activation of Akt kinaseJiang Qian, Ling Zhu, Qiming Li, Natalya Belevych, Qun Chen, Fangli Zhao, Scott Herness, and Ning Quan
- Open AccessSynapse type-independent degradation of the endocannabinoid 2-arachidonoylglycerol after retrograde synaptic suppressionAsami Tanimura, Motokazu Uchigashima, Maya Yamazaki, Naofumi Uesaka, Takayasu Mikuni, Manabu Abe, Kouichi Hashimoto, Masahiko Watanabe, Kenji Sakimura, and Masanobu Kano
- You have accessC-fiber activity-dependent maturation of glycinergic inhibition in the spinal dorsal horn of the postnatal ratStephanie C. Koch, Keri K. Tochiki, Stefan Hirschberg, and Maria Fitzgerald
Pharmacology
- You have accessA soluble bone morphogenetic protein type IA receptor increases bone mass and bone strengthMarc Baud’huin, Nicolas Solban, Milton Cornwall-Brady, Dianne Sako, Yoshimi Kawamoto, Katia Liharska, Darren Lath, Mary L. Bouxsein, Kathryn W. Underwood, Jeffrey Ucran, Ravindra Kumar, Eileen Pobre, Asya Grinberg, Jasbir Seehra, Ernesto Canalis, R. Scott Pearsall, and Peter I. Croucher
Plant Biology
- Open AccessRegulatory switch enforced by basic helix-loop-helix and ACT-domain mediated dimerizations of the maize transcription factor RQue Kong, Sitakanta Pattanaik, Antje Feller, Joshua R. Werkman, Chenglin Chai, Yongqin Wang, Erich Grotewold, and Ling Yuan
- Open AccessModeling huanglongbing transmission within a citrus treeChristinah Chiyaka, Burton H. Singer, Susan E. Halbert, J. Glenn Morris Jr., and Ariena H. C. van Bruggen
- You have accessInsights into salt tolerance from the genome of Thellungiella salsugineaHua-Jun Wu, Zhonghui Zhang, Jun-Yi Wang, Dong-Ha Oh, Maheshi Dassanayake, Binghang Liu, Quanfei Huang, Hai-Xi Sun, Ran Xia, Yaorong Wu, Yi-Nan Wang, Zhao Yang, Yang Liu, Wanke Zhang, Huawei Zhang, Jinfang Chu, Cunyu Yan, Shuang Fang, Jinsong Zhang, Yiqin Wang, Fengxia Zhang, Guodong Wang, Sang Yeol Lee, John M. Cheeseman, Bicheng Yang, Bo Li, Jiumeng Min, Linfeng Yang, Jun Wang, Chengcai Chu, Shou-Yi Chen, Hans J. Bohnert, Jian-Kang Zhu, Xiu-Jie Wang, and Qi Xie
- Open AccessTCP transcription factor, BRANCH ANGLE DEFECTIVE 1 (BAD1), is required for normal tassel branch angle formation in maizeFang Bai, Renata Reinheimer, Diego Durantini, Elizabeth A. Kellogg, and Robert J. Schmidt
- You have accessA phytochrome–phototropin light signaling complex at the plasma membraneKatharina Jaedicke, Anna Lena Lichtenthäler, Rabea Meyberg, Mathias Zeidler, and Jon Hughes
Psychological and Cognitive Sciences
- You have accessMonkeys have a limited form of short-term memory in auditionBrian H. Scott, Mortimer Mishkin, and Pingbo Yin
- You have accessResetting capacity limitations revealed by long-lasting elimination of attentional blink through trainingHoon Choi, Li-Hung Chang, Kazuhisa Shibata, Yuka Sasaki, and Takeo Watanabe
- You have accessAdiponectin is critical in determining susceptibility to depressive behaviors and has antidepressant-like activityJing Liu, Ming Guo, Di Zhang, Shao-Ying Cheng, Meilian Liu, Jun Ding, Philipp E. Scherer, Feng Liu, and Xin-Yun Lu
Systems Biology
- You have accessMechanism-independent method for predicting response to multidrug combinations in bacteriaKevin Wood, Satoshi Nishida, Eduardo D. Sontag, and Philippe Cluzel
Commentaries
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