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About the Cover
September 11, 2012; vol. 109 no. 37
This Week in PNAS
- You have accessIn This Issue
See companion article:
- Gene balance hypothesis- Aug 20, 2012
- Ammonia clathrate hydrates- Aug 20, 2012
- Stability of dense liquid carbon dioxide- Aug 20, 2012
- Soybean susceptible to manufactured nanomaterials- Aug 20, 2012
- Glucagon and diabetes- Aug 13, 2012
- Soybean susceptible to manufactured nanomaterials- Aug 20, 2012
Letters (Online Only)
- You have accessHuman arrival scenarios have a strong influence on interpretations of the late Quaternary extinctionsMatheus S. Lima-Ribeiro, David Nogués-Bravo, Katharine A. Marske, Fernando A. S. Fernandez, Bernardo Araujo, and José Alexandre F. Diniz-Filho
- You have accessReply to Lima-Ribeiro et al.: Human arrival scenarios have little influence on interpretations of late Quaternary extinctionsGraham W. Prescott, David R. Williams, Andrew Balmford, Rhys E. Green, and Andrea Manica
- You have accessEffect of CC chemokine receptor 4 antagonism on the evolution of experimental autoimmune encephalomyelitisShivashankar Othy, Selma Topçu, Srini V. Kaveri, and Jagadeesh Bayry
- You have accessReply to Othy et al.: Dendritic cell-specific expression of CCR4 is required for development of EAEJudith Alferink, Karola Poppensieker, David-Marian Otte, Luisa Klotz, Stefanie Scheu, Wolfgang Maier, and Andreas Zimmer
QnAs
Feature Article
- You have accessEmergence of social complexity among coastal hunter-gatherers in the Atacama Desert of northern Chile
- From the Cover
Pablo A. Marquet, Calogero M. Santoro, Claudio Latorre, Vivien G. Standen, Sebastián R. Abades, Marcelo M. Rivadeneira, Bernardo Arriaza, and Michael E. HochbergSee companion article:
- Adaptive mortuary behavior- Aug 27, 2012
Physical Sciences
Applied Mathematics
- You have accessUniversal mechanism for Anderson and weak localizationMarcel Filoche and Svitlana Mayboroda
Chemistry
- You have accessTargeting collagen strands by photo-triggered triple-helix hybridizationYang Li, Catherine A. Foss, Daniel D. Summerfield, Jefferson J. Doyle, Collin M. Torok, Harry C. Dietz, Martin G. Pomper, and S. Michael Yu
- You have accessPyranopterin conformation defines the function of molybdenum and tungsten enzymesRichard A. Rothery, Benjamin Stein, Matthew Solomonson, Martin L. Kirk, and Joel H. Weiner
- You have accessChemical synthesis and X-ray structure of a heterochiral {D-protein antagonist plus vascular endothelial growth factor} protein complex by racemic crystallographyKalyaneswar Mandal, Maruti Uppalapati, Dana Ault-Riché, John Kenney, Joshua Lowitz, Sachdev S. Sidhu, and Stephen B.H. Kent
- You have accessAmmonia clathrate hydrates as new solid phases for Titan, Enceladus, and other planetary systemsKyuchul Shin, Rajnish Kumar, Konstantin A. Udachin, Saman Alavi, and John A. Ripmeester
See companion article:
- In This Issue- Sep 11, 2012
- You have accessCollective many-body van der Waals interactions in molecular systemsRobert A. DiStasio Jr., O. Anatole von Lilienfeld, and Alexandre Tkatchenko
Earth, Atmospheric, and Planetary Sciences
- Open AccessPerception of climate change
- From the Cover
James Hansen, Makiko Sato, and Reto RuedySee companion article:
- Observed global mean temperature increases- Aug 20, 2012
See companion article:
- Frequency of extreme summer heat- Feb 05, 2013
- Human-made role in local temperature extremes- Mar 19, 2013
- You have accessArthropods in amber from the Triassic PeriodAlexander R. Schmidt, Saskia Jancke, Evert E. Lindquist, Eugenio Ragazzi, Guido Roghi, Paul C. Nascimbene, Kerstin Schmidt, Torsten Wappler, and David A. Grimaldi
- Open AccessBrown carbon and internal mixing in biomass burning particlesDaniel A. Lack, Justin M. Langridge, Roya Bahreini, Christopher D. Cappa, Ann M. Middlebrook, and Joshua P. Schwarz
Physics
- You have accessStability of dense liquid carbon dioxide
- From the Cover
Brian Boates, Amanuel M. Teweldeberhan, and Stanimir A. BonevSee companion article:
- In This Issue- Sep 11, 2012
- You have accessLandau spectrum and twin boundaries of bismuth in the extreme quantum limitZengwei Zhu, Benoît Fauqué, Liam Malone, Arlei Borba Antunes, Yuki Fuseya, and Kamran Behnia
- You have accessManipulating superconducting fluctuations by the Little–Parks–de Gennes effect in ultrasmall Al loopsNeal E. Staley and Ying Liu
Social Sciences
Economic Sciences
- You have accessEvolution of cooperation and skew under imperfect informationErol Akçay, Adam Meirowitz, Kristopher W. Ramsay, and Simon A. Levin
Environmental Sciences
- You have accessEmergence of social complexity among coastal hunter-gatherers in the Atacama Desert of northern Chile
- From the Cover
Pablo A. Marquet, Calogero M. Santoro, Claudio Latorre, Vivien G. Standen, Sebastián R. Abades, Marcelo M. Rivadeneira, Bernardo Arriaza, and Michael E. HochbergSee companion article:
- Adaptive mortuary behavior- Aug 27, 2012
Psychological and Cognitive Sciences
- Open AccessNo third-party punishment in chimpanzeesKatrin Riedl, Keith Jensen, Josep Call, and Michael Tomasello
Biological Sciences
Anthropology
- Open AccessNo third-party punishment in chimpanzeesKatrin Riedl, Keith Jensen, Josep Call, and Michael Tomasello
Applied Biological Sciences
- You have accessTargeting collagen strands by photo-triggered triple-helix hybridizationYang Li, Catherine A. Foss, Daniel D. Summerfield, Jefferson J. Doyle, Collin M. Torok, Harry C. Dietz, Martin G. Pomper, and S. Michael Yu
Biochemistry
- Open AccessGlobal mapping of translation initiation sites in mammalian cells at single-nucleotide resolutionSooncheol Lee, Botao Liu, Soohyun Lee, Sheng-Xiong Huang, Ben Shen, and Shu-Bing Qian
- You have accessPyranopterin conformation defines the function of molybdenum and tungsten enzymesRichard A. Rothery, Benjamin Stein, Matthew Solomonson, Martin L. Kirk, and Joel H. Weiner
- You have accessChemical synthesis and X-ray structure of a heterochiral {D-protein antagonist plus vascular endothelial growth factor} protein complex by racemic crystallographyKalyaneswar Mandal, Maruti Uppalapati, Dana Ault-Riché, John Kenney, Joshua Lowitz, Sachdev S. Sidhu, and Stephen B.H. Kent
- You have accessStructural basis for entropy-driven cellulose binding by a type-A cellulose-binding module (CBM) and bacterial expansinNikolaos Georgelis, Neela H. Yennawar, and Daniel J. Cosgrove
- You have accessStructure of Nectin-2 reveals determinants of homophilic and heterophilic interactions that control cell–cell adhesionDibyendu Samanta, Udupi A. Ramagopal, Rotem Rubinstein, Vladimir Vigdorovich, Stanley G. Nathenson, and Steven C. Almo
- You have accessEvolution of multiple, mutually orthogonal prolyl-tRNA synthetase/tRNA pairs for unnatural amino acid mutagenesis in Escherichia coliAbhishek Chatterjee, Han Xiao, and Peter G. Schultz
- You have accessDynamics of the l-fucose/H+ symporter revealed by fluorescence spectroscopyJunichi Sugihara, Linfeng Sun, Nieng Yan, and H. Ronald Kaback
- You have accessNet −1 frameshifting on a noncanonical sequence in a herpes simplex virus drug-resistant mutant is stimulated by nonstop mRNADongli Pan and Donald M. Coen
- You have accessAn insect-specific P450 oxidative decarbonylase for cuticular hydrocarbon biosynthesisYue Qiu, Claus Tittiger, Claude Wicker-Thomas, Gaëlle Le Goff, Sharon Young, Eric Wajnberg, Thierry Fricaux, Nathalie Taquet, Gary J. Blomquist, and René Feyereisen
- You have accessMARCKS protein mediates hydrogen peroxide regulation of endothelial permeabilityBenjamin Y. Jin, Alison J. Lin, David E. Golan, and Thomas Michel
Biophysics and Computational Biology
- You have accessMyosin IC generates power over a range of loads via a new tension-sensing mechanismMichael J. Greenberg, Tianming Lin, Yale E. Goldman, Henry Shuman, and E. Michael Ostap
- Open AccessNear-atomic resolution structural model of the yeast 26S proteasomeFlorian Beck, Pia Unverdorben, Stefan Bohn, Andreas Schweitzer, Günter Pfeifer, Eri Sakata, Stephan Nickell, Jürgen M. Plitzko, Elizabeth Villa, Wolfgang Baumeister, and Friedrich Förster
- You have accessRealistic simulations of the coupling between the protomotive force and the mechanical rotation of the F0-ATPaseShayantani Mukherjee and Arieh Warshel
- You have accessStructure and dynamics of protein waters revealed by radiolysis and mass spectrometrySayan Gupta, Rhijuta D’Mello, and Mark R. Chance
- Open AccessEscape from Adaptive Conflict follows from weak functional trade-offs and mutational robustnessTobias Sikosek, Hue Sun Chan, and Erich Bornberg-Bauer
- You have accessThe Monod-Wyman-Changeux allosteric model accounts for the quaternary transition dynamics in wild type and a recombinant mutant human hemoglobinMatteo Levantino, Alessandro Spilotros, Marco Cammarata, Giorgio Schirò, Chiara Ardiccioni, Beatrice Vallone, Maurizio Brunori, and Antonio Cupane
- You have accessFoldon unfolding mediates the interconversion between Mpro-C monomer and 3D domain-swapped dimerXue Kang, Nan Zhong, Peng Zou, Shengnan Zhang, Changwen Jin, and Bin Xia
Cell Biology
- Open AccessThe Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domainJohn M. Lamar, Patrick Stern, Hui Liu, Jeffrey W. Schindler, Zhi-Gang Jiang, and Richard O. Hynes
- Open AccessHeritable yeast prions have a highly organized three-dimensional architecture with interfiber structuresHelen R. Saibil, Anja Seybert, Anja Habermann, Juliane Winkler, Mikhail Eltsov, Mario Perkovic, Daniel Castaño-Diez, Margot P. Scheffer, Uta Haselmann, Petr Chlanda, Susan Lindquist, Jens Tyedmers, and Achilleas S. Frangakis
- Open AccessDelaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradationAnnemieke T. van der Goot, Wentao Zhu, Rafael P. Vázquez-Manrique, Renée I. Seinstra, Katja Dettmer, Helen Michels, Francesca Farina, Jasper Krijnen, Ronald Melki, Rogier C. Buijsman, Mariana Ruiz Silva, Karen L. Thijssen, Ido P. Kema, Christian Neri, Peter J. Oefner, and Ellen A. A. Nollen
Developmental Biology
- You have accessAn injury-response mechanism conserved across kingdoms determines entry of the fungus Trichoderma atroviride into developmentMiguel A. Hernández-Oñate, Edgardo U. Esquivel-Naranjo, Artemio Mendoza-Mendoza, Alison Stewart, and Alfredo H. Herrera-Estrella
Ecology
- You have accessSeasonal migration to high latitudes results in major reproductive benefits in an insectJason W. Chapman, James R. Bell, Laura E. Burgin, Donald R. Reynolds, Lars B. Pettersson, Jane K. Hill, Michael B. Bonsall, and Jeremy A. Thomas
Environmental Sciences
- Open AccessSoybean susceptibility to manufactured nanomaterials with evidence for food quality and soil fertility interruption
- From the Cover
John H. Priester, Yuan Ge, Randall E. Mielke, Allison M. Horst, Shelly Cole Moritz, Katherine Espinosa, Jeff Gelb, Sharon L. Walker, Roger M. Nisbet, Youn-Joo An, Joshua P. Schimel, Reid G. Palmer, Jose A. Hernandez-Viezcas, Lijuan Zhao, Jorge L. Gardea-Torresdey, and Patricia A. HoldenSee companion article:
- In This Issue- Sep 11, 2012
See companion article:
- Effects of manufactured nanomaterials to soybean- Nov 02, 2012
- You have accessStructural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutesVanessa Delfosse, Marina Grimaldi, Jean-Luc Pons, Abdelhay Boulahtouf, Albane le Maire, Vincent Cavailles, Gilles Labesse, William Bourguet, and Patrick Balaguer
Evolution
- You have accessArthropods in amber from the Triassic PeriodAlexander R. Schmidt, Saskia Jancke, Evert E. Lindquist, Eugenio Ragazzi, Guido Roghi, Paul C. Nascimbene, Kerstin Schmidt, Torsten Wappler, and David A. Grimaldi
- You have accessEvolution of cooperation and skew under imperfect informationErol Akçay, Adam Meirowitz, Kristopher W. Ramsay, and Simon A. Levin
- Open AccessResolving conflict in eutherian mammal phylogeny using phylogenomics and the multispecies coalescent modelSen Song, Liang Liu, Scott V. Edwards, and Shaoyuan Wu
See companion article:
- Accommodating gene tree heterogeneity- Mar 04, 2013
Genetics
- Open AccessGene balance hypothesis: Connecting issues of dosage sensitivity across biological disciplines
- Inaugural Article
James A. Birchler and Reiner A. VeitiaSee companion article:
- In This Issue- Sep 11, 2012
- Profile of James A. Birchler- Jan 23, 2013
- You have accessEndonuclease VIII-like 1 (NEIL1) promotes short-term spatial memory retention and protects from ischemic stroke-induced brain dysfunction and death in miceChandrika Canugovi, Jeong Seon Yoon, Neil H. Feldman, Deborah L. Croteau, Mark P. Mattson, and Vilhelm A. Bohr
Immunology
- Open AccessAntibodies and IL-3 support helminth-induced basophil expansionTina Herbst, Julia Esser, Moira Prati, Manuel Kulagin, Rebecca Stettler, Mario M. Zaiss, James P. Hewitson, Patrick Merky, Joseph S. Verbeek, Carole Bourquin, Mali Camberis, Melanie Prout, Rick M. Maizels, Graham Le Gros, and Nicola L. Harris
- You have accessStructural insights into the editing of germ-line–encoded interactions between T-cell receptor and MHC class II by Vα CDR3Lu Deng, Ries J. Langley, Qian Wang, Suzanne L. Topalian, and Roy A. Mariuzza
Medical Sciences
- You have accessCore circadian protein CLOCK is a positive regulator of NF-κB–mediated transcriptionMary L. Spengler, Karen K. Kuropatwinski, Maria Comas, Alexander V. Gasparian, Natalia Fedtsova, Anatoli S. Gleiberman, Ilya I. Gitlin, Natalia M. Artemicheva, Krysta A. Deluca, Andrei V. Gudkov, and Marina P. Antoch
- Open AccessFatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidismWhitney H. Brown, Matthew P. Gillum, Hui-Young Lee, Joao Paulo G. Camporez, Xian-man Zhang, Jin Kwon Jeong, Tiago C. Alves, Derek M. Erion, Blas A. Guigni, Mario Kahn, Varman T. Samuel, Benjamin F. Cravatt, Sabrina Diano, and Gerald I. Shulman
- You have accessMetabolic manifestations of insulin deficiency do not occur without glucagon actionYoung Lee, Eric D. Berglund, May-yun Wang, Xiaorong Fu, Xinxin Yu, Maureen J. Charron, Shawn C. Burgess, and Roger H. Unger
See companion article:
- In This Issue- Sep 11, 2012
- You have accessSecreted protein, acidic and rich in cysteine-like 1 (SPARCL1) is down regulated in aggressive prostate cancers and is prognostic for poor clinical outcomePaula J. Hurley, Luigi Marchionni, Brian W. Simons, Ashley E. Ross, Sarah B. Peskoe, Rebecca M. Miller, Nicholas Erho, Ismael A. Vergara, Mercedeh Ghadessi, Zhenhua Huang, Bora Gurel, Ben Ho Park, Elai Davicioni, Robert B. Jenkins, Elizabeth A. Platz, David M. Berman, and Edward M. Schaeffer
- You have accessResolvin E1 promotes phagocytosis-induced neutrophil apoptosis and accelerates resolution of pulmonary inflammationDriss El Kebir, Per Gjorstrup, and János G. Filep
Microbiology
- You have accessStructure–function analysis of pneumococcal DprA protein reveals that dimerization is crucial for loading RecA recombinase onto DNA during transformationSophie Quevillon-Cheruel, Nathalie Campo, Nicolas Mirouze, Isabelle Mortier-Barrière, Mark A. Brooks, Marion Boudes, Dominique Durand, Anne-Lise Soulet, Johnny Lisboa, Philippe Noirot, Bernard Martin, Herman van Tilbeurgh, Marie-Françoise Noirot-Gros, Jean-Pierre Claverys, and Patrice Polard
- You have accessProlonged persistence of measles virus RNA is characteristic of primary infection dynamics
- From the Cover
Wen-Hsuan W. Lin, Roger D. Kouyos, Robert J. Adams, Bryan T. Grenfell, and Diane E. GriffinSee companion article:
- Measles immunometrics- Aug 30, 2012
- You have accessInteractions between the termini of lumen enzymes and shell proteins mediate enzyme encapsulation into bacterial microcompartmentsChenguang Fan, Shouqiang Cheng, Sharmistha Sinha, and Thomas A. Bobik
- You have accessModeling early bactericidal activity in murine tuberculosis provides insights into the activity of isoniazid and pyrazinamideJacques Grosset, Deepak Almeida, Paul J. Converse, Sandeep Tyagi, Si-Yang Li, Nicole C. Ammerman, Alexander S. Pym, Kristina Wallengren, Richard Hafner, Umesh Lalloo, Susan Swindells, and William R. Bishai
Neuroscience
- You have accessNeural coding and perceptual detection in the primate somatosensory thalamusYuriria Vázquez, Antonio Zainos, Manuel Alvarez, Emilio Salinas, and Ranulfo Romo
- You have accessRetinal prosthetic strategy with the capacity to restore normal visionSheila Nirenberg and Chethan Pandarinath
- You have accessBrain conditioning is instrumental for successful microglia reconstitution following hematopoietic stem cell transplantationAlessia Capotondo, Rita Milazzo, Letterio Salvatore Politi, Angelo Quattrini, Alessio Palini, Tiziana Plati, Stefania Merella, Alessandro Nonis, Clelia di Serio, Eugenio Montini, Luigi Naldini, and Alessandra Biffi
- You have accessAutophagy activators rescue and alleviate pathogenesis of a mouse model with proteinopathies of the TAR DNA-binding protein 43I-Fang Wang, Bo-Shen Guo, Yu-Chih Liu, Cheng-Chun Wu, Chun-Hung Yang, Kuen-Jer Tsai, and Che-Kun James Shen
Pharmacology
- You have accessDiscovery and validation of small-molecule heat-shock protein 90 inhibitors through multimodality molecular imaging in living subjectsCarmel T. Chan, Robert E. Reeves, Ron Geller, Shahriar S. Yaghoubi, Aileen Hoehne, David E. Solow-Cordero, Gabriela Chiosis, Tarik F. Massoud, Ramasamy Paulmurugan, and Sanjiv S. Gambhir
- You have accessPutative DNA/RNA helicase Schlafen-11 (SLFN11) sensitizes cancer cells to DNA-damaging agentsGabriele Zoppoli, Marie Regairaz, Elisabetta Leo, William C. Reinhold, Sudhir Varma, Alberto Ballestrero, James H. Doroshow, and Yves Pommier
Physiology
- You have accessMouse lipin-1 and lipin-2 cooperate to maintain glycerolipid homeostasis in liver and aging cerebellumJennifer R. Dwyer, Jimmy Donkor, Peixiang Zhang, Lauren S. Csaki, Laurent Vergnes, Jessica M. Lee, Jay Dewald, David N. Brindley, Elisa Atti, Sotirios Tetradis, Yuko Yoshinaga, Pieter J. De Jong, Loren G. Fong, Stephen G. Young, and Karen Reue
- Open AccessHuman blood metabolite timetable indicates internal body timeTakeya Kasukawa, Masahiro Sugimoto, Akiko Hida, Yoichi Minami, Masayo Mori, Sato Honma, Ken-ichi Honma, Kazuo Mishima, Tomoyoshi Soga, and Hiroki R. Ueda
- You have accessThe nerve of ovulation-inducing factor in semenMarcelo H. Ratto, Yvonne A. Leduc, Ximena P. Valderrama, Karin E. van Straaten, Louis T. J. Delbaere, Roger A. Pierson, and Gregg P. Adams
- Open AccessRegulation of beta catenin signaling and parathyroid hormone anabolic effects in bone by the matricellular protein periostinNicolas Bonnet, Simon J. Conway, and Serge L. Ferrari
Plant Biology
- Open AccessPhotoperiodic regulation of the C-repeat binding factor (CBF) cold acclimation pathway and freezing tolerance in Arabidopsis thalianaChin-Mei Lee and Michael F. Thomashow
- Open AccessRegulation of planar growth by the Arabidopsis AGC protein kinase UNICORNBalaji Enugutti, Charlotte Kirchhelle, Maxi Oelschner, Ramón Angel Torres Ruiz, Ivo Schliebner, Dario Leister, and Kay Schneitz
Population Biology
- Open AccessHigh genetic load in an old isolated butterfly populationAnniina L. K. Mattila, Anne Duplouy, Malla Kirjokangas, Rainer Lehtonen, Pasi Rastas, and Ilkka Hanski
- You have accessUnifying the spatial epidemiology and molecular evolution of emerging epidemicsOliver G. Pybus, Marc A. Suchard, Philippe Lemey, Flavien J. Bernardin, Andrew Rambaut, Forrest W. Crawford, Rebecca R. Gray, Nimalan Arinaminpathy, Susan L. Stramer, Michael P. Busch, and Eric L. Delwart
Commentaries
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