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Research Article
Experimental viral evolution to specific host MHC genotypes reveals fitness and virulence trade-offs in alternative MHC types
Jason L. Kubinak, James S. Ruff, Cornelius Whitney Hyzer, Patricia R. Slev, and Wayne K. Potts
Jason L. Kubinak
James S. Ruff
Cornelius Whitney Hyzer
Patricia R. Slev
Edited by Michael Lynch, Indiana University, Bloomington, IN, and approved January 17, 2012 (received for review August 4, 2011)

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Article Information
vol. 109 no. 9 3422-3427
PubMed:
Published By:
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Online ISSN:
History:
- Published in issue February 28, 2012.
- Published first February 7, 2012.
Author Information
Footnotes
- ↵1To whom correspondence should be addressed. E-mail: jason.kubinak{at}path.utah.edu.
Author contributions: J.L.K., J.S.R., P.R.S., and W.K.P. designed research; J.L.K. and C.W.H. performed research; J.L.K. and W.K.P. analyzed data; and J.L.K. and W.K.P. wrote the manuscript.
The authors declare no conflict of interest.
This article is a PNAS Direct Submission.
This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1112633109/-/DCSupplemental.
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Article usage
Experimental viral evolution to specific host MHC genotypes reveals fitness and virulence trade-offs in alternative MHC types
Jason L. Kubinak, James S. Ruff, Cornelius Whitney Hyzer, Patricia R. Slev, Wayne K. Potts
Proceedings of the National Academy of Sciences Feb 2012, 109 (9) 3422-3427; DOI: 10.1073/pnas.1112633109
Citation Manager Formats
Experimental viral evolution to specific host MHC genotypes reveals fitness and virulence trade-offs in alternative MHC types
Jason L. Kubinak, James S. Ruff, Cornelius Whitney Hyzer, Patricia R. Slev, Wayne K. Potts
Proceedings of the National Academy of Sciences Feb 2012, 109 (9) 3422-3427; DOI: 10.1073/pnas.1112633109
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