Table of Contents

Biological Sciences

• Agricultural Sciences

  • Open Access

    Mutation in CSA creates a new photoperiod-sensitive genic male sterile line applicable for hybrid rice seed production

    Hui Zhang, Chenxi Xu, Yi He, Jie Zong, Xijia Yang, Huamin Si, Zongxiu Sun, Jianping Hu, Wanqi Liang, and Dabing Zhang

    PNAS January 2, 2013 110 (1) 76-81; first published December 19, 2012. https://doi.org/10.1073/pnas.1213041110

• Applied Biological Sciences

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    Production of unique immunotoxin cancer therapeutics in algal chloroplasts

    Miller Tran, Christina Van, Daniel J. Barrera, Pär L. Pettersson, Carlos D. Peinado, Jack Bui, and Stephen P. Mayfield

    PNAS January 2, 2013 110 (1) E15-E22; first published December 10, 2012. https://doi.org/10.1073/pnas.1214638110
  • Open Access

    pH (low) insertion peptide (pHLIP) targets ischemic myocardium

    Eugene A. Sosunov, Evgeny P. Anyukhovsky, Alexander A. Sosunov, Anna Moshnikova, Dayanjali Wijesinghe, Donald M. Engelman, Yana K. Reshetnyak, and Oleg A. Andreev

    PNAS January 2, 2013 110 (1) 82-86; first published December 17, 2012. https://doi.org/10.1073/pnas.1220038110
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    Carboxylic acid reductase is a versatile enzyme for the conversion of fatty acids into fuels and chemical commodities

    M. Kalim Akhtar, Nicholas J. Turner, and Patrik R. Jones

    PNAS January 2, 2013 110 (1) 87-92; first published December 17, 2012. https://doi.org/10.1073/pnas.1216516110
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    Imaging a functional tumorigenic biomarker in the transformed epithelium

    Aaron M. LeBeau, Minhee Lee, Stephanie T. Murphy, Byron C. Hann, Robert S. Warren, Romelyn Delos Santos, John Kurhanewicz, Samir M. Hanash, Henry F. VanBrocklin, and Charles S. Craik

    PNAS January 2, 2013 110 (1) 93-98; first published December 17, 2012. https://doi.org/10.1073/pnas.1218694110

• Biochemistry

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    Regulation of the actin-activated MgATPase activity of Acanthamoeba myosin II by phosphorylation of serine 639 in motor domain loop 2

    Xiong Liu, Duck-Yeon Lee, Shutao Cai, Shuhua Yu, Shi Shu, Rodney L. Levine, and Edward D. Korn

    PNAS January 2, 2013 110 (1) E23-E32; first published December 17, 2012. https://doi.org/10.1073/pnas.1219713110

    See companion article:

    • PNAS Plus Significance Statements

      - Jan 02, 2013
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    Regulation of the filament structure and assembly of Acanthamoeba myosin II by phosphorylation of serines in the heavy-chain nonhelical tailpiece

    Xiong Liu, Myoung-Soon Hong, Shi Shu, Shuhua Yu, and Edward D. Korn

    PNAS January 2, 2013 110 (1) E33-E40; first published December 17, 2012. https://doi.org/10.1073/pnas.1219727110

    See companion article:

    • PNAS Plus Significance Statements

      - Jan 02, 2013
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    A Pictet-Spengler ligation for protein chemical modification

    Paresh Agarwal, Joep van der Weijden, Ellen M. Sletten, David Rabuka, and Carolyn R. Bertozzi

    PNAS January 2, 2013 110 (1) 46-51; first published December 13, 2012. https://doi.org/10.1073/pnas.1213186110
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    How a holoenzyme for DNA replication is formed

    Senthil K. Perumal, Wenhui Ren, Tae-Hee Lee, and Stephen J. Benkovic

    PNAS January 2, 2013 110 (1) 99-104; first published December 17, 2012. https://doi.org/10.1073/pnas.1212748110
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    CpG underrepresentation and the bacterial CpG-specific DNA methyltransferase M.MpeI

    Marek Wojciechowski, Honorata Czapinska, and Matthias Bochtler

    PNAS January 2, 2013 110 (1) 105-110; first published December 17, 2012. https://doi.org/10.1073/pnas.1207986110
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    Ras GTPase activating (RasGAP) activity of the dual specificity GAP protein Rasal requires colocalization and C2 domain binding to lipid membranes

    Begoña Sot, Elmar Behrmann, Stefan Raunser, and Alfred Wittinghofer

    PNAS January 2, 2013 110 (1) 111-116; first published December 18, 2012. https://doi.org/10.1073/pnas.1201658110
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    Regulation of SIK1 abundance and stability is critical for myogenesis

    Randi Stewart, Dmitry Akhmedov, Christopher Robb, Courtney Leiter, and Rebecca Berdeaux

    PNAS January 2, 2013 110 (1) 117-122; first published December 19, 2012. https://doi.org/10.1073/pnas.1212676110

• Biophysics and Computational Biology

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    NMR imaging of cell phone radiation absorption in brain tissue

    David H. Gultekin and Lothar Moeller

    PNAS January 2, 2013 110 (1) 58-63; first published December 17, 2012. https://doi.org/10.1073/pnas.1205598109

    See companion article:

    • In This Issue

      - Jan 02, 2013
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    Antibacterial drug leads targeting isoprenoid biosynthesis

    Wei Zhu, Yonghui Zhang, William Sinko, Mary E. Hensler, Joshua Olson, Katie J. Molohon, Steffen Lindert, Rong Cao, Kai Li, Ke Wang, Yang Wang, Yi-Liang Liu, Anna Sankovsky, César Augusto F. de Oliveira, Douglas A. Mitchell, Victor Nizet, J. Andrew McCammon, and Eric Oldfield

    PNAS January 2, 2013 110 (1) 123-128; first published December 17, 2012. https://doi.org/10.1073/pnas.1219899110
  • Open Access

    Migration of cells in a social context

    Søren Vedel, Savaş Tay, Darius M. Johnston, Henrik Bruus, and Stephen R. Quake

    PNAS January 2, 2013 110 (1) 129-134; first published December 18, 2012. https://doi.org/10.1073/pnas.1204291110
  • Open Access

    Millisecond spatiotemporal dynamics of FRET biosensors by the pair correlation function and the phasor approach to FLIM

    Elizabeth Hinde, Michelle A. Digman, Klaus M. Hahn, and Enrico Gratton

    PNAS January 2, 2013 110 (1) 135-140; first published December 17, 2012. https://doi.org/10.1073/pnas.1211882110
  • Open Access

    Pharmaceutically controlled designer circuit for the treatment of the metabolic syndrome

    Haifeng Ye, Ghislaine Charpin-El Hamri, Katharina Zwicky, Matthias Christen, Marc Folcher, and Martin Fussenegger

    PNAS January 2, 2013 110 (1) 141-146; first published December 17, 2012. https://doi.org/10.1073/pnas.1216801110
  • Open Access

    Golden triangle for folding rates of globular proteins

    Sergiy O. Garbuzynskiy, Dmitry N. Ivankov, Natalya S. Bogatyreva, and Alexei V. Finkelstein

    PNAS January 2, 2013 110 (1) 147-150; first published December 18, 2012. https://doi.org/10.1073/pnas.1210180110
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    ATP-independent diffusion of double-stranded RNA binding proteins

    Hye Ran Koh, Mary Anne Kidwell, Kaushik Ragunathan, Jennifer A. Doudna, and Sua Myong

    PNAS January 2, 2013 110 (1) 151-156; first published December 18, 2012. https://doi.org/10.1073/pnas.1212917110

• Cell Biology

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    DNA damage checkpoint triggers autophagy to regulate the initiation of anaphase

    Farokh Dotiwala, Vinay V. Eapen, Jacob C. Harrison, Ayelet Arbel-Eden, Vikram Ranade, Satoshi Yoshida, and James E. Haber

    PNAS January 2, 2013 110 (1) E41-E49; first published November 19, 2012. https://doi.org/10.1073/pnas.1218065109
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    Long-lived microRNA–Argonaute complexes in quiescent cells can be activated to regulate mitogenic responses

    Scott H. Olejniczak, Gaspare La Rocca, Joshua J. Gruber, and Craig B. Thompson

    PNAS January 2, 2013 110 (1) 157-162; first published December 17, 2012. https://doi.org/10.1073/pnas.1219958110
  • Open Access

    Rotational motion during three-dimensional morphogenesis of mammary epithelial acini relates to laminin matrix assembly

    Hui Wang, Sam Lacoche, Ling Huang, Bin Xue, and Senthil K. Muthuswamy

    PNAS January 2, 2013 110 (1) 163-168; first published December 17, 2012. https://doi.org/10.1073/pnas.1201141110
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    Disassembly of synthetic Agrobacterium T-DNA–protein complexes via the host SCF^VBF ubiquitin–ligase complex pathway

    Adi Zaltsman, Benoît Lacroix, Yedidya Gafni, and Vitaly Citovsky

    PNAS January 2, 2013 110 (1) 169-174; first published December 17, 2012. https://doi.org/10.1073/pnas.1210921110
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    Spatiotemporal analysis of organelle and macromolecular complex inheritance

    Victoria Menendez-Benito, Sjoerd J. van Deventer, Victor Jimenez-Garcia, Marina Roy-Luzarraga, Fred van Leeuwen, and Jacques Neefjes

    PNAS January 2, 2013 110 (1) 175-180; first published December 17, 2012. https://doi.org/10.1073/pnas.1207424110
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    Cell-type–specific roles of Na⁺/K⁺ ATPase subunits in Drosophila auditory mechanosensation

    • From the Cover

    Madhuparna Roy, Elena Sivan-Loukianova, and Daniel F. Eberl

    PNAS January 2, 2013 110 (1) 181-186; first published December 17, 2012. https://doi.org/10.1073/pnas.1208866110

• Developmental Biology

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    Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family

    Enzo R. Porrello, Ahmed I. Mahmoud, Emma Simpson, Brett A. Johnson, David Grinsfelder, Diana Canseco, Pradeep P. Mammen, Beverly A. Rothermel, Eric N. Olson, and Hesham A. Sadek

    PNAS January 2, 2013 110 (1) 187-192; first published December 17, 2012. https://doi.org/10.1073/pnas.1208863110
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    Stable transgenesis in the marine annelid Platynereis dumerilii sheds new light on photoreceptor evolution

    Benjamin Backfisch, Vinoth Babu Veedin Rajan, Ruth M. Fischer, Claudia Lohs, Enrique Arboleda, Kristin Tessmar-Raible, and Florian Raible

    PNAS January 2, 2013 110 (1) 193-198; first published January 2, 2013. https://doi.org/10.1073/pnas.1209657109

• Ecology

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    Exposure of Solidago altissima plants to volatile emissions of an insect antagonist (Eurosta solidaginis) deters subsequent herbivory

    Anjel M. Helms, Consuelo M. De Moraes, John F. Tooker, and Mark C. Mescher

    PNAS January 2, 2013 110 (1) 199-204; first published December 13, 2012. https://doi.org/10.1073/pnas.1218606110
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    Resonance-induced multimodal body-size distributions in ecosystems

    Adam Lampert and Tsvi Tlusty

    PNAS January 2, 2013 110 (1) 205-209; first published December 17, 2012. https://doi.org/10.1073/pnas.1211761110

• Environmental Sciences

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    Response of vegetation to drought time-scales across global land biomes

    Sergio M. Vicente-Serrano, Célia Gouveia, Jesús Julio Camarero, Santiago Beguería, Ricardo Trigo, Juan I. López-Moreno, César Azorín-Molina, Edmond Pasho, Jorge Lorenzo-Lacruz, Jesús Revuelto, Enrique Morán-Tejeda, and Arturo Sanchez-Lorenzo

    PNAS January 2, 2013 110 (1) 52-57; first published December 17, 2012. https://doi.org/10.1073/pnas.1207068110
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    Chytrid fungus Batrachochytrium dendrobatidis has nonamphibian hosts and releases chemicals that cause pathology in the absence of infection

    Taegan A. McMahon, Laura A. Brannelly, Matthew W. H. Chatfield, Pieter T. J. Johnson, Maxwell B. Joseph, Valerie J. McKenzie, Corinne L. Richards-Zawacki, Matthew D. Venesky, and Jason R. Rohr

    PNAS January 2, 2013 110 (1) 210-215; first published December 17, 2012. https://doi.org/10.1073/pnas.1200592110

• Evolution

  • Open Access

    Prosocial preferences do not explain human cooperation in public-goods games

    Maxwell N. Burton-Chellew and Stuart A. West

    PNAS January 2, 2013 110 (1) 216-221; first published December 17, 2012. https://doi.org/10.1073/pnas.1210960110
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    Mutation rate dynamics in a bacterial population reflect tension between adaptation and genetic load

    Sébastien Wielgoss, Jeffrey E. Barrick, Olivier Tenaillon, Michael J. Wiser, W. James Dittmar, Stéphane Cruveiller, Béatrice Chane-Woon-Ming, Claudine Médigue, Richard E. Lenski, and Dominique Schneider

    PNAS January 2, 2013 110 (1) 222-227; first published December 17, 2012. https://doi.org/10.1073/pnas.1219574110
  • Open Access

    Birth–death skyline plot reveals temporal changes of epidemic spread in HIV and hepatitis C virus (HCV)

    Tanja Stadler, Denise Kühnert, Sebastian Bonhoeffer, and Alexei J. Drummond

    PNAS January 2, 2013 110 (1) 228-233; first published December 17, 2012. https://doi.org/10.1073/pnas.1207965110

• Genetics

  • Open Access

    Functional characterization of piggyBat from the bat Myotis lucifugus unveils an active mammalian DNA transposon

    Rupak Mitra, Xianghong Li, Aurélie Kapusta, David Mayhew, Robi D. Mitra, Cédric Feschotte, and Nancy L. Craig

    PNAS January 2, 2013 110 (1) 234-239; first published December 17, 2012. https://doi.org/10.1073/pnas.1217548110
  • Open Access

    Genetic loci associated with delayed clearance of Plasmodium falciparum following artemisinin treatment in Southeast Asia

    Shannon Takala-Harrison, Taane G. Clark, Christopher G. Jacob, Michael P. Cummings, Olivo Miotto, Arjen M. Dondorp, Mark M. Fukuda, Francois Nosten, Harald Noedl, Mallika Imwong, Delia Bethell, Youry Se, Chanthap Lon, Stuart D. Tyner, David L. Saunders, Duong Socheat, Frederic Ariey, Aung Pyae Phyo, Peter Starzengruber, Hans-Peter Fuehrer, Paul Swoboda, Kasia Stepniewska, Jennifer Flegg, Cesar Arze, Gustavo C. Cerqueira, Joana C. Silva, Stacy M. Ricklefs, Stephen F. Porcella, Robert M. Stephens, Matthew Adams, Leo J. Kenefic, Susana Campino, Sarah Auburn, Bronwyn MacInnis, Dominic P. Kwiatkowski, Xin-zhuan Su, Nicholas J. White, Pascal Ringwald, and Christopher V. Plowe

    PNAS January 2, 2013 110 (1) 240-245; first published December 17, 2012. https://doi.org/10.1073/pnas.1211205110
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    Proteasome inhibition rescues clinically significant unstable variants of the mismatch repair protein Msh2

    Tim Arlow, Kristan Scott, Aubrey Wagenseller, and Alison Gammie

    PNAS January 2, 2013 110 (1) 246-251; first published December 17, 2012. https://doi.org/10.1073/pnas.1215510110
  • Open Access

    Directionally selected cytochrome P450 alleles are driving the spread of pyrethroid resistance in the major malaria vector Anopheles funestus

    • From the Cover

    Jacob M. Riveron, Helen Irving, Miranda Ndula, Kayla G. Barnes, Sulaiman S. Ibrahim, Mark J. I. Paine, and Charles S. Wondji

    PNAS January 2, 2013 110 (1) 252-257; first published December 17, 2012. https://doi.org/10.1073/pnas.1216705110

    See companion article:

    • In This Issue

      - Jan 02, 2013
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    Rho-dependent transcription termination is essential to prevent excessive genome-wide R-loops in Escherichia coli

    J. Krishna Leela, Aisha H. Syeda, K. Anupama, and J. Gowrishankar

    PNAS January 2, 2013 110 (1) 258-263; first published December 18, 2012. https://doi.org/10.1073/pnas.1213123110

• Immunology

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    Interferon-γ mediates chemokine-dependent recruitment of natural killer cells during viral infection

    Melissa A. Pak-Wittel, Liping Yang, Dorothy K. Sojka, Joshua G. Rivenbark, and Wayne M. Yokoyama

    PNAS January 2, 2013 110 (1) E50-E59; first published December 17, 2012. https://doi.org/10.1073/pnas.1220456110

    See companion article:

    • PNAS Plus Significance Statements

      - Jan 02, 2013
  • Open Access

    Engineering antigens for in situ erythrocyte binding induces T-cell deletion

    Stephan Kontos, Iraklis C. Kourtis, Karen Y. Dane, and Jeffrey A. Hubbell

    PNAS January 2, 2013 110 (1) E60-E68; first published December 17, 2012. https://doi.org/10.1073/pnas.1216353110
  • Open Access

    Preconfiguration of the antigen-binding site during affinity maturation of a broadly neutralizing influenza virus antibody

    • From the Cover

    Aaron G. Schmidt, Huafeng Xu, Amir R. Khan, Timothy O’Donnell, Surender Khurana, Lisa R. King, Jody Manischewitz, Hana Golding, Pirada Suphaphiphat, Andrea Carfi, Ethan C. Settembre, Philip R. Dormitzer, Thomas B. Kepler, Ruijun Zhang, M. Anthony Moody, Barton F. Haynes, Hua-Xin Liao, David E. Shaw, and Stephen C. Harrison

    PNAS January 2, 2013 110 (1) 264-269; first published November 21, 2012. https://doi.org/10.1073/pnas.1218256109

    See companion article:

    • Immunopaleontology reveals how affinity enhancement is achieved during affinity maturation of antibodies to influenza virus

      - Jan 02, 2013
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    Systemic administration of a bispecific antibody targeting EGFRvIII successfully treats intracerebral glioma

    Bryan D. Choi, Chien-Tsun Kuan, Mingqing Cai, Gary E. Archer, Duane A. Mitchell, Patrick C. Gedeon, Luis Sanchez-Perez, Ira Pastan, Darell D. Bigner, and John H. Sampson

    PNAS January 2, 2013 110 (1) 270-275; first published December 17, 2012. https://doi.org/10.1073/pnas.1219817110
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    Transcription factor YY1 is essential for regulation of the Th2 cytokine locus and for Th2 cell differentiation

    Soo Seok Hwang, Young Uk Kim, Sumin Lee, Sung Woong Jang, Min Kyung Kim, Byung Hee Koh, Wonyong Lee, Joomyeong Kim, Abdallah Souabni, Meinrad Busslinger, and Gap Ryol Lee

    PNAS January 2, 2013 110 (1) 276-281; first published December 17, 2012. https://doi.org/10.1073/pnas.1214682110
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    IL-33 drives biphasic IL-13 production for noncanonical Type 2 immunity against hookworms

    Li-Yin Hung, Ian P. Lewkowich, Lucas A. Dawson, Jordan Downey, Yanfen Yang, Dirk E. Smith, and De'Broski R. Herbert

    PNAS January 2, 2013 110 (1) 282-287; first published December 17, 2012. https://doi.org/10.1073/pnas.1206587110
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    Viral antigen density and confinement time regulate the reactivity pattern of CD4 T-cell responses to vaccinia virus infection

    Vijay Vanguri, Christopher C. Govern, Rebecca Smith, and Eric S. Huseby

    PNAS January 2, 2013 110 (1) 288-293; first published December 17, 2012. https://doi.org/10.1073/pnas.1208328110
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    Murine Guanylate Binding Protein 2 (mGBP2) controls Toxoplasma gondii replication

    Daniel Degrandi, Elisabeth Kravets, Carolin Konermann, Cornelia Beuter-Gunia, Verena Klümpers, Sarah Lahme, Eva Wischmann, Anne K. Mausberg, Sandra Beer-Hammer, and Klaus Pfeffer

    PNAS January 2, 2013 110 (1) 294-299; first published December 17, 2012. https://doi.org/10.1073/pnas.1205635110

• Medical Sciences

  • Open Access

    Diverse specificity and effector function among human antibodies to HIV-1 envelope glycoprotein epitopes exposed by CD4 binding

    Yongjun Guan, Marzena Pazgier, Mohammad M. Sajadi, Roberta Kamin-Lewis, Salma Al-Darmarki, Robin Flinko, Elena Lovo, Xueji Wu, James E. Robinson, Michael S. Seaman, Timothy R. Fouts, Robert C. Gallo, Anthony L. DeVico, and George K. Lewis

    PNAS January 2, 2013 110 (1) E69-E78; first published December 13, 2012. https://doi.org/10.1073/pnas.1217609110
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    Nonreceptor tyrosine phosphatase Shp2 promotes adipogenesis through inhibition of p38 MAP kinase

    Zhao He, Helen H. Zhu, Timothy J. Bauler, Jing Wang, Theodore Ciaraldi, Nazilla Alderson, Shuangwei Li, Marie-Astrid Raquil, Kaihong Ji, Shufen Wang, Jianhua Shao, Robert R. Henry, Philip D. King, and Gen-Sheng Feng

    PNAS January 2, 2013 110 (1) E79-E88; first published December 10, 2012. https://doi.org/10.1073/pnas.1213000110
  • Open Access

    p53 cooperates with DNA methylation and a suicidal interferon response to maintain epigenetic silencing of repeats and noncoding RNAs

    Katerina I. Leonova, Leonid Brodsky, Brittany Lipchick, Mahadeb Pal, Liliya Novototskaya, Alex A. Chenchik, Ganes C. Sen, Elena A. Komarova, and Andrei V. Gudkov

    PNAS January 2, 2013 110 (1) E89-E98; first published December 10, 2012. https://doi.org/10.1073/pnas.1216922110
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    Disrupted and transgenic urate oxidase alter urate and dopaminergic neurodegeneration

    Xiqun Chen, Thomas C. Burdett, Cody A. Desjardins, Robert Logan, Sara Cipriani, Yuehang Xu, and Michael A. Schwarzschild

    PNAS January 2, 2013 110 (1) 300-305; first published December 17, 2012. https://doi.org/10.1073/pnas.1217296110
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    Endothelial glucocorticoid receptor is required for protection against sepsis

    Julie E. Goodwin, Yan Feng, Heino Velazquez, and William C. Sessa

    PNAS January 2, 2013 110 (1) 306-311; first published December 17, 2012. https://doi.org/10.1073/pnas.1210200110
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    N terminus of ASPP2 binds to Ras and enhances Ras/Raf/MEK/ERK activation to promote oncogene-induced senescence

    Zhiping Wang, Yuangang Liu, Maho Takahashi, Kathryn Van Hook, Kerstin M. Kampa-Schittenhelm, Brett C. Sheppard, Rosalie C. Sears, Philip J. S. Stork, and Charles D. Lopez

    PNAS January 2, 2013 110 (1) 312-317; first published December 17, 2012. https://doi.org/10.1073/pnas.1201514110
  • Open Access

    Atomic model of the human cardiac muscle myosin filament

    Hind A. AL-Khayat, Robert W. Kensler, John M. Squire, Steven B. Marston, and Edward P. Morris

    PNAS January 2, 2013 110 (1) 318-323; first published December 18, 2012. https://doi.org/10.1073/pnas.1212708110

• Microbiology

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    Accurate prediction of secondary metabolite gene clusters in filamentous fungi

    Mikael R. Andersen, Jakob B. Nielsen, Andreas Klitgaard, Lene M. Petersen, Mia Zachariasen, Tilde J. Hansen, Lene H. Blicher, Charlotte H. Gotfredsen, Thomas O. Larsen, Kristian F. Nielsen, and Uffe H. Mortensen

    PNAS January 2, 2013 110 (1) E99-E107; first published December 17, 2012. https://doi.org/10.1073/pnas.1205532110
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    A ribosome-specialized translation initiation pathway is required for cap-dependent translation of vesicular stomatitis virus mRNAs

    • From the Cover

    Amy Si-Ying Lee, Rebeca Burdeinick-Kerr, and Sean P. J. Whelan

    PNAS January 2, 2013 110 (1) 324-329; first published November 19, 2012. https://doi.org/10.1073/pnas.1216454109

    See companion article:

    • Ribosomes take control

      - Jan 02, 2013
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    Evidence for hydrogen oxidation and metabolic plasticity in widespread deep-sea sulfur-oxidizing bacteria

    Karthik Anantharaman, John A. Breier, Cody S. Sheik, and Gregory J. Dick

    PNAS January 2, 2013 110 (1) 330-335; first published December 20, 2012. https://doi.org/10.1073/pnas.1215340110

• Neuroscience

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    MDGAs interact selectively with neuroligin-2 but not other neuroligins to regulate inhibitory synapse development

    Kangduk Lee, Yoonji Kim, Sung-Jin Lee, Yuan Qiang, Dongmin Lee, Hyun Woo Lee, Hyun Kim, H. Shawn Je, Thomas C. Südhof, and Jaewon Ko

    PNAS January 2, 2013 110 (1) 336-341; first published December 17, 2012. https://doi.org/10.1073/pnas.1219987110
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    Pathway-specific modulation of nucleus accumbens in reward and aversive behavior via selective transmitter receptors

    Takatoshi Hikida, Satoshi Yawata, Takashi Yamaguchi, Teruko Danjo, Toshikuni Sasaoka, Yanyan Wang, and Shigetada Nakanishi

    PNAS January 2, 2013 110 (1) 342-347; first published December 17, 2012. https://doi.org/10.1073/pnas.1220358110
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    Activation of 5-HT2A receptors upregulates the function of the neuronal K-Cl cotransporter KCC2

    Rémi Bos, Karina Sadlaoud, Pascale Boulenguez, Dorothée Buttigieg, Sylvie Liabeuf, Cécile Brocard, Georg Haase, Hélène Bras, and Laurent Vinay

    PNAS January 2, 2013 110 (1) 348-353; first published December 17, 2012. https://doi.org/10.1073/pnas.1213680110
  • Open Access

    Repair of the degenerate retina by photoreceptor transplantation

    Amanda C. Barber, Claire Hippert, Yanai Duran, Emma L. West, James W. B. Bainbridge, Katherine Warre-Cornish, Ulrich F. O. Luhmann, Jorn Lakowski, Jane C. Sowden, Robin R. Ali, and Rachael A. Pearson

    PNAS January 2, 2013 110 (1) 354-359; first published December 17, 2012. https://doi.org/10.1073/pnas.1212677110

    See companion article:

    • In This Issue

      - Jan 02, 2013

• Physiology

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    Dynamic modulation of ANO1/TMEM16A HCO₃⁻ permeability by Ca²⁺/calmodulin

    Jinsei Jung, Joo Hyun Nam, Hyun Woo Park, Uhtaek Oh, Joo-Heon Yoon, and Min Goo Lee

    PNAS January 2, 2013 110 (1) 360-365; first published December 17, 2012. https://doi.org/10.1073/pnas.1211594110

• Plant Biology

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    Evolutionarily conserved repressive activity of WOX proteins mediates leaf blade outgrowth and floral organ development in plants

    Hao Lin, Lifang Niu, Neil A. McHale, Masaru Ohme-Takagi, Kirankumar S. Mysore, and Million Tadege

    PNAS January 2, 2013 110 (1) 366-371; first published December 17, 2012. https://doi.org/10.1073/pnas.1215376110

• Sustainability Science

  • Open Access

    Joint analysis of stressors and ecosystem services to enhance restoration effectiveness

    J. David Allan, Peter B. McIntyre, Sigrid D. P. Smith, Benjamin S. Halpern, Gregory L. Boyer, Andy Buchsbaum, G. A. Burton Jr., Linda M. Campbell, W. Lindsay Chadderton, Jan J. H. Ciborowski, Patrick J. Doran, Tim Eder, Dana M. Infante, Lucinda B. Johnson, Christine A. Joseph, Adrienne L. Marino, Alexander Prusevich, Jennifer G. Read, Joan B. Rose, Edward S. Rutherford, Scott P. Sowa, and Alan D. Steinman

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• Systems Biology

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