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Table of Contents
March 05, 2013; vol. 110 no. 10
This Week in PNAS
Letters (Online Only)
- You have accessReply to Massey: Drift does influence mutation-rate evolutionWay Sung, Matthew S. Ackerman, Samuel F. Miller, Thomas G. Doak, and Michael Lynch
News Feature
Science and Culture
Retrospective
- You have accessElwood V. Jensen (1920–2012): Father of the nuclear receptorsBert W. O’Malley and Sohaib Khan
Inner Workings
Core Concepts
PNAS Plus Significance Statements
Physical Sciences
Applied Mathematics
- You have accessPhenotypic model for early T-cell activation displaying sensitivity, specificity, and antagonismPaul François, Guillaume Voisinne, Eric D. Siggia, Grégoire Altan-Bonnet, and Massimo Vergassola
- You have accessModeling shows that the NS5A inhibitor daclatasvir has two modes of action and yields a shorter estimate of the hepatitis C virus half-lifeJeremie Guedj, Harel Dahari, Libin Rong, Natasha D. Sansone, Richard E. Nettles, Scott J. Cotler, Thomas J. Layden, Susan L. Uprichard, and Alan S. Perelson
Applied Physical Sciences
- You have accessSurface layering and melting in an ionic liquid studied by resonant soft X-ray reflectivityMarkus Mezger, Benjamin M. Ocko, Harald Reichert, and Moshe Deutsch
- You have accessCoupling the valley degree of freedom to antiferromagnetic orderXiao Li, Ting Cao, Qian Niu, Junren Shi, and Ji Feng
Chemistry
- You have accessInsights into antiamyloidogenic properties of the green tea extract (−)-epigallocatechin-3-gallate toward metal-associated amyloid-β speciesSuk-Joon Hyung, Alaina S. DeToma, Jeffrey R. Brender, Sanghyun Lee, Subramanian Vivekanandan, Akiko Kochi, Jung-Suk Choi, Ayyalusamy Ramamoorthy, Brandon T. Ruotolo, and Mi Hee Lim
- You have accessSynthesis of an extra-large molecular sieve using proton sponges as organic structure-directing agentsRaquel Martínez-Franco, Manuel Moliner, Yifeng Yun, Junliang Sun, Wei Wan, Xiaodong Zou, and Avelino Corma
- You have accessElasticity, structure, and relaxation of extended proteins under forceGuillaume Stirnemann, David Giganti, Julio M. Fernandez, and B. J. Berne
Earth, Atmospheric, and Planetary Sciences
- Open AccessReal-time 3D imaging of Haines jumps in porous media flowSteffen Berg, Holger Ott, Stephan A. Klapp, Alex Schwing, Rob Neiteler, Niels Brussee, Axel Makurat, Leon Leu, Frieder Enzmann, Jens-Oliver Schwarz, Michael Kersten, Sarah Irvine, and Marco Stampanoni
- You have accessWorldwide data sets constrain the water vapor uptake coefficient in cloud formationTomi Raatikainen, Athanasios Nenes, John H. Seinfeld, Ricardo Morales, Richard H. Moore, Terry L. Lathem, Sara Lance, Luz T. Padró, Jack J. Lin, Kate M. Cerully, Aikaterini Bougiatioti, Julie Cozic, Christopher R. Ruehl, Patrick Y. Chuang, Bruce E. Anderson, Richard C. Flagan, Haflidi Jonsson, Nikos Mihalopoulos, and James N. Smith
Environmental Sciences
- Open AccessProteomic analysis of skeletal organic matrix from the stony coral Stylophora pistillataJeana L. Drake, Tali Mass, Liti Haramaty, Ehud Zelzion, Debashish Bhattacharya, and Paul G. Falkowski
- You have accessThe steady-state mosaic of disturbance and succession across an old-growth Central Amazon forest landscape
- From the Cover
Jeffrey Q. Chambers, Robinson I. Negron-Juarez, Daniel Magnabosco Marra, Alan Di Vittorio, Joerg Tews, Dar Roberts, Gabriel H. P. M. Ribeiro, Susan E. Trumbore, and Niro Higuchi
Physics
- You have accessExperimental demonstration of radicaloid character in a RuV=O intermediate in catalytic water oxidationDooshaye Moonshiram, Igor Alperovich, Javier J. Concepcion, Thomas J. Meyer, and Yulia Pushkar
- You have accessRelation between ordering and shear thinning in colloidal suspensionsXinliang Xu, Stuart A. Rice, and Aaron R. Dinner
- Open AccessOpening up three quantum boxes causes classically undetectable wavefunction collapseRichard E. George, Lucio M. Robledo, Owen J. E. Maroney, Machiel S. Blok, Hannes Bernien, Matthew L. Markham, Daniel J. Twitchen, John J. L. Morton, G. Andrew D. Briggs, and Ronald Hanson
- You have accessActin cytoskeleton of chemotactic amoebae operates close to the onset of oscillationsChristian Westendorf, Jose Negrete Jr., Albert J. Bae, Rabea Sandmann, Eberhard Bodenschatz, and Carsten Beta
Social Sciences
Economic Sciences
- You have accessVariants at serotonin transporter and 2A receptor genes predict cooperative behavior differentially according to presence of punishmentKari B. Schroeder, Richard McElreath, and Daniel Nettle
Biological Sciences
Applied Biological Sciences
- You have accessDirect production of mouse disease models by embryo microinjection of TALENs and oligodeoxynucleotidesBenedikt Wefers, Melanie Meyer, Oskar Ortiz, Martin Hrabé de Angelis, Jens Hansen, Wolfgang Wurst, and Ralf Kühn
Biochemistry
- You have accessNascent peptides that block protein synthesis in bacteriaChristopher J. Woolstenhulme, Shankar Parajuli, David W. Healey, Diana P. Valverde, E. Nicholas Petersen, Agata L. Starosta, Nicholas R. Guydosh, W. Evan Johnson, Daniel N. Wilson, and Allen R. Buskirk
- Open AccessHost–rabies virus protein–protein interactions as druggable antiviral targetsUsha F. Lingappa, Xianfu Wu, Amanda Macieik, Shao Feng Yu, Andy Atuegbu, Michael Corpuz, Jean Francis, Christine Nichols, Alfredo Calayag, Hong Shi, James A. Ellison, Emma K. T. Harrell, Vinod Asundi, Jaisri R. Lingappa, M. Dharma Prasad, W. Ian Lipkin, Debendranath Dey, Clarence R. Hurt, Vishwanath R. Lingappa, William J. Hansen, and Charles E. Rupprecht
- You have accessDevelopment of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adaptersBirgit Dreier, Annemarie Honegger, Christian Hess, Gabriela Nagy-Davidescu, Peer R. E. Mittl, Markus G. Grütter, Natalya Belousova, Galina Mikheeva, Victor Krasnykh, and Andreas Plückthun
- You have accessInsights into antiamyloidogenic properties of the green tea extract (−)-epigallocatechin-3-gallate toward metal-associated amyloid-β speciesSuk-Joon Hyung, Alaina S. DeToma, Jeffrey R. Brender, Sanghyun Lee, Subramanian Vivekanandan, Akiko Kochi, Jung-Suk Choi, Ayyalusamy Ramamoorthy, Brandon T. Ruotolo, and Mi Hee Lim
- Open AccessProteomic analysis of skeletal organic matrix from the stony coral Stylophora pistillataJeana L. Drake, Tali Mass, Liti Haramaty, Ehud Zelzion, Debashish Bhattacharya, and Paul G. Falkowski
- You have accessMolecular chaperoning function of Ric-8 is to fold nascent heterotrimeric G protein α subunitsPuiYee Chan, Celestine J. Thomas, Stephen R. Sprang, and Gregory G. Tall
- You have accessUBR box N-recognin-4 (UBR4), an N-recognin of the N-end rule pathway, and its role in yolk sac vascular development and autophagyTakafumi Tasaki, Sung Tae Kim, Adriana Zakrzewska, Bo Eun Lee, Min Jueng Kang, Young Dong Yoo, Hyun Joo Cha-Molstad, Joonsung Hwang, Nak Kyun Soung, Ki Sa Sung, Su-Hyeon Kim, Minh Dang Nguyen, Ming Sun, Eugene C. Yi, Bo Yeon Kim, and Yong Tae Kwon
- You have accessCrystal structure of microsomal prostaglandin E2 synthase provides insight into diversity in the MAPEG superfamilyTove Sjögren, Johan Nord, Margareta Ek, Patrik Johansson, Gang Liu, and Stefan Geschwindner
- You have accessStructural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesisLasse Jenner, Agata L. Starosta, Daniel S. Terry, Aleksandra Mikolajka, Liudmila Filonava, Marat Yusupov, Scott C. Blanchard, Daniel N. Wilson, and Gulnara Yusupova
- You have accessLeucyl-tRNA synthetase editing domain functions as a molecular rheostat to control codon ambiguity in Mycoplasma pathogensLi Li, Andrés Palencia, Tiit Lukk, Zhi Li, Zaida A. Luthey-Schulten, Stephen Cusack, Susan A. Martinis, and Michal T. Boniecki
- You have accessThe CORVET complex promotes tethering and fusion of Rab5/Vps21-positive membranesHenning J. kleine Balderhaar, Jens Lachmann, Erdal Yavavli, Cornelia Bröcker, Anna Lürick, and Christian Ungermann
- Open AccessGlobal structural motions from the strain of a single hydrogen bondJens Danielsson, Wael Awad, Kadhirvel Saraboji, Martin Kurnik, Lisa Lang, Lina Leinartaitė, Stefan L. Marklund, Derek T. Logan, and Mikael Oliveberg
- You have accessGeneration of a stable, aminotyrosyl radical-induced α2β2 complex of Escherichia coli class Ia ribonucleotide reductaseEllen C. Minnihan, Nozomi Ando, Edward J. Brignole, Lisa Olshansky, Johnathan Chittuluru, Francisco J. Asturias, Catherine L. Drennan, Daniel G. Nocera, and JoAnne Stubbe
- You have accessMolecular basis for manganese sequestration by calprotectin and roles in the innate immune response to invading bacterial pathogensSteven M. Damo, Thomas E. Kehl-Fie, Norie Sugitani, Marilyn E. Holt, Subodh Rathi, Wesley J. Murphy, Yaofang Zhang, Christine Betz, Laura Hench, Günter Fritz, Eric P. Skaar, and Walter J. Chazin
Biophysics and Computational Biology
- You have accessPhenotypic model for early T-cell activation displaying sensitivity, specificity, and antagonismPaul François, Guillaume Voisinne, Eric D. Siggia, Grégoire Altan-Bonnet, and Massimo Vergassola
- You have accessElasticity, structure, and relaxation of extended proteins under forceGuillaume Stirnemann, David Giganti, Julio M. Fernandez, and B. J. Berne
- You have accessActin cytoskeleton of chemotactic amoebae operates close to the onset of oscillationsChristian Westendorf, Jose Negrete Jr., Albert J. Bae, Rabea Sandmann, Eberhard Bodenschatz, and Carsten Beta
- Open AccessRevealing the competition between peeled ssDNA, melting bubbles, and S-DNA during DNA overstretching using fluorescence microscopyGraeme A. King, Peter Gross, Ulrich Bockelmann, Mauro Modesti, Gijs J. L. Wuite, and Erwin J. G. Peterman
- Open AccessRevealing the competition between peeled ssDNA, melting bubbles, and S-DNA during DNA overstretching by single-molecule calorimetryXinghua Zhang, Hu Chen, Shimin Le, Ioulia Rouzina, Patrick S. Doyle, and Jie Yan
- You have accessSOD1 exhibits allosteric frustration to facilitate metal binding affinityAtanu Das and Steven S. Plotkin
- You have accesseIF4E3 acts as a tumor suppressor by utilizing an atypical mode of methyl-7-guanosine cap recognitionMichael J. Osborne, Laurent Volpon, Jack A. Kornblatt, Biljana Culjkovic-Kraljacic, Aurélie Baguet, and Katherine L. B. Borden
- You have accessDisparities in voltage-sensor charge and electromotility imply slow chloride-driven state transitions in the solute carrier SLC26a5Lei Song and Joseph Santos-Sacchi
- You have accessStructure of Sr-substituted photosystem II at 2.1 Å resolution and its implications in the mechanism of water oxidationFaisal Hammad Mekky Koua, Yasufumi Umena, Keisuke Kawakami, and Jian-Ren Shen
Cell Biology
- You have accessMeiotic HORMA domain proteins prevent untimely centriole disengagement during Caenorhabditis elegans spermatocyte meiosisMara Schvarzstein, Divya Pattabiraman, Joshua N. Bembenek, and Anne M. Villeneuve
- You have accessMOZ increases p53 acetylation and premature senescence through its complex formation with PMLSusumu Rokudai, Oleg Laptenko, Suzzette M. Arnal, Yoichi Taya, Issay Kitabayashi, and Carol Prives
- Open AccessHistone H2B ubiquitin ligase RNF20 is required for MLL-rearranged leukemiaEric Wang, Shinpei Kawaoka, Ming Yu, Junwei Shi, Ting Ni, Wenjing Yang, Jun Zhu, Robert G. Roeder, and Christopher R. Vakoc
- Open AccessColony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogelLiang Jin, Tao Feng, Hung Ping Shih, Ricardo Zerda, Angela Luo, Jasper Hsu, Alborz Mahdavi, Maike Sander, David A. Tirrell, Arthur D. Riggs, and Hsun Teresa Ku
- Open AccessDesign of a superior cytokine antagonist for topical ophthalmic useJinzhao Hou, Sharon A. Townson, Joseph T. Kovalchin, Allyson Masci, Olga Kiner, Yanqun Shu, Bracken M. King, Emily Schirmer, Kathryn Golden, Christoph Thomas, K. Christopher Garcia, Gregory Zarbis-Papastoitsis, Eric S. Furfine, and Thomas M. Barnes
- Open AccessStrengthened glycolysis under hypoxia supports tumor symbiosis and hexosamine biosynthesis in pancreatic adenocarcinomaFabienne Guillaumond, Julie Leca, Orianne Olivares, Marie-Noëlle Lavaut, Nicolas Vidal, Patrice Berthezène, Nelson Javier Dusetti, Céline Loncle, Ezequiel Calvo, Olivier Turrini, Juan Lucio Iovanna, Richard Tomasini, and Sophie Vasseur
- Open AccessAvalanche-like behavior in ciliary importWilliam B. Ludington, Kimberly A. Wemmer, Karl F. Lechtreck, George B. Witman, and Wallace F. Marshall
- You have accessDNA damage in stem cells activates p21, inhibits p53, and induces symmetric self-renewing divisionsAlessandra Insinga, Angelo Cicalese, Mario Faretta, Barbara Gallo, Luisa Albano, Simona Ronzoni, Laura Furia, Andrea Viale, and Pier Giuseppe Pelicci
- You have accessDirect reprogramming by oncogenic Ras and MycIrene Ischenko, Jizu Zhi, Ute M. Moll, Alice Nemajerova, and Oleksi Petrenko
Developmental Biology
- You have accessResponses of hair follicle–associated structures to loss of planar cell polarity signalingHao Chang and Jeremy Nathans
- You have accessRelated F-box proteins control cell death in Caenorhabditis elegans and human lymphomaMichael Chiorazzi, Lixin Rui, Yandan Yang, Michele Ceribelli, Nima Tishbi, Carine W. Maurer, Stella M. Ranuncolo, Hong Zhao, Weihong Xu, Wing-Chung C. Chan, Elaine S. Jaffe, Randy D. Gascoyne, Elias Campo, Andreas Rosenwald, German Ott, Jan Delabie, Lisa M. Rimsza, Shai Shaham, and Louis M. Staudt
Ecology
- You have accessThe steady-state mosaic of disturbance and succession across an old-growth Central Amazon forest landscape
- From the Cover
Jeffrey Q. Chambers, Robinson I. Negron-Juarez, Daniel Magnabosco Marra, Alan Di Vittorio, Joerg Tews, Dar Roberts, Gabriel H. P. M. Ribeiro, Susan E. Trumbore, and Niro Higuchi
Evolution
- You have accessVariants at serotonin transporter and 2A receptor genes predict cooperative behavior differentially according to presence of punishmentKari B. Schroeder, Richard McElreath, and Daniel Nettle
- You have accessLong prereproductive selection and divergence by depth in a Caribbean candelabrum coralCarlos Prada and Michael E. Hellberg
- You have accessFunctional consequences of sequence variation in the pheromone biosynthetic gene pgFAR for Ostrinia mothsJean-Marc Lassance, Marjorie A. Liénard, Binu Antony, Shuguang Qian, Takeshi Fujii, Jun Tabata, Yukio Ishikawa, and Christer Löfstedt
- You have accessPlant mating system transitions drive the macroevolution of defense strategiesStuart A. Campbell and André Kessler
Genetics
- Open AccessWnt and CDK-1 regulate cortical release of WRM-1/β-catenin to control cell division orientation in early Caenorhabditis elegans embryosSoyoung Kim, Takao Ishidate, Rita Sharma, Martha C. Soto, Darryl Conte Jr., Craig C. Mello, and Masaki Shirayama
- You have accessAnatomical and transcriptional dynamics of maize embryonic leaves during seed germinationWen-Yu Liu, Yao-Ming Chang, Sean Chun-Chang Chen, Chen-Hua Lu, Yeh-Hwa Wu, Mei-Yeh Jade Lu, Di-Rong Chen, Arthur Chun-Chieh Shih, Chiou-Rong Sheue, Hsuan-Cheng Huang, Chun-Ping Yu, Hsin-Hung Lin, Shin-Han Shiu, Maurice Sun-Ben Ku, and Wen-Hsiung Li
- Open AccessRare variant detection using family-based sequencing analysisGang Peng, Yu Fan, Timothy B. Palculict, Peidong Shen, E. Cristy Ruteshouser, Aung-Kyaw Chi, Ronald W. Davis, Vicki Huff, Curt Scharfe, and Wenyi Wang
Medical Sciences
- You have accessUnraveling the signaling pathways promoting fibrosis in Dupuytren's disease reveals TNF as a therapeutic targetLiaquat S. Verjee, Jennifer S. N. Verhoekx, James K. K. Chan, Thomas Krausgruber, Vicky Nicolaidou, David Izadi, Dominique Davidson, Marc Feldmann, Kim S. Midwood, and Jagdeep Nanchahal
- You have accessModeling shows that the NS5A inhibitor daclatasvir has two modes of action and yields a shorter estimate of the hepatitis C virus half-lifeJeremie Guedj, Harel Dahari, Libin Rong, Natasha D. Sansone, Richard E. Nettles, Scott J. Cotler, Thomas J. Layden, Susan L. Uprichard, and Alan S. Perelson
- You have accessEngineering of a functional bone organ through endochondral ossificationCeleste Scotti, Elia Piccinini, Hitoshi Takizawa, Atanas Todorov, Paul Bourgine, Adam Papadimitropoulos, Andrea Barbero, Markus G. Manz, and Ivan Martin
- You have accessCotransplantation with specific populations of spina bifida bone marrow stem/progenitor cells enhances urinary bladder regenerationArun K. Sharma, Matthew I. Bury, Natalie J. Fuller, Andrew J. Marks, David M. Kollhoff, Manoj V. Rao, Partha V. Hota, Derek J. Matoka, Seby L. Edassery, Hatim Thaker, John F. Sarwark, Joseph A. Janicki, Guillermo A. Ameer, and Earl Y. Cheng
- Open AccessIntratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamicsAndrea Sottoriva, Inmaculada Spiteri, Sara G. M. Piccirillo, Anestis Touloumis, V. Peter Collins, John C. Marioni, Christina Curtis, Colin Watts, and Simon Tavaré
- You have accessCombined targeting of MEK and PI3K/mTOR effector pathways is necessary to effectively inhibit NRAS mutant melanoma in vitro and in vivoChristian Posch, Homayoun Moslehi, Luzviminda Feeney, Gary A. Green, Anoosheh Ebaee, Valentin Feichtenschlager, Kim Chong, Lily Peng, Michelle T. Dimon, Thomas Phillips, Adil I. Daud, Timothy H. McCalmont, Philip E. LeBoit, and Susana Ortiz-Urda
Microbiology
- You have accessMechanistic link between β barrel assembly and the initiation of autotransporter secretionOlga Pavlova, Janine H. Peterson, Raffaele Ieva, and Harris D. Bernstein
- You have accessEngineering furfural tolerance in Escherichia coli improves the fermentation of lignocellulosic sugars into renewable chemicalsXuan Wang, Lorraine P. Yomano, James Y. Lee, Sean W. York, Huabao Zheng, Michael T. Mullinnix, K. T. Shanmugam, and Lonnie O. Ingram
Neuroscience
- You have accessThe δ2 glutamate receptor gates long-term depression by coordinating interactions between two AMPA receptor phosphorylation sitesKazuhisa Kohda, Wataru Kakegawa, Shinji Matsuda, Tadashi Yamamoto, Hisashi Hirano, and Michisuke Yuzaki
- You have accessMetabotropic NMDA receptor function is required for NMDA receptor-dependent long-term depressionSadegh Nabavi, Helmut W. Kessels, Stephanie Alfonso, Jonathan Aow, Rocky Fox, and Roberto Malinow
- You have accessMetabotropic NMDA receptor function is required for β-amyloid–induced synaptic depressionHelmut W. Kessels, Sadegh Nabavi, and Roberto Malinow
- You have accessDLK initiates a transcriptional program that couples apoptotic and regenerative responses to axonal injuryTrent A. Watkins, Bei Wang, Sarah Huntwork-Rodriguez, Jing Yang, Zhiyu Jiang, Jeffrey Eastham-Anderson, Zora Modrusan, Joshua S. Kaminker, Marc Tessier-Lavigne, and Joseph W. Lewcock
- You have accessFunctional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell deathDerek S. Welsbie, Zhiyong Yang, Yan Ge, Katherine L. Mitchell, Xinrong Zhou, Scott E. Martin, Cynthia A. Berlinicke, Laszlo Hackler Jr., John Fuller, Jie Fu, Li-hui Cao, Bing Han, Douglas Auld, Tian Xue, Syu-ichi Hirai, Lucie Germain, Caroline Simard-Bisson, Richard Blouin, Judy V. Nguyen, Chung-ha O. Davis, Raymond A. Enke, Sanford L. Boye, Shannath L. Merbs, Nicholas Marsh-Armstrong, William W. Hauswirth, Aaron DiAntonio, Robert W. Nickells, James Inglese, Justin Hanes, King-Wai Yau, Harry A. Quigley, and Donald J. Zack
- You have accessSpatial mismatch between the Na+ flux and spike initiation in axon initial segment
- From the Cover
Gytis Baranauskas, Yaron David, and Ilya A. Fleidervish - You have accessSlitrks control excitatory and inhibitory synapse formation with LAR receptor protein tyrosine phosphatases
- From the Cover
Yeong Shin Yim, Younghee Kwon, Jungyong Nam, Hong In Yoon, Kangduk Lee, Dong Goo Kim, Eunjoon Kim, Chul Hoon Kim, and Jaewon Ko - You have accessAmbient noise induces independent shifts in call frequency and amplitude within the Lombard effect in echolocating bats
- From the Cover
Steffen R. Hage, Tinglei Jiang, Sean W. Berquist, Jiang Feng, and Walter Metzner - You have accessReactive astrocytes secrete lcn2 to promote neuron deathFangfang Bi, Cao Huang, Jianbin Tong, Guang Qiu, Bo Huang, Qinxue Wu, Fang Li, Zuoshang Xu, Robert Bowser, Xu-Gang Xia, and Hongxia Zhou
- You have accessRemyelination reporter reveals prolonged refinement of spontaneously regenerated myelinBerit E. Powers, Drew L. Sellers, Emilie A. Lovelett, Willy Cheung, Sheida P. Aalami, Nikolai Zapertov, Don O. Maris, and Philip J. Horner
- You have accessThe protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate mapGina E. Elsen, Rebecca D. Hodge, Francesco Bedogni, Ray A. M. Daza, Branden R. Nelson, Naoko Shiba, Steven L. Reiner, and Robert F. Hevner
- You have accessLarge α-synuclein oligomers inhibit neuronal SNARE-mediated vesicle dockingBong-Kyu Choi, Mal-Gi Choi, Jae-Yeol Kim, Yoosoo Yang, Ying Lai, Dae-Hyuk Kweon, Nam Ki Lee, and Yeon-Kyun Shin
- Open AccessDorsolateral caudate nucleus differentiates cocaine from natural reward-associated contextual cuesHua-Shan Liu, Svetlana Chefer, Hanbing Lu, Karine Guillem, William Rea, Pradeep Kurup, Yihong Yang, Laura Peoples, and Elliot A. Stein
Pharmacology
- You have accessContribution of α7 nicotinic receptor to airway epithelium dysfunction under nicotine exposureKamel Maouche, Kahina Medjber, Jean-Marie Zahm, Franck Delavoie, Christine Terryn, Christelle Coraux, Stéphanie Pons, Isabelle Cloëz-Tayarani, Uwe Maskos, Philippe Birembaut, and Jean-Marie Tournier
Physiology
- Open AccessExtramitochondrial domain rich in carbonic anhydrase activity improves myocardial energeticsMarie A. Schroeder, Mohammad A. Ali, Alzbeta Hulikova, Claudiu T. Supuran, Kieran Clarke, Richard D. Vaughan-Jones, Damian J. Tyler, and Pawel Swietach
- You have accessConvergence of IRBIT, phosphatidylinositol (4,5) bisphosphate, and WNK/SPAK kinases in regulation of the Na+-HCO3− cotransporters familyJeong Hee Hong, Dongki Yang, Nikolay Shcheynikov, Ehud Ohana, Dong Min Shin, and Shmuel Muallem
Plant Biology
- You have accessFlavodiiron proteins Flv1 and Flv3 enable cyanobacterial growth and photosynthesis under fluctuating lightYagut Allahverdiyeva, Henna Mustila, Maria Ermakova, Luca Bersanini, Pierre Richaud, Ghada Ajlani, Natalia Battchikova, Laurent Cournac, and Eva-Mari Aro
- Open Access3′ fragment of miR173-programmed RISC-cleaved RNA is protected from degradation in a complex with RISC and SGS3Manabu Yoshikawa, Taichiro Iki, Yasuhiro Tsutsui, Kyoko Miyashita, R. Scott Poethig, Yoshiki Habu, and Masayuki Ishikawa
Psychological and Cognitive Sciences
- You have accessEvidence suggesting that desire-state attribution may govern food sharing in Eurasian jays
- From the Cover
Ljerka Ostojić, Rachael C. Shaw, Lucy G. Cheke, and Nicola S. Clayton - You have accessStress increases aversive prediction error signal in the ventral striatumOliver J. Robinson, Cassie Overstreet, Danielle R. Charney, Katherine Vytal, and Christian Grillon
Sustainability Science
- Open AccessRecent land use change in the Western Corn Belt threatens grasslands and wetlandsChristopher K. Wright and Michael C. Wimberly
Systems Biology
- You have accessBranching process deconvolution algorithm reveals a detailed cell-cycle transcription programXin Guo, Allister Bernard, David A. Orlando, Steven B. Haase, and Alexander J. Hartemink
- Open AccessRate of environmental change determines stress response specificityJonathan W. Young, James C. W. Locke, and Michael B. Elowitz
Commentaries