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Table of Contents
May 07, 2013; vol. 110 no. 19
This Week in PNAS
Letters (Online Only)
- You have accessIncreased levels of gene therapy may not be beneficial in retinal diseaseEllen Townes-Anderson
- You have accessReply to Townes-Anderson: RPE65 gene therapy does not alter the natural history of retinal degenerationArtur V. Cideciyan, Samuel G. Jacobson, William A. Beltran, William W. Hauswirth, and Gustavo D. Aguirre
See companion article:
- Human retinal gene therapy for LCA- Jan 22, 2013
Opinion
- You have accessHow a nested framework illuminates the challenges of comparative environmental analysis
- Front Matter
Eleanor K. Bors and Susan Solomon
PNAS Plus Significance Statements
Physical Sciences
Applied Physical Sciences
- Open AccessSingle-molecule analysis of combinatorial epigenomic states in normal and tumor cellsPatrick J. Murphy, Benjamin R. Cipriany, Christopher B. Wallin, Chan Yang Ju, Kylan Szeto, James A. Hagarman, Jaime J. Benitez, Harold G. Craighead, and Paul D. Soloway
Chemistry
- You have accessBringing the ocean into the laboratory to probe the chemical complexity of sea spray aerosolKimberly A. Prather, Timothy H. Bertram, Vicki H. Grassian, Grant B. Deane, M. Dale Stokes, Paul J. DeMott, Lihini I. Aluwihare, Brian P. Palenik, Farooq Azam, John H. Seinfeld, Ryan C. Moffet, Mario J. Molina, Christopher D. Cappa, Franz M. Geiger, Gregory C. Roberts, Lynn M. Russell, Andrew P. Ault, Jonas Baltrusaitis, Douglas B. Collins, Craig E. Corrigan, Luis A. Cuadra-Rodriguez, Carlena J. Ebben, Sara D. Forestieri, Timothy L. Guasco, Scott P. Hersey, Michelle J. Kim, William F. Lambert, Robin L. Modini, Wilton Mui, Byron E. Pedler, Matthew J. Ruppel, Olivia S. Ryder, Nathan G. Schoepp, Ryan C. Sullivan, and Defeng Zhao
- You have accessRational design of thermostable vaccines by engineered peptide-induced virus self-biomineralization under physiological conditionsGuangchuan Wang, Rui-Yuan Cao, Rong Chen, Lijuan Mo, Jian-Feng Han, Xiaoyu Wang, Xurong Xu, Tao Jiang, Yong-Qiang Deng, Ke Lyu, Shun-Ya Zhu, E-De Qin, Ruikang Tang, and Cheng-Feng Qin
- You have accessBroadening the scope of glycosyltransferase-catalyzed sugar nucleotide synthesisRichard W. Gantt, Pauline Peltier-Pain, Shanteri Singh, Maoquan Zhou, and Jon S. Thorson
Earth, Atmospheric, and Planetary Sciences
- You have accessPre-Miocene birth of the Yangtze River
- From the Cover
Hongbo Zheng, Peter D. Clift, Ping Wang, Ryuji Tada, Juntao Jia, Mengying He, and Fred Jourdan - You have accessTerrestrial cooling in Northern Europe during the Eocene–Oligocene transitionMichael T. Hren, Nathan D. Sheldon, Stephen T. Grimes, Margaret E. Collinson, Jerry J. Hooker, Melanie Bugler, and Kyger C. Lohmann
- You have accessAssessment of radiative feedback in climate models using satellite observations of annual flux variationYoko Tsushima and Syukuro Manabe
- You have accessOrigin of seasonal predictability for summer climate over the Northwestern PacificYu Kosaka, Shang-Ping Xie, Ngar-Cheung Lau, and Gabriel A. Vecchi
Engineering
- You have accessCharacterizing deformability and surface friction of cancer cellsSangwon Byun, Sungmin Son, Dario Amodei, Nathan Cermak, Josephine Shaw, Joon Ho Kang, Vivian C. Hecht, Monte M. Winslow, Tyler Jacks, Parag Mallick, and Scott R. Manalis
- You have accessGeometric control of vascular networks to enhance engineered tissue integration and functionJan D. Baranski, Ritika R. Chaturvedi, Kelly R. Stevens, Jeroen Eyckmans, Brian Carvalho, Ricardo D. Solorzano, Michael T. Yang, Jordan S. Miller, Sangeeta N. Bhatia, and Christopher S. Chen
Mathematics
Physics
- Open AccessAll-optical control of a solid-state spin using coherent dark statesChristopher G. Yale, Bob B. Buckley, David J. Christle, Guido Burkard, F. Joseph Heremans, Lee C. Bassett, and David D. Awschalom
- You have accessPhase transition in the economically modeled growth of a cellular nervous systemVincenzo Nicosia, Petra E. Vértes, William R. Schafer, Vito Latora, and Edward T. Bullmore
Social Sciences
Anthropology
- You have accessEarly (300−100 B.C.) temple precinct in the Valley of Oaxaca, MexicoElsa M. Redmond and Charles S. Spencer
Economic Sciences
- You have accessAgricultural intensification escalates future conservation costsJacob Phelps, Luis Roman Carrasco, Edward L. Webb, Lian Pin Koh, and Unai Pascual
- You have accessCost-effectiveness of a community-based intervention for reducing the transmission of Schistosoma haematobium and HIV in AfricaMartial L. Ndeffo Mbah, Eyrun F. Kjetland, Katherine E. Atkins, Eric M. Poolman, Evan W. Orenstein, Lauren Ancel Meyers, Jeffrey P. Townsend, and Alison P. Galvani
Psychological and Cognitive Sciences
- Open AccessCoupling social attention to the self forms a network for personal significanceJie Sui, Pia Rotshtein, and Glyn W. Humphreys
- Open AccessLimits in decision making arise from limits in memory retrievalGyslain Giguère and Bradley C. Love
Biological Sciences
Applied Biological Sciences
- You have accessRational design of thermostable vaccines by engineered peptide-induced virus self-biomineralization under physiological conditionsGuangchuan Wang, Rui-Yuan Cao, Rong Chen, Lijuan Mo, Jian-Feng Han, Xiaoyu Wang, Xurong Xu, Tao Jiang, Yong-Qiang Deng, Ke Lyu, Shun-Ya Zhu, E-De Qin, Ruikang Tang, and Cheng-Feng Qin
- You have accessMechanism for the endocytosis of spherical nucleic acid nanoparticle conjugatesChung Hang J. Choi, Liangliang Hao, Suguna P. Narayan, Evelyn Auyeung, and Chad A. Mirkin
- Open AccessA thin polymer membrane, nano-suit, enhancing survival across the continuum between air and high vacuum
- From the Cover
Yasuharu Takaku, Hiroshi Suzuki, Isao Ohta, Daisuke Ishii, Yoshinori Muranaka, Masatsugu Shimomura, and Takahiko Hariyama - Open AccessSynthesis of customized petroleum-replica fuel molecules by targeted modification of free fatty acid pools in Escherichia coliThomas P. Howard, Sabine Middelhaufe, Karen Moore, Christoph Edner, Dagmara M. Kolak, George N. Taylor, David A. Parker, Rob Lee, Nicholas Smirnoff, Stephen J. Aves, and John Love
Biochemistry
- You have accessStructures of complexes comprised of Fischerella transcription factor HetR with Anabaena DNA targetsYoungchang Kim, Zi Ye, Grazyna Joachimiak, Patrick Videau, Jasmine Young, Kathryn Hurd, Sean M. Callahan, Piotr Gornicki, Jindong Zhao, Robert Haselkorn, and Andrzej Joachimiak
- You have accessBroadening the scope of glycosyltransferase-catalyzed sugar nucleotide synthesisRichard W. Gantt, Pauline Peltier-Pain, Shanteri Singh, Maoquan Zhou, and Jon S. Thorson
- You have accessHistone chaperone FACT action during transcription through chromatin by RNA polymerase IIFu-Kai Hsieh, Olga I. Kulaeva, Smita S. Patel, Pamela N. Dyer, Karolin Luger, Danny Reinberg, and Vasily M. Studitsky
- You have accessIdentification and characterization of a previously undescribed family of sequence-specific DNA-binding domainsMatthew B. Lohse, Aaron D. Hernday, Polly M. Fordyce, Liron Noiman, Trevor R. Sorrells, Victor Hanson-Smith, Clarissa J. Nobile, Joseph L. DeRisi, and Alexander D. Johnson
- You have accessPrecise timing of ATPase activation drives targeting of tail-anchored proteinsMichael E. Rome, Meera Rao, William M. Clemons, and Shu-ou Shan
- You have accessPCNA is efficiently loaded on the DNA recombination intermediate to modulate polymerase δ, η, and ζ activitiesJian Li, Donald L. Holzschu, and Tomohiko Sugiyama
- You have accessHolo-TFIID controls the magnitude of a transcription burst and fine-tuning of transcriptionKatie L. Pennington, Sharon K. Marr, Gung-Wei Chirn, and Michael T. Marr II
Biophysics and Computational Biology
- You have accessStepwise protein folding at near amino acid resolution by hydrogen exchange and mass spectrometryWenbing Hu, Benjamin T. Walters, Zhong-Yuan Kan, Leland Mayne, Laura E. Rosen, Susan Marqusee, and S. Walter Englander
- Open AccessMechanism of tyrosine D oxidation in Photosystem IIKeisuke Saito, A. William Rutherford, and Hiroshi Ishikita
- Open AccessTransient formation of water-conducting states in membrane transportersJing Li, Saher A. Shaikh, Giray Enkavi, Po-Chao Wen, Zhijian Huang, and Emad Tajkhorshid
- You have accessDifferent 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediatesLeonardus M. I. Koharudin, Lin Liu, and Angela M. Gronenborn
Cell Biology
- You have accessE4orf4 induces PP2A- and Src-dependent cell death in Drosophila melanogaster and at the same time inhibits classic apoptosis pathwaysAntonina Pechkovsky, Maoz Lahav, Eliya Bitman, Adi Salzberg, and Tamar Kleinberger
- You have accessCharacterizing deformability and surface friction of cancer cellsSangwon Byun, Sungmin Son, Dario Amodei, Nathan Cermak, Josephine Shaw, Joon Ho Kang, Vivian C. Hecht, Monte M. Winslow, Tyler Jacks, Parag Mallick, and Scott R. Manalis
- Open AccessLong tethers provide high-force coupling of the Dam1 ring to shortening microtubulesVladimir A. Volkov, Anatoly V. Zaytsev, Nikita Gudimchuk, Paula M. Grissom, Alexander L. Gintsburg, Fazly I. Ataullakhanov, J. Richard McIntosh, and Ekaterina L. Grishchuk
- You have accessAncestral amphibian v2rs are expressed in the main olfactory epitheliumAdnan S. Syed, Alfredo Sansone, Walter Nadler, Ivan Manzini, and Sigrun I. Korsching
- You have accessMicrohomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cellsLan N. Truong, Yongjiang Li, Linda Z. Shi, Patty Yi-Hwa Hwang, Jing He, Hailong Wang, Niema Razavian, Michael W. Berns, and Xiaohua Wu
- You have accessCigarette smoke (CS) and nicotine delay neutrophil spontaneous death via suppressing production of diphosphoinositol pentakisphosphateYuanfu Xu, Hongmei Li, Besnik Bajrami, Hyunjeong Kwak, Shannan Cao, Peng Liu, Jiaxi Zhou, Yuan Zhou, Haiyan Zhu, Keqiang Ye, and Hongbo R. Luo
Developmental Biology
- You have accessCastor is required for Hedgehog-dependent cell-fate specification and follicle stem cell maintenance in Drosophila oogenesisYu-Chiuan Chang, Anna C.-C. Jang, Cheng-Han Lin, and Denise J. Montell
- Open AccessHippo-Foxa2 signaling pathway plays a role in peripheral lung maturation and surfactant homeostasisChaeuk Chung, Tackhoon Kim, Miju Kim, Minchul Kim, Hoogeun Song, Tae-Shin Kim, Eunjeong Seo, Sang-Hee Lee, Hanbyul Kim, Sang Kyum Kim, Geon Yoo, Da-Hye Lee, Deog-Su Hwang, Tatsuo Kinashi, Jin-Man Kim, and Dae-Sik Lim
Ecology
- You have accessCentrality in primate–parasite networks reveals the potential for the transmission of emerging infectious diseases to humansJosé María Gómez, Charles L. Nunn, and Miguel Verdú
- You have accessOrganic-matter loading determines regime shifts and alternative states in an aquatic ecosystemJennie Sirota, Benjamin Baiser, Nicholas J. Gotelli, and Aaron M. Ellison
Environmental Sciences
- You have accessPre-Miocene birth of the Yangtze River
- From the Cover
Hongbo Zheng, Peter D. Clift, Ping Wang, Ryuji Tada, Juntao Jia, Mengying He, and Fred Jourdan
Evolution
- Open AccessGenomic rearrangements and the evolution of clusters of locally adaptive lociSam Yeaman
- Open AccessInterdomain lateral gene transfer of an essential ferrochelatase gene in human parasitic nematodesBo Wu, Jacopo Novelli, Daojun Jiang, Harry A. Dailey, Frédéric Landmann, Louise Ford, Mark J. Taylor, Clotilde K. S. Carlow, Sanjay Kumar, Jeremy M. Foster, and Barton E. Slatko
- Open AccessNeutral forces acting on intragenomic variability shape the Escherichia coli regulatory network topologyTroy Ruths and Luay Nakhleh
- You have accessDiversification of the eutherian placenta is associated with changes in the pace of lifeMichael Garratt, Jean-Michel Gaillard, Robert C. Brooks, and Jean-François Lemaître
- You have accessEvolutionary remodeling of global regulatory networks during long-term bacterial adaptation to human hostsSøren Damkiær, Lei Yang, Søren Molin, and Lars Jelsbak
Genetics
- Open AccessDnr1 mutations cause neurodegeneration in Drosophila by activating the innate immune response in the brainYang Cao, Stanislava Chtarbanova, Andrew J. Petersen, and Barry Ganetzky
- Open AccessSingle-molecule analysis of combinatorial epigenomic states in normal and tumor cellsPatrick J. Murphy, Benjamin R. Cipriany, Christopher B. Wallin, Chan Yang Ju, Kylan Szeto, James A. Hagarman, Jaime J. Benitez, Harold G. Craighead, and Paul D. Soloway
- You have accessExpanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration
- From the Cover
Zihui Xu, Mickael Poidevin, Xuekun Li, Yujing Li, Liqi Shu, David L. Nelson, He Li, Chadwick M. Hales, Marla Gearing, Thomas S. Wingo, and Peng JinSee companion article:
- ALS/FTD pathogenesis- Apr 29, 2013
- You have accessAccumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutationMasatoshi Aida, Nesreen Hamad, Andre Stanlie, Nasim A. Begum, and Tasuku Honjo
- You have accessPosition effect on FGF13 associated with X-linked congenital generalized hypertrichosisGina M. DeStefano, Katherine A. Fantauzzo, Lynn Petukhova, Mazen Kurban, Marija Tadin-Strapps, Brynn Levy, Dorothy Warburton, Elizabeth T. Cirulli, Yujun Han, Xiaoyun Sun, Yufeng Shen, Maryam Shirazi, Vaidehi Jobanputra, Rodrigo Cepeda-Valdes, Julio Cesar Salas-Alanis, and Angela M. Christiano
- You have accessLeptin resistance is a secondary consequence of the obesity in ciliopathy mutant miceNicolas F. Berbari, Raymond C. Pasek, Erik B. Malarkey, S. M. Zaki Yazdi, Andrew D. McNair, Wesley R. Lewis, Tim R. Nagy, Robert A. Kesterson, and Bradley K. Yoder
Immunology
- You have accessSoluble IL7Rα potentiates IL-7 bioactivity and promotes autoimmunityWangko Lundström, Steven Highfill, Scott T. R. Walsh, Stephanie Beq, Elizabeth Morse, Ingrid Kockum, Lars Alfredsson, Tomas Olsson, Jan Hillert, and Crystal L. Mackall
- You have accessThe molecular basis for Mucosal-Associated Invariant T cell recognition of MR1 proteinsJacinto López-Sagaseta, Charles L. Dulberger, James E. Crooks, Chelsea D. Parks, Adrienne M. Luoma, Amanda McFedries, Ildiko Van Rhijn, Alan Saghatelian, and Erin J. Adams
- You have accessMetallothioneins negatively regulate IL-27–induced type 1 regulatory T-cell differentiationChuan Wu, Caroline Pot, Lionel Apetoh, Theresa Thalhamer, Bing Zhu, Gopal Murugaiyan, Sheng Xiao, Youjin Lee, Manu Rangachari, Nir Yosef, and Vijay K. Kuchroo
- You have accessVaccinia virus F1L protein promotes virulence by inhibiting inflammasome activationMotti Gerlic, Benjamin Faustin, Antonio Postigo, Eric Chi-Wang Yu, Martina Proell, Naran Gombosuren, Maryla Krajewska, Rachel Flynn, Michael Croft, Michael Way, Arnold Satterthwait, Robert C. Liddington, Shahram Salek-Ardakani, Shu-ichi Matsuzawa, and John C. Reed
- You have accessRhomboid domain-containing protein 3 is a negative regulator of TLR3-triggered natural killer cell activationJuan Liu, Shuxun Liu, Meng Xia, Sheng Xu, Chunmei Wang, Yan Bao, Minghong Jiang, Yue Wu, Tian Xu, and Xuetao Cao
- Open AccessImmune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid productionAlessandro Michelucci, Thekla Cordes, Jenny Ghelfi, Arnaud Pailot, Norbert Reiling, Oliver Goldmann, Tina Binz, André Wegner, Aravind Tallam, Antonio Rausell, Manuel Buttini, Carole L. Linster, Eva Medina, Rudi Balling, and Karsten Hiller
- You have accessTargeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activationNorihito Kawasaki, Jose Luis Vela, Corwin M. Nycholat, Christoph Rademacher, Archana Khurana, Nico van Rooijen, Paul R. Crocker, Mitchell Kronenberg, and James C. Paulson
- You have accessCharacterization of pathogenic human monoclonal autoantibodies against GM-CSFYanni Wang, Christy A. Thomson, Lenka L. Allan, Linda M. Jackson, Melanie Olson, Timothy R. Hercus, Tracy L. Nero, Amanda Turner, Michael W. Parker, Angel L. Lopez, Thomas K. Waddell, Gary P. Anderson, John A. Hamilton, and John W. Schrader
Medical Sciences
- You have accessAurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubulesJiun-Ming Wu, Chiung-Tong Chen, Mohane Selvaraj Coumar, Wen-Hsin Lin, Zi-Jie Chen, John T.-A. Hsu, Yi-Hui Peng, Hui-Yi Shiao, Wen-Hsing Lin, Chang-Ying Chu, Jian-Sung Wu, Chih-Tsung Lin, Ching-Ping Chen, Ching-Cheng Hsueh, Kai-Yen Chang, Li-Pin Kao, Chi-Ying F. Huang, Yu-Sheng Chao, Su-Ying Wu, Hsing-Pang Hsieh, and Ya-Hui Chi
- You have accessMutual antagonism between hypoxia-inducible factors 1α and 2α regulates oxygen sensing and cardio-respiratory homeostasisGuoxiang Yuan, Ying-Jie Peng, Vaddi Damodara Reddy, Vladislav V. Makarenko, Jayasri Nanduri, Shakil A. Khan, Joseph A. Garcia, Ganesh K. Kumar, Gregg L. Semenza, and Nanduri R. Prabhakar
- Open AccessKelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4
- From the Cover
Shigeru Shibata, Junhui Zhang, Jeremy Puthumana, Kathryn L. Stone, and Richard P. LiftonSee companion article:
- Ubiquitination and electrolyte balance- Apr 23, 2013
- You have accessSerum microRNA-122 level correlates with virologic responses to pegylated interferon therapy in chronic hepatitis CTung-Hung Su, Chen-Hua Liu, Chun-Jen Liu, Chi-Ling Chen, Te-Tien Ting, Tai-Chung Tseng, Pei-Jer Chen, Jia-Horng Kao, and Ding-Shinn Chen
- You have accessNuclear receptor corepressor (NCOR1) regulates in vivo actions of a mutated thyroid hormone receptor αLaura Fozzatti, Dong Wook Kim, Jeong Won Park, Mark C. Willingham, Anthony N. Hollenberg, and Sheue-Yann Cheng
Microbiology
- You have accessHPV-18 E6 mutants reveal p53 modulation of viral DNA amplification in organotypic cultures
- Inaugural Article
Eun-Young Kho, Hsu-Kun Wang, N. Sanjib Banerjee, Thomas R. Broker, and Louise T. Chow - Open AccessRate enhancement of bacterial extracellular electron transport involves bound flavin semiquinones
- From the Cover
Akihiro Okamoto, Kazuhito Hashimoto, Kenneth H. Nealson, and Ryuhei NakamuraSee companion article:
- Extracellular electron transfer- Apr 29, 2013
- Open AccessProtection against malaria after immunization by chloroquine prophylaxis and sporozoites is mediated by preerythrocytic immunityElse M. Bijker, Guido J. H. Bastiaens, Anne C. Teirlinck, Geert-Jan van Gemert, Wouter Graumans, Marga van de Vegte-Bolmer, Rianne Siebelink-Stoter, Theo Arens, Karina Teelen, Wiebke Nahrendorf, Edmond J. Remarque, Will Roeffen, Annemieke Jansens, Dunja Zimmerman, Martijn Vos, Ben C. L. van Schaijk, Jorien Wiersma, André J. A. M. van der Ven, Quirijn de Mast, Lisette van Lieshout, Jaco J. Verweij, Cornelus C. Hermsen, Anja Scholzen, and Robert W. Sauerwein
- You have accessConserved glycolipid termini in capsular polysaccharides synthesized by ATP-binding cassette transporter-dependent pathways in Gram-negative pathogensLisa M. Willis, Jacek Stupak, Michele R. Richards, Todd L. Lowary, Jianjun Li, and Chris Whitfield
- Open AccessThe c-ring stoichiometry of ATP synthase is adapted to cell physiological requirements of alkaliphilic Bacillus pseudofirmus OF4Laura Preiss, Adriana L. Klyszejko, David B. Hicks, Jun Liu, Oliver J. Fackelmayer, Özkan Yildiz, Terry A. Krulwich, and Thomas Meier
Neuroscience
- You have accessMapping remodeling of thalamocortical projections in the living reeler mouse brain by diffusion tractographyLaura-Adela Harsan, Csaba Dávid, Marco Reisert, Susanne Schnell, Jürgen Hennig, Dominik von Elverfeldt, and Jochen F. Staiger
- You have accessApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditionsPhilip B. Verghese, Joseph M. Castellano, Kanchan Garai, Yinong Wang, Hong Jiang, Aarti Shah, Guojun Bu, Carl Frieden, and David M. Holtzman
- You have accessTFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicityMickael Decressac, Bengt Mattsson, Pia Weikop, Martin Lundblad, Johan Jakobsson, and Anders Björklund
- You have accessPhase transition in the economically modeled growth of a cellular nervous systemVincenzo Nicosia, Petra E. Vértes, William R. Schafer, Vito Latora, and Edward T. Bullmore
- Open AccessOrigin of intrinsic irregular firing in cortical interneuronsKlaus M. Stiefel, Bernhard Englitz, and Terrence J. Sejnowski
- You have accessAnalogues of simple and complex cells in rhesus monkey auditory cortexBiao Tian, Paweł Kuśmierek, and Josef P. Rauschecker
- You have accessDrosophila ORB protein in two mushroom body output neurons is necessary for long-term memory formationTsung-Pin Pai, Chun-Chao Chen, Hui-Hao Lin, An-Lun Chin, Jason Sih-Yu Lai, Pei-Tseng Lee, Tim Tully, and Ann-Shyn Chiang
- You have accessRapid cell death is preceded by amyloid plaque-mediated oxidative stressHong Xie, Steven Hou, Jun Jiang, Maria Sekutowicz, Jonathan Kelly, and Brian J. Bacskai
- You have accessDifferential targeting of brain stress circuits with a selective glucocorticoid receptor modulatorIoannis Zalachoras, René Houtman, Erika Atucha, Rene Devos, Ans M. I. Tijssen, Pu Hu, Peter M. Lockey, Nicole A. Datson, Joseph K. Belanoff, Paul J. Lucassen, Marian Joëls, E. Ronald de Kloet, Benno Roozendaal, Hazel Hunt, and Onno C. Meijer
- Open AccessModulation of the endoplasmic reticulum–mitochondria interface in Alzheimer’s disease and related modelsLouise Hedskog, Catarina Moreira Pinho, Riccardo Filadi, Annica Rönnbäck, Laura Hertwig, Birgitta Wiehager, Pia Larssen, Sandra Gellhaar, Anna Sandebring, Marie Westerlund, Caroline Graff, Bengt Winblad, Dagmar Galter, Homira Behbahani, Paola Pizzo, Elzbieta Glaser, and Maria Ankarcrona
Pharmacology
- Open AccessDurable tumor regression in genetically altered malignant rhabdoid tumors by inhibition of methyltransferase EZH2Sarah K. Knutson, Natalie M. Warholic, Tim J. Wigle, Christine R. Klaus, Christina J. Allain, Alejandra Raimondi, Margaret Porter Scott, Richard Chesworth, Mikel P. Moyer, Robert A. Copeland, Victoria M. Richon, Roy M. Pollock, Kevin W. Kuntz, and Heike Keilhack
Physiology
- You have accessRenal intercalated cells are rather energized by a proton than a sodium pumpRégine Chambrey, Ingo Kurth, Janos Peti-Peterdi, Pascal Houillier, Jeffrey M. Purkerson, Françoise Leviel, Moritz Hentschke, Anselm A. Zdebik, George J. Schwartz, Christian A. Hübner, and Dominique Eladari
Plant Biology
- Open AccessControl of cell proliferation, endoreduplication, cell size, and cell death by the retinoblastoma-related pathway in maize endospermPaolo A. Sabelli, Yan Liu, Ricardo A. Dante, Lucina E. Lizarraga, Hong N. Nguyen, Sara W. Brown, John P. Klingler, Jingjuan Yu, Evan LaBrant, Tracy M. Layton, Max Feldman, and Brian A. Larkins
- You have accessImprinted expression of genes and small RNA is associated with localized hypomethylation of the maternal genome in rice endospermJessica A. Rodrigues, Randy Ruan, Toshiro Nishimura, Manoj K. Sharma, Rita Sharma, Pamela C. Ronald, Robert L. Fischer, and Daniel Zilberman
- Open AccessA 4-gigabase physical map unlocks the structure and evolution of the complex genome of Aegilops tauschii, the wheat D-genome progenitorMing-Cheng Luo, Yong Q. Gu, Frank M. You, Karin R. Deal, Yaqin Ma, Yuqin Hu, Naxin Huo, Yi Wang, Jirui Wang, Shiyong Chen, Chad M. Jorgensen, Yong Zhang, Patrick E. McGuire, Shiran Pasternak, Joshua C. Stein, Doreen Ware, Melissa Kramer, W. Richard McCombie, Shahryar F. Kianian, Mihaela M. Martis, Klaus F. X. Mayer, Sunish K. Sehgal, Wanlong Li, Bikram S. Gill, Michael W. Bevan, Hana Šimková, Jaroslav Doležel, Song Weining, Gerard R. Lazo, Olin D. Anderson, and Jan Dvorak
- You have accessSalicylic acid interferes with clathrin-mediated endocytic protein traffickingYunlong Du, Ricardo Tejos, Martina Beck, Ellie Himschoot, Hongjiang Li, Silke Robatzek, Steffen Vanneste, and Jiří Friml
Population Biology
- You have accessCost-effectiveness of a community-based intervention for reducing the transmission of Schistosoma haematobium and HIV in AfricaMartial L. Ndeffo Mbah, Eyrun F. Kjetland, Katherine E. Atkins, Eric M. Poolman, Evan W. Orenstein, Lauren Ancel Meyers, Jeffrey P. Townsend, and Alison P. Galvani
Sustainability Science
- You have accessAgricultural intensification escalates future conservation costsJacob Phelps, Luis Roman Carrasco, Edward L. Webb, Lian Pin Koh, and Unai Pascual
Commentaries
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See companion article:
See companion article: