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Table of Contents

May 07, 2013; vol. 110 no. 19

This Week in PNAS

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    In This Issue
    PNAS May 7, 2013 110 (19) 7529-7530; https://doi.org/10.1073/iti1913110

Letters (Online Only)

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    Increased levels of gene therapy may not be beneficial in retinal disease
    Ellen Townes-Anderson
    PNAS May 7, 2013 110 (19) E1705; https://doi.org/10.1073/pnas.1303746110
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    Reply to Townes-Anderson: RPE65 gene therapy does not alter the natural history of retinal degeneration
    Artur V. Cideciyan, Samuel G. Jacobson, William A. Beltran, William W. Hauswirth, and Gustavo D. Aguirre
    PNAS May 7, 2013 110 (19) E1706; https://doi.org/10.1073/pnas.1304296110

    See companion article:

    • Human retinal gene therapy for LCA
      - Jan 22, 2013

Opinion

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    How a nested framework illuminates the challenges of comparative environmental analysis
    • Front Matter
    Eleanor K. Bors and Susan Solomon
    PNAS May 7, 2013 110 (19) 7531-7532; https://doi.org/10.1073/pnas.1306240110

Commentaries

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    Toxic RNA as a driver of disease in a common form of ALS and dementia
    Harry T. Orr
    PNAS May 7, 2013 110 (19) 7533-7534; https://doi.org/10.1073/pnas.1305239110

    See companion article:

    • rGGGGCC repeat and neurodegeneration
      - Apr 03, 2013
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    Control of electrolyte balance through ubiquitination
    Marcela Herrera and Thomas M. Coffman
    PNAS May 7, 2013 110 (19) 7535-7536; https://doi.org/10.1073/pnas.1305242110

    See companion article:

    • CUL3–KLHL3 ubiquitinates and degradates WNK4
      - Apr 01, 2013
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    Controlling electron transfer at the microbe–mineral interface
    David J. Richardson, Julea N. Butt, and Thomas A. Clarke
    PNAS May 7, 2013 110 (19) 7537-7538; https://doi.org/10.1073/pnas.1305244110

    See companion article:

    • Microbial extracellular electron transport
      - Apr 01, 2013

PNAS Plus Significance Statements

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    PNAS Plus Significance Statements
    PNAS May 7, 2013 110 (19) 7539-7541; https://doi.org/10.1073/pnas.ss11019

Physical Sciences

  • Applied Physical Sciences

    • Open Access
      Single-molecule analysis of combinatorial epigenomic states in normal and tumor cells
      Patrick J. Murphy, Benjamin R. Cipriany, Christopher B. Wallin, Chan Yang Ju, Kylan Szeto, James A. Hagarman, Jaime J. Benitez, Harold G. Craighead, and Paul D. Soloway
      PNAS May 7, 2013 110 (19) 7772-7777; https://doi.org/10.1073/pnas.1218495110
  • Chemistry

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      Bringing the ocean into the laboratory to probe the chemical complexity of sea spray aerosol
      Kimberly A. Prather, Timothy H. Bertram, Vicki H. Grassian, Grant B. Deane, M. Dale Stokes, Paul J. DeMott, Lihini I. Aluwihare, Brian P. Palenik, Farooq Azam, John H. Seinfeld, Ryan C. Moffet, Mario J. Molina, Christopher D. Cappa, Franz M. Geiger, Gregory C. Roberts, Lynn M. Russell, Andrew P. Ault, Jonas Baltrusaitis, Douglas B. Collins, Craig E. Corrigan, Luis A. Cuadra-Rodriguez, Carlena J. Ebben, Sara D. Forestieri, Timothy L. Guasco, Scott P. Hersey, Michelle J. Kim, William F. Lambert, Robin L. Modini, Wilton Mui, Byron E. Pedler, Matthew J. Ruppel, Olivia S. Ryder, Nathan G. Schoepp, Ryan C. Sullivan, and Defeng Zhao
      PNAS May 7, 2013 110 (19) 7550-7555; https://doi.org/10.1073/pnas.1300262110
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      Rational design of thermostable vaccines by engineered peptide-induced virus self-biomineralization under physiological conditions
      Guangchuan Wang, Rui-Yuan Cao, Rong Chen, Lijuan Mo, Jian-Feng Han, Xiaoyu Wang, Xurong Xu, Tao Jiang, Yong-Qiang Deng, Ke Lyu, Shun-Ya Zhu, E-De Qin, Ruikang Tang, and Cheng-Feng Qin
      PNAS May 7, 2013 110 (19) 7619-7624; https://doi.org/10.1073/pnas.1300233110
    • You have access
      Broadening the scope of glycosyltransferase-catalyzed sugar nucleotide synthesis
      Richard W. Gantt, Pauline Peltier-Pain, Shanteri Singh, Maoquan Zhou, and Jon S. Thorson
      PNAS May 7, 2013 110 (19) 7648-7653; https://doi.org/10.1073/pnas.1220220110
  • Earth, Atmospheric, and Planetary Sciences

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      Pre-Miocene birth of the Yangtze River
      • From the Cover
      Hongbo Zheng, Peter D. Clift, Ping Wang, Ryuji Tada, Juntao Jia, Mengying He, and Fred Jourdan
      PNAS May 7, 2013 110 (19) 7556-7561; https://doi.org/10.1073/pnas.1216241110
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      Terrestrial cooling in Northern Europe during the Eocene–Oligocene transition
      Michael T. Hren, Nathan D. Sheldon, Stephen T. Grimes, Margaret E. Collinson, Jerry J. Hooker, Melanie Bugler, and Kyger C. Lohmann
      PNAS May 7, 2013 110 (19) 7562-7567; https://doi.org/10.1073/pnas.1210930110
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      Assessment of radiative feedback in climate models using satellite observations of annual flux variation
      Yoko Tsushima and Syukuro Manabe
      PNAS May 7, 2013 110 (19) 7568-7573; https://doi.org/10.1073/pnas.1216174110
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      Origin of seasonal predictability for summer climate over the Northwestern Pacific
      Yu Kosaka, Shang-Ping Xie, Ngar-Cheung Lau, and Gabriel A. Vecchi
      PNAS May 7, 2013 110 (19) 7574-7579; https://doi.org/10.1073/pnas.1215582110
  • Engineering

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      Characterizing deformability and surface friction of cancer cells
      Sangwon Byun, Sungmin Son, Dario Amodei, Nathan Cermak, Josephine Shaw, Joon Ho Kang, Vivian C. Hecht, Monte M. Winslow, Tyler Jacks, Parag Mallick, and Scott R. Manalis
      PNAS May 7, 2013 110 (19) 7580-7585; https://doi.org/10.1073/pnas.1218806110
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      Geometric control of vascular networks to enhance engineered tissue integration and function
      Jan D. Baranski, Ritika R. Chaturvedi, Kelly R. Stevens, Jeroen Eyckmans, Brian Carvalho, Ricardo D. Solorzano, Michael T. Yang, Jordan S. Miller, Sangeeta N. Bhatia, and Christopher S. Chen
      PNAS May 7, 2013 110 (19) 7586-7591; https://doi.org/10.1073/pnas.1217796110
  • Mathematics

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      On Ramanujan’s definition of mock theta function
      Robert C. Rhoades
      PNAS May 7, 2013 110 (19) 7592-7594; https://doi.org/10.1073/pnas.1301046110
  • Physics

    • Open Access
      All-optical control of a solid-state spin using coherent dark states
      Christopher G. Yale, Bob B. Buckley, David J. Christle, Guido Burkard, F. Joseph Heremans, Lee C. Bassett, and David D. Awschalom
      PNAS May 7, 2013 110 (19) 7595-7600; https://doi.org/10.1073/pnas.1305920110
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      Phase transition in the economically modeled growth of a cellular nervous system
      Vincenzo Nicosia, Petra E. Vértes, William R. Schafer, Vito Latora, and Edward T. Bullmore
      PNAS May 7, 2013 110 (19) 7880-7885; https://doi.org/10.1073/pnas.1300753110

Social Sciences

  • Anthropology

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      Early (300−100 B.C.) temple precinct in the Valley of Oaxaca, Mexico
      Elsa M. Redmond and Charles S. Spencer
      PNAS May 7, 2013 110 (19) E1707-E1715; https://doi.org/10.1073/pnas.1305294110
  • Economic Sciences

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      Agricultural intensification escalates future conservation costs
      Jacob Phelps, Luis Roman Carrasco, Edward L. Webb, Lian Pin Koh, and Unai Pascual
      PNAS May 7, 2013 110 (19) 7601-7606; https://doi.org/10.1073/pnas.1220070110
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      Cost-effectiveness of a community-based intervention for reducing the transmission of Schistosoma haematobium and HIV in Africa
      Martial L. Ndeffo Mbah, Eyrun F. Kjetland, Katherine E. Atkins, Eric M. Poolman, Evan W. Orenstein, Lauren Ancel Meyers, Jeffrey P. Townsend, and Alison P. Galvani
      PNAS May 7, 2013 110 (19) 7952-7957; https://doi.org/10.1073/pnas.1221396110
  • Psychological and Cognitive Sciences

    • Open Access
      Coupling social attention to the self forms a network for personal significance
      Jie Sui, Pia Rotshtein, and Glyn W. Humphreys
      PNAS May 7, 2013 110 (19) 7607-7612; https://doi.org/10.1073/pnas.1221862110
    • Open Access
      Limits in decision making arise from limits in memory retrieval
      Gyslain Giguère and Bradley C. Love
      PNAS May 7, 2013 110 (19) 7613-7618; https://doi.org/10.1073/pnas.1219674110

Biological Sciences

  • Applied Biological Sciences

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      Rational design of thermostable vaccines by engineered peptide-induced virus self-biomineralization under physiological conditions
      Guangchuan Wang, Rui-Yuan Cao, Rong Chen, Lijuan Mo, Jian-Feng Han, Xiaoyu Wang, Xurong Xu, Tao Jiang, Yong-Qiang Deng, Ke Lyu, Shun-Ya Zhu, E-De Qin, Ruikang Tang, and Cheng-Feng Qin
      PNAS May 7, 2013 110 (19) 7619-7624; https://doi.org/10.1073/pnas.1300233110
    • You have access
      Mechanism for the endocytosis of spherical nucleic acid nanoparticle conjugates
      Chung Hang J. Choi, Liangliang Hao, Suguna P. Narayan, Evelyn Auyeung, and Chad A. Mirkin
      PNAS May 7, 2013 110 (19) 7625-7630; https://doi.org/10.1073/pnas.1305804110
    • Open Access
      A thin polymer membrane, nano-suit, enhancing survival across the continuum between air and high vacuum
      • From the Cover
      Yasuharu Takaku, Hiroshi Suzuki, Isao Ohta, Daisuke Ishii, Yoshinori Muranaka, Masatsugu Shimomura, and Takahiko Hariyama
      PNAS May 7, 2013 110 (19) 7631-7635; https://doi.org/10.1073/pnas.1221341110
    • Open Access
      Synthesis of customized petroleum-replica fuel molecules by targeted modification of free fatty acid pools in Escherichia coli
      Thomas P. Howard, Sabine Middelhaufe, Karen Moore, Christoph Edner, Dagmara M. Kolak, George N. Taylor, David A. Parker, Rob Lee, Nicholas Smirnoff, Stephen J. Aves, and John Love
      PNAS May 7, 2013 110 (19) 7636-7641; https://doi.org/10.1073/pnas.1215966110
    • You have access
      Transporter-mediated biofuel secretion
      Rupak Doshi, Tuan Nguyen, and Geoffrey Chang
      PNAS May 7, 2013 110 (19) 7642-7647; https://doi.org/10.1073/pnas.1301358110
  • Biochemistry

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      Structures of complexes comprised of Fischerella transcription factor HetR with Anabaena DNA targets
      Youngchang Kim, Zi Ye, Grazyna Joachimiak, Patrick Videau, Jasmine Young, Kathryn Hurd, Sean M. Callahan, Piotr Gornicki, Jindong Zhao, Robert Haselkorn, and Andrzej Joachimiak
      PNAS May 7, 2013 110 (19) E1716-E1723; https://doi.org/10.1073/pnas.1305971110
    • You have access
      Broadening the scope of glycosyltransferase-catalyzed sugar nucleotide synthesis
      Richard W. Gantt, Pauline Peltier-Pain, Shanteri Singh, Maoquan Zhou, and Jon S. Thorson
      PNAS May 7, 2013 110 (19) 7648-7653; https://doi.org/10.1073/pnas.1220220110
    • You have access
      Histone chaperone FACT action during transcription through chromatin by RNA polymerase II
      Fu-Kai Hsieh, Olga I. Kulaeva, Smita S. Patel, Pamela N. Dyer, Karolin Luger, Danny Reinberg, and Vasily M. Studitsky
      PNAS May 7, 2013 110 (19) 7654-7659; https://doi.org/10.1073/pnas.1222198110
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      Identification and characterization of a previously undescribed family of sequence-specific DNA-binding domains
      Matthew B. Lohse, Aaron D. Hernday, Polly M. Fordyce, Liron Noiman, Trevor R. Sorrells, Victor Hanson-Smith, Clarissa J. Nobile, Joseph L. DeRisi, and Alexander D. Johnson
      PNAS May 7, 2013 110 (19) 7660-7665; https://doi.org/10.1073/pnas.1221734110
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      Precise timing of ATPase activation drives targeting of tail-anchored proteins
      Michael E. Rome, Meera Rao, William M. Clemons, and Shu-ou Shan
      PNAS May 7, 2013 110 (19) 7666-7671; https://doi.org/10.1073/pnas.1222054110
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      PCNA is efficiently loaded on the DNA recombination intermediate to modulate polymerase δ, η, and ζ activities
      Jian Li, Donald L. Holzschu, and Tomohiko Sugiyama
      PNAS May 7, 2013 110 (19) 7672-7677; https://doi.org/10.1073/pnas.1222241110
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      Holo-TFIID controls the magnitude of a transcription burst and fine-tuning of transcription
      Katie L. Pennington, Sharon K. Marr, Gung-Wei Chirn, and Michael T. Marr II
      PNAS May 7, 2013 110 (19) 7678-7683; https://doi.org/10.1073/pnas.1221712110
  • Biophysics and Computational Biology

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      Stepwise protein folding at near amino acid resolution by hydrogen exchange and mass spectrometry
      Wenbing Hu, Benjamin T. Walters, Zhong-Yuan Kan, Leland Mayne, Laura E. Rosen, Susan Marqusee, and S. Walter Englander
      PNAS May 7, 2013 110 (19) 7684-7689; https://doi.org/10.1073/pnas.1305887110
    • Open Access
      Mechanism of tyrosine D oxidation in Photosystem II
      Keisuke Saito, A. William Rutherford, and Hiroshi Ishikita
      PNAS May 7, 2013 110 (19) 7690-7695; https://doi.org/10.1073/pnas.1300817110
    • Open Access
      Transient formation of water-conducting states in membrane transporters
      Jing Li, Saher A. Shaikh, Giray Enkavi, Po-Chao Wen, Zhijian Huang, and Emad Tajkhorshid
      PNAS May 7, 2013 110 (19) 7696-7701; https://doi.org/10.1073/pnas.1218986110
    • You have access
      Different 3D domain-swapped oligomeric cyanovirin-N structures suggest trapped folding intermediates
      Leonardus M. I. Koharudin, Lin Liu, and Angela M. Gronenborn
      PNAS May 7, 2013 110 (19) 7702-7707; https://doi.org/10.1073/pnas.1300327110
  • Cell Biology

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      E4orf4 induces PP2A- and Src-dependent cell death in Drosophila melanogaster and at the same time inhibits classic apoptosis pathways
      Antonina Pechkovsky, Maoz Lahav, Eliya Bitman, Adi Salzberg, and Tamar Kleinberger
      PNAS May 7, 2013 110 (19) E1724-E1733; https://doi.org/10.1073/pnas.1220282110
    • You have access
      Characterizing deformability and surface friction of cancer cells
      Sangwon Byun, Sungmin Son, Dario Amodei, Nathan Cermak, Josephine Shaw, Joon Ho Kang, Vivian C. Hecht, Monte M. Winslow, Tyler Jacks, Parag Mallick, and Scott R. Manalis
      PNAS May 7, 2013 110 (19) 7580-7585; https://doi.org/10.1073/pnas.1218806110
    • Open Access
      Long tethers provide high-force coupling of the Dam1 ring to shortening microtubules
      Vladimir A. Volkov, Anatoly V. Zaytsev, Nikita Gudimchuk, Paula M. Grissom, Alexander L. Gintsburg, Fazly I. Ataullakhanov, J. Richard McIntosh, and Ekaterina L. Grishchuk
      PNAS May 7, 2013 110 (19) 7708-7713; https://doi.org/10.1073/pnas.1305821110
    • You have access
      Ancestral amphibian v2rs are expressed in the main olfactory epithelium
      Adnan S. Syed, Alfredo Sansone, Walter Nadler, Ivan Manzini, and Sigrun I. Korsching
      PNAS May 7, 2013 110 (19) 7714-7719; https://doi.org/10.1073/pnas.1302088110
    • You have access
      Microhomology-mediated End Joining and Homologous Recombination share the initial end resection step to repair DNA double-strand breaks in mammalian cells
      Lan N. Truong, Yongjiang Li, Linda Z. Shi, Patty Yi-Hwa Hwang, Jing He, Hailong Wang, Niema Razavian, Michael W. Berns, and Xiaohua Wu
      PNAS May 7, 2013 110 (19) 7720-7725; https://doi.org/10.1073/pnas.1213431110
    • You have access
      Cigarette smoke (CS) and nicotine delay neutrophil spontaneous death via suppressing production of diphosphoinositol pentakisphosphate
      Yuanfu Xu, Hongmei Li, Besnik Bajrami, Hyunjeong Kwak, Shannan Cao, Peng Liu, Jiaxi Zhou, Yuan Zhou, Haiyan Zhu, Keqiang Ye, and Hongbo R. Luo
      PNAS May 7, 2013 110 (19) 7726-7731; https://doi.org/10.1073/pnas.1302906110
  • Developmental Biology

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      Castor is required for Hedgehog-dependent cell-fate specification and follicle stem cell maintenance in Drosophila oogenesis
      Yu-Chiuan Chang, Anna C.-C. Jang, Cheng-Han Lin, and Denise J. Montell
      PNAS May 7, 2013 110 (19) E1734-E1742; https://doi.org/10.1073/pnas.1300725110
    • Open Access
      Hippo-Foxa2 signaling pathway plays a role in peripheral lung maturation and surfactant homeostasis
      Chaeuk Chung, Tackhoon Kim, Miju Kim, Minchul Kim, Hoogeun Song, Tae-Shin Kim, Eunjeong Seo, Sang-Hee Lee, Hanbyul Kim, Sang Kyum Kim, Geon Yoo, Da-Hye Lee, Deog-Su Hwang, Tatsuo Kinashi, Jin-Man Kim, and Dae-Sik Lim
      PNAS May 7, 2013 110 (19) 7732-7737; https://doi.org/10.1073/pnas.1220603110
  • Ecology

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      Centrality in primate–parasite networks reveals the potential for the transmission of emerging infectious diseases to humans
      José María Gómez, Charles L. Nunn, and Miguel Verdú
      PNAS May 7, 2013 110 (19) 7738-7741; https://doi.org/10.1073/pnas.1220716110
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      Organic-matter loading determines regime shifts and alternative states in an aquatic ecosystem
      Jennie Sirota, Benjamin Baiser, Nicholas J. Gotelli, and Aaron M. Ellison
      PNAS May 7, 2013 110 (19) 7742-7747; https://doi.org/10.1073/pnas.1221037110
  • Environmental Sciences

    • You have access
      Pre-Miocene birth of the Yangtze River
      • From the Cover
      Hongbo Zheng, Peter D. Clift, Ping Wang, Ryuji Tada, Juntao Jia, Mengying He, and Fred Jourdan
      PNAS May 7, 2013 110 (19) 7556-7561; https://doi.org/10.1073/pnas.1216241110
  • Evolution

    • Open Access
      Genomic rearrangements and the evolution of clusters of locally adaptive loci
      Sam Yeaman
      PNAS May 7, 2013 110 (19) E1743-E1751; https://doi.org/10.1073/pnas.1219381110
    • Open Access
      Interdomain lateral gene transfer of an essential ferrochelatase gene in human parasitic nematodes
      Bo Wu, Jacopo Novelli, Daojun Jiang, Harry A. Dailey, Frédéric Landmann, Louise Ford, Mark J. Taylor, Clotilde K. S. Carlow, Sanjay Kumar, Jeremy M. Foster, and Barton E. Slatko
      PNAS May 7, 2013 110 (19) 7748-7753; https://doi.org/10.1073/pnas.1304049110
    • Open Access
      Neutral forces acting on intragenomic variability shape the Escherichia coli regulatory network topology
      Troy Ruths and Luay Nakhleh
      PNAS May 7, 2013 110 (19) 7754-7759; https://doi.org/10.1073/pnas.1217630110
    • You have access
      Diversification of the eutherian placenta is associated with changes in the pace of life
      Michael Garratt, Jean-Michel Gaillard, Robert C. Brooks, and Jean-François Lemaître
      PNAS May 7, 2013 110 (19) 7760-7765; https://doi.org/10.1073/pnas.1305018110
    • You have access
      Evolutionary remodeling of global regulatory networks during long-term bacterial adaptation to human hosts
      Søren Damkiær, Lei Yang, Søren Molin, and Lars Jelsbak
      PNAS May 7, 2013 110 (19) 7766-7771; https://doi.org/10.1073/pnas.1221466110
  • Genetics

    • Open Access
      Dnr1 mutations cause neurodegeneration in Drosophila by activating the innate immune response in the brain
      Yang Cao, Stanislava Chtarbanova, Andrew J. Petersen, and Barry Ganetzky
      PNAS May 7, 2013 110 (19) E1752-E1760; https://doi.org/10.1073/pnas.1306220110
    • Open Access
      Single-molecule analysis of combinatorial epigenomic states in normal and tumor cells
      Patrick J. Murphy, Benjamin R. Cipriany, Christopher B. Wallin, Chan Yang Ju, Kylan Szeto, James A. Hagarman, Jaime J. Benitez, Harold G. Craighead, and Paul D. Soloway
      PNAS May 7, 2013 110 (19) 7772-7777; https://doi.org/10.1073/pnas.1218495110
    • You have access
      Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration
      • From the Cover
      Zihui Xu, Mickael Poidevin, Xuekun Li, Yujing Li, Liqi Shu, David L. Nelson, He Li, Chadwick M. Hales, Marla Gearing, Thomas S. Wingo, and Peng Jin
      PNAS May 7, 2013 110 (19) 7778-7783; https://doi.org/10.1073/pnas.1219643110

      See companion article:

      • ALS/FTD pathogenesis
        - Apr 29, 2013
    • You have access
      Accumulation of the FACT complex, as well as histone H3.3, serves as a target marker for somatic hypermutation
      Masatoshi Aida, Nesreen Hamad, Andre Stanlie, Nasim A. Begum, and Tasuku Honjo
      PNAS May 7, 2013 110 (19) 7784-7789; https://doi.org/10.1073/pnas.1305859110
    • You have access
      Position effect on FGF13 associated with X-linked congenital generalized hypertrichosis
      Gina M. DeStefano, Katherine A. Fantauzzo, Lynn Petukhova, Mazen Kurban, Marija Tadin-Strapps, Brynn Levy, Dorothy Warburton, Elizabeth T. Cirulli, Yujun Han, Xiaoyun Sun, Yufeng Shen, Maryam Shirazi, Vaidehi Jobanputra, Rodrigo Cepeda-Valdes, Julio Cesar Salas-Alanis, and Angela M. Christiano
      PNAS May 7, 2013 110 (19) 7790-7795; https://doi.org/10.1073/pnas.1216412110
    • You have access
      Leptin resistance is a secondary consequence of the obesity in ciliopathy mutant mice
      Nicolas F. Berbari, Raymond C. Pasek, Erik B. Malarkey, S. M. Zaki Yazdi, Andrew D. McNair, Wesley R. Lewis, Tim R. Nagy, Robert A. Kesterson, and Bradley K. Yoder
      PNAS May 7, 2013 110 (19) 7796-7801; https://doi.org/10.1073/pnas.1210192110
  • Immunology

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      Soluble IL7Rα potentiates IL-7 bioactivity and promotes autoimmunity
      Wangko Lundström, Steven Highfill, Scott T. R. Walsh, Stephanie Beq, Elizabeth Morse, Ingrid Kockum, Lars Alfredsson, Tomas Olsson, Jan Hillert, and Crystal L. Mackall
      PNAS May 7, 2013 110 (19) E1761-E1770; https://doi.org/10.1073/pnas.1222303110
    • You have access
      The molecular basis for Mucosal-Associated Invariant T cell recognition of MR1 proteins
      Jacinto López-Sagaseta, Charles L. Dulberger, James E. Crooks, Chelsea D. Parks, Adrienne M. Luoma, Amanda McFedries, Ildiko Van Rhijn, Alan Saghatelian, and Erin J. Adams
      PNAS May 7, 2013 110 (19) E1771-E1778; https://doi.org/10.1073/pnas.1222678110
    • You have access
      Metallothioneins negatively regulate IL-27–induced type 1 regulatory T-cell differentiation
      Chuan Wu, Caroline Pot, Lionel Apetoh, Theresa Thalhamer, Bing Zhu, Gopal Murugaiyan, Sheng Xiao, Youjin Lee, Manu Rangachari, Nir Yosef, and Vijay K. Kuchroo
      PNAS May 7, 2013 110 (19) 7802-7807; https://doi.org/10.1073/pnas.1211776110
    • You have access
      Vaccinia virus F1L protein promotes virulence by inhibiting inflammasome activation
      Motti Gerlic, Benjamin Faustin, Antonio Postigo, Eric Chi-Wang Yu, Martina Proell, Naran Gombosuren, Maryla Krajewska, Rachel Flynn, Michael Croft, Michael Way, Arnold Satterthwait, Robert C. Liddington, Shahram Salek-Ardakani, Shu-ichi Matsuzawa, and John C. Reed
      PNAS May 7, 2013 110 (19) 7808-7813; https://doi.org/10.1073/pnas.1215995110
    • You have access
      Rhomboid domain-containing protein 3 is a negative regulator of TLR3-triggered natural killer cell activation
      Juan Liu, Shuxun Liu, Meng Xia, Sheng Xu, Chunmei Wang, Yan Bao, Minghong Jiang, Yue Wu, Tian Xu, and Xuetao Cao
      PNAS May 7, 2013 110 (19) 7814-7819; https://doi.org/10.1073/pnas.1220466110
    • Open Access
      Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production
      Alessandro Michelucci, Thekla Cordes, Jenny Ghelfi, Arnaud Pailot, Norbert Reiling, Oliver Goldmann, Tina Binz, André Wegner, Aravind Tallam, Antonio Rausell, Manuel Buttini, Carole L. Linster, Eva Medina, Rudi Balling, and Karsten Hiller
      PNAS May 7, 2013 110 (19) 7820-7825; https://doi.org/10.1073/pnas.1218599110
    • You have access
      Targeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activation
      Norihito Kawasaki, Jose Luis Vela, Corwin M. Nycholat, Christoph Rademacher, Archana Khurana, Nico van Rooijen, Paul R. Crocker, Mitchell Kronenberg, and James C. Paulson
      PNAS May 7, 2013 110 (19) 7826-7831; https://doi.org/10.1073/pnas.1219888110
    • You have access
      Characterization of pathogenic human monoclonal autoantibodies against GM-CSF
      Yanni Wang, Christy A. Thomson, Lenka L. Allan, Linda M. Jackson, Melanie Olson, Timothy R. Hercus, Tracy L. Nero, Amanda Turner, Michael W. Parker, Angel L. Lopez, Thomas K. Waddell, Gary P. Anderson, John A. Hamilton, and John W. Schrader
      PNAS May 7, 2013 110 (19) 7832-7837; https://doi.org/10.1073/pnas.1216011110
  • Medical Sciences

    • You have access
      Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules
      Jiun-Ming Wu, Chiung-Tong Chen, Mohane Selvaraj Coumar, Wen-Hsin Lin, Zi-Jie Chen, John T.-A. Hsu, Yi-Hui Peng, Hui-Yi Shiao, Wen-Hsing Lin, Chang-Ying Chu, Jian-Sung Wu, Chih-Tsung Lin, Ching-Ping Chen, Ching-Cheng Hsueh, Kai-Yen Chang, Li-Pin Kao, Chi-Ying F. Huang, Yu-Sheng Chao, Su-Ying Wu, Hsing-Pang Hsieh, and Ya-Hui Chi
      PNAS May 7, 2013 110 (19) E1779-E1787; https://doi.org/10.1073/pnas.1220523110
    • You have access
      Mutual antagonism between hypoxia-inducible factors 1α and 2α regulates oxygen sensing and cardio-respiratory homeostasis
      Guoxiang Yuan, Ying-Jie Peng, Vaddi Damodara Reddy, Vladislav V. Makarenko, Jayasri Nanduri, Shakil A. Khan, Joseph A. Garcia, Ganesh K. Kumar, Gregg L. Semenza, and Nanduri R. Prabhakar
      PNAS May 7, 2013 110 (19) E1788-E1796; https://doi.org/10.1073/pnas.1305961110
    • Open Access
      Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4
      • From the Cover
      Shigeru Shibata, Junhui Zhang, Jeremy Puthumana, Kathryn L. Stone, and Richard P. Lifton
      PNAS May 7, 2013 110 (19) 7838-7843; https://doi.org/10.1073/pnas.1304592110

      See companion article:

      • Ubiquitination and electrolyte balance
        - Apr 23, 2013
    • You have access
      Serum microRNA-122 level correlates with virologic responses to pegylated interferon therapy in chronic hepatitis C
      Tung-Hung Su, Chen-Hua Liu, Chun-Jen Liu, Chi-Ling Chen, Te-Tien Ting, Tai-Chung Tseng, Pei-Jer Chen, Jia-Horng Kao, and Ding-Shinn Chen
      PNAS May 7, 2013 110 (19) 7844-7849; https://doi.org/10.1073/pnas.1306138110
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      Nuclear receptor corepressor (NCOR1) regulates in vivo actions of a mutated thyroid hormone receptor α
      Laura Fozzatti, Dong Wook Kim, Jeong Won Park, Mark C. Willingham, Anthony N. Hollenberg, and Sheue-Yann Cheng
      PNAS May 7, 2013 110 (19) 7850-7855; https://doi.org/10.1073/pnas.1222334110
  • Microbiology

    • You have access
      HPV-18 E6 mutants reveal p53 modulation of viral DNA amplification in organotypic cultures
      • Inaugural Article
      Eun-Young Kho, Hsu-Kun Wang, N. Sanjib Banerjee, Thomas R. Broker, and Louise T. Chow
      PNAS May 7, 2013 110 (19) 7542-7549; https://doi.org/10.1073/pnas.1304855110
    • Open Access
      Rate enhancement of bacterial extracellular electron transport involves bound flavin semiquinones
      • From the Cover
      Akihiro Okamoto, Kazuhito Hashimoto, Kenneth H. Nealson, and Ryuhei Nakamura
      PNAS May 7, 2013 110 (19) 7856-7861; https://doi.org/10.1073/pnas.1220823110

      See companion article:

      • Extracellular electron transfer
        - Apr 29, 2013
    • Open Access
      Protection against malaria after immunization by chloroquine prophylaxis and sporozoites is mediated by preerythrocytic immunity
      Else M. Bijker, Guido J. H. Bastiaens, Anne C. Teirlinck, Geert-Jan van Gemert, Wouter Graumans, Marga van de Vegte-Bolmer, Rianne Siebelink-Stoter, Theo Arens, Karina Teelen, Wiebke Nahrendorf, Edmond J. Remarque, Will Roeffen, Annemieke Jansens, Dunja Zimmerman, Martijn Vos, Ben C. L. van Schaijk, Jorien Wiersma, André J. A. M. van der Ven, Quirijn de Mast, Lisette van Lieshout, Jaco J. Verweij, Cornelus C. Hermsen, Anja Scholzen, and Robert W. Sauerwein
      PNAS May 7, 2013 110 (19) 7862-7867; https://doi.org/10.1073/pnas.1220360110
    • You have access
      Conserved glycolipid termini in capsular polysaccharides synthesized by ATP-binding cassette transporter-dependent pathways in Gram-negative pathogens
      Lisa M. Willis, Jacek Stupak, Michele R. Richards, Todd L. Lowary, Jianjun Li, and Chris Whitfield
      PNAS May 7, 2013 110 (19) 7868-7873; https://doi.org/10.1073/pnas.1222317110
    • Open Access
      The c-ring stoichiometry of ATP synthase is adapted to cell physiological requirements of alkaliphilic Bacillus pseudofirmus OF4
      Laura Preiss, Adriana L. Klyszejko, David B. Hicks, Jun Liu, Oliver J. Fackelmayer, Özkan Yildiz, Terry A. Krulwich, and Thomas Meier
      PNAS May 7, 2013 110 (19) 7874-7879; https://doi.org/10.1073/pnas.1303333110
  • Neuroscience

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      Mapping remodeling of thalamocortical projections in the living reeler mouse brain by diffusion tractography
      Laura-Adela Harsan, Csaba Dávid, Marco Reisert, Susanne Schnell, Jürgen Hennig, Dominik von Elverfeldt, and Jochen F. Staiger
      PNAS May 7, 2013 110 (19) E1797-E1806; https://doi.org/10.1073/pnas.1218330110
    • You have access
      ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions
      Philip B. Verghese, Joseph M. Castellano, Kanchan Garai, Yinong Wang, Hong Jiang, Aarti Shah, Guojun Bu, Carl Frieden, and David M. Holtzman
      PNAS May 7, 2013 110 (19) E1807-E1816; https://doi.org/10.1073/pnas.1220484110
    • You have access
      TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity
      Mickael Decressac, Bengt Mattsson, Pia Weikop, Martin Lundblad, Johan Jakobsson, and Anders Björklund
      PNAS May 7, 2013 110 (19) E1817-E1826; https://doi.org/10.1073/pnas.1305623110
    • You have access
      Phase transition in the economically modeled growth of a cellular nervous system
      Vincenzo Nicosia, Petra E. Vértes, William R. Schafer, Vito Latora, and Edward T. Bullmore
      PNAS May 7, 2013 110 (19) 7880-7885; https://doi.org/10.1073/pnas.1300753110
    • Open Access
      Origin of intrinsic irregular firing in cortical interneurons
      Klaus M. Stiefel, Bernhard Englitz, and Terrence J. Sejnowski
      PNAS May 7, 2013 110 (19) 7886-7891; https://doi.org/10.1073/pnas.1305219110
    • You have access
      Analogues of simple and complex cells in rhesus monkey auditory cortex
      Biao Tian, Paweł Kuśmierek, and Josef P. Rauschecker
      PNAS May 7, 2013 110 (19) 7892-7897; https://doi.org/10.1073/pnas.1221062110
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      Drosophila ORB protein in two mushroom body output neurons is necessary for long-term memory formation
      Tsung-Pin Pai, Chun-Chao Chen, Hui-Hao Lin, An-Lun Chin, Jason Sih-Yu Lai, Pei-Tseng Lee, Tim Tully, and Ann-Shyn Chiang
      PNAS May 7, 2013 110 (19) 7898-7903; https://doi.org/10.1073/pnas.1216336110
    • You have access
      Rapid cell death is preceded by amyloid plaque-mediated oxidative stress
      Hong Xie, Steven Hou, Jun Jiang, Maria Sekutowicz, Jonathan Kelly, and Brian J. Bacskai
      PNAS May 7, 2013 110 (19) 7904-7909; https://doi.org/10.1073/pnas.1217938110
    • You have access
      Differential targeting of brain stress circuits with a selective glucocorticoid receptor modulator
      Ioannis Zalachoras, René Houtman, Erika Atucha, Rene Devos, Ans M. I. Tijssen, Pu Hu, Peter M. Lockey, Nicole A. Datson, Joseph K. Belanoff, Paul J. Lucassen, Marian Joëls, E. Ronald de Kloet, Benno Roozendaal, Hazel Hunt, and Onno C. Meijer
      PNAS May 7, 2013 110 (19) 7910-7915; https://doi.org/10.1073/pnas.1219411110
    • Open Access
      Modulation of the endoplasmic reticulum–mitochondria interface in Alzheimer’s disease and related models
      Louise Hedskog, Catarina Moreira Pinho, Riccardo Filadi, Annica Rönnbäck, Laura Hertwig, Birgitta Wiehager, Pia Larssen, Sandra Gellhaar, Anna Sandebring, Marie Westerlund, Caroline Graff, Bengt Winblad, Dagmar Galter, Homira Behbahani, Paola Pizzo, Elzbieta Glaser, and Maria Ankarcrona
      PNAS May 7, 2013 110 (19) 7916-7921; https://doi.org/10.1073/pnas.1300677110
  • Pharmacology

    • Open Access
      Durable tumor regression in genetically altered malignant rhabdoid tumors by inhibition of methyltransferase EZH2
      Sarah K. Knutson, Natalie M. Warholic, Tim J. Wigle, Christine R. Klaus, Christina J. Allain, Alejandra Raimondi, Margaret Porter Scott, Richard Chesworth, Mikel P. Moyer, Robert A. Copeland, Victoria M. Richon, Roy M. Pollock, Kevin W. Kuntz, and Heike Keilhack
      PNAS May 7, 2013 110 (19) 7922-7927; https://doi.org/10.1073/pnas.1303800110
  • Physiology

    • You have access
      Renal intercalated cells are rather energized by a proton than a sodium pump
      Régine Chambrey, Ingo Kurth, Janos Peti-Peterdi, Pascal Houillier, Jeffrey M. Purkerson, Françoise Leviel, Moritz Hentschke, Anselm A. Zdebik, George J. Schwartz, Christian A. Hübner, and Dominique Eladari
      PNAS May 7, 2013 110 (19) 7928-7933; https://doi.org/10.1073/pnas.1221496110
  • Plant Biology

    • Open Access
      Control of cell proliferation, endoreduplication, cell size, and cell death by the retinoblastoma-related pathway in maize endosperm
      Paolo A. Sabelli, Yan Liu, Ricardo A. Dante, Lucina E. Lizarraga, Hong N. Nguyen, Sara W. Brown, John P. Klingler, Jingjuan Yu, Evan LaBrant, Tracy M. Layton, Max Feldman, and Brian A. Larkins
      PNAS May 7, 2013 110 (19) E1827-E1836; https://doi.org/10.1073/pnas.1304903110
    • You have access
      Imprinted expression of genes and small RNA is associated with localized hypomethylation of the maternal genome in rice endosperm
      Jessica A. Rodrigues, Randy Ruan, Toshiro Nishimura, Manoj K. Sharma, Rita Sharma, Pamela C. Ronald, Robert L. Fischer, and Daniel Zilberman
      PNAS May 7, 2013 110 (19) 7934-7939; https://doi.org/10.1073/pnas.1306164110
    • Open Access
      A 4-gigabase physical map unlocks the structure and evolution of the complex genome of Aegilops tauschii, the wheat D-genome progenitor
      Ming-Cheng Luo, Yong Q. Gu, Frank M. You, Karin R. Deal, Yaqin Ma, Yuqin Hu, Naxin Huo, Yi Wang, Jirui Wang, Shiyong Chen, Chad M. Jorgensen, Yong Zhang, Patrick E. McGuire, Shiran Pasternak, Joshua C. Stein, Doreen Ware, Melissa Kramer, W. Richard McCombie, Shahryar F. Kianian, Mihaela M. Martis, Klaus F. X. Mayer, Sunish K. Sehgal, Wanlong Li, Bikram S. Gill, Michael W. Bevan, Hana Šimková, Jaroslav Doležel, Song Weining, Gerard R. Lazo, Olin D. Anderson, and Jan Dvorak
      PNAS May 7, 2013 110 (19) 7940-7945; https://doi.org/10.1073/pnas.1219082110
    • You have access
      Salicylic acid interferes with clathrin-mediated endocytic protein trafficking
      Yunlong Du, Ricardo Tejos, Martina Beck, Ellie Himschoot, Hongjiang Li, Silke Robatzek, Steffen Vanneste, and Jiří Friml
      PNAS May 7, 2013 110 (19) 7946-7951; https://doi.org/10.1073/pnas.1220205110
  • Population Biology

    • You have access
      Cost-effectiveness of a community-based intervention for reducing the transmission of Schistosoma haematobium and HIV in Africa
      Martial L. Ndeffo Mbah, Eyrun F. Kjetland, Katherine E. Atkins, Eric M. Poolman, Evan W. Orenstein, Lauren Ancel Meyers, Jeffrey P. Townsend, and Alison P. Galvani
      PNAS May 7, 2013 110 (19) 7952-7957; https://doi.org/10.1073/pnas.1221396110
  • Sustainability Science

    • You have access
      Agricultural intensification escalates future conservation costs
      Jacob Phelps, Luis Roman Carrasco, Edward L. Webb, Lian Pin Koh, and Unai Pascual
      PNAS May 7, 2013 110 (19) 7601-7606; https://doi.org/10.1073/pnas.1220070110

Corrections

  • You have access
    Correction for Drake et al., Proteomic analysis of skeletal organic matrix from the stony coral Stylophora pistillata
    PNAS May 7, 2013 110 (19) 7958-7959; https://doi.org/10.1073/pnas.1305081110
  • You have access
    Correction for McManus et al., Global analysis of trans-splicing in Drosophila
    PNAS May 7, 2013 110 (19) 7958-7959; https://doi.org/10.1073/pnas.1304972110
  • You have access
    Correction for Barber et al., Association of RIG-I with innate immunity of ducks to influenza
    PNAS May 7, 2013 110 (19) 7958-7959; https://doi.org/10.1073/pnas.1306250110
  • You have access
    Correction for Shankarappa et al., Prolonged nerve blockade delays the onset of neuropathic pain
    PNAS May 7, 2013 110 (19) 7958-7959; https://doi.org/10.1073/pnas.1306394110
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Proceedings of the National Academy of Sciences: 110 (19)
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