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Table of Contents
September 24, 2013; vol. 110 no. 39
This Week in PNAS
Letters (Online Only)
- You have accessAre monarch butterflies true navigators? The jury is still outKaren S. Oberhauser, Orley R. Taylor, Steven M. Reppert, Hugh Dingle, Kelly R. Nail, Robert M. Pyle, and Carl Stenoien
- You have accessReply to Oberhauser et al.: The experimental evidence clearly shows that monarch butterflies are almost certainly not true navigatorsHenrik Mouritsen, Rachael Derbyshire, Julia Stalleicken, Ole Ø. Mouritsen, Barrie J. Frost, and D. Ryan Norris
See companion article:
- Monarch butterflies are not true navigators- Apr 08, 2013
- You have accessReply to Smaers: Getting human frontal lobes in proportionRobert A. Barton and Chris Venditti
See companion article:
- Human frontal lobe size- May 13, 2013
Inner Workings
Profiles
- You have accessProfile of John J. EppigAnn Griswold
See companion article:
- Oocyte control of meiotic arrest- Aug 26, 2013
See companion article:
- MARF1 in mammalian oocytes- Oct 22, 2012
- You have accessProfile of Scott J. HultgrenNicholette Zeliadt
See companion article:
- FimH conformation and virulence- Sep 03, 2013
PNAS Plus Significance Statements
Brief statements written by the authors about the significance of their papers.
Perspective
Physical Sciences
Applied Mathematics
- You have accessProspects of elimination of HIV with test-and-treat strategyMirjam E. Kretzschmar, Maarten F. Schim van der Loeff, Paul J. Birrell, Daniela De Angelis, and Roel A. Coutinho
Applied Physical Sciences
- You have accessDislocation reactions, grain boundaries, and irreversibility in two-dimensional lattices using topological tweezersWilliam T. M. Irvine, Andrew D. Hollingsworth, David G. Grier, and Paul M. Chaikin
- You have accessIn-fiber production of polymeric particles for biosensing and encapsulationJoshua J. Kaufman, Richard Ottman, Guangming Tao, Soroush Shabahang, Esmaeil-Hooman Banaei, Xiangdong Liang, Steven G. Johnson, Yoel Fink, Ratna Chakrabarti, and Ayman F. Abouraddy
- You have accessMicron-scale coherence in interphase chromatin dynamicsAlexandra Zidovska, David A. Weitz, and Timothy J. Mitchison
Chemistry
- You have accessAmmonia binding to the oxygen-evolving complex of photosystem II identifies the solvent-exchangeable oxygen bridge (μ-oxo) of the manganese tetramerMontserrat Pérez Navarro, William M. Ames, Håkan Nilsson, Thomas Lohmiller, Dimitrios A. Pantazis, Leonid Rapatskiy, Marc M. Nowaczyk, Frank Neese, Alain Boussac, Johannes Messinger, Wolfgang Lubitz, and Nicholas Cox
- You have accessDiscovery of the surface polarity gradient on iridescent Morpho butterfly scales reveals a mechanism of their selective vapor response
- From the Cover
Radislav A. Potyrailo, Timothy A. Starkey, Peter Vukusic, Helen Ghiradella, Milana Vasudev, Timothy Bunning, Rajesh R. Naik, Zhexiong Tang, Michael Larsen, Tao Deng, Sheng Zhong, Manuel Palacios, James C. Grande, Gilad Zorn, Gregory Goddard, and Sergey Zalubovsky - You have accessBio-inspired synthesis yields a tricyclic indoline that selectively resensitizes methicillin-resistant Staphylococcus aureus (MRSA) to β-lactam antibiotics
- From the Cover
Jessica D. Podoll, Yongxiang Liu, Le Chang, Shane Walls, Wei Wang, and Xiang Wang - You have accessEfficient water oxidation catalyzed by homogeneous cationic cobalt porphyrins with critical roles for the buffer baseDong Wang and John T. Groves
- You have accessSupramolecular polymers with tunable topologies via hierarchical coordination-driven self-assembly and hydrogen bonding interfacesXuzhou Yan, Shijun Li, James Bryant Pollock, Timothy R. Cook, Jianzhuang Chen, Yanyan Zhang, Xiaofan Ji, Yihua Yu, Feihe Huang, and Peter J. Stang
- You have accessNuclear quantum effects and hydrogen bond fluctuations in waterMichele Ceriotti, Jérôme Cuny, Michele Parrinello, and David E. Manolopoulos
- You have accessWatching energy transfer in metalloporphyrin heterodimers using stimulated X-ray Raman spectroscopyJason D. Biggs, Yu Zhang, Daniel Healion, and Shaul Mukamel
- You have accessProtein domain mimetics as in vivo modulators of hypoxia-inducible factor signalingSwati Kushal, Brooke Bullock Lao, Laura K. Henchey, Ramin Dubey, Hanah Mesallati, Nathaniel J. Traaseth, Bogdan Z. Olenyuk, and Paramjit S. Arora
- Open AccessDevelopment of a histone deacetylase 6 inhibitor and its biological effectsJu-Hee Lee, Adaickapillai Mahendran, Yuanshan Yao, Lang Ngo, Gisela Venta-Perez, Megan L. Choy, Nathaniel Kim, Won-Seok Ham, Ronald Breslow, and Paul A. Marks
Earth, Atmospheric, and Planetary Sciences
- You have accessOxygen isotope anomaly observed in water vapor from Alert, Canada and the implication for the stratosphereYing Lin, Robert N. Clayton, Lin Huang, Noboru Nakamura, and James R. Lyons
See companion article:
- Oxygen isotope anomaly in Arctic water vapor- Nov 15, 2013
- You have accessProcessing of meteoritic organic materials as a possible analog of early molecular evolution in planetary environmentsSandra Pizzarello, Stephen K. Davidowski, Gregory P. Holland, and Lynda B. Williams
Engineering
- Open AccessA chemostat array enables the spatio-temporal analysis of the yeast proteomeNicolas Dénervaud, Johannes Becker, Ricard Delgado-Gonzalo, Pascal Damay, Arun S. Rajkumar, Michael Unser, David Shore, Felix Naef, and Sebastian J. Maerkl
Environmental Sciences
- You have accessRegional and seasonal response of a West Nile virus vector to climate changeCory W. Morin and Andrew C. Comrie
Mathematics
- You have accessWeighted means and Karcher equations of positive operatorsJimmie Lawson and Yongdo Lim
Physics
- You have accessDecisions on the fly in cellular sensory systemsEric D. Siggia and Massimo Vergassola
- You have accessPhase behavior and critical activated dynamics of limited-valence DNA nanostarsSilvia Biffi, Roberto Cerbino, Francesca Bomboi, Elvezia Maria Paraboschi, Rosanna Asselta, Francesco Sciortino, and Tommaso Bellini
- Open AccessCoalescence and genetic diversity in sexual populations under selectionRichard A. Neher, Taylor A. Kessinger, and Boris I. Shraiman
Social Sciences
Economic Sciences
- You have accessThirst-dependent risk preferences in monkeys identify a primitive form of wealthHiroshi Yamada, Agnieszka Tymula, Kenway Louie, and Paul W. Glimcher
Psychological and Cognitive Sciences
- You have accessEarly developmental emergence of human amygdala–prefrontal connectivity after maternal deprivationDylan G. Gee, Laurel J. Gabard-Durnam, Jessica Flannery, Bonnie Goff, Kathryn L. Humphreys, Eva H. Telzer, Todd A. Hare, Susan Y. Bookheimer, and Nim Tottenham
Biological Sciences
Applied Biological Sciences
- Open AccessEfficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis
- From the Cover
Zhonggang Hou, Yan Zhang, Nicholas E. Propson, Sara E. Howden, Li-Fang Chu, Erik J. Sontheimer, and James A. ThomsonSee companion article:
- A variant CRISPR-Cas system for genome editing- Sep 06, 2013
Biochemistry
- You have accessFunctional role of oligomerization for bacterial and plant SWEET sugar transporter familyYuan Hu Xuan, Yi Bing Hu, Li-Qing Chen, Davide Sosso, Daniel C. Ducat, Bi-Huei Hou, and Wolf B. Frommer
- Open AccessUracil in duplex DNA is a substrate for the nucleotide incision repair pathway in human cellsPaulina Prorok, Doria Alili, Christine Saint-Pierre, Didier Gasparutto, Dmitry O. Zharkov, Alexander A. Ishchenko, Barbara Tudek, and Murat K. Saparbaev
- You have accessCYP2R1 is a major, but not exclusive, contributor to 25-hydroxyvitamin D production in vivoJinge G. Zhu, Justin T. Ochalek, Martin Kaufmann, Glenville Jones, and Hector F. DeLuca
- You have accessInvolvement of protein IF2 N domain in ribosomal subunit joining revealed from architecture and function of the full-length initiation factorAngelita Simonetti, Stefano Marzi, Isabelle M. L. Billas, Albert Tsai, Attilio Fabbretti, Alexander G. Myasnikov, Pierre Roblin, Andrea C. Vaiana, Isabelle Hazemann, Daniel Eiler, Thomas A. Steitz, Joseph D. Puglisi, Claudio O. Gualerzi, and Bruno P. Klaholz
See companion article:
- Crystal structure of prokaryotic IF2- Sep 12, 2013
- Open AccessInitiation factor 2 crystal structure reveals a different domain organization from eukaryotic initiation factor 5B and mechanism among translational GTPasesDaniel Eiler, Jinzhong Lin, Angelita Simonetti, Bruno P. Klaholz, and Thomas A. Steitz
See companion article:
- Ribosomal subunit joining by full-length IF2- Sep 12, 2013
- You have accessAcrylamide concentration determines the direction and magnitude of helical membrane protein gel shiftsArianna Rath, Fiona Cunningham, and Charles M. Deber
Biophysics and Computational Biology
- You have accessDecisions on the fly in cellular sensory systemsEric D. Siggia and Massimo Vergassola
- You have accessAmmonia binding to the oxygen-evolving complex of photosystem II identifies the solvent-exchangeable oxygen bridge (μ-oxo) of the manganese tetramerMontserrat Pérez Navarro, William M. Ames, Håkan Nilsson, Thomas Lohmiller, Dimitrios A. Pantazis, Leonid Rapatskiy, Marc M. Nowaczyk, Frank Neese, Alain Boussac, Johannes Messinger, Wolfgang Lubitz, and Nicholas Cox
- Open AccessAssessing the utility of coevolution-based residue–residue contact predictions in a sequence- and structure-rich eraHetunandan Kamisetty, Sergey Ovchinnikov, and David Baker
- You have accessAdaptive hydrophobic and hydrophilic interactions of mussel foot proteins with organic thin filmsJing Yu, Yajing Kan, Michael Rapp, Eric Danner, Wei Wei, Saurabh Das, Dusty R. Miller, Yunfei Chen, J. Herbert Waite, and Jacob N. Israelachvili
- You have accessReconstructing dynamic microRNA-regulated interaction networks
- From the Cover
Marcel H. Schulz, Kusum V. Pandit, Christian L. Lino Cardenas, Namasivayam Ambalavanan, Naftali Kaminski, and Ziv Bar-JosephSee companion article:
- Machine learning and regulatory RNAs- Sep 17, 2013
- You have accessQuantitative analysis of intra-Golgi transport shows intercisternal exchange for all cargoSerge Dmitrieff, Madan Rao, and Pierre Sens
- You have accessSemisynthetic K+ channels show that the constricted conformation of the selectivity filter is not the C-type inactivated statePrasanna K. Devaraneni, Alexander G. Komarov, Corey A. Costantino, Jordan J. Devereaux, Kimberly Matulef, and Francis I. Valiyaveetil
Cell Biology
- Open AccessDevelopment of a histone deacetylase 6 inhibitor and its biological effectsJu-Hee Lee, Adaickapillai Mahendran, Yuanshan Yao, Lang Ngo, Gisela Venta-Perez, Megan L. Choy, Nathaniel Kim, Won-Seok Ham, Ronald Breslow, and Paul A. Marks
- You have accessInhibition of androgen receptor and β-catenin activity in prostate cancerEugine Lee, Aviv Madar, Gregory David, Michael J. Garabedian, Ramanuj DasGupta, and Susan K. Logan
- You have accessDissection of Cdk1–cyclin complexes in vivoPo Hien Ear, Michael J. Booth, Diala Abd-Rabbo, Jacqueline Kowarzyk Moreno, Conrad Hall, Daici Chen, Jackie Vogel, and Stephen W. Michnick
- You have accessLysine 63-linked polyubiquitination is required for EGF receptor degradationFangtian Huang, Xuemei Zeng, Woong Kim, Manimalha Balasubramani, Arola Fortian, Steven P. Gygi, Nathan A. Yates, and Alexander Sorkin
Developmental Biology
- Open AccessRegulation of GDF-11 and myostatin activity by GASP-1 and GASP-2Yun-Sil Lee and Se-Jin Lee
- Open AccessBidirectional communication between oocytes and ovarian follicular somatic cells is required for meiotic arrest of mammalian oocytesKaren Wigglesworth, Kyung-Bon Lee, Marilyn J. O’Brien, Jia Peng, Martin M. Matzuk, and John J. Eppig
See companion article:
- Profile of John J. Eppig- Sep 05, 2013
- You have accessDiscovery of the surface polarity gradient on iridescent Morpho butterfly scales reveals a mechanism of their selective vapor response
- From the Cover
Radislav A. Potyrailo, Timothy A. Starkey, Peter Vukusic, Helen Ghiradella, Milana Vasudev, Timothy Bunning, Rajesh R. Naik, Zhexiong Tang, Michael Larsen, Tao Deng, Sheng Zhong, Manuel Palacios, James C. Grande, Gilad Zorn, Gregory Goddard, and Sergey Zalubovsky
Ecology
- Open AccessHerbivore exploits orally secreted bacteria to suppress plant defensesSeung Ho Chung, Cristina Rosa, Erin D. Scully, Michelle Peiffer, John F. Tooker, Kelli Hoover, Dawn S. Luthe, and Gary W. Felton
Environmental Sciences
- You have accessBroad-scale predictability of carbohydrates and exopolymers in Antarctic and Arctic sea iceGraham J. C. Underwood, Shazia N. Aslam, Christine Michel, Andrea Niemi, Louiza Norman, Klaus M. Meiners, Johanna Laybourn-Parry, Harriet Paterson, and David N. Thomas
Evolution
- You have accessPopulation-genomic insights into the evolutionary origin and fate of obligately asexual Daphnia pulexAbraham E. Tucker, Matthew S. Ackerman, Brian D. Eads, Sen Xu, and Michael Lynch
See companion article:
- Asexuality in Daphnia pulex- Sep 23, 2013
- You have accessTesticular volume is inversely correlated with nurturing-related brain activity in human fathersJennifer S. Mascaro, Patrick D. Hackett, and James K. Rilling
- You have accessChemically armed mercenary ants protect fungus-farming societiesRachelle M. M. Adams, Joanito Liberti, Anders A. Illum, Tappey H. Jones, David R. Nash, and Jacobus J. Boomsma
Genetics
- You have accessComplete mitochondrial genome sequence of a Middle Pleistocene cave bear reconstructed from ultrashort DNA fragmentsJesse Dabney, Michael Knapp, Isabelle Glocke, Marie-Theres Gansauge, Antje Weihmann, Birgit Nickel, Cristina Valdiosera, Nuria García, Svante Pääbo, Juan-Luis Arsuaga, and Matthias Meyer
- You have accessPrimate genome architecture influences structural variation mechanisms and functional consequencesOmer Gokcumen, Verena Tischler, Jelena Tica, Qihui Zhu, Rebecca C. Iskow, Eunjung Lee, Markus Hsi-Yang Fritz, Amy Langdon, Adrian M. Stütz, Pavlos Pavlidis, Vladimir Benes, Ryan E. Mills, Peter J. Park, Charles Lee, and Jan O. Korbel
Immunology
- You have accessDistinct antimicrobial peptide expression determines host species-specific bacterial associationsSören Franzenburg, Jonas Walter, Sven Künzel, Jun Wang, John F. Baines, Thomas C. G. Bosch, and Sebastian Fraune
- Open AccessPolyclonal hyper-IgE mouse model reveals mechanistic insights into antibody class switch recombinationShahram Misaghi, Kate Senger, Tao Sai, Yan Qu, Yonglian Sun, Kajal Hamidzadeh, Allen Nguyen, Zhaoyu Jin, Meijuan Zhou, Donghong Yan, Wei Yu Lin, Zhonghua Lin, Maria N. Lorenzo, Andrew Sebrell, Jiabing Ding, Min Xu, Patrick Caplazi, Cary D. Austin, Mercedesz Balazs, Merone Roose-Girma, Laura DeForge, Søren Warming, Wyne P. Lee, Vishva M. Dixit, and Ali A. Zarrin
- You have accessEts-1 facilitates nuclear entry of NFAT proteins and their recruitment to the IL-2 promoterHsiao-Wei Tsao, Tzong-Shyuan Tai, William Tseng, Hui-Hsin Chang, Roland Grenningloh, Shi-Chuen Miaw, and I-Cheng Ho
Medical Sciences
- You have accessProspects of elimination of HIV with test-and-treat strategyMirjam E. Kretzschmar, Maarten F. Schim van der Loeff, Paul J. Birrell, Daniela De Angelis, and Roel A. Coutinho
- Open AccessBlockade of the purinergic P2Y12 receptor greatly increases the platelet inhibitory actions of nitric oxideNicholas S. Kirkby, Martina H. Lundberg, Melissa V. Chan, Ivana Vojnovic, Antonia B. Solomon, Michael Emerson, Jane A. Mitchell, and Timothy D. Warner
Microbiology
- Open AccessPositively selected FimH residues enhance virulence during urinary tract infection by altering FimH conformation
- Inaugural Article
Drew J. Schwartz, Vasilios Kalas, Jerome S. Pinkner, Swaine L. Chen, Caitlin N. Spaulding, Karen W. Dodson, and Scott J. HultgrenSee companion article:
- Profile of Scott J. Hultgren- Sep 04, 2013
Neuroscience
- You have accessThirst-dependent risk preferences in monkeys identify a primitive form of wealthHiroshi Yamada, Agnieszka Tymula, Kenway Louie, and Paul W. Glimcher
- Open AccessCa2+ channel nanodomains boost local Ca2+ amplitudeMichael R. Tadross, Richard W. Tsien, and David T. Yue
- You have accessPresynaptic gating of excitation in the dorsal raphe nucleus by GABAMariano Soiza-Reilly, Wayne B. Anderson, Christopher W. Vaughan, and Kathryn G. Commons
- You have accessFunctional and structural architecture of the human dorsal frontoparietal attention networkSara M. Szczepanski, Mark A. Pinsk, Malia M. Douglas, Sabine Kastner, and Yuri B. Saalmann
Pharmacology
- You have accessBio-inspired synthesis yields a tricyclic indoline that selectively resensitizes methicillin-resistant Staphylococcus aureus (MRSA) to β-lactam antibiotics
- From the Cover
Jessica D. Podoll, Yongxiang Liu, Le Chang, Shane Walls, Wei Wang, and Xiang Wang - You have accessHydrogen sulphide pathway contributes to the enhanced human platelet aggregation in hyperhomocysteinemiaRoberta d’Emmanuele di Villa Bianca, Emma Mitidieri, Matteo N. D. Di Minno, Nicholas S. Kirkby, Timothy D. Warner, Giovanni Di Minno, Giuseppe Cirino, and Raffaella Sorrentino
Plant Biology
- Open AccessArabidopsis semidwarfs evolved from independent mutations in GA20ox1, ortholog to green revolution dwarf alleles in rice and barleyLuis Barboza, Sigi Effgen, Carlos Alonso-Blanco, Rik Kooke, Joost J. B. Keurentjes, Maarten Koornneef, and Rubén Alcázar
- You have accessSeed shattering in a wild sorghum is conferred by a locus unrelated to domesticationHaibao Tang, Hugo E. Cuevas, Sayan Das, Uzay U. Sezen, Chengbo Zhou, Hui Guo, Valorie H. Goff, Zhengxiang Ge, Thomas E. Clemente, and Andrew H. Paterson
- Open AccessATP-binding cassette transporter controls leaf surface secretion of anticancer drug components in Catharanthus roseusFang Yu and Vincenzo De Luca
Population Biology
- Open AccessCoalescence and genetic diversity in sexual populations under selectionRichard A. Neher, Taylor A. Kessinger, and Boris I. Shraiman
Systems Biology
- Open AccessA chemostat array enables the spatio-temporal analysis of the yeast proteomeNicolas Dénervaud, Johannes Becker, Ricard Delgado-Gonzalo, Pascal Damay, Arun S. Rajkumar, Michael Unser, David Shore, Felix Naef, and Sebastian J. Maerkl
Commentaries
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