Proceedings of the National Academy of Sciences: 110 (39)

New Research In

September 24, 2013; vol. 110 no. 39

This Week in PNAS

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In This Issue
PNAS September 24, 2013 110 (39) 15503-15504; https://doi.org/10.1073/iti3913110

Letters (Online Only)

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Are monarch butterflies true navigators? The jury is still out
Karen S. Oberhauser, Orley R. Taylor, Steven M. Reppert, Hugh Dingle, Kelly R. Nail, Robert M. Pyle, and Carl Stenoien

PNAS September 24, 2013 110 (39) E3680; https://doi.org/10.1073/pnas.1308369110
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Reply to Oberhauser et al.: The experimental evidence clearly shows that monarch butterflies are almost certainly not true navigators
Henrik Mouritsen, Rachael Derbyshire, Julia Stalleicken, Ole Ø. Mouritsen, Barrie J. Frost, and D. Ryan Norris

PNAS September 24, 2013 110 (39) E3681; https://doi.org/10.1073/pnas.1309282110
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Monarch butterflies are not true navigators
- Apr 08, 2013
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How humans stand out in frontal lobe scaling
Jeroen B. Smaers

PNAS September 24, 2013 110 (39) E3682; https://doi.org/10.1073/pnas.1308850110
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Reply to Smaers: Getting human frontal lobes in proportion
Robert A. Barton and Chris Venditti

PNAS September 24, 2013 110 (39) E3683-E3684; https://doi.org/10.1073/pnas.1310334110
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Human frontal lobe size
- May 13, 2013

Inner Workings

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Hunting habits of lions
Front Matter
Sarah C. P. Williams

PNAS September 24, 2013 110 (39) 15505; https://doi.org/10.1073/pnas.1313479110

Profiles

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Profile of John J. Eppig
Ann Griswold

PNAS September 24, 2013 110 (39) 15506-15508; https://doi.org/10.1073/pnas.1315016110
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Oocyte control of meiotic arrest
- Aug 26, 2013

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MARF1 in mammalian oocytes
- Oct 22, 2012
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Profile of Scott J. Hultgren
Nicholette Zeliadt

PNAS September 24, 2013 110 (39) 15509-15511; https://doi.org/10.1073/pnas.1315291110
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FimH conformation and virulence
- Sep 03, 2013

Commentaries

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Reverse engineering the cognitive brain
Gert Cauwenberghs

PNAS September 24, 2013 110 (39) 15512-15513; https://doi.org/10.1073/pnas.1313114110
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Synthesizing cognition in neuromorphic systems
- Jul 22, 2013
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A variant CRISPR-Cas9 system adds versatility to genome engineering
Ryan M. Walsh and Konrad Hochedlinger

PNAS September 24, 2013 110 (39) 15514-15515; https://doi.org/10.1073/pnas.1314697110
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Genome engineering with Cas9 from N. meningitidis
- Aug 12, 2013
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Using machine learning to identify disease-relevant regulatory RNAs
Uwe Ohler

PNAS September 24, 2013 110 (39) 15516-15517; https://doi.org/10.1073/pnas.1315199110
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Dynamic microRNA-regulated interaction networks
- Aug 28, 2013
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Asexual Daphnia genomes expose something old, new, borrowed, and blue
John M. Logsdon Jr.

PNAS September 24, 2013 110 (39) 15518-15519; https://doi.org/10.1073/pnas.1314088110
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Genomic consequences of loss of recombination
- Aug 19, 2013

PNAS Plus Significance Statements

Brief statements written by the authors about the significance of their papers.

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PNAS Plus Significance Statements
PNAS September 24, 2013 110 (39) 15520; https://doi.org/10.1073/pnas.ss11039

Perspective

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DNA cloning: A personal view after 40 years
From the Cover
Stanley N. Cohen

PNAS September 24, 2013 110 (39) 15521-15529; https://doi.org/10.1073/pnas.1313397110

Physical Sciences

Applied Mathematics
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  Prospects of elimination of HIV with test-and-treat strategy
  Mirjam E. Kretzschmar, Maarten F. Schim van der Loeff, Paul J. Birrell, Daniela De Angelis, and Roel A. Coutinho
  
  PNAS September 24, 2013 110 (39) 15538-15543; https://doi.org/10.1073/pnas.1301801110
Applied Physical Sciences
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  Dislocation reactions, grain boundaries, and irreversibility in two-dimensional lattices using topological tweezers
  William T. M. Irvine, Andrew D. Hollingsworth, David G. Grier, and Paul M. Chaikin
  
  PNAS September 24, 2013 110 (39) 15544-15548; https://doi.org/10.1073/pnas.1300787110
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  In-fiber production of polymeric particles for biosensing and encapsulation
  Joshua J. Kaufman, Richard Ottman, Guangming Tao, Soroush Shabahang, Esmaeil-Hooman Banaei, Xiangdong Liang, Steven G. Johnson, Yoel Fink, Ratna Chakrabarti, and Ayman F. Abouraddy
  
  PNAS September 24, 2013 110 (39) 15549-15554; https://doi.org/10.1073/pnas.1310214110
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  Micron-scale coherence in interphase chromatin dynamics
  Alexandra Zidovska, David A. Weitz, and Timothy J. Mitchison
  
  PNAS September 24, 2013 110 (39) 15555-15560; https://doi.org/10.1073/pnas.1220313110
Chemistry
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  Ammonia binding to the oxygen-evolving complex of photosystem II identifies the solvent-exchangeable oxygen bridge (μ-oxo) of the manganese tetramer
  Montserrat Pérez Navarro, William M. Ames, Håkan Nilsson, Thomas Lohmiller, Dimitrios A. Pantazis, Leonid Rapatskiy, Marc M. Nowaczyk, Frank Neese, Alain Boussac, Johannes Messinger, Wolfgang Lubitz, and Nicholas Cox
  
  PNAS September 24, 2013 110 (39) 15561-15566; https://doi.org/10.1073/pnas.1304334110
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  Discovery of the surface polarity gradient on iridescent Morpho butterfly scales reveals a mechanism of their selective vapor response
  From the Cover
  
  Radislav A. Potyrailo, Timothy A. Starkey, Peter Vukusic, Helen Ghiradella, Milana Vasudev, Timothy Bunning, Rajesh R. Naik, Zhexiong Tang, Michael Larsen, Tao Deng, Sheng Zhong, Manuel Palacios, James C. Grande, Gilad Zorn, Gregory Goddard, and Sergey Zalubovsky
  
  PNAS September 24, 2013 110 (39) 15567-15572; https://doi.org/10.1073/pnas.1311196110
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  Bio-inspired synthesis yields a tricyclic indoline that selectively resensitizes methicillin-resistant Staphylococcus aureus (MRSA) to β-lactam antibiotics
  From the Cover
  
  Jessica D. Podoll, Yongxiang Liu, Le Chang, Shane Walls, Wei Wang, and Xiang Wang
  
  PNAS September 24, 2013 110 (39) 15573-15578; https://doi.org/10.1073/pnas.1310459110
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  Efficient water oxidation catalyzed by homogeneous cationic cobalt porphyrins with critical roles for the buffer base
  Dong Wang and John T. Groves
  
  PNAS September 24, 2013 110 (39) 15579-15584; https://doi.org/10.1073/pnas.1315383110
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  Supramolecular polymers with tunable topologies via hierarchical coordination-driven self-assembly and hydrogen bonding interfaces
  Xuzhou Yan, Shijun Li, James Bryant Pollock, Timothy R. Cook, Jianzhuang Chen, Yanyan Zhang, Xiaofan Ji, Yihua Yu, Feihe Huang, and Peter J. Stang
  
  PNAS September 24, 2013 110 (39) 15585-15590; https://doi.org/10.1073/pnas.1307472110
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  Nuclear quantum effects and hydrogen bond fluctuations in water
  Michele Ceriotti, Jérôme Cuny, Michele Parrinello, and David E. Manolopoulos
  
  PNAS September 24, 2013 110 (39) 15591-15596; https://doi.org/10.1073/pnas.1308560110
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  Watching energy transfer in metalloporphyrin heterodimers using stimulated X-ray Raman spectroscopy
  Jason D. Biggs, Yu Zhang, Daniel Healion, and Shaul Mukamel
  
  PNAS September 24, 2013 110 (39) 15597-15601; https://doi.org/10.1073/pnas.1308604110
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  Protein domain mimetics as in vivo modulators of hypoxia-inducible factor signaling
  Swati Kushal, Brooke Bullock Lao, Laura K. Henchey, Ramin Dubey, Hanah Mesallati, Nathaniel J. Traaseth, Bogdan Z. Olenyuk, and Paramjit S. Arora
  
  PNAS September 24, 2013 110 (39) 15602-15607; https://doi.org/10.1073/pnas.1312473110
- Open Access
  Development of a histone deacetylase 6 inhibitor and its biological effects
  Ju-Hee Lee, Adaickapillai Mahendran, Yuanshan Yao, Lang Ngo, Gisela Venta-Perez, Megan L. Choy, Nathaniel Kim, Won-Seok Ham, Ronald Breslow, and Paul A. Marks
  
  PNAS September 24, 2013 110 (39) 15704-15709; https://doi.org/10.1073/pnas.1313893110
Earth, Atmospheric, and Planetary Sciences
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  Oxygen isotope anomaly observed in water vapor from Alert, Canada and the implication for the stratosphere
  Ying Lin, Robert N. Clayton, Lin Huang, Noboru Nakamura, and James R. Lyons
  
  PNAS September 24, 2013 110 (39) 15608-15613; https://doi.org/10.1073/pnas.1313014110
  
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  Oxygen isotope anomaly in Arctic water vapor
  - Nov 15, 2013
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  Processing of meteoritic organic materials as a possible analog of early molecular evolution in planetary environments
  Sandra Pizzarello, Stephen K. Davidowski, Gregory P. Holland, and Lynda B. Williams
  
  PNAS September 24, 2013 110 (39) 15614-15619; https://doi.org/10.1073/pnas.1309113110
Engineering
- Open Access
  A chemostat array enables the spatio-temporal analysis of the yeast proteome
  Nicolas Dénervaud, Johannes Becker, Ricard Delgado-Gonzalo, Pascal Damay, Arun S. Rajkumar, Michael Unser, David Shore, Felix Naef, and Sebastian J. Maerkl
  
  PNAS September 24, 2013 110 (39) 15842-15847; https://doi.org/10.1073/pnas.1308265110
Environmental Sciences
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  Regional and seasonal response of a West Nile virus vector to climate change
  Cory W. Morin and Andrew C. Comrie
  
  PNAS September 24, 2013 110 (39) 15620-15625; https://doi.org/10.1073/pnas.1307135110
Mathematics
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  Weighted means and Karcher equations of positive operators
  Jimmie Lawson and Yongdo Lim
  
  PNAS September 24, 2013 110 (39) 15626-15632; https://doi.org/10.1073/pnas.1313640110
Physics
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  Decisions on the fly in cellular sensory systems
  Eric D. Siggia and Massimo Vergassola
  
  PNAS September 24, 2013 110 (39) E3704-E3712; https://doi.org/10.1073/pnas.1314081110
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  Phase behavior and critical activated dynamics of limited-valence DNA nanostars
  Silvia Biffi, Roberto Cerbino, Francesca Bomboi, Elvezia Maria Paraboschi, Rosanna Asselta, Francesco Sciortino, and Tommaso Bellini
  
  PNAS September 24, 2013 110 (39) 15633-15637; https://doi.org/10.1073/pnas.1304632110
- Open Access
  Coalescence and genetic diversity in sexual populations under selection
  Richard A. Neher, Taylor A. Kessinger, and Boris I. Shraiman
  
  PNAS September 24, 2013 110 (39) 15836-15841; https://doi.org/10.1073/pnas.1309697110

Biological Sciences

Applied Biological Sciences
- Open Access
  Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis
  From the Cover
  
  Zhonggang Hou, Yan Zhang, Nicholas E. Propson, Sara E. Howden, Li-Fang Chu, Erik J. Sontheimer, and James A. Thomson
  
  PNAS September 24, 2013 110 (39) 15644-15649; https://doi.org/10.1073/pnas.1313587110
  
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  A variant CRISPR-Cas system for genome editing
  - Sep 06, 2013
Biochemistry
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  Functional role of oligomerization for bacterial and plant SWEET sugar transporter family
  Yuan Hu Xuan, Yi Bing Hu, Li-Qing Chen, Davide Sosso, Daniel C. Ducat, Bi-Huei Hou, and Wolf B. Frommer
  
  PNAS September 24, 2013 110 (39) E3685-E3694; https://doi.org/10.1073/pnas.1311244110
- Open Access
  Uracil in duplex DNA is a substrate for the nucleotide incision repair pathway in human cells
  Paulina Prorok, Doria Alili, Christine Saint-Pierre, Didier Gasparutto, Dmitry O. Zharkov, Alexander A. Ishchenko, Barbara Tudek, and Murat K. Saparbaev
  
  PNAS September 24, 2013 110 (39) E3695-E3703; https://doi.org/10.1073/pnas.1305624110
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  CYP2R1 is a major, but not exclusive, contributor to 25-hydroxyvitamin D production in vivo
  Jinge G. Zhu, Justin T. Ochalek, Martin Kaufmann, Glenville Jones, and Hector F. DeLuca
  
  PNAS September 24, 2013 110 (39) 15650-15655; https://doi.org/10.1073/pnas.1315006110
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  Involvement of protein IF2 N domain in ribosomal subunit joining revealed from architecture and function of the full-length initiation factor
  Angelita Simonetti, Stefano Marzi, Isabelle M. L. Billas, Albert Tsai, Attilio Fabbretti, Alexander G. Myasnikov, Pierre Roblin, Andrea C. Vaiana, Isabelle Hazemann, Daniel Eiler, Thomas A. Steitz, Joseph D. Puglisi, Claudio O. Gualerzi, and Bruno P. Klaholz
  
  PNAS September 24, 2013 110 (39) 15656-15661; https://doi.org/10.1073/pnas.1309578110
  
  See companion article:
  Crystal structure of prokaryotic IF2
  - Sep 12, 2013
- Open Access
  Initiation factor 2 crystal structure reveals a different domain organization from eukaryotic initiation factor 5B and mechanism among translational GTPases
  Daniel Eiler, Jinzhong Lin, Angelita Simonetti, Bruno P. Klaholz, and Thomas A. Steitz
  
  PNAS September 24, 2013 110 (39) 15662-15667; https://doi.org/10.1073/pnas.1309360110
  
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  Ribosomal subunit joining by full-length IF2
  - Sep 12, 2013
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  Acrylamide concentration determines the direction and magnitude of helical membrane protein gel shifts
  Arianna Rath, Fiona Cunningham, and Charles M. Deber
  
  PNAS September 24, 2013 110 (39) 15668-15673; https://doi.org/10.1073/pnas.1311305110
Biophysics and Computational Biology
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  Decisions on the fly in cellular sensory systems
  Eric D. Siggia and Massimo Vergassola
  
  PNAS September 24, 2013 110 (39) E3704-E3712; https://doi.org/10.1073/pnas.1314081110
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  Ammonia binding to the oxygen-evolving complex of photosystem II identifies the solvent-exchangeable oxygen bridge (μ-oxo) of the manganese tetramer
  Montserrat Pérez Navarro, William M. Ames, Håkan Nilsson, Thomas Lohmiller, Dimitrios A. Pantazis, Leonid Rapatskiy, Marc M. Nowaczyk, Frank Neese, Alain Boussac, Johannes Messinger, Wolfgang Lubitz, and Nicholas Cox
  
  PNAS September 24, 2013 110 (39) 15561-15566; https://doi.org/10.1073/pnas.1304334110
- Open Access
  Assessing the utility of coevolution-based residue–residue contact predictions in a sequence- and structure-rich era
  Hetunandan Kamisetty, Sergey Ovchinnikov, and David Baker
  
  PNAS September 24, 2013 110 (39) 15674-15679; https://doi.org/10.1073/pnas.1314045110
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  Adaptive hydrophobic and hydrophilic interactions of mussel foot proteins with organic thin films
  Jing Yu, Yajing Kan, Michael Rapp, Eric Danner, Wei Wei, Saurabh Das, Dusty R. Miller, Yunfei Chen, J. Herbert Waite, and Jacob N. Israelachvili
  
  PNAS September 24, 2013 110 (39) 15680-15685; https://doi.org/10.1073/pnas.1315015110
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  Reconstructing dynamic microRNA-regulated interaction networks
  From the Cover
  
  Marcel H. Schulz, Kusum V. Pandit, Christian L. Lino Cardenas, Namasivayam Ambalavanan, Naftali Kaminski, and Ziv Bar-Joseph
  
  PNAS September 24, 2013 110 (39) 15686-15691; https://doi.org/10.1073/pnas.1303236110
  
  See companion article:
  Machine learning and regulatory RNAs
  - Sep 17, 2013
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  Quantitative analysis of intra-Golgi transport shows intercisternal exchange for all cargo
  Serge Dmitrieff, Madan Rao, and Pierre Sens
  
  PNAS September 24, 2013 110 (39) 15692-15697; https://doi.org/10.1073/pnas.1303358110
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  Semisynthetic K⁺ channels show that the constricted conformation of the selectivity filter is not the C-type inactivated state
  Prasanna K. Devaraneni, Alexander G. Komarov, Corey A. Costantino, Jordan J. Devereaux, Kimberly Matulef, and Francis I. Valiyaveetil
  
  PNAS September 24, 2013 110 (39) 15698-15703; https://doi.org/10.1073/pnas.1308699110
Cell Biology
- Open Access
  Development of a histone deacetylase 6 inhibitor and its biological effects
  Ju-Hee Lee, Adaickapillai Mahendran, Yuanshan Yao, Lang Ngo, Gisela Venta-Perez, Megan L. Choy, Nathaniel Kim, Won-Seok Ham, Ronald Breslow, and Paul A. Marks
  
  PNAS September 24, 2013 110 (39) 15704-15709; https://doi.org/10.1073/pnas.1313893110
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  Inhibition of androgen receptor and β-catenin activity in prostate cancer
  Eugine Lee, Aviv Madar, Gregory David, Michael J. Garabedian, Ramanuj DasGupta, and Susan K. Logan
  
  PNAS September 24, 2013 110 (39) 15710-15715; https://doi.org/10.1073/pnas.1218168110
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  Dissection of Cdk1–cyclin complexes in vivo
  Po Hien Ear, Michael J. Booth, Diala Abd-Rabbo, Jacqueline Kowarzyk Moreno, Conrad Hall, Daici Chen, Jackie Vogel, and Stephen W. Michnick
  
  PNAS September 24, 2013 110 (39) 15716-15721; https://doi.org/10.1073/pnas.1305420110
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  Lysine 63-linked polyubiquitination is required for EGF receptor degradation
  Fangtian Huang, Xuemei Zeng, Woong Kim, Manimalha Balasubramani, Arola Fortian, Steven P. Gygi, Nathan A. Yates, and Alexander Sorkin
  
  PNAS September 24, 2013 110 (39) 15722-15727; https://doi.org/10.1073/pnas.1308014110
Developmental Biology
- Open Access
  Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2
  Yun-Sil Lee and Se-Jin Lee
  
  PNAS September 24, 2013 110 (39) E3713-E3722; https://doi.org/10.1073/pnas.1309907110
- Open Access
  Bidirectional communication between oocytes and ovarian follicular somatic cells is required for meiotic arrest of mammalian oocytes
  Karen Wigglesworth, Kyung-Bon Lee, Marilyn J. O’Brien, Jia Peng, Martin M. Matzuk, and John J. Eppig
  
  PNAS September 24, 2013 110 (39) E3723-E3729; https://doi.org/10.1073/pnas.1314829110
  
  See companion article:
  Profile of John J. Eppig
  - Sep 05, 2013
- You have access
  Discovery of the surface polarity gradient on iridescent Morpho butterfly scales reveals a mechanism of their selective vapor response
  From the Cover
  
  Radislav A. Potyrailo, Timothy A. Starkey, Peter Vukusic, Helen Ghiradella, Milana Vasudev, Timothy Bunning, Rajesh R. Naik, Zhexiong Tang, Michael Larsen, Tao Deng, Sheng Zhong, Manuel Palacios, James C. Grande, Gilad Zorn, Gregory Goddard, and Sergey Zalubovsky
  
  PNAS September 24, 2013 110 (39) 15567-15572; https://doi.org/10.1073/pnas.1311196110
Ecology
- Open Access
  Herbivore exploits orally secreted bacteria to suppress plant defenses
  Seung Ho Chung, Cristina Rosa, Erin D. Scully, Michelle Peiffer, John F. Tooker, Kelli Hoover, Dawn S. Luthe, and Gary W. Felton
  
  PNAS September 24, 2013 110 (39) 15728-15733; https://doi.org/10.1073/pnas.1308867110
Environmental Sciences
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  Broad-scale predictability of carbohydrates and exopolymers in Antarctic and Arctic sea ice
  Graham J. C. Underwood, Shazia N. Aslam, Christine Michel, Andrea Niemi, Louiza Norman, Klaus M. Meiners, Johanna Laybourn-Parry, Harriet Paterson, and David N. Thomas
  
  PNAS September 24, 2013 110 (39) 15734-15739; https://doi.org/10.1073/pnas.1302870110
Evolution
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  Population-genomic insights into the evolutionary origin and fate of obligately asexual Daphnia pulex
  Abraham E. Tucker, Matthew S. Ackerman, Brian D. Eads, Sen Xu, and Michael Lynch
  
  PNAS September 24, 2013 110 (39) 15740-15745; https://doi.org/10.1073/pnas.1313388110
  
  See companion article:
  Asexuality in Daphnia pulex
  - Sep 23, 2013
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  Testicular volume is inversely correlated with nurturing-related brain activity in human fathers
  Jennifer S. Mascaro, Patrick D. Hackett, and James K. Rilling
  
  PNAS September 24, 2013 110 (39) 15746-15751; https://doi.org/10.1073/pnas.1305579110
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  Chemically armed mercenary ants protect fungus-farming societies
  Rachelle M. M. Adams, Joanito Liberti, Anders A. Illum, Tappey H. Jones, David R. Nash, and Jacobus J. Boomsma
  
  PNAS September 24, 2013 110 (39) 15752-15757; https://doi.org/10.1073/pnas.1311654110
Genetics
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  Complete mitochondrial genome sequence of a Middle Pleistocene cave bear reconstructed from ultrashort DNA fragments
  Jesse Dabney, Michael Knapp, Isabelle Glocke, Marie-Theres Gansauge, Antje Weihmann, Birgit Nickel, Cristina Valdiosera, Nuria García, Svante Pääbo, Juan-Luis Arsuaga, and Matthias Meyer
  
  PNAS September 24, 2013 110 (39) 15758-15763; https://doi.org/10.1073/pnas.1314445110
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  Primate genome architecture influences structural variation mechanisms and functional consequences
  Omer Gokcumen, Verena Tischler, Jelena Tica, Qihui Zhu, Rebecca C. Iskow, Eunjung Lee, Markus Hsi-Yang Fritz, Amy Langdon, Adrian M. Stütz, Pavlos Pavlidis, Vladimir Benes, Ryan E. Mills, Peter J. Park, Charles Lee, and Jan O. Korbel
  
  PNAS September 24, 2013 110 (39) 15764-15769; https://doi.org/10.1073/pnas.1305904110
Immunology
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  Distinct antimicrobial peptide expression determines host species-specific bacterial associations
  Sören Franzenburg, Jonas Walter, Sven Künzel, Jun Wang, John F. Baines, Thomas C. G. Bosch, and Sebastian Fraune
  
  PNAS September 24, 2013 110 (39) E3730-E3738; https://doi.org/10.1073/pnas.1304960110
- Open Access
  Polyclonal hyper-IgE mouse model reveals mechanistic insights into antibody class switch recombination
  Shahram Misaghi, Kate Senger, Tao Sai, Yan Qu, Yonglian Sun, Kajal Hamidzadeh, Allen Nguyen, Zhaoyu Jin, Meijuan Zhou, Donghong Yan, Wei Yu Lin, Zhonghua Lin, Maria N. Lorenzo, Andrew Sebrell, Jiabing Ding, Min Xu, Patrick Caplazi, Cary D. Austin, Mercedesz Balazs, Merone Roose-Girma, Laura DeForge, Søren Warming, Wyne P. Lee, Vishva M. Dixit, and Ali A. Zarrin
  
  PNAS September 24, 2013 110 (39) 15770-15775; https://doi.org/10.1073/pnas.1221661110
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  Ets-1 facilitates nuclear entry of NFAT proteins and their recruitment to the IL-2 promoter
  Hsiao-Wei Tsao, Tzong-Shyuan Tai, William Tseng, Hui-Hsin Chang, Roland Grenningloh, Shi-Chuen Miaw, and I-Cheng Ho
  
  PNAS September 24, 2013 110 (39) 15776-15781; https://doi.org/10.1073/pnas.1304343110
Medical Sciences
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  Prospects of elimination of HIV with test-and-treat strategy
  Mirjam E. Kretzschmar, Maarten F. Schim van der Loeff, Paul J. Birrell, Daniela De Angelis, and Roel A. Coutinho
  
  PNAS September 24, 2013 110 (39) 15538-15543; https://doi.org/10.1073/pnas.1301801110
- Open Access
  Blockade of the purinergic P2Y₁₂ receptor greatly increases the platelet inhibitory actions of nitric oxide
  Nicholas S. Kirkby, Martina H. Lundberg, Melissa V. Chan, Ivana Vojnovic, Antonia B. Solomon, Michael Emerson, Jane A. Mitchell, and Timothy D. Warner
  
  PNAS September 24, 2013 110 (39) 15782-15787; https://doi.org/10.1073/pnas.1218880110
Microbiology
- Open Access
  Positively selected FimH residues enhance virulence during urinary tract infection by altering FimH conformation
  Inaugural Article
  
  Drew J. Schwartz, Vasilios Kalas, Jerome S. Pinkner, Swaine L. Chen, Caitlin N. Spaulding, Karen W. Dodson, and Scott J. Hultgren
  
  PNAS September 24, 2013 110 (39) 15530-15537; https://doi.org/10.1073/pnas.1315203110
  
  See companion article:
  Profile of Scott J. Hultgren
  - Sep 04, 2013
Neuroscience
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  Thirst-dependent risk preferences in monkeys identify a primitive form of wealth
  Hiroshi Yamada, Agnieszka Tymula, Kenway Louie, and Paul W. Glimcher
  
  PNAS September 24, 2013 110 (39) 15788-15793; https://doi.org/10.1073/pnas.1308718110
- Open Access
  Ca²⁺ channel nanodomains boost local Ca²⁺ amplitude
  Michael R. Tadross, Richard W. Tsien, and David T. Yue
  
  PNAS September 24, 2013 110 (39) 15794-15799; https://doi.org/10.1073/pnas.1313898110
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  Presynaptic gating of excitation in the dorsal raphe nucleus by GABA
  Mariano Soiza-Reilly, Wayne B. Anderson, Christopher W. Vaughan, and Kathryn G. Commons
  
  PNAS September 24, 2013 110 (39) 15800-15805; https://doi.org/10.1073/pnas.1304505110
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  Functional and structural architecture of the human dorsal frontoparietal attention network
  Sara M. Szczepanski, Mark A. Pinsk, Malia M. Douglas, Sabine Kastner, and Yuri B. Saalmann
  
  PNAS September 24, 2013 110 (39) 15806-15811; https://doi.org/10.1073/pnas.1313903110
Pharmacology
- You have access
  Bio-inspired synthesis yields a tricyclic indoline that selectively resensitizes methicillin-resistant Staphylococcus aureus (MRSA) to β-lactam antibiotics
  From the Cover
  
  Jessica D. Podoll, Yongxiang Liu, Le Chang, Shane Walls, Wei Wang, and Xiang Wang
  
  PNAS September 24, 2013 110 (39) 15573-15578; https://doi.org/10.1073/pnas.1310459110
- You have access
  Hydrogen sulphide pathway contributes to the enhanced human platelet aggregation in hyperhomocysteinemia
  Roberta d’Emmanuele di Villa Bianca, Emma Mitidieri, Matteo N. D. Di Minno, Nicholas S. Kirkby, Timothy D. Warner, Giovanni Di Minno, Giuseppe Cirino, and Raffaella Sorrentino
  
  PNAS September 24, 2013 110 (39) 15812-15817; https://doi.org/10.1073/pnas.1309049110
Plant Biology
- Open Access
  Arabidopsis semidwarfs evolved from independent mutations in GA20ox1, ortholog to green revolution dwarf alleles in rice and barley
  Luis Barboza, Sigi Effgen, Carlos Alonso-Blanco, Rik Kooke, Joost J. B. Keurentjes, Maarten Koornneef, and Rubén Alcázar
  
  PNAS September 24, 2013 110 (39) 15818-15823; https://doi.org/10.1073/pnas.1314979110
- You have access
  Seed shattering in a wild sorghum is conferred by a locus unrelated to domestication
  Haibao Tang, Hugo E. Cuevas, Sayan Das, Uzay U. Sezen, Chengbo Zhou, Hui Guo, Valorie H. Goff, Zhengxiang Ge, Thomas E. Clemente, and Andrew H. Paterson
  
  PNAS September 24, 2013 110 (39) 15824-15829; https://doi.org/10.1073/pnas.1305213110
- Open Access
  ATP-binding cassette transporter controls leaf surface secretion of anticancer drug components in Catharanthus roseus
  Fang Yu and Vincenzo De Luca
  
  PNAS September 24, 2013 110 (39) 15830-15835; https://doi.org/10.1073/pnas.1307504110
Population Biology
- Open Access
  Coalescence and genetic diversity in sexual populations under selection
  Richard A. Neher, Taylor A. Kessinger, and Boris I. Shraiman
  
  PNAS September 24, 2013 110 (39) 15836-15841; https://doi.org/10.1073/pnas.1309697110
Systems Biology
- Open Access
  A chemostat array enables the spatio-temporal analysis of the yeast proteome
  Nicolas Dénervaud, Johannes Becker, Ricard Delgado-Gonzalo, Pascal Damay, Arun S. Rajkumar, Michael Unser, David Shore, Felix Naef, and Sebastian J. Maerkl
  
  PNAS September 24, 2013 110 (39) 15842-15847; https://doi.org/10.1073/pnas.1308265110

Corrections

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Correction for Gómez Alvarez et al., Unexpectedly high indoor hydroxyl radical concentrations associated with nitrous acid
PNAS September 24, 2013 110 (39) 15848-15849; https://doi.org/10.1073/pnas.1314629110
You have access
Correction for Su et al., 14-3-3σ regulates B-cell homeostasis through stabilization of FOXO1
PNAS September 24, 2013 110 (39) 15849; https://doi.org/10.1073/pnas.1316144110
You have access
Correction for Wang et al., Identification of a small molecule with activity against drug-resistant and persistent tuberculosis
PNAS September 24, 2013 110 (39) 15848-15849; https://doi.org/10.1073/pnas.1315914110

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