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Table of Contents

January 07, 2014; vol. 111 no. 1

This Week in PNAS

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    In This Issue
    PNAS January 7, 2014 111 (1) 1-2; https://doi.org/10.1073/iti0114111

Letters (Online Only)

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    Inconclusive evidence of Juniperus virginiana recovery following sulfur pollution reductions
    Paul G. Schaberg, Gary J. Hawley, Shelly A. Rayback, Joshua M. Halman, and Alexandra M. Kosiba
    PNAS January 7, 2014 111 (1) E1; published ahead of print December 27, 2013. https://doi.org/10.1073/pnas.1320526111
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    Reply to Schaberg et al.: Applying stable isotope analyses to examine the influence of acid deposition on Juniperus virginiana
    Richard B. Thomas, Scott E. Spal, Kenneth R. Smith, and Jesse B. Nippert
    PNAS January 7, 2014 111 (1) E2; published ahead of print December 27, 2013. https://doi.org/10.1073/pnas.1321343111
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    Role for terminal complement activation in amyotrophic lateral sclerosis disease progression
    Trent M. Woodruff, John D. Lee, and Peter G. Noakes
    PNAS January 7, 2014 111 (1) E3-E4; published ahead of print December 31, 2013. https://doi.org/10.1073/pnas.1321248111
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    Reply to Woodruff et al.: C1q and C3-dependent complement pathway activation does not contribute to disease in SOD1 mutant ALS mice
    Christian S. Lobsiger and Don W. Cleveland
    PNAS January 7, 2014 111 (1) E5; published ahead of print December 31, 2013. https://doi.org/10.1073/pnas.1321606111

Profile

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    Profile of Peter Novick
    Sandeep Ravindran
    PNAS January 7, 2014 111 (1) 3-4; published ahead of print December 12, 2013. https://doi.org/10.1073/pnas.1321513110

Commentaries

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    Microbial terroir for wine grapes
    Jack A. Gilbert, Daniel van der Lelie, and Iratxe Zarraonaindia
    PNAS January 7, 2014 111 (1) 5-6; published ahead of print December 5, 2013. https://doi.org/10.1073/pnas.1320471110
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    Mitochondria impact brain function and cognition
    Martin Picard and Bruce S. McEwen
    PNAS January 7, 2014 111 (1) 7-8; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1321881111
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    Role of alternative polyadenylation in epigenetic silencing and antisilencing
    Liuyin Ma, Cheng Guo, and Qingshun Quinn Li
    PNAS January 7, 2014 111 (1) 9-10; published ahead of print December 13, 2013. https://doi.org/10.1073/pnas.1321025111

PNAS Plus Significance Statements

Brief statements written by the authors about the significance of their papers.
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    PNAS Plus Significance Statements
    PNAS January 7, 2014 111 (1) 11-14; https://doi.org/10.1073/pnas.ss11101

Perspective

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    Is the simplest chemical reaction really so simple?
    Justin Jankunas, Mahima Sneha, Richard N. Zare, Foudhil Bouakline, Stuart C. Althorpe, Diego Herráez-Aguilar, and F. Javier Aoiz
    PNAS January 7, 2014 111 (1) 15-20; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1315725111

Physical Sciences

  • Applied Physical Sciences

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      High-resolution photoacoustic tomography of resting-state functional connectivity in the mouse brain
      Mohammadreza Nasiriavanaki, Jun Xia, Hanlin Wan, Adam Quentin Bauer, Joseph P. Culver, and Lihong V. Wang
      PNAS January 7, 2014 111 (1) 21-26; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1311868111
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      Theory of epithelial sheet morphology in three dimensions
      Edouard Hannezo, Jacques Prost, and Jean-Francois Joanny
      PNAS January 7, 2014 111 (1) 27-32; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1312076111
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      Large effect of membrane tension on the fluid–solid phase transitions of two-component phosphatidylcholine vesicles
      Dong Chen and Maria M. Santore
      PNAS January 7, 2014 111 (1) 179-184; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1314993111
  • Chemistry

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      Rationale and mechanism for the low photoinactivation rate of bacteria in plasma
      Jie Chen, Thomas C. Cesario, and Peter M. Rentzepis
      PNAS January 7, 2014 111 (1) 33-38; published ahead of print December 24, 2013. https://doi.org/10.1073/pnas.1315053111
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      Initial stages of calcium uptake and mineral deposition in sea urchin embryos
      Netta Vidavsky, Sefi Addadi, Julia Mahamid, Eyal Shimoni, David Ben-Ezra, Muki Shpigel, Steve Weiner, and Lia Addadi
      PNAS January 7, 2014 111 (1) 39-44; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1312833110
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      Platinum supported on titanium–ruthenium oxide is a remarkably stable electrocatayst for hydrogen fuel cell vehicles
      Javier Parrondo, Taehee Han, Ellazar Niangar, Chunmei Wang, Nilesh Dale, Kev Adjemian, and Vijay Ramani
      PNAS January 7, 2014 111 (1) 45-50; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1319663111
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      Transmembrane allosteric coupling of the gates in a potassium channel
      Benjamin J. Wylie, Manasi P. Bhate, and Ann E. McDermott
      PNAS January 7, 2014 111 (1) 185-190; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1319577110
  • Earth, Atmospheric, and Planetary Sciences

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      Re-Os geochronology and coupled Os-Sr isotope constraints on the Sturtian snowball Earth
      Alan D. Rooney, Francis A. Macdonald, Justin V. Strauss, Francis Ö. Dudás, Christian Hallmann, and David Selby
      PNAS January 7, 2014 111 (1) 51-56; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1317266110
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      Amphitheater-headed canyons formed by megaflooding at Malad Gorge, Idaho
      Michael P. Lamb, Benjamin H. Mackey, and Kenneth A. Farley
      PNAS January 7, 2014 111 (1) 57-62; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1312251111
  • Physics

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      Fe-vacancy order and superconductivity in tetragonal β-Fe1-xSe
      Ta-Kun Chen, Chung-Chieh Chang, Hsian-Hong Chang, Ai-Hua Fang, Chih-Han Wang, Wei-Hsiang Chao, Chuan-Ming Tseng, Yung-Chi Lee, Yu-Ruei Wu, Min-Hsueh Wen, Hsin-Yu Tang, Fu-Rong Chen, Ming-Jye Wang, Maw-Kuen Wu, and Dirk Van Dyck
      PNAS January 7, 2014 111 (1) 63-68; published ahead of print December 18, 2013. https://doi.org/10.1073/pnas.1321160111
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      Kondo conductance across the smallest spin 1/2 radical molecule
      Ryan Requist, Silvio Modesti, Pier Paolo Baruselli, Alexander Smogunov, Michele Fabrizio, and Erio Tosatti
      PNAS January 7, 2014 111 (1) 69-74; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1322239111
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      Avalanches mediate crystallization in a hard-sphere glass
      Eduardo Sanz, Chantal Valeriani, Emanuela Zaccarelli, Wilson C. K. Poon, Michael E. Cates, and Peter N. Pusey
      PNAS January 7, 2014 111 (1) 75-80; published ahead of print December 4, 2013. https://doi.org/10.1073/pnas.1308338110
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      Emerging predictable features of replicated biological invasion fronts
      Andrea Giometto, Andrea Rinaldo, Francesco Carrara, and Florian Altermatt
      PNAS January 7, 2014 111 (1) 297-301; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1321167110
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      Growth feedback as a basis for persister bistability
      Jingchen Feng, David A. Kessler, Eshel Ben-Jacob, and Herbert Levine
      PNAS January 7, 2014 111 (1) 544-549; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1320396110

Social Sciences

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      Evidence supporting an intentional Neandertal burial at La Chapelle-aux-Saints
      William Rendu, Cédric Beauval, Isabelle Crevecoeur, Priscilla Bayle, Antoine Balzeau, Thierry Bismuth, Laurence Bourguignon, Géraldine Delfour, Jean-Philippe Faivre, François Lacrampe-Cuyaubère, Carlotta Tavormina, Dominique Todisco, Alain Turq, and Bruno Maureille
      PNAS January 7, 2014 111 (1) 81-86; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1316780110
  • Psychological and Cognitive Sciences

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      Critical slowing down as early warning for the onset and termination of depression
      • From the Cover
      Ingrid A. van de Leemput, Marieke Wichers, Angélique O. J. Cramer, Denny Borsboom, Francis Tuerlinckx, Peter Kuppens, Egbert H. van Nes, Wolfgang Viechtbauer, Erik J. Giltay, Steven H. Aggen, Catherine Derom, Nele Jacobs, Kenneth S. Kendler, Han L. J. van der Maas, Michael C. Neale, Frenk Peeters, Evert Thiery, Peter Zachar, and Marten Scheffer
      PNAS January 7, 2014 111 (1) 87-92; published ahead of print December 9, 2013. https://doi.org/10.1073/pnas.1312114110
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      Media’s role in broadcasting acute stress following the Boston Marathon bombings
      E. Alison Holman, Dana Rose Garfin, and Roxane Cohen Silver
      PNAS January 7, 2014 111 (1) 93-98; published ahead of print December 9, 2013. https://doi.org/10.1073/pnas.1316265110
  • Social Sciences

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      Dynamic pricing of network goods with boundedly rational consumers
      Roy Radner, Ami Radunskaya, and Arun Sundararajan
      PNAS January 7, 2014 111 (1) 99-104; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1319543110

Biological Sciences

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      Phenalenone-type phytoalexins mediate resistance of banana plants (Musa spp.) to the burrowing nematode Radopholus similis
      Dirk Hölscher, Suganthagunthalam Dhakshinamoorthy, Theodore Alexandrov, Michael Becker, Tom Bretschneider, Andreas Buerkert, Anna C. Crecelius, Dirk De Waele, Annemie Elsen, David G. Heckel, Heike Heklau, Christian Hertweck, Marco Kai, Katrin Knop, Christoph Krafft, Ravi K. Maddula, Christian Matthäus, Jürgen Popp, Bernd Schneider, Ulrich S. Schubert, Richard A. Sikora, Aleš Svatoš, and Rony L. Swennen
      PNAS January 7, 2014 111 (1) 105-110; published ahead of print December 9, 2013. https://doi.org/10.1073/pnas.1314168110
  • Anthropology

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      Cultural assemblages show nested structure in humans and chimpanzees but not orangutans
      Jason M. Kamilar and Quentin D. Atkinson
      PNAS January 7, 2014 111 (1) 111-115; published ahead of print December 9, 2013. https://doi.org/10.1073/pnas.1313318110
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      Earliest evidence for commensal processes of cat domestication
      Yaowu Hu, Songmei Hu, Weilin Wang, Xiaohong Wu, Fiona B. Marshall, Xianglong Chen, Liangliang Hou, and Changsui Wang
      PNAS January 7, 2014 111 (1) 116-120; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1311439110
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      Early Pleistocene third metacarpal from Kenya and the evolution of modern human-like hand morphology
      Carol V. Ward, Matthew W. Tocheri, J. Michael Plavcan, Francis H. Brown, and Fredrick Kyalo Manthi
      PNAS January 7, 2014 111 (1) 121-124; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1316014110
  • Applied Biological Sciences

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      Production and stabilization of the trimeric influenza hemagglutinin stem domain for potentially broadly protective influenza vaccines
      Yuan Lu, John P. Welsh, and James R. Swartz
      PNAS January 7, 2014 111 (1) 125-130; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1308701110
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      Rewiring yeast sugar transporter preference through modifying a conserved protein motif
      Eric M. Young, Alice Tong, Hang Bui, Caitlin Spofford, and Hal S. Alper
      PNAS January 7, 2014 111 (1) 131-136; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1311970111
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      De novo selection of oncogenes
      Kelly M. Chacón, Lisa M. Petti, Elizabeth H. Scheideman, Valentina Pirazzoli, Katerina Politi, and Daniel DiMaio
      PNAS January 7, 2014 111 (1) E6-E14; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1315298111
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      AFF1 is a ubiquitous P-TEFb partner to enable Tat extraction of P-TEFb from 7SK snRNP and formation of SECs for HIV transactivation
      Huasong Lu, Zichong Li, Yuhua Xue, Ursula Schulze-Gahmen, Jeffrey R. Johnson, Nevan J. Krogan, Tom Alber, and Qiang Zhou
      PNAS January 7, 2014 111 (1) E15-E24; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1318503111
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      A Cdc42- and Rac-interactive binding (CRIB) domain mediates functions of coronin
      Karthic Swaminathan, Annette Müller-Taubenberger, Jan Faix, Francisco Rivero, and Angelika A. Noegel
      PNAS January 7, 2014 111 (1) E25-E33; published ahead of print December 17, 2013. https://doi.org/10.1073/pnas.1315368111
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      Parkinson-related LRRK2 mutation R1441C/G/H impairs PKA phosphorylation of LRRK2 and disrupts its interaction with 14-3-3
      Kathrin Muda, Daniela Bertinetti, Frank Gesellchen, Jennifer Sarah Hermann, Felix von Zweydorf, Arie Geerlof, Anette Jacob, Marius Ueffing, Christian Johannes Gloeckner, and Friedrich W. Herberg
      PNAS January 7, 2014 111 (1) E34-E43; published ahead of print December 18, 2013. https://doi.org/10.1073/pnas.1312701111
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      Pch2 is a hexameric ring ATPase that remodels the chromosome axis protein Hop1
      Cheng Chen, Ahmad Jomaa, Joaquin Ortega, and Eric E. Alani
      PNAS January 7, 2014 111 (1) E44-E53; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1310755111
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      Structural and biochemical basis for the inhibition of cell death by APIP, a methionine salvage enzyme
      Wonchull Kang, Se Hoon Hong, Hye Min Lee, Na Yeon Kim, Yun Chan Lim, Le Thi My Le, Bitna Lim, Hyun Chul Kim, Tae Yeon Kim, Hiroki Ashida, Akiho Yokota, Sang Soo Hah, Keun Ho Chun, Yong-Keun Jung, and Jin Kuk Yang
      PNAS January 7, 2014 111 (1) E54-E61; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1308768111
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      Rationale and mechanism for the low photoinactivation rate of bacteria in plasma
      Jie Chen, Thomas C. Cesario, and Peter M. Rentzepis
      PNAS January 7, 2014 111 (1) 33-38; published ahead of print December 24, 2013. https://doi.org/10.1073/pnas.1315053111
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      Structure of a eukaryotic thiaminase I
      Cheryl A. Kreinbring, Stephen P. Remillard, Paul Hubbard, Heather R. Brodkin, Finian J. Leeper, Dan Hawksley, Elaine Y. Lai, Chandler Fulton, Gregory A. Petsko, and Dagmar Ringe
      PNAS January 7, 2014 111 (1) 137-142; published ahead of print December 18, 2013. https://doi.org/10.1073/pnas.1315882110
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      Reaction-based fluorescent sensor for investigating mobile Zn2+ in mitochondria of healthy versus cancerous prostate cells
      Wen Chyan, Daniel Y. Zhang, Stephen J. Lippard, and Robert J. Radford
      PNAS January 7, 2014 111 (1) 143-148; published ahead of print December 12, 2013. https://doi.org/10.1073/pnas.1310583110
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      Quantum mechanical calculations suggest that lytic polysaccharide monooxygenases use a copper-oxyl, oxygen-rebound mechanism
      Seonah Kim, Jerry Ståhlberg, Mats Sandgren, Robert S. Paton, and Gregg T. Beckham
      PNAS January 7, 2014 111 (1) 149-154; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1316609111
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      Regulation of PTEN inhibition by the pleckstrin homology domain of P-REX2 during insulin signaling and glucose homeostasis
      Cindy Hodakoski, Benjamin D. Hopkins, Douglas Barrows, Sarah M. Mense, Megan Keniry, Karen E. Anderson, Philip A. Kern, Phillip T. Hawkins, Len R. Stephens, and Ramon Parsons
      PNAS January 7, 2014 111 (1) 155-160; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1213773111
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      Biological role of prolyl 3-hydroxylation in type IV collagen
      Elena Pokidysheva, Sergei Boudko, Janice Vranka, Keith Zientek, Kerry Maddox, Markus Moser, Reinhard Fässler, Jerry Ware, and Hans Peter Bächinger
      PNAS January 7, 2014 111 (1) 161-166; published ahead of print December 24, 2013. https://doi.org/10.1073/pnas.1307597111
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      Circadian clock-dependent and -independent rhythmic proteomes implement distinct diurnal functions in mouse liver
      Daniel Mauvoisin, Jingkui Wang, Céline Jouffe, Eva Martin, Florian Atger, Patrice Waridel, Manfredo Quadroni, Frédéric Gachon, and Felix Naef
      PNAS January 7, 2014 111 (1) 167-172; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1314066111
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      Covalent EGFR inhibitor analysis reveals importance of reversible interactions to potency and mechanisms of drug resistance
      Phillip A. Schwartz, Petr Kuzmic, James Solowiej, Simon Bergqvist, Ben Bolanos, Chau Almaden, Asako Nagata, Kevin Ryan, Junli Feng, Deepak Dalvie, John C. Kath, Meirong Xu, Revati Wani, and Brion William Murray
      PNAS January 7, 2014 111 (1) 173-178; published ahead of print December 17, 2013. https://doi.org/10.1073/pnas.1313733111
  • Biophysics and Computational Biology

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      Cooperative assembly of IFI16 filaments on dsDNA provides insights into host defense strategy
      Seamus R. Morrone, Tao Wang, Leeza M. Constantoulakis, Richard M. Hooy, Michael J. Delannoy, and Jungsan Sohn
      PNAS January 7, 2014 111 (1) E62-E71; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1313577111
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      SuperBiHelix method for predicting the pleiotropic ensemble of G-protein–coupled receptor conformations
      Jenelle K. Bray, Ravinder Abrol, William A. Goddard III, Bartosz Trzaskowski, and Caitlin E. Scott
      PNAS January 7, 2014 111 (1) E72-E78; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1321233111
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      BK channel opening involves side-chain reorientation of multiple deep-pore residues
      Xixi Chen, Jiusheng Yan, and Richard W. Aldrich
      PNAS January 7, 2014 111 (1) E79-E88; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1321697111
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      Initial stages of calcium uptake and mineral deposition in sea urchin embryos
      Netta Vidavsky, Sefi Addadi, Julia Mahamid, Eyal Shimoni, David Ben-Ezra, Muki Shpigel, Steve Weiner, and Lia Addadi
      PNAS January 7, 2014 111 (1) 39-44; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1312833110
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      Large effect of membrane tension on the fluid–solid phase transitions of two-component phosphatidylcholine vesicles
      Dong Chen and Maria M. Santore
      PNAS January 7, 2014 111 (1) 179-184; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1314993111
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      Transmembrane allosteric coupling of the gates in a potassium channel
      Benjamin J. Wylie, Manasi P. Bhate, and Ann E. McDermott
      PNAS January 7, 2014 111 (1) 185-190; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1319577110
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      Designed amyloid fibers as materials for selective carbon dioxide capture
      Dan Li, Hiroyasu Furukawa, Hexiang Deng, Cong Liu, Omar M. Yaghi, and David S. Eisenberg
      PNAS January 7, 2014 111 (1) 191-196; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1321797111
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      Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS
      Magdalena I. Ivanova, Stuart A. Sievers, Elizabeth L. Guenther, Lisa M. Johnson, Duane D. Winkler, Ahmad Galaleldeen, Michael R. Sawaya, P. John Hart, and David S. Eisenberg
      PNAS January 7, 2014 111 (1) 197-201; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1320786110
    • Open Access
      Automatic Classification of Cellular Expression by Nonlinear Stochastic Embedding (ACCENSE)
      Karthik Shekhar, Petter Brodin, Mark M. Davis, and Arup K. Chakraborty
      PNAS January 7, 2014 111 (1) 202-207; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1321405111
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      Morphological optimization for access to dual oxidants in biofilms
      Christopher P. Kempes, Chinweike Okegbe, Zwoisaint Mears-Clarke, Michael J. Follows, and Lars E. P. Dietrich
      PNAS January 7, 2014 111 (1) 208-213; published ahead of print December 12, 2013. https://doi.org/10.1073/pnas.1315521110
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      Structure of Est3 reveals a bimodal surface with differential roles in telomere replication
      Timsi Rao, Johnathan W. Lubin, Geoffrey S. Armstrong, Timothy M. Tucey, Victoria Lundblad, and Deborah S. Wuttke
      PNAS January 7, 2014 111 (1) 214-218; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1316453111
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      Measuring membrane protein stability under native conditions
      Yu-Chu Chang and James U. Bowie
      PNAS January 7, 2014 111 (1) 219-224; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1318576111
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      Direct observation of a transient ternary complex during IκBα-mediated dissociation of NF-κB from DNA
      Vera Alverdi, Byron Hetrick, Simpson Joseph, and Elizabeth A. Komives
      PNAS January 7, 2014 111 (1) 225-230; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1318115111
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      Heteromerization of PIP aquaporins affects their intrinsic permeability
      Agustín Yaneff, Lorena Sigaut, Mercedes Marquez, Karina Alleva, Lía Isabel Pietrasanta, and Gabriela Amodeo
      PNAS January 7, 2014 111 (1) 231-236; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1316537111
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      Protein structural ensembles are revealed by redefining X-ray electron density noise
      P. Therese Lang, James M. Holton, James S. Fraser, and Tom Alber
      PNAS January 7, 2014 111 (1) 237-242; published ahead of print December 20, 2013. https://doi.org/10.1073/pnas.1302823110
  • Cell Biology

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      Interplay of mevalonate and Hippo pathways regulates RHAMM transcription via YAP to modulate breast cancer cell motility
      Zhongyuan Wang, Yanping Wu, Haifeng Wang, Yangqing Zhang, Lin Mei, Xuexun Fang, Xudong Zhang, Fang Zhang, Hongbo Chen, Ying Liu, Yuyang Jiang, Shengnan Sun, Yi Zheng, Na Li, and Laiqiang Huang
      PNAS January 7, 2014 111 (1) E89-E98; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1319190110
    • You have access
      Nucleolin is important for Epstein–Barr virus nuclear antigen 1-mediated episome binding, maintenance, and transcription
      Ya-Lin Chen, Cheng-Der Liu, Chi-Ping Cheng, Bo Zhao, Hao-Jen Hsu, Chih-Long Shen, Shu-Jun Chiu, Elliott Kieff, and Chih-wen Peng
      PNAS January 7, 2014 111 (1) 243-248; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1321800111
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      Celastrol increases glucocerebrosidase activity in Gaucher disease by modulating molecular chaperones
      Chunzhang Yang, Cody L. Swallows, Chao Zhang, Jie Lu, Hongbin Xiao, Roscoe O. Brady, and Zhengping Zhuang
      PNAS January 7, 2014 111 (1) 249-254; published ahead of print December 18, 2013. https://doi.org/10.1073/pnas.1321341111
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      Identification of cancer initiating cells in K-Ras driven lung adenocarcinoma
      Sara Mainardi, Nieves Mijimolle, Sarah Francoz, Carolina Vicente-Dueñas, Isidro Sánchez-García, and Mariano Barbacid
      PNAS January 7, 2014 111 (1) 255-260; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1320383110
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      Enhanced stability of Mcl1, a prosurvival Bcl2 relative, blunts stress-induced apoptosis, causes male sterility, and promotes tumorigenesis
      Toru Okamoto, Leigh Coultas, Donald Metcalf, Mark F. van Delft, Stefan P. Glaser, Megumi Takiguchi, Andreas Strasser, Philippe Bouillet, Jerry M. Adams, and David C. S. Huang
      PNAS January 7, 2014 111 (1) 261-266; published ahead of print December 20, 2013. https://doi.org/10.1073/pnas.1321259110
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      A mechanism for retromer endosomal coat complex assembly with cargo
      Megan S. Harrison, Chia-Sui Hung, Ting-ting Liu, Romain Christiano, Tobias C. Walther, and Christopher G. Burd
      PNAS January 7, 2014 111 (1) 267-272; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1316482111
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      Evaluation of intramitochondrial ATP levels identifies G0/G1 switch gene 2 as a positive regulator of oxidative phosphorylation
      Hidetaka Kioka, Hisakazu Kato, Makoto Fujikawa, Osamu Tsukamoto, Toshiharu Suzuki, Hiromi Imamura, Atsushi Nakano, Shuichiro Higo, Satoru Yamazaki, Takashi Matsuzaki, Kazuaki Takafuji, Hiroshi Asanuma, Masanori Asakura, Tetsuo Minamino, Yasunori Shintani, Masasuke Yoshida, Hiroyuki Noji, Masafumi Kitakaze, Issei Komuro, Yoshihiro Asano, and Seiji Takashima
      PNAS January 7, 2014 111 (1) 273-278; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1318547111
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      JMJD5 regulates PKM2 nuclear translocation and reprograms HIF-1α–mediated glucose metabolism
      Hung-Jung Wang, Ya-Ju Hsieh, Wen-Chi Cheng, Chun-Pu Lin, Yu-shan Lin, So-Fang Yang, Chung-Ching Chen, Yoshihiro Izumiya, Jau-Song Yu, Hsing-Jien Kung, and Wen-Ching Wang
      PNAS January 7, 2014 111 (1) 279-284; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1311249111
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      Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair
      Helen Yu, Helen Pak, Ian Hammond-Martel, Mehdi Ghram, Amélie Rodrigue, Salima Daou, Haithem Barbour, Luc Corbeil, Josée Hébert, Elliot Drobetsky, Jean Yves Masson, Javier M. Di Noia, and El Bachir Affar
      PNAS January 7, 2014 111 (1) 285-290; published ahead of print December 17, 2013. https://doi.org/10.1073/pnas.1309085110
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      miR-218 opposes a critical RTK-HIF pathway in mesenchymal glioblastoma
      Lijoy K. Mathew, Nicolas Skuli, Vera Mucaj, Samuel S. Lee, Pascal O. Zinn, Pratheesh Sathyan, Hongxia Z. Imtiyaz, Zhongfa Zhang, Ramana V. Davuluri, Shilpa Rao, Sriram Venneti, Priti Lal, Justin D. Lathia, Jeremy N. Rich, Brian Keith, Andy J. Minn, and M. Celeste Simon
      PNAS January 7, 2014 111 (1) 291-296; published ahead of print December 24, 2013. https://doi.org/10.1073/pnas.1314341111
  • Ecology

    • Open Access
      Emerging predictable features of replicated biological invasion fronts
      Andrea Giometto, Andrea Rinaldo, Francesco Carrara, and Florian Altermatt
      PNAS January 7, 2014 111 (1) 297-301; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1321167110
    • Open Access
      Effects of genotypic and phenotypic variation on establishment are important for conservation, invasion, and infection biology
      Anders Forsman
      PNAS January 7, 2014 111 (1) 302-307; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1317745111
    • Open Access
      Interannual variation in land-use intensity enhances grassland multidiversity
      Eric Allan, Oliver Bossdorf, Carsten F. Dormann, Daniel Prati, Martin M. Gossner, Teja Tscharntke, Nico Blüthgen, Michaela Bellach, Klaus Birkhofer, Steffen Boch, Stefan Böhm, Carmen Börschig, Antonis Chatzinotas, Sabina Christ, Rolf Daniel, Tim Diekötter, Christiane Fischer, Thomas Friedl, Karin Glaser, Christine Hallmann, Ladislav Hodac, Norbert Hölzel, Kirsten Jung, Alexandra Maria Klein, Valentin H. Klaus, Till Kleinebecker, Jochen Krauss, Markus Lange, E. Kathryn Morris, Jörg Müller, Heiko Nacke, Esther Pašalić, Matthias C. Rillig, Christoph Rothenwöhrer, Peter Schall, Christoph Scherber, Waltraud Schulze, Stephanie A. Socher, Juliane Steckel, Ingolf Steffan-Dewenter, Manfred Türke, Christiane N. Weiner, Michael Werner, Catrin Westphal, Volkmar Wolters, Tesfaye Wubet, Sonja Gockel, Martin Gorke, Andreas Hemp, Swen C. Renner, Ingo Schöning, Simone Pfeiffer, Birgitta König-Ries, François Buscot, Karl Eduard Linsenmair, Ernst-Detlef Schulze, Wolfgang W. Weisser, and Markus Fischer
      PNAS January 7, 2014 111 (1) 308-313; published ahead of print December 24, 2013. https://doi.org/10.1073/pnas.1312213111
  • Evolution

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      Drastic neofunctionalization associated with evolution of the timezyme AANAT 500 Mya
      Jack Falcón, Steven L. Coon, Laurence Besseau, Damien Cazaméa-Catalan, Michaël Fuentès, Elodie Magnanou, Charles-Hubert Paulin, Gilles Boeuf, Sandrine Sauzet, Even H. Jørgensen, Sylvie Mazan, Yuri I. Wolf, Eugene V. Koonin, Peter J. Steinbach, Susumu Hyodo, and David C. Klein
      PNAS January 7, 2014 111 (1) 314-319; published ahead of print December 18, 2013. https://doi.org/10.1073/pnas.1312634110
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      Aphid amino acid transporter regulates glutamine supply to intracellular bacterial symbionts
      Daniel R. G. Price, Honglin Feng, James D. Baker, Selvan Bavan, Charles W. Luetje, and Alex C. C. Wilson
      PNAS January 7, 2014 111 (1) 320-325; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1306068111
    • Open Access
      Policing of reproduction by hidden threats in a cooperative mammal
      • From the Cover
      Michael A. Cant, Hazel J. Nichols, Rufus A. Johnstone, and Sarah J. Hodge
      PNAS January 7, 2014 111 (1) 326-330; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1312626111
    • Open Access
      A unique covalent bond in basement membrane is a primordial innovation for tissue evolution
      Aaron L. Fidler, Roberto M. Vanacore, Sergei V. Chetyrkin, Vadim K. Pedchenko, Gautam Bhave, Viravuth P. Yin, Cody L. Stothers, Kristie Lindsey Rose, W. Hayes McDonald, Travis A. Clark, Dorin-Bogdan Borza, Robert E. Steele, Michael T. Ivy, The Aspirnauts, Julie K. Hudson, and Billy G. Hudson
      PNAS January 7, 2014 111 (1) 331-336; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1318499111
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      PIWI proteins and PIWI-interacting RNAs function in Hydra somatic stem cells
      Celina E. Juliano, Adrian Reich, Na Liu, Jessica Götzfried, Mei Zhong, Selen Uman, Robert A. Reenan, Gary M. Wessel, Robert E. Steele, and Haifan Lin
      PNAS January 7, 2014 111 (1) 337-342; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1320965111
  • Genetics

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      FMRP and Ataxin-2 function together in long-term olfactory habituation and neuronal translational control
      Indulekha P. Sudhakaran, Jens Hillebrand, Adrian Dervan, Sudeshna Das, Eimear E. Holohan, Jörn Hülsmeier, Mihail Sarov, Roy Parker, K. VijayRaghavan, and Mani Ramaswami
      PNAS January 7, 2014 111 (1) E99-E108; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1309543111
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      Scan statistic-based analysis of exome sequencing data identifies FAN1 at 15q13.3 as a susceptibility gene for schizophrenia and autism
      Iuliana Ionita-Laza, Bin Xu, Vlad Makarov, Joseph D. Buxbaum, J. Louw Roos, Joseph A. Gogos, and Maria Karayiorgou
      PNAS January 7, 2014 111 (1) 343-348; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1309475110
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      Quantitation of the DNA tethering effect in long-range DNA looping in vivo and in vitro using the Lac and λ repressors
      David G. Priest, Lun Cui, Sandip Kumar, David D. Dunlap, Ian B. Dodd, and Keith E. Shearwin
      PNAS January 7, 2014 111 (1) 349-354; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1317817111
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      Contribution of phenotypic heterogeneity to adaptive antibiotic resistance
      María Antonia Sánchez-Romero and Josep Casadesús
      PNAS January 7, 2014 111 (1) 355-360; published ahead of print December 18, 2013. https://doi.org/10.1073/pnas.1316084111
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      Ohnologs are overrepresented in pathogenic copy number mutations
      Aoife McLysaght, Takashi Makino, Hannah M. Grayton, Maria Tropeano, Kevin J. Mitchell, Evangelos Vassos, and David A. Collier
      PNAS January 7, 2014 111 (1) 361-366; published ahead of print December 24, 2013. https://doi.org/10.1073/pnas.1309324111
  • Immunology

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      Trapping of naive lymphocytes triggers rapid growth and remodeling of the fibroblast network in reactive murine lymph nodes
      Chen-Ying Yang, Tobias K. Vogt, Stéphanie Favre, Leonardo Scarpellino, Hsin-Ying Huang, Fabienne Tacchini-Cottier, and Sanjiv A. Luther
      PNAS January 7, 2014 111 (1) E109-E118; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1312585111
    • Open Access
      Effective functional maturation of invariant natural killer T cells is constrained by negative selection and T-cell antigen receptor affinity
      Romain Bedel, Richard Berry, Thierry Mallevaey, Jennifer L. Matsuda, Jingjing Zhang, Dale I. Godfrey, Jamie Rossjohn, John W. Kappler, Philippa Marrack, and Laurent Gapin
      PNAS January 7, 2014 111 (1) E119-E128; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1320777110
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      IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis
      Emily Hams, Michelle E. Armstrong, Jillian L. Barlow, Sean P. Saunders, Christian Schwartz, Gordon Cooke, Ruairi J. Fahy, Thomas B. Crotty, Nikhil Hirani, Robin J. Flynn, David Voehringer, Andrew N. J. McKenzie, Seamas C. Donnelly, and Padraic G. Fallon
      PNAS January 7, 2014 111 (1) 367-372; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1315854111
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      Altered inactivation of commensal LPS due to acyloxyacyl hydrolase deficiency in colonic dendritic cells impairs mucosal Th17 immunity
      Brian M. Janelsins, Mingfang Lu, and Sandip K. Datta
      PNAS January 7, 2014 111 (1) 373-378; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1311987111
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      Dynamic control of β1 integrin adhesion by the plexinD1-sema3E axis
      Young I. Choi, Jonathan S. Duke-Cohan, Wei Chen, Baoyu Liu, Jérémie Rossy, Thibault Tabarin, Lining Ju, Jingang Gui, Katharina Gaus, Cheng Zhu, and Ellis L. Reinherz
      PNAS January 7, 2014 111 (1) 379-384; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1314209111
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      Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection
      Md. Hasan Zaki, Si Ming Man, Peter Vogel, Mohamed Lamkanfi, and Thirumala-Devi Kanneganti
      PNAS January 7, 2014 111 (1) 385-390; published ahead of print December 17, 2013. https://doi.org/10.1073/pnas.1317643111
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      β-Catenin induces T-cell transformation by promoting genomic instability
      Marei Dose, Akinola Olumide Emmanuel, Julie Chaumeil, Jiangwen Zhang, Tianjiao Sun, Kristine Germar, Katayoun Aghajani, Elizabeth M. Davis, Shilpa Keerthivasan, Andrea L. Bredemeyer, Barry P. Sleckman, Steven T. Rosen, Jane A. Skok, Michelle M. Le Beau, Katia Georgopoulos, and Fotini Gounari
      PNAS January 7, 2014 111 (1) 391-396; published ahead of print December 26, 2013. https://doi.org/10.1073/pnas.1315752111
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      An amphioxus RAG1-like DNA fragment encodes a functional central domain of vertebrate core RAG1
      Yanni Zhang, Ke Xu, Anqi Deng, Xing Fu, Anlong Xu, and Xiaolong Liu
      PNAS January 7, 2014 111 (1) 397-402; published ahead of print December 24, 2013. https://doi.org/10.1073/pnas.1318843111
    • Open Access
      Alloreactive cytotoxic T cells provide means to decipher the immunopeptidome and reveal a plethora of tumor-associated self-epitopes
      Shraddha Kumari, Sébastien Wälchli, Lars-Egil Fallang, Weiwen Yang, Fridtjof Lund-Johansen, Ton N. Schumacher, and Johanna Olweus
      PNAS January 7, 2014 111 (1) 403-408; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1306549111
  • Medical Sciences

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      Cytoglobin modulates myogenic progenitor cell viability and muscle regeneration
      Sarvjeet Singh, Diana C. Canseco, Shilpa M. Manda, John M. Shelton, Rajendra R. Chirumamilla, Sean C. Goetsch, Qiu Ye, Robert D. Gerard, Jay W. Schneider, James A. Richardson, Beverly A. Rothermel, and Pradeep P. A. Mammen
      PNAS January 7, 2014 111 (1) E129-E138; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1314962111
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      mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy
      Markus Weiler, Jonas Blaes, Stefan Pusch, Felix Sahm, Marcus Czabanka, Sebastian Luger, Lukas Bunse, Gergely Solecki, Viktoria Eichwald, Manfred Jugold, Sibylle Hodecker, Matthias Osswald, Christoph Meisner, Thomas Hielscher, Petra Rübmann, Philipp-Niklas Pfenning, Michael Ronellenfitsch, Tore Kempf, Martina Schnölzer, Amir Abdollahi, Florian Lang, Martin Bendszus, Andreas von Deimling, Frank Winkler, Michael Weller, Peter Vajkoczy, Michael Platten, and Wolfgang Wick
      PNAS January 7, 2014 111 (1) 409-414; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1314469111
    • Open Access
      Dual-modality gene reporter for in vivo imaging
      P. Stephen Patrick, Jayne Hammersley, Louiza Loizou, Mikko I. Kettunen, Tiago B. Rodrigues, De-En Hu, Sui-Seng Tee, Robin Hesketh, Scott K. Lyons, Dmitry Soloviev, David Y. Lewis, Silvio Aime, Sandra M. Fulton, and Kevin M. Brindle
      PNAS January 7, 2014 111 (1) 415-420; published ahead of print December 17, 2013. https://doi.org/10.1073/pnas.1319000111
  • Microbiology

    • Open Access
      Microbial biogeography of wine grapes is conditioned by cultivar, vintage, and climate
      • From the Cover
      Nicholas A. Bokulich, John H. Thorngate, Paul M. Richardson, and David A. Mills
      PNAS January 7, 2014 111 (1) E139-E148; published ahead of print November 25, 2013. https://doi.org/10.1073/pnas.1317377110
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      Epstein–Barr Virus Nuclear Antigen 3C binds to BATF/IRF4 or SPI1/IRF4 composite sites and recruits Sin3A to repress CDKN2A
      Sizun Jiang, Bradford Willox, Hufeng Zhou, Amy M. Holthaus, Anqi Wang, Tommy T. Shi, Seiji Maruo, Peter V. Kharchenko, Eric C. Johannsen, Elliott Kieff, and Bo Zhao
      PNAS January 7, 2014 111 (1) 421-426; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1321704111
    • Open Access
      Neisseria meningitidis NalP cleaves human complement C3, facilitating degradation of C3b and survival in human serum
      Elena Del Tordello, Irene Vacca, Sanjay Ram, Rino Rappuoli, and Davide Serruto
      PNAS January 7, 2014 111 (1) 427-432; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1321556111
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      Identification of secreted bacterial proteins by noncanonical amino acid tagging
      Alborz Mahdavi, Janek Szychowski, John T. Ngo, Michael J. Sweredoski, Robert L. J. Graham, Sonja Hess, Olaf Schneewind, Sarkis K. Mazmanian, and David A. Tirrell
      PNAS January 7, 2014 111 (1) 433-438; published ahead of print December 17, 2013. https://doi.org/10.1073/pnas.1301740111
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      Mathematical modeling of primary succession of murine intestinal microbiota
      Simeone Marino, Nielson T. Baxter, Gary B. Huffnagle, Joseph F. Petrosino, and Patrick D. Schloss
      PNAS January 7, 2014 111 (1) 439-444; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1311322111
    • Open Access
      A common solution to group 2 influenza virus neutralization
      Robert H. E. Friesen, Peter S. Lee, Esther J. M. Stoop, Ryan M. B. Hoffman, Damian C. Ekiert, Gira Bhabha, Wenli Yu, Jarek Juraszek, Wouter Koudstaal, Mandy Jongeneelen, Hans J. W. M. Korse, Carla Ophorst, Els C. M. Brinkman-van der Linden, Mark Throsby, Mark J. Kwakkenbos, Arjen Q. Bakker, Tim Beaumont, Hergen Spits, Ted Kwaks, Ronald Vogels, Andrew B. Ward, Jaap Goudsmit, and Ian A. Wilson
      PNAS January 7, 2014 111 (1) 445-450; published ahead of print December 11, 2013. https://doi.org/10.1073/pnas.1319058110
    • Open Access
      Human herpesvirus 6 (HHV-6) alters E2F1/Rb pathways and utilizes the E2F1 transcription factor to express viral genes
      Eyal Sharon, Ludmila Volchek, and Niza Frenkel
      PNAS January 7, 2014 111 (1) 451-456; published ahead of print December 12, 2013. https://doi.org/10.1073/pnas.1308854110
    • Open Access
      The antigen 43 structure reveals a molecular Velcro-like mechanism of autotransporter-mediated bacterial clumping
      Begoña Heras, Makrina Totsika, Kate M. Peters, Jason J. Paxman, Christine L. Gee, Russell J. Jarrott, Matthew A. Perugini, Andrew E. Whitten, and Mark A. Schembri
      PNAS January 7, 2014 111 (1) 457-462; published ahead of print December 13, 2013. https://doi.org/10.1073/pnas.1311592111
  • Neuroscience

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      Ghrelin triggers the synaptic incorporation of AMPA receptors in the hippocampus
      Luís F. Ribeiro, Tatiana Catarino, Sandra D. Santos, Marion Benoist, J. Fiona van Leeuwen, José A. Esteban, and Ana Luísa Carvalho
      PNAS January 7, 2014 111 (1) E149-E158; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1313798111
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      Origins of R2∗ orientation dependence in gray and white matter
      David A. Rudko, L. Martyn Klassen, Sonali N. de Chickera, Joseph S. Gati, Gregory A. Dekaban, and Ravi S. Menon
      PNAS January 7, 2014 111 (1) E159-E167; published ahead of print December 27, 2013. https://doi.org/10.1073/pnas.1306516111
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      Dual role for Islet-1 in promoting striatonigral and repressing striatopallidal genetic programs to specify striatonigral cell identity
      Kuan-Ming Lu, Sylvia M. Evans, Shinji Hirano, and Fu-Chin Liu
      PNAS January 7, 2014 111 (1) E168-E177; published ahead of print December 18, 2013. https://doi.org/10.1073/pnas.1319138111
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      Cortical neural populations can guide behavior by integrating inputs linearly, independent of synchrony
      Mark H. Histed and John H. R. Maunsell
      PNAS January 7, 2014 111 (1) E178-E187; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1318750111
    • Open Access
      Distinct cerebellar engrams in short-term and long-term motor learning
      Wen Wang, Kazuhiko Nakadate, Miwako Masugi-Tokita, Fumihiro Shutoh, Wajeeha Aziz, Etsuko Tarusawa, Andrea Lorincz, Elek Molnár, Sebnem Kesaf, Yun-Qing Li, Yugo Fukazawa, Soichi Nagao, and Ryuichi Shigemoto
      PNAS January 7, 2014 111 (1) E188-E193; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1315541111
    • Open Access
      Distinct kinetics of synaptic structural plasticity, memory formation, and memory decay in massed and spaced learning
      Wajeeha Aziz, Wen Wang, Sebnem Kesaf, Alsayed Abdelhamid Mohamed, Yugo Fukazawa, and Ryuichi Shigemoto
      PNAS January 7, 2014 111 (1) E194-E202; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1303317110
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      High-resolution photoacoustic tomography of resting-state functional connectivity in the mouse brain
      Mohammadreza Nasiriavanaki, Jun Xia, Hanlin Wan, Adam Quentin Bauer, Joseph P. Culver, and Lihong V. Wang
      PNAS January 7, 2014 111 (1) 21-26; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1311868111
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      Local domains of motor cortical activity revealed by fiber-optic calcium recordings in behaving nonhuman primates
      Helmuth Adelsberger, Antonio Zainos, Manuel Alvarez, Ranulfo Romo, and Arthur Konnerth
      PNAS January 7, 2014 111 (1) 463-468; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1321612111
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      Protein kinase LKB1 regulates polarized dendrite formation of adult hippocampal newborn neurons
      Wei Huang, Liang She, Xing-ya Chang, Rong-rong Yang, Liang Wang, Hong-bin Ji, Jian-wei Jiao, and Mu-ming Poo
      PNAS January 7, 2014 111 (1) 469-474; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1321454111
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      Comparison of explicit and incidental learning strategies in memory-impaired patients
      Christine N. Smith, Zhisen J. Urgolites, Ramona O. Hopkins, and Larry R. Squire
      PNAS January 7, 2014 111 (1) 475-479; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1322263111
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      Representation of interval timing by temporally scalable firing patterns in rat prefrontal cortex
      Min Xu, Si-yu Zhang, Yang Dan, and Mu-ming Poo
      PNAS January 7, 2014 111 (1) 480-485; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1321314111
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      Presynaptic mitochondrial morphology in monkey prefrontal cortex correlates with working memory and is improved with estrogen treatment
      • From the Cover
      Yuko Hara, Frank Yuk, Rishi Puri, William G. M. Janssen, Peter R. Rapp, and John H. Morrison
      PNAS January 7, 2014 111 (1) 486-491; published ahead of print December 2, 2013. https://doi.org/10.1073/pnas.1311310110
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      Bidirectional homeostatic plasticity induced by interneuron cell death and transplantation in vivo
      MacKenzie Allen Howard, John L. R. Rubenstein, and Scott C. Baraban
      PNAS January 7, 2014 111 (1) 492-497; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1307784111
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      Mechanisms underlying subunit independence in pyramidal neuron dendrites
      Bardia F. Behabadi and Bartlett W. Mel
      PNAS January 7, 2014 111 (1) 498-503; published ahead of print December 19, 2013. https://doi.org/10.1073/pnas.1217645111
    • Open Access
      Tonic GABAA conductance bidirectionally controls interneuron firing pattern and synchronization in the CA3 hippocampal network
      Ivan Pavlov, Leonid P. Savtchenko, Inseon Song, Jaeyeon Koo, Alexey Pimashkin, Dmitri A. Rusakov, and Alexey Semyanov
      PNAS January 7, 2014 111 (1) 504-509; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1308388110
    • Open Access
      Neurofibrillary tangle-bearing neurons are functionally integrated in cortical circuits in vivo
      Kishore V. Kuchibhotla, Susanne Wegmann, Katherine J. Kopeikina, Jonathan Hawkes, Nikita Rudinskiy, Mark L. Andermann, Tara L. Spires-Jones, Brian J. Bacskai, and Bradley T. Hyman
      PNAS January 7, 2014 111 (1) 510-514; published ahead of print December 24, 2013. https://doi.org/10.1073/pnas.1318807111
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      Cumulative latency advance underlies fast visual processing in desynchronized brain state
      Xu-dong Wang, Cheng Chen, Dinghong Zhang, and Haishan Yao
      PNAS January 7, 2014 111 (1) 515-520; published ahead of print December 17, 2013. https://doi.org/10.1073/pnas.1316166111
  • Physiology

    • Open Access
      Optical control of trimeric P2X receptors and acid-sensing ion channels
      Liam E. Browne, João P. M. Nunes, Joan A. Sim, Vijay Chudasama, Laricia Bragg, Stephen Caddick, and R. Alan North
      PNAS January 7, 2014 111 (1) 521-526; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1318582111
  • Plant Biology

    • Open Access
      Translational dynamics revealed by genome-wide profiling of ribosome footprints in Arabidopsis
      Piyada Juntawong, Thomas Girke, Jérémie Bazin, and Julia Bailey-Serres
      PNAS January 7, 2014 111 (1) E203-E212; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1317811111
    • You have access
      Arabidopsis EDM2 promotes IBM1 distal polyadenylation and regulates genome DNA methylation patterns
      • From the Cover
      Mingguang Lei, Honggui La, Kun Lu, Pengcheng Wang, Daisuke Miki, Zhizhong Ren, Cheng-Guo Duan, Xingang Wang, Kai Tang, Liang Zeng, Lan Yang, Heng Zhang, Wenfeng Nie, Pan Liu, Jianping Zhou, Renyi Liu, Yingli Zhong, Dong Liu, and Jian-Kang Zhu
      PNAS January 7, 2014 111 (1) 527-532; published ahead of print November 18, 2013. https://doi.org/10.1073/pnas.1320106110
    • Open Access
      Overexpression of plasma membrane H+-ATPase in guard cells promotes light-induced stomatal opening and enhances plant growth
      Yin Wang, Ko Noguchi, Natsuko Ono, Shin-ichiro Inoue, Ichiro Terashima, and Toshinori Kinoshita
      PNAS January 7, 2014 111 (1) 533-538; published ahead of print December 23, 2013. https://doi.org/10.1073/pnas.1305438111
  • Sustainability Science

    • Open Access
      Data-poor management of African lion hunting using a relative index of abundance
      Charles T. T. Edwards, Nils Bunnefeld, Guy A. Balme, and E. J. Milner-Gulland
      PNAS January 7, 2014 111 (1) 539-543; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1219615110
  • Systems Biology

    • Open Access
      Critical slowing down as early warning for the onset and termination of depression
      • From the Cover
      Ingrid A. van de Leemput, Marieke Wichers, Angélique O. J. Cramer, Denny Borsboom, Francis Tuerlinckx, Peter Kuppens, Egbert H. van Nes, Wolfgang Viechtbauer, Erik J. Giltay, Steven H. Aggen, Catherine Derom, Nele Jacobs, Kenneth S. Kendler, Han L. J. van der Maas, Michael C. Neale, Frenk Peeters, Evert Thiery, Peter Zachar, and Marten Scheffer
      PNAS January 7, 2014 111 (1) 87-92; published ahead of print December 9, 2013. https://doi.org/10.1073/pnas.1312114110
    • You have access
      Growth feedback as a basis for persister bistability
      Jingchen Feng, David A. Kessler, Eshel Ben-Jacob, and Herbert Levine
      PNAS January 7, 2014 111 (1) 544-549; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1320396110
    • You have access
      Identification of key regulators for the migration and invasion of rheumatoid synoviocytes through a systems approach
      Sungyong You, Seung-Ah Yoo, Susanna Choi, Ji-Young Kim, Su-Jung Park, Jong Dae Ji, Tae-Hwan Kim, Ki-Jo Kim, Chul-Soo Cho, Daehee Hwang, and Wan-Uk Kim
      PNAS January 7, 2014 111 (1) 550-555; published ahead of print December 27, 2013. https://doi.org/10.1073/pnas.1311239111
    • Open Access
      Direct observation of single stationary-phase bacteria reveals a surprisingly long period of constant protein production activity
      Orit Gefen, Ofer Fridman, Irine Ronin, and Nathalie Q. Balaban
      PNAS January 7, 2014 111 (1) 556-561; published ahead of print December 16, 2013. https://doi.org/10.1073/pnas.1314114111

Corrections

  • You have access
    Correction for Kirkpatrick et al., Phosphoproteomic characterization of DNA damage response in melanoma cells following MEK/PI3K dual inhibition
    PNAS January 7, 2014 111 (1) 562-563; published ahead of print December 17, 2013. https://doi.org/10.1073/pnas.1322630111
  • You have access
    Correction for Tisserant et al., Genome of an arbuscular mycorrhizal fungus provides insight into the oldest plant symbiosis
    PNAS January 7, 2014 111 (1) 562-563; published ahead of print December 20, 2013. https://doi.org/10.1073/pnas.1322697111
  • You have access
    Correction for Gartner et al., Whole-genome sequencing identifies a recurrent functional synonymous mutation in melanoma
    PNAS January 7, 2014 111 (1) 562-563; published ahead of print December 20, 2013. https://doi.org/10.1073/pnas.1323160111
  • You have access
    Correction for Shibue and Weinberg, Integrin β1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs
    PNAS January 7, 2014 111 (1) 562-563; published ahead of print December 17, 2013. https://doi.org/10.1073/pnas.1322177111
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Proceedings of the National Academy of Sciences: 111 (1)
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