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Table of Contents
April 22, 2014; vol. 111 no. 16
This Week in PNAS
PNAS 100th Anniversary Articles
Editorial
Commentary
- You have accessThe RNA code: Nature’s Rosetta StoneC. Thomas Caskey and Philip Leder
See companion article:
- The genetic code- Apr 22, 2014
See companion article:
Letters (Online Only)
- You have accessTesting the validity of ensemble descriptions of intrinsically disordered proteinsMalene Ringkjøbing Jensen and Martin BlackledgePNAS April 22, 2014 111 (16) E1557-E1558; first published March 17, 2014. https://doi.org/10.1073/pnas.1323876111
- You have accessReply to Jensen and Blackledge: Dual quantifications of intrinsically disordered proteins by NMR ensembles and molecular dynamics simulationsYong Wang, Sonia Longhi, Philippe Roche, and Jin WangPNAS April 22, 2014 111 (16) E1559; first published March 17, 2014. https://doi.org/10.1073/pnas.1400340111
See companion article:
- Coupled folding and binding of the α-MoRE of NTAIL- Sep 16, 2013
- You have accessRisks of double-counting in deep sequencingMichael W. Schmitt, Edward J. Fox, and Jesse J. SalkPNAS April 22, 2014 111 (16) E1560; first published March 20, 2014. https://doi.org/10.1073/pnas.1400941111
- You have accessReply to Schmitt et al.: Data-filtering schemes for avoiding double-counting in circle sequencingJeffrey A. Hussmann, Dianne I. Lou, Sara L. Sawyer, and William H. PressPNAS April 22, 2014 111 (16) E1561; first published March 20, 2014. https://doi.org/10.1073/pnas.1402606111
See companion article:
- Sequencing errors reduced by circle sequencing- Nov 15, 2013
Inner Workings
An over-the-shoulder look at scientists at work.
- You have accessThe genetic code
- Front Matter
Jessica MarshallSee companion article:
- The RNA code: Nature’s Rosetta Stone- Apr 22, 2014
QnAs
- You have accessQnAs with Victor DzauPrashant NairPNAS April 22, 2014 111 (16) 5761-5762; first published April 7, 2014. https://doi.org/10.1073/pnas.1405094111
PNAS Plus Significance Statements
Brief statements written by the authors about the significance of their papers.
Perspective
- You have accessRescuing US biomedical research from its systemic flawsBruce Alberts, Marc W. Kirschner, Shirley Tilghman, and Harold VarmusPNAS April 22, 2014 111 (16) 5773-5777; first published April 14, 2014. https://doi.org/10.1073/pnas.1404402111
Physical Sciences
Applied Physical Sciences
- Open AccessBending forces plastically deform growing bacterial cell wallsAriel Amir, Farinaz Babaeipour, Dustin B. McIntosh, David R. Nelson, and Suckjoon JunPNAS April 22, 2014 111 (16) 5778-5783; first published April 7, 2014. https://doi.org/10.1073/pnas.1317497111
- You have accessSuperwetting of TiO2 by light-induced water-layer growth via delocalized surface electronsKunyoung Lee, QHwan Kim, Sangmin An, JeongHoon An, Jongwoo Kim, Bongsu Kim, and Wonho JhePNAS April 22, 2014 111 (16) 5784-5789; first published April 7, 2014. https://doi.org/10.1073/pnas.1319001111
- Open AccessRenormalization of myoglobin–ligand binding energetics by quantum many-body effectsCédric Weber, Daniel J. Cole, David D. O’Regan, and Mike C. PaynePNAS April 22, 2014 111 (16) 5790-5795; first published April 9, 2014. https://doi.org/10.1073/pnas.1322966111
Chemistry
- You have accessStructural motif of polyglutamine amyloid fibrils discerned with mixed-isotope infrared spectroscopyLauren E. Buchanan, Joshua K. Carr, Aaron M. Fluitt, Andrew J. Hoganson, Sean D. Moran, Juan J. de Pablo, James L. Skinner, and Martin T. ZanniPNAS April 22, 2014 111 (16) 5796-5801; first published February 18, 2014. https://doi.org/10.1073/pnas.1401587111
Earth, Atmospheric, and Planetary Sciences
- Open AccessInfluence of vapor wall loss in laboratory chambers on yields of secondary organic aerosolXuan Zhang, Christopher D. Cappa, Shantanu H. Jathar, Renee C. McVay, Joseph J. Ensberg, Michael J. Kleeman, and John H. SeinfeldPNAS April 22, 2014 111 (16) 5802-5807; first published April 7, 2014. https://doi.org/10.1073/pnas.1404727111
- You have accessNitrogen isotopes in ice core nitrate linked to anthropogenic atmospheric acidity changeLei Geng, Becky Alexander, Jihong Cole-Dai, Eric J. Steig, Joël Savarino, Eric D. Sofen, and Andrew J. SchauerPNAS April 22, 2014 111 (16) 5808-5812; first published April 7, 2014. https://doi.org/10.1073/pnas.1319441111
Engineering
- You have accessCharacterizing asthma from a drop of blood using neutrophil chemotaxisEric Karl-Heinz Sackmann, Erwin Berthier, Elizabeth A. Schwantes, Paul S. Fichtinger, Michael D. Evans, Laura L. Dziadzio, Anna Huttenlocher, Sameer K. Mathur, and David J. BeebePNAS April 22, 2014 111 (16) 5813-5818; first published April 7, 2014. https://doi.org/10.1073/pnas.1324043111
Environmental Sciences
- You have accessChanges in peat chemistry associated with permafrost thaw increase greenhouse gas productionSuzanne B. Hodgkins, Malak M. Tfaily, Carmody K. McCalley, Tyler A. Logan, Patrick M. Crill, Scott R. Saleska, Virginia I. Rich, and Jeffrey P. ChantonPNAS April 22, 2014 111 (16) 5819-5824; first published April 7, 2014. https://doi.org/10.1073/pnas.1314641111
Physics
- You have accessConcurrence of monoenergetic electron beams and bright X-rays from an evolving laser-plasma bubbleWenchao Yan, Liming Chen, Dazhang Li, Lu Zhang, Nasr A. M. Hafz, James Dunn, Yong Ma, Kai Huang, Luning Su, Min Chen, Zhengming Sheng, and Jie ZhangPNAS April 22, 2014 111 (16) 5825-5830; first published April 7, 2014. https://doi.org/10.1073/pnas.1404336111
- You have accessColloidal aggregation and dynamics in anisotropic fluidsFrédéric Mondiot, Robert Botet, Patrick Snabre, Olivier Mondain-Monval, and Jean-Christophe LoudetPNAS April 22, 2014 111 (16) 5831-5836; first published April 8, 2014. https://doi.org/10.1073/pnas.1321903111
Social Sciences
Psychological and Cognitive Sciences
- You have accessLanguage universals at birthDavid Maximiliano Gómez, Iris Berent, Silvia Benavides-Varela, Ricardo A. H. Bion, Luigi Cattarossi, Marina Nespor, and Jacques MehlerPNAS April 22, 2014 111 (16) 5837-5841; first published March 31, 2014. https://doi.org/10.1073/pnas.1318261111
- You have accessLanguage learners privilege structured meaning over surface frequencyJennifer Culbertson and David AdgerPNAS April 22, 2014 111 (16) 5842-5847; first published March 31, 2014. https://doi.org/10.1073/pnas.1320525111
- Open AccessSocial disadvantage, genetic sensitivity, and children’s telomere lengthColter Mitchell, John Hobcraft, Sara S. McLanahan, Susan Rutherford Siegel, Arthur Berg, Jeanne Brooks-Gunn, Irwin Garfinkel, and Daniel NottermanPNAS April 22, 2014 111 (16) 5944-5949; first published April 7, 2014. https://doi.org/10.1073/pnas.1404293111
See companion article:
- Reply to Drury and Theall: No stratification- Jun 02, 2014
- You have accessDrinking alcohol has sex-dependent effects on pair bond formation in prairie volesAllison M. J. Anacker, Todd H. Ahern, Caroline M. Hostetler, Brett D. Dufour, Monique L. Smith, Davelle L. Cocking, Ju Li, Larry J. Young, Jennifer M. Loftis, and Andrey E. RyabininPNAS April 22, 2014 111 (16) 6052-6057; first published April 7, 2014. https://doi.org/10.1073/pnas.1320879111
Biological Sciences
Anthropology
- You have accessContinuity of mammalian fauna over the last 200,000 y in the Indian subcontinentPatrick Roberts, Eric Delson, Preston Miracle, Peter Ditchfield, Richard G. Roberts, Zenobia Jacobs, James Blinkhorn, Russell L. Ciochon, John G. Fleagle, Stephen R. Frost, Christopher C. Gilbert, Gregg F. Gunnell, Terry Harrison, Ravi Korisettar, and Michael D. PetragliaPNAS April 22, 2014 111 (16) 5848-5853; first published April 7, 2014. https://doi.org/10.1073/pnas.1323465111
Applied Biological Sciences
- Open AccessMating activates the heme peroxidase HPX15 in the sperm storage organ to ensure fertility in Anopheles gambiaeW. Robert Shaw, Eleonora Teodori, Sara N. Mitchell, Francesco Baldini, Paolo Gabrieli, David W. Rogers, and Flaminia CatterucciaPNAS April 22, 2014 111 (16) 5854-5859; first published April 7, 2014. https://doi.org/10.1073/pnas.1401715111
Biochemistry
- You have accessThe structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicityGeorg K. A. Hochberg, Heath Ecroyd, Cong Liu, Dezerae Cox, Duilio Cascio, Michael R. Sawaya, Miranda P. Collier, James Stroud, John A. Carver, Andrew J. Baldwin, Carol V. Robinson, David S. Eisenberg, Justin L. P. Benesch, and Arthur LaganowskyPNAS April 22, 2014 111 (16) E1562-E1570; first published April 7, 2014. https://doi.org/10.1073/pnas.1322673111
- You have accessRegulation of microtubule minus-end dynamics by CAMSAPs and PatroninMelissa C. Hendershott and Ronald D. ValePNAS April 22, 2014 111 (16) 5860-5865; first published March 26, 2014. https://doi.org/10.1073/pnas.1404133111
- You have accessCandida albicans SOD5 represents the prototype of an unprecedented class of Cu-only superoxide dismutases required for pathogen defenseJulie E. Gleason, Ahmad Galaleldeen, Ryan L. Peterson, Alexander B. Taylor, Stephen P. Holloway, Jessica Waninger-Saroni, Brendan P. Cormack, Diane E. Cabelli, P. John Hart, and Valeria Cizewski CulottaPNAS April 22, 2014 111 (16) 5866-5871; first published April 7, 2014. https://doi.org/10.1073/pnas.1400137111
- You have accessStructural basis for the evolution of vancomycin resistance D,D-peptidasesDjalal Meziane-Cherif, Peter J. Stogios, Elena Evdokimova, Alexei Savchenko, and Patrice CourvalinPNAS April 22, 2014 111 (16) 5872-5877; first published April 7, 2014. https://doi.org/10.1073/pnas.1402259111
Biophysics and Computational Biology
- You have accessSubstrate-induced changes in the structural properties of LacYTetiana Serdiuk, M. Gregor Madej, Junichi Sugihara, Shiho Kawamura, Stefania A. Mari, H. Ronald Kaback, and Daniel J. MüllerPNAS April 22, 2014 111 (16) E1571-E1580; first published April 7, 2014. https://doi.org/10.1073/pnas.1404446111
- Open AccessBending forces plastically deform growing bacterial cell wallsAriel Amir, Farinaz Babaeipour, Dustin B. McIntosh, David R. Nelson, and Suckjoon JunPNAS April 22, 2014 111 (16) 5778-5783; first published April 7, 2014. https://doi.org/10.1073/pnas.1317497111
- You have accessOuter membrane β-barrel protein folding is physically controlled by periplasmic lipid head groups and BamADennis Gessmann, Yong Hee Chung, Emily J. Danoff, Ashlee M. Plummer, Clifford W. Sandlin, Nathan R. Zaccai, and Karen G. FlemingPNAS April 22, 2014 111 (16) 5878-5883; first published April 8, 2014. https://doi.org/10.1073/pnas.1322473111
Cell Biology
- You have accessIntegrative framework for identification of key cell identity genes uncovers determinants of ES cell identity and homeostasisSenthilkumar Cinghu, Sailu Yellaboina, Johannes M. Freudenberg, Swati Ghosh, Xiaofeng Zheng, Andrew J. Oldfield, Brad L. Lackford, Dmitri V. Zaykin, Guang Hu, and Raja JothiPNAS April 22, 2014 111 (16) E1581-E1590; first published April 7, 2014. https://doi.org/10.1073/pnas.1318598111
- You have accessMpl expression on megakaryocytes and platelets is dispensable for thrombopoiesis but essential to prevent myeloproliferationAshley P. Ng, Maria Kauppi, Donald Metcalf, Craig D. Hyland, Emma C. Josefsson, Marion Lebois, Jian-Guo Zhang, Tracey M. Baldwin, Ladina Di Rago, Douglas J. Hilton, and Warren S. AlexanderPNAS April 22, 2014 111 (16) 5884-5889; first published April 7, 2014. https://doi.org/10.1073/pnas.1404354111
- You have accessCG hypomethylation in Lsh−/− mouse embryonic fibroblasts is associated with de novo H3K4me1 formation and altered cellular plasticityWeishi Yu, Victorino Briones, Ryan Lister, Carl McIntosh, Yixing Han, Eunice Y. Lee, Jianke Ren, Minoru Terashima, Robert M. Leighty, Joseph R. Ecker, and Kathrin MueggePNAS April 22, 2014 111 (16) 5890-5895; first published April 7, 2014. https://doi.org/10.1073/pnas.1320945111
- You have accessSynthetic control of mammalian-cell motility by engineering chemotaxis to an orthogonal bioinert chemical signalJason S. Park, Benjamin Rhau, Aynur Hermann, Krista A. McNally, Carmen Zhou, Delquin Gong, Orion D. Weiner, Bruce R. Conklin, James Onuffer, and Wendell A. LimPNAS April 22, 2014 111 (16) 5896-5901; first published April 7, 2014. https://doi.org/10.1073/pnas.1402087111
- You have accessErbin is a negative modulator of cardiac hypertrophyInbal Rachmin, Sagi Tshori, Yoav Smith, Amit Oppenheim, Sylvie Marchetto, Gillian Kay, Roger S.-Y. Foo, Noa Dagan, Eliahu Golomb, Dan Gilon, Jean-Paul Borg, and Ehud RazinPNAS April 22, 2014 111 (16) 5902-5907; first published April 7, 2014. https://doi.org/10.1073/pnas.1320350111
- Open AccessBiologically-active laminin-111 fragment that modulates the epithelial-to-mesenchymal transition in embryonic stem cellsChristine-Maria Horejs, Andrea Serio, Alan Purvis, Adam J. Gormley, Sergio Bertazzo, Anna Poliniewicz, Alex J. Wang, Peter DiMaggio, Erhard Hohenester, and Molly M. StevensPNAS April 22, 2014 111 (16) 5908-5913; first published April 3, 2014. https://doi.org/10.1073/pnas.1403139111
Environmental Sciences
- You have accessChanges in peat chemistry associated with permafrost thaw increase greenhouse gas productionSuzanne B. Hodgkins, Malak M. Tfaily, Carmody K. McCalley, Tyler A. Logan, Patrick M. Crill, Scott R. Saleska, Virginia I. Rich, and Jeffrey P. ChantonPNAS April 22, 2014 111 (16) 5819-5824; first published April 7, 2014. https://doi.org/10.1073/pnas.1314641111
Evolution
- You have accessLong-term morphological stasis maintained by a plant–pollinator mutualismCharles C. Davis, Hanno Schaefer, Zhenxiang Xi, David A. Baum, Michael J. Donoghue, and Luke J. HarmonPNAS April 22, 2014 111 (16) 5914-5919; first published April 4, 2014. https://doi.org/10.1073/pnas.1403157111
- You have accessEvolutionary diversity and taxon-specific modifications of the RNA polymerase II C-terminal domainChunlin Yang and John W. StillerPNAS April 22, 2014 111 (16) 5920-5925; first published April 7, 2014. https://doi.org/10.1073/pnas.1323616111
- You have accessMassive programmed translational jumping in mitochondriaB. Franz Lang, Michaela Jakubkova, Eva Hegedusova, Rachid Daoud, Lise Forget, Brona Brejova, Tomas Vinar, Peter Kosa, Dominika Fricova, Martina Nebohacova, Peter Griac, Lubomir Tomaska, Gertraud Burger, and Jozef NosekPNAS April 22, 2014 111 (16) 5926-5931; first published April 7, 2014. https://doi.org/10.1073/pnas.1322190111
- You have accessDNA methylation and evolution of duplicate genesThomas E. Keller and Soojin V. YiPNAS April 22, 2014 111 (16) 5932-5937; first published April 7, 2014. https://doi.org/10.1073/pnas.1321420111
- Open AccessHost adaptation to viruses relies on few genes with different cross-resistance propertiesNelson E. Martins, Vítor G. Faria, Viola Nolte, Christian Schlötterer, Luis Teixeira, Élio Sucena, and Sara MagalhãesPNAS April 22, 2014 111 (16) 5938-5943; first published April 7, 2014. https://doi.org/10.1073/pnas.1400378111
Genetics
- Open AccessSocial disadvantage, genetic sensitivity, and children’s telomere lengthColter Mitchell, John Hobcraft, Sara S. McLanahan, Susan Rutherford Siegel, Arthur Berg, Jeanne Brooks-Gunn, Irwin Garfinkel, and Daniel NottermanPNAS April 22, 2014 111 (16) 5944-5949; first published April 7, 2014. https://doi.org/10.1073/pnas.1404293111
See companion article:
- Reply to Drury and Theall: No stratification- Jun 02, 2014
- You have accessSUMOylation regulates telomere length by targeting the shelterin subunit Tpz1Tpp1 to modulate shelterin–Stn1 interaction in fission yeastKeisuke Miyagawa, Ross S. Low, Venny Santosa, Hiroki Tsuji, Bettina A. Moser, Shiho Fujisawa, Jennifer L. Harland, Olga N. Raguimova, Andrew Go, Masaru Ueno, Akihisa Matsuyama, Minoru Yoshida, Toru M. Nakamura, and Katsunori TanakaPNAS April 22, 2014 111 (16) 5950-5955; first published April 7, 2014. https://doi.org/10.1073/pnas.1401359111
- You have accessThe Caenorhabditis elegans HP1 family protein HPL-2 maintains ER homeostasis through the UPR and hormesisLucie Kozlowski, Steve Garvis, Cécile Bedet, and Francesca PalladinoPNAS April 22, 2014 111 (16) 5956-5961; first published April 8, 2014. https://doi.org/10.1073/pnas.1321698111
- You have accessHst3 is turned over by a replication stress-responsive SCFCdc4 phospho-degronEllen R. Edenberg, Ajay A. Vashisht, Benjamin R. Topacio, James A. Wohlschlegel, and David P. ToczyskiPNAS April 22, 2014 111 (16) 5962-5967; first published April 8, 2014. https://doi.org/10.1073/pnas.1315325111
- Open AccessGenetic variation associated with euphorigenic effects of d-amphetamine is associated with diminished risk for schizophrenia and attention deficit hyperactivity disorderAmy B. Hart, Eric R. Gamazon, Barbara E. Engelhardt, Pamela Sklar, Anna K. Kähler, Christina M. Hultman, Patrick F. Sullivan, Benjamin M. Neale, Stephen V. Faraone, Psychiatric Genomics Consortium: ADHD Subgroup, Harriet de Wit, Nancy J. Cox, and Abraham A. PalmerPNAS April 22, 2014 111 (16) 5968-5973; first published April 7, 2014. https://doi.org/10.1073/pnas.1318810111
Immunology
- You have accessThe nature and extent of contributions by defective ribosome products to the HLA peptidomeDmitry Bourdetsky, Christian E. H. Schmelzer, and Arie AdmonPNAS April 22, 2014 111 (16) E1591-E1599; first published April 8, 2014. https://doi.org/10.1073/pnas.1321902111
- You have accessGranzyme K synergistically potentiates LPS-induced cytokine responses in human monocytesAnnette C. Wensink, Vera Kemp, Job Fermie, M. Isabel García Laorden, Tom van der Poll, C. Erik Hack, and Niels BovenschenPNAS April 22, 2014 111 (16) 5974-5979; first published April 7, 2014. https://doi.org/10.1073/pnas.1317347111
- You have accessDistinctive properties of identical twins' TCR repertoires revealed by high-throughput sequencing
- From the Cover
Ivan V. Zvyagin, Mikhail V. Pogorelyy, Marina E. Ivanova, Ekaterina A. Komech, Mikhail Shugay, Dmitry A. Bolotin, Andrey A. Shelenkov, Alexey A. Kurnosov, Dmitriy B. Staroverov, Dmitriy M. Chudakov, Yuri B. Lebedev, and Ilgar Z. MamedovPNAS April 22, 2014 111 (16) 5980-5985; first published April 7, 2014. https://doi.org/10.1073/pnas.1319389111 - You have accessDifferentiation of CD11c+CX3CR1+ cells in the small intestine requires Notch signalingChieko Ishifune, Satoshi Maruyama, Yuki Sasaki, Hideo Yagita, Katsuto Hozumi, Taisuke Tomita, Kenji Kishihara, and Koji YasutomoPNAS April 22, 2014 111 (16) 5986-5991; first published April 7, 2014. https://doi.org/10.1073/pnas.1401671111
- Open AccessGlycan variants of a respiratory syncytial virus antibody with enhanced effector function and in vivo efficacyAndrew Hiatt, Natasha Bohorova, Ognian Bohorov, Charles Goodman, Do Kim, Michael H. Pauly, Jesus Velasco, Kevin J. Whaley, Pedro A. Piedra, Brian E. Gilbert, and Larry ZeitlinPNAS April 22, 2014 111 (16) 5992-5997; first published April 7, 2014. https://doi.org/10.1073/pnas.1402458111
Medical Sciences
- You have accessp53 constrains progression to anaplastic thyroid carcinoma in a Braf-mutant mouse model of papillary thyroid cancerDavid G. McFadden, Amanda Vernon, Philip M. Santiago, Raul Martinez-McFaline, Arjun Bhutkar, Denise M. Crowley, Martin McMahon, Peter M. Sadow, and Tyler JacksPNAS April 22, 2014 111 (16) E1600-E1609; first published April 7, 2014. https://doi.org/10.1073/pnas.1404357111
- You have accessCharacterizing asthma from a drop of blood using neutrophil chemotaxisEric Karl-Heinz Sackmann, Erwin Berthier, Elizabeth A. Schwantes, Paul S. Fichtinger, Michael D. Evans, Laura L. Dziadzio, Anna Huttenlocher, Sameer K. Mathur, and David J. BeebePNAS April 22, 2014 111 (16) 5813-5818; first published April 7, 2014. https://doi.org/10.1073/pnas.1324043111
- You have accessInverse hormesis of cancer growth mediated by narrow ranges of tumor-directed antibodiesOliver M. T. Pearce, Heinz Läubli, Andrea Verhagen, Patrick Secrest, Jiquan Zhang, Nissi M. Varki, Paul R. Crocker, Jack D. Bui, and Ajit VarkiPNAS April 22, 2014 111 (16) 5998-6003; first published April 7, 2014. https://doi.org/10.1073/pnas.1209067111
- You have accessAnnexin A6 modifies muscular dystrophy by mediating sarcolemmal repairKayleigh A. Swaggart, Alexis R. Demonbreun, Andy H. Vo, Kaitlin E. Swanson, Ellis Y. Kim, John P. Fahrenbach, Jenan Holley-Cuthrell, Ascia Eskin, Zugen Chen, Kevin Squire, Ahlke Heydemann, Abraham A. Palmer, Stanley F. Nelson, and Elizabeth M. McNallyPNAS April 22, 2014 111 (16) 6004-6009; first published April 9, 2014. https://doi.org/10.1073/pnas.1324242111
- You have accessAn engineered muscle flap for reconstruction of large soft tissue defectsYulia Shandalov, Dana Egozi, Jacob Koffler, Dekel Dado-Rosenfeld, David Ben-Shimol, Alina Freiman, Erez Shor, Aviva Kabala, and Shulamit LevenbergPNAS April 22, 2014 111 (16) 6010-6015; first published April 7, 2014. https://doi.org/10.1073/pnas.1402679111
Microbiology
- You have accessBile salts act as effective protein-unfolding agents and instigators of disulfide stress in vivoClaudia M. Cremers, Daniela Knoefler, Victor Vitvitsky, Ruma Banerjee, and Ursula JakobPNAS April 22, 2014 111 (16) E1610-E1619; first published April 4, 2014. https://doi.org/10.1073/pnas.1401941111
- You have accessReplication protein of tobacco mosaic virus cotranslationally binds the 5′ untranslated region of genomic RNA to enable viral replicationKazue Kawamura-Nagaya, Kazuhiro Ishibashi, Ying-Ping Huang, Shuhei Miyashita, and Masayuki IshikawaPNAS April 22, 2014 111 (16) E1620-E1628; first published April 7, 2014. https://doi.org/10.1073/pnas.1321660111
- You have accessDegenerate target sites mediate rapid primed CRISPR adaptationPeter C. Fineran, Matthias J. H. Gerritzen, María Suárez-Diez, Tim Künne, Jos Boekhorst, Sacha A. F. T. van Hijum, Raymond H. J. Staals, and Stan J. J. BrounsPNAS April 22, 2014 111 (16) E1629-E1638; first published April 7, 2014. https://doi.org/10.1073/pnas.1400071111
- You have accessImportance of positioning for microbial evolutionWook Kim, Fernando Racimo, Jonas Schluter, Stuart B. Levy, and Kevin R. FosterPNAS April 22, 2014 111 (16) E1639-E1647; first published April 8, 2014. https://doi.org/10.1073/pnas.1323632111
- You have accessStaphylococcal pathogenicity island DNA packaging system involving cos-site packaging and phage-encoded HNH endonucleasesNuria Quiles-Puchalt, Nuria Carpena, Juan C. Alonso, Richard P. Novick, Alberto Marina, and José R. PenadésPNAS April 22, 2014 111 (16) 6016-6021; first published April 7, 2014. https://doi.org/10.1073/pnas.1320538111
See companion article:
- HNH proteins play a role in phage DNA packaging- Apr 07, 2014
- You have accessHNH proteins are a widespread component of phage DNA packaging machinesSmriti Kala, Nichole Cumby, Paul D. Sadowski, Batool Zafar Hyder, Voula Kanelis, Alan R. Davidson, and Karen L. MaxwellPNAS April 22, 2014 111 (16) 6022-6027; first published April 7, 2014. https://doi.org/10.1073/pnas.1320952111
See companion article:
- Cos site-based SaPI DNA packaging- Apr 07, 2014
- You have accessQuinacrine promotes replication and conformational mutation of chronic wasting disease prionsJifeng Bian, Hae-Eun Kang, and Glenn C. TellingPNAS April 22, 2014 111 (16) 6028-6033; first published April 7, 2014. https://doi.org/10.1073/pnas.1322377111
- You have accessFurin cleavage of the Moloney murine leukemia virus Env precursor reorganizes the spike structureMathilda Sjöberg, Shang-Rung Wu, Robin Löving, Kimmo Rantalainen, Birgitta Lindqvist, and Henrik GaroffPNAS April 22, 2014 111 (16) 6034-6039; first published April 7, 2014. https://doi.org/10.1073/pnas.1317972111
- You have accessArthritogenic alphaviral infection perturbs osteoblast function and triggers pathologic bone loss
- From the Cover
Weiqiang Chen, Suan-Sin Foo, Nestor E. Rulli, Adam Taylor, Kuo-Ching Sheng, Lara J. Herrero, Belinda L. Herring, Brett A. Lidbury, Rachel W. Li, Nicole C. Walsh, Natalie A. Sims, Paul N. Smith, and Suresh MahalingamPNAS April 22, 2014 111 (16) 6040-6045; first published April 14, 2014. https://doi.org/10.1073/pnas.1318859111See companion article:
- Mechanisms underlying alphaviral arthritis- Apr 14, 2014
- You have accessGuanylate binding proteins promote caspase-11–dependent pyroptosis in response to cytoplasmic LPSDanielle M. Pilla, Jon A. Hagar, Arun K. Haldar, Ashley K. Mason, Daniel Degrandi, Klaus Pfeffer, Robert K. Ernst, Masahiro Yamamoto, Edward A. Miao, and Jörn CoersPNAS April 22, 2014 111 (16) 6046-6051; first published April 8, 2014. https://doi.org/10.1073/pnas.1321700111
Neuroscience
- You have accessHypocretin (orexin) facilitates reward by attenuating the antireward effects of its cotransmitter dynorphin in ventral tegmental area
- From the Cover
John W. Muschamp, Jonathan A. Hollander, Jennifer L. Thompson, George Voren, Linda C. Hassinger, Sara Onvani, Theodore M. Kamenecka, Stephanie L. Borgland, Paul J. Kenny, and William A. Carlezon Jr.PNAS April 22, 2014 111 (16) E1648-E1655; first published March 24, 2014. https://doi.org/10.1073/pnas.1315542111See companion article:
- Dynorphin versus hypocretin- Mar 27, 2014
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Physiology
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Plant Biology
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Sustainability Science
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Corrections
- You have accessCorrection for Sun et al., Sel1L is indispensable for mammalian endoplasmic reticulum-associated degradation, endoplasmic reticulum homeostasis, and survivalPNAS April 22, 2014 111 (16) 6115; first published April 1, 2014. https://doi.org/10.1073/pnas.1405563111
- You have accessCorrection for Howe et al., Tackling soil diversity with the assembly of large, complex metagenomesPNAS April 22, 2014 111 (16) 6115; first published April 4, 2014. https://doi.org/10.1073/pnas.1405719111
- You have accessCorrection for Seo et al., Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophyPNAS April 22, 2014 111 (16) 6115; first published March 27, 2014. https://doi.org/10.1073/pnas.1405263111
- You have accessCorrection for Messer et al., Dengue virus envelope protein domain I/II hinge determines long-lived serotype-specific dengue immunityPNAS April 22, 2014 111 (16) 6115; first published April 2, 2014. https://doi.org/10.1073/pnas.1405351111
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