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Table of Contents
July 22, 2014; vol. 111 no. 29
This Week in PNAS
Letters (Online Only)
- You have accessAre viral small RNA regulating Dengue virus replication beyond serotype 2?Esteban FinolPNAS July 22, 2014 111 (29) E2915-E2916; first published July 14, 2014. https://doi.org/10.1073/pnas.1409972111
- You have accessReply to Finol: Viral small RNA from Dengue virus and its regulatory role in different serotypesMazhar Hussain and Sassan AsgariPNAS July 22, 2014 111 (29) E2917; first published July 14, 2014. https://doi.org/10.1073/pnas.1410765111
See companion article:
- Dengue virus 2 encodes a functional small RNA- Feb 03, 2014
Science and Culture
How science intersects with culture.
- You have accessScience and Culture: Hunting fractals in the music of J. S. Bach
- Front Matter
Stephen Ornes
QnAs
- You have accessQnAs with Thomas JessellPrashant NairPNAS July 22, 2014 111 (29) 10394-10395; first published June 9, 2014. https://doi.org/10.1073/pnas.1409335111
PNAS Plus Significance Statements
Brief statements written by the authors about the significance of their papers.
Physical Sciences
Applied Mathematics
- You have accessA simple generative model of collective online behaviorJames P. Gleeson, Davide Cellai, Jukka-Pekka Onnela, Mason A. Porter, and Felix Reed-TsochasPNAS July 22, 2014 111 (29) 10411-10415; first published July 7, 2014. https://doi.org/10.1073/pnas.1313895111
- Open AccessThe role of older children and adults in wild poliovirus transmission
- From the Cover
Isobel M. Blake, Rebecca Martin, Ajay Goel, Nino Khetsuriani, Johannes Everts, Christopher Wolff, Steven Wassilak, R. Bruce Aylward, and Nicholas C. GrasslyPNAS July 22, 2014 111 (29) 10604-10609; first published July 7, 2014. https://doi.org/10.1073/pnas.1323688111
Applied Physical Sciences
- You have accessSERS and MD simulation studies of a kinase inhibitor demonstrate the emergence of a potential drug discovery toolDhanasekaran Karthigeyan, Soumik Siddhanta, Annavarapu Hari Kishore, Sathya S. R. R. Perumal, Hans Ågren, Surabhi Sudevan, Akshay V. Bhat, Karanam Balasubramanyam, Rangappa Kanchugarakoppal Subbegowda, Tapas K. Kundu, and Chandrabhas NarayanaPNAS July 22, 2014 111 (29) 10416-10421; first published June 27, 2014. https://doi.org/10.1073/pnas.1402695111
- You have accessRole of projection in the control of bird flocksDaniel J. G. Pearce, Adam M. Miller, George Rowlands, and Matthew S. TurnerPNAS July 22, 2014 111 (29) 10422-10426; first published July 7, 2014. https://doi.org/10.1073/pnas.1402202111
- You have accessCollective spin 1 singlet phase in high-pressure oxygenYanier Crespo, Michele Fabrizio, Sandro Scandolo, and Erio TosattiPNAS July 22, 2014 111 (29) 10427-10432; first published July 7, 2014. https://doi.org/10.1073/pnas.1404590111
- You have accessThe magnetoelectrochemical switchPetru Lunca Popa, Neil T. Kemp, Hicham Majjad, Guillaume Dalmas, Vina Faramarzi, Christian Andreas, Riccardo Hertel, and Bernard DoudinPNAS July 22, 2014 111 (29) 10433-10437; first published July 9, 2014. https://doi.org/10.1073/pnas.1322828111
Chemistry
- Open AccessUnusual kinetics of thermal decay of dim-light photoreceptors in vertebrate visionYing Guo, Sivakumar Sekharan, Jian Liu, Victor S. Batista, John C. Tully, and Elsa C. Y. YanPNAS July 22, 2014 111 (29) 10438-10443; first published July 7, 2014. https://doi.org/10.1073/pnas.1410826111
- You have accessDetouring of cisplatin to access mitochondrial genome for overcoming resistanceSean Marrache, Rakesh K. Pathak, and Shanta DharPNAS July 22, 2014 111 (29) 10444-10449; first published July 7, 2014. https://doi.org/10.1073/pnas.1405244111
- You have accessAlteration of the lipid profile in lymphomas induced by MYC overexpressionLivia S. Eberlin, Meital Gabay, Alice C. Fan, Arvin M. Gouw, Robert J. Tibshirani, Dean W. Felsher, and Richard N. ZarePNAS July 22, 2014 111 (29) 10450-10455; first published July 3, 2014. https://doi.org/10.1073/pnas.1409778111
- You have accessCrystal structure and encapsulation dynamics of ice II-structured neon hydrateXiaohui Yu, Jinlong Zhu, Shiyu Du, Hongwu Xu, Sven C. Vogel, Jiantao Han, Timothy C. Germann, Jianzhong Zhang, Changqing Jin, Joseph S. Francisco, and Yusheng ZhaoPNAS July 22, 2014 111 (29) 10456-10461; first published July 7, 2014. https://doi.org/10.1073/pnas.1410690111
- You have accessTesting for memory-free spectroscopic coordinates by 3D IR exchange spectroscopyJoanna A. Borek, Fivos Perakis, and Peter HammPNAS July 22, 2014 111 (29) 10462-10467; first published July 7, 2014. https://doi.org/10.1073/pnas.1406967111
- Open AccessCovalent agonists for studying G protein-coupled receptor activationDietmar Weichert, Andrew C. Kruse, Aashish Manglik, Christine Hiller, Cheng Zhang, Harald Hübner, Brian K. Kobilka, and Peter GmeinerPNAS July 22, 2014 111 (29) 10744-10748; first published July 8, 2014. https://doi.org/10.1073/pnas.1410415111
Computer Sciences
- Open AccessAlgorithms, games, and evolution
- From the Cover
Erick Chastain, Adi Livnat, Christos Papadimitriou, and Umesh VaziraniPNAS July 22, 2014 111 (29) 10620-10623; first published June 16, 2014. https://doi.org/10.1073/pnas.1406556111See companion article:
- Selection in evolution and computer science- Jul 09, 2014
Earth, Atmospheric, and Planetary Sciences
- Open AccessSpin crossover in ferropericlase and velocity heterogeneities in the lower mantleZhongqing Wu and Renata M. WentzcovitchPNAS July 22, 2014 111 (29) 10468-10472; first published July 7, 2014. https://doi.org/10.1073/pnas.1322427111
- You have accessStone tools from the ancient Tongan state reveal prehistoric interaction centers in the Central PacificGeoffrey R. Clark, Christian Reepmeyer, Nivaleti Melekiola, Jon Woodhead, William R. Dickinson, and Helene Martinsson-WallinPNAS July 22, 2014 111 (29) 10491-10496; first published July 7, 2014. https://doi.org/10.1073/pnas.1406165111
- You have accessFlight performance of the largest volant birdDaniel T. KsepkaPNAS July 22, 2014 111 (29) 10624-10629; first published July 7, 2014. https://doi.org/10.1073/pnas.1320297111
Engineering
- Open AccessDevice design and materials optimization of conformal coating for islets of Langerhans
- From the Cover
Alice A. Tomei, Vita Manzoli, Christopher A. Fraker, Jaime Giraldo, Diana Velluto, Mejdi Najjar, Antonello Pileggi, R. Damaris Molano, Camillo Ricordi, Cherie L. Stabler, and Jeffrey A. HubbellPNAS July 22, 2014 111 (29) 10514-10519; first published June 30, 2014. https://doi.org/10.1073/pnas.1402216111 - Open AccessIntratumor heterogeneity alters most effective drugs in designed combinationsBoyang Zhao, Michael T. Hemann, and Douglas A. LauffenburgerPNAS July 22, 2014 111 (29) 10773-10778; first published July 7, 2014. https://doi.org/10.1073/pnas.1323934111
See companion article:
- Drug combinations for heterogeneous tumors- Sep 24, 2014
Environmental Sciences
- You have accessUnspeciated organic emissions from combustion sources and their influence on the secondary organic aerosol budget in the United StatesShantanu H. Jathar, Timothy D. Gordon, Christopher J. Hennigan, Havala O. T. Pye, George Pouliot, Peter J. Adams, Neil M. Donahue, and Allen L. RobinsonPNAS July 22, 2014 111 (29) 10473-10478; first published July 7, 2014. https://doi.org/10.1073/pnas.1323740111
Physics
- Open Access4D multiple-cathode ultrafast electron microscopyJohn Spencer Baskin, Haihua Liu, and Ahmed H. ZewailPNAS July 22, 2014 111 (29) 10479-10484; first published July 8, 2014. https://doi.org/10.1073/pnas.1411650111
- You have accessGiant vacuum forces via transmission linesEphraim Shahmoon, Igor Mazets, and Gershon KurizkiPNAS July 22, 2014 111 (29) 10485-10490; first published July 7, 2014. https://doi.org/10.1073/pnas.1401346111
Social Sciences
Anthropology
- You have accessStone tools from the ancient Tongan state reveal prehistoric interaction centers in the Central PacificGeoffrey R. Clark, Christian Reepmeyer, Nivaleti Melekiola, Jon Woodhead, William R. Dickinson, and Helene Martinsson-WallinPNAS July 22, 2014 111 (29) 10491-10496; first published July 7, 2014. https://doi.org/10.1073/pnas.1406165111
- You have accessEnvironmental impact of geometric earthwork construction in pre-Columbian AmazoniaJohn Francis Carson, Bronwen S. Whitney, Francis E. Mayle, José Iriarte, Heiko Prümers, J. Daniel Soto, and Jennifer WatlingPNAS July 22, 2014 111 (29) 10497-10502; first published July 7, 2014. https://doi.org/10.1073/pnas.1321770111
See companion article:
- Reply to Silva: South American ecotonal dynamics- Aug 26, 2014
Economic Sciences
- Open AccessIrrational exuberance and neural crash warning signals during endogenous experimental market bubblesAlec Smith, Terry Lohrenz, Justin King, P. Read Montague, and Colin F. CamererPNAS July 22, 2014 111 (29) 10503-10508; first published July 7, 2014. https://doi.org/10.1073/pnas.1318416111
Social Sciences
- You have accessA simple generative model of collective online behaviorJames P. Gleeson, Davide Cellai, Jukka-Pekka Onnela, Mason A. Porter, and Felix Reed-TsochasPNAS July 22, 2014 111 (29) 10411-10415; first published July 7, 2014. https://doi.org/10.1073/pnas.1313895111
Biological Sciences
Anthropology
- You have accessTemporal labyrinths of eastern Eurasian Pleistocene humansXiu-Jie Wu, Isabelle Crevecoeur, Wu Liu, Song Xing, and Erik TrinkausPNAS July 22, 2014 111 (29) 10509-10513; first published July 7, 2014. https://doi.org/10.1073/pnas.1410735111
Applied Biological Sciences
- Open AccessDevice design and materials optimization of conformal coating for islets of Langerhans
- From the Cover
Alice A. Tomei, Vita Manzoli, Christopher A. Fraker, Jaime Giraldo, Diana Velluto, Mejdi Najjar, Antonello Pileggi, R. Damaris Molano, Camillo Ricordi, Cherie L. Stabler, and Jeffrey A. HubbellPNAS July 22, 2014 111 (29) 10514-10519; first published June 30, 2014. https://doi.org/10.1073/pnas.1402216111
Biochemistry
- You have accessPhosphoproteomic analysis identifies the tumor suppressor PDCD4 as a RSK substrate negatively regulated by 14-3-3Jacob A. Galan, Kathryn M. Geraghty, Geneviève Lavoie, Evgeny Kanshin, Joseph Tcherkezian, Viviane Calabrese, Grace R. Jeschke, Benjamin E. Turk, Bryan A. Ballif, John Blenis, Pierre Thibault, and Philippe P. RouxPNAS July 22, 2014 111 (29) E2918-E2927; first published July 7, 2014. https://doi.org/10.1073/pnas.1405601111
- You have accessDEAD-box protein CYT-19 is activated by exposed helices in a group I intron RNAInga Jarmoskaite, Hari Bhaskaran, Soenke Seifert, and Rick RussellPNAS July 22, 2014 111 (29) E2928-E2936; first published July 7, 2014. https://doi.org/10.1073/pnas.1404307111
- You have accessMolecular mechanisms for the regulation of histone mRNA stem-loop–binding protein by phosphorylationJun Zhang, Dazhi Tan, Eugene F. DeRose, Lalith Perera, Zbigniew Dominski, William F. Marzluff, Liang Tong, and Traci M. Tanaka HallPNAS July 22, 2014 111 (29) E2937-E2946; first published July 7, 2014. https://doi.org/10.1073/pnas.1406381111
- You have accessStructure of a new DNA-binding domain which regulates pathogenesis in a wide variety of fungi
- Inaugural Article
Matthew B. Lohse, Oren S. Rosenberg, Jeffery S. Cox, Robert M. Stroud, Janet S. Finer-Moore, and Alexander D. JohnsonPNAS July 22, 2014 111 (29) 10404-10410; first published July 3, 2014. https://doi.org/10.1073/pnas.1410110111See companion article:
- Profile of Alexander D. Johnson- Aug 11, 2014
- You have accessAncient translation factor is essential for tRNA-dependent cysteine biosynthesis in methanogenic archaeaYuchen Liu, Akiyoshi Nakamura, Yuto Nakazawa, Nozomi Asano, Kara A. Ford, Michael J. Hohn, Isao Tanaka, Min Yao, and Dieter SöllPNAS July 22, 2014 111 (29) 10520-10525; first published July 7, 2014. https://doi.org/10.1073/pnas.1411267111
- You have accessCrystal structure of mammalian selenocysteine-dependent iodothyronine deiodinase suggests a peroxiredoxin-like catalytic mechanismUlrich Schweizer, Christine Schlicker, Doreen Braun, Josef Köhrle, and Clemens SteegbornPNAS July 22, 2014 111 (29) 10526-10531; first published July 7, 2014. https://doi.org/10.1073/pnas.1323873111
- You have accessIdentification of a two-component fatty acid kinase responsible for host fatty acid incorporation by Staphylococcus aureusJoshua B. Parsons, Tyler C. Broussard, Jeffrey L. Bose, Jason W. Rosch, Pamela Jackson, Chitra Subramanian, and Charles O. RockPNAS July 22, 2014 111 (29) 10532-10537; first published July 7, 2014. https://doi.org/10.1073/pnas.1408797111
- You have accessThe Legionella effector SidC defines a unique family of ubiquitin ligases important for bacterial phagosomal remodelingFoSheng Hsu, Xi Luo, Jiazhang Qiu, Yan-Bin Teng, Jianping Jin, Marcus B. Smolka, Zhao-Qing Luo, and Yuxin MaoPNAS July 22, 2014 111 (29) 10538-10543; first published July 8, 2014. https://doi.org/10.1073/pnas.1402605111
- You have accessAllosteric regulation of γ-secretase activity by a phenylimidazole-type γ-secretase modulatorKoji Takeo, Shun Tanimura, Takehiro Shinoda, Satoko Osawa, Ivan Krasmirov Zahariev, Naoki Takegami, Yoshiko Ishizuka-Katsura, Naoko Shinya, Shizuka Takagi-Niidome, Aya Tominaga, Noboru Ohsawa, Tomomi Kimura-Someya, Mikako Shirouzu, Satoshi Yokoshima, Shigeyuki Yokoyama, Tohru Fukuyama, Taisuke Tomita, and Takeshi IwatsuboPNAS July 22, 2014 111 (29) 10544-10549; first published July 9, 2014. https://doi.org/10.1073/pnas.1402171111
Biophysics and Computational Biology
- You have accessCatalytic strategy used by the myosin motor to hydrolyze ATPFarooq Ahmad Kiani and Stefan FischerPNAS July 22, 2014 111 (29) E2947-E2956; first published July 8, 2014. https://doi.org/10.1073/pnas.1401862111
- You have accessSERS and MD simulation studies of a kinase inhibitor demonstrate the emergence of a potential drug discovery toolDhanasekaran Karthigeyan, Soumik Siddhanta, Annavarapu Hari Kishore, Sathya S. R. R. Perumal, Hans Ågren, Surabhi Sudevan, Akshay V. Bhat, Karanam Balasubramanyam, Rangappa Kanchugarakoppal Subbegowda, Tapas K. Kundu, and Chandrabhas NarayanaPNAS July 22, 2014 111 (29) 10416-10421; first published June 27, 2014. https://doi.org/10.1073/pnas.1402695111
- Open AccessUnusual kinetics of thermal decay of dim-light photoreceptors in vertebrate visionYing Guo, Sivakumar Sekharan, Jian Liu, Victor S. Batista, John C. Tully, and Elsa C. Y. YanPNAS July 22, 2014 111 (29) 10438-10443; first published July 7, 2014. https://doi.org/10.1073/pnas.1410826111
- Open AccessEnergy landscape views for interplays among folding, binding, and allostery of calmodulin domainsWenfei Li, Wei Wang, and Shoji TakadaPNAS July 22, 2014 111 (29) 10550-10555; first published July 7, 2014. https://doi.org/10.1073/pnas.1402768111
- Open AccessSimple chained guide trees give high-quality protein multiple sequence alignmentsKieran Boyce, Fabian Sievers, and Desmond G. HigginsPNAS July 22, 2014 111 (29) 10556-10561; first published July 7, 2014. https://doi.org/10.1073/pnas.1405628111
See companion article:
- Real and simulated proteins in MSAs- Jan 06, 2015
- You have accessModulation of frustration in folding by sequence permutationR. Paul Nobrega, Karunesh Arora, Sagar V. Kathuria, Rita Graceffa, Raul A. Barrea, Liang Guo, Srinivas Chakravarthy, Osman Bilsel, Thomas C. Irving, Charles L. Brooks III, and C. Robert MatthewsPNAS July 22, 2014 111 (29) 10562-10567; first published July 7, 2014. https://doi.org/10.1073/pnas.1324230111
Cell Biology
- You have accessRas transformation uncouples the kinesin-coordinated cellular nutrient responseElma Zaganjor, Lauren M. Weil, Joshua X. Gonzales, John D. Minna, and Melanie H. CobbPNAS July 22, 2014 111 (29) 10568-10573; first published July 7, 2014. https://doi.org/10.1073/pnas.1411016111
- You have accessMetformin and phenformin deplete tricarboxylic acid cycle and glycolytic intermediates during cell transformation and NTPs in cancer stem cellsAndreas Janzer, Natalie J. German, Karina N. Gonzalez-Herrera, John M. Asara, Marcia C. Haigis, and Kevin StruhlPNAS July 22, 2014 111 (29) 10574-10579; first published July 7, 2014. https://doi.org/10.1073/pnas.1409844111
- Open AccessAn uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore
- From the Cover
Kambiz N. Alavian, Gisela Beutner, Emma Lazrove, Silvio Sacchetti, Han-A Park, Pawel Licznerski, Hongmei Li, Panah Nabili, Kathryn Hockensmith, Morven Graham, George A. Porter Jr., and Elizabeth A. JonasPNAS July 22, 2014 111 (29) 10580-10585; first published June 16, 2014. https://doi.org/10.1073/pnas.1401591111See companion article:
- Mitochondrial pore rediscovered- Jul 07, 2014
- You have accessTOR complex 2-Ypk1 signaling is an essential positive regulator of the general amino acid control response and autophagyAriadne Vlahakis, Martin Graef, Jodi Nunnari, and Ted PowersPNAS July 22, 2014 111 (29) 10586-10591; first published July 7, 2014. https://doi.org/10.1073/pnas.1406305111
- You have accessTif1γ regulates the TGF-β1 receptor and promotes physiological aging of hematopoietic stem cellsRonan Quéré, Laetitia Saint-Paul, Virginie Carmignac, Romain Z. Martin, Marie-Lorraine Chrétien, Anne Largeot, Arlette Hammann, Jean-Paul Pais de Barros, Jean-Noël Bastie, and Laurent DelvaPNAS July 22, 2014 111 (29) 10592-10597; first published July 7, 2014. https://doi.org/10.1073/pnas.1405546111
Developmental Biology
- Open AccessDynamic regulation of eve stripe 2 expression reveals transcriptional bursts in living Drosophila embryosJacques P. Bothma, Hernan G. Garcia, Emilia Esposito, Gavin Schlissel, Thomas Gregor, and Michael LevinePNAS July 22, 2014 111 (29) 10598-10603; first published July 3, 2014. https://doi.org/10.1073/pnas.1410022111
Ecology
- You have accessRole of projection in the control of bird flocksDaniel J. G. Pearce, Adam M. Miller, George Rowlands, and Matthew S. TurnerPNAS July 22, 2014 111 (29) 10422-10426; first published July 7, 2014. https://doi.org/10.1073/pnas.1402202111
- You have accessEnvironmental impact of geometric earthwork construction in pre-Columbian AmazoniaJohn Francis Carson, Bronwen S. Whitney, Francis E. Mayle, José Iriarte, Heiko Prümers, J. Daniel Soto, and Jennifer WatlingPNAS July 22, 2014 111 (29) 10497-10502; first published July 7, 2014. https://doi.org/10.1073/pnas.1321770111
See companion article:
- Reply to Silva: South American ecotonal dynamics- Aug 26, 2014
- Open AccessThe role of older children and adults in wild poliovirus transmission
- From the Cover
Isobel M. Blake, Rebecca Martin, Ajay Goel, Nino Khetsuriani, Johannes Everts, Christopher Wolff, Steven Wassilak, R. Bruce Aylward, and Nicholas C. GrasslyPNAS July 22, 2014 111 (29) 10604-10609; first published July 7, 2014. https://doi.org/10.1073/pnas.1323688111 - You have accessInvasive plants have broader physiological nichesSteven I. Higgins and David M. RichardsonPNAS July 22, 2014 111 (29) 10610-10614; first published July 2, 2014. https://doi.org/10.1073/pnas.1406075111
Environmental Sciences
- You have accessHerbarium specimens show contrasting phenological responses to Himalayan climateRobbie Hart, Jan Salick, Sailesh Ranjitkar, and Jianchu XuPNAS July 22, 2014 111 (29) 10615-10619; first published July 7, 2014. https://doi.org/10.1073/pnas.1403376111
Evolution
- Open AccessThe fossilized birth–death process for coherent calibration of divergence-time estimatesTracy A. Heath, John P. Huelsenbeck, and Tanja StadlerPNAS July 22, 2014 111 (29) E2957-E2966; first published July 9, 2014. https://doi.org/10.1073/pnas.1319091111
- Open AccessAlgorithms, games, and evolution
- From the Cover
Erick Chastain, Adi Livnat, Christos Papadimitriou, and Umesh VaziraniPNAS July 22, 2014 111 (29) 10620-10623; first published June 16, 2014. https://doi.org/10.1073/pnas.1406556111See companion article:
- Selection in evolution and computer science- Jul 09, 2014
- You have accessFlight performance of the largest volant birdDaniel T. KsepkaPNAS July 22, 2014 111 (29) 10624-10629; first published July 7, 2014. https://doi.org/10.1073/pnas.1320297111
- You have accessDivergence of Drosophila melanogaster repeatomes in response to a sharp microclimate contrast in Evolution Canyon, IsraelYoung Bun Kim, Jung Hun Oh, Lauren J. McIver, Eugenia Rashkovetsky, Katarzyna Michalak, Harold R. Garner, Lin Kang, Eviatar Nevo, Abraham B. Korol, and Pawel MichalakPNAS July 22, 2014 111 (29) 10630-10635; first published July 8, 2014. https://doi.org/10.1073/pnas.1410372111
- You have accessDrastic population fluctuations explain the rapid extinction of the passenger pigeon
- From the Cover
Chih-Ming Hung, Pei-Jen L. Shaner, Robert M. Zink, Wei-Chung Liu, Te-Chin Chu, Wen-San Huang, and Shou-Hsien LiPNAS July 22, 2014 111 (29) 10636-10641; first published June 16, 2014. https://doi.org/10.1073/pnas.1401526111See companion article:
- Range and population in an extinct bird- Jun 30, 2014
Genetics
- Open AccessOptimized CRISPR/Cas tools for efficient germline and somatic genome engineering in DrosophilaFillip Port, Hui-Min Chen, Tzumin Lee, and Simon L. BullockPNAS July 22, 2014 111 (29) E2967-E2976; first published July 7, 2014. https://doi.org/10.1073/pnas.1405500111
- Open AccessMutation of a major CG methylase in rice causes genome-wide hypomethylation, dysregulated genome expression, and seedling lethalityLanjuan Hu, Ning Li, Chunming Xu, Silin Zhong, Xiuyun Lin, Jingjing Yang, Tianqi Zhou, Anzhi Yuliang, Ying Wu, Yun-Ru Chen, Xiaofeng Cao, Assaf Zemach, Sachin Rustgi, Diter von Wettstein, and Bao LiuPNAS July 22, 2014 111 (29) 10642-10647; first published July 7, 2014. https://doi.org/10.1073/pnas.1410761111
- You have accessFGF5 is a crucial regulator of hair length in humansClaire A. Higgins, Lynn Petukhova, Sivan Harel, Yuan Y. Ho, Esther Drill, Lawrence Shapiro, Muhammad Wajid, and Angela M. ChristianoPNAS July 22, 2014 111 (29) 10648-10653; first published July 2, 2014. https://doi.org/10.1073/pnas.1402862111
- You have accessExtensive pathogenicity of mitochondrial heteroplasmy in healthy human individualsKaixiong Ye, Jian Lu, Fei Ma, Alon Keinan, and Zhenglong GuPNAS July 22, 2014 111 (29) 10654-10659; first published July 7, 2014. https://doi.org/10.1073/pnas.1403521111
See companion article:
- MPS and mitochondrial heteroplasmy- Oct 15, 2014
Immunology and Inflammation
- You have accessAdaptive immunity to murine skin commensalsWei Shen, Wenqing Li, Julie A. Hixon, Nicolas Bouladoux, Yasmine Belkaid, Amiran Dzutzev, and Scott K. DurumPNAS July 22, 2014 111 (29) E2977-E2986; first published July 7, 2014. https://doi.org/10.1073/pnas.1401820111
- You have accessBioengineering T cells to target carbohydrate to treat opportunistic fungal infectionPappanaicken R. Kumaresan, Pallavi R. Manuri, Nathaniel D. Albert, Sourindra Maiti, Harjeet Singh, Tiejuan Mi, Jason Roszik, Brian Rabinovich, Simon Olivares, Janani Krishnamurthy, Ling Zhang, Amer M. Najjar, M. Helen Huls, Dean A. Lee, Richard E. Champlin, Dimitrios P. Kontoyiannis, and Laurence J. N. CooperPNAS July 22, 2014 111 (29) 10660-10665; first published July 7, 2014. https://doi.org/10.1073/pnas.1312789111
- You have access25-Hydroxycholesterol acts as an amplifier of inflammatory signalingElizabeth S. Gold, Alan H. Diercks, Irina Podolsky, Rebecca L. Podyminogin, Peter S. Askovich, Piper M. Treuting, and Alan AderemPNAS July 22, 2014 111 (29) 10666-10671; first published July 3, 2014. https://doi.org/10.1073/pnas.1404271111
- You have accessCommensal microbes drive intestinal inflammation by IL-17–producing CD4+ T cells through ICOSL and OX40L costimulation in the absence of B7-1 and B7-2Lijun Xin, Tony T. Jiang, Vandana Chaturvedi, Jeremy M. Kinder, James M. Ertelt, Jared H. Rowe, Kris A. Steinbrecher, and Sing Sing WayPNAS July 22, 2014 111 (29) 10672-10677; first published July 7, 2014. https://doi.org/10.1073/pnas.1402336111
Medical Sciences
- You have accessDetouring of cisplatin to access mitochondrial genome for overcoming resistanceSean Marrache, Rakesh K. Pathak, and Shanta DharPNAS July 22, 2014 111 (29) 10444-10449; first published July 7, 2014. https://doi.org/10.1073/pnas.1405244111
- Open AccessEfficient germ-line transmission obtained with transgene-free induced pluripotent stem cellsSen Wu, Yuanyuan Wu, Xi Zhang, and Mario R. CapecchiPNAS July 22, 2014 111 (29) 10678-10683; first published July 7, 2014. https://doi.org/10.1073/pnas.1409933111
- You have accessTumor suppressor p53 cooperates with SIRT6 to regulate gluconeogenesis by promoting FoxO1 nuclear exclusionPing Zhang, Bo Tu, Hua Wang, Ziyang Cao, Ming Tang, Chaohua Zhang, Bo Gu, Zhiming Li, Lina Wang, Yang Yang, Ying Zhao, Haiying Wang, Jianyuan Luo, Chu-Xia Deng, Bin Gao, Robert G. Roeder, and Wei-Guo ZhuPNAS July 22, 2014 111 (29) 10684-10689; first published July 9, 2014. https://doi.org/10.1073/pnas.1411026111
See companion article:
- Focus on PCK- Sep 26, 2014
- Open AccessDiscrete conformations of epitope II on the hepatitis C virus E2 protein for antibody-mediated neutralization and nonneutralizationLu Deng, Li Ma, Maria Luisa Virata-Theimer, Lilin Zhong, Hailing Yan, Zhong Zhao, Evi Struble, Stephen Feinstone, Harvey Alter, and Pei ZhangPNAS July 22, 2014 111 (29) 10690-10695; first published July 7, 2014. https://doi.org/10.1073/pnas.1411317111
- You have accessG-CSF Induces Membrane Expression of a Myeloperoxidase Glycovariant that Operates as an E-selectin Ligand on Human Myeloid CellsCristina I. Silvescu and Robert SacksteinPNAS July 22, 2014 111 (29) 10696-10701; first published July 7, 2014. https://doi.org/10.1073/pnas.1320833111
Microbiology
- You have accessRhizobial homologs of the fatty acid transporter FadL facilitate perception of long-chain acyl-homoserine lactone signalsElizaveta Krol and Anke BeckerPNAS July 22, 2014 111 (29) 10702-10707; first published July 7, 2014. https://doi.org/10.1073/pnas.1404929111
- You have accessEnhancement of protein expression by alphavirus replicons by designing self-replicating subgenomic RNAsDal Young Kim, Svetlana Atasheva, Alexander J. McAuley, Jessica A. Plante, Elena I. Frolova, David W. C. Beasley, and Ilya FrolovPNAS July 22, 2014 111 (29) 10708-10713; first published July 7, 2014. https://doi.org/10.1073/pnas.1408677111
- Open AccessModeling ecological drivers in marine viral communities using comparative metagenomics and network analysesBonnie L. Hurwitz, Anton H. Westveld, Jennifer R. Brum, and Matthew B. SullivanPNAS July 22, 2014 111 (29) 10714-10719; first published July 7, 2014. https://doi.org/10.1073/pnas.1319778111
Neuroscience
- You have accessAstrocyte activation is suppressed in both normal and injured brain by FGF signalingWenfei Kang, Francesca Balordi, Nan Su, Lin Chen, Gordon Fishell, and Jean M. HébertPNAS July 22, 2014 111 (29) E2987-E2995; first published July 7, 2014. https://doi.org/10.1073/pnas.1320401111
- Open AccessGenetic evidence that Celsr3 and Celsr2, together with Fzd3, regulate forebrain wiring in a Vangl-independent mannerYibo Qu, Yuhua Huang, Jia Feng, Gonzalo Alvarez-Bolado, Elizabeth A. Grove, Yingzi Yang, Fadel Tissir, Libing Zhou, and Andre M. GoffinetPNAS July 22, 2014 111 (29) E2996-E3004; first published July 7, 2014. https://doi.org/10.1073/pnas.1402105111
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- Frizzled3 in axon growth and guidance- May 05, 2014
- You have accessFrizzled3 is required for the development of multiple axon tracts in the mouse central nervous systemZhong L. Hua, Sangmin Jeon, Michael J. Caterina, and Jeremy NathansPNAS July 22, 2014 111 (29) E3005-E3014; first published May 5, 2014. https://doi.org/10.1073/pnas.1406399111
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- Celsr and forebrain wiring- Jul 07, 2014
- Open AccessIrrational exuberance and neural crash warning signals during endogenous experimental market bubblesAlec Smith, Terry Lohrenz, Justin King, P. Read Montague, and Colin F. CamererPNAS July 22, 2014 111 (29) 10503-10508; first published July 7, 2014. https://doi.org/10.1073/pnas.1318416111
- Open AccessCA3 size predicts the precision of memory recallMartin J. Chadwick, Heidi M. Bonnici, and Eleanor A. MaguirePNAS July 22, 2014 111 (29) 10720-10725; first published July 7, 2014. https://doi.org/10.1073/pnas.1319641111
- You have accessThe transcription factor Fezf2 directs the differentiation of neural stem cells in the subventricular zone toward a cortical phenotypeAnnalisa Zuccotti, Corentin Le Magueresse, Min Chen, Angela Neitz, and Hannah MonyerPNAS July 22, 2014 111 (29) 10726-10731; first published July 7, 2014. https://doi.org/10.1073/pnas.1320290111
- You have accessIntramuscular injection of α-synuclein induces CNS α-synuclein pathology and a rapid-onset motor phenotype in transgenic miceAmanda N. Sacino, Mieu Brooks, Michael A. Thomas, Alex B. McKinney, Sooyeon Lee, Robert W. Regenhardt, Nicholas H. McGarvey, Jacob I. Ayers, Lucia Notterpek, David R. Borchelt, Todd E. Golde, and Benoit I. GiassonPNAS July 22, 2014 111 (29) 10732-10737; first published July 7, 2014. https://doi.org/10.1073/pnas.1321785111
- You have accessNeural correlates of auditory streaming in an objective behavioral taskNaoya Itatani and Georg M. KlumpPNAS July 22, 2014 111 (29) 10738-10743; first published July 7, 2014. https://doi.org/10.1073/pnas.1321487111
Pharmacology
- Open AccessCovalent agonists for studying G protein-coupled receptor activationDietmar Weichert, Andrew C. Kruse, Aashish Manglik, Christine Hiller, Cheng Zhang, Harald Hübner, Brian K. Kobilka, and Peter GmeinerPNAS July 22, 2014 111 (29) 10744-10748; first published July 8, 2014. https://doi.org/10.1073/pnas.1410415111
- You have accessStructural basis for cooperative interactions of substituted 2-aminopyrimidines with the acetylcholine binding proteinKatarzyna Kaczanowska, Michal Harel, Zoran Radić, Jean-Pierre Changeux, M. G. Finn, and Palmer TaylorPNAS July 22, 2014 111 (29) 10749-10754; first published July 8, 2014. https://doi.org/10.1073/pnas.1410992111
- You have accessMechanisms underlying the activation of G-protein–gated inwardly rectifying K+ (GIRK) channels by the novel anxiolytic drug, ML297Nicole Wydeven, Ezequiel Marron Fernandez de Velasco, Yu Du, Michael A. Benneyworth, Matthew C. Hearing, Rachel A. Fischer, Mark John Thomas, C. David Weaver, and Kevin WickmanPNAS July 22, 2014 111 (29) 10755-10760; first published July 7, 2014. https://doi.org/10.1073/pnas.1405190111
Physiology
- Open AccessEffect of sleep deprivation on the human metabolomeSarah K. Davies, Joo Ern Ang, Victoria L. Revell, Ben Holmes, Anuska Mann, Francesca P. Robertson, Nanyi Cui, Benita Middleton, Katrin Ackermann, Manfred Kayser, Alfred E. Thumser, Florence I. Raynaud, and Debra J. SkenePNAS July 22, 2014 111 (29) 10761-10766; first published July 7, 2014. https://doi.org/10.1073/pnas.1402663111
Plant Biology
- You have accessAuxin inhibits stomatal development through MONOPTEROS repression of a mobile peptide gene STOMAGEN in mesophyllJing-Yi Zhang, Sheng-Bo He, Ling Li, and Hong-Quan YangPNAS July 22, 2014 111 (29) E3015-E3023; first published July 7, 2014. https://doi.org/10.1073/pnas.1400542111
Population Biology
- Open AccessContact between bird species of different lifespans can promote the emergence of highly pathogenic avian influenza strainsPaul S. Wikramaratna, Oliver G. Pybus, and Sunetra GuptaPNAS July 22, 2014 111 (29) 10767-10772; first published June 23, 2014. https://doi.org/10.1073/pnas.1401849111
Systems Biology
- Open AccessIntratumor heterogeneity alters most effective drugs in designed combinationsBoyang Zhao, Michael T. Hemann, and Douglas A. LauffenburgerPNAS July 22, 2014 111 (29) 10773-10778; first published July 7, 2014. https://doi.org/10.1073/pnas.1323934111
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Corrections
- You have accessEditorial Expression of Concern: Experimental evidence of massivescale emotional contagion through social networksPNAS July 22, 2014 111 (29) 10779; first published July 3, 2014. https://doi.org/10.1073/pnas.1412469111
- You have accessCorrection for Kramer et al., Experimental evidence of massive-scale emotional contagion through social networksPNAS July 22, 2014 111 (29) 10779; first published July 3, 2014. https://doi.org/10.1073/pnas.1412583111
Commentaries
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