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Table of Contents

August 26, 2014; vol. 111 no. 34

This Week in PNAS

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    In This Issue
    PNAS August 26, 2014 111 (34) 12271-12272; https://doi.org/10.1073/iti3414111

Letters (Online Only)

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    Female hurricanes are not deadlier than male hurricanes
    Daniel Malter
    PNAS August 26, 2014 111 (34) E3496; first published August 4, 2014. https://doi.org/10.1073/pnas.1411428111

    See companion article:

    • Are female hurricanes really deadlier?
      - Aug 04, 2014
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    Are female hurricanes really deadlier than male hurricanes?
    Björn Christensen and Sören Christensen
    PNAS August 26, 2014 111 (34) E3497-E3498; first published August 4, 2014. https://doi.org/10.1073/pnas.1410910111

    See companion article:

    • Female hurricane = male hurricane
      - Aug 04, 2014
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    Reply to Christensen and Christensen and to Malter: Pitfalls of erroneous analyses of hurricanes names
    Kiju Jung, Sharon Shavitt, Madhu Viswanathan, and Joseph M. Hilbe
    PNAS August 26, 2014 111 (34) E3499-E3500; first published August 4, 2014. https://doi.org/10.1073/pnas.1411652111

    See companion article:

    • Female hurricanes are deadlier
      - Jun 02, 2014

Inner Workings

An over-the-shoulder look at scientists at work.
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    Inner Workings: 1885, the first rabies vaccination in humans
    • Front Matter
    Rino Rappuoli
    PNAS August 26, 2014 111 (34) 12273; https://doi.org/10.1073/pnas.1414226111

Commentaries

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    Pharmacological chaperones in the age of proteomic pathology
    Scott A. Small
    PNAS August 26, 2014 111 (34) 12274-12275; first published August 13, 2014. https://doi.org/10.1073/pnas.1413111111

    See companion article:

    • A diverse pharmacological chaperone library
      - Jul 14, 2014
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    Clovis at the end of the world
    David J. Meltzer
    PNAS August 26, 2014 111 (34) 12276-12277; first published August 13, 2014. https://doi.org/10.1073/pnas.1412945111

    See companion article:

    • Clovis–gomphothere site in Sonora, Mexico
      - Jul 14, 2014
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    Fungal polyketide engineering comes of age
    Vinayak Agarwal and Bradley S. Moore
    PNAS August 26, 2014 111 (34) 12278-12279; first published August 12, 2014. https://doi.org/10.1073/pnas.1412946111

    See companion article:

    • Combinatorial biosynthesis of fungal polyketides
      - Jul 21, 2014

PNAS Plus Significance Statements

Brief statements written by the authors about the significance of their papers.
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    PNAS Plus Significance Statements
    PNAS August 26, 2014 111 (34) 12280-12281; https://doi.org/10.1073/pnas.ss11134

Vaccines PNAS 100th Anniversary Special Feature (Free Online)

  • Introduction

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      Vaccines: Science, health, longevity, and wealth
      • From the Cover
      Rino Rappuoli
      PNAS August 26, 2014 111 (34) 12282; first published August 19, 2014. https://doi.org/10.1073/pnas.1413559111
  • Perspectives

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      History of vaccination
      Stanley Plotkin
      PNAS August 26, 2014 111 (34) 12283-12287; first published August 18, 2014. https://doi.org/10.1073/pnas.1400472111
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      Vaccines, new opportunities for a new society
      Rino Rappuoli, Mariagrazia Pizza, Giuseppe Del Giudice, and Ennio De Gregorio
      PNAS August 26, 2014 111 (34) 12288-12293; first published August 18, 2014. https://doi.org/10.1073/pnas.1402981111
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      Unleashing the potential of NOD- and Toll-like agonists as vaccine adjuvants
      Charles Maisonneuve, Sylvie Bertholet, Dana J. Philpott, and Ennio De Gregorio
      PNAS August 26, 2014 111 (34) 12294-12299; first published August 18, 2014. https://doi.org/10.1073/pnas.1400478111
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      Systems vaccinology: Probing humanity’s diverse immune systems with vaccines
      Bali Pulendran
      PNAS August 26, 2014 111 (34) 12300-12306; first published August 18, 2014. https://doi.org/10.1073/pnas.1400476111
    • You have access
      Vaccines against poverty
      Calman A. MacLennan and Allan Saul
      PNAS August 26, 2014 111 (34) 12307-12312; first published August 18, 2014. https://doi.org/10.1073/pnas.1400473111
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      Valuing vaccination
      Till Bärnighausen, David E. Bloom, Elizabeth T. Cafiero-Fonseca, and Jennifer Carroll O’Brien
      PNAS August 26, 2014 111 (34) 12313-12319; first published August 18, 2014. https://doi.org/10.1073/pnas.1400475111

Physical Sciences

  • Applied Physical Sciences

    • Open Access
      Single-shot stand-off chemical identification of powders using random Raman lasing
      • From the Cover
      Brett H. Hokr, Joel N. Bixler, Gary D. Noojin, Robert J. Thomas, Benjamin A. Rockwell, Vladislav V. Yakovlev, and Marlan O. Scully
      PNAS August 26, 2014 111 (34) 12320-12324; first published August 11, 2014. https://doi.org/10.1073/pnas.1412535111
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      Collective credit allocation in science
      Hua-Wei Shen and Albert-László Barabási
      PNAS August 26, 2014 111 (34) 12325-12330; first published August 11, 2014. https://doi.org/10.1073/pnas.1401992111
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      A cellular solution to an information-processing problem
      Garud Iyengar and Madan Rao
      PNAS August 26, 2014 111 (34) 12402-12407; first published August 11, 2014. https://doi.org/10.1073/pnas.1406608111
  • Earth, Atmospheric, and Planetary Sciences

    • Open Access
      Quasi-resonant circulation regimes and hemispheric synchronization of extreme weather in boreal summer
      Dim Coumou, Vladimir Petoukhov, Stefan Rahmstorf, Stefan Petri, and Hans Joachim Schellnhuber
      PNAS August 26, 2014 111 (34) 12331-12336; first published August 11, 2014. https://doi.org/10.1073/pnas.1412797111
  • Environmental Sciences

    • Open Access
      The Holocene temperature conundrum
      Zhengyu Liu, Jiang Zhu, Yair Rosenthal, Xu Zhang, Bette L. Otto-Bliesner, Axel Timmermann, Robin S. Smith, Gerrit Lohmann, Weipeng Zheng, and Oliver Elison Timm
      PNAS August 26, 2014 111 (34) E3501-E3505; first published August 11, 2014. https://doi.org/10.1073/pnas.1407229111
  • Physics

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      Fair sampling perspective on an apparent violation of duality
      Eliot Bolduc, Jonathan Leach, Filippo M. Miatto, Gerd Leuchs, and Robert W. Boyd
      PNAS August 26, 2014 111 (34) 12337-12341; first published August 11, 2014. https://doi.org/10.1073/pnas.1400106111
    • You have access
      Coevolutionary information, protein folding landscapes, and the thermodynamics of natural selection
      Faruck Morcos, Nicholas P. Schafer, Ryan R. Cheng, José N. Onuchic, and Peter G. Wolynes
      PNAS August 26, 2014 111 (34) 12408-12413; first published August 11, 2014. https://doi.org/10.1073/pnas.1413575111

Social Sciences

  • Anthropology

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      Drought stress variability in ancient Near Eastern agricultural systems evidenced by δ13C in barley grain
      Simone Riehl, Konstantin E. Pustovoytov, Heike Weippert, Stefan Klett, and Frank Hole
      PNAS August 26, 2014 111 (34) 12348-12353; first published August 11, 2014. https://doi.org/10.1073/pnas.1409516111

      See companion article:

      • Stable isotopes and archaeobotany
        - Nov 03, 2014
  • Sustainability Science

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      Global agriculture and carbon trade-offs
      Justin Andrew Johnson, Carlisle Ford Runge, Benjamin Senauer, Jonathan Foley, and Stephen Polasky
      PNAS August 26, 2014 111 (34) 12342-12347; first published August 11, 2014. https://doi.org/10.1073/pnas.1412835111

Biological Sciences

  • Anthropology

    • Open Access
      Drought stress variability in ancient Near Eastern agricultural systems evidenced by δ13C in barley grain
      Simone Riehl, Konstantin E. Pustovoytov, Heike Weippert, Stefan Klett, and Frank Hole
      PNAS August 26, 2014 111 (34) 12348-12353; first published August 11, 2014. https://doi.org/10.1073/pnas.1409516111

      See companion article:

      • Stable isotopes and archaeobotany
        - Nov 03, 2014
  • Applied Biological Sciences

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      Diversity-oriented combinatorial biosynthesis of benzenediol lactone scaffolds by subunit shuffling of fungal polyketide synthases
      • From the Cover
      Yuquan Xu, Tong Zhou, Shuwei Zhang, Patricia Espinosa-Artiles, Luoyi Wang, Wei Zhang, Min Lin, A. A. Leslie Gunatilaka, Jixun Zhan, and István Molnár
      PNAS August 26, 2014 111 (34) 12354-12359; first published July 21, 2014. https://doi.org/10.1073/pnas.1406999111

      See companion article:

      • Polyketide engineering
        - Aug 12, 2014
    • Open Access
      Hybrid biosynthetic gene therapy vector development and dual engineering capacity
      Charles H. Jones, Anitha Ravikrishnan, Mingfu Chen, Ryan Reddinger, Mahmoud Kamal Ahmadi, Snehal Rane, Anders P. Hakansson, and Blaine A. Pfeifer
      PNAS August 26, 2014 111 (34) 12360-12365; first published August 11, 2014. https://doi.org/10.1073/pnas.1411355111
  • Biochemistry

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      A sequence-specific transcription activator motif and powerful synthetic variants that bind Mediator using a fuzzy protein interface
      Linda Warfield, Lisa M. Tuttle, Derek Pacheco, Rachel E. Klevit, and Steven Hahn
      PNAS August 26, 2014 111 (34) E3506-E3513; first published August 13, 2014. https://doi.org/10.1073/pnas.1412088111
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      Mapping the λ Integrase bridges in the nucleoprotein Holliday junction intermediates of viral integrative and excisive recombination
      Wenjun Tong, David Warren, Nicole E. Seah, Gurunathan Laxmikanthan, Gregory D. Van Duyne, and Arthur Landy
      PNAS August 26, 2014 111 (34) 12366-12371; first published August 11, 2014. https://doi.org/10.1073/pnas.1413007111

      See companion article:

      • Architecture of integrative and excisive complexes
        - Aug 11, 2014
    • Open Access
      Nucleoprotein architectures regulating the directionality of viral integration and excision
      Nicole E. Seah, David Warren, Wenjun Tong, Gurunathan Laxmikanthan, Gregory D. Van Duyne, and Arthur Landy
      PNAS August 26, 2014 111 (34) 12372-12377; first published August 11, 2014. https://doi.org/10.1073/pnas.1413019111

      See companion article:

      • λ Int bridges in Holliday junction complexes
        - Aug 11, 2014
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      EFA6 controls Arf1 and Arf6 activation through a negative feedback loop
      Dominique Padovani, Marcia Folly-Klan, Audrey Labarde, Sonia Boulakirba, Valérie Campanacci, Michel Franco, Mahel Zeghouf, and Jacqueline Cherfils
      PNAS August 26, 2014 111 (34) 12378-12383; first published August 11, 2014. https://doi.org/10.1073/pnas.1409832111
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      α-Fluorophosphonates reveal how a phosphomutase conserves transition state conformation over hexose recognition in its two-step reaction
      Yi Jin, Debabrata Bhattasali, Erika Pellegrini, Stephanie M. Forget, Nicola J. Baxter, Matthew J. Cliff, Matthew W. Bowler, David L. Jakeman, G. Michael Blackburn, and Jonathan P. Waltho
      PNAS August 26, 2014 111 (34) 12384-12389; first published August 7, 2014. https://doi.org/10.1073/pnas.1402850111
    • Open Access
      Chaperone-enhanced purification of unconventional myosin 15, a molecular motor specialized for stereocilia protein trafficking
      Jonathan E. Bird, Yasuharu Takagi, Neil Billington, Marie-Paule Strub, James R. Sellers, and Thomas B. Friedman
      PNAS August 26, 2014 111 (34) 12390-12395; first published August 11, 2014. https://doi.org/10.1073/pnas.1409459111
    • Open Access
      Microbial-induced meprin β cleavage in MUC2 mucin and a functional CFTR channel are required to release anchored small intestinal mucus
      André Schütte, Anna Ermund, Christoph Becker-Pauly, Malin E. V. Johansson, Ana M. Rodriguez-Pineiro, Fredrik Bäckhed, Stefan Müller, Daniel Lottaz, Judith S. Bond, and Gunnar C. Hansson
      PNAS August 26, 2014 111 (34) 12396-12401; first published August 11, 2014. https://doi.org/10.1073/pnas.1407597111
  • Biophysics and Computational Biology

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      Structural basis for the recruitment and activation of the Legionella phospholipase VipD by the host GTPase Rab5
      María Lucas, Andrew H. Gaspar, Chiara Pallara, Adriana Lucely Rojas, Juan Fernández-Recio, Matthias P. Machner, and Aitor Hierro
      PNAS August 26, 2014 111 (34) E3514-E3523; first published August 11, 2014. https://doi.org/10.1073/pnas.1405391111
    • Open Access
      Electron spin changes during general anesthesia in Drosophila
      Luca Turin, Efthimios M. C. Skoulakis, and Andrew P. Horsfield
      PNAS August 26, 2014 111 (34) E3524-E3533; first published August 11, 2014. https://doi.org/10.1073/pnas.1404387111
    • You have access
      A cellular solution to an information-processing problem
      Garud Iyengar and Madan Rao
      PNAS August 26, 2014 111 (34) 12402-12407; first published August 11, 2014. https://doi.org/10.1073/pnas.1406608111
    • You have access
      Coevolutionary information, protein folding landscapes, and the thermodynamics of natural selection
      Faruck Morcos, Nicholas P. Schafer, Ryan R. Cheng, José N. Onuchic, and Peter G. Wolynes
      PNAS August 26, 2014 111 (34) 12408-12413; first published August 11, 2014. https://doi.org/10.1073/pnas.1413575111
    • You have access
      Characterizing the proton loading site in cytochrome c oxidase
      Jianxun Lu and M. R. Gunner
      PNAS August 26, 2014 111 (34) 12414-12419; first published August 11, 2014. https://doi.org/10.1073/pnas.1407187111
    • You have access
      Engineered kinase activation reveals unique morphodynamic phenotypes and associated trafficking for Src family isoforms
      Pei-Hsuan Chu, Denis Tsygankov, Matthew E. Berginski, Onur Dagliyan, Shawn M. Gomez, Timothy C. Elston, Andrei V. Karginov, and Klaus M. Hahn
      PNAS August 26, 2014 111 (34) 12420-12425; first published August 12, 2014. https://doi.org/10.1073/pnas.1404487111
  • Cell Biology

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      Distinct isoform of FABP7 revealed by screening for retroelement-activated genes in diffuse large B-cell lymphoma
      Frances E. Lock, Rita Rebollo, Katharine Miceli-Royer, Liane Gagnier, Sabrina Kuah, Artem Babaian, Maialen Sistiaga-Poveda, C. Benjamin Lai, Oksana Nemirovsky, Isabel Serrano, Christian Steidl, Mohammad M. Karimi, and Dixie L. Mager
      PNAS August 26, 2014 111 (34) E3534-E3543; first published August 11, 2014. https://doi.org/10.1073/pnas.1405507111
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      Calcineurin determines toxic versus beneficial responses to α-synuclein
      Gabriela Caraveo, Pavan K. Auluck, Luke Whitesell, Chee Yeun Chung, Valeriya Baru, Eugene V. Mosharov, Xiaohui Yan, Manu Ben-Johny, Martin Soste, Paola Picotti, Hanna Kim, Kim A. Caldwell, Guy A. Caldwell, David Sulzer, David T. Yue, and Susan Lindquist
      PNAS August 26, 2014 111 (34) E3544-E3552; first published August 13, 2014. https://doi.org/10.1073/pnas.1413201111
    • Open Access
      Dynamic regulation of human endogenous retroviruses mediates factor-induced reprogramming and differentiation potential
      Mari Ohnuki, Koji Tanabe, Kenta Sutou, Ito Teramoto, Yuka Sawamura, Megumi Narita, Michiko Nakamura, Yumie Tokunaga, Masahiro Nakamura, Akira Watanabe, Shinya Yamanaka, and Kazutoshi Takahashi
      PNAS August 26, 2014 111 (34) 12426-12431; first published August 5, 2014. https://doi.org/10.1073/pnas.1413299111
    • Open Access
      Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli
      Francis Impens, Lilliana Radoshevich, Pascale Cossart, and David Ribet
      PNAS August 26, 2014 111 (34) 12432-12437; first published August 11, 2014. https://doi.org/10.1073/pnas.1413825111
  • Developmental Biology

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      Primary cilia are required in a unique subpopulation of neural progenitors
      Cheuk Ka Tong, Young-Goo Han, Jugal K. Shah, Kirsten Obernier, Cristina D. Guinto, and Arturo Alvarez-Buylla
      PNAS August 26, 2014 111 (34) 12438-12443; first published August 11, 2014. https://doi.org/10.1073/pnas.1321425111
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      Wnt ligand/Frizzled 2 receptor signaling regulates tube shape and branch-point formation in the lung through control of epithelial cell shape
      Rachel S. Kadzik, Ethan David Cohen, Michael P. Morley, Kathleen M. Stewart, Min Min Lu, and Edward E. Morrisey
      PNAS August 26, 2014 111 (34) 12444-12449; first published August 11, 2014. https://doi.org/10.1073/pnas.1406639111
  • Genetics

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      Small RNA combination therapy for lung cancer
      Wen Xue, James E. Dahlman, Tuomas Tammela, Omar F. Khan, Sabina Sood, Apeksha Dave, Wenxin Cai, Leilani M. Chirino, Gillian R. Yang, Roderick Bronson, Denise G. Crowley, Gaurav Sahay, Avi Schroeder, Robert Langer, Daniel G. Anderson, and Tyler Jacks
      PNAS August 26, 2014 111 (34) E3553-E3561; first published August 11, 2014. https://doi.org/10.1073/pnas.1412686111
    • You have access
      Molecular pathogenesis of congenital diaphragmatic hernia revealed by exome sequencing, developmental data, and bioinformatics
      Mauro Longoni, Frances A. High, Meaghan K. Russell, Alireza Kashani, Adam A. Tracy, Caroline M. Coletti, Regis Hila, Ahmed Shamia, Julie Wells, Kate G. Ackerman, Jay M. Wilson, Carol J. Bult, Charles Lee, Kasper Lage, Barbara R. Pober, and Patricia K. Donahoe
      PNAS August 26, 2014 111 (34) 12450-12455; first published August 8, 2014. https://doi.org/10.1073/pnas.1412509111
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      Predicting hybrid performance in rice using genomic best linear unbiased prediction
      Shizhong Xu, Dan Zhu, and Qifa Zhang
      PNAS August 26, 2014 111 (34) 12456-12461; first published August 11, 2014. https://doi.org/10.1073/pnas.1413750111
    • Open Access
      Enhanced killing of antibiotic-resistant bacteria enabled by massively parallel combinatorial genetics
      • From the Cover
      Allen A. Cheng, Huiming Ding, and Timothy K. Lu
      PNAS August 26, 2014 111 (34) 12462-12467; first published August 11, 2014. https://doi.org/10.1073/pnas.1400093111
  • Immunology and Inflammation

    • Open Access
      Murine CD27(−) Vγ6(+) γδ T cells producing IL-17A promote ovarian cancer growth via mobilization of protumor small peritoneal macrophages
      Margarida Rei, Natacha Gonçalves-Sousa, Telma Lança, Richard G. Thompson, Sofia Mensurado, Frances R. Balkwill, Hagen Kulbe, Daniel J. Pennington, and Bruno Silva-Santos
      PNAS August 26, 2014 111 (34) E3562-E3570; first published August 11, 2014. https://doi.org/10.1073/pnas.1403424111
    • Open Access
      Small-molecule screening identifies inhibition of salt-inducible kinases as a therapeutic strategy to enhance immunoregulatory functions of dendritic cells
      Thomas B. Sundberg, Hwan Geun Choi, Joo-Hye Song, Caitlin N. Russell, Mahmud M. Hussain, Daniel B. Graham, Bernard Khor, John Gagnon, Daniel J. O’Connell, Kavitha Narayan, Vlado Dančík, Jose R. Perez, Hans-Christian Reinecker, Nathanael S. Gray, Stuart L. Schreiber, Ramnik J. Xavier, and Alykhan F. Shamji
      PNAS August 26, 2014 111 (34) 12468-12473; first published August 11, 2014. https://doi.org/10.1073/pnas.1412308111
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      KLRG+ invariant natural killer T cells are long-lived effectors
      Kanako Shimizu, Yusuke Sato, Jun Shinga, Takashi Watanabe, Takaho Endo, Miki Asakura, Satoru Yamasaki, Kazuyoshi Kawahara, Yuki Kinjo, Hiroshi Kitamura, Hiroshi Watarai, Yasuyuki Ishii, Moriya Tsuji, Masaru Taniguchi, Osamu Ohara, and Shin-ichiro Fujii
      PNAS August 26, 2014 111 (34) 12474-12479; first published August 12, 2014. https://doi.org/10.1073/pnas.1406240111
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      Autophagy protects C. elegans against necrosis during Pseudomonas aeruginosa infection
      Cheng-Gang Zou, Yi-Cheng Ma, Li-Li Dai, and Ke-Qin Zhang
      PNAS August 26, 2014 111 (34) 12480-12485; first published August 11, 2014. https://doi.org/10.1073/pnas.1405032111
  • Medical Sciences

    • Open Access
      Tumorigenicity of hypoxic respiring cancer cells revealed by a hypoxia–cell cycle dual reporter
      Anne Le, Zachary E. Stine, Christopher Nguyen, Junaid Afzal, Peng Sun, Max Hamaker, Nicholas M. Siegel, Arvin M. Gouw, Byung-hak Kang, Shu-Han Yu, Rory L. Cochran, Kurt A. Sailor, Hongjun Song, and Chi V. Dang
      PNAS August 26, 2014 111 (34) 12486-12491; first published August 11, 2014. https://doi.org/10.1073/pnas.1402012111
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      Interleukin-1 deficiency prolongs ovarian lifespan in mice
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      PNAS August 26, 2014 111 (34) 12492-12497; first published August 11, 2014. https://doi.org/10.1073/pnas.1323955111
  • Microbiology

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      Native microbiome impedes vertical transmission of Wolbachia in Anopheles mosquitoes
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      PNAS August 26, 2014 111 (34) 12498-12503; first published August 11, 2014. https://doi.org/10.1073/pnas.1408888111
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      Marine ammonia-oxidizing archaeal isolates display obligate mixotrophy and wide ecotypic variation
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      PNAS August 26, 2014 111 (34) 12504-12509; first published August 11, 2014. https://doi.org/10.1073/pnas.1324115111
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      Compound-gene interaction mapping reveals distinct roles for Staphylococcus aureus teichoic acids
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      PNAS August 26, 2014 111 (34) 12510-12515; first published August 7, 2014. https://doi.org/10.1073/pnas.1404099111
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      Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus
      Yang Yang, Lanying Du, Chang Liu, Lili Wang, Cuiqing Ma, Jian Tang, Ralph S. Baric, Shibo Jiang, and Fang Li
      PNAS August 26, 2014 111 (34) 12516-12521; first published August 11, 2014. https://doi.org/10.1073/pnas.1405889111
    • You have access
      Patterned progression of bacterial populations in the premature infant gut
      Patricio S. La Rosa, Barbara B. Warner, Yanjiao Zhou, George M. Weinstock, Erica Sodergren, Carla M. Hall-Moore, Harold J. Stevens, William E. Bennett Jr., Nurmohammad Shaikh, Laura A. Linneman, Julie A. Hoffmann, Aaron Hamvas, Elena Deych, Berkley A. Shands, William D. Shannon, and Phillip I. Tarr
      PNAS August 26, 2014 111 (34) 12522-12527; first published August 11, 2014. https://doi.org/10.1073/pnas.1409497111
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      Vectored antibody gene delivery protects against Plasmodium falciparum sporozoite challenge in mice
      Cailin Deal, Alejandro B. Balazs, Diego A. Espinosa, Fidel Zavala, David Baltimore, and Gary Ketner
      PNAS August 26, 2014 111 (34) 12528-12532; first published August 11, 2014. https://doi.org/10.1073/pnas.1407362111
  • Neuroscience

    • Open Access
      Socially responsive effects of brain oxidative metabolism on aggression
      Hongmei Li-Byarlay, Clare C. Rittschof, Jonathan H. Massey, Barry R. Pittendrigh, and Gene E. Robinson
      PNAS August 26, 2014 111 (34) 12533-12537; first published August 4, 2014. https://doi.org/10.1073/pnas.1412306111
    • You have access
      Nicotinic and muscarinic agonists and acetylcholinesterase inhibitors stimulate a common pathway to enhance GluN2B-NMDAR responses
      Masaru Ishibashi, Yoshihiko Yamazaki, Ricardo Miledi, and Katumi Sumikawa
      PNAS August 26, 2014 111 (34) 12538-12543; first published August 11, 2014. https://doi.org/10.1073/pnas.1408805111
    • You have access
      DRK/DOS/SOS converge with Crk/Mbc/dCed-12 to activate Rac1 during glial engulfment of axonal debris
      Tsai-Yi Lu, Johnna Doherty, and Marc R. Freeman
      PNAS August 26, 2014 111 (34) 12544-12549; first published August 6, 2014. https://doi.org/10.1073/pnas.1403450111
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      MRI-localized biopsies reveal subtype-specific differences in molecular and cellular composition at the margins of glioblastoma
      Brian J. Gill, David J. Pisapia, Hani R. Malone, Hannah Goldstein, Liang Lei, Adam Sonabend, Jonathan Yun, Jorge Samanamud, Jennifer S. Sims, Matei Banu, Athanassios Dovas, Andrew F. Teich, Sameer A. Sheth, Guy M. McKhann, Michael B. Sisti, Jeffrey N. Bruce, Peter A. Sims, and Peter Canoll
      PNAS August 26, 2014 111 (34) 12550-12555; first published August 11, 2014. https://doi.org/10.1073/pnas.1405839111
  • Pharmacology

    • You have access
      Inhibitor of MYC identified in a Kröhnke pyridine library
      Jonathan R. Hart, Amanda L. Garner, Jing Yu, Yoshihiro Ito, Minghao Sun, Lynn Ueno, Jin-Kyu Rhee, Michael M. Baksh, Eduard Stefan, Markus Hartl, Klaus Bister, Peter K. Vogt, and Kim D. Janda
      PNAS August 26, 2014 111 (34) 12556-12561; first published August 11, 2014. https://doi.org/10.1073/pnas.1319488111
  • Physiology

    • You have access
      Genetic–epigenetic dysregulation of thymic TSH receptor gene expression triggers thyroid autoimmunity
      Mihaela Stefan, Chengguo Wei, Angela Lombardi, Cheuk Wun Li, Erlinda S. Concepcion, William B. Inabnet III, Randall Owen, Weijia Zhang, and Yaron Tomer
      PNAS August 26, 2014 111 (34) 12562-12567; first published August 13, 2014. https://doi.org/10.1073/pnas.1408821111
  • Plant Biology

    • Open Access
      DELAY OF GERMINATION 1 mediates a conserved coat-dormancy mechanism for the temperature- and gibberellin-dependent control of seed germination
      Kai Graeber, Ada Linkies, Tina Steinbrecher, Klaus Mummenhoff, Danuše Tarkowská, Veronika Turečková, Michael Ignatz, Katja Sperber, Antje Voegele, Hans de Jong, Terezie Urbanová, Miroslav Strnad, and Gerhard Leubner-Metzger
      PNAS August 26, 2014 111 (34) E3571-E3580; first published August 11, 2014. https://doi.org/10.1073/pnas.1403851111

Correction

  • You have access
    Correction for Poulson-Ellestad et al., Metabolomics and proteomics reveal impacts of chemically mediated competition on marine plankton
    PNAS August 26, 2014 111 (34) 12568; first published August 11, 2014. https://doi.org/10.1073/pnas.1413432111
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Proceedings of the National Academy of Sciences: 111 (34)
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