New Research In
Physical Sciences
Social Sciences
Featured Portals
Articles by Topic
Biological Sciences
Featured Portals
Articles by Topic
- Agricultural Sciences
- Anthropology
- Applied Biological Sciences
- Biochemistry
- Biophysics and Computational Biology
- Cell Biology
- Developmental Biology
- Ecology
- Environmental Sciences
- Evolution
- Genetics
- Immunology and Inflammation
- Medical Sciences
- Microbiology
- Neuroscience
- Pharmacology
- Physiology
- Plant Biology
- Population Biology
- Psychological and Cognitive Sciences
- Sustainability Science
- Systems Biology
Table of Contents
October 21, 2014; vol. 111 no. 42
This Week in PNAS
Letters (Online Only)
- You have accessGluconeogenesis in cancer: Door wide openKatharina Leithner, Andelko Hrzenjak, and Horst OlschewskiPNAS October 21, 2014 111 (42) E4394; first published September 26, 2014. https://doi.org/10.1073/pnas.1415680111
- You have accessReply to Leithner et al.: Focus on phopshoenolpyruvate carboxykinase (PEPCK): A target of the p53-SIRT6-FoxO1 axisZhiming Li and Wei-Guo ZhuPNAS October 21, 2014 111 (42) E4395; first published September 26, 2014. https://doi.org/10.1073/pnas.1416664111
See companion article:
- p53 activates SIRT6 to regulate gluconeogenesis- Jul 09, 2014
- You have accessStill no convincing evidence for cognitive map use by honeybeesAllen Cheung, Matthew Collett, Thomas S. Collett, Alex Dewar, Fred Dyer, Paul Graham, Michael Mangan, Ajay Narendra, Andrew Philippides, Wolfgang Stürzl, Barbara Webb, Antoine Wystrach, and Jochen ZeilPNAS October 21, 2014 111 (42) E4396-E4397; first published October 2, 2014. https://doi.org/10.1073/pnas.1413581111
- You have accessReply to Cheung et al.: The cognitive map hypothesis remains the best interpretation of the data in honeybee navigationJames F. Cheeseman, Craig D. Millar, Uwe Greggers, Konstantin Lehmann, Matthew D. M. Pawley, Charles R. Gallistel, Guy R. Warman, and Randolf MenzelPNAS October 21, 2014 111 (42) E4398; first published October 2, 2014. https://doi.org/10.1073/pnas.1415738111
See companion article:
- The bee reads its map- Jun 02, 2014
Inner Workings
An over-the-shoulder look at scientists at work.
Retrospective
- You have accessWoody Hastings: 65 years of funE. Peter Greenberg, Kenneth H. Nealson, and Carl Hirschie JohnsonPNAS October 21, 2014 111 (42) 14964-14965; first published September 30, 2014. https://doi.org/10.1073/pnas.1415972111
PNAS Plus Significance Statements
Brief statements written by the authors about the significance of their papers.
Physical Sciences
Applied Mathematics
- You have accessUniversality in numerical computations with random dataPercy A. Deift, Govind Menon, Sheehan Olver, and Thomas TrogdonPNAS October 21, 2014 111 (42) 14973-14978; first published September 24, 2014. https://doi.org/10.1073/pnas.1413446111
Applied Physical Sciences
- You have accessMultivariate biophysical markers predictive of mesenchymal stromal cell multipotencyWong Cheng Lee, Hui Shi, Zhiyong Poon, Lin Myint Nyan, Tanwi Kaushik, G. V. Shivashankar, Jerry K. Y. Chan, Chwee Teck Lim, Jongyoon Han, and Krystyn J. Van VlietPNAS October 21, 2014 111 (42) E4409-E4418; first published October 8, 2014. https://doi.org/10.1073/pnas.1402306111
- Open AccessIntrinsic conduction through topological surface states of insulating Bi2Te3 epitaxial thin filmsKatharina Hoefer, Christoph Becker, Diana Rata, Jesse Swanson, Peter Thalmeier, and L. H. TjengPNAS October 21, 2014 111 (42) 14979-14984; first published October 7, 2014. https://doi.org/10.1073/pnas.1410591111
Chemistry
- You have accessLabel-free electrochemical detection of human methyltransferase from tumorsAriel L. Furst, Natalie B. Muren, Michael G. Hill, and Jacqueline K. BartonPNAS October 21, 2014 111 (42) 14985-14989; first published October 6, 2014. https://doi.org/10.1073/pnas.1417351111
- You have accessUltraefficient homogeneous catalyst for the CO2-to-CO electrochemical conversion
- From the Cover
Cyrille Costentin, Guillaume Passard, Marc Robert, and Jean-Michel SavéantPNAS October 21, 2014 111 (42) 14990-14994; first published October 6, 2014. https://doi.org/10.1073/pnas.1416697111 - You have accessImportance of the DNA “bond” in programmable nanoparticle crystallizationRobert J. Macfarlane, Ryan V. Thaner, Keith A. Brown, Jian Zhang, Byeongdu Lee, SonBinh T. Nguyen, and Chad A. MirkinPNAS October 21, 2014 111 (42) 14995-15000; first published October 8, 2014. https://doi.org/10.1073/pnas.1416489111
- Open AccessRole of pendant proton relays and proton-coupled electron transfer on the hydrogen evolution reaction by nickel hangman porphyrinsD. Kwabena Bediako, Brian H. Solis, Dilek K. Dogutan, Manolis M. Roubelakis, Andrew G. Maher, Chang Hoon Lee, Matthew B. Chambers, Sharon Hammes-Schiffer, and Daniel G. NoceraPNAS October 21, 2014 111 (42) 15001-15006; first published October 8, 2014. https://doi.org/10.1073/pnas.1414908111
- You have accessApplication of desorption electrospray ionization mass spectrometry imaging in breast cancer margin analysisDavid Calligaris, Diana Caragacianu, Xiaohui Liu, Isaiah Norton, Christopher J. Thompson, Andrea L. Richardson, Mehra Golshan, Michael L. Easterling, Sandro Santagata, Deborah A. Dillon, Ferenc A. Jolesz, and Nathalie Y. R. AgarPNAS October 21, 2014 111 (42) 15184-15189; first published September 22, 2014. https://doi.org/10.1073/pnas.1408129111
Earth, Atmospheric, and Planetary Sciences
- You have accessThe negligible chondritic contribution in the lunar soils waterAlice Stephant and François RobertPNAS October 21, 2014 111 (42) 15007-15012; first published October 6, 2014. https://doi.org/10.1073/pnas.1408118111
Engineering
- You have accessDiscrete elements for 3D microfluidics
- From the Cover
Krisna C. Bhargava, Bryant Thompson, and Noah MalmstadtPNAS October 21, 2014 111 (42) 15013-15018; first published September 22, 2014. https://doi.org/10.1073/pnas.1414764111
Environmental Sciences
- Open AccessNeutral molecular cluster formation of sulfuric acid–dimethylamine observed in real time under atmospheric conditionsAndreas Kürten, Tuija Jokinen, Mario Simon, Mikko Sipilä, Nina Sarnela, Heikki Junninen, Alexey Adamov, João Almeida, Antonio Amorim, Federico Bianchi, Martin Breitenlechner, Josef Dommen, Neil M. Donahue, Jonathan Duplissy, Sebastian Ehrhart, Richard C. Flagan, Alessandro Franchin, Jani Hakala, Armin Hansel, Martin Heinritzi, Manuel Hutterli, Juha Kangasluoma, Jasper Kirkby, Ari Laaksonen, Katrianne Lehtipalo, Markus Leiminger, Vladimir Makhmutov, Serge Mathot, Antti Onnela, Tuukka Petäjä, Arnaud P. Praplan, Francesco Riccobono, Matti P. Rissanen, Linda Rondo, Siegfried Schobesberger, John H. Seinfeld, Gerhard Steiner, António Tomé, Jasmin Tröstl, Paul M. Winkler, Christina Williamson, Daniela Wimmer, Penglin Ye, Urs Baltensperger, Kenneth S. Carslaw, Markku Kulmala, Douglas R. Worsnop, and Joachim CurtiusPNAS October 21, 2014 111 (42) 15019-15024; first published October 6, 2014. https://doi.org/10.1073/pnas.1404853111
Physics
- You have accessHopping and the Stokes–Einstein relation breakdown in simple glass formersPatrick Charbonneau, Yuliang Jin, Giorgio Parisi, and Francesco ZamponiPNAS October 21, 2014 111 (42) 15025-15030; first published October 6, 2014. https://doi.org/10.1073/pnas.1417182111
- You have accessPart-crystalline part-liquid state and rattling-like thermal damping in materials with chemical-bond hierarchyWujie Qiu, Lili Xi, Ping Wei, Xuezhi Ke, Jihui Yang, and Wenqing ZhangPNAS October 21, 2014 111 (42) 15031-15035; first published October 6, 2014. https://doi.org/10.1073/pnas.1410349111
Sustainability Science
- You have accessTracking sustainable development with a national barometer for South Africa using a downscaled “safe and just space” frameworkMegan J. Cole, Richard M. Bailey, and Mark G. NewPNAS October 21, 2014 111 (42) E4399-E4408; first published October 7, 2014. https://doi.org/10.1073/pnas.1400985111
Social Sciences
Psychological and Cognitive Sciences
- You have accessUniversality in numerical computations with random dataPercy A. Deift, Govind Menon, Sheehan Olver, and Thomas TrogdonPNAS October 21, 2014 111 (42) 14973-14978; first published September 24, 2014. https://doi.org/10.1073/pnas.1413446111
- You have accessNeural and cognitive characteristics of extraordinary altruists
- From the Cover
- Cozzarelli Prize Winner
Abigail A. Marsh, Sarah A. Stoycos, Kristin M. Brethel-Haurwitz, Paul Robinson, John W. VanMeter, and Elise M. CardinalePNAS October 21, 2014 111 (42) 15036-15041; first published September 15, 2014. https://doi.org/10.1073/pnas.1408440111See companion article:
- From fear recognition to kidney donation- Oct 09, 2014
Sustainability Science
- You have accessTracking sustainable development with a national barometer for South Africa using a downscaled “safe and just space” frameworkMegan J. Cole, Richard M. Bailey, and Mark G. NewPNAS October 21, 2014 111 (42) E4399-E4408; first published October 7, 2014. https://doi.org/10.1073/pnas.1400985111
- You have accessPublic awareness, concerns, and priorities about anthropogenic impacts on marine environmentsStefan Gelcich, Paul Buckley, John K. Pinnegar, Jason Chilvers, Irene Lorenzoni, Geraldine Terry, Matias Guerrero, Juan Carlos Castilla, Abel Valdebenito, and Carlos M. DuartePNAS October 21, 2014 111 (42) 15042-15047; first published October 6, 2014. https://doi.org/10.1073/pnas.1417344111
Biological Sciences
Applied Biological Sciences
- You have accessMultivariate biophysical markers predictive of mesenchymal stromal cell multipotencyWong Cheng Lee, Hui Shi, Zhiyong Poon, Lin Myint Nyan, Tanwi Kaushik, G. V. Shivashankar, Jerry K. Y. Chan, Chwee Teck Lim, Jongyoon Han, and Krystyn J. Van VlietPNAS October 21, 2014 111 (42) E4409-E4418; first published October 8, 2014. https://doi.org/10.1073/pnas.1402306111
- You have accessIntrinsic disorder as a generalizable strategy for the rational design of highly responsive, allosterically cooperative receptorsAnna J. Simon, Alexis Vallée-Bélisle, Francesco Ricci, and Kevin W. PlaxcoPNAS October 21, 2014 111 (42) 15048-15053; first published October 6, 2014. https://doi.org/10.1073/pnas.1410796111
Biochemistry
- You have accessLabel-free electrochemical detection of human methyltransferase from tumorsAriel L. Furst, Natalie B. Muren, Michael G. Hill, and Jacqueline K. BartonPNAS October 21, 2014 111 (42) 14985-14989; first published October 6, 2014. https://doi.org/10.1073/pnas.1417351111
- Open AccessThe signaling phospholipid PIP3 creates a new interaction surface on the nuclear receptor SF-1Raymond D. Blind, Elena P. Sablin, Kristopher M. Kuchenbecker, Hsiu-Ju Chiu, Ashley M. Deacon, Debanu Das, Robert J. Fletterick, and Holly A. IngrahamPNAS October 21, 2014 111 (42) 15054-15059; first published October 6, 2014. https://doi.org/10.1073/pnas.1416740111
- You have accessFollowing movement of domain IV of elongation factor G during ribosomal translocationEnea Salsi, Elie Farah, Jillian Dann, and Dmitri N. ErmolenkoPNAS October 21, 2014 111 (42) 15060-15065; first published October 6, 2014. https://doi.org/10.1073/pnas.1410873111
- You have accessInvestigating the role of a backbone to substrate hydrogen bond in OMP decarboxylase using a site-specific amide to ester substitutionBijoy J. Desai, Yuki Goto, Alessandro Cembran, Alexander A. Fedorov, Steven C. Almo, Jiali Gao, Hiroaki Suga, and John A. GerltPNAS October 21, 2014 111 (42) 15066-15071; first published October 1, 2014. https://doi.org/10.1073/pnas.1411772111
- You have accessActivation of the pseudokinase MLKL unleashes the four-helix bundle domain to induce membrane localization and necroptotic cell deathJoanne M. Hildebrand, Maria C. Tanzer, Isabelle S. Lucet, Samuel N. Young, Sukhdeep K. Spall, Pooja Sharma, Catia Pierotti, Jean-Marc Garnier, Renwick C. J. Dobson, Andrew I. Webb, Anne Tripaydonis, Jeffrey J. Babon, Mark D. Mulcair, Martin J. Scanlon, Warren S. Alexander, Andrew F. Wilks, Peter E. Czabotar, Guillaume Lessene, James M. Murphy, and John SilkePNAS October 21, 2014 111 (42) 15072-15077; first published October 6, 2014. https://doi.org/10.1073/pnas.1408987111
- You have accessKAISO, a critical regulator of p53-mediated transcription of CDKN1A and apoptotic genesDong-In Koh, Dohyun Han, Hoon Ryu, Won-Il Choi, Bu-Nam Jeon, Min-Kyeong Kim, Youngsoo Kim, Jin Young Kim, Lee Parry, Alan R. Clarke, Albert B. Reynolds, and Man-Wook HurPNAS October 21, 2014 111 (42) 15078-15083; first published October 6, 2014. https://doi.org/10.1073/pnas.1318780111
- You have accessStructure of the ArgRS–GlnRS–AIMP1 complex and its implications for mammalian translationYaoyao Fu, Youngran Kim, Kyeong Sik Jin, Hyun Sook Kim, Jong Hyun Kim, DongMing Wang, Minyoung Park, Chang Hwa Jo, Nam Hoon Kwon, Doyeun Kim, Myung Hee Kim, Young Ho Jeon, Kwang Yeon Hwang, Sunghoon Kim, and Yunje ChoPNAS October 21, 2014 111 (42) 15084-15089; first published October 6, 2014. https://doi.org/10.1073/pnas.1408836111
Biophysics and Computational Biology
- You have accessConformational coupling between the active site and residues within the KC-channel of the Vibrio cholerae cbb3-type (C-family) oxygen reductaseYoung O. Ahn, Paween Mahinthichaichan, Hyun Ju Lee, Hanlin Ouyang, Daniel Kaluka, Syun-Ru Yeh, Davinia Arjona, Denis L. Rousseau, Emad Tajkhorshid, Pia Ädelroth, and Robert B. GennisPNAS October 21, 2014 111 (42) E4419-E4428; first published October 6, 2014. https://doi.org/10.1073/pnas.1411676111
- You have accessVisualization and quantification of nascent RAD51 filament formation at single-monomer resolutionAndrea Candelli, Jan Thomas Holthausen, Martin Depken, Ineke Brouwer, Mariëlla A. M. Franker, Margherita Marchetti, Iddo Heller, Stéphanie Bernard, Edwige B. Garcin, Mauro Modesti, Claire Wyman, Gijs J. L. Wuite, and Erwin J. G. PetermanPNAS October 21, 2014 111 (42) 15090-15095; first published October 6, 2014. https://doi.org/10.1073/pnas.1307824111
- You have accessSingle-molecule packaging initiation in real time by a viral DNA packaging machine from bacteriophage T4Reza Vafabakhsh, Kiran Kondabagil, Tyler Earnest, Kyung Suk Lee, Zhihong Zhang, Li Dai, Karin A. Dahmen, Venigalla B. Rao, and Taekjip HaPNAS October 21, 2014 111 (42) 15096-15101; first published October 6, 2014. https://doi.org/10.1073/pnas.1407235111
- You have accessComputational design of a self-assembling symmetrical β-propeller proteinArnout R. D. Voet, Hiroki Noguchi, Christine Addy, David Simoncini, Daiki Terada, Satoru Unzai, Sam-Yong Park, Kam Y. J. Zhang, and Jeremy R. H. TamePNAS October 21, 2014 111 (42) 15102-15107; first published October 6, 2014. https://doi.org/10.1073/pnas.1412768111
Cell Biology
- You have accessRole of Erbin in ErbB2-dependent breast tumor growthYanmei Tao, Chengyong Shen, Shiwen Luo, Wilfried Traoré, Sylvie Marchetto, Marie-Josée Santoni, Linlin Xu, Biao Wu, Chao Shi, Jinghong Mei, Ryan Bates, Xihui Liu, Kai Zhao, Wen-Cheng Xiong, Jean-Paul Borg, and Lin MeiPNAS October 21, 2014 111 (42) E4429-E4438; first published October 6, 2014. https://doi.org/10.1073/pnas.1407139111
- You have accessOptineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutationYvette C. Wong and Erika L. F. HolzbaurPNAS October 21, 2014 111 (42) E4439-E4448; first published October 7, 2014. https://doi.org/10.1073/pnas.1405752111
- You have accessEstrogen-related receptor α decreases RHOA stability to induce orientated cell migrationJuliette Sailland, Violaine Tribollet, Christelle Forcet, Cyrielle Billon, Bruno Barenton, Julie Carnesecchi, Alice Bachmann, Karine Cécile Gauthier, Shan Yu, Vincent Giguère, Franky L. Chan, and Jean-Marc VanackerPNAS October 21, 2014 111 (42) 15108-15113; first published October 6, 2014. https://doi.org/10.1073/pnas.1402094111
- You have accessBifunctional ectodermal stem cells around the nail display dual fate homeostasis and adaptive wounding response toward nail regeneration
- From the Cover
Yvonne Leung, Eve Kandyba, Yi-Bu Chen, Seth Ruffins, Cheng-Ming Chuong, and Krzysztof KobielakPNAS October 21, 2014 111 (42) 15114-15119; first published October 2, 2014. https://doi.org/10.1073/pnas.1318848111
Ecology
- You have accessRecent mountain pine beetle outbreaks, wildfire severity, and postfire tree regeneration in the US Northern RockiesBrian J. Harvey, Daniel C. Donato, and Monica G. TurnerPNAS October 21, 2014 111 (42) 15120-15125; first published September 29, 2014. https://doi.org/10.1073/pnas.1411346111
- Open AccessBehavior of bats at wind turbinesPaul. M. Cryan, P. Marcos Gorresen, Cris D. Hein, Michael R. Schirmacher, Robert H. Diehl, Manuela M. Huso, David T. S. Hayman, Paul D. Fricker, Frank J. Bonaccorso, Douglas H. Johnson, Kevin Heist, and David C. DaltonPNAS October 21, 2014 111 (42) 15126-15131; first published September 29, 2014. https://doi.org/10.1073/pnas.1406672111
Evolution
- You have accessOccupation of bare habitats, an evolutionary precursor to soil specialization in plants
- From the Cover
N. Ivalú Cacho and Sharon Y. StraussPNAS October 21, 2014 111 (42) 15132-15137; first published September 29, 2014. https://doi.org/10.1073/pnas.1409242111See companion article:
- Evolution of edaphic endemics- Oct 13, 2014
- You have accessTug-of-war between driver and passenger mutations in cancer and other adaptive processesChristopher D. McFarland, Leonid A. Mirny, and Kirill S. KorolevPNAS October 21, 2014 111 (42) 15138-15143; first published October 2, 2014. https://doi.org/10.1073/pnas.1404341111
- You have accessSexual selection on wing interference patterns in Drosophila melanogasterNatsu Katayama, Jessica K. Abbott, Jostein Kjærandsen, Yuma Takahashi, and Erik I. SvenssonPNAS October 21, 2014 111 (42) 15144-15148; first published October 7, 2014. https://doi.org/10.1073/pnas.1407595111
- Open AccessAllopolyploidy, diversification, and the Miocene grassland expansionMatt C. Estep, Michael R. McKain, Dilys Vela Diaz, Jinshun Zhong, John G. Hodge, Trevor R. Hodkinson, Daniel J. Layton, Simon T. Malcomber, Rémy Pasquet, and Elizabeth A. KelloggPNAS October 21, 2014 111 (42) 15149-15154; first published October 6, 2014. https://doi.org/10.1073/pnas.1404177111
Genetics
- You have accessQuantitation of interactions between two DNA loops demonstrates loop domain insulation in E. coli cellsDavid G. Priest, Sandip Kumar, Yan Yan, David D. Dunlap, Ian B. Dodd, and Keith E. ShearwinPNAS October 21, 2014 111 (42) E4449-E4457; first published October 6, 2014. https://doi.org/10.1073/pnas.1410764111
- You have accessFeedback regulation via AMPK and HIF-1 mediates ROS-dependent longevity in Caenorhabditis elegansAra B. Hwang, Eun-A Ryu, Murat Artan, Hsin-Wen Chang, Mohammad Humayun Kabir, Hyun-Jun Nam, Dongyeop Lee, Jae-Seong Yang, Sanguk Kim, William B. Mair, Cheolju Lee, Siu Sylvia Lee, and Seung-Jae LeePNAS October 21, 2014 111 (42) E4458-E4467; first published October 6, 2014. https://doi.org/10.1073/pnas.1411199111
- You have accessCHD8 regulates neurodevelopmental pathways associated with autism spectrum disorder in neural progenitorsAarathi Sugathan, Marta Biagioli, Christelle Golzio, Serkan Erdin, Ian Blumenthal, Poornima Manavalan, Ashok Ragavendran, Harrison Brand, Diane Lucente, Judith Miles, Steven D. Sheridan, Alexei Stortchevoi, Manolis Kellis, Stephen J. Haggarty, Nicholas Katsanis, James F. Gusella, and Michael E. TalkowskiPNAS October 21, 2014 111 (42) E4468-E4477; first published October 7, 2014. https://doi.org/10.1073/pnas.1405266111
- You have accessLoss of p53 induces cell proliferation via Ras-independent activation of the Raf/Mek/Erk signaling pathwayMatthias Drosten, Eleanor Y. M. Sum, Carmen G. Lechuga, Lucía Simón-Carrasco, Harrys K. C. Jacob, Raquel García-Medina, Sidong Huang, Roderick L. Beijersbergen, Rene Bernards, and Mariano BarbacidPNAS October 21, 2014 111 (42) 15155-15160; first published October 6, 2014. https://doi.org/10.1073/pnas.1417549111
- You have accessAutism spectrum disorder severity reflects the average contribution of de novo and familial influencesElise B. Robinson, Kaitlin E. Samocha, Jack A. Kosmicki, Lauren McGrath, Benjamin M. Neale, Roy H. Perlis, and Mark J. DalyPNAS October 21, 2014 111 (42) 15161-15165; first published October 6, 2014. https://doi.org/10.1073/pnas.1409204111
- You have accessRole for LSM genes in the regulation of circadian rhythmsSoledad Perez-Santángelo, Estefanía Mancini, Lauren J. Francey, Ruben Gustavo Schlaen, Ariel Chernomoretz, John B. Hogenesch, and Marcelo J. YanovskyPNAS October 21, 2014 111 (42) 15166-15171; first published October 6, 2014. https://doi.org/10.1073/pnas.1409791111
- Open AccessExome sequencing identifies FANCM as a susceptibility gene for triple-negative breast cancerJohanna I. Kiiski, Liisa M. Pelttari, Sofia Khan, Edda S. Freysteinsdottir, Inga Reynisdottir, Steven N. Hart, Hermela Shimelis, Sara Vilske, Anne Kallioniemi, Johanna Schleutker, Arto Leminen, Ralf Bützow, Carl Blomqvist, Rosa B. Barkardottir, Fergus J. Couch, Kristiina Aittomäki, and Heli NevanlinnaPNAS October 21, 2014 111 (42) 15172-15177; first published October 6, 2014. https://doi.org/10.1073/pnas.1407909111
Immunology and Inflammation
- You have accessHuman TLR10 is an anti-inflammatory pattern-recognition receptorMarije Oosting, Shih-Chin Cheng, Judith M. Bolscher, Rachel Vestering-Stenger, Theo S. Plantinga, Ineke C. Verschueren, Peer Arts, Anja Garritsen, Hans van Eenennaam, Patrick Sturm, Bart-Jan Kullberg, Alexander Hoischen, Gosse J. Adema, Jos W. M. van der Meer, Mihai G. Netea, and Leo A. B. JoostenPNAS October 21, 2014 111 (42) E4478-E4484; first published October 6, 2014. https://doi.org/10.1073/pnas.1410293111
- Open AccessIntestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severitySophie Leclercq, Sébastien Matamoros, Patrice D. Cani, Audrey M. Neyrinck, François Jamar, Peter Stärkel, Karen Windey, Valentina Tremaroli, Fredrik Bäckhed, Kristin Verbeke, Philippe de Timary, and Nathalie M. DelzennePNAS October 21, 2014 111 (42) E4485-E4493; first published October 6, 2014. https://doi.org/10.1073/pnas.1415174111
- You have accessSuppression of antigen-specific adaptive immunity by IL-37 via induction of tolerogenic dendritic cellsYuchun Luo, Xiangna Cai, Sucai Liu, Sen Wang, Claudia A. Nold-Petry, Marcel F. Nold, Philip Bufler, David Norris, Charles A. Dinarello, and Mayumi FujitaPNAS October 21, 2014 111 (42) 15178-15183; first published October 7, 2014. https://doi.org/10.1073/pnas.1416714111
Medical Sciences
- You have accessLEOPARD syndrome-associated SHP2 mutation confers leanness and protection from diet-induced obesityMylène Tajan, Aurélie Batut, Thomas Cadoudal, Simon Deleruyelle, Sophie Le Gonidec, Céline Saint Laurent, Maëlle Vomscheid, Estelle Wanecq, Karine Tréguer, Audrey De Rocca Serra-Nédélec, Claire Vinel, Marie-Adeline Marques, Joffrey Pozzo, Oksana Kunduzova, Jean-Pierre Salles, Maithé Tauber, Patrick Raynal, Hélène Cavé, Thomas Edouard, Philippe Valet, and Armelle YartPNAS October 21, 2014 111 (42) E4494-E4503; first published October 6, 2014. https://doi.org/10.1073/pnas.1406107111
- You have accessIdentification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancersYuan Lin, Haipeng Zhang, Jiankai Liang, Kai Li, Wenbo Zhu, Liwu Fu, Fang Wang, Xiaoke Zheng, Huijuan Shi, Sihan Wu, Xiao Xiao, Lijun Chen, Lipeng Tang, Min Yan, Xiaoxiao Yang, Yaqian Tan, Pengxin Qiu, Yijun Huang, Wei Yin, Xinwen Su, Haiyan Hu, Jun Hu, and Guangmei YanPNAS October 21, 2014 111 (42) E4504-E4512; first published October 6, 2014. https://doi.org/10.1073/pnas.1408759111
- Open AccessMapping of transcription factor motifs in active chromatin identifies IRF5 as key regulator in classical Hodgkin lymphomaStephan Kreher, M. Amine Bouhlel, Pierre Cauchy, Björn Lamprecht, Shuang Li, Michael Grau, Franziska Hummel, Karl Köchert, Ioannis Anagnostopoulos, Korinna Jöhrens, Michael Hummel, John Hiscott, Sören-Sebastian Wenzel, Peter Lenz, Markus Schneider, Ralf Küppers, Claus Scheidereit, Maciej Giefing, Reiner Siebert, Klaus Rajewsky, Georg Lenz, Peter N. Cockerill, Martin Janz, Bernd Dörken, Constanze Bonifer, and Stephan MathasPNAS October 21, 2014 111 (42) E4513-E4522; first published October 6, 2014. https://doi.org/10.1073/pnas.1406985111
- You have accessPGC-1β promotes enterocyte lifespan and tumorigenesis in the intestineElena Bellafante, Annalisa Morgano, Lorena Salvatore, Stefania Murzilli, Giuseppe Di Tullio, Andria D’Orazio, Dominga Latorre, Gaetano Villani, and Antonio MoschettaPNAS October 21, 2014 111 (42) E4523-E4531; first published October 6, 2014. https://doi.org/10.1073/pnas.1415279111
- You have accessApplication of desorption electrospray ionization mass spectrometry imaging in breast cancer margin analysisDavid Calligaris, Diana Caragacianu, Xiaohui Liu, Isaiah Norton, Christopher J. Thompson, Andrea L. Richardson, Mehra Golshan, Michael L. Easterling, Sandro Santagata, Deborah A. Dillon, Ferenc A. Jolesz, and Nathalie Y. R. AgarPNAS October 21, 2014 111 (42) 15184-15189; first published September 22, 2014. https://doi.org/10.1073/pnas.1408129111
- You have accessJAK2V617F promotes replication fork stalling with disease-restricted impairment of the intra-S checkpoint responseEdwin Chen, Jong Sook Ahn, Charlie E. Massie, David Clynes, Anna L. Godfrey, Juan Li, Hyun Jung Park, Jyoti Nangalia, Yvonne Silber, Ann Mullally, Richard J. Gibbons, and Anthony R. GreenPNAS October 21, 2014 111 (42) 15190-15195; first published October 6, 2014. https://doi.org/10.1073/pnas.1401873111
- Open AccessDefects in T-tubular electrical activity underlie local alterations of calcium release in heart failureClaudia Crocini, Raffaele Coppini, Cecilia Ferrantini, Ping Yan, Leslie M. Loew, Chiara Tesi, Elisabetta Cerbai, Corrado Poggesi, Francesco S. Pavone, and Leonardo SacconiPNAS October 21, 2014 111 (42) 15196-15201; first published October 6, 2014. https://doi.org/10.1073/pnas.1411557111
Microbiology
- You have accessBloom of resident antibiotic-resistant bacteria in soil following manure fertilizationNikolina Udikovic-Kolic, Fabienne Wichmann, Nichole A. Broderick, and Jo HandelsmanPNAS October 21, 2014 111 (42) 15202-15207; first published October 6, 2014. https://doi.org/10.1073/pnas.1409836111
- You have accessStructural studies on the authentic mumps virus nucleocapsid showing uncoiling by the phosphoproteinRobert Cox, Adrian Pickar, Shihong Qiu, Jun Tsao, Cynthia Rodenburg, Terje Dokland, Andrew Elson, Biao He, and Ming LuoPNAS October 21, 2014 111 (42) 15208-15213; first published October 6, 2014. https://doi.org/10.1073/pnas.1413268111
- You have accessHost cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike proteinJean Kaoru Millet and Gary R. WhittakerPNAS October 21, 2014 111 (42) 15214-15219; first published October 6, 2014. https://doi.org/10.1073/pnas.1407087111
Neuroscience
- Open AccessAutism as a disorder of predictionPawan Sinha, Margaret M. Kjelgaard, Tapan K. Gandhi, Kleovoulos Tsourides, Annie L. Cardinaux, Dimitrios Pantazis, Sidney P. Diamond, and Richard M. HeldPNAS October 21, 2014 111 (42) 15220-15225; first published October 6, 2014. https://doi.org/10.1073/pnas.1416797111
- You have accessNetrin-4 regulates thalamocortical axon branching in an activity-dependent fashionYasufumi Hayano, Kensuke Sasaki, Nami Ohmura, Makoto Takemoto, Yurie Maeda, Toshihide Yamashita, Yoshio Hata, Kazuhiro Kitada, and Nobuhiko YamamotoPNAS October 21, 2014 111 (42) 15226-15231; first published October 6, 2014. https://doi.org/10.1073/pnas.1402095111
- You have accessGABAB(1) receptor subunit isoforms differentially regulate stress resilienceOlivia F. O’Leary, Daniela Felice, Stefano Galimberti, Hélène M. Savignac, Javier A. Bravo, Tadhg Crowley, Malika El Yacoubi, Jean-Marie Vaugeois, Martin Gassmann, Bernhard Bettler, Timothy G. Dinan, and John F. CryanPNAS October 21, 2014 111 (42) 15232-15237; first published October 6, 2014. https://doi.org/10.1073/pnas.1404090111
- Open AccessLeft–right dissociation of hippocampal memory processes in miceOlivia A. Shipton, Mohamady El-Gaby, John Apergis-Schoute, Karl Deisseroth, David M. Bannerman, Ole Paulsen, and Michael M. KohlPNAS October 21, 2014 111 (42) 15238-15243; first published September 22, 2014. https://doi.org/10.1073/pnas.1405648111
- Open AccessCross-modal effects of value on perceptual acuity and stimulus encodingArezoo Pooresmaeili, Thomas H. B. FitzGerald, Dominik R. Bach, Ulf Toelch, Florian Ostendorf, and Raymond J. DolanPNAS October 21, 2014 111 (42) 15244-15249; first published October 6, 2014. https://doi.org/10.1073/pnas.1408873111
Physiology
- You have accessGenetically enhancing mitochondrial antioxidant activity improves muscle function in agingAlisa Umanskaya, Gaetano Santulli, Wenjun Xie, Daniel C. Andersson, Steven R. Reiken, and Andrew R. MarksPNAS October 21, 2014 111 (42) 15250-15255; first published October 6, 2014. https://doi.org/10.1073/pnas.1412754111
- Open AccessCold and hunger induce diurnality in a nocturnal mammalVincent van der Vinne, Sjaak J. Riede, Jenke A. Gorter, Willem G. Eijer, Michael T. Sellix, Michael Menaker, Serge Daan, Violetta Pilorz, and Roelof A. HutPNAS October 21, 2014 111 (42) 15256-15260; first published October 6, 2014. https://doi.org/10.1073/pnas.1413135111
Plant Biology
- You have accessStructural basis of the regulatory mechanism of the plant CIPK family of protein kinases controlling ion homeostasis and abiotic stressAntonio Chaves-Sanjuan, Maria Jose Sanchez-Barrena, Juana Maria Gonzalez-Rubio, Maria Moreno, Paula Ragel, Marta Jimenez, Jose M. Pardo, Martin Martinez-Ripoll, Francisco J. Quintero, and Armando AlbertPNAS October 21, 2014 111 (42) E4532-E4541; first published October 6, 2014. https://doi.org/10.1073/pnas.1407610111
- You have accessA receptor-like protein mediates the response to pectin modification by activating brassinosteroid signalingSebastian Wolf, Dieuwertje van der Does, Friederike Ladwig, Carsten Sticht, Andreas Kolbeck, Ann-Kathrin Schürholz, Sebastian Augustin, Nana Keinath, Thomas Rausch, Steffen Greiner, Karin Schumacher, Klaus Harter, Cyril Zipfel, and Herman HöftePNAS October 21, 2014 111 (42) 15261-15266; first published October 6, 2014. https://doi.org/10.1073/pnas.1322979111
- You have accessNitrate foraging by Arabidopsis roots is mediated by the transcription factor TCP20 through the systemic signaling pathwayPeizhu Guan, Rongchen Wang, Philippe Nacry, Ghislain Breton, Steve A. Kay, Jose L. Pruneda-Paz, Ariea Davani, and Nigel M. CrawfordPNAS October 21, 2014 111 (42) 15267-15272; first published October 6, 2014. https://doi.org/10.1073/pnas.1411375111
Psychological and Cognitive Sciences
- You have accessNeural and cognitive characteristics of extraordinary altruists
- From the Cover
- Cozzarelli Prize Winner
Abigail A. Marsh, Sarah A. Stoycos, Kristin M. Brethel-Haurwitz, Paul Robinson, John W. VanMeter, and Elise M. CardinalePNAS October 21, 2014 111 (42) 15036-15041; first published September 15, 2014. https://doi.org/10.1073/pnas.1408440111See companion article:
- From fear recognition to kidney donation- Oct 09, 2014
- Open AccessThe high heritability of educational achievement reflects many genetically influenced traits, not just intelligenceEva Krapohl, Kaili Rimfeld, Nicholas G. Shakeshaft, Maciej Trzaskowski, Andrew McMillan, Jean-Baptiste Pingault, Kathryn Asbury, Nicole Harlaar, Yulia Kovas, Philip S. Dale, and Robert PlominPNAS October 21, 2014 111 (42) 15273-15278; first published October 6, 2014. https://doi.org/10.1073/pnas.1408777111
Correction
- You have accessCorrection for Betts et al., Contrasted coevolutionary dynamics between a bacterial pathogen and its bacteriophagesPNAS October 21, 2014 111 (42) 15279; first published September 30, 2014. https://doi.org/10.1073/pnas.1418380111
Commentaries
See companion article:
See companion article: