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Meal frequency and timing in health and disease

Mark P. Mattson, David B. Allison, Luigi Fontana, Michelle Harvie, Valter D. Longo, Willy J. Malaisse, Michael Mosley, Lucia Notterpek, Eric Ravussin, Frank A. J. L. Scheer, Thomas N. Seyfried, Krista A. Varady, and Satchidananda Panda
PNAS November 25, 2014 111 (47) 16647-16653; published ahead of print November 17, 2014 https://doi.org/10.1073/pnas.1413965111
Mark P. Mattson
aLaboratory of Neurosciences, National Institute on Aging, Baltimore, MD 21224;bDepartment of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD 21205;
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  • For correspondence: mark.mattson@nih.govpanda@salk.edu
David B. Allison
cNutrition and Obesity Research Center, University of Alabama at Birmingham, Birmingham, AL 35294;
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Luigi Fontana
dDepartment of Medicine, Washington University in St. Louis, St. Louis, MO 63130;eDepartment of Clinical and Experimental Sciences, Brescia University, 25123 Brescia, Italy;fCEINGE Biotecnologie Avanzate, 80145 Naples, Italy;
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Michelle Harvie
gGenesis Breast Cancer Prevention Centre, University Hospital South Manchester, Wythenshaw, M23 9LT Manchester, United Kingdom;
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Valter D. Longo
hLongevity Institute, Davis School of Gerontology and Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089;
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Willy J. Malaisse
iLaboratory of Experimental Hormonology, Brussels Free University, B-1070 Brussels, Belgium;
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Michael Mosley
jBritish Broadcasting Corporation, W1A 1AA London, United Kingdom;
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Lucia Notterpek
kDepartment of Neuroscience, College of Medicine, McKnight Brain Institute, University of Florida, Gainesville, FL 32610;
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Eric Ravussin
lPennington Biomedical Research Center, Baton Rouge, LA 70808;
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Frank A. J. L. Scheer
mHarvard Medical School and Brigham and Women’s Hospital, Boston, MA 02115;
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Thomas N. Seyfried
nBiology Department, Boston College, Chestnut Hill, MA 02467;
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Krista A. Varady
oDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL 60612; and
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Satchidananda Panda
pRegulatory Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037
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  • For correspondence: mark.mattson@nih.govpanda@salk.edu
  1. Edited by Joseph S. Takahashi, Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX, and approved October 7, 2014 (received for review July 23, 2014)

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Article Information

vol. 111 no. 47 16647-16653
DOI: 
https://doi.org/10.1073/pnas.1413965111
PubMed: 
25404320

Published By: 
National Academy of Sciences
Print ISSN: 
0027-8424
Online ISSN: 
1091-6490
History: 
  • Published in issue November 25, 2014.
  • Published first November 17, 2014.


Author Information

  1. Mark P. Mattsona,b,1,
  2. David B. Allisonc,
  3. Luigi Fontanad,e,f,
  4. Michelle Harvieg,
  5. Valter D. Longoh,
  6. Willy J. Malaissei,
  7. Michael Mosleyj,
  8. Lucia Notterpekk,
  9. Eric Ravussinl,
  10. Frank A. J. L. Scheerm,
  11. Thomas N. Seyfriedn,
  12. Krista A. Varadyo, and
  13. Satchidananda Pandap,1
  1. aLaboratory of Neurosciences, National Institute on Aging, Baltimore, MD 21224;
  2. bDepartment of Neuroscience, The Johns Hopkins University School of Medicine, Baltimore, MD 21205;
  3. cNutrition and Obesity Research Center, University of Alabama at Birmingham, Birmingham, AL 35294;
  4. dDepartment of Medicine, Washington University in St. Louis, St. Louis, MO 63130;
  5. eDepartment of Clinical and Experimental Sciences, Brescia University, 25123 Brescia, Italy;
  6. fCEINGE Biotecnologie Avanzate, 80145 Naples, Italy;
  7. gGenesis Breast Cancer Prevention Centre, University Hospital South Manchester, Wythenshaw, M23 9LT Manchester, United Kingdom;
  8. hLongevity Institute, Davis School of Gerontology and Department of Biological Sciences, University of Southern California, Los Angeles, CA 90089;
  9. iLaboratory of Experimental Hormonology, Brussels Free University, B-1070 Brussels, Belgium;
  10. jBritish Broadcasting Corporation, W1A 1AA London, United Kingdom;
  11. kDepartment of Neuroscience, College of Medicine, McKnight Brain Institute, University of Florida, Gainesville, FL 32610;
  12. lPennington Biomedical Research Center, Baton Rouge, LA 70808;
  13. mHarvard Medical School and Brigham and Women’s Hospital, Boston, MA 02115;
  14. nBiology Department, Boston College, Chestnut Hill, MA 02467;
  15. oDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL 60612; and
  16. pRegulatory Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037
  1. Edited by Joseph S. Takahashi, Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX, and approved October 7, 2014 (received for review July 23, 2014)

Footnotes

  • ↵1To whom correspondence may be addressed. Email: mark.mattson{at}nih.gov or panda{at}salk.edu.
  • Author contributions: M.P.M., D.B.A., L.F., M.H., V.D.L., W.J.M., M.M., L.N., E.R., F.A.J.L.S., T.N.S., K.A.V., and S.P. wrote the paper.

  • The authors declare no conflict of interest.

  • This article is a PNAS Direct Submission.

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Article usage

Article usage: November 2014 to February 2019

AbstractFullPdf
Nov 20141310112821771
Dec 20141114319051076
Total 20142424431872847
Jan 20158671602517
Feb 20153513343231
Mar 20152144339225
Apr 20151682380234
May 20151289278196
Jun 201511431198369
Jul 201517721476519
Aug 201513992091401
Sep 201514901352354
Oct 20151362948561
Nov 201514001009662
Dec 20151949107711231
Total 201527814207875500
Jan 201623722203779
Feb 201614671512465
Mar 201618362806622
Apr 201616221839592
May 201610061779361
Jun 20169071830269
Jul 20166641264248
Aug 201610981581248
Sep 201613111666343
Oct 201616051773672
Nov 201612402130477
Dec 201610531163329
Total 201616181215465405
Jan 201716671899456
Feb 201715881394483
Mar 201716511852588
Apr 201712681201338
May 201712131704415
Jun 20171331987408
Jul 20171430893412
Aug 20171545981393
Sep 2017999969292
Oct 201711762941443
Nov 201712191124321
Dec 2017858748474
Total 201715945166935023
Jan 201813531431370
Feb 201812271344418
Mar 201818751766401
Apr 201814371299380
May 201815431545448
Jun 201812351224398
Jul 20181269963454
Aug 201816691486332
Sep 201821091896323
Oct 20185351655402
Nov 20183061815386
Dec 20182031270245
Total 201814761176944557
Jan 20193034090538
Feb 2019186951198
Total 20194895041736
Total994348494824068
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Meal frequency and timing in health and disease
Mark P. Mattson, David B. Allison, Luigi Fontana, Michelle Harvie, Valter D. Longo, Willy J. Malaisse, Michael Mosley, Lucia Notterpek, Eric Ravussin, Frank A. J. L. Scheer, Thomas N. Seyfried, Krista A. Varady, Satchidananda Panda
Proceedings of the National Academy of Sciences Nov 2014, 111 (47) 16647-16653; DOI: 10.1073/pnas.1413965111

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Meal frequency and timing in health and disease
Mark P. Mattson, David B. Allison, Luigi Fontana, Michelle Harvie, Valter D. Longo, Willy J. Malaisse, Michael Mosley, Lucia Notterpek, Eric Ravussin, Frank A. J. L. Scheer, Thomas N. Seyfried, Krista A. Varady, Satchidananda Panda
Proceedings of the National Academy of Sciences Nov 2014, 111 (47) 16647-16653; DOI: 10.1073/pnas.1413965111
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    • Abstract
    • Evolutionary and Cultural Considerations
    • Circadian Rhythms, Meal Timing, and Health
    • Cellular and Molecular Mechanisms: Insight from Intermittent Energy Restriction and Fasting
    • Society-Wide Implications
    • Future Directions
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