Despite myriad challenges, clinicians see room for progress.
Image credit: Shutterstock/David Tadevosian.
New Research In
Physical Sciences
Featured Portals
Articles by Topic
Biological Sciences
Featured Portals
Articles by Topic
Edited by Terry L. Orr-Weaver, Whitehead Institute, Cambridge, MA, and approved November 17, 2014 (received for review October 4, 2014)
Online Impact
Article Information
PubMed:
Published By:
Print ISSN:
Online ISSN:
History:
- Published in issue December 30, 2014.
- Published first December 15, 2014.
Author Information
- Youheng Wei,
- Brad Reveal,
- John Reich,
- Willem J. Laursen1,
- Stefania Senger2,
- Tanveer Akbar,
- Takako Iida-Jones3,
- Weili Cai,
- Michal Jarnik, and
- Mary A. Lilly4
- Cell Biology and Metabolism Program, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892
Edited by Terry L. Orr-Weaver, Whitehead Institute, Cambridge, MA, and approved November 17, 2014 (received for review October 4, 2014)
Footnotes
↵1Present address: Yale Medical School, Department of Cellular and Molecular Physiology, New Haven, CT 06510.
↵2Present address: Mucosal Immunology and Biology Research Center, Massachusetts General Hospital for Children and Harvard Medical School, Boston, MA 024114.
↵3Present address: Wellstone Program, Department of Cell and Developmental Biology, University of Massachusetts Medical School, Worcester, MA 01655.
- ↵4To whom correspondence should be addressed. Email: mlilly{at}helix.nih.gov.
Author contributions: Y.W., B.R., J.R., W.J.L., S.S., T.A., T.I.-J., W.C., and M.A.L. designed research; Y.W., B.R., J.R., W.J.L., T.A., W.C., and M.J. performed research; B.R., S.S., T.A., and T.I.-J. contributed new reagents/analytic tools; Y.W., B.R., J.R., W.J.L., T.A., W.C., M.J., and M.A.L. analyzed data; and Y.W. and M.A.L. wrote the paper.
The authors declare no conflict of interest.
This article is a PNAS Direct Submission.
This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1419156112/-/DCSupplemental.
Cited By...
Article usage
Iml1/GATOR1 controls meiotic entry in Drosophila
Sign up for Article Alerts
Article Classifications
- Biological Sciences
- Genetics
Jump to section
You May Also be Interested in
Better explicating the strengths and shortcomings of these models will help refine projections and improve transparency in the years ahead.
Image credit: Witsawat.S.
Using CRISPR, researchers showed that a region some used to label “junk DNA” has a major role in a rare genetic disorder.
Image credit: Nathan Devery.
Mara Reed and Michael Manga explore why Yellowstone's Steamboat Geyser resumed erupting in 2018.
A study demonstrates how two enzymes—MHETase and PETase—work synergistically to depolymerize the plastic pollutant PET.
Image credit: Aaron McGeehan (artist).