Skip to main content

Main menu

  • Home
  • Articles
    • Current
    • Special Feature Articles - Most Recent
    • Special Features
    • Colloquia
    • Collected Articles
    • PNAS Classics
    • List of Issues
  • Front Matter
    • Front Matter Portal
    • Journal Club
  • News
    • For the Press
    • This Week In PNAS
    • PNAS in the News
  • Podcasts
  • Authors
    • Information for Authors
    • Editorial and Journal Policies
    • Submission Procedures
    • Fees and Licenses
  • Submit
  • Submit
  • About
    • Editorial Board
    • PNAS Staff
    • FAQ
    • Accessibility Statement
    • Rights and Permissions
    • Site Map
  • Contact
  • Journal Club
  • Subscribe
    • Subscription Rates
    • Subscriptions FAQ
    • Open Access
    • Recommend PNAS to Your Librarian

User menu

  • Log in
  • My Cart

Search

  • Advanced search
Home
Home
  • Log in
  • My Cart

Advanced Search

  • Home
  • Articles
    • Current
    • Special Feature Articles - Most Recent
    • Special Features
    • Colloquia
    • Collected Articles
    • PNAS Classics
    • List of Issues
  • Front Matter
    • Front Matter Portal
    • Journal Club
  • News
    • For the Press
    • This Week In PNAS
    • PNAS in the News
  • Podcasts
  • Authors
    • Information for Authors
    • Editorial and Journal Policies
    • Submission Procedures
    • Fees and Licenses
  • Submit

New Research In

Physical Sciences

Featured Portals

  • Physics
  • Chemistry
  • Sustainability Science

Articles by Topic

  • Applied Mathematics
  • Applied Physical Sciences
  • Astronomy
  • Computer Sciences
  • Earth, Atmospheric, and Planetary Sciences
  • Engineering
  • Environmental Sciences
  • Mathematics
  • Statistics

Social Sciences

Featured Portals

  • Anthropology
  • Sustainability Science

Articles by Topic

  • Economic Sciences
  • Environmental Sciences
  • Political Sciences
  • Psychological and Cognitive Sciences
  • Social Sciences

Biological Sciences

Featured Portals

  • Sustainability Science

Articles by Topic

  • Agricultural Sciences
  • Anthropology
  • Applied Biological Sciences
  • Biochemistry
  • Biophysics and Computational Biology
  • Cell Biology
  • Developmental Biology
  • Ecology
  • Environmental Sciences
  • Evolution
  • Genetics
  • Immunology and Inflammation
  • Medical Sciences
  • Microbiology
  • Neuroscience
  • Pharmacology
  • Physiology
  • Plant Biology
  • Population Biology
  • Psychological and Cognitive Sciences
  • Sustainability Science
  • Systems Biology

Table of Contents

March 17, 2015; vol. 112 no. 11

This Week in PNAS

  • You have access
    In This Issue
    PNAS March 17, 2015 112 (11) 3171-3172; https://doi.org/10.1073/iti1115112

PNAS 100th Anniversary Article

  • Commentary

    • You have access
      Hubble’s Law and the expanding universe
      Neta A. Bahcall
      PNAS March 17, 2015 112 (11) 3173-3175; https://doi.org/10.1073/pnas.1424299112

      See companion article:

      • Hubble's quarter century in orbit
        - Mar 17, 2015
      • A relation between distance and radial velocity among extra-galactic nebulae
        - Mar 15, 1929

Letters (Online Only)

  • You have access
    Big changes before big birthdays? Panel data provide no evidence of end-of-decade crises
    Simon Kühne, Thorsten Schneider, and David Richter
    PNAS March 17, 2015 112 (11) E1170; first published February 18, 2015. https://doi.org/10.1073/pnas.1424903112
  • You have access
    Reply to Kühne et al.: Still good evidence that people search for meaning when they approach a new decade in chronological age
    Adam L. Alter and Hal E. Hershfield
    PNAS March 17, 2015 112 (11) E1171; first published February 18, 2015. https://doi.org/10.1073/pnas.1500787112

    See companion article:

    • New decades in age and the search for meaning
      - Nov 17, 2014
  • You have access
    Titin ruler hypothesis not refuted
    Larissa Tskhovrebova, Pauline Bennett, Mathias Gautel, and John Trinick
    PNAS March 17, 2015 112 (11) E1172; first published February 18, 2015. https://doi.org/10.1073/pnas.1422326112
  • You have access
    Reply to Tskhovrebova et al.: Titin’s IA junction does not control thick filament length
    Henk L. Granzier
    PNAS March 17, 2015 112 (11) E1173; first published February 18, 2015. https://doi.org/10.1073/pnas.1500871112

    See companion article:

    • Titin's role in muscle structure and function
      - Sep 22, 2014

Inner Workings

An over-the-shoulder look at scientists at work.
  • You have access
    Inner Workings: Hubble’s quarter century in orbit has opened a universe of possibilities
    • Front Matter
    David J. Harris
    PNAS March 17, 2015 112 (11) 3176-3177; https://doi.org/10.1073/pnas.1500872112

    See companion article:

    • Hubble's Law and the expanding universe
      - Mar 17, 2015

Commentaries

  • You have access
    Circulating tumor-derived DNA is shorter than somatic DNA in plasma
    Florent Mouliere and Nitzan Rosenfeld
    PNAS March 17, 2015 112 (11) 3178-3179; first published March 2, 2015. https://doi.org/10.1073/pnas.1501321112

    See companion article:

    • Lengthening and shortening of plasma DNA in cancer
      - Feb 02, 2015
  • You have access
    Mitochondrial metabolism is regulated by thioredoxin
    Ian Max Møller
    PNAS March 17, 2015 112 (11) 3180-3181; first published March 9, 2015. https://doi.org/10.1073/pnas.1502425112

    See companion article:

    • Thioredoxin-mediated TCA cycle regulation
      - Feb 02, 2015
  • You have access
    Stimulating minds to wander
    James M. Broadway, Claire M. Zedelius, Benjamin W. Mooneyham, Michael D. Mrazek, and Jonathan W. Schooler
    PNAS March 17, 2015 112 (11) 3182-3183; first published March 9, 2015. https://doi.org/10.1073/pnas.1503093112

    See companion article:

    • Increasing propensity to mind-wander with tDCS
      - Feb 17, 2015
  • You have access
    Cortical computation in mammals and birds
    Kenneth D. Harris
    PNAS March 17, 2015 112 (11) 3184-3185; first published March 9, 2015. https://doi.org/10.1073/pnas.1502209112

    See companion article:

    • Neocortical microcircuit in the avian brain
      - Feb 17, 2015

PNAS Plus Significance Statements

Brief statements written by the authors about the significance of their papers.
  • You have access
    PNAS Plus Significance Statements
    PNAS March 17, 2015 112 (11) 3186-3190; https://doi.org/10.1073/pnas.ss11211

Physical Sciences

  • Applied Physical Sciences

    • Open Access
      Polytypism, polymorphism, and superconductivity in TaSe2−xTex
      Huixia Luo, Weiwei Xie, Jing Tao, Hiroyuki Inoue, András Gyenis, Jason W. Krizan, Ali Yazdani, Yimei Zhu, and Robert Joseph Cava
      PNAS March 17, 2015 112 (11) E1174-E1180; first published March 3, 2015. https://doi.org/10.1073/pnas.1502460112
    • Open Access
      Nucleation of metastable aragonite CaCO3 in seawater
      Wenhao Sun, Saivenkataraman Jayaraman, Wei Chen, Kristin A. Persson, and Gerbrand Ceder
      PNAS March 17, 2015 112 (11) 3199-3204; first published March 4, 2015. https://doi.org/10.1073/pnas.1423898112
  • Chemistry

    • Open Access
      De novo production of the plant-derived alkaloid strictosidine in yeast
      Stephanie Brown, Marc Clastre, Vincent Courdavault, and Sarah E. O’Connor
      PNAS March 17, 2015 112 (11) 3205-3210; first published February 9, 2015. https://doi.org/10.1073/pnas.1423555112
    • You have access
      Glutathione and multidrug resistance protein transporter mediate a self-propelled disposal of bismuth in human cells
      Yifan Hong, Yau-Tsz Lai, Godfrey Chi-Fung Chan, and Hongzhe Sun
      PNAS March 17, 2015 112 (11) 3211-3216; first published March 3, 2015. https://doi.org/10.1073/pnas.1421002112

      See companion article:

      • Systems pharmacology for metallodrugs
        - Mar 30, 2015
    • You have access
      Spray-combustion synthesis: Efficient solution route to high-performance oxide transistors
      • From the Cover
      Xinge Yu, Jeremy Smith, Nanjia Zhou, Li Zeng, Peijun Guo, Yu Xia, Ana Alvarez, Stefano Aghion, Hui Lin, Junsheng Yu, Robert P. H. Chang, Michael J. Bedzyk, Rafael Ferragut, Tobin J. Marks, and Antonio Facchetti
      PNAS March 17, 2015 112 (11) 3217-3222; first published March 2, 2015. https://doi.org/10.1073/pnas.1501548112
    • You have access
      Structure of superhard tungsten tetraboride: A missing link between MB2 and MB12 higher borides
      Andrew T. Lech, Christopher L. Turner, Reza Mohammadi, Sarah H. Tolbert, and Richard B. Kaner
      PNAS March 17, 2015 112 (11) 3223-3228; first published March 2, 2015. https://doi.org/10.1073/pnas.1415018112
    • You have access
      Two-dimensional IR spectroscopy of the anti-HIV agent KP1212 reveals protonated and neutral tautomers that influence pH-dependent mutagenicity
      Chunte Sam Peng, Bogdan I. Fedeles, Vipender Singh, Deyu Li, Tiffany Amariuta, John M. Essigmann, and Andrei Tokmakoff
      PNAS March 17, 2015 112 (11) 3229-3234; first published March 2, 2015. https://doi.org/10.1073/pnas.1415974112
    • You have access
      Locating landmarks on high-dimensional free energy surfaces
      Ming Chen, Tang-Qing Yu, and Mark E. Tuckerman
      PNAS March 17, 2015 112 (11) 3235-3240; first published March 3, 2015. https://doi.org/10.1073/pnas.1418241112
  • Earth, Atmospheric, and Planetary Sciences

    • You have access
      Climate change in the Fertile Crescent and implications of the recent Syrian drought
      Colin P. Kelley, Shahrzad Mohtadi, Mark A. Cane, Richard Seager, and Yochanan Kushnir
      PNAS March 17, 2015 112 (11) 3241-3246; first published March 2, 2015. https://doi.org/10.1073/pnas.1421533112
    • Open Access
      Vapor hydrogen and oxygen isotopes reflect water of combustion in the urban atmosphere
      Galen Gorski, Courtenay Strong, Stephen P. Good, Ryan Bares, James R. Ehleringer, and Gabriel J. Bowen
      PNAS March 17, 2015 112 (11) 3247-3252; first published March 2, 2015. https://doi.org/10.1073/pnas.1424728112
    • Open Access
      Dynamical evidence for causality between galactic cosmic rays and interannual variation in global temperature
      Anastasios A. Tsonis, Ethan R. Deyle, Robert M. May, George Sugihara, Kyle Swanson, Joshua D. Verbeten, and Geli Wang
      PNAS March 17, 2015 112 (11) 3253-3256; first published March 2, 2015. https://doi.org/10.1073/pnas.1420291112

      See companion article:

      • Causal effects of cosmic rays on temperature
        - Aug 17, 2015
    • Open Access
      Effects of large-scale deforestation on precipitation in the monsoon regions: Remote versus local effects
      N. Devaraju, Govindasamy Bala, and Angshuman Modak
      PNAS March 17, 2015 112 (11) 3257-3262; first published March 2, 2015. https://doi.org/10.1073/pnas.1423439112
    • Open Access
      Ocean-driven thinning enhances iceberg calving and retreat of Antarctic ice shelves
      Yan Liu, John C. Moore, Xiao Cheng, Rupert M. Gladstone, Jeremy N. Bassis, Hongxing Liu, Jiahong Wen, and Fengming Hui
      PNAS March 17, 2015 112 (11) 3263-3268; first published March 2, 2015. https://doi.org/10.1073/pnas.1415137112
  • Engineering

    • You have access
      Implantable hydrogel embedded dark-gold nanoswitch as a theranostic probe to sense and overcome cancer multidrug resistance
      João Conde, Nuria Oliva, and Natalie Artzi
      PNAS March 17, 2015 112 (11) E1278-E1287; first published March 2, 2015. https://doi.org/10.1073/pnas.1421229112
    • You have access
      Quorum-sensing Salmonella selectively trigger protein expression within tumors
      Charles A. Swofford, Nele Van Dessel, and Neil S. Forbes
      PNAS March 17, 2015 112 (11) 3457-3462; first published March 3, 2015. https://doi.org/10.1073/pnas.1414558112
  • Physics

    • You have access
      n-type thermoelectric material Mg2Sn0.75Ge0.25 for high power generation
      Weishu Liu, Hee Seok Kim, Shuo Chen, Qing Jie, Bing Lv, Mengliang Yao, Zhensong Ren, Cyril P. Opeil, Stephen Wilson, Ching-Wu Chu, and Zhifeng Ren
      PNAS March 17, 2015 112 (11) 3269-3274; first published March 2, 2015. https://doi.org/10.1073/pnas.1424388112
    • You have access
      The second laws of quantum thermodynamics
      Fernando Brandão, Michał Horodecki, Nelly Ng, Jonathan Oppenheim, and Stephanie Wehner
      PNAS March 17, 2015 112 (11) 3275-3279; first published February 9, 2015. https://doi.org/10.1073/pnas.1411728112
    • You have access
      Kelvin–Helmholtz instability in an ultrathin air film causes drop splashing on smooth surfaces
      Yuan Liu, Peng Tan, and Lei Xu
      PNAS March 17, 2015 112 (11) 3280-3284; first published February 23, 2015. https://doi.org/10.1073/pnas.1417718112
    • You have access
      Avoided valence transition in a plutonium superconductor
      B. J. Ramshaw, Arkady Shekhter, Ross D. McDonald, Jon B. Betts, J. N. Mitchell, P. H. Tobash, C. H. Mielke, E. D. Bauer, and Albert Migliori
      PNAS March 17, 2015 112 (11) 3285-3289; first published March 3, 2015. https://doi.org/10.1073/pnas.1421174112
    • Open Access
      Dynamical phase transition in the open Dicke model
      Jens Klinder, Hans Keßler, Matthias Wolke, Ludwig Mathey, and Andreas Hemmerich
      PNAS March 17, 2015 112 (11) 3290-3295; first published March 2, 2015. https://doi.org/10.1073/pnas.1417132112

Social Sciences

  • Anthropology

    • You have access
      Core questions in domestication research
      • Inaugural Article
      Melinda A. Zeder
      PNAS March 17, 2015 112 (11) 3191-3198; first published February 20, 2015. https://doi.org/10.1073/pnas.1501711112

      See companion article:

      • Profile of Melinda A. Zeder
        - Apr 06, 2015

      See companion article:

      • Human behavioral ecology needs a rethink
        - Jun 01, 2015
    • You have access
      Impacts of biological globalization in the Mediterranean: Unveiling the deep history of human-mediated gamebird dispersal
      Giovanni Forcina, Monica Guerrini, Hein van Grouw, Brij K. Gupta, Panicos Panayides, Pantelis Hadjigerou, Omar F. Al-Sheikhly, Muhammad N. Awan, Aleem A. Khan, Melinda A. Zeder, and Filippo Barbanera
      PNAS March 17, 2015 112 (11) 3296-3301; first published March 2, 2015. https://doi.org/10.1073/pnas.1500677112
    • You have access
      Evidence for recent, population-specific evolution of the human mutation rate
      Kelley Harris
      PNAS March 17, 2015 112 (11) 3439-3444; first published March 2, 2015. https://doi.org/10.1073/pnas.1418652112
  • Environmental Sciences

    • You have access
      Climate change in the Fertile Crescent and implications of the recent Syrian drought
      Colin P. Kelley, Shahrzad Mohtadi, Mark A. Cane, Richard Seager, and Yochanan Kushnir
      PNAS March 17, 2015 112 (11) 3241-3246; first published March 2, 2015. https://doi.org/10.1073/pnas.1421533112
    • Open Access
      Vapor hydrogen and oxygen isotopes reflect water of combustion in the urban atmosphere
      Galen Gorski, Courtenay Strong, Stephen P. Good, Ryan Bares, James R. Ehleringer, and Gabriel J. Bowen
      PNAS March 17, 2015 112 (11) 3247-3252; first published March 2, 2015. https://doi.org/10.1073/pnas.1424728112
  • Political Sciences

    • You have access
      Prepregnancy body mass and weight gain during pregnancy in India and sub-Saharan Africa
      Diane Coffey
      PNAS March 17, 2015 112 (11) 3302-3307; first published March 2, 2015. https://doi.org/10.1073/pnas.1416964112
  • Psychological and Cognitive Sciences

    • You have access
      Disruption of hierarchical predictive coding during sleep
      Melanie Strauss, Jacobo D. Sitt, Jean-Remi King, Maxime Elbaz, Leila Azizi, Marco Buiatti, Lionel Naccache, Virginie van Wassenhove, and Stanislas Dehaene
      PNAS March 17, 2015 112 (11) E1353-E1362; first published March 3, 2015. https://doi.org/10.1073/pnas.1501026112
    • Open Access
      Epigenetic modification of the oxytocin receptor gene influences the perception of anger and fear in the human brain
      Meghan H. Puglia, Travis S. Lillard, James P. Morris, and Jessica J. Connelly
      PNAS March 17, 2015 112 (11) 3308-3313; first published February 9, 2015. https://doi.org/10.1073/pnas.1422096112
    • You have access
      Increasing propensity to mind-wander with transcranial direct current stimulation
      • From the Cover
      Vadim Axelrod, Geraint Rees, Michal Lavidor, and Moshe Bar
      PNAS March 17, 2015 112 (11) 3314-3319; first published February 17, 2015. https://doi.org/10.1073/pnas.1421435112

      See companion article:

      • Stimulating minds to wander
        - Mar 09, 2015

Biological Sciences

  • Applied Biological Sciences

    • You have access
      Antigen specificity can be irrelevant to immunocytokine efficacy and biodistribution
      Alice Tzeng, Byron H. Kwan, Cary F. Opel, Tejas Navaratna, and K. Dane Wittrup
      PNAS March 17, 2015 112 (11) 3320-3325; first published March 2, 2015. https://doi.org/10.1073/pnas.1416159112
  • Biochemistry

    • You have access
      Comprehensive analysis of heterotrimeric G-protein complex diversity and their interactions with GPCRs in solution
      Matthias Hillenbrand, Christian Schori, Jendrik Schöppe, and Andreas Plückthun
      PNAS March 17, 2015 112 (11) E1181-E1190; first published March 2, 2015. https://doi.org/10.1073/pnas.1417573112
    • You have access
      Dramatically reduced spliceosome in Cyanidioschyzon merolae
      Martha R. Stark, Elizabeth A. Dunn, William S. C. Dunn, Cameron J. Grisdale, Anthony R. Daniele, Matthew R. G. Halstead, Naomi M. Fast, and Stephen D. Rader
      PNAS March 17, 2015 112 (11) E1191-E1200; first published March 2, 2015. https://doi.org/10.1073/pnas.1416879112
    • Open Access
      Myosin VI deafness mutation prevents the initiation of processive runs on actin
      Olena Pylypenko, Lin Song, Ai Shima, Zhaohui Yang, Anne M. Houdusse, and H. Lee Sweeney
      PNAS March 17, 2015 112 (11) E1201-E1209; first published March 6, 2015. https://doi.org/10.1073/pnas.1420989112
    • Open Access
      De novo production of the plant-derived alkaloid strictosidine in yeast
      Stephanie Brown, Marc Clastre, Vincent Courdavault, and Sarah E. O’Connor
      PNAS March 17, 2015 112 (11) 3205-3210; first published February 9, 2015. https://doi.org/10.1073/pnas.1423555112
    • You have access
      Steric clashes with bound OMP peptides activate the DegS stress-response protease
      Anna K. de Regt, Tania A. Baker, and Robert T. Sauer
      PNAS March 17, 2015 112 (11) 3326-3331; first published March 2, 2015. https://doi.org/10.1073/pnas.1502372112
    • You have access
      Functional analysis of (4S)-limonene synthase mutants reveals determinants of catalytic outcome in a model monoterpene synthase
      Narayanan Srividya, Edward M. Davis, Rodney B. Croteau, and B. Markus Lange
      PNAS March 17, 2015 112 (11) 3332-3337; first published March 2, 2015. https://doi.org/10.1073/pnas.1501203112
    • You have access
      Rationally designed fluorogenic protease reporter visualizes spatiotemporal dynamics of apoptosis in vivo
      Tsz-Leung To, Beverly J. Piggott, Kalpana Makhijani, Dan Yu, Yuh Nung Jan, and Xiaokun Shu
      PNAS March 17, 2015 112 (11) 3338-3343; first published March 2, 2015. https://doi.org/10.1073/pnas.1502857112
    • Open Access
      Cleavage of amyloid precursor protein by an archaeal presenilin homologue PSH
      Shangyu Dang, Shenjie Wu, Jiawei Wang, Hongbo Li, Min Huang, Wei He, Yue-Ming Li, Catherine C. L. Wong, and Yigong Shi
      PNAS March 17, 2015 112 (11) 3344-3349; first published March 2, 2015. https://doi.org/10.1073/pnas.1502150112
    • You have access
      Atg13 HORMA domain recruits Atg9 vesicles during autophagosome formation
      Sho W. Suzuki, Hayashi Yamamoto, Yu Oikawa, Chika Kondo-Kakuta, Yayoi Kimura, Hisashi Hirano, and Yoshinori Ohsumi
      PNAS March 17, 2015 112 (11) 3350-3355; first published March 3, 2015. https://doi.org/10.1073/pnas.1421092112
    • Open Access
      Plasmodium falciparum chloroquine resistance transporter is a H+-coupled polyspecific nutrient and drug exporter
      Narinobu Juge, Sawako Moriyama, Takaaki Miyaji, Mamiyo Kawakami, Haruka Iwai, Tomoya Fukui, Nathan Nelson, Hiroshi Omote, and Yoshinori Moriyama
      PNAS March 17, 2015 112 (11) 3356-3361; first published March 2, 2015. https://doi.org/10.1073/pnas.1417102112
  • Biophysics and Computational Biology

    • Open Access
      Salient features of otoacoustic emissions are common across tetrapod groups and suggest shared properties of generation mechanisms
      Christopher Bergevin, Geoffrey A. Manley, and Christine Köppl
      PNAS March 17, 2015 112 (11) 3362-3367; first published March 3, 2015. https://doi.org/10.1073/pnas.1418569112
    • You have access
      Electron crystallography of ultrathin 3D protein crystals: Atomic model with charges
      Koji Yonekura, Kazuyuki Kato, Mitsuo Ogasawara, Masahiro Tomita, and Chikashi Toyoshima
      PNAS March 17, 2015 112 (11) 3368-3373; first published February 17, 2015. https://doi.org/10.1073/pnas.1500724112
    • You have access
      Conformation and dynamics of the Gag polyprotein of the human immunodeficiency virus 1 studied by NMR spectroscopy
      Lalit Deshmukh, Rodolfo Ghirlando, and G. Marius Clore
      PNAS March 17, 2015 112 (11) 3374-3379; first published February 23, 2015. https://doi.org/10.1073/pnas.1501985112
    • You have access
      Nanomechanics and intermolecular forces of amyloid revealed by four-dimensional electron microscopy
      Anthony W. P. Fitzpatrick, Giovanni M. Vanacore, and Ahmed H. Zewail
      PNAS March 17, 2015 112 (11) 3380-3385; first published March 2, 2015. https://doi.org/10.1073/pnas.1502214112
    • You have access
      L596–W733 bond between the start of the S4–S5 linker and the TRP box stabilizes the closed state of TRPV4 channel
      Jinfeng Teng, Stephen H. Loukin, Andriy Anishkin, and Ching Kung
      PNAS March 17, 2015 112 (11) 3386-3391; first published March 3, 2015. https://doi.org/10.1073/pnas.1502366112
    • You have access
      Pigeons trade efficiency for stability in response to level of challenge during confined flight
      C. David Williams and Andrew A. Biewener
      PNAS March 17, 2015 112 (11) 3392-3396; first published March 2, 2015. https://doi.org/10.1073/pnas.1407298112
    • You have access
      Mutation of a single residue in the ba3 oxidase specifically impairs protonation of the pump site
      Christoph von Ballmoos, Nathalie Gonska, Peter Lachmann, Robert B. Gennis, Pia Ädelroth, and Peter Brzezinski
      PNAS March 17, 2015 112 (11) 3397-3402; first published March 2, 2015. https://doi.org/10.1073/pnas.1422434112
    • You have access
      Cation-induced kinetic heterogeneity of the intron–exon recognition in single group II introns
      Danny Kowerko, Sebastian L. B. König, Miriam Skilandat, Daniela Kruschel, Mélodie C. A. S. Hadzic, Lucia Cardo, and Roland K. O. Sigel
      PNAS March 17, 2015 112 (11) 3403-3408; first published March 3, 2015. https://doi.org/10.1073/pnas.1322759112
    • You have access
      Structure and dynamics of the MKK7–JNK signaling complex
      Jaka Kragelj, Andrés Palencia, Max H. Nanao, Damien Maurin, Guillaume Bouvignies, Martin Blackledge, and Malene Ringkjøbing Jensen
      PNAS March 17, 2015 112 (11) 3409-3414; first published March 3, 2015. https://doi.org/10.1073/pnas.1419528112
  • Cell Biology

    • You have access
      BRUCE regulates DNA double-strand break response by promoting USP8 deubiquitination of BRIT1
      Chunmin Ge, Lixiao Che, Jinyu Ren, Raj K. Pandita, Jing Lu, Kaiyi Li, Tej K. Pandita, and Chunying Du
      PNAS March 17, 2015 112 (11) E1210-E1219; first published March 2, 2015. https://doi.org/10.1073/pnas.1418335112
    • Open Access
      Proteome-wide analysis of mutant p53 targets in breast cancer identifies new levels of gain-of-function that influence PARP, PCNA, and MCM4
      Alla Polotskaia, Gu Xiao, Katherine Reynoso, Che Martin, Wei-Gang Qiu, Ronald C. Hendrickson, and Jill Bargonetti
      PNAS March 17, 2015 112 (11) E1220-E1229; first published March 2, 2015. https://doi.org/10.1073/pnas.1416318112
    • You have access
      Endocannabinoids are conserved inhibitors of the Hedgehog pathway
      Helena Khaliullina, Mesut Bilgin, Julio L. Sampaio, Andrej Shevchenko, and Suzanne Eaton
      PNAS March 17, 2015 112 (11) 3415-3420; first published March 2, 2015. https://doi.org/10.1073/pnas.1416463112
    • You have access
      Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression
      Kristen M. Turner, Youting Sun, Ping Ji, Kirsi J. Granberg, Brady Bernard, Limei Hu, David E. Cogdell, Xinhui Zhou, Olli Yli-Harja, Matti Nykter, Ilya Shmulevich, W. K. Alfred Yung, Gregory N. Fuller, and Wei Zhang
      PNAS March 17, 2015 112 (11) 3421-3426; first published March 3, 2015. https://doi.org/10.1073/pnas.1414573112
  • Ecology

    • Open Access
      Hadal biosphere: Insight into the microbial ecosystem in the deepest ocean on Earth
      Takuro Nunoura, Yoshihiro Takaki, Miho Hirai, Shigeru Shimamura, Akiko Makabe, Osamu Koide, Tohru Kikuchi, Junichi Miyazaki, Keisuke Koba, Naohiro Yoshida, Michinari Sunamura, and Ken Takai
      PNAS March 17, 2015 112 (11) E1230-E1236; first published February 23, 2015. https://doi.org/10.1073/pnas.1421816112
    • You have access
      Rapid behavioral maturation accelerates failure of stressed honey bee colonies
      • From the Cover
      Clint J. Perry, Eirik Søvik, Mary R. Myerscough, and Andrew B. Barron
      PNAS March 17, 2015 112 (11) 3427-3432; first published February 9, 2015. https://doi.org/10.1073/pnas.1422089112
    • Open Access
      Pollinator recognition by a keystone tropical plant
      Matthew G. Betts, Adam S. Hadley, and W. John Kress
      PNAS March 17, 2015 112 (11) 3433-3438; first published March 2, 2015. https://doi.org/10.1073/pnas.1419522112
  • Environmental Sciences

    • Open Access
      Climate change and pollution speed declines in zebrafish populations
      A. Ross Brown, Stewart F. Owen, James Peters, Yong Zhang, Marta Soffker, Gregory C. Paull, David J. Hosken, M. Abdul Wahab, and Charles R. Tyler
      PNAS March 17, 2015 112 (11) E1237-E1246; first published March 2, 2015. https://doi.org/10.1073/pnas.1416269112
  • Evolution

    • Open Access
      Extraordinary diversity of visual opsin genes in dragonflies
      • From the Cover
      Ryo Futahashi, Ryouka Kawahara-Miki, Michiyo Kinoshita, Kazutoshi Yoshitake, Shunsuke Yajima, Kentaro Arikawa, and Takema Fukatsu
      PNAS March 17, 2015 112 (11) E1247-E1256; first published February 23, 2015. https://doi.org/10.1073/pnas.1424670112
    • You have access
      Whole-genome sequence of the Tibetan frog Nanorana parkeri and the comparative evolution of tetrapod genomes
      Yan-Bo Sun, Zi-Jun Xiong, Xue-Yan Xiang, Shi-Ping Liu, Wei-Wei Zhou, Xiao-Long Tu, Li Zhong, Lu Wang, Dong-Dong Wu, Bao-Lin Zhang, Chun-Ling Zhu, Min-Min Yang, Hong-Man Chen, Fang Li, Long Zhou, Shao-Hong Feng, Chao Huang, Guo-Jie Zhang, David Irwin, David M. Hillis, Robert W. Murphy, Huan-Ming Yang, Jing Che, Jun Wang, and Ya-Ping Zhang
      PNAS March 17, 2015 112 (11) E1257-E1262; first published March 2, 2015. https://doi.org/10.1073/pnas.1501764112
    • You have access
      Core questions in domestication research
      • Inaugural Article
      Melinda A. Zeder
      PNAS March 17, 2015 112 (11) 3191-3198; first published February 20, 2015. https://doi.org/10.1073/pnas.1501711112

      See companion article:

      • Profile of Melinda A. Zeder
        - Apr 06, 2015

      See companion article:

      • Human behavioral ecology needs a rethink
        - Jun 01, 2015
    • You have access
      Evidence for recent, population-specific evolution of the human mutation rate
      Kelley Harris
      PNAS March 17, 2015 112 (11) 3439-3444; first published March 2, 2015. https://doi.org/10.1073/pnas.1418652112
  • Genetics

    • Open Access
      Sequential de novo centromere formation and inactivation on a chromosomal fragment in maize
      Yalin Liu, Handong Su, Junling Pang, Zhi Gao, Xiu-Jie Wang, James A. Birchler, and Fangpu Han
      PNAS March 17, 2015 112 (11) E1263-E1271; first published March 2, 2015. https://doi.org/10.1073/pnas.1418248112
    • You have access
      Recurrent BCAM-AKT2 fusion gene leads to a constitutively activated AKT2 fusion kinase in high-grade serous ovarian carcinoma
      Kalpana Kannan, Cristian Coarfa, Pei-Wen Chao, Liming Luo, Yan Wang, Amy E. Brinegar, Shannon M. Hawkins, Aleksandar Milosavljevic, Martin M. Matzuk, and Laising Yen
      PNAS March 17, 2015 112 (11) E1272-E1277; first published March 2, 2015. https://doi.org/10.1073/pnas.1501735112
    • You have access
      Impacts of biological globalization in the Mediterranean: Unveiling the deep history of human-mediated gamebird dispersal
      Giovanni Forcina, Monica Guerrini, Hein van Grouw, Brij K. Gupta, Panicos Panayides, Pantelis Hadjigerou, Omar F. Al-Sheikhly, Muhammad N. Awan, Aleem A. Khan, Melinda A. Zeder, and Filippo Barbanera
      PNAS March 17, 2015 112 (11) 3296-3301; first published March 2, 2015. https://doi.org/10.1073/pnas.1500677112
    • Open Access
      Epigenetic modification of the oxytocin receptor gene influences the perception of anger and fear in the human brain
      Meghan H. Puglia, Travis S. Lillard, James P. Morris, and Jessica J. Connelly
      PNAS March 17, 2015 112 (11) 3308-3313; first published February 9, 2015. https://doi.org/10.1073/pnas.1422096112
    • You have access
      Systematic discovery of regulated and conserved alternative exons in the mammalian brain reveals NMD modulating chromatin regulators
      Qinghong Yan, Sebastien M. Weyn-Vanhentenryck, Jie Wu, Steven A. Sloan, Ye Zhang, Kenian Chen, Jia Qian Wu, Ben A. Barres, and Chaolin Zhang
      PNAS March 17, 2015 112 (11) 3445-3450; first published March 3, 2015. https://doi.org/10.1073/pnas.1502849112
    • You have access
      Horizontal gene transfer and gene dosage drives adaptation to wood colonization in a tree pathogen
      Braham Dhillon, Nicolas Feau, Andrea L. Aerts, Stéphanie Beauseigle, Louis Bernier, Alex Copeland, Adam Foster, Navdeep Gill, Bernard Henrissat, Padmini Herath, Kurt M. LaButti, Anthony Levasseur, Erika A. Lindquist, Eline Majoor, Robin A. Ohm, Jasmyn L. Pangilinan, Amadeus Pribowo, John N. Saddler, Monique L. Sakalidis, Ronald P. de Vries, Igor V. Grigoriev, Stephen B. Goodwin, Philippe Tanguay, and Richard C. Hamelin
      PNAS March 17, 2015 112 (11) 3451-3456; first published March 2, 2015. https://doi.org/10.1073/pnas.1424293112
  • Medical Sciences

    • You have access
      Implantable hydrogel embedded dark-gold nanoswitch as a theranostic probe to sense and overcome cancer multidrug resistance
      João Conde, Nuria Oliva, and Natalie Artzi
      PNAS March 17, 2015 112 (11) E1278-E1287; first published March 2, 2015. https://doi.org/10.1073/pnas.1421229112
    • You have access
      Assessment of ABT-263 activity across a cancer cell line collection leads to a potent combination therapy for small-cell lung cancer
      Anthony C. Faber, Anna F. Farago, Carlotta Costa, Anahita Dastur, Maria Gomez-Caraballo, Rebecca Robbins, Bethany L. Wagner, William M. Rideout III, Charles T. Jakubik, Jungoh Ham, Elena J. Edelman, Hiromichi Ebi, Alan T. Yeo, Aaron N. Hata, Youngchul Song, Neha U. Patel, Ryan J. March, Ah Ting Tam, Randy J. Milano, Jessica L. Boisvert, Mark A. Hicks, Sarah Elmiligy, Scott E. Malstrom, Miguel N. Rivera, Hisashi Harada, Brad E. Windle, Sridhar Ramaswamy, Cyril H. Benes, Tyler Jacks, and Jeffrey A. Engelman
      PNAS March 17, 2015 112 (11) E1288-E1296; first published March 3, 2015. https://doi.org/10.1073/pnas.1411848112
    • Open Access
      Controlled tetra-Fc sialylation of IVIg results in a drug candidate with consistent enhanced anti-inflammatory activity
      Nathaniel Washburn, Inessa Schwab, Daniel Ortiz, Naveen Bhatnagar, Jonathan C. Lansing, Amy Medeiros, Steven Tyler, Divya Mekala, Edward Cochran, Hetal Sarvaiya, Kevin Garofalo, Robin Meccariello, James W. Meador III, Laura Rutitzky, Birgit C. Schultes, Leona Ling, William Avery, Falk Nimmerjahn, Anthony M. Manning, Ganesh V. Kaundinya, and Carlos J. Bosques
      PNAS March 17, 2015 112 (11) E1297-E1306; first published March 2, 2015. https://doi.org/10.1073/pnas.1422481112
    • You have access
      Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing
      Saravana P. Selvanathan, Garrett T. Graham, Hayriye V. Erkizan, Uta Dirksen, Thanemozhi G. Natarajan, Aleksandra Dakic, Songtao Yu, Xuefeng Liu, Michelle T. Paulsen, Mats E. Ljungman, Cathy H. Wu, Elizabeth R. Lawlor, Aykut Üren, and Jeffrey A. Toretsky
      PNAS March 17, 2015 112 (11) E1307-E1316; first published March 3, 2015. https://doi.org/10.1073/pnas.1500536112
    • Open Access
      Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients
      Peiyong Jiang, Carol W. M. Chan, K. C. Allen Chan, Suk Hang Cheng, John Wong, Vincent Wai-Sun Wong, Grace L. H. Wong, Stephen L. Chan, Tony S. K. Mok, Henry L. Y. Chan, Paul B. S. Lai, Rossa W. K. Chiu, and Y. M. Dennis Lo
      PNAS March 17, 2015 112 (11) E1317-E1325; first published February 2, 2015. https://doi.org/10.1073/pnas.1500076112

      See companion article:

      • Size selection in circulating tumor DNA
        - Mar 02, 2015
    • You have access
      Quorum-sensing Salmonella selectively trigger protein expression within tumors
      Charles A. Swofford, Nele Van Dessel, and Neil S. Forbes
      PNAS March 17, 2015 112 (11) 3457-3462; first published March 3, 2015. https://doi.org/10.1073/pnas.1414558112
    • You have access
      Insulin resistance in brain alters dopamine turnover and causes behavioral disorders
      Andre Kleinridders, Weikang Cai, Laura Cappellucci, Armen Ghazarian, William R. Collins, Sara G. Vienberg, Emmanuel N. Pothos, and C. Ronald Kahn
      PNAS March 17, 2015 112 (11) 3463-3468; first published March 2, 2015. https://doi.org/10.1073/pnas.1500877112
    • You have access
      The RNA binding protein FXR1 is a new driver in the 3q26-29 amplicon and predicts poor prognosis in human cancers
      Jun Qian, Mohamed Hassanein, Megan D. Hoeksema, Bradford K. Harris, Yong Zou, Heidi Chen, Pengcheng Lu, Rosana Eisenberg, Jing Wang, Allan Espinosa, Xiangming Ji, Fredrick T. Harris, S. M. Jamshedur Rahman, and Pierre P. Massion
      PNAS March 17, 2015 112 (11) 3469-3474; first published March 2, 2015. https://doi.org/10.1073/pnas.1421975112
    • You have access
      Alpha-carboxy nucleoside phosphonates as universal nucleoside triphosphate mimics
      Jan Balzarini, Kalyan Das, Jean A. Bernatchez, Sergio E. Martinez, Marianne Ngure, Sarah Keane, Alan Ford, Nuala Maguire, Niki Mullins, Jubi John, Youngju Kim, Wim Dehaen, Johan Vande Voorde, Sandra Liekens, Lieve Naesens, Matthias Götte, Anita R. Maguire, and Eddy Arnold
      PNAS March 17, 2015 112 (11) 3475-3480; first published March 2, 2015. https://doi.org/10.1073/pnas.1420233112
    • You have access
      Macronutrient balance, reproductive function, and lifespan in aging mice
      Samantha M. Solon-Biet, Kirsty A. Walters, Ulla K. Simanainen, Aisling C. McMahon, Kari Ruohonen, John William O. Ballard, David Raubenheimer, David J. Handelsman, David G. Le Couteur, and Stephen J. Simpson
      PNAS March 17, 2015 112 (11) 3481-3486; first published March 2, 2015. https://doi.org/10.1073/pnas.1422041112
    • Open Access
      Lrp4 in osteoblasts suppresses bone formation and promotes osteoclastogenesis and bone resorption
      Lei Xiong, Ji-Ung Jung, Haitao Wu, Wen-Fang Xia, Jin-Xiu Pan, Chengyong Shen, Lin Mei, and Wen-Cheng Xiong
      PNAS March 17, 2015 112 (11) 3487-3492; first published March 2, 2015. https://doi.org/10.1073/pnas.1419714112
    • Open Access
      PF-06463922 is a potent and selective next-generation ROS1/ALK inhibitor capable of blocking crizotinib-resistant ROS1 mutations
      Helen Y. Zou, Qiuhua Li, Lars D. Engstrom, Melissa West, Vicky Appleman, Katy A. Wong, Michele McTigue, Ya-Li Deng, Wei Liu, Alexei Brooun, Sergei Timofeevski, Scott R. P. McDonnell, Ping Jiang, Matthew D. Falk, Patrick B. Lappin, Timothy Affolter, Tim Nichols, Wenyue Hu, Justine Lam, Ted W. Johnson, Tod Smeal, Al Charest, and Valeria R. Fantin
      PNAS March 17, 2015 112 (11) 3493-3498; first published March 2, 2015. https://doi.org/10.1073/pnas.1420785112
    • You have access
      p63 sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling
      Elisa Maria Memmi, Anna Giulia Sanarico, Arianna Giacobbe, Angelo Peschiaroli, Valentina Frezza, Angelo Cicalese, Federica Pisati, Daniela Tosoni, Huiqing Zhou, Giovanni Tonon, Alexey Antonov, Gerry Melino, Pier Giuseppe Pelicci, and Francesca Bernassola
      PNAS March 17, 2015 112 (11) 3499-3504; first published March 4, 2015. https://doi.org/10.1073/pnas.1500762112
  • Microbiology

    • You have access
      Disentangling mechanisms that mediate the balance between stochastic and deterministic processes in microbial succession
      Francisco Dini-Andreote, James C. Stegen, Jan Dirk van Elsas, and Joana Falcão Salles
      PNAS March 17, 2015 112 (11) E1326-E1332; first published March 2, 2015. https://doi.org/10.1073/pnas.1414261112
    • You have access
      NFκB activation by modified vaccinia virus as a novel strategy to enhance neutrophil migration and HIV-specific T-cell responses
      Mauro Di Pilato, Ernesto Mejías-Pérez, Manuela Zonca, Beatriz Perdiguero, Carmen Elena Gómez, Marianna Trakala, Jacobo Nieto, José Luis Nájera, Carlos Oscar S. Sorzano, Christophe Combadière, Giuseppe Pantaleo, Lourdes Planelles, and Mariano Esteban
      PNAS March 17, 2015 112 (11) E1333-E1342; first published March 4, 2015. https://doi.org/10.1073/pnas.1424341112
    • Open Access
      Origin of the HIV-1 group O epidemic in western lowland gorillas
      Mirela D’arc, Ahidjo Ayouba, Amandine Esteban, Gerald H. Learn, Vanina Boué, Florian Liegeois, Lucie Etienne, Nikki Tagg, Fabian H. Leendertz, Christophe Boesch, Nadège F. Madinda, Martha M. Robbins, Maryke Gray, Amandine Cournil, Marcel Ooms, Michael Letko, Viviana A. Simon, Paul M. Sharp, Beatrice H. Hahn, Eric Delaporte, Eitel Mpoudi Ngole, and Martine Peeters
      PNAS March 17, 2015 112 (11) E1343-E1352; first published March 2, 2015. https://doi.org/10.1073/pnas.1502022112
    • You have access
      Retroviral vectors elevate coexpressed protein levels in trans through cap-dependent translation
      Yongqiang Gou, Hyewon Byun, Adam E. Zook, Gurvani B. Singh, Andrea K. Nash, Mary M. Lozano, and Jaquelin P. Dudley
      PNAS March 17, 2015 112 (11) 3505-3510; first published March 3, 2015. https://doi.org/10.1073/pnas.1420477112
    • You have access
      AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity
      Jessica M. A. Blair, Vassiliy N. Bavro, Vito Ricci, Niraj Modi, Pierpaolo Cacciotto, Ulrich Kleinekathӧfer, Paolo Ruggerone, Attilio V. Vargiu, Alison J. Baylay, Helen E. Smith, Yvonne Brandon, David Galloway, and Laura J. V. Piddock
      PNAS March 17, 2015 112 (11) 3511-3516; first published March 3, 2015. https://doi.org/10.1073/pnas.1419939112
  • Neuroscience

    • You have access
      Disruption of hierarchical predictive coding during sleep
      Melanie Strauss, Jacobo D. Sitt, Jean-Remi King, Maxime Elbaz, Leila Azizi, Marco Buiatti, Lionel Naccache, Virginie van Wassenhove, and Stanislas Dehaene
      PNAS March 17, 2015 112 (11) E1353-E1362; first published March 3, 2015. https://doi.org/10.1073/pnas.1501026112
    • You have access
      Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release
      Katharina Held, Tatjana Kichko, Katrien De Clercq, Hugo Klaassen, Rieta Van Bree, Jean-Christophe Vanherck, Arnaud Marchand, Peter W. Reeh, Patrick Chaltin, Thomas Voets, and Joris Vriens
      PNAS March 17, 2015 112 (11) E1363-E1372; first published March 2, 2015. https://doi.org/10.1073/pnas.1419845112
    • You have access
      Up-regulation of lysosomal TRPML1 channels is essential for lysosomal adaptation to nutrient starvation
      Wuyang Wang, Qiong Gao, Meimei Yang, Xiaoli Zhang, Lu Yu, Maria Lawas, Xinran Li, Marthe Bryant-Genevier, Noel T. Southall, Juan Marugan, Marc Ferrer, and Haoxing Xu
      PNAS March 17, 2015 112 (11) E1373-E1381; first published March 2, 2015. https://doi.org/10.1073/pnas.1419669112
    • You have access
      Coding principles of the canonical cortical microcircuit in the avian brain
      • From the Cover
      Ana Calabrese and Sarah M. N. Woolley
      PNAS March 17, 2015 112 (11) 3517-3522; first published February 17, 2015. https://doi.org/10.1073/pnas.1408545112

      See companion article:

      • Cortical computation in mammals and birds
        - Mar 09, 2015
    • You have access
      KCC2 activity is critical in limiting the onset and severity of status epilepticus
      Liliya Silayeva, Tarek Z. Deeb, Rochelle M. Hines, Matt R. Kelley, Michaelanne B. Munoz, Henry H. C. Lee, Nicholas J. Brandon, John Dunlop, Jaime Maguire, Paul A. Davies, and Stephen J. Moss
      PNAS March 17, 2015 112 (11) 3523-3528; first published March 2, 2015. https://doi.org/10.1073/pnas.1415126112
    • You have access
      Stochastic transitions into silence cause noise correlations in cortical circuits
      Gabriela Mochol, Ainhoa Hermoso-Mendizabal, Shuzo Sakata, Kenneth D. Harris, and Jaime de la Rocha
      PNAS March 17, 2015 112 (11) 3529-3534; first published March 4, 2015. https://doi.org/10.1073/pnas.1410509112
    • Open Access
      Cortically projecting basal forebrain parvalbumin neurons regulate cortical gamma band oscillations
      Tae Kim, Stephen Thankachan, James T. McKenna, James M. McNally, Chun Yang, Jee Hyun Choi, Lichao Chen, Bernat Kocsis, Karl Deisseroth, Robert E. Strecker, Radhika Basheer, Ritchie E. Brown, and Robert W. McCarley
      PNAS March 17, 2015 112 (11) 3535-3540; first published March 2, 2015. https://doi.org/10.1073/pnas.1413625112
    • Open Access
      Modeling memory consolidation during posttraining periods in cerebellovestibular learning
      Tadashi Yamazaki, Soichi Nagao, William Lennon, and Shigeru Tanaka
      PNAS March 17, 2015 112 (11) 3541-3546; first published March 3, 2015. https://doi.org/10.1073/pnas.1413798112
  • Pharmacology

    • You have access
      Glutathione and multidrug resistance protein transporter mediate a self-propelled disposal of bismuth in human cells
      Yifan Hong, Yau-Tsz Lai, Godfrey Chi-Fung Chan, and Hongzhe Sun
      PNAS March 17, 2015 112 (11) 3211-3216; first published March 3, 2015. https://doi.org/10.1073/pnas.1421002112

      See companion article:

      • Systems pharmacology for metallodrugs
        - Mar 30, 2015
  • Physiology

    • You have access
      Activation of protein synthesis in mouse uterine epithelial cells by estradiol-17β is mediated by a PKC–ERK1/2–mTOR signaling pathway
      Yuxiang Wang, Liyin Zhu, Satu Kuokkanen, and Jeffrey W. Pollard
      PNAS March 17, 2015 112 (11) E1382-E1391; first published March 2, 2015. https://doi.org/10.1073/pnas.1418973112
    • You have access
      Four basic residues critical for the ion selectivity and pore blocker sensitivity of TMEM16A calcium-activated chloride channels
      Christian J. Peters, Haibo Yu, Jason Tien, Yuh Nung Jan, Min Li, and Lily Yeh Jan
      PNAS March 17, 2015 112 (11) 3547-3552; first published March 2, 2015. https://doi.org/10.1073/pnas.1502291112
  • Plant Biology

    • You have access
      Thioredoxin, a master regulator of the tricarboxylic acid cycle in plant mitochondria
      Danilo M. Daloso, Karolin Müller, Toshihiro Obata, Alexandra Florian, Takayuki Tohge, Alexandra Bottcher, Christophe Riondet, Laetitia Bariat, Fernando Carrari, Adriano Nunes-Nesi, Bob B. Buchanan, Jean-Philippe Reichheld, Wagner L. Araújo, and Alisdair R. Fernie
      PNAS March 17, 2015 112 (11) E1392-E1400; first published February 2, 2015. https://doi.org/10.1073/pnas.1424840112

      See companion article:

      • Mitochondrial metabolism regulated by thioredoxin
        - Mar 09, 2015
    • You have access
      Regulatory link between DNA methylation and active demethylation in Arabidopsis
      Mingguang Lei, Huiming Zhang, Russell Julian, Kai Tang, Shaojun Xie, and Jian-Kang Zhu
      PNAS March 17, 2015 112 (11) 3553-3557; first published March 2, 2015. https://doi.org/10.1073/pnas.1502279112
    • You have access
      Arabidopsis OR proteins are the major posttranscriptional regulators of phytoene synthase in controlling carotenoid biosynthesis
      Xiangjun Zhou, Ralf Welsch, Yong Yang, Daniel Álvarez, Matthias Riediger, Hui Yuan, Tara Fish, Jiping Liu, Theodore W. Thannhauser, and Li Li
      PNAS March 17, 2015 112 (11) 3558-3563; first published February 9, 2015. https://doi.org/10.1073/pnas.1420831112
    • You have access
      Improving recombinant Rubisco biogenesis, plant photosynthesis and growth by coexpressing its ancillary RAF1 chaperone
      Spencer M. Whitney, Rosemary Birch, Celine Kelso, Jennifer L. Beck, and Maxim V. Kapralov
      PNAS March 17, 2015 112 (11) 3564-3569; first published March 2, 2015. https://doi.org/10.1073/pnas.1420536112
    • You have access
      Boosting CRISPR/Cas9 multiplex editing capability with the endogenous tRNA-processing system
      Kabin Xie, Bastian Minkenberg, and Yinong Yang
      PNAS March 17, 2015 112 (11) 3570-3575; first published March 2, 2015. https://doi.org/10.1073/pnas.1420294112
  • Systems Biology

    • You have access
      Rare variants in neuronal excitability genes influence risk for bipolar disorder
      Seth A. Ament, Szabolcs Szelinger, Gustavo Glusman, Justin Ashworth, Liping Hou, Nirmala Akula, Tatyana Shekhtman, Judith A. Badner, Mary E. Brunkow, Denise E. Mauldin, Anna-Barbara Stittrich, Katherine Rouleau, Sevilla D. Detera-Wadleigh, John I. Nurnberger Jr., Howard J. Edenberg, Elliot S. Gershon, Nicholas Schork, The Bipolar Genome Study, Nathan D. Price, Richard Gelinas, Leroy Hood, David Craig, Francis J. McMahon, John R. Kelsoe, and Jared C. Roach
      PNAS March 17, 2015 112 (11) 3576-3581; first published February 17, 2015. https://doi.org/10.1073/pnas.1424958112

Correction (Online Only)

  • You have access
    Correction for Bartesaghi et al., Inhibition of oxidative metabolism leads to p53 genetic inactivation and transformation in neural stem cells
    PNAS March 17, 2015 112 (11) E1401; first published February 20, 2015. https://doi.org/10.1073/pnas.1503132112
PreviousNext
Back to top

Browse PNAS issues

In this issue

Proceedings of the National Academy of Sciences: 112 (11)
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Cover Banner
  • Masthead (PDF)
Sign up for alerts

Jump to

  • This Week in PNAS
  • PNAS 100th Anniversary Article
  • Letters (Online Only)
  • Inner Workings
  • Commentaries
  • PNAS Plus Significance Statements
  • Physical Sciences
  • Social Sciences
  • Biological Sciences
  • Correction (Online Only)

PNAS Highlights. Top research, news, and commentary delivered straight to your inbox.

Site Logo
Powered by HighWire
  • Submit Manuscript
  • Twitter
  • Facebook
  • RSS Feeds
  • Email Alerts

Articles

  • Current Issue
  • Special Feature Articles – Most Recent
  • List of Issues

PNAS Portals

  • Anthropology
  • Chemistry
  • Classics
  • Front Matter
  • Physics
  • Sustainability Science
  • Teaching Resources

Information

  • Authors
  • Editorial Board
  • Reviewers
  • Subscribers
  • Librarians
  • Press
  • Site Map
  • PNAS Updates
  • FAQs
  • Accessibility Statement
  • Rights & Permissions
  • About
  • Contact

Feedback    Privacy/Legal

Copyright © 2021 National Academy of Sciences. Online ISSN 1091-6490