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Silencing of end-joining repair for efficient site-specific gene insertion after TALEN/CRISPR mutagenesis in Aedes aegypti
Edited by Anthony A. James, University of California, Irvine, CA, and approved February 24, 2015 (received for review February 6, 2015)

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Article Information
- Published in issue March 31, 2015.
- Published first March 16, 2015.
Article Versions
- Previous version (March 16, 2015 - 12:03).
- You are viewing the most recent version of this article.
Author Information
- Sanjay Basua,1,
- Azadeh Aryana,1,
- Justin M. Overcasha,
- Glady Hazitha Samuela,
- Michelle A. E. Andersona,
- Timothy J. Dahlemb,
- Kevin M. Mylesa,2, and
- Zach N. Adelmana,2
- aFralin Life Science Institute and Department of Entomology, Virginia Tech, Blacksburg, VA 24061; and
- bMutation Generation and Detection Core, Health Science Center Core Research Facility, University of Utah, Salt Lake City, UT 84132
Edited by Anthony A. James, University of California, Irvine, CA, and approved February 24, 2015 (received for review February 6, 2015)
Footnotes
↵1S.B. and A.A. contributed equally to this work.
- ↵2To whom correspondence may be addressed. Email: mylesk{at}vt.edu or zachadel{at}vt.edu.
Author contributions: S.B., A.A., J.M.O., G.H.S., T.J.D., K.M.M., and Z.N.A. designed research; S.B., A.A., J.M.O., G.H.S., and M.A.E.A. performed research; T.J.D. contributed new reagents/analytic tools; S.B., A.A., J.M.O., G.H.S., M.A.E.A., T.J.D., K.M.M., and Z.N.A. analyzed data; and S.B., A.A., T.J.D., K.M.M., and Z.N.A. wrote the paper.
The authors declare no conflict of interest.
This article is a PNAS Direct Submission.
This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1502370112/-/DCSupplemental.
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