Correction for Fouts et al., Balance of cellular and humoral immunity determines the level of protection by HIV vaccines in rhesus macaque models of HIV infection

doi:10.1073/pnas.1506010112

MICROBIOLOGY Correction for “Balance of cellular and humoral immunity determines the level of protection by HIV vaccines in rhesus macaque models of HIV infection,” by Timothy R. Fouts, Kenneth Bagley, Ilia J. Prado, Kathryn L. Bobb, Jennifer A. Schwartz, Rong Xu, Robert J. Zagursky, Michael A. Egan, John H. Eldridge, Celia C. LaBranche, David C. Montefiori, Hélène Le Buanec, Daniel Zagury, Ranajit Pal, George N. Pavlakis, Barbara K. Felber, Genoveffa Franchini, Shari Gordon, Monica Vaccari, George K. Lewis, Anthony L. DeVico, and Robert C. Gallo, which appeared in issue 9, March 3, 2015, of Proc Natl Acad Sci USA (112:E992–E999; first published February 13, 2015; 10.1073/pnas.1423669112).

The authors note that Fig. 3 appeared incorrectly. The corrected figure and its legend appear below.

Fig. 3.

(A) Acquisition rates for the groups in study 2. There was a significant (P = 0.03, log-rank test) reduction in the number of SHIV162P3 challenges required for infection in the rhesus macaques vaccinated with rhFLSC compared with the rhesus macaques vaccinated with rhFLSC plus Tat toxoid or rhesus macaques vaccinated with adjuvant alone. (B) Comparisons of IFN-γ ELISPOTS in rhesus macaques vaccinated with rhFLSC plus Tat toxoid versus those immunized with rhFLSC. Statistical comparisons were made by Mann–Whitney–Wilcoxon test; the P value is shown. (C) Comparisons of log ADCC EC₅₀ titers in the group vaccinated with rhFLSC alone versus rhFLSC plus Tat toxoid. Statistical comparisons were made by t tests; the P value is shown. (D) Comparisons of ADCC plateau cytotoxicity in animals vaccinated with rhFLSC alone versus rhFLSC plus Tat toxoid. Statistical comparisons made by Mann–Whitney–Wilcoxon test; the P value is shown. In B–D, mean values are shown with the wide line; bars indicate SEM.