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Table of Contents
May 12, 2015; vol. 112 no. 19
This Week in PNAS
Letters (Online Only)
- You have accessTranscranial direct current stimulation to lateral prefrontal cortex could increase meta-awareness of mind wanderingKieran C. R. Fox and Kalina ChristoffPNAS May 12, 2015 112 (19) E2414; first published April 9, 2015. https://doi.org/10.1073/pnas.1504686112
- You have accessQuestioning new answers regarding Holocene chicken domestication in ChinaJoris Peters, Ophélie Lebrasseur, Julia Best, Holly Miller, Tyr Fothergill, Keith Dobney, Richard M. Thomas, Mark Maltby, Naomi Sykes, Olivier Hanotte, Terry O’Connor, Matthew J. Collins, and Greger LarsonPNAS May 12, 2015 112 (19) E2415; first published April 17, 2015. https://doi.org/10.1073/pnas.1503579112
- You have accessReply to Peters et al.: Further discussions confirm early Holocene chicken domestication in northern ChinaHai Xiang, Jianqiang Gao, Baoquan Yu, Michael Hofreiter, and Xingbo ZhaoPNAS May 12, 2015 112 (19) E2416; first published April 17, 2015. https://doi.org/10.1073/pnas.1503956112
See companion article:
- Chicken domestication in China 10,000 years ago- Nov 24, 2014
- You have accessImmunodominant responses to the influenza virus M158–66 epitope: Stealth or protection?Carolien E. van de Sandt and Guus F. RimmelzwaanPNAS May 12, 2015 112 (19) E2417; first published April 6, 2015. https://doi.org/10.1073/pnas.1503245112
- You have accessReply to van de Sandt and Rimmelzwaan: Matching epitope display with functional avidityDerin B. Keskin, Bruce R. Reinhold, Guang Lan Zhang, Alexander R. Ivanov, Barry L. Karger, and Ellis L. ReinherzPNAS May 12, 2015 112 (19) E2418; first published April 6, 2015. https://doi.org/10.1073/pnas.1503931112
See companion article:
- Physical detection of influenza A epitopes- Feb 02, 2015
Opinion
Leading scientists discuss current issues.
- You have accessOpinion: Advancing neuroscience interactions with Cuba
- Front Matter
Mark Steven Cohen, Steven A. Hillyard, Janina R. Galler, Helen J. Neville, Mark M. Rasenick, Adam James Reeves, and John D. Van HornPNAS May 12, 2015 112 (19) 5859-5861; first published April 16, 2015. https://doi.org/10.1073/pnas.1504973112
QnAs
- You have accessQnAs with Patrick MooreJennifer ViegasPNAS May 12, 2015 112 (19) 5862-5863; first published April 20, 2015. https://doi.org/10.1073/pnas.1506484112
See companion article:
- Mitotic 4E-BP1 regulation by CDK1- Apr 16, 2015
PNAS Plus Significance Statements
Brief statements written by the authors about the significance of their papers.
Physical Sciences
Applied Physical Sciences
- You have accessSurface sum-frequency vibrational spectroscopy of nonpolar mediaShumei Sun, Chuanshan Tian, and Y. Ron ShenPNAS May 12, 2015 112 (19) 5883-5887; first published April 27, 2015. https://doi.org/10.1073/pnas.1505438112
- Open AccessStrain and the optoelectronic properties of nonplanar phosphorene monolayersMehrshad Mehboudi, Kainen Utt, Humberto Terrones, Edmund O. Harriss, Alejandro A. Pacheco SanJuan, and Salvador Barraza-LopezPNAS May 12, 2015 112 (19) 5888-5892; first published April 27, 2015. https://doi.org/10.1073/pnas.1500633112
Chemistry
- You have accessSensing of molecules using quantum dynamicsAgostino Migliore, Ron Naaman, and David N. BeratanPNAS May 12, 2015 112 (19) E2419-E2428; first published April 24, 2015. https://doi.org/10.1073/pnas.1502000112
- Open AccessChemical messages in 170-year-old champagne bottles from the Baltic Sea: Revealing tastes from the pastPhilippe Jeandet, Silke S. Heinzmann, Chloé Roullier-Gall, Clara Cilindre, Alissa Aron, Marie Alice Deville, Franco Moritz, Thomas Karbowiak, Dominique Demarville, Cyril Brun, Fabienne Moreau, Bernhard Michalke, Gérard Liger-Belair, Michael Witting, Marianna Lucio, Damien Steyer, Régis D. Gougeon, and Philippe Schmitt-KopplinPNAS May 12, 2015 112 (19) 5893-5898; first published April 20, 2015. https://doi.org/10.1073/pnas.1500783112
- You have accessVisible photoelectrochemical water splitting into H2 and O2 in a dye-sensitized photoelectrosynthesis cellLeila Alibabaei, Benjamin D. Sherman, Michael R. Norris, M. Kyle Brennaman, and Thomas J. MeyerPNAS May 12, 2015 112 (19) 5899-5902; first published April 27, 2015. https://doi.org/10.1073/pnas.1506111112
- You have accessIn vitro selection of a sodium-specific DNAzyme and its application in intracellular sensingSeyed-Fakhreddin Torabi, Peiwen Wu, Claire E. McGhee, Lu Chen, Kevin Hwang, Nan Zheng, Jianjun Cheng, and Yi LuPNAS May 12, 2015 112 (19) 5903-5908; first published April 27, 2015. https://doi.org/10.1073/pnas.1420361112
- You have accessTopology, structures, and energy landscapes of human chromosomesBin Zhang and Peter G. WolynesPNAS May 12, 2015 112 (19) 6062-6067; first published April 27, 2015. https://doi.org/10.1073/pnas.1506257112
Earth, Atmospheric, and Planetary Sciences
- You have accessDose-dependent regulation of microbial activity on sinking particles by polyunsaturated aldehydes: Implications for the carbon cycleBethanie R. Edwards, Kay D. Bidle, and Benjamin A. S. Van MooyPNAS May 12, 2015 112 (19) 5909-5914; first published April 27, 2015. https://doi.org/10.1073/pnas.1422664112
- You have accessReappraisal of hydrocarbon biomarkers in Archean rocksKatherine L. French, Christian Hallmann, Janet M. Hope, Petra L. Schoon, J. Alex Zumberge, Yosuke Hoshino, Carl A. Peters, Simon C. George, Gordon D. Love, Jochen J. Brocks, Roger Buick, and Roger E. SummonsPNAS May 12, 2015 112 (19) 5915-5920; first published April 27, 2015. https://doi.org/10.1073/pnas.1419563112
- You have accessAmplified Arctic warming by phytoplankton under greenhouse warmingJong-Yeon Park, Jong-Seong Kug, Jürgen Bader, Rebecca Rolph, and Minho KwonPNAS May 12, 2015 112 (19) 5921-5926; first published April 20, 2015. https://doi.org/10.1073/pnas.1416884112
- You have accessReconciling reported and unreported HFC emissions with atmospheric observationsMark F. Lunt, Matthew Rigby, Anita L. Ganesan, Alistair J. Manning, Ronald G. Prinn, Simon O’Doherty, Jens Mühle, Christina M. Harth, Peter K. Salameh, Tim Arnold, Ray F. Weiss, Takuya Saito, Yoko Yokouchi, Paul B. Krummel, L. Paul Steele, Paul J. Fraser, Shanlan Li, Sunyoung Park, Stefan Reimann, Martin K. Vollmer, Chris Lunder, Ove Hermansen, Norbert Schmidbauer, Michela Maione, Jgor Arduini, Dickon Young, and Peter G. SimmondsPNAS May 12, 2015 112 (19) 5927-5931; first published April 27, 2015. https://doi.org/10.1073/pnas.1420247112
Engineering
- You have accessUltrafast desorption of colloidal particles from fluid interfacesVincent Poulichet and Valeria GarbinPNAS May 12, 2015 112 (19) 5932-5937; first published April 28, 2015. https://doi.org/10.1073/pnas.1504776112
- You have accessModulation of orthogonal body waves enables high maneuverability in sidewinding locomotion
- From the Cover
Henry C. Astley, Chaohui Gong, Jin Dai, Matthew Travers, Miguel M. Serrano, Patricio A. Vela, Howie Choset, Joseph R. Mendelson III, David L. Hu, and Daniel I. GoldmanPNAS May 12, 2015 112 (19) 6200-6205; first published March 23, 2015. https://doi.org/10.1073/pnas.1418965112See companion article:
- Snake robot maneuverability- May 01, 2015
Environmental Sciences
- You have accessGeologic carbon storage is unlikely to trigger large earthquakes and reactivate faults through which CO2 could leakVictor Vilarrasa and Jesus CarreraPNAS May 12, 2015 112 (19) 5938-5943; first published April 20, 2015. https://doi.org/10.1073/pnas.1413284112
See companion article:
- CO2 can be done safely- Aug 03, 2015
- You have accessCoral symbiotic algae calcify ex hospite in partnership with bacteriaJörg C. Frommlet, Maria L. Sousa, Artur Alves, Sandra I. Vieira, David J. Suggett, and João SerôdioPNAS May 12, 2015 112 (19) 6158-6163; first published April 27, 2015. https://doi.org/10.1073/pnas.1420991112
Physics
- You have accessArchitecture and migration of an epithelium on a cylindrical wireHannah G. Yevick, Guillaume Duclos, Isabelle Bonnet, and Pascal SilberzanPNAS May 12, 2015 112 (19) 5944-5949; first published April 28, 2015. https://doi.org/10.1073/pnas.1418857112
- Open AccessHow a well-adapted immune system is organizedAndreas Mayer, Vijay Balasubramanian, Thierry Mora, and Aleksandra M. WalczakPNAS May 12, 2015 112 (19) 5950-5955; first published April 27, 2015. https://doi.org/10.1073/pnas.1421827112
- You have accessMicroscopic identification of the order parameter governing liquid–liquid transition in a molecular liquidKen-ichiro Murata and Hajime TanakaPNAS May 12, 2015 112 (19) 5956-5961; first published April 27, 2015. https://doi.org/10.1073/pnas.1501149112
Social Sciences
Economic Sciences
- You have accessContribution of air conditioning adoption to future energy use under global warmingLucas W. Davis and Paul J. GertlerPNAS May 12, 2015 112 (19) 5962-5967; first published April 27, 2015. https://doi.org/10.1073/pnas.1423558112
Psychological and Cognitive Sciences
- You have accessHeterogeneity of long-history migration explains cultural differences in reports of emotional expressivity and the functions of smilesMagdalena Rychlowska, Yuri Miyamoto, David Matsumoto, Ursula Hess, Eva Gilboa-Schechtman, Shanmukh Kamble, Hamdi Muluk, Takahiko Masuda, and Paula Marie NiedenthalPNAS May 12, 2015 112 (19) E2429-E2436; first published April 20, 2015. https://doi.org/10.1073/pnas.1413661112
- You have accessEvent representations constrain the structure of language: Sign language as a window into universally accessible linguistic biasesBrent Strickland, Carlo Geraci, Emmanuel Chemla, Philippe Schlenker, Meltem Kelepir, and Roland PfauPNAS May 12, 2015 112 (19) 5968-5973; first published April 27, 2015. https://doi.org/10.1073/pnas.1423080112
Social Sciences
- You have accessAssortative mating without assortative preferenceYu Xie, Siwei Cheng, and Xiang ZhouPNAS May 12, 2015 112 (19) 5974-5978; first published April 27, 2015. https://doi.org/10.1073/pnas.1504811112
Sustainability Science
- Open AccessOperationalizing the social-ecological systems framework to assess sustainabilityHeather M. Leslie, Xavier Basurto, Mateja Nenadovic, Leila Sievanen, Kyle C. Cavanaugh, Juan José Cota-Nieto, Brad E. Erisman, Elena Finkbeiner, Gustavo Hinojosa-Arango, Marcia Moreno-Báez, Sriniketh Nagavarapu, Sheila M. W. Reddy, Alexandra Sánchez-Rodríguez, Katherine Siegel, José Juan Ulibarria-Valenzuela, Amy Hudson Weaver, and Octavio Aburto-OropezaPNAS May 12, 2015 112 (19) 5979-5984; first published April 27, 2015. https://doi.org/10.1073/pnas.1414640112
- You have accessEnergy and material flows of megacitiesChristopher A. Kennedy, Iain Stewart, Angelo Facchini, Igor Cersosimo, Renata Mele, Bin Chen, Mariko Uda, Arun Kansal, Anthony Chiu, Kwi-gon Kim, Carolina Dubeux, Emilio Lebre La Rovere, Bruno Cunha, Stephanie Pincetl, James Keirstead, Sabine Barles, Semerdanta Pusaka, Juniati Gunawan, Michael Adegbile, Mehrdad Nazariha, Shamsul Hoque, Peter J. Marcotullio, Florencia González Otharán, Tarek Genena, Nadine Ibrahim, Rizwan Farooqui, Gemma Cervantes, and Ahmet Duran SahinPNAS May 12, 2015 112 (19) 5985-5990; first published April 27, 2015. https://doi.org/10.1073/pnas.1504315112
Biological Sciences
Agricultural Sciences
- Open AccessChemical messages in 170-year-old champagne bottles from the Baltic Sea: Revealing tastes from the pastPhilippe Jeandet, Silke S. Heinzmann, Chloé Roullier-Gall, Clara Cilindre, Alissa Aron, Marie Alice Deville, Franco Moritz, Thomas Karbowiak, Dominique Demarville, Cyril Brun, Fabienne Moreau, Bernhard Michalke, Gérard Liger-Belair, Michael Witting, Marianna Lucio, Damien Steyer, Régis D. Gougeon, and Philippe Schmitt-KopplinPNAS May 12, 2015 112 (19) 5893-5898; first published April 20, 2015. https://doi.org/10.1073/pnas.1500783112
Applied Biological Sciences
- You have accessInjury alters intrinsic functional connectivity within the primate spinal cordLi Min Chen, Arabinda Mishra, Pai-Feng Yang, Feng Wang, and John C. GorePNAS May 12, 2015 112 (19) 5991-5996; first published April 22, 2015. https://doi.org/10.1073/pnas.1424106112
- Open AccessCharge-mediated influence of the antibody variable domain on FcRn-dependent pharmacokineticsAngela Schoch, Hubert Kettenberger, Olaf Mundigl, Gerhard Winter, Julia Engert, Julia Heinrich, and Thomas EmrichPNAS May 12, 2015 112 (19) 5997-6002; first published April 27, 2015. https://doi.org/10.1073/pnas.1408766112
Biochemistry
- Open AccessStructural basis of human γ-secretase assemblyLinfeng Sun, Lingyun Zhao, Guanghui Yang, Chuangye Yan, Rui Zhou, Xiaoyuan Zhou, Tian Xie, Yanyu Zhao, Shenjie Wu, Xueming Li, and Yigong ShiPNAS May 12, 2015 112 (19) 6003-6008; first published April 27, 2015. https://doi.org/10.1073/pnas.1506242112
- Open AccessHow release of phosphate from mammalian F1-ATPase generates a rotary substepJohn V. Bason, Martin G. Montgomery, Andrew G. W. Leslie, and John E. WalkerPNAS May 12, 2015 112 (19) 6009-6014; first published April 27, 2015. https://doi.org/10.1073/pnas.1506465112
- You have accessNonsense suppression in archaeaArpita Bhattacharya, Caroline Köhrer, Debabrata Mandal, and Uttam L. RajBhandaryPNAS May 12, 2015 112 (19) 6015-6020; first published April 27, 2015. https://doi.org/10.1073/pnas.1501558112
- You have accessA ΩXaV motif in the Rift Valley fever virus NSs protein is essential for degrading p62, forming nuclear filaments and virulenceNormand Cyr, Cynthia de la Fuente, Lauriane Lecoq, Irene Guendel, Philippe R. Chabot, Kylene Kehn-Hall, and James G. OmichinskiPNAS May 12, 2015 112 (19) 6021-6026; first published April 27, 2015. https://doi.org/10.1073/pnas.1503688112
- You have accessHomologous trans-editing factors with broad tRNA specificity prevent mistranslation caused by serine/threonine misactivationZiwei Liu, Oscar Vargas-Rodriguez, Yuki Goto, Eva Maria Novoa, Lluís Ribas de Pouplana, Hiroaki Suga, and Karin Musier-ForsythPNAS May 12, 2015 112 (19) 6027-6032; first published April 27, 2015. https://doi.org/10.1073/pnas.1423664112
- You have accessMajor reorientation of tRNA substrates defines specificity of dihydrouridine synthasesRobert T. Byrne, Huw T. Jenkins, Daniel T. Peters, Fiona Whelan, James Stowell, Naveed Aziz, Pavel Kasatsky, Marina V. Rodnina, Eugene V. Koonin, Andrey L. Konevega, and Alfred A. AntsonPNAS May 12, 2015 112 (19) 6033-6037; first published April 22, 2015. https://doi.org/10.1073/pnas.1500161112
- You have accessThe ribosome can discriminate the chirality of amino acids within its peptidyl-transferase centerMichael T. Englander, Joshua L. Avins, Rachel C. Fleisher, Bo Liu, Philip R. Effraim, Jiangning Wang, Klaus Schulten, Thomas S. Leyh, Ruben L. Gonzalez Jr., and Virginia W. CornishPNAS May 12, 2015 112 (19) 6038-6043; first published April 27, 2015. https://doi.org/10.1073/pnas.1424712112
- You have accessCrystal structure of the human mitochondrial chaperonin symmetrical football complexShahar Nisemblat, Oren Yaniv, Avital Parnas, Felix Frolow, and Abdussalam AzemPNAS May 12, 2015 112 (19) 6044-6049; first published April 27, 2015. https://doi.org/10.1073/pnas.1411718112
- You have accessDiabetes-associated dysregulation of O-GlcNAcylation in rat cardiac mitochondriaPartha S. Banerjee, Junfeng Ma, and Gerald W. HartPNAS May 12, 2015 112 (19) 6050-6055; first published April 27, 2015. https://doi.org/10.1073/pnas.1424017112
- Open AccessA site of varicella-zoster virus vulnerability identified by structural studies of neutralizing antibodies bound to the glycoprotein complex gHgLYi Xing, Stefan L. Oliver, TuongVi Nguyen, Claudio Ciferri, Avishek Nandi, Julie Hickman, Cinzia Giovani, Edward Yang, Giuseppe Palladino, Charles Grose, Yasushi Uematsu, Anders E. Lilja, Ann M. Arvin, and Andrea CarfíPNAS May 12, 2015 112 (19) 6056-6061; first published April 27, 2015. https://doi.org/10.1073/pnas.1501176112
Biophysics and Computational Biology
- You have accessStructure-relaxation mechanism for the response of T4 lysozyme cavity mutants to hydrostatic pressureMichael T. Lerch, Carlos J. López, Zhongyu Yang, Margaux J. Kreitman, Joseph Horwitz, and Wayne L. HubbellPNAS May 12, 2015 112 (19) E2437-E2446; first published April 27, 2015. https://doi.org/10.1073/pnas.1506505112
- You have accessArchitecture and migration of an epithelium on a cylindrical wireHannah G. Yevick, Guillaume Duclos, Isabelle Bonnet, and Pascal SilberzanPNAS May 12, 2015 112 (19) 5944-5949; first published April 28, 2015. https://doi.org/10.1073/pnas.1418857112
- Open AccessHow a well-adapted immune system is organizedAndreas Mayer, Vijay Balasubramanian, Thierry Mora, and Aleksandra M. WalczakPNAS May 12, 2015 112 (19) 5950-5955; first published April 27, 2015. https://doi.org/10.1073/pnas.1421827112
- You have accessTopology, structures, and energy landscapes of human chromosomesBin Zhang and Peter G. WolynesPNAS May 12, 2015 112 (19) 6062-6067; first published April 27, 2015. https://doi.org/10.1073/pnas.1506257112
- Open AccessMultiple stiffening effects of nanoscale knobs on human red blood cells infected with Plasmodium falciparum malaria parasiteYao Zhang, Changjin Huang, Sangtae Kim, Mahdi Golkaram, Matthew W. A. Dixon, Leann Tilley, Ju Li, Sulin Zhang, and Subra SureshPNAS May 12, 2015 112 (19) 6068-6073; first published April 27, 2015. https://doi.org/10.1073/pnas.1505584112
Cell Biology
- You have accessInverted formin 2 in focal adhesions promotes dorsal stress fiber and fibrillar adhesion formation to drive extracellular matrix assemblyColleen T. Skau, Sergey V. Plotnikov, Andrew D. Doyle, and Clare M. WatermanPNAS May 12, 2015 112 (19) E2447-E2456; first published April 27, 2015. https://doi.org/10.1073/pnas.1505035112
- Open AccessCDK1 substitutes for mTOR kinase to activate mitotic cap-dependent protein translation
- Inaugural Article
Masahiro Shuda, Celestino Velásquez, Erdong Cheng, Daniel G. Cordek, Hyun Jin Kwun, Yuan Chang, and Patrick S. MoorePNAS May 12, 2015 112 (19) 5875-5882; first published April 16, 2015. https://doi.org/10.1073/pnas.1505787112See companion article:
- QnAs with Patrick Moore- Apr 20, 2015
- You have accessInactivation of EWS reduces PGC-1α protein stability and mitochondrial homeostasisJun Hong Park, Hong-Jun Kang, Yun Kyung Lee, Hyeog Kang, Jihyun Kim, Jay H. Chung, Ji Suk Chang, Alexandra C. McPherron, and Sean Bong LeePNAS May 12, 2015 112 (19) 6074-6079; first published April 27, 2015. https://doi.org/10.1073/pnas.1504391112
Developmental Biology
- You have accessiRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signalingXue Li, Thorsten Maretzky, Gisela Weskamp, Sébastien Monette, Xiaoping Qing, Priya Darshinee A. Issuree, Howard C. Crawford, David R. McIlwain, Tak W. Mak, Jane E. Salmon, and Carl P. BlobelPNAS May 12, 2015 112 (19) 6080-6085; first published April 27, 2015. https://doi.org/10.1073/pnas.1505649112
- Open AccessNeural crest cell-derived VEGF promotes embryonic jaw extensionSophie Wiszniak, Francesca E. Mackenzie, Peter Anderson, Samuela Kabbara, Christiana Ruhrberg, and Quenten SchwarzPNAS May 12, 2015 112 (19) 6086-6091; first published April 28, 2015. https://doi.org/10.1073/pnas.1419368112
Ecology
- You have accessEnvironmental constraints drive the partitioning of the soundscape in fishes
- From the Cover
Laëtitia Ruppé, Gaël Clément, Anthony Herrel, Laurent Ballesta, Thierry Décamps, Loïc Kéver, and Eric ParmentierPNAS May 12, 2015 112 (19) 6092-6097; first published April 6, 2015. https://doi.org/10.1073/pnas.1424667112See companion article:
- Insights from marine soundscapes- Apr 30, 2015
- You have accessOn the factors that promote the diversity of herbivorous insects and plants in tropical forestsJudith X. BecerraPNAS May 12, 2015 112 (19) 6098-6103; first published April 20, 2015. https://doi.org/10.1073/pnas.1418643112
- You have accessComparative analyses of animal-tracking data reveal ecological significance of endothermy in fishes
- From the Cover
Yuuki Y. Watanabe, Kenneth J. Goldman, Jennifer E. Caselle, Demian D. Chapman, and Yannis P. PapastamatiouPNAS May 12, 2015 112 (19) 6104-6109; first published April 20, 2015. https://doi.org/10.1073/pnas.1500316112
Environmental Sciences
- You have accessDose-dependent regulation of microbial activity on sinking particles by polyunsaturated aldehydes: Implications for the carbon cycleBethanie R. Edwards, Kay D. Bidle, and Benjamin A. S. Van MooyPNAS May 12, 2015 112 (19) 5909-5914; first published April 27, 2015. https://doi.org/10.1073/pnas.1422664112
Evolution
- You have accessReappraisal of hydrocarbon biomarkers in Archean rocksKatherine L. French, Christian Hallmann, Janet M. Hope, Petra L. Schoon, J. Alex Zumberge, Yosuke Hoshino, Carl A. Peters, Simon C. George, Gordon D. Love, Jochen J. Brocks, Roger Buick, and Roger E. SummonsPNAS May 12, 2015 112 (19) 5915-5920; first published April 27, 2015. https://doi.org/10.1073/pnas.1419563112
- Open AccessBiological evidence supports an early and complex emergence of the Isthmus of PanamaChristine D. Bacon, Daniele Silvestro, Carlos Jaramillo, Brian Tilston Smith, Prosanta Chakrabarty, and Alexandre AntonelliPNAS May 12, 2015 112 (19) 6110-6115; first published April 27, 2015. https://doi.org/10.1073/pnas.1423853112
See companion article:
- Biotic interchange across the Isthmus of Panama- Oct 21, 2015
Genetics
- You have accessdNTP pool levels modulate mutator phenotypes of error-prone DNA polymerase ε variantsLindsey N. Williams, Lisette Marjavaara, Gary M. Knowels, Eric M. Schultz, Edward J. Fox, Andrei Chabes, and Alan J. HerrPNAS May 12, 2015 112 (19) E2457-E2466; first published March 31, 2015. https://doi.org/10.1073/pnas.1422948112
See companion article:
- Cancer-linked Polδ variant expands dNTP pools- Mar 31, 2015
See companion article:
- Mechanism of a mutator phenotype- Apr 30, 2015
- You have accessColon cancer-associated mutator DNA polymerase δ variant causes expansion of dNTP pools increasing its own infidelityTony M. Mertz, Sushma Sharma, Andrei Chabes, and Polina V. ShcherbakovaPNAS May 12, 2015 112 (19) E2467-E2476; first published March 31, 2015. https://doi.org/10.1073/pnas.1422934112
See companion article:
- Modulating Pol ε mutators- Mar 31, 2015
See companion article:
- Mechanism of a mutator phenotype- Apr 30, 2015
- You have accessTranscriptome dynamics of developing maize leaves and genomewide prediction of cis elements and their cognate transcription factorsChun-Ping Yu, Sean Chun-Chang Chen, Yao-Ming Chang, Wen-Yu Liu, Hsin-Hung Lin, Jinn-Jy Lin, Hsiang June Chen, Yu-Ju Lu, Yi-Hsuan Wu, Mei-Yeh Jade Lu, Chen-Hua Lu, Arthur Chun-Chieh Shih, Maurice Sun-Ben Ku, Shin-Han Shiu, Shu-Hsing Wu, and Wen-Hsiung LiPNAS May 12, 2015 112 (19) E2477-E2486; first published April 27, 2015. https://doi.org/10.1073/pnas.1500605112
- Open AccessCharacterizing the in vivo role of trehalose in Saccharomyces cerevisiae using the AGT1 transporterPatrick A. Gibney, Ariel Schieler, Jonathan C. Chen, Joshua D. Rabinowitz, and David BotsteinPNAS May 12, 2015 112 (19) 6116-6121; first published April 27, 2015. https://doi.org/10.1073/pnas.1506289112
See companion article:
- Trehalose is sufficient for anhydrobiosis in yeast- Apr 27, 2015
- You have accessIncreasing intracellular trehalose is sufficient to confer desiccation tolerance to Saccharomyces cerevisiaeHugo Tapia, Lindsey Young, Douglas Fox, Carolyn R. Bertozzi, and Douglas KoshlandPNAS May 12, 2015 112 (19) 6122-6127; first published April 27, 2015. https://doi.org/10.1073/pnas.1506415112
See companion article:
- In vivo role of trehalose in yeast- Apr 27, 2015
- You have accessMultiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancerHuiling He, Wei Li, Sandya Liyanarachchi, Mukund Srinivas, Yanqiang Wang, Keiko Akagi, Yao Wang, Dayong Wu, Qianben Wang, Victor Jin, David E. Symer, Rulong Shen, John Phay, Rebecca Nagy, and Albert de la ChapellePNAS May 12, 2015 112 (19) 6128-6133; first published April 27, 2015. https://doi.org/10.1073/pnas.1506255112
- You have accessGenetic differences and aberrant methylation in the apelin system predict the risk of high-altitude pulmonary edemaAastha Mishra, Samantha Kohli, Sanchi Dua, Tashi Thinlas, Ghulam Mohammad, and M. A. Qadar PashaPNAS May 12, 2015 112 (19) 6134-6139; first published April 27, 2015. https://doi.org/10.1073/pnas.1422759112
Immunology and Inflammation
- You have accessIL-33 activates tumor stroma to promote intestinal polyposisRebecca L. Maywald, Stephanie K. Doerner, Luca Pastorelli, Carlo De Salvo, Susan M. Benton, Emily P. Dawson, Denise G. Lanza, Nathan A. Berger, Sanford D. Markowitz, Heinz-Josef Lenz, Joseph H. Nadeau, Theresa T. Pizarro, and Jason D. HeaneyPNAS May 12, 2015 112 (19) E2487-E2496; first published April 27, 2015. https://doi.org/10.1073/pnas.1422445112
- You have accessIpilimumab-dependent cell-mediated cytotoxicity of regulatory T cells ex vivo by nonclassical monocytes in melanoma patientsEmanuela Romano, Monika Kusio-Kobialka, Periklis G. Foukas, Petra Baumgaertner, Christiane Meyer, Pierluigi Ballabeni, Olivier Michielin, Benjamin Weide, Pedro Romero, and Daniel E. SpeiserPNAS May 12, 2015 112 (19) 6140-6145; first published April 27, 2015. https://doi.org/10.1073/pnas.1417320112
- Open AccessNoninvasive imaging of immune responses
- From the Cover
Mohammad Rashidian, Edmund J. Keliher, Angelina M. Bilate, Joao N. Duarte, Gregory R. Wojtkiewicz, Johanne Tracey Jacobsen, Juanjo Cragnolini, Lee Kim Swee, Gabriel D. Victora, Ralph Weissleder, and Hidde L. PloeghPNAS May 12, 2015 112 (19) 6146-6151; first published April 20, 2015. https://doi.org/10.1073/pnas.1502609112See companion article:
- PET imaging for tracking innate immune response- May 01, 2015
Medical Sciences
- You have accessIntercellular chaperone transmission via exosomes contributes to maintenance of protein homeostasis at the organismal levelToshihide Takeuchi, Mari Suzuki, Nobuhiro Fujikake, H. Akiko Popiel, Hisae Kikuchi, Shiroh Futaki, Keiji Wada, and Yoshitaka NagaiPNAS May 12, 2015 112 (19) E2497-E2506; first published April 27, 2015. https://doi.org/10.1073/pnas.1412651112
- You have accessDirect conversion of human fibroblasts into functional osteoblasts by defined factorsKenta Yamamoto, Tsunao Kishida, Yoshiki Sato, Keisuke Nishioka, Akika Ejima, Hiroyoshi Fujiwara, Toshikazu Kubo, Toshiro Yamamoto, Narisato Kanamura, and Osam MazdaPNAS May 12, 2015 112 (19) 6152-6157; first published April 27, 2015. https://doi.org/10.1073/pnas.1420713112
Microbiology
- Open AccessMetabolic and trophic interactions modulate methane production by Arctic peat microbiota in response to warming
- From the Cover
Alexander Tøsdal Tveit, Tim Urich, Peter Frenzel, and Mette Marianne SvenningPNAS May 12, 2015 112 (19) E2507-E2516; first published April 27, 2015. https://doi.org/10.1073/pnas.1420797112 - You have accessCoral symbiotic algae calcify ex hospite in partnership with bacteriaJörg C. Frommlet, Maria L. Sousa, Artur Alves, Sandra I. Vieira, David J. Suggett, and João SerôdioPNAS May 12, 2015 112 (19) 6158-6163; first published April 27, 2015. https://doi.org/10.1073/pnas.1420991112
- Open AccessCas9-mediated targeting of viral RNA in eukaryotic cellsAryn A. Price, Timothy R. Sampson, Hannah K. Ratner, Arash Grakoui, and David S. WeissPNAS May 12, 2015 112 (19) 6164-6169; first published April 27, 2015. https://doi.org/10.1073/pnas.1422340112
Neuroscience
- You have accessTargeting β-arrestin2 in the treatment of l-DOPA–induced dyskinesia in Parkinson’s diseaseNikhil M. Urs, Simone Bido, Sean M. Peterson, Tanya L. Daigle, Caroline E. Bass, Raul R. Gainetdinov, Erwan Bezard, and Marc G. CaronPNAS May 12, 2015 112 (19) E2517-E2526; first published April 27, 2015. https://doi.org/10.1073/pnas.1502740112
- You have accessFunctional connectivity arises from a slow rhythmic mechanismJingfeng M. Li, William J. Bentley, and Lawrence H. SnyderPNAS May 12, 2015 112 (19) E2527-E2535; first published April 27, 2015. https://doi.org/10.1073/pnas.1419837112
- You have accessHistamine in the basolateral amygdala promotes inhibitory avoidance learning independently of hippocampusFernando Benetti, Cristiane Regina Guerino Furini, Jociane de Carvalho Myskiw, Gustavo Provensi, Maria Beatrice Passani, Elisabetta Baldi, Corrado Bucherelli, Leonardo Munari, Ivan Izquierdo, and Patrizio BlandinaPNAS May 12, 2015 112 (19) E2536-E2542; first published April 27, 2015. https://doi.org/10.1073/pnas.1506109112
- You have accessArtemin promotes functional long-distance axonal regeneration to the brainstem after dorsal root crushLaura Elisabeth Wong, Molly E. Gibson, H. Moore Arnold, Blake Pepinsky, and Eric FrankPNAS May 12, 2015 112 (19) 6170-6175; first published April 27, 2015. https://doi.org/10.1073/pnas.1502057112
- You have accessSynaptic abnormalities and cytoplasmic glutamate receptor aggregates in contactin associated protein-like 2/Caspr2 knockout neuronsOlga Varea, Maria Dolores Martin-de-Saavedra, Katherine J. Kopeikina, Britta Schürmann, Hunter J. Fleming, Jessica M. Fawcett-Patel, Anthony Bach, Seil Jang, Elior Peles, Eunjoon Kim, and Peter PenzesPNAS May 12, 2015 112 (19) 6176-6181; first published April 27, 2015. https://doi.org/10.1073/pnas.1423205112
- You have accessFunctional reconstitution of Drosophila melanogaster NMJ glutamate receptorsTae Hee Han, Poorva Dharkar, Mark L. Mayer, and Mihaela SerpePNAS May 12, 2015 112 (19) 6182-6187; first published April 27, 2015. https://doi.org/10.1073/pnas.1500458112
- You have accessRibosomal protein S6 kinase 1 signaling in prefrontal cortex controls depressive behaviorJason M. Dwyer, Jaime G. Maldonado-Avilés, Ashley E. Lepack, Ralph J. DiLeone, and Ronald S. DumanPNAS May 12, 2015 112 (19) 6188-6193; first published April 27, 2015. https://doi.org/10.1073/pnas.1505289112
Pharmacology
- Open AccessMolecular blueprint of allosteric binding sites in a homologue of the agonist-binding domain of the α7 nicotinic acetylcholine receptorRadovan Spurny, Sarah Debaveye, Ana Farinha, Ken Veys, Ann M. Vos, Thomas Gossas, John Atack, Sonia Bertrand, Daniel Bertrand, U. Helena Danielson, Gary Tresadern, and Chris UlensPNAS May 12, 2015 112 (19) E2543-E2552; first published April 27, 2015. https://doi.org/10.1073/pnas.1418289112
- You have accessAdhesion G protein-coupled receptors are activated by exposure of a cryptic tethered agonistHannah M. Stoveken, Alexander G. Hajduczok, Lei Xu, and Gregory G. TallPNAS May 12, 2015 112 (19) 6194-6199; first published April 27, 2015. https://doi.org/10.1073/pnas.1421785112
Physiology
- You have accessModulation of orthogonal body waves enables high maneuverability in sidewinding locomotion
- From the Cover
Henry C. Astley, Chaohui Gong, Jin Dai, Matthew Travers, Miguel M. Serrano, Patricio A. Vela, Howie Choset, Joseph R. Mendelson III, David L. Hu, and Daniel I. GoldmanPNAS May 12, 2015 112 (19) 6200-6205; first published March 23, 2015. https://doi.org/10.1073/pnas.1418965112See companion article:
- Snake robot maneuverability- May 01, 2015
- You have accessMissense mutation in immunodeficient patients shows the multifunctional roles of coiled-coil domain 3 (CC3) in STIM1 activationMate Maus, Amit Jairaman, Peter B. Stathopulos, Martin Muik, Marc Fahrner, Carl Weidinger, Melina Benson, Sebastian Fuchs, Stephan Ehl, Christoph Romanin, Mitsuhiko Ikura, Murali Prakriya, and Stefan FeskePNAS May 12, 2015 112 (19) 6206-6211; first published April 27, 2015. https://doi.org/10.1073/pnas.1418852112
Plant Biology
- You have accessPlastid-produced interorgannellar stress signal MEcPP potentiates induction of the unfolded protein response in endoplasmic reticulumJustin Walley, Yanmei Xiao, Jin-Zheng Wang, Edward E. Baidoo, Jay D. Keasling, Zhouxin Shen, Steven P. Briggs, and Katayoon DeheshPNAS May 12, 2015 112 (19) 6212-6217; first published April 28, 2015. https://doi.org/10.1073/pnas.1504828112
- Open AccessSyringyl lignin production in conifers: Proof of concept in a Pine tracheary element systemArmin Wagner, Yuki Tobimatsu, Lorelle Phillips, Heather Flint, Barbara Geddes, Fachuang Lu, and John RalphPNAS May 12, 2015 112 (19) 6218-6223; first published April 20, 2015. https://doi.org/10.1073/pnas.1411926112
- Open AccessCompletion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeastYang Qu, Michael L. A. E. Easson, Jordan Froese, Razvan Simionescu, Tomas Hudlicky, and Vincenzo De LucaPNAS May 12, 2015 112 (19) 6224-6229; first published April 27, 2015. https://doi.org/10.1073/pnas.1501821112
- Open AccessSolution structure of the PsIAA4 oligomerization domain reveals interaction modes for transcription factors in early auxin responseDhurvas Chandrasekaran Dinesh, Michael Kovermann, Mohanraj Gopalswamy, Antje Hellmuth, Luz Irina A. Calderón Villalobos, Hauke Lilie, Jochen Balbach, and Steffen AbelPNAS May 12, 2015 112 (19) 6230-6235; first published April 27, 2015. https://doi.org/10.1073/pnas.1424077112
Sustainability Science
- Open AccessOperationalizing the social-ecological systems framework to assess sustainabilityHeather M. Leslie, Xavier Basurto, Mateja Nenadovic, Leila Sievanen, Kyle C. Cavanaugh, Juan José Cota-Nieto, Brad E. Erisman, Elena Finkbeiner, Gustavo Hinojosa-Arango, Marcia Moreno-Báez, Sriniketh Nagavarapu, Sheila M. W. Reddy, Alexandra Sánchez-Rodríguez, Katherine Siegel, José Juan Ulibarria-Valenzuela, Amy Hudson Weaver, and Octavio Aburto-OropezaPNAS May 12, 2015 112 (19) 5979-5984; first published April 27, 2015. https://doi.org/10.1073/pnas.1414640112
- You have accessEnhancing ecosystem restoration efficiency through spatial and temporal coordinationThomas M. Neeson, Michael C. Ferris, Matthew W. Diebel, Patrick J. Doran, Jesse R. O’Hanley, and Peter B. McIntyrePNAS May 12, 2015 112 (19) 6236-6241; first published April 27, 2015. https://doi.org/10.1073/pnas.1423812112
Corrections (Online Only)
- You have accessCorrection for Jacques et al., Differentiation of antiinflammatory and antitumorigenic properties of stabilized enantiomers of thalidomide analogsPNAS May 12, 2015 112 (19) E2553; first published April 14, 2015. https://doi.org/10.1073/pnas.1506548112
- You have accessCorrection for Brodersen et al., Isoprenoid biosynthesis is required for miRNA function and affects membrane association of ARGONAUTE 1 in ArabidopsisPNAS May 12, 2015 112 (19) E2554; first published April 16, 2015. https://doi.org/10.1073/pnas.1506636112
- You have accessCorrection for Rosas et al., Integration of responses within and across Arabidopsis natural accessions uncovers loci controlling root systems architecturePNAS May 12, 2015 112 (19) E2555; first published April 21, 2015. https://doi.org/10.1073/pnas.1507065112
- You have accessCorrection for Chew et al., Multiscale digital Arabidopsis predicts individual organ and whole-organism growthPNAS May 12, 2015 112 (19) E2556; first published April 22, 2015. https://doi.org/10.1073/pnas.1506983112
Commentaries
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