Proceedings of the National Academy of Sciences: 112 (30)

New Research In

July 28, 2015; vol. 112 no. 30

This Week in PNAS

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In This Issue
PNAS July 28, 2015 112 (30) 9141-9142; https://doi.org/10.1073/iti3015112

Letters (Online Only)

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Electric vehicle footprint analysis is misleading
Assaf P. Oron

PNAS July 28, 2015 112 (30) E3973; published ahead of print July 21, 2015. https://doi.org/10.1073/pnas.1508685112
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Reply to Oron: Electric vehicles provide an opportunity to reduce environmental health effects of transportation
Christopher W. Tessum, Jason D. Hill, and Julian D. Marshall

PNAS July 28, 2015 112 (30) E3974; published ahead of print July 21, 2015. https://doi.org/10.1073/pnas.1510395112
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Expression quantitative trait loci regulate HNF4A and PTBP1 expression in human brains
Guiyou Liu, Xinjie Bao, and Renzhi Wang

PNAS July 28, 2015 112 (30) E3975; published ahead of print June 29, 2015. https://doi.org/10.1073/pnas.1509048112
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Reply to Liu et al.: HNF4A and PTBP1 expression in the brain of neurodegenerative disease patients
Jose A. Santiago and Judith A. Potashkin

PNAS July 28, 2015 112 (30) E3976; published ahead of print June 29, 2015. https://doi.org/10.1073/pnas.1510113112

News Feature

An in-depth look at trending science issues.

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News Feature: Microbes on the mind
Front Matter
Helen H. Shen

PNAS July 28, 2015 112 (30) 9143-9145; https://doi.org/10.1073/pnas.1509590112

Commentaries

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Antenna molecule drives solar hydrogen generation
Gerald J. Meyer

PNAS July 28, 2015 112 (30) 9146-9147; published ahead of print July 21, 2015. https://doi.org/10.1073/pnas.1511569112
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Myosin light chain phosphorylation to the rescue
Henk L. Granzier and Pieter P. de Tombe

PNAS July 28, 2015 112 (30) 9148-9149; published ahead of print July 8, 2015. https://doi.org/10.1073/pnas.1511455112
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In search of the primordial actin filament
Umesh Ghoshdastider, Shimin Jiang, David Popp, and Robert C. Robinson

PNAS July 28, 2015 112 (30) 9150-9151; published ahead of print July 15, 2015. https://doi.org/10.1073/pnas.1511568112
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Rectifying disordered brain dynamics to improve cognition in schizophrenia
Cameron S. Carter

PNAS July 28, 2015 112 (30) 9152-9153; published ahead of print July 8, 2015. https://doi.org/10.1073/pnas.1511091112

PNAS Plus Significance Statements

Brief statements written by the authors about the significance of their papers.

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PNAS Plus Significance Statements
PNAS July 28, 2015 112 (30) 9154-9157; https://doi.org/10.1073/pnas.ss11230

The Dynamics of Change in Multiethnic Societies Special Feature (Free Online)

Introduction
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  Dynamics of change in multiethnic societies
  From the Cover
  
  Linda R. Manzanilla
  
  PNAS July 28, 2015 112 (30) 9174-9175; published ahead of print July 6, 2015. https://doi.org/10.1073/pnas.1511469112
Perspectives
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  Theories of ethnicity and the dynamics of ethnic change in multiethnic societies
  Richard E. Blanton
  
  PNAS July 28, 2015 112 (30) 9176-9181; published ahead of print March 16, 2015. https://doi.org/10.1073/pnas.1421406112
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  Different types of multiethnic societies and different patterns of development and change in the prehistoric Near East
  Marcella Frangipane
  
  PNAS July 28, 2015 112 (30) 9182-9189; published ahead of print May 26, 2015. https://doi.org/10.1073/pnas.1419883112
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  Multiethnicity, pluralism, and migration in the south central Andes: An alternate path to state expansion
  Paul S. Goldstein
  
  PNAS July 28, 2015 112 (30) 9202-9209; published ahead of print July 20, 2015. https://doi.org/10.1073/pnas.1500487112
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  Dynamics of change in multiethnic societies: An archaeological perspective from colonial North America
  Kent G. Lightfoot
  
  PNAS July 28, 2015 112 (30) 9216-9223; published ahead of print April 13, 2015. https://doi.org/10.1073/pnas.1422190112
Research Articles
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  Early Bronze Age migrants and ethnicity in the Middle Eastern mountain zone
  Mitchell S. Rothman
  
  PNAS July 28, 2015 112 (30) 9190-9195; published ahead of print June 15, 2015. https://doi.org/10.1073/pnas.1502220112
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  Symbolic bones and interethnic violence in a frontier zone, northwest Mexico, ca. 500–900 C.E.
  Ben A. Nelson and Debra L. Martin
  
  PNAS July 28, 2015 112 (30) 9196-9201; published ahead of print May 4, 2015. https://doi.org/10.1073/pnas.1422337112
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  Cooperation and tensions in multiethnic corporate societies using Teotihuacan, Central Mexico, as a case study
  Linda R. Manzanilla
  
  PNAS July 28, 2015 112 (30) 9210-9215; published ahead of print March 16, 2015. https://doi.org/10.1073/pnas.1419881112
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  Imperial expansion, public investment, and the long path of history: China’s initial political unification and its aftermath
  Hui Fang, Gary M. Feinman, and Linda M. Nicholas
  
  PNAS July 28, 2015 112 (30) 9224-9229; published ahead of print March 16, 2015. https://doi.org/10.1073/pnas.1419157112

Physical Sciences

Applied Physical Sciences
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  Mechanically patterning the embryonic airway epithelium
  Victor D. Varner, Jason P. Gleghorn, Erin Miller, Derek C. Radisky, and Celeste M. Nelson
  
  PNAS July 28, 2015 112 (30) 9230-9235; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1504102112
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  High-resolution in vivo imaging of mouse brain through the intact skull
  Jung-Hoon Park, Wei Sun, and Meng Cui
  
  PNAS July 28, 2015 112 (30) 9236-9241; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1505939112
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  Effective charges and virial pressure of concentrated macroion solutions
  Niels Boon, Guillermo Ivan Guerrero-García, René van Roij, and Monica Olvera de la Cruz
  
  PNAS July 28, 2015 112 (30) 9242-9246; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1511798112
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  Self-removal of condensed water on the legs of water striders
  Qianbin Wang, Xi Yao, Huan Liu, David Quéré, and Lei Jiang
  
  PNAS July 28, 2015 112 (30) 9247-9252; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1506874112
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  Formation of surface nanodroplets under controlled flow conditions
  Xuehua Zhang, Ziyang Lu, Huanshu Tan, Lei Bao, Yinghe He, Chao Sun, and Detlef Lohse
  
  PNAS July 28, 2015 112 (30) 9253-9257; published ahead of print July 9, 2015. https://doi.org/10.1073/pnas.1506071112
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  Harvesting entropy and quantifying the transition from noise to chaos in a photon-counting feedback loop
  Aaron Morgan Hagerstrom, Thomas Edward Murphy, and Rajarshi Roy
  
  PNAS July 28, 2015 112 (30) 9258-9263; published ahead of print July 14, 2015. https://doi.org/10.1073/pnas.1506600112
Astronomy
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  Survival of planets around shrinking stellar binaries
  Diego J. Muñoz and Dong Lai
  
  PNAS July 28, 2015 112 (30) 9264-9269; published ahead of print July 9, 2015. https://doi.org/10.1073/pnas.1505671112
Chemistry
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  Differential sensing for the regio- and stereoselective identification and quantitation of glycerides
  Katharine L. Diehl, Michelle Adams Ivy, Scott Rabidoux, Stefan Matthias Petry, Günter Müller, and Eric V. Anslyn
  
  PNAS July 28, 2015 112 (30) E3977-E3986; published ahead of print July 14, 2015. https://doi.org/10.1073/pnas.1508848112
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  Light-driven generation of hydrogen: New chromophore dyads for increased activity based on Bodipy dye and Pt(diimine)(dithiolate) complexes
  Bo Zheng, Randy P. Sabatini, Wen-Fu Fu, Min-Sik Eum, William W. Brennessel, Lidong Wang, David W. McCamant, and Richard Eisenberg
  
  PNAS July 28, 2015 112 (30) E3987-E3996; published ahead of print June 26, 2015. https://doi.org/10.1073/pnas.1509310112
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  How osmolytes influence hydrophobic polymer conformations: A unified view from experiment and theory
  Jagannath Mondal, Duncan Halverson, Isaac T. S. Li, Guillaume Stirnemann, Gilbert C. Walker, and Bruce J. Berne
  
  PNAS July 28, 2015 112 (30) 9270-9275; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1511780112
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  Cysteine cathepsins are essential in lysosomal degradation of α-synuclein
  Ryan P. McGlinchey and Jennifer C. Lee
  
  PNAS July 28, 2015 112 (30) 9322-9327; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1500937112
Earth, Atmospheric, and Planetary Sciences
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  Reevaluating carbon fluxes in subduction zones, what goes down, mostly comes up
  Inaugural Article
  
  Peter B. Kelemen and Craig E. Manning
  
  PNAS July 28, 2015 112 (30) E3997-E4006; published ahead of print June 5, 2015. https://doi.org/10.1073/pnas.1507889112
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  Fault rheology beyond frictional melting
  Yan Lavallée, Takehiro Hirose, Jackie E. Kendrick, Kai-Uwe Hess, and Donald B. Dingwell
  
  PNAS July 28, 2015 112 (30) 9276-9280; published ahead of print June 29, 2015. https://doi.org/10.1073/pnas.1413608112
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  Active and widespread halogen chemistry in the tropical and subtropical free troposphere
  Siyuan Wang, Johan A. Schmidt, Sunil Baidar, Sean Coburn, Barbara Dix, Theodore K. Koenig, Eric Apel, Dene Bowdalo, Teresa L. Campos, Ed Eloranta, Mathew J. Evans, Joshua P. DiGangi, Mark A. Zondlo, Ru-Shan Gao, Julie A. Haggerty, Samuel R. Hall, Rebecca S. Hornbrook, Daniel Jacob, Bruce Morley, Bradley Pierce, Mike Reeves, Pavel Romashkin, Arnout ter Schure, and Rainer Volkamer
  
  PNAS July 28, 2015 112 (30) 9281-9286; published ahead of print June 29, 2015. https://doi.org/10.1073/pnas.1505142112
Engineering
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  Three-dimensional model of surfactant replacement therapy
  Marcel Filoche, Cheng-Feng Tai, and James B. Grotberg
  
  PNAS July 28, 2015 112 (30) 9287-9292; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1504025112
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  Enhancing electrochemical intermediate solvation through electrolyte anion selection to increase nonaqueous Li–O₂ battery capacity
  Colin M. Burke, Vikram Pande, Abhishek Khetan, Venkatasubramanian Viswanathan, and Bryan D. McCloskey
  
  PNAS July 28, 2015 112 (30) 9293-9298; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1505728112
Environmental Sciences
- Open Access
  Climate change and decadal shifts in the phenology of larval fishes in the California Current ecosystem
  Rebecca G. Asch
  
  PNAS July 28, 2015 112 (30) E4065-E4074; published ahead of print July 9, 2015. https://doi.org/10.1073/pnas.1421946112
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  Evaporative cooling over the Tibetan Plateau induced by vegetation growth
  Miaogen Shen, Shilong Piao, Su-Jong Jeong, Liming Zhou, Zhenzhong Zeng, Philippe Ciais, Deliang Chen, Mengtian Huang, Chun-Sil Jin, Laurent Z. X. Li, Yue Li, Ranga B. Myneni, Kun Yang, Gengxin Zhang, Yangjian Zhang, and Tandong Yao
  
  PNAS July 28, 2015 112 (30) 9299-9304; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1504418112
Physics
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  Absence of Jahn−Teller transition in the hexagonal Ba₃CuSb₂O₉ single crystal
  Naoyuki Katayama, Kenta Kimura, Yibo Han, Joji Nasu, Natalia Drichko, Yoshiki Nakanishi, Mario Halim, Yuki Ishiguro, Ryuta Satake, Eiji Nishibori, Masahito Yoshizawa, Takehito Nakano, Yasuo Nozue, Yusuke Wakabayashi, Sumio Ishihara, Masayuki Hagiwara, Hiroshi Sawa, and Satoru Nakatsuji
  
  PNAS July 28, 2015 112 (30) 9305-9309; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1508941112

Biological Sciences

Anthropology
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  Symbolic bones and interethnic violence in a frontier zone, northwest Mexico, ca. 500–900 C.E.
  Ben A. Nelson and Debra L. Martin
  
  PNAS July 28, 2015 112 (30) 9196-9201; published ahead of print May 4, 2015. https://doi.org/10.1073/pnas.1422337112
Applied Biological Sciences
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  Alleviation of off-target effects from vector-encoded shRNAs via codelivered RNA decoys
  Stefan Mockenhaupt, Stefanie Grosse, Daniel Rupp, Ralf Bartenschlager, and Dirk Grimm
  
  PNAS July 28, 2015 112 (30) E4007-E4016; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1510476112
Biochemistry
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  Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy
  Neil B. Blok, Dongyan Tan, Ray Yu-Ruei Wang, Pawel A. Penczek, David Baker, Frank DiMaio, Tom A. Rapoport, and Thomas Walz
  
  PNAS July 28, 2015 112 (30) E4017-E4025; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1500257112
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  Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist
  Sulan Luo, Dongting Zhangsun, Peta J. Harvey, Quentin Kaas, Yong Wu, Xiaopeng Zhu, Yuanyan Hu, Xiaodan Li, Victor I. Tsetlin, Sean Christensen, Haylie K. Romero, Melissa McIntyre, Cheryl Dowell, James C. Baxter, Keith S. Elmslie, David J. Craik, and J. Michael McIntosh
  
  PNAS July 28, 2015 112 (30) E4026-E4035; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1503617112
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  Molecular mechanism of the dual activity of 4EGI-1: Dissociating eIF4G from eIF4E but stabilizing the binding of unphosphorylated 4E-BP1
  Naotaka Sekiyama, Haribabu Arthanari, Evangelos Papadopoulos, Ricard A. Rodriguez-Mias, Gerhard Wagner, and Mélissa Léger-Abraham
  
  PNAS July 28, 2015 112 (30) E4036-E4045; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1512118112
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  Cysteine cathepsins are essential in lysosomal degradation of α-synuclein
  Ryan P. McGlinchey and Jennifer C. Lee
  
  PNAS July 28, 2015 112 (30) 9322-9327; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1500937112
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  Massively parallel enzyme kinetics reveals the substrate recognition landscape of the metalloprotease ADAMTS13
  Colin A. Kretz, Manhong Dai, Onuralp Soylemez, Andrew Yee, Karl C. Desch, David Siemieniak, Kärt Tomberg, Fyodor A. Kondrashov, Fan Meng, and David Ginsburg
  
  PNAS July 28, 2015 112 (30) 9328-9333; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1511328112
- Open Access
  Primer retention owing to the absence of RNase H1 is catastrophic for mitochondrial DNA replication
  J. Bradley Holmes, Gokhan Akman, Stuart R. Wood, Kiran Sakhuja, Susana M. Cerritelli, Chloe Moss, Mark R. Bowmaker, Howard T. Jacobs, Robert J. Crouch, and Ian J. Holt
  
  PNAS July 28, 2015 112 (30) 9334-9339; published ahead of print July 10, 2015. https://doi.org/10.1073/pnas.1503653112
Biophysics and Computational Biology
- Open Access
  Mutation-induced protein interaction kinetics changes affect apoptotic network dynamic properties and facilitate oncogenesis
  Linjie Zhao, Tanlin Sun, Jianfeng Pei, and Qi Ouyang
  
  PNAS July 28, 2015 112 (30) E4046-E4054; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1502126112
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  Mechanically patterning the embryonic airway epithelium
  Victor D. Varner, Jason P. Gleghorn, Erin Miller, Derek C. Radisky, and Celeste M. Nelson
  
  PNAS July 28, 2015 112 (30) 9230-9235; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1504102112
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  How osmolytes influence hydrophobic polymer conformations: A unified view from experiment and theory
  Jagannath Mondal, Duncan Halverson, Isaac T. S. Li, Guillaume Stirnemann, Gilbert C. Walker, and Bruce J. Berne
  
  PNAS July 28, 2015 112 (30) 9270-9275; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1511780112
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  Archaeal actin from a hyperthermophile forms a single-stranded filament
  From the Cover
  
  Tatjana Braun, Albina Orlova, Karin Valegård, Ann-Christin Lindås, Gunnar F. Schröder, and Edward H. Egelman
  
  PNAS July 28, 2015 112 (30) 9340-9345; published ahead of print June 29, 2015. https://doi.org/10.1073/pnas.1509069112
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  Vaccine-elicited antibody that neutralizes H5N1 influenza and variants binds the receptor site and polymorphic sites
  Katie L. Winarski, Natalie J. Thornburg, Yingchun Yu, Gopal Sapparapu, James. E. Crowe Jr., and Benjamin W. Spiller
  
  PNAS July 28, 2015 112 (30) 9346-9351; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1502762112
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  Conformational kinetics reveals affinities of protein conformational states
  Kyle G. Daniels, Yang Suo, and Terrence G. Oas
  
  PNAS July 28, 2015 112 (30) 9352-9357; published ahead of print July 10, 2015. https://doi.org/10.1073/pnas.1502084112
- Open Access
  Predicting the onset of period-doubling bifurcations in noisy cardiac systems
  Thomas Quail, Alvin Shrier, and Leon Glass
  
  PNAS July 28, 2015 112 (30) 9358-9363; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1424320112
Cell Biology
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  Dynamic epigenetic regulation of glioblastoma tumorigenicity through LSD1 modulation of MYC expression
  David Kozono, Jie Li, Masayuki Nitta, Oltea Sampetrean, David Gonda, Deepa S. Kushwaha, Dmitry Merzon, Valya Ramakrishnan, Shan Zhu, Kaya Zhu, Hiroko Matsui, Olivier Harismendy, Wei Hua, Ying Mao, Chang-Hyuk Kwon, Hideyuki Saya, Ichiro Nakano, Donald P. Pizzo, Scott R. VandenBerg, and Clark C. Chen
  
  PNAS July 28, 2015 112 (30) E4055-E4064; published ahead of print July 9, 2015. https://doi.org/10.1073/pnas.1501967112
- Open Access
  High-throughput analysis of yeast replicative aging using a microfluidic system
  Myeong Chan Jo, Wei Liu, Liang Gu, Weiwei Dang, and Lidong Qin
  
  PNAS July 28, 2015 112 (30) 9364-9369; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1510328112
Ecology
- Open Access
  Climate change and decadal shifts in the phenology of larval fishes in the California Current ecosystem
  Rebecca G. Asch
  
  PNAS July 28, 2015 112 (30) E4065-E4074; published ahead of print July 9, 2015. https://doi.org/10.1073/pnas.1421946112
Evolution
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  Evolutionary rewiring of gene regulatory network linkages at divergence of the echinoid subclasses
  Eric M. Erkenbrack and Eric H. Davidson
  
  PNAS July 28, 2015 112 (30) E4075-E4084; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1509845112
- Open Access
  Coupling of diversification and pH adaptation during the evolution of terrestrial Thaumarchaeota
  Cécile Gubry-Rangin, Christina Kratsch, Tom A. Williams, Alice C. McHardy, T. Martin Embley, James I. Prosser, and Daniel J. Macqueen
  
  PNAS July 28, 2015 112 (30) 9370-9375; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1419329112
- Open Access
  Ultrabithorax is essential for bacteriocyte development
  Yu Matsuura, Yoshitomo Kikuchi, Toru Miura, and Takema Fukatsu
  
  PNAS July 28, 2015 112 (30) 9376-9381; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1503371112
Genetics
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  Rsu1 regulates ethanol consumption in Drosophila and humans
  Shamsideen A. Ojelade, Tianye Jia, Aylin R. Rodan, Tao Chenyang, Julie L. Kadrmas, Anna Cattrell, Barbara Ruggeri, Pimphen Charoen, Hervé Lemaitre, Tobias Banaschewski, Christian Büchel, Arun L. W. Bokde, Fabiana Carvalho, Patricia J. Conrod, Herta Flor, Vincent Frouin, Jürgen Gallinat, Hugh Garavan, Penny A. Gowland, Andreas Heinz, Bernd Ittermann, Mark Lathrop, Steven Lubbe, Jean-Luc Martinot, Tomás Paus, Michael N. Smolka, Rainer Spanagel, Paul F. O’Reilly, Jaana Laitinen, Juha M. Veijola, Jianfeng Feng, Sylvane Desrivières, Marjo-Riitta Jarvelin, The IMAGEN Consortium, Gunter Schumann, and Adrian Rothenfluh
  
  PNAS July 28, 2015 112 (30) E4085-E4093; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1417222112
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  The spliceosome assembly factor GEMIN2 attenuates the effects of temperature on alternative splicing and circadian rhythms
  Rubén Gustavo Schlaen, Estefanía Mancini, Sabrina Elena Sanchez, Soledad Perez-Santángelo, Matías L. Rugnone, Craig G. Simpson, John W. S. Brown, Xu Zhang, Ariel Chernomoretz, and Marcelo J. Yanovsky
  
  PNAS July 28, 2015 112 (30) 9382-9387; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1504541112
- Open Access
  Chromosomal directionality of DNA mismatch repair in Escherichia coli
  A. M. Mahedi Hasan and David R. F. Leach
  
  PNAS July 28, 2015 112 (30) 9388-9393; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1505370112
Immunology and Inflammation
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  TACI deficiency leads to alternatively activated macrophage phenotype and susceptibility to Leishmania infection
  Windy R. Allman, Ranadhir Dey, Lunhua Liu, Shafiuddin Siddiqui, Adam S. Coleman, Parna Bhattacharya, Masahide Yano, Kadriye Uslu, Kazuyo Takeda, Hira L. Nakhasi, and Mustafa Akkoyunlu
  
  PNAS July 28, 2015 112 (30) E4094-E4103; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1421580112
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  High-resolution in vivo imaging of mouse brain through the intact skull
  Jung-Hoon Park, Wei Sun, and Meng Cui
  
  PNAS July 28, 2015 112 (30) 9236-9241; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1505939112
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  Opposing roles of STAT1 and STAT3 in IL-21 function in CD4⁺ T cells
  Chi-Keung Wan, Allison B. Andraski, Rosanne Spolski, Peng Li, Majid Kazemian, Jangsuk Oh, Leigh Samsel, Phillip A. Swanson II, Dorian B. McGavern, Elizabeth P. Sampaio, Alexandra F. Freeman, Joshua D. Milner, Steven M. Holland, and Warren J. Leonard
  
  PNAS July 28, 2015 112 (30) 9394-9399; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1511711112
Medical Sciences
- Open Access
  Quantification of biological aging in young adults
  Daniel W. Belsky, Avshalom Caspi, Renate Houts, Harvey J. Cohen, David L. Corcoran, Andrea Danese, HonaLee Harrington, Salomon Israel, Morgan E. Levine, Jonathan D. Schaefer, Karen Sugden, Ben Williams, Anatoli I. Yashin, Richie Poulton, and Terrie E. Moffitt
  
  PNAS July 28, 2015 112 (30) E4104-E4110; published ahead of print July 6, 2015. https://doi.org/10.1073/pnas.1506264112
- Open Access
  Functional expression of sodium-glucose transporters in cancer
  Claudio Scafoglio, Bruce A. Hirayama, Vladimir Kepe, Jie Liu, Chiara Ghezzi, Nagichettiar Satyamurthy, Neda A. Moatamed, Jiaoti Huang, Hermann Koepsell, Jorge R. Barrio, and Ernest M. Wright
  
  PNAS July 28, 2015 112 (30) E4111-E4119; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1511698112
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  A channelopathy mechanism revealed by direct calmodulin activation of TrpV4
  Stephen H. Loukin, Jinfeng Teng, and Ching Kung
  
  PNAS July 28, 2015 112 (30) 9400-9405; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1510602112
- Open Access
  Glucose-dependent acetylation of Rictor promotes targeted cancer therapy resistance
  Kenta Masui, Kazuhiro Tanaka, Shiro Ikegami, Genaro R. Villa, Huijun Yang, William H. Yong, Timothy F. Cloughesy, Kanato Yamagata, Nobutaka Arai, Webster K. Cavenee, and Paul S. Mischel
  
  PNAS July 28, 2015 112 (30) 9406-9411; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1511759112
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  Targeting of mTOR catalytic site inhibits multiple steps of the HIV-1 lifecycle and suppresses HIV-1 viremia in humanized mice
  Alonso Heredia, Nhut Le, Ronald B. Gartenhaus, Edward Sausville, Sandra Medina-Moreno, Juan C. Zapata, Charles Davis, Robert C. Gallo, and Robert R. Redfield
  
  PNAS July 28, 2015 112 (30) 9412-9417; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1511144112
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  Human anti-nucleolin recombinant immunoagent for cancer therapy
  Dario Palmieri, Timothy Richmond, Claudia Piovan, Tyler Sheetz, Nicola Zanesi, Fulvia Troise, Cindy James, Dorothee Wernicke, Fata Nyei, Timothy J. Gordon, Jessica Consiglio, Francesco Salvatore, Vincenzo Coppola, Flavia Pichiorri, Claudia De Lorenzo, and Carlo M. Croce
  
  PNAS July 28, 2015 112 (30) 9418-9423; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1507087112
- Open Access
  Matrix cross-linking–mediated mechanotransduction promotes posttraumatic osteoarthritis
  Jin-Hong Kim, Gyuseok Lee, Yoonkyung Won, Minju Lee, Ji-Sun Kwak, Churl-Hong Chun, and Jang-Soo Chun
  
  PNAS July 28, 2015 112 (30) 9424-9429; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1505700112
Microbiology
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  Limits and patterns of cytomegalovirus genomic diversity in humans
  Nicholas Renzette, Cornelia Pokalyuk, Laura Gibson, Bornali Bhattacharjee, Mark R. Schleiss, Klaus Hamprecht, Aparecida Y. Yamamoto, Marisa M. Mussi-Pinhata, William J. Britt, Jeffrey D. Jensen, and Timothy F. Kowalik
  
  PNAS July 28, 2015 112 (30) E4120-E4128; published ahead of print July 6, 2015. https://doi.org/10.1073/pnas.1501880112
- Open Access
  Structures of complexes formed by H5 influenza hemagglutinin with a potent broadly neutralizing human monoclonal antibody
  Xiaoli Xiong, Davide Corti, Junfeng Liu, Debora Pinna, Mathilde Foglierini, Lesley J. Calder, Stephen R. Martin, Yi Pu Lin, Philip A. Walker, Patrick J. Collins, Isabella Monne, Amorsolo L. Suguitan Jr., Celia Santos, Nigel J. Temperton, Kanta Subbarao, Antonio Lanzavecchia, Steven J. Gamblin, and John J. Skehel
  
  PNAS July 28, 2015 112 (30) 9430-9435; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1510816112
- Open Access
  Structural basis and functional analysis of the SARS coronavirus nsp14–nsp10 complex
  Yuanyuan Ma, Lijie Wu, Neil Shaw, Yan Gao, Jin Wang, Yuna Sun, Zhiyong Lou, Liming Yan, Rongguang Zhang, and Zihe Rao
  
  PNAS July 28, 2015 112 (30) 9436-9441; published ahead of print July 9, 2015. https://doi.org/10.1073/pnas.1508686112
- Open Access
  A multidrug resistance plasmid contains the molecular switch for type VI secretion in Acinetobacter baumannii
  Brent S. Weber, Pek Man Ly, Joshua N. Irwin, Stefan Pukatzki, and Mario F. Feldman
  
  PNAS July 28, 2015 112 (30) 9442-9447; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1502966112
Neuroscience
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  The LGI1–ADAM22 protein complex directs synapse maturation through regulation of PSD-95 function
  Kathryn L. Lovero, Yuko Fukata, Adam J. Granger, Masaki Fukata, and Roger A. Nicoll
  
  PNAS July 28, 2015 112 (30) E4129-E4137; published ahead of print July 15, 2015. https://doi.org/10.1073/pnas.1511910112
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  A computational perspective on autism
  Inaugural Article
  
  Ari Rosenberg, Jaclyn Sky Patterson, and Dora E. Angelaki
  
  PNAS July 28, 2015 112 (30) 9158-9165; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1510583112
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  Synchronizing theta oscillations with direct-current stimulation strengthens adaptive control in the human brain
  From the Cover
  
  Robert M. G. Reinhart, Julia Zhu, Sohee Park, and Geoffrey F. Woodman
  
  PNAS July 28, 2015 112 (30) 9448-9453; published ahead of print June 29, 2015. https://doi.org/10.1073/pnas.1504196112
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  Functional evolution of new and expanded attention networks in humans
  Gaurav H. Patel, Danica Yang, Emery C. Jamerson, Lawrence H. Snyder, Maurizio Corbetta, and Vincent P. Ferrera
  
  PNAS July 28, 2015 112 (30) 9454-9459; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1420395112
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  What the fly’s nose tells the fly’s brain
  From the Cover
  
  Charles F. Stevens
  
  PNAS July 28, 2015 112 (30) 9460-9465; published ahead of print July 6, 2015. https://doi.org/10.1073/pnas.1510103112
- Open Access
  Distinct speed dependence of entorhinal island and ocean cells, including respective grid cells
  Chen Sun, Takashi Kitamura, Jun Yamamoto, Jared Martin, Michele Pignatelli, Lacey J. Kitch, Mark J. Schnitzer, and Susumu Tonegawa
  
  PNAS July 28, 2015 112 (30) 9466-9471; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1511668112
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  Prefrontal neurons encode context-based response execution and inhibition in reward seeking and extinction
  David E. Moorman and Gary Aston-Jones
  
  PNAS July 28, 2015 112 (30) 9472-9477; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1507611112
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  Signaling between periglomerular cells reveals a bimodal role for GABA in modulating glomerular microcircuitry in the olfactory bulb
  Pirooz Victor Parsa, Rinaldo David D’Souza, and Sukumar Vijayaraghavan
  
  PNAS July 28, 2015 112 (30) 9478-9483; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1424406112
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  Tangential migration of neuronal precursors of glutamatergic neurons in the adult mammalian brain
  Gerald J. Sun, Yi Zhou, Ryan P. Stadel, Jonathan Moss, Jing Hui A. Yong, Shiori Ito, Nicholas K. Kawasaki, Alexander T. Phan, Justin H. Oh, Nikhil Modak, Randall R. Reed, Nicolas Toni, Hongjun Song, and Guo-li Ming
  
  PNAS July 28, 2015 112 (30) 9484-9489; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1508545112
Physiology
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  Constitutive phosphorylation of cardiac myosin regulatory light chain prevents development of hypertrophic cardiomyopathy in mice
  Chen-Ching Yuan, Priya Muthu, Katarzyna Kazmierczak, Jingsheng Liang, Wenrui Huang, Thomas C. Irving, Rosemeire M. Kanashiro-Takeuchi, Joshua M. Hare, and Danuta Szczesna-Cordary
  
  PNAS July 28, 2015 112 (30) E4138-E4146; published ahead of print June 29, 2015. https://doi.org/10.1073/pnas.1505819112
Plant Biology
- Open Access
  Navigating natural variation in herbivory-induced secondary metabolism in coyote tobacco populations using MS/MS structural analysis
  Dapeng Li, Ian T. Baldwin, and Emmanuel Gaquerel
  
  PNAS July 28, 2015 112 (30) E4147-E4155; published ahead of print July 13, 2015. https://doi.org/10.1073/pnas.1503106112
- Open Access
  Spatial and temporal regulation of biosynthesis of the plant immune signal salicylic acid
  Inaugural Article
  
  Xiao-yu Zheng, Mian Zhou, Heejin Yoo, Jose L. Pruneda-Paz, Natalie Weaver Spivey, Steve A. Kay, and Xinnian Dong
  
  PNAS July 28, 2015 112 (30) 9166-9173; published ahead of print July 2, 2015. https://doi.org/10.1073/pnas.1511182112

Corrections (Online Only)

You have access
Corrections for Elmendorf et al., Experiment, monitoring, and gradient methods used to infer climate change effects on plant communities yield consistent patterns
PNAS July 28, 2015 112 (30) E4156; published ahead of print July 1, 2015. https://doi.org/10.1073/pnas.1511529112
You have access
Correction for Sullivan et al., Spatially robust estimates of biological nitrogen (N) fixation imply substantial human alteration of the tropical N cycle
PNAS July 28, 2015 112 (30) E4157; published ahead of print June 30, 2015. https://doi.org/10.1073/pnas.1511978112
You have access
Correction for Wang et al., Glucagon receptor antibody completely suppresses type 1 diabetes phenotype without insulin by disrupting a novel diabetogenic pathway
PNAS July 28, 2015 112 (30) E4158; published ahead of print July 1, 2015. https://doi.org/10.1073/pnas.1512209112
You have access
Correction for Wexler et al., Default perception of high-speed motion
PNAS July 28, 2015 112 (30) E4159; published ahead of print July 1, 2015. https://doi.org/10.1073/pnas.1511553112

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