Skip to main content
  • Submit
  • About
    • Editorial Board
    • PNAS Staff
    • FAQ
    • Accessibility Statement
    • Rights and Permissions
    • Site Map
  • Contact
  • Journal Club
  • Subscribe
    • Subscription Rates
    • Subscriptions FAQ
    • Open Access
    • Recommend PNAS to Your Librarian
  • Log in
  • My Cart

Main menu

  • Home
  • Articles
    • Current
    • Special Feature Articles - Most Recent
    • Special Features
    • Colloquia
    • Collected Articles
    • PNAS Classics
    • List of Issues
  • Front Matter
  • News
    • For the Press
    • This Week In PNAS
    • PNAS in the News
  • Podcasts
  • Authors
    • Information for Authors
    • Editorial and Journal Policies
    • Submission Procedures
    • Fees and Licenses
  • Submit
  • About
    • Editorial Board
    • PNAS Staff
    • FAQ
    • Accessibility Statement
    • Rights and Permissions
    • Site Map
  • Contact
  • Journal Club
  • Subscribe
    • Subscription Rates
    • Subscriptions FAQ
    • Open Access
    • Recommend PNAS to Your Librarian

User menu

  • Log in
  • My Cart

Search

  • Advanced search
Home
Home

Advanced Search

  • Home
  • Articles
    • Current
    • Special Feature Articles - Most Recent
    • Special Features
    • Colloquia
    • Collected Articles
    • PNAS Classics
    • List of Issues
  • Front Matter
  • News
    • For the Press
    • This Week In PNAS
    • PNAS in the News
  • Podcasts
  • Authors
    • Information for Authors
    • Editorial and Journal Policies
    • Submission Procedures
    • Fees and Licenses

New Research In

Physical Sciences

Featured Portals

  • Physics
  • Chemistry
  • Sustainability Science

Articles by Topic

  • Applied Mathematics
  • Applied Physical Sciences
  • Astronomy
  • Computer Sciences
  • Earth, Atmospheric, and Planetary Sciences
  • Engineering
  • Environmental Sciences
  • Mathematics
  • Statistics

Social Sciences

Featured Portals

  • Anthropology
  • Sustainability Science

Articles by Topic

  • Economic Sciences
  • Environmental Sciences
  • Political Sciences
  • Psychological and Cognitive Sciences
  • Social Sciences

Biological Sciences

Featured Portals

  • Sustainability Science

Articles by Topic

  • Agricultural Sciences
  • Anthropology
  • Applied Biological Sciences
  • Biochemistry
  • Biophysics and Computational Biology
  • Cell Biology
  • Developmental Biology
  • Ecology
  • Environmental Sciences
  • Evolution
  • Genetics
  • Immunology and Inflammation
  • Medical Sciences
  • Microbiology
  • Neuroscience
  • Pharmacology
  • Physiology
  • Plant Biology
  • Population Biology
  • Psychological and Cognitive Sciences
  • Sustainability Science
  • Systems Biology
Research Article

The essential gene set of a photosynthetic organism

Benjamin E. Rubin, Kelly M. Wetmore, Morgan N. Price, Spencer Diamond, Ryan K. Shultzaberger, Laura C. Lowe, Genevieve Curtin, Adam P. Arkin, Adam Deutschbauer, and Susan S. Golden
PNAS December 1, 2015 112 (48) E6634-E6643; first published October 27, 2015; https://doi.org/10.1073/pnas.1519220112
Benjamin E. Rubin
aDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kelly M. Wetmore
bPhysical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Morgan N. Price
bPhysical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Spencer Diamond
aDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ryan K. Shultzaberger
cKavli Institute for Brain and Mind, University of California, San Diego, La Jolla, CA 92093;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Laura C. Lowe
aDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Genevieve Curtin
aDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Adam P. Arkin
bPhysical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720;
dDepartment of Bioengineering, University of California, Berkeley, CA 94720
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Adam Deutschbauer
bPhysical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Susan S. Golden
aDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: sgolden@ucsd.edu
  1. Contributed by Susan S. Golden, September 29, 2015 (sent for review July 16, 2015; reviewed by Caroline S. Harwood and William B. Whitman)

See related content:

  • Life of a phototroph
    - Nov 13, 2015
  • Article
  • Figures & SI
  • Info & Metrics
  • PDF
Loading

Online Impact

 

Article Information

vol. 112 no. 48 E6634-E6643
DOI: 
https://doi.org/10.1073/pnas.1519220112
PubMed: 
26508635

Published By: 
National Academy of Sciences
Print ISSN: 
0027-8424
Online ISSN: 
1091-6490
History: 
  • Published in issue December 1, 2015.
  • Published first October 27, 2015.


Author Information

  1. Benjamin E. Rubina,
  2. Kelly M. Wetmoreb,
  3. Morgan N. Priceb,
  4. Spencer Diamonda,
  5. Ryan K. Shultzabergerc,
  6. Laura C. Lowea,
  7. Genevieve Curtina,
  8. Adam P. Arkinb,d,
  9. Adam Deutschbauerb, and
  10. Susan S. Goldena,1
  1. aDivision of Biological Sciences, University of California, San Diego, La Jolla, CA 92093;
  2. bPhysical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720;
  3. cKavli Institute for Brain and Mind, University of California, San Diego, La Jolla, CA 92093;
  4. dDepartment of Bioengineering, University of California, Berkeley, CA 94720
  1. Contributed by Susan S. Golden, September 29, 2015 (sent for review July 16, 2015; reviewed by Caroline S. Harwood and William B. Whitman)

Footnotes

  • ↵1To whom correspondence should be addressed. Email: sgolden{at}ucsd.edu.
  • Author contributions: B.E.R., K.M.W., S.D., A.D., and S.S.G. designed research; B.E.R., K.M.W., M.N.P., R.K.S., L.C.L., and G.C. performed research; K.M.W., M.N.P., A.P.A., and A.D. contributed new reagents/analytic tools; B.E.R., M.N.P., S.D., R.K.S., and S.S.G. analyzed data; and B.E.R. and S.S.G. wrote the paper.

  • Reviewers: C.S.H., University of Washington; and W.B.W., The University of Georgia.

  • The authors declare no conflict of interest.

  • See Commentary on page 14747.

  • This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1519220112/-/DCSupplemental.

Cited By...

  • 74 Citations
  • 78 Citations
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Mutant phenotypes for thousands of bacterial genes of unknown function
    Morgan N. Price, Kelly M. Wetmore, R. Jordan Waters, Mark Callaghan, Jayashree Ray, Hualan Liu, Jennifer V. Kuehl, Ryan A. Melnyk, Jacob S. Lamson, Yumi Suh, Hans K. Carlson, Zuelma Esquivel, Harini Sadeeshkumar, Romy Chakraborty, Grant M. Zane, Benjamin E. Rubin, Judy D. Wall, Axel Visel, James Bristow, Matthew J. Blow, Adam P. Arkin, Adam M. Deutschbauer
    Nature 2018 557 7706
  • Global metabolic rewiring for improved CO2 fixation and chemical production in cyanobacteria
    Masahiro Kanno, Austin L. Carroll, Shota Atsumi
    Nature Communications 2017 8 1
  • Diversion of the long-chain acyl-ACP pool in Synechocystis to fatty alcohols through CRISPRi repression of the essential phosphate acyltransferase PlsX
    Danuta Kaczmarzyk, Ivana Cengic, Lun Yao, Elton P. Hudson
    Metabolic Engineering 2018 45
  • Unique attributes of cyanobacterial metabolism revealed by improved genome-scale metabolic modeling and essential gene analysis
    Jared T. Broddrick, Benjamin E. Rubin, David G. Welkie, Niu Du, Nathan Mih, Spencer Diamond, Jenny J. Lee, Susan S. Golden, Bernhard O. Palsson
    Proceedings of the National Academy of Sciences 2016 113 51
  • A genome-wide algal mutant library and functional screen identifies genes required for eukaryotic photosynthesis
    Xiaobo Li, Weronika Patena, Friedrich Fauser, Robert E. Jinkerson, Shai Saroussi, Moritz T. Meyer, Nina Ivanova, Jacob M. Robertson, Rebecca Yue, Ru Zhang, Josep Vilarrasa-Blasi, Tyler M. Wittkopp, Silvia Ramundo, Sean R. Blum, Audrey Goh, Matthew Laudon, Tharan Srikumar, Paul A. Lefebvre, Arthur R. Grossman, Martin C. Jonikas
    Nature Genetics 2019 51 4
  • Deciphering cyanobacterial phenotypes for fast photoautotrophic growth via isotopically nonstationary metabolic flux analysis
    Mary H. Abernathy, Jingjie Yu, Fangfang Ma, Michelle Liberton, Justin Ungerer, Whitney D. Hollinshead, Saratram Gopalakrishnan, Lian He, Costas D. Maranas, Himadri B. Pakrasi, Doug K. Allen, Yinjie J. Tang
    Biotechnology for Biofuels 2017 10 1
  • Solar-to-chemical and solar-to-fuel production from CO 2 by metabolically engineered microorganisms
    Han Min Woo
    Current Opinion in Biotechnology 2017 45
  • New Applications of Synthetic Biology Tools for Cyanobacterial Metabolic Engineering
    María Santos-Merino, Amit K. Singh, Daniel C. Ducat
    Frontiers in Bioengineering and Biotechnology 2019 7
  • Ecosystem Structure and Dynamics in the North Pacific Subtropical Gyre: New Views of an Old Ocean
    David M. Karl, Matthew J. Church
    Ecosystems 2017 20 3
  • Filling gaps in bacterial amino acid biosynthesis pathways with high-throughput genetics
    Morgan N. Price, Grant M. Zane, Jennifer V. Kuehl, Ryan A. Melnyk, Judy D. Wall, Adam M. Deutschbauer, Adam P. Arkin, Josep Casadesús
    PLOS Genetics 2018 14 1
  • Recent advances in synthetic biology of cyanobacteria
    Annesha Sengupta, Himadri B. Pakrasi, Pramod P. Wangikar
    Applied Microbiology and Biotechnology 2018 102 13
  • Identifying the Metabolic Differences of a Fast-Growth Phenotype in Synechococcus UTEX 2973
    Thomas J. Mueller, Justin L. Ungerer, Himadri B. Pakrasi, Costas D. Maranas
    Scientific Reports 2017 7 1
  • Metabolic engineering tools in model cyanobacteria
    Austin L. Carroll, Anna E. Case, Angela Zhang, Shota Atsumi
    Metabolic Engineering 2018 50
  • Redox crisis underlies conditional light–dark lethality in cyanobacterial mutants that lack the circadian regulator, RpaA
    Spencer Diamond, Benjamin E. Rubin, Ryan K. Shultzaberger, You Chen, Chase D. Barber, Susan S. Golden
    Proceedings of the National Academy of Sciences 2017 114 4
  • Terpenoid Metabolic Engineering in Photosynthetic Microorganisms
    Konstantinos Vavitsas, Michele Fabris, Claudia Vickers
    Genes 2018 9 11
  • NOT Gate Genetic Circuits to Control Gene Expression in Cyanobacteria
    Arnaud Taton, Amy T. Ma, Mizuho Ota, Susan S. Golden, James W. Golden
    ACS Synthetic Biology 2017 6 12
  • Genome-wide fitness assessment during diurnal growth reveals an expanded role of the cyanobacterial circadian clock protein KaiA
    David G. Welkie, Benjamin E. Rubin, Yong-Gang Chang, Spencer Diamond, Scott A. Rifkin, Andy LiWang, Susan S. Golden
    Proceedings of the National Academy of Sciences 2018 115 30
  • Nitrogen metabolism in cyanobacteria: metabolic and molecular control, growth consequences and biotechnological applications
    Alberto A. Esteves-Ferreira, Masami Inaba, Antoine Fort, Wagner L. Araújo, Ronan Sulpice
    Critical Reviews in Microbiology 2018 44 5
  • Giving Time Purpose: TheSynechococcus elongatusClock in a Broader Network Context
    Ryan K. Shultzaberger, Joseph S. Boyd, Spencer Diamond, Ralph J. Greenspan, Susan S. Golden
    Annual Review of Genetics 2015 49 1
  • Pangenomics Comes of Age: From Bacteria to Plant and Animal Applications
    Agnieszka A. Golicz, Philipp E. Bayer, Prem L. Bhalla, Jacqueline Batley, David Edwards
    Trends in Genetics 2020 36 2
  • The primary transcriptome of the fast-growing cyanobacterium Synechococcus elongatus UTEX 2973
    Xiaoming Tan, Shengwei Hou, Kuo Song, Jens Georg, Stephan Klähn, Xuefeng Lu, Wolfgang R. Hess
    Biotechnology for Biofuels 2018 11 1
  • The Use of Transposon Insertion Sequencing to Interrogate the Core Functional Genome of the Legume Symbiont Rhizobium leguminosarum
    Benjamin J. Perry, Mir S. Akter, Christopher K. Yost
    Frontiers in Microbiology 2016 7
  • Carbon/nitrogen homeostasis control in cyanobacteria
    Karl Forchhammer, Khaled A Selim
    FEMS Microbiology Reviews 2019
  • Genes essential for phototrophic growth by a purple alphaproteobacterium
    Jianming Yang, Liang Yin, Faith H. Lessner, Ernesto S. Nakayasu, Samuel H. Payne, Kathryn R. Fixen, Larry Gallagher, Caroline S. Harwood
    Environmental Microbiology 2017 19 9
  • Engineering the fatty acid synthesis pathway in Synechococcus elongatus PCC 7942 improves omega-3 fatty acid production
    María Santos-Merino, M. Pilar Garcillán-Barcia, Fernando de la Cruz
    Biotechnology for Biofuels 2018 11 1
  • Expanding the Cyanobacterial Nitrogen Regulatory Network: The GntR-Like Regulator PlmA Interacts with the PII-PipX Complex
    Jose I. Labella, Anna Obrebska, Javier Espinosa, Paloma Salinas, Alicia Forcada-Nadal, Lorena Tremiño, Vicente Rubio, Asunción Contreras
    Frontiers in Microbiology 2016 7
  • Rapidly moving new bacteria to model-organism status
    Hualan Liu, Adam M Deutschbauer
    Current Opinion in Biotechnology 2018 51
  • PipY, a Member of the Conserved COG0325 Family of PLP-Binding Proteins, Expands the Cyanobacterial Nitrogen Regulatory Network
    José I. Labella, Raquel Cantos, Javier Espinosa, Alicia Forcada-Nadal, Vicente Rubio, Asunción Contreras
    Frontiers in Microbiology 2017 8
  • Pooled CRISPRi screening of the cyanobacterium Synechocystis sp PCC 6803 for enhanced industrial phenotypes
    Lun Yao, Kiyan Shabestary, Sara M. Björk, Johannes Asplund-Samuelsson, Haakan N. Joensson, Michael Jahn, Elton P. Hudson
    Nature Communications 2020 11 1
  • Self-replicating shuttle vectors based on pANS, a small endogenous plasmid of the unicellular cyanobacterium Synechococcus elongatus PCC 7942
    You Chen, Arnaud Taton, Michaela Go, Ross E. London, Lindsey M. Pieper, Susan S. Golden, James W. Golden
    Microbiology 2016 162 12
  • The circadian clock and darkness control natural competence in cyanobacteria
    Arnaud Taton, Christian Erikson, Yiling Yang, Benjamin E. Rubin, Scott A. Rifkin, James W. Golden, Susan S. Golden
    Nature Communications 2020 11 1
  • Genome-Wide Determination of Gene Essentiality by Transposon Insertion Sequencing in Yeast Pichia pastoris
    Jinxiang Zhu, Ruiqing Gong, Qiaoyun Zhu, Qiulin He, Ning Xu, Yichun Xu, Menghao Cai, Xiangshan Zhou, Yuanxing Zhang, Mian Zhou
    Scientific Reports 2018 8 1
  • Genomics Approaches to Deciphering Natural Transformation in Cyanobacteria
    Kristen E. Wendt, Himadri B. Pakrasi
    Frontiers in Microbiology 2019 10
  • Emerging Species and Genome Editing Tools: Future Prospects in Cyanobacterial Synthetic Biology
    Grant A. R. Gale, Alejandra A. Schiavon Osorio, Lauren A. Mills, Baojun Wang, David J. Lea-Smith, Alistair J. McCormick
    Microorganisms 2019 7 10
  • Roles for ClpXP in regulating the circadian clock in Synechococcus elongatus
    Susan E. Cohen, Briana M. McKnight, Susan S. Golden
    Proceedings of the National Academy of Sciences 2018 115 33
  • An Amoebal Grazer of Cyanobacteria Requires Cobalamin Produced by Heterotrophic Bacteria
    Amy T. Ma, Joris Beld, Bianca Brahamsha, Harold L. Drake
    Applied and Environmental Microbiology 2017 83 10
  • DABs are inorganic carbon pumps found throughout prokaryotic phyla
    John J. Desmarais, Avi I. Flamholz, Cecilia Blikstad, Eli J. Dugan, Thomas G. Laughlin, Luke M. Oltrogge, Allen W. Chen, Kelly Wetmore, Spencer Diamond, Joy Y. Wang, David F. Savage
    Nature Microbiology 2019 4 12
  • Predicting the metabolic capabilities of Synechococcus elongatus PCC 7942 adapted to different light regimes
    Jared T. Broddrick, David G. Welkie, Denis Jallet, Susan S. Golden, Graham Peers, Bernhard O. Palsson
    Metabolic Engineering 2019 52
  • Purification and Characterisation of Malate Dehydrogenase From Synechocystis sp. PCC 6803: Biochemical Barrier of the Oxidative Tricarboxylic Acid Cycle
    Masahiro Takeya, Shoki Ito, Haruna Sukigara, Takashi Osanai
    Frontiers in Plant Science 2018 9
  • Comparative Genomics of Cyanobacterial Symbionts Reveals Distinct, Specialized Metabolism in Tropical Dysideidae Sponges
    Michelle A. Schorn, Peter A. Jordan, Sheila Podell, Jessica M. Blanton, Vinayak Agarwal, Jason S. Biggs, Eric E. Allen, Bradley S. Moore, Margaret J. McFall-Ngai
    mBio 2019 10 3
  • Mutations in Novel Lipopolysaccharide Biogenesis Genes Confer Resistance to Amoebal Grazing in Synechococcus elongatus
    Ryan Simkovsky, Emily E. Effner, Maria José Iglesias-Sánchez, Susan S. Golden, H. Goodrich-Blair
    Applied and Environmental Microbiology 2016 82 9
  • Conserved two-component Hik34-Rre1 module directly activates heat-stress inducible transcription of major chaperone and other genes inSynechococcus elongatusPCC 7942
    Ikki Kobayashi, Satoru Watanabe, Yu Kanesaki, Tomohiro Shimada, Hirofumi Yoshikawa, Kan Tanaka
    Molecular Microbiology 2017 104 2
  • Cyanobacterial Surface Display System Mediates Engineered Interspecies and Abiotic Binding
    Derek T. Fedeson, Daniel C. Ducat
    ACS Synthetic Biology 2017 6 2
  • Revisiting cyanobacterial state transitions
    Pablo I. Calzadilla, Diana Kirilovsky
    Photochemical & Photobiological Sciences 2020 19 5
  • An Approach for Predicting Essential Genes Using Multiple Homology Mapping and Machine Learning Algorithms
    Hong-Li Hua, Fa-Zhan Zhang, Abraham Alemayehu Labena, Chuan Dong, Yan-Ting Jin, Feng-Biao Guo
    BioMed Research International 2016 2016
  • CRISPRi-dCas12a: A dCas12a-Mediated CRISPR Interference for Repression of Multiple Genes and Metabolic Engineering in Cyanobacteria
    Sun Young Choi, Han Min Woo
    ACS Synthetic Biology 2020 9 9
  • Current knowledge and recent advances in understanding metabolism of the model cyanobacterium Synechocystis sp. PCC 6803
    Lauren A. Mills, Alistair J. McCormick, David J. Lea-Smith
    Bioscience Reports 2020 40 4
  • cyAbrB Transcriptional Regulators as Safety Devices To Inhibit Heterocyst Differentiation in Anabaena sp. Strain PCC 7120
    Akiyoshi Higo, Eri Nishiyama, Kota Nakamura, Yukako Hihara, Shigeki Ehira, Conrad W. Mullineaux
    Journal of Bacteriology 2019 201 17
  • Cyanobacterial multi-copy chromosomes and their replication
    Satoru Watanabe
    Bioscience, Biotechnology, and Biochemistry 2020 84 7
  • Gene essentiality, conservation index and co-evolution of genes in cyanobacteria
    Gopi Siva Sai Tiruveedula, Pramod P. Wangikar, Igor B. Rogozin
    PLOS ONE 2017 12 6
  • Genome-wide sequence transposon insertion sites and analyze the essential genes of Brucella melitensis
    Yanyan De, Congyue Dong, Yanyang Cao, Xiaolei Wang, Xiaowen Yang, Ning Wang, Cunrui Zhang, Zhen Wang, Yanli Lyu, Qingmin Wu
    Microbial Pathogenesis 2017 112
  • Modification of RSF1010-Based Broad-Host-Range Plasmids for Improved Conjugation and Cyanobacterial Bioprospecting
    Bryan Bishé, Arnaud Taton, James W. Golden
    iScience 2019 20
  • The use of genome-scale metabolic network reconstruction to predict fluxes and equilibrium composition of N-fixing versus C-fixing cells in a diazotrophic cyanobacterium, Trichodesmium erythraeum
    Joseph J. Gardner, Nanette R. Boyle
    BMC Systems Biology 2017 11 1
  • White noise functional integral for exponentially decaying memory: nucleotide distribution in bacterial genomes
    Renante R Violanda, Christopher C Bernido, M Victoria Carpio-Bernido
    Physica Scripta 2019 94 12
  • A class I fructose-1,6-bisphosphate aldolase is associated with salt stress tolerance in a halotolerant cyanobacterium Halothece sp. PCC 7418
    Tanutcha Patipong, Siripat Ngoennet, Masaki Honda, Takashi Hibino, Rungaroon Waditee-Sirisattha, Hakuto Kageyama
    Archives of Biochemistry and Biophysics 2019 672
  • The default cyanobacterial linked genome: an interactive platform based on cyanobacterial linkage networks to assist functional genomics
    Jose I. Labella, Antonio Llop, Asuncion Contreras
    FEBS Letters 2020 594 11
  • Covert Cross-Feeding Revealed by Genome-Wide Analysis of Fitness Determinants in a Synthetic Bacterial Mutualism
    Breah LaSarre, Adam M. Deutschbauer, Crystal E. Love, James B. McKinlay, M. Julia Pettinari
    Applied and Environmental Microbiology 2020 86 13
  • ePath: an online database towards comprehensive essential gene annotation for prokaryotes
    Xiangzhen Kong, Bin Zhu, Victoria N. Stone, Xiuchun Ge, Fadi E. El-Rami, Huangfu Donghai, Ping Xu
    Scientific Reports 2019 9 1
  • Classification of Complete Proteomes of Different Organisms and Protein Sets Based on Their Protein Distributions in Terms of Some Key Attributes of Proteins
    Hao-Bo Guo, Yue Ma, Gerald A. Tuskan, Xiaohan Yang, Hong Guo
    International Journal of Genomics 2018 2018
  • GapMind: Automated Annotation of Amino Acid Biosynthesis
    Morgan N. Price, Adam M. Deutschbauer, Adam P. Arkin, Steven J. Hallam
    mSystems 2020 5 3
  • Deciphering Patterns of Adaptation and Acclimation in the Transcriptome of Phaeocystis antarctica to Changing Iron Conditions 1
    Mariam R. Rizkallah, Stephan Frickenhaus, Scarlett Trimborn, Lars Harms, Ahmed Moustafa, Vladimir Benes, Steffi Gäbler‐Schwarz, Sara Beszteri, T. Mock
    Journal of Phycology 2020 56 3
  • Safety of photosynthetic Synechococcus elongatus for in vivo cyanobacteria–mammalian symbiotic therapeutics
    Kiah M. Williams, Hanjay Wang, Michael J. Paulsen, Akshara D. Thakore, Mary Rieck, Haley J. Lucian, Frederick Grady, Camille E. Hironaka, Athena J. Chien, Justin M. Farry, Hye Sook Shin, Kevin J. Jaatinen, Anahita Eskandari, Lyndsay M. Stapleton, Amanda N. Steele, Jeffrey E. Cohen, Y. Joseph Woo
    Microbial Biotechnology 2020 13 6
  • DEG 15, an update of the Database of Essential Genes that includes built-in analysis tools
    Hao Luo, Yan Lin, Tao Liu, Fei-Liao Lai, Chun-Ting Zhang, Feng Gao, Ren Zhang
    Nucleic Acids Research 2021 49 D1
  • Functional and structural characterization of PII‐like protein CutA does not support involvement in heavy metal tolerance and hints at a small‐molecule carrying/signaling role
    Khaled A. Selim, Lorena Tremiño, Clara Marco‐Marín, Vikram Alva, Javier Espinosa, Asunción Contreras, Marcus D. Hartmann, Karl Forchhammer, Vicente Rubio
    The FEBS Journal 2020
  • Heterologous Expression of Cryptomaldamide in a Cyanobacterial Host
    Arnaud Taton, Andrew Ecker, Brienna Diaz, Nathan A. Moss, Brooke Anderson, Raphael Reher, Tiago F. Leão, Ryan Simkovsky, Pieter C. Dorrestein, Lena Gerwick, William H. Gerwick, James W. Golden
    ACS Synthetic Biology 2020 9 12
  • Insights into the life of an oxygenic phototroph
    William B. Whitman
    Proceedings of the National Academy of Sciences 2015 112 48
  • Transposon Insertion Sequencing, a Global Measure of Gene Function
    Tim van Opijnen, Henry L. Levin
    Annual Review of Genetics 2020 54 1
  • A Genome-Wide, Mapped Algal Mutant Library Enables High-Throughput Genetic Studies in a Photosynthetic Eukaryote
    Xiaobo Li, Weronika Patena, Friedrich Fauser, Robert E. Jinkerson, Shai Saroussi, Nina Ivanova, Jacob M. Robertson, Rebecca Yue, Ru Zhang, Josep Vilarrasa-Blasi, Tyler M. Wittkopp, Silvia Ramundo, Sean R. Blum, Audrey Goh, Matthew Laudon, Paul A. Lefebvre, Arthur R. Grossman, Martin C. Jonikas
    SSRN Electronic Journal 2018
  • A Suggestion of Converting Protein Intrinsic Disorder to Structural Entropy Using Shannon’s Information Theory
    Hao-Bo Guo, Yue Ma, Gerald Tuskan, Hong Qin, Xiaohan Yang, Hong Guo
    Entropy 2019 21 6
  • Comparative genomics reveals new functional insights in uncultured MAST species
    Aurelie Labarre, David López-Escardó, Francisco Latorre, Guy Leonard, François Bucchini, Aleix Obiol, Corinne Cruaud, Michael E. Sieracki, Olivier Jaillon, Patrick Wincker, Klaas Vandepoele, Ramiro Logares, Ramon Massana
    The ISME Journal 2021
  • Current Status and Future Strategies to Increase Secondary Metabolite Production from Cyanobacteria
    Yujin Jeong, Sang-Hyeok Cho, Hookeun Lee, Hyung-Kyoon Choi, Dong-Myung Kim, Choul-Gyun Lee, Suhyung Cho, Byung-Kwan Cho
    Microorganisms 2020 8 12
  • Dynamic Inventory of Intermediate Metabolites of Cyanobacteria in a Diurnal Cycle
    Damini Jaiswal, Pramod P. Wangikar
    iScience 2020 23 11
  • Genes Contributing to the Unique Biology and Intrinsic Antibiotic Resistance of Enterococcus faecalis
    Michael S. Gilmore, Rauf Salamzade, Elizabeth Selleck, Noelle Bryan, Suelen S. Mello, Abigail L. Manson, Ashlee M. Earl
    mBio 2020 11 6
  • High-Throughput Functional Genomics for Energy Production
    Jacob A Fenster, Carrie A Eckert
    Current Opinion in Biotechnology 2021 67
  • Identification of Holliday junction resolvases crucial for the chloroplast nucleoid morphology and segregation
    Yusuke Kobayashi, Osami Misumi, Yoshiki Nishimura
    PLANT MORPHOLOGY 2018 30 1
  • Morphological plasticity of hyperelongated cells caused by overexpression of translation elongation factor P in Synechococcus elongatus PCC7942
    Siripat Ngoennet, Sophon Sirisattha, Masaki Honda, Takashi Hibino, Hakuto Kageyama, Rungaroon Waditee-Sirisattha
    Applied Microbiology and Biotechnology 2020 104 20
  • The effects of illumination and trophic strategy on gene expression in Chlamydomonas reinhardtii
    Victor Sanchez-Tarre, Alexandros Kiparissides
    Algal Research 2021 54
  • pH-mediated control of anti-aggregation activities of cyanobacterial and E. coli chaperonin GroELs
    Tahmina Akter, Hitoshi Nakamoto
    The Journal of Biochemistry 2020

Article usage

Article usage: October 2015 to January 2021

AbstractFullPdf
Oct 201518031295
Nov 2015142514369
Dec 20154886187451
Total 201581142021115
Jan 201647988101
Feb 20162499080
Mar 20162477694
Apr 20162207267
May 20162186460
Jun 20161827281
Jul 20161468148
Aug 20161477244
Sep 20161407063
Oct 20161397071
Nov 20161225659
Dec 20161146644
Total 20162403877812
Jan 20171276060
Feb 20171527566
Mar 20171234155
Apr 20171216641
May 20171406142
Jun 20171405972
Jul 2017944140
Aug 2017675632
Sep 2017815458
Oct 2017809639
Nov 20177613221
Dec 20174811410
Total 20171249855536
Jan 2018967025
Feb 20181039837
Mar 201811111626
Apr 20189910341
May 201811010628
Jun 201812813846
Jul 201812112839
Aug 201811110134
Sep 2018777732
Oct 20182013127
Nov 20182211631
Dec 2018208615
Total 201810181270381
Jan 2019179123
Feb 2019176412
Mar 2019268747
Apr 20191911348
May 2019228832
Jun 2019179137
Jul 2019178030
Aug 2019197555
Sep 20192014332
Oct 20192510232
Nov 20192511453
Dec 2019175831
Total 20192411106432
Jan 2020368323
Feb 2020116629
Mar 2020126031
Apr 2020449239
May 20204814247
Jun 2020278252
Jul 2020266326
Aug 20201110644
Sep 2020198739
Oct 2020378557
Nov 2020357225
Dec 20202611439
Total 20203321052451
Jan 2021195230
Total 2021195230
Total1337654143757
PreviousNext
Back to top
Article Alerts
Email Article

Thank you for your interest in spreading the word on PNAS.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
The essential gene set of a photosynthetic organism
(Your Name) has sent you a message from PNAS
(Your Name) thought you would like to see the PNAS web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Photosynthetic essential gene set
Benjamin E. Rubin, Kelly M. Wetmore, Morgan N. Price, Spencer Diamond, Ryan K. Shultzaberger, Laura C. Lowe, Genevieve Curtin, Adam P. Arkin, Adam Deutschbauer, Susan S. Golden
Proceedings of the National Academy of Sciences Dec 2015, 112 (48) E6634-E6643; DOI: 10.1073/pnas.1519220112

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Request Permissions
Share
Photosynthetic essential gene set
Benjamin E. Rubin, Kelly M. Wetmore, Morgan N. Price, Spencer Diamond, Ryan K. Shultzaberger, Laura C. Lowe, Genevieve Curtin, Adam P. Arkin, Adam Deutschbauer, Susan S. Golden
Proceedings of the National Academy of Sciences Dec 2015, 112 (48) E6634-E6643; DOI: 10.1073/pnas.1519220112
Digg logo Reddit logo Twitter logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Mendeley logo Mendeley
Proceedings of the National Academy of Sciences: 112 (48)
Table of Contents

Submit

Sign up for Article Alerts

Article Classifications

  • Biological Sciences
  • Genetics

Jump to section

  • Article
    • Abstract
    • Results
    • SI Results
    • Discussion
    • Materials and Methods
    • Acknowledgments
    • Footnotes
    • References
  • Figures & SI
  • Info & Metrics
  • PDF

You May Also be Interested in

Abstract depiction of a guitar and musical note
Science & Culture: At the nexus of music and medicine, some see disease treatments
Although the evidence is still limited, a growing body of research suggests music may have beneficial effects for diseases such as Parkinson’s.
Image credit: Shutterstock/agsandrew.
Large piece of gold
News Feature: Tracing gold's cosmic origins
Astronomers thought they’d finally figured out where gold and other heavy elements in the universe came from. In light of recent results, they’re not so sure.
Image credit: Science Source/Tom McHugh.
Dancers in red dresses
Journal Club: Friends appear to share patterns of brain activity
Researchers are still trying to understand what causes this strong correlation between neural and social networks.
Image credit: Shutterstock/Yeongsik Im.
White and blue bird
Hazards of ozone pollution to birds
Amanda Rodewald, Ivan Rudik, and Catherine Kling talk about the hazards of ozone pollution to birds.
Listen
Past PodcastsSubscribe
Goats standing in a pin
Transplantation of sperm-producing stem cells
CRISPR-Cas9 gene editing can improve the effectiveness of spermatogonial stem cell transplantation in mice and livestock, a study finds.
Image credit: Jon M. Oatley.

Similar Articles

Site Logo
Powered by HighWire
  • Submit Manuscript
  • Twitter
  • Facebook
  • RSS Feeds
  • Email Alerts

Articles

  • Current Issue
  • Special Feature Articles – Most Recent
  • List of Issues

PNAS Portals

  • Anthropology
  • Chemistry
  • Classics
  • Front Matter
  • Physics
  • Sustainability Science
  • Teaching Resources

Information

  • Authors
  • Editorial Board
  • Reviewers
  • Librarians
  • Press
  • Site Map
  • PNAS Updates

Feedback    Privacy/Legal

Copyright © 2021 National Academy of Sciences. Online ISSN 1091-6490