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Massively expedited genome-wide heritability analysis (MEGHA)
Edited by C. Thomas Caskey, Baylor College of Medicine, Houston, TX, and approved January 15, 2015 (received for review August 12, 2014)

Online Impact
Article Information
- Published in issue February 24, 2015.
- Published first February 9, 2015.
Author Information
- Tian Gea,b,c,1,
- Thomas E. Nicholsd,
- Phil H. Leeb,c,
- Avram J. Holmese,
- Joshua L. Roffmanf,
- Randy L. Bucknera,f,g,
- Mert R. Sabuncua,h,2, and
- Jordan W. Smollerb,c,1,2
- aAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital/Harvard Medical School, Charlestown, MA 02129;
- bPsychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114;
- cStanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02138;
- dDepartment of Statistics & Warwick Manufacturing Group, The University of Warwick, Coventry CV4 7AL, United Kingdom;
- eDepartment of Psychology, Yale University, New Haven, CT 06520;
- fDepartment of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, MA 02114;
- gDepartment of Psychology and Center for Brain Science, Harvard University, Cambridge, MA 02138; and
- hComputer Science and Artificial Intelligence Laboratory, Massachusetts Institute of Technology, Cambridge, MA 02139
Edited by C. Thomas Caskey, Baylor College of Medicine, Houston, TX, and approved January 15, 2015 (received for review August 12, 2014)
Footnotes
- ↵1To whom correspondence may be addressed. Email: tge1{at}mgh.harvard.edu or jsmoller{at}hms.harvard.edu.
↵2M.R.S. and J.W.S. contributed equally to this work.
Author contributions: T.G., J.L.R., R.L.B., M.R.S., and J.W.S. designed research; T.G., P.H.L., A.J.H., J.L.R., R.L.B., M.R.S., and J.W.S. performed research; T.G. and T.E.N. contributed new reagents/analytic tools; T.G., P.H.L., and A.J.H. analyzed data; and T.G., R.L.B., M.R.S., and J.W.S. wrote the paper.
The authors declare no conflict of interest.
This article is a PNAS Direct Submission.
This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1415603112/-/DCSupplemental.
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