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Table of Contents
March 29, 2016; vol. 113 no. 13
This Week in PNAS
Letters (Online Only)
- You have accessPolygyny and child health revisitedMatthias Rieger and Natascha WagnerPNAS March 29, 2016 113 (13) E1769-E1770; first published March 2, 2016. https://doi.org/10.1073/pnas.1600882113
- You have accessReply to Rieger and Wagner: Context matters when studying purportedly harmful cultural practicesDavid W. Lawson, Susan James, Esther Ngadaya, Bernard Ngowi, Sayoki G. M. Mfinanga, and Monique Borgerhoff MulderPNAS March 29, 2016 113 (13) E1771-E1772; first published March 2, 2016. https://doi.org/10.1073/pnas.1601420113
See companion article:
- Polygynous marriage and child health in Tanzania- Oct 26, 2015
- You have accessChanging fisheries productivity and food securityCody S. SzuwalskiPNAS March 29, 2016 113 (13) E1773-E1774; first published March 8, 2016. https://doi.org/10.1073/pnas.1600641113
- You have accessReply to Szuwalski: Recognizing ecological income inequality in the oceanGregory L. Britten, Michael Dowd, and Boris WormPNAS March 29, 2016 113 (13) E1775-E1776; first published March 8, 2016. https://doi.org/10.1073/pnas.1600793113
See companion article:
- Global change in fish recruitment- Dec 14, 2015
Opinion
Leading scientists discuss current issues.
- You have accessOpinion: A new paradigm for regulating genetically engineered animals that are used as food
- Front Matter
J. D. Murray and E. A. Maga
Retrospective
- You have accessAlfred Gilman: Intrepid, committed scientistHenry R. BournePNAS March 29, 2016 113 (13) 3414-3416; first published March 21, 2016. https://doi.org/10.1073/pnas.1602386113
PNAS Plus Significance Statements
Brief statements written by the authors about the significance of their papers.
Physical Sciences
Applied Physical Sciences
- You have accessUltrahigh-pressure polyamorphism in GeO2 glass with coordination number >6Yoshio Kono, Curtis Kenney-Benson, Daijo Ikuta, Yuki Shibazaki, Yanbin Wang, and Guoyin ShenPNAS March 29, 2016 113 (13) 3436-3441; first published March 14, 2016. https://doi.org/10.1073/pnas.1524304113
- Open AccessBreaking the diffraction limit of light-sheet fluorescence microscopy by RESOLFT
- From the Cover
Patrick Hoyer, Gustavo de Medeiros, Bálint Balázs, Nils Norlin, Christina Besir, Janina Hanne, Hans-Georg Kräusslich, Johann Engelhardt, Steffen J. Sahl, Stefan W. Hell, and Lars HufnagelPNAS March 29, 2016 113 (13) 3442-3446; first published March 16, 2016. https://doi.org/10.1073/pnas.1522292113 - You have accessSnapshot of sequential SNARE assembling states between membranes shows that N-terminal transient assembly initializes fusionYong Jian Wang, Feng Li, Nicolas Rodriguez, Xavier Lafosse, Christine Gourier, Eric Perez, and Frederic PincetPNAS March 29, 2016 113 (13) 3533-3538; first published March 15, 2016. https://doi.org/10.1073/pnas.1518935113
- You have accessDiscovery of fairy circles in Australia supports self-organization theoryStephan Getzin, Hezi Yizhaq, Bronwyn Bell, Todd E. Erickson, Anthony C. Postle, Itzhak Katra, Omer Tzuk, Yuval R. Zelnik, Kerstin Wiegand, Thorsten Wiegand, and Ehud MeronPNAS March 29, 2016 113 (13) 3551-3556; first published March 14, 2016. https://doi.org/10.1073/pnas.1522130113
See companion article:
- Fairy circles develop without termitaria- Sep 01, 2016
Earth, Atmospheric, and Planetary Sciences
- You have accessNew tyrannosaur from the mid-Cretaceous of Uzbekistan clarifies evolution of giant body sizes and advanced senses in tyrant dinosaursStephen L. Brusatte, Alexander Averianov, Hans-Dieter Sues, Amy Muir, and Ian B. ButlerPNAS March 29, 2016 113 (13) 3447-3452; first published March 14, 2016. https://doi.org/10.1073/pnas.1600140113
- Open AccessAntarctic ice sheet sensitivity to atmospheric CO2 variations in the early to mid-MioceneRichard Levy, David Harwood, Fabio Florindo, Francesca Sangiorgi, Robert Tripati, Hilmar von Eynatten, Edward Gasson, Gerhard Kuhn, Aradhna Tripati, Robert DeConto, Christopher Fielding, Brad Field, Nicholas Golledge, Robert McKay, Timothy Naish, Matthew Olney, David Pollard, Stefan Schouten, Franco Talarico, Sophie Warny, Veronica Willmott, Gary Acton, Kurt Panter, Timothy Paulsen, Marco Taviani, and SMS Science TeamPNAS March 29, 2016 113 (13) 3453-3458; first published February 22, 2016. https://doi.org/10.1073/pnas.1516030113
See companion article:
- Exposing Antarctica's Miocene secrets- Mar 17, 2016
See companion article:
- Dynamic early to mid-Miocene Antarctic ice sheet- Feb 22, 2016
- You have accessDynamic Antarctic ice sheet during the early to mid-Miocene
- From the Cover
Edward Gasson, Robert M. DeConto, David Pollard, and Richard H. LevyPNAS March 29, 2016 113 (13) 3459-3464; first published February 22, 2016. https://doi.org/10.1073/pnas.1516130113See companion article:
- Early to mid-Miocene Antarctic Ice Sheet dynamics- Feb 22, 2016
See companion article:
- Exposing Antarctica's Miocene secrets- Mar 17, 2016
- You have accessCarbon isotopes characterize rapid changes in atmospheric carbon dioxide during the last deglaciation
- From the Cover
Thomas K. Bauska, Daniel Baggenstos, Edward J. Brook, Alan C. Mix, Shaun A. Marcott, Vasilii V. Petrenko, Hinrich Schaefer, Jeffrey P. Severinghaus, and James E. LeePNAS March 29, 2016 113 (13) 3465-3470; first published March 14, 2016. https://doi.org/10.1073/pnas.1513868113
Engineering
- You have accessBreaking temporal symmetries for emission and absorptionYakir Hadad, Jason C. Soric, and Andrea AluPNAS March 29, 2016 113 (13) 3471-3475; first published March 16, 2016. https://doi.org/10.1073/pnas.1517363113
Environmental Sciences
- You have accessGalápagos hydroclimate of the Common Era from paired microalgal and mangrove biomarker 2H/1H valuesDaniel B. Nelson and Julian P. SachsPNAS March 29, 2016 113 (13) 3476-3481; first published March 14, 2016. https://doi.org/10.1073/pnas.1516271113
Physics
- You have accessHierarchy and extremes in selections from pools of randomized proteinsSébastien Boyer, Dipanwita Biswas, Ananda Kumar Soshee, Natale Scaramozzino, Clément Nizak, and Olivier RivoirePNAS March 29, 2016 113 (13) 3482-3487; first published March 11, 2016. https://doi.org/10.1073/pnas.1517813113
Social Sciences
Economic Sciences
- You have accessImpacts of classifying New York City students as overweightDouglas Almond, Ajin Lee, and Amy Ellen SchwartzPNAS March 29, 2016 113 (13) 3488-3491; first published March 14, 2016. https://doi.org/10.1073/pnas.1518443113
Psychological and Cognitive Sciences
- Open AccessInfants ask for help when they know they don’t knowLouise Goupil, Margaux Romand-Monnier, and Sid KouiderPNAS March 29, 2016 113 (13) 3492-3496; first published March 7, 2016. https://doi.org/10.1073/pnas.1515129113
Biological Sciences
Applied Biological Sciences
- You have accessOptogenetic skeletal muscle-powered adaptive biological machinesRitu Raman, Caroline Cvetkovic, Sebastien G. M. Uzel, Randall J. Platt, Parijat Sengupta, Roger D. Kamm, and Rashid BashirPNAS March 29, 2016 113 (13) 3497-3502; first published March 14, 2016. https://doi.org/10.1073/pnas.1516139113
Biochemistry
- You have accessStability of the human polymerase δ holoenzyme and its implications in lagging strand DNA synthesisMark Hedglin, Binod Pandey, and Stephen J. BenkovicPNAS March 29, 2016 113 (13) E1777-E1786; first published March 14, 2016. https://doi.org/10.1073/pnas.1523653113
- You have accessOpen complex scrunching before nucleotide addition accounts for the unusual transcription start site of E. coli ribosomal RNA promotersJared T. Winkelman, Pete Chandrangsu, Wilma Ross, and Richard L. GoursePNAS March 29, 2016 113 (13) E1787-E1795; first published March 14, 2016. https://doi.org/10.1073/pnas.1522159113
- Open AccessAcetyl-CoA carboxylase inhibition by ND-630 reduces hepatic steatosis, improves insulin sensitivity, and modulates dyslipidemia in ratsGeraldine Harriman, Jeremy Greenwood, Sathesh Bhat, Xinyi Huang, Ruiying Wang, Debamita Paul, Liang Tong, Asish K. Saha, William F. Westlin, Rosana Kapeller, and H. James Harwood Jr.PNAS March 29, 2016 113 (13) E1796-E1805; first published March 14, 2016. https://doi.org/10.1073/pnas.1520686113
- Open AccessAurone synthase is a catechol oxidase with hydroxylase activity and provides insights into the mechanism of plant polyphenol oxidasesChristian Molitor, Stephan Gerhard Mauracher, and Annette RompelPNAS March 29, 2016 113 (13) E1806-E1815; first published March 14, 2016. https://doi.org/10.1073/pnas.1523575113
- Open AccessTFE and Spt4/5 open and close the RNA polymerase clamp during the transcription cycleSarah Schulz, Andreas Gietl, Katherine Smollett, Philip Tinnefeld, Finn Werner, and Dina GrohmannPNAS March 29, 2016 113 (13) E1816-E1825; first published March 15, 2016. https://doi.org/10.1073/pnas.1515817113
- You have accessInositol hexakisphosphate (IP6) generated by IP5K mediates cullin-COP9 signalosome interactions and CRL functionPaul C. Scherer, Yan Ding, Zhiqing Liu, Jing Xu, Haibin Mao, James C. Barrow, Ning Wei, Ning Zheng, Solomon H. Snyder, and Feng RaoPNAS March 29, 2016 113 (13) 3503-3508; first published March 14, 2016. https://doi.org/10.1073/pnas.1525580113
- You have accessMolecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivativesHanno Sjuts, Attilio V. Vargiu, Steven M. Kwasny, Son T. Nguyen, Hong-Suk Kim, Xiaoyuan Ding, Alina R. Ornik, Paolo Ruggerone, Terry L. Bowlin, Hiroshi Nikaido, Klaas M. Pos, and Timothy J. OppermanPNAS March 29, 2016 113 (13) 3509-3514; first published March 14, 2016. https://doi.org/10.1073/pnas.1602472113
- Open AccessBRCA2 regulates DMC1-mediated recombination through the BRC repeatsJuan S. Martinez, Catharina von Nicolai, Taeho Kim, Åsa Ehlén, Alexander V. Mazin, Stephen C. Kowalczykowski, and Aura CarreiraPNAS March 29, 2016 113 (13) 3515-3520; first published March 14, 2016. https://doi.org/10.1073/pnas.1601691113
- You have accessBiosynthetic investigation of phomopsins reveals a widespread pathway for ribosomal natural products in AscomycetesWei Ding, Wan-Qiu Liu, Youli Jia, Yongzhen Li, Wilfred A. van der Donk, and Qi ZhangPNAS March 29, 2016 113 (13) 3521-3526; first published March 15, 2016. https://doi.org/10.1073/pnas.1522907113
- Open AccessInhibition of SCF ubiquitin ligases by engineered ubiquitin variants that target the Cul1 binding site on the Skp1–F-box interfaceMaryna Gorelik, Stephen Orlicky, Maria A. Sartori, Xiaojing Tang, Edyta Marcon, Igor Kurinov, Jack F. Greenblatt, Mike Tyers, Jason Moffat, Frank Sicheri, and Sachdev S. SidhuPNAS March 29, 2016 113 (13) 3527-3532; first published March 14, 2016. https://doi.org/10.1073/pnas.1519389113
Biophysics and Computational Biology
- You have accessIdentification of tissue-specific cell death using methylation patterns of circulating DNARoni Lehmann-Werman, Daniel Neiman, Hai Zemmour, Joshua Moss, Judith Magenheim, Adi Vaknin-Dembinsky, Sten Rubertsson, Bengt Nellgård, Kaj Blennow, Henrik Zetterberg, Kirsty Spalding, Michael J. Haller, Clive H. Wasserfall, Desmond A. Schatz, Carla J. Greenbaum, Craig Dorrell, Markus Grompe, Aviad Zick, Ayala Hubert, Myriam Maoz, Volker Fendrich, Detlef K. Bartsch, Talia Golan, Shmuel A. Ben Sasson, Gideon Zamir, Aharon Razin, Howard Cedar, A. M. James Shapiro, Benjamin Glaser, Ruth Shemer, and Yuval DorPNAS March 29, 2016 113 (13) E1826-E1834; first published March 14, 2016. https://doi.org/10.1073/pnas.1519286113
- Open AccessIdentifying genetic modulators of the connectivity between transcription factors and their transcriptional targetsMina Fazlollahi, Ivor Muroff, Eunjee Lee, Helen C. Causton, and Harmen J. BussemakerPNAS March 29, 2016 113 (13) E1835-E1843; first published March 10, 2016. https://doi.org/10.1073/pnas.1517140113
- Open AccessForce-producing ADP state of myosin bound to actinSarah F. Wulf, Virginie Ropars, Setsuko Fujita-Becker, Marco Oster, Goetz Hofhaus, Leonardo G. Trabuco, Olena Pylypenko, H. Lee Sweeney, Anne M. Houdusse, and Rasmus R. SchröderPNAS March 29, 2016 113 (13) E1844-E1852; first published March 14, 2016. https://doi.org/10.1073/pnas.1516598113
- You have accessRecognition of the disordered p53 transactivation domain by the transcriptional adapter zinc finger domains of CREB-binding proteinAlexander S. Krois, Josephine C. Ferreon, Maria A. Martinez-Yamout, H. Jane Dyson, and Peter E. WrightPNAS March 29, 2016 113 (13) E1853-E1862; first published March 14, 2016. https://doi.org/10.1073/pnas.1602487113
- You have accessHierarchy and extremes in selections from pools of randomized proteinsSébastien Boyer, Dipanwita Biswas, Ananda Kumar Soshee, Natale Scaramozzino, Clément Nizak, and Olivier RivoirePNAS March 29, 2016 113 (13) 3482-3487; first published March 11, 2016. https://doi.org/10.1073/pnas.1517813113
- You have accessSnapshot of sequential SNARE assembling states between membranes shows that N-terminal transient assembly initializes fusionYong Jian Wang, Feng Li, Nicolas Rodriguez, Xavier Lafosse, Christine Gourier, Eric Perez, and Frederic PincetPNAS March 29, 2016 113 (13) 3533-3538; first published March 15, 2016. https://doi.org/10.1073/pnas.1518935113
- Open AccessIntramolecular allosteric communication in dopamine D2 receptor revealed by evolutionary amino acid covariationYun-Min Sung, Angela D. Wilkins, Gustavo J. Rodriguez, Theodore G. Wensel, and Olivier LichtargePNAS March 29, 2016 113 (13) 3539-3544; first published March 15, 2016. https://doi.org/10.1073/pnas.1516579113
Cell Biology
- You have accessA RhoA and Rnd3 cycle regulates actin reassembly during membrane blebbingKana Aoki, Fumiyo Maeda, Tomoya Nagasako, Yuki Mochizuki, Seiichi Uchida, and Junichi IkenouchiPNAS March 29, 2016 113 (13) E1863-E1871; first published March 14, 2016. https://doi.org/10.1073/pnas.1600968113
- You have accessMitochondrial calcium uniporter regulator 1 (MCUR1) regulates the calcium threshold for the mitochondrial permeability transitionDipayan Chaudhuri, Daniel J. Artiga, Sunday A. Abiria, and David E. ClaphamPNAS March 29, 2016 113 (13) E1872-E1880; first published March 14, 2016. https://doi.org/10.1073/pnas.1602264113
- Open AccessRe-evaluation of the roles of DROSHA, Exportin 5, and DICER in microRNA biogenesisYoung-Kook Kim, Boseon Kim, and V. Narry KimPNAS March 29, 2016 113 (13) E1881-E1889; first published March 14, 2016. https://doi.org/10.1073/pnas.1602532113
Developmental Biology
- You have accessSp5 and Sp8 recruit β-catenin and Tcf1-Lef1 to select enhancers to activate Wnt target gene transcriptionMark W. Kennedy, Ravindra B. Chalamalasetty, Sara Thomas, Robert J. Garriock, Parthav Jailwala, and Terry P. YamaguchiPNAS March 29, 2016 113 (13) 3545-3550; first published March 11, 2016. https://doi.org/10.1073/pnas.1519994113
Ecology
- You have accessDiscovery of fairy circles in Australia supports self-organization theoryStephan Getzin, Hezi Yizhaq, Bronwyn Bell, Todd E. Erickson, Anthony C. Postle, Itzhak Katra, Omer Tzuk, Yuval R. Zelnik, Kerstin Wiegand, Thorsten Wiegand, and Ehud MeronPNAS March 29, 2016 113 (13) 3551-3556; first published March 14, 2016. https://doi.org/10.1073/pnas.1522130113
See companion article:
- Fairy circles develop without termitaria- Sep 01, 2016
- You have accessBiotic homogenization can decrease landscape-scale forest multifunctionalityFons van der Plas, Pete Manning, Santiago Soliveres, Eric Allan, Michael Scherer-Lorenzen, Kris Verheyen, Christian Wirth, Miguel A. Zavala, Evy Ampoorter, Lander Baeten, Luc Barbaro, Jürgen Bauhus, Raquel Benavides, Adam Benneter, Damien Bonal, Olivier Bouriaud, Helge Bruelheide, Filippo Bussotti, Monique Carnol, Bastien Castagneyrol, Yohan Charbonnier, David Anthony Coomes, Andrea Coppi, Cristina C. Bastias, Seid Muhie Dawud, Hans De Wandeler, Timo Domisch, Leena Finér, Arthur Gessler, André Granier, Charlotte Grossiord, Virginie Guyot, Stephan Hättenschwiler, Hervé Jactel, Bogdan Jaroszewicz, François-xavier Joly, Tommaso Jucker, Julia Koricheva, Harriet Milligan, Sandra Mueller, Bart Muys, Diem Nguyen, Martina Pollastrini, Sophia Ratcliffe, Karsten Raulund-Rasmussen, Federico Selvi, Jan Stenlid, Fernando Valladares, Lars Vesterdal, Dawid Zielínski, and Markus FischerPNAS March 29, 2016 113 (13) 3557-3562; first published March 15, 2016. https://doi.org/10.1073/pnas.1517903113
- Open AccessConservation triage or injurious neglect in endangered species recoveryLeah R. GerberPNAS March 29, 2016 113 (13) 3563-3566; first published March 14, 2016. https://doi.org/10.1073/pnas.1525085113
Evolution
- You have accessNew tyrannosaur from the mid-Cretaceous of Uzbekistan clarifies evolution of giant body sizes and advanced senses in tyrant dinosaursStephen L. Brusatte, Alexander Averianov, Hans-Dieter Sues, Amy Muir, and Ian B. ButlerPNAS March 29, 2016 113 (13) 3447-3452; first published March 14, 2016. https://doi.org/10.1073/pnas.1600140113
- You have accessSmall genome of the fungus Escovopsis weberi, a specialized disease agent of ant agricultureTom J. B. de Man, Jason E. Stajich, Christian P. Kubicek, Clotilde Teiling, Komal Chenthamara, Lea Atanasova, Irina S. Druzhinina, Natasha Levenkova, Stephanie S. L. Birnbaum, Seth M. Barribeau, Brooke A. Bozick, Garret Suen, Cameron R. Currie, and Nicole M. GerardoPNAS March 29, 2016 113 (13) 3567-3572; first published March 14, 2016. https://doi.org/10.1073/pnas.1518501113
- You have accessAutocratic strategies for iterated games with arbitrary action spacesAlex McAvoy and Christoph HauertPNAS March 29, 2016 113 (13) 3573-3578; first published March 14, 2016. https://doi.org/10.1073/pnas.1520163113
- Open AccessProtein networks identify novel symbiogenetic genes resulting from plastid endosymbiosis
- From the Cover
Raphaël Méheust, Ehud Zelzion, Debashish Bhattacharya, Philippe Lopez, and Eric BaptestePNAS March 29, 2016 113 (13) 3579-3584; first published March 14, 2016. https://doi.org/10.1073/pnas.1517551113 - Open AccessInbreeding depression across the lifespan in a wild mammal populationJisca Huisman, Loeske E. B. Kruuk, Philip A. Ellis, Tim Clutton-Brock, and Josephine M. PembertonPNAS March 29, 2016 113 (13) 3585-3590; first published March 15, 2016. https://doi.org/10.1073/pnas.1518046113
Genetics
- You have accessReevaluation of whether a soma–to–germ-line transformation extends lifespan in Caenorhabditis elegansAndrew Kekūpa'a Knutson, Andreas Rechtsteiner, and Susan StromePNAS March 29, 2016 113 (13) 3591-3596; first published March 14, 2016. https://doi.org/10.1073/pnas.1523402113
Immunology and Inflammation
- You have accessDetection, phenotyping, and quantification of antigen-specific T cells using a peptide-MHC dodecamerJun Huang, Xun Zeng, Natalia Sigal, Peder J. Lund, Laura F. Su, Huang Huang, Yueh-hsiu Chien, and Mark M. DavisPNAS March 29, 2016 113 (13) E1890-E1897; first published March 15, 2016. https://doi.org/10.1073/pnas.1602488113
Medical Sciences
- You have accessSoluble (pro)renin receptor via β-catenin enhances urine concentration capability as a target of liver X receptorXiaohan Lu, Fei Wang, Chuanming Xu, Sunny Soodvilai, Kexin Peng, Jiahui Su, Long Zhao, Kevin T. Yang, Yumei Feng, Shu-Feng Zhou, Jan-Åke Gustafsson, and Tianxin YangPNAS March 29, 2016 113 (13) E1898-E1906; first published March 16, 2016. https://doi.org/10.1073/pnas.1602397113
- Open AccessDisrupted iron homeostasis causes dopaminergic neurodegeneration in mice
- Inaugural Article
Pavle Matak, Andrija Matak, Sarah Moustafa, Dipendra K. Aryal, Eric J. Benner, William Wetsel, and Nancy C. AndrewsPNAS March 29, 2016 113 (13) 3428-3435; first published February 29, 2016. https://doi.org/10.1073/pnas.1519473113See companion article:
- Fe-deficiency and Parkinson’s disease- Mar 16, 2016
See companion article:
- Profile of Nancy C. Andrews- Aug 10, 2016
- You have accessFunctional polymorphisms of macrophage migration inhibitory factor as predictors of morbidity and mortality of pneumococcal meningitisAthina Savva, Matthijs C. Brouwer, Thierry Roger, Mercedes Valls Serón, Didier Le Roy, Bart Ferwerda, Arie van der Ende, Pierre-Yves Bochud, Diederik van de Beek, and Thierry CalandraPNAS March 29, 2016 113 (13) 3597-3602; first published March 14, 2016. https://doi.org/10.1073/pnas.1520727113
- You have accessExploring the surfaceome of Ewing sarcoma identifies a new and unique therapeutic targetJennifer Town, Helio Pais, Sally Harrison, Lucy F. Stead, Carole Bataille, Wilawan Bunjobpol, Jing Zhang, and Terence H. RabbittsPNAS March 29, 2016 113 (13) 3603-3608; first published March 15, 2016. https://doi.org/10.1073/pnas.1521251113
- You have accessSpironolactone blocks Epstein–Barr virus production by inhibiting EBV SM protein functionDinesh Verma, Jacob Thompson, and Sankar SwaminathanPNAS March 29, 2016 113 (13) 3609-3614; first published March 14, 2016. https://doi.org/10.1073/pnas.1523686113
Microbiology
- You have accessViral serine palmitoyltransferase induces metabolic switch in sphingolipid biosynthesis and is required for infection of a marine algaCarmit Ziv, Sergey Malitsky, Alaa Othman, Shifra Ben-Dor, Yu Wei, Shuning Zheng, Asaph Aharoni, Thorsten Hornemann, and Assaf VardiPNAS March 29, 2016 113 (13) E1907-E1916; first published March 16, 2016. https://doi.org/10.1073/pnas.1523168113
- Open AccessDiverse high-torque bacterial flagellar motors assemble wider stator rings using a conserved protein scaffoldMorgan Beeby, Deborah A. Ribardo, Caitlin A. Brennan, Edward G. Ruby, Grant J. Jensen, and David R. HendrixsonPNAS March 29, 2016 113 (13) E1917-E1926; first published March 14, 2016. https://doi.org/10.1073/pnas.1518952113
- You have accessRecombinant thiopeptides containing noncanonical amino acidsXiaozhou Luo, Claudio Zambaldo, Tao Liu, Yuhan Zhang, Weimin Xuan, Chen Wang, Sean A. Reed, Peng-Yu Yang, Rongsheng E. Wang, Tsotne Javahishvili, Peter G. Schultz, and Travis S. YoungPNAS March 29, 2016 113 (13) 3615-3620; first published March 14, 2016. https://doi.org/10.1073/pnas.1602733113
- Open AccessHuman mesenchymal stromal cells reduce influenza A H5N1-associated acute lung injury in vitro and in vivoMichael C. W. Chan, Denise I. T. Kuok, Connie Y. H. Leung, Kenrie P. Y. Hui, Sophie A. Valkenburg, Eric H. Y. Lau, John M. Nicholls, Xiaohui Fang, Yi Guan, Jae W. Lee, Renee W. Y. Chan, Robert G. Webster, Michael A. Matthay, and J. S. Malik PeirisPNAS March 29, 2016 113 (13) 3621-3626; first published March 14, 2016. https://doi.org/10.1073/pnas.1601911113
- You have accessBacteroides fragilis type VI secretion systems use novel effector and immunity proteins to antagonize human gut Bacteroidales speciesMaria Chatzidaki-Livanis, Naama Geva-Zatorsky, and Laurie E. ComstockPNAS March 29, 2016 113 (13) 3627-3632; first published March 7, 2016. https://doi.org/10.1073/pnas.1522510113
- You have accessInsight into the flagella type III export revealed by the complex structure of the type III ATPase and its regulatorKatsumi Imada, Tohru Minamino, Yumiko Uchida, Miki Kinoshita, and Keiichi NambaPNAS March 29, 2016 113 (13) 3633-3638; first published March 16, 2016. https://doi.org/10.1073/pnas.1524025113
- Open AccessHuman symbionts inject and neutralize antibacterial toxins to persist in the gutAaron G. Wexler, Yiqiao Bao, John C. Whitney, Louis-Marie Bobay, Joao B. Xavier, Whitman B. Schofield, Natasha A. Barry, Alistair B. Russell, Bao Q. Tran, Young Ah Goo, David R. Goodlett, Howard Ochman, Joseph D. Mougous, and Andrew L. GoodmanPNAS March 29, 2016 113 (13) 3639-3644; first published March 8, 2016. https://doi.org/10.1073/pnas.1525637113
Neuroscience
- You have accessPhasic, suprathreshold excitation and sustained inhibition underlie neuronal selectivity for short-duration soundsRishi K. Alluri, Gary J. Rose, Jessica L. Hanson, Christopher J. Leary, Gustavo A. Vasquez-Opazo, Jalina A. Graham, and Jeremy WilkersonPNAS March 29, 2016 113 (13) E1927-E1935; first published March 14, 2016. https://doi.org/10.1073/pnas.1520971113
- Open AccessFour-dimensional maps of the human somatosensory systemPietro Avanzini, Rouhollah O. Abdollahi, Ivana Sartori, Fausto Caruana, Veronica Pelliccia, Giuseppe Casaceli, Roberto Mai, Giorgio Lo Russo, Giacomo Rizzolatti, and Guy A. OrbanPNAS March 29, 2016 113 (13) E1936-E1943; first published March 14, 2016. https://doi.org/10.1073/pnas.1601889113
- You have accessNew inducible genetic method reveals critical roles of GABA in the control of feeding and metabolismFantao Meng, Yong Han, Dollada Srisai, Valery Belakhov, Monica Farias, Yong Xu, Richard D. Palmiter, Timor Baasov, and Qi WuPNAS March 29, 2016 113 (13) 3645-3650; first published March 14, 2016. https://doi.org/10.1073/pnas.1602049113
- Open AccessLSD1 modulates stress-evoked transcription of immediate early genes and emotional behaviorFrancesco Rusconi, Barbara Grillo, Luisa Ponzoni, Silvia Bassani, Emanuela Toffolo, Leda Paganini, Alessandra Mallei, Daniela Braida, Maria Passafaro, Maurizio Popoli, Mariaelvina Sala, and Elena BattaglioliPNAS March 29, 2016 113 (13) 3651-3656; first published March 14, 2016. https://doi.org/10.1073/pnas.1511974113
- Open AccessTemporally chimeric mice reveal flexibility of circadian period-setting in the suprachiasmatic nucleusNicola J. Smyllie, Johanna E. Chesham, Ryan Hamnett, Elizabeth S. Maywood, and Michael H. HastingsPNAS March 29, 2016 113 (13) 3657-3662; first published March 10, 2016. https://doi.org/10.1073/pnas.1511351113
Pharmacology
- Open AccessGene deficiency and pharmacological inhibition of soluble epoxide hydrolase confers resilience to repeated social defeat stressQian Ren, Min Ma, Tamaki Ishima, Christophe Morisseau, Jun Yang, Karen M. Wagner, Ji-chun Zhang, Chun Yang, Wei Yao, Chao Dong, Mei Han, Bruce D. Hammock, and Kenji HashimotoPNAS March 29, 2016 113 (13) E1944-E1952; first published March 14, 2016. https://doi.org/10.1073/pnas.1601532113
- You have accessTruncated mu opioid GPCR variant involvement in opioid-dependent and opioid-independent pain modulatory systems within the CNSGina F. Marrone, Steven G. Grinnell, Zhigang Lu, Grace C. Rossi, Valerie Le Rouzic, Jin Xu, Susruta Majumdar, Ying-Xian Pan, and Gavril W. PasternakPNAS March 29, 2016 113 (13) 3663-3668; first published March 14, 2016. https://doi.org/10.1073/pnas.1523894113
- Open AccessIdentification and characterization of influenza variants resistant to a viral endonuclease inhibitorMin-Suk Song, Gyanendra Kumar, William R. Shadrick, Wei Zhou, Trushar Jeevan, Zhenmei Li, P. Jake Slavish, Thomas P. Fabrizio, Sun-Woo Yoon, Thomas R. Webb, Richard J. Webby, and Stephen W. WhitePNAS March 29, 2016 113 (13) 3669-3674; first published March 14, 2016. https://doi.org/10.1073/pnas.1519772113
Physiology
- You have accessBiphasic regulation of InsP3 receptor gating by dual Ca2+ release channel BH3-like domains mediates Bcl-xL control of cell viabilityJun Yang, Horia Vais, Wenen Gu, and J. Kevin FoskettPNAS March 29, 2016 113 (13) E1953-E1962; first published March 14, 2016. https://doi.org/10.1073/pnas.1517935113
- You have accessSize and speed of the working stroke of cardiac myosin in situMarco Caremani, Francesca Pinzauti, Massimo Reconditi, Gabriella Piazzesi, Ger J. M. Stienen, Vincenzo Lombardi, and Marco LinariPNAS March 29, 2016 113 (13) 3675-3680; first published March 16, 2016. https://doi.org/10.1073/pnas.1525057113
Plant Biology
- You have accessCarnosic acid biosynthesis elucidated by a synthetic biology platformCodruta Ignea, Anastasia Athanasakoglou, Efstathia Ioannou, Panagiota Georgantea, Fotini A. Trikka, Sofia Loupassaki, Vassilios Roussis, Antonios M. Makris, and Sotirios C. KampranisPNAS March 29, 2016 113 (13) 3681-3686; first published March 14, 2016. https://doi.org/10.1073/pnas.1523787113
- Open AccessCytonuclear interactions affect adaptive traits of the annual plant Arabidopsis thaliana in the fieldFabrice Roux, Tristan Mary-Huard, Elise Barillot, Estelle Wenes, Lucy Botran, Stéphanie Durand, Romain Villoutreix, Marie-Laure Martin-Magniette, Christine Camilleri, and Françoise BudarPNAS March 29, 2016 113 (13) 3687-3692; first published March 15, 2016. https://doi.org/10.1073/pnas.1520687113
Psychological and Cognitive Sciences
- You have accessInability to suppress salient distractors predicts low visual working memory capacity
- From the Cover
John M. Gaspar, Gregory J. Christie, David J. Prime, Pierre Jolicœur, and John J. McDonaldPNAS March 29, 2016 113 (13) 3693-3698; first published February 22, 2016. https://doi.org/10.1073/pnas.1523471113See companion article:
- Tuning in by tuning out distractions- Mar 17, 2016
Corrections (Online Only)
- You have accessCorrection for Roberts et al., Continuity of mammalian fauna over the last 200,000 y in the Indian subcontinentPNAS March 29, 2016 113 (13) E1963; first published March 21, 2016. https://doi.org/10.1073/pnas.1603262113
- You have accessCorrection for Rodrigues et al., Biophysical principles predict fitness landscapes of drug resistancePNAS March 29, 2016 113 (13) E1964; first published March 21, 2016. https://doi.org/10.1073/pnas.1603613113
Commentaries
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