Metabolic features of chronic fatigue syndrome

Robert K. Naviaux, Jane C. Naviaux, Kefeng Li, A. Taylor Bright, William A. Alaynick, Lin Wang, Asha Baxter, Neil Nathan, Wayne Anderson, and Eric Gordon
PNAS September 13, 2016 113 (37) E5472-E5480; published ahead of print August 29, 2016 https://doi.org/10.1073/pnas.1607571113

  1. Edited by Ronald W. Davis, Stanford University School of Medicine, Stanford, CA, and approved July 13, 2016 (received for review May 11, 2016)

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Article Information

vol. 113 no. 37 E5472-E5480
DOI: 
https://doi.org/10.1073/pnas.1607571113
PubMed: 
27573827
Published By: 
National Academy of Sciences
Print ISSN: 
0027-8424
Online ISSN: 
1091-6490
History: 
  • Published in issue September 13, 2016.
  • Published first August 29, 2016.
Copyright & Usage: 
Freely available online through the PNAS open access option.

Author Information

  1. Robert K. Naviauxa,b,c,d,1,
  2. Jane C. Naviauxa,e,
  3. Kefeng Lia,b,
  4. A. Taylor Brighta,b,
  5. William A. Alaynicka,b,
  6. Lin Wanga,b,
  7. Asha Baxterf,
  8. Neil Nathanf,2,
  9. Wayne Andersonf, and
  10. Eric Gordonf
  1. aThe Mitochondrial and Metabolic Disease Center, University of California, San Diego School of Medicine, San Diego, CA 92103-8467;
  2. bDepartment of Medicine, University of California, San Diego School of Medicine, San Diego, CA 92103-8467;
  3. cDepartment of Pediatrics, University of California, San Diego School of Medicine, San Diego, CA 92103-8467;
  4. dDepartment of Pathology, University of California, San Diego School of Medicine, San Diego, CA 92103-8467;
  5. eDepartment of Neurosciences, University of California, San Diego School of Medicine, San Diego, CA 92103-8467;
  6. fGordon Medical Associates, Santa Rosa, CA 95403

  1. Edited by Ronald W. Davis, Stanford University School of Medicine, Stanford, CA, and approved July 13, 2016 (received for review May 11, 2016)

Footnotes

  • ↵1To whom correspondence should be addressed. Email: rnaviaux{at}ucsd.edu.

  • ↵2Present address: Redwood Valley Clinic, 8501 West Road, Redwood Valley, CA, 95470.

  • Author contributions: R.K.N., N.N., W.A., and E.G. designed research; R.K.N., J.C.N., K.L., A.T.B., L.W., A.B., N.N., W.A., and E.G. performed research; R.K.N., J.C.N., K.L., A.T.B., W.A.A., and L.W. contributed new reagents/analytic tools; R.K.N. wrote and managed the human subjects protocol; J.C.N. recruited subjects and developed methods; K.L. developed methods; A.T.B. created the pathway database and developed new bioinformatic methods; W.A.A. prepared the Cytoscape pathway visualizations; A.B. coordinated patient recruitment, medical histories, and clinical data; N.N., W.A., and E.G. identified and recruited patients; R.K.N., J.C.N., K.L., A.T.B., N.N., and E.G. analyzed data; and R.K.N., J.C.N., K.L., A.T.B., and W.A.A. wrote the paper.

  • The authors declare no conflict of interest.

  • This article is a PNAS Direct Submission.

  • Data deposition: The data reported in this paper have been deposited in the NIH Metabolomics Data Repository and Coordinating Center (DRCC) (accession no. ST000450).

  • This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1607571113/-/DCSupplemental.

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Article usage: August 2016 to February 2019

AbstractFullPdf
Aug 20167954280724851
Sep 201619638213885264
Oct 2016626363931540
Nov 201634263723941
Dec 201615342886686
Total 2016388156246213282
Jan 201714753022956
Feb 201713592676811
Mar 201710782112656
Apr 201713271713489
May 201711381708429
Jun 201710562477384
Jul 20179701441276
Aug 201714711305320
Sep 20178681854385
Oct 20176241196285
Nov 20174891601355
Dec 20174191296394
Total 201712274224015740
Jan 20186111727388
Feb 20189471333269
Mar 201813731836251
Apr 20188181671184
May 201813081957186
Jun 20188911436129
Jul 20187911095168
Aug 201811121541162
Sep 201815001787231
Oct 20181551220245
Nov 2018471180208
Dec 2018491185147
Total 20189602179682568
Jan 2019751450238
Feb 201988784372
Total 20191632234610
Total6085410506522200
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Metabolic features of chronic fatigue syndrome
Robert K. Naviaux, Jane C. Naviaux, Kefeng Li, A. Taylor Bright, William A. Alaynick, Lin Wang, Asha Baxter, Neil Nathan, Wayne Anderson, Eric Gordon
Proceedings of the National Academy of Sciences Sep 2016, 113 (37) E5472-E5480; DOI: 10.1073/pnas.1607571113
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