Table of Contents

Biological Sciences

• Anthropology

  • You have access

    Regional asynchronicity in dairy production and processing in early farming communities of the northern Mediterranean

    Cynthianne Debono Spiteri, Rosalind E. Gillis, Mélanie Roffet-Salque, Laura Castells Navarro, Jean Guilaine, Claire Manen, Italo M. Muntoni, Maria Saña Segui, Dushka Urem-Kotsou, Helen L. Whelton, Oliver E. Craig, Jean-Denis Vigne, and Richard P. Evershed

    PNAS November 29, 2016 113 (48) 13594-13599; first published November 14, 2016. https://doi.org/10.1073/pnas.1607810113

• Biochemistry

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    Molecular mechanisms of substrate-controlled ring dynamics and substepping in a nucleic acid-dependent hexameric motor

    Nathan D. Thomsen, Michael R. Lawson, Lea B. Witkowsky, Song Qu, and James M. Berger

    PNAS November 29, 2016 113 (48) E7691-E7700; first published November 16, 2016. https://doi.org/10.1073/pnas.1616745113

    See companion article:

    • Substrate loading control in a hexameric helicase

      - Nov 07, 2016
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    Ligand-induced and small-molecule control of substrate loading in a hexameric helicase

    Michael R. Lawson, Kevin Dyer, and James M. Berger

    PNAS November 29, 2016 113 (48) 13714-13719; first published November 7, 2016. https://doi.org/10.1073/pnas.1616749113

    See companion article:

    • Ring dynamics and substepping in a hexameric motor

      - Nov 16, 2016
  • You have access

    Tetraphenylethene-based highly emissive metallacage as a component of theranostic supramolecular nanoparticles

    Guocan Yu, Timothy R. Cook, Yang Li, Xuzhou Yan, Dan Wu, Li Shao, Jie Shen, Guping Tang, Feihe Huang, Xiaoyuan Chen, and Peter J. Stang

    PNAS November 29, 2016 113 (48) 13720-13725; first published November 15, 2016. https://doi.org/10.1073/pnas.1616836113
  • Open Access

    Structural basis of N-Myc binding by Aurora-A and its destabilization by kinase inhibitors

    Mark W. Richards, Selena G. Burgess, Evon Poon, Anne Carstensen, Martin Eilers, Louis Chesler, and Richard Bayliss

    PNAS November 29, 2016 113 (48) 13726-13731; first published November 11, 2016. https://doi.org/10.1073/pnas.1610626113
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    Global transformation of erythrocyte properties via engagement of an SH2-like sequence in band 3

    Estela Puchulu-Campanella, Francesco M. Turrini, Yen-Hsing Li, and Philip S. Low

    PNAS November 29, 2016 113 (48) 13732-13737; first published November 15, 2016. https://doi.org/10.1073/pnas.1611904113
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    Topic modeling for untargeted substructure exploration in metabolomics

    Justin Johan Jozias van der Hooft, Joe Wandy, Michael P. Barrett, Karl E. V. Burgess, and Simon Rogers

    PNAS November 29, 2016 113 (48) 13738-13743; first published November 16, 2016. https://doi.org/10.1073/pnas.1608041113
  • Open Access

    Two proofreading steps amplify the accuracy of genetic code translation

    Ka-Weng Ieong, Ülkü Uzun, Maria Selmer, and Måns Ehrenberg

    PNAS November 29, 2016 113 (48) 13744-13749; first published November 11, 2016. https://doi.org/10.1073/pnas.1610917113
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    An HD domain phosphohydrolase active site tailored for oxetanocin-A biosynthesis

    Jennifer Bridwell-Rabb, Gyunghoon Kang, Aoshu Zhong, Hung-wen Liu, and Catherine L. Drennan

    PNAS November 29, 2016 113 (48) 13750-13755; first published November 14, 2016. https://doi.org/10.1073/pnas.1613610113
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    Neutron structures of the Helicobacter pylori 5′-methylthioadenosine nucleosidase highlight proton sharing and protonation states

    Michael T. Banco, Vidhi Mishra, Andreas Ostermann, Tobias E. Schrader, Gary B. Evans, Andrey Kovalevsky, and Donald R. Ronning

    PNAS November 29, 2016 113 (48) 13756-13761; first published November 16, 2016. https://doi.org/10.1073/pnas.1609718113

• Biophysics and Computational Biology

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    Predicting protein–ligand affinity with a random matrix framework

    Alpha A. Lee, Michael P. Brenner, and Lucy J. Colwell

    PNAS November 29, 2016 113 (48) 13564-13569; first published November 16, 2016. https://doi.org/10.1073/pnas.1611138113
  • Open Access

    Fluorine-19 NMR and computational quantification of isoflurane binding to the voltage-gated sodium channel NaChBac

    Monica N. Kinde, Vasyl Bondarenko, Daniele Granata, Weiming Bu, Kimberly C. Grasty, Patrick J. Loll, Vincenzo Carnevale, Michael L. Klein, Roderic G. Eckenhoff, Pei Tang, and Yan Xu

    PNAS November 29, 2016 113 (48) 13762-13767; first published November 15, 2016. https://doi.org/10.1073/pnas.1609939113
  • Open Access

    Global analysis of somatic structural genomic alterations and their impact on gene expression in diverse human cancers

    Babak Alaei-Mahabadi, Joydeep Bhadury, Joakim W. Karlsson, Jonas A. Nilsson, and Erik Larsson

    PNAS November 29, 2016 113 (48) 13768-13773; first published November 16, 2016. https://doi.org/10.1073/pnas.1606220113

• Cell Biology

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    Two familial ALS proteins function in prevention/repair of transcription-associated DNA damage

    Sarah J. Hill, Daniel A. Mordes, Lisa A. Cameron, Donna S. Neuberg, Serena Landini, Kevin Eggan, and David M. Livingston

    PNAS November 29, 2016 113 (48) E7701-E7709; first published November 14, 2016. https://doi.org/10.1073/pnas.1611673113
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    DNA polymerase ζ limits chromosomal damage and promotes cell survival following aflatoxin exposure

    Ying-Chih Lin, Nichole Owen, Irina G. Minko, Sabine S. Lange, Junya Tomida, Liang Li, Michael P. Stone, Richard D. Wood, Amanda K. McCullough, and R. Stephen Lloyd

    PNAS November 29, 2016 113 (48) 13774-13779; first published November 14, 2016. https://doi.org/10.1073/pnas.1609024113

• Developmental Biology

  • Open Access

    Notch1 controls development of the extravillous trophoblast lineage in the human placenta

    Sandra Haider, Gudrun Meinhardt, Leila Saleh, Christian Fiala, Jürgen Pollheimer, and Martin Knöfler

    PNAS November 29, 2016 113 (48) E7710-E7719; first published November 14, 2016. https://doi.org/10.1073/pnas.1612335113
  • Open Access

    Control of Hoxd gene transcription in the mammary bud by hijacking a preexisting regulatory landscape

    Ruben Schep, Anamaria Necsulea, Eddie Rodríguez-Carballo, Isabel Guerreiro, Guillaume Andrey, Thi Hanh Nguyen Huynh, Virginie Marcet, Jozsef Zákány, Denis Duboule, and Leonardo Beccari

    PNAS November 29, 2016 113 (48) E7720-E7729; first published November 15, 2016. https://doi.org/10.1073/pnas.1617141113

• Ecology

  • Open Access

    Predators catalyze an increase in chloroviruses by foraging on the symbiotic hosts of zoochlorellae

    John P. DeLong, Zeina Al-Ameeli, Garry Duncan, James L. Van Etten, and David D. Dunigan

    PNAS November 29, 2016 113 (48) 13780-13784; first published November 7, 2016. https://doi.org/10.1073/pnas.1613843113
  • Open Access

    Global patterns of kelp forest change over the past half-century

    Kira A. Krumhansl, Daniel K. Okamoto, Andrew Rassweiler, Mark Novak, John J. Bolton, Kyle C. Cavanaugh, Sean D. Connell, Craig R. Johnson, Brenda Konar, Scott D. Ling, Fiorenza Micheli, Kjell M. Norderhaug, Alejandro Pérez-Matus, Isabel Sousa-Pinto, Daniel C. Reed, Anne K. Salomon, Nick T. Shears, Thomas Wernberg, Robert J. Anderson, Nevell S. Barrett, Alejandro H. Buschmann, Mark H. Carr, Jennifer E. Caselle, Sandrine Derrien-Courtel, Graham J. Edgar, Matt Edwards, James A. Estes, Claire Goodwin, Michael C. Kenner, David J. Kushner, Frithjof E. Moy, Julia Nunn, Robert S. Steneck, Julio Vásquez, Jane Watson, Jon D. Witman, and Jarrett E. K. Byrnes

    PNAS November 29, 2016 113 (48) 13785-13790; first published November 14, 2016. https://doi.org/10.1073/pnas.1606102113
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    Long-term empirical evidence of ocean warming leading to tropicalization of fish communities, increased herbivory, and loss of kelp

    Adriana Vergés, Christopher Doropoulos, Hamish A. Malcolm, Mathew Skye, Marina Garcia-Pizá, Ezequiel M. Marzinelli, Alexandra H. Campbell, Enric Ballesteros, Andrew S. Hoey, Ana Vila-Concejo, Yves-Marie Bozec, and Peter D. Steinberg

    PNAS November 29, 2016 113 (48) 13791-13796; first published November 14, 2016. https://doi.org/10.1073/pnas.1610725113

• Environmental Sciences

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    Temperature response of soil respiration largely unaltered with experimental warming

    Joanna C. Carey, Jianwu Tang, Pamela H. Templer, Kevin D. Kroeger, Thomas W. Crowther, Andrew J. Burton, Jeffrey S. Dukes, Bridget Emmett, Serita D. Frey, Mary A. Heskel, Lifen Jiang, Megan B. Machmuller, Jacqueline Mohan, Anne Marie Panetta, Peter B. Reich, Sabine Reinsch, Xin Wang, Steven D. Allison, Chris Bamminger, Scott Bridgham, Scott L. Collins, Giovanbattista de Dato, William C. Eddy, Brian J. Enquist, Marc Estiarte, John Harte, Amanda Henderson, Bart R. Johnson, Klaus Steenberg Larsen, Yiqi Luo, Sven Marhan, Jerry M. Melillo, Josep Peñuelas, Laurel Pfeifer-Meister, Christian Poll, Edward Rastetter, Andrew B. Reinmann, Lorien L. Reynolds, Inger K. Schmidt, Gaius R. Shaver, Aaron L. Strong, Vidya Suseela, and Albert Tietema

    PNAS November 29, 2016 113 (48) 13797-13802; first published November 14, 2016. https://doi.org/10.1073/pnas.1605365113

• Evolution

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    Origins of the current seventh cholera pandemic

    Dalong Hu, Bin Liu, Lu Feng, Peng Ding, Xi Guo, Min Wang, Boyang Cao, Peter R. Reeves, and Lei Wang

    PNAS November 29, 2016 113 (48) E7730-E7739; first published November 14, 2016. https://doi.org/10.1073/pnas.1608732113
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    Evolution of directional hearing in moths via conversion of bat detection devices to asymmetric pressure gradient receivers

    Andrew Reid, Thibaut Marin-Cudraz, James F. C. Windmill, and Michael D. Greenfield

    PNAS November 29, 2016 113 (48) E7740-E7748; first published November 14, 2016. https://doi.org/10.1073/pnas.1615691113
  • Open Access

    Sibling conflict and dishonest signaling in birds

    • From the Cover

    Shana M. Caro, Stuart A. West, and Ashleigh S. Griffin

    PNAS November 29, 2016 113 (48) 13803-13808; first published November 7, 2016. https://doi.org/10.1073/pnas.1606378113

    See companion article:

    • Begging, bragging, and deceit

      - Nov 21, 2016

• Genetics

  • Open Access

    Transposon mutagenesis identifies genes that cooperate with mutant Pten in breast cancer progression

    Roberto Rangel, Song-Choon Lee, Kenneth Hon-Kim Ban, Liliana Guzman-Rojas, Michael B. Mann, Justin Y. Newberg, Takahiro Kodama, Leslie A. McNoe, Luxmanan Selvanesan, Jerrold M. Ward, Alistair G. Rust, Kuan-Yew Chin, Michael A. Black, Nancy A. Jenkins, and Neal G. Copeland

    PNAS November 29, 2016 113 (48) E7749-E7758; first published November 14, 2016. https://doi.org/10.1073/pnas.1613859113
  • Open Access

    Multiple mechanisms contribute to double-strand break repair at rereplication forks in Drosophila follicle cells

    Jessica L. Alexander, Kelly Beagan, Terry L. Orr-Weaver, and Mitch McVey

    PNAS November 29, 2016 113 (48) 13809-13814; first published November 14, 2016. https://doi.org/10.1073/pnas.1617110113
  • Open Access

    Duplication of chicken defensin7 gene generated by gene conversion and homologous recombination

    Mi Ok Lee, Susanne Bornelöv, Leif Andersson, Susan J. Lamont, Junfeng Chen, and James E. Womack

    PNAS November 29, 2016 113 (48) 13815-13820; first published November 14, 2016. https://doi.org/10.1073/pnas.1616948113

• Immunology and Inflammation

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    Density of immunogenic antigens does not explain the presence or absence of the T-cell–inflamed tumor microenvironment in melanoma

    Stefani Spranger, Jason J. Luke, Riyue Bao, Yuanyuan Zha, Kyle M. Hernandez, Yan Li, Alexander P. Gajewski, Jorge Andrade, and Thomas F. Gajewski

    PNAS November 29, 2016 113 (48) E7759-E7768; first published November 11, 2016. https://doi.org/10.1073/pnas.1609376113

    See companion article:

    • PD-1/PD-L, cytolytic activity, and mutational load

      - Nov 11, 2016
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    Association of PD-1/PD-L axis expression with cytolytic activity, mutational load, and prognosis in melanoma and other solid tumors

    Ludmila Danilova, Hao Wang, Joel Sunshine, Genevieve J. Kaunitz, Tricia R. Cottrell, Haiying Xu, Jessica Esandrio, Robert A. Anders, Leslie Cope, Drew M. Pardoll, Charles G. Drake, and Janis M. Taube

    PNAS November 29, 2016 113 (48) E7769-E7777; first published November 11, 2016. https://doi.org/10.1073/pnas.1607836113

    See companion article:

    • Antigen-density inflamed vs. noninflamed tumors

      - Nov 11, 2016
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    Trypanosoma brucei metabolite indolepyruvate decreases HIF-1α and glycolysis in macrophages as a mechanism of innate immune evasion

    Anne F. McGettrick, Sarah E. Corcoran, Paul J. G. Barry, Jennifer McFarland, Cécile Crès, Anne M. Curtis, Edward Franklin, Sinéad C. Corr, K. Hun Mok, Eoin P. Cummins, Cormac T. Taylor, Luke A. J. O’Neill, and Derek P. Nolan

    PNAS November 29, 2016 113 (48) E7778-E7787; first published November 15, 2016. https://doi.org/10.1073/pnas.1608221113
  • Open Access

    Tethered IL-15 augments antitumor activity and promotes a stem-cell memory subset in tumor-specific T cells

    Lenka V. Hurton, Harjeet Singh, Amer M. Najjar, Kirsten C. Switzer, Tiejuan Mi, Sourindra Maiti, Simon Olivares, Brian Rabinovich, Helen Huls, Marie-Andrée Forget, Vrushali Datar, Partow Kebriaei, Dean A. Lee, Richard E. Champlin, and Laurence J. N. Cooper

    PNAS November 29, 2016 113 (48) E7788-E7797; first published November 14, 2016. https://doi.org/10.1073/pnas.1610544113
  • Open Access

    In vivo amelioration of endogenous antitumor autoantibodies via low-dose P₄N through the LTA4H/activin A/BAFF pathway

    Yu-Ling Lin, Nu-Man Tsai, Cheng-Hao Hsieh, Shu-Yi Ho, Jung Chang, Hsin-Yi Wu, Ming-Hua Hsu, Chia-Ching Chang, Kuang-Wen Liao, Tiffany L. B. Jackson, David E. Mold, and Ru Chih C. Huang

    PNAS November 29, 2016 113 (48) E7798-E7807; first published November 17, 2016. https://doi.org/10.1073/pnas.1604752113
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    Mouse model for acute Epstein–Barr virus infection

    Tristan Wirtz, Timm Weber, Sven Kracker, Thomas Sommermann, Klaus Rajewsky, and Tomoharu Yasuda

    PNAS November 29, 2016 113 (48) 13821-13826; first published November 16, 2016. https://doi.org/10.1073/pnas.1616574113
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    Graft versus self (GvS) against T-cell autoantigens is a mechanism of graft–host interaction

    Nora Mirza, Manfred Zierhut, Andreas Korn, Antje Bornemann, Wichard Vogel, Barbara Schmid-Horch, Wolfgang A. Bethge, Stefan Stevanović, Helmut R. Salih, Lothar Kanz, Hans-Georg Rammensee, and Sebastian P. Haen

    PNAS November 29, 2016 113 (48) 13827-13832; first published November 10, 2016. https://doi.org/10.1073/pnas.1609118113
  • Open Access

    Gram-positive bacteria are held at a distance in the colon mucus by the lectin-like protein ZG16

    Joakim H. Bergström, George M. H. Birchenough, Gergely Katona, Bjoern O. Schroeder, André Schütte, Anna Ermund, Malin E. V. Johansson, and Gunnar C. Hansson

    PNAS November 29, 2016 113 (48) 13833-13838; first published November 14, 2016. https://doi.org/10.1073/pnas.1611400113

• Medical Sciences

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    Heparanase is required for activation and function of macrophages

    Lilach Gutter-Kapon, Dror Alishekevitz, Yuval Shaked, Jin-Ping Li, Ami Aronheim, Neta Ilan, and Israel Vlodavsky

    PNAS November 29, 2016 113 (48) E7808-E7817; first published November 14, 2016. https://doi.org/10.1073/pnas.1611380113
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    Controlling DNA–nanoparticle serum interactions

    Kyryl Zagorovsky, Leo Y. T. Chou, and Warren C. W. Chan

    PNAS November 29, 2016 113 (48) 13600-13605; first published November 16, 2016. https://doi.org/10.1073/pnas.1610028113
  • Open Access

    Disparities in influenza mortality and transmission related to sociodemographic factors within Chicago in the pandemic of 1918

    • From the Cover

    Kyra H. Grantz, Madhura S. Rane, Henrik Salje, Gregory E. Glass, Stephen E. Schachterle, and Derek A. T. Cummings

    PNAS November 29, 2016 113 (48) 13839-13844; first published November 21, 2016. https://doi.org/10.1073/pnas.1612838113

    See companion article:

    • 1918 pandemic flu and socioeconomic disparities

      - Nov 22, 2016

    See companion article:

    • Mechanisms of pandemic mortality disparities

      - Apr 06, 2017
  • Open Access

    Epipolymorphisms associated with the clinical outcome of autoimmune arthritis affect CD4⁺ T cell activation pathways

    Roberto Spreafico, Maura Rossetti, John W. Whitaker, Wei Wang, Daniel J. Lovell, and Salvatore Albani

    PNAS November 29, 2016 113 (48) 13845-13850; first published November 14, 2016. https://doi.org/10.1073/pnas.1524056113
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    Amyloid fibrils from the N-terminal prion protein fragment are infectious

    Jin-Kyu Choi, Ignazio Cali, Krystyna Surewicz, Qingzhong Kong, Pierluigi Gambetti, and Witold K. Surewicz

    PNAS November 29, 2016 113 (48) 13851-13856; first published November 14, 2016. https://doi.org/10.1073/pnas.1610716113
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    Nanoparticle engineered TRAIL-overexpressing adipose-derived stem cells target and eradicate glioblastoma via intracranial delivery

    Xinyi Jiang, Sergio Fitch, Christine Wang, Christy Wilson, Jianfeng Li, Gerald A. Grant, and Fan Yang

    PNAS November 29, 2016 113 (48) 13857-13862; first published November 14, 2016. https://doi.org/10.1073/pnas.1615396113

• Microbiology

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    Role of nucleotide-binding oligomerization domain 1 (NOD1) and its variants in human cytomegalovirus control in vitro and in vivo

    Yi-Hsin Fan, Sujayita Roy, Rupkatha Mukhopadhyay, Arun Kapoor, Priya Duggal, Genevieve L. Wojcik, Robert F. Pass, and Ravit Arav-Boger

    PNAS November 29, 2016 113 (48) E7818-E7827; first published November 16, 2016. https://doi.org/10.1073/pnas.1611711113
  • Open Access

    Yellow fever virus capsid protein is a potent suppressor of RNA silencing that binds double-stranded RNA

    Glady Hazitha Samuel, Michael R. Wiley, Atif Badawi, Zach N. Adelman, and Kevin M. Myles

    PNAS November 29, 2016 113 (48) 13863-13868; first published November 14, 2016. https://doi.org/10.1073/pnas.1600544113
  • Open Access

    Structural and functional analysis of an anchorless fibronectin-binding protein FBPS from Gram-positive bacterium Streptococcus suis

    Abednego Moki Musyoki, Zhongyu Shi, Chunling Xuan, Guangwen Lu, Jianxun Qi, Feng Gao, Beiwen Zheng, Qiangmin Zhang, Yan Li, Joel Haywood, Cuihua Liu, Jinghua Yan, Yi Shi, and George F. Gao

    PNAS November 29, 2016 113 (48) 13869-13874; first published November 10, 2016. https://doi.org/10.1073/pnas.1608406113
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    Plant nodulation inducers enhance horizontal gene transfer of Azorhizobium caulinodans symbiosis island

    Jun Ling, Hui Wang, Ping Wu, Tao Li, Yu Tang, Nawar Naseer, Huiming Zheng, Catherine Masson-Boivin, Zengtao Zhong, and Jun Zhu

    PNAS November 29, 2016 113 (48) 13875-13880; first published November 14, 2016. https://doi.org/10.1073/pnas.1615121113
  • Open Access

    Armed conflict and population displacement as drivers of the evolution and dispersal of Mycobacterium tuberculosis

    Vegard Eldholm, John H.-O. Pettersson, Ola B. Brynildsrud, Andrew Kitchen, Erik Michael Rasmussen, Troels Lillebaek, Janne O. Rønning, Valeriu Crudu, Anne Torunn Mengshoel, Nadia Debech, Kristian Alfsnes, Jon Bohlin, Caitlin S. Pepperell, and Francois Balloux

    PNAS November 29, 2016 113 (48) 13881-13886; first published November 21, 2016. https://doi.org/10.1073/pnas.1611283113
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    Genome-wide screen identifies host colonization determinants in a bacterial gut symbiont

    J. Elijah Powell, Sean P. Leonard, Waldan K. Kwong, Philipp Engel, and Nancy A. Moran

    PNAS November 29, 2016 113 (48) 13887-13892; first published November 14, 2016. https://doi.org/10.1073/pnas.1610856113

• Neuroscience

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    VEGF preconditioning leads to stem cell remodeling and attenuates age-related decay of adult hippocampal neurogenesis

    Tamar Licht, Gadiel Rothe, Tirzah Kreisel, Brachi Wolf, Ofra Benny, Alasdair G. Rooney, Charles ffrench-Constant, Grigori Enikolopov, and Eli Keshet

    PNAS November 29, 2016 113 (48) E7828-E7836; first published November 14, 2016. https://doi.org/10.1073/pnas.1609592113
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    Circadian rhythms identified in Caenorhabditis elegans by in vivo long-term monitoring of a bioluminescent reporter

    María Eugenia Goya, Andrés Romanowski, Carlos S. Caldart, Claire Y. Bénard, and Diego A. Golombek

    PNAS November 29, 2016 113 (48) E7837-E7845; first published November 14, 2016. https://doi.org/10.1073/pnas.1605769113
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    Endogenous central amygdala mu-opioid receptor signaling promotes sodium appetite in mice

    Craig M. Smith, Lesley L. Walker, Tanawan Leeboonngam, Michael J. McKinley, Derek A. Denton, and Andrew J. Lawrence

    PNAS November 29, 2016 113 (48) 13893-13898; first published November 14, 2016. https://doi.org/10.1073/pnas.1616664113
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    Spontaneous default network activity reflects behavioral variability independent of mind-wandering

    Aaron Kucyi, Michael Esterman, Clay S. Riley, and Eve M. Valera

    PNAS November 29, 2016 113 (48) 13899-13904; first published November 15, 2016. https://doi.org/10.1073/pnas.1611743113

    See companion article:

    • Fitting data to neural models of mind-wandering

      - Jul 13, 2017

• Physiology

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    Atomic determinants of BK channel activation by polyunsaturated fatty acids

    Yutao Tian, Marius Aursnes, Trond Vidar Hansen, Jørn Eivind Tungen, Jason D. Galpin, Lilia Leisle, Christopher A. Ahern, Rong Xu, Stefan H. Heinemann, and Toshinori Hoshi

    PNAS November 29, 2016 113 (48) 13905-13910; first published November 14, 2016. https://doi.org/10.1073/pnas.1615562113

• Plant Biology

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    Control of seed dormancy in Arabidopsis by a cis-acting noncoding antisense transcript

    Halina Fedak, Malgorzata Palusinska, Katarzyna Krzyczmonik, Lien Brzezniak, Ruslan Yatusevich, Zbigniew Pietras, Szymon Kaczanowski, and Szymon Swiezewski

    PNAS November 29, 2016 113 (48) E7846-E7855; first published November 15, 2016. https://doi.org/10.1073/pnas.1608827113
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    Standing genetic variation in a tissue-specific enhancer underlies selfing-syndrome evolution in Capsella

    • From the Cover

    Adrien Sicard, Christian Kappel, Young Wha Lee, Natalia Joanna Woźniak, Cindy Marona, John R. Stinchcombe, Stephen I. Wright, and Michael Lenhard

    PNAS November 29, 2016 113 (48) 13911-13916; first published November 14, 2016. https://doi.org/10.1073/pnas.1613394113
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    Arabidopsis thaliana GH3.5 acyl acid amido synthetase mediates metabolic crosstalk in auxin and salicylic acid homeostasis

    Corey S. Westfall, Ashley M. Sherp, Chloe Zubieta, Sophie Alvarez, Evelyn Schraft, Romain Marcellin, Loren Ramirez, and Joseph M. Jez

    PNAS November 29, 2016 113 (48) 13917-13922; first published November 14, 2016. https://doi.org/10.1073/pnas.1612635113

• Psychological and Cognitive Sciences

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    Statistics of natural reverberation enable perceptual separation of sound and space

    James Traer and Josh H. McDermott

    PNAS November 29, 2016 113 (48) E7856-E7865; first published November 10, 2016. https://doi.org/10.1073/pnas.1612524113
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    Cortical networks involved in visual awareness independent of visual attention

    Taylor W. Webb, Kajsa M. Igelström, Aaron Schurger, and Michael S. A. Graziano

    PNAS November 29, 2016 113 (48) 13923-13928; first published November 14, 2016. https://doi.org/10.1073/pnas.1611505113