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Cryo-EM structure of the replisome reveals multiple interactions coordinating DNA synthesis
Contributed by Charles C. Richardson, January 27, 2017 (sent for review December 7, 2016; reviewed by James M. Berger and Nicholas E. Dixon)

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Article Information
- Published in issue March 7, 2017.
- Published first February 21, 2017.
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- Previous version (February 21, 2017 - 10:14).
- You are viewing the most recent version of this article.
Author Information
- aDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115;
- bDepartment of Molecular Biology and Genetics, The Danish Research Institute of Translational Neuroscience, Aarhus University, 8000 Aarhus, Denmark
Contributed by Charles C. Richardson, January 27, 2017 (sent for review December 7, 2016; reviewed by James M. Berger and Nicholas E. Dixon)
Footnotes
- ↵1To whom correspondence may be addressed. Email: arek{at}hms.harvard.edu or ccr{at}hms.harvard.edu.
↵2Present address: Department of Structural Biology, Max Planck Institute of Biophysics, 60538 Frankfurt, Germany.
Author contributions: A.W.K. and C.C.R. designed research; A.W.K. performed research; A.W.K., A.M., P.M., and P.S. contributed new reagents/analytic tools; A.W.K. and C.C.R. analyzed data; and A.W.K. and C.C.R. wrote the paper.
Reviewers: J.M.B., Johns Hopkins University School of Medicine; and N.E.D., University of Wollongong.
The authors declare no conflict of interest.
Data deposition: The cryo-EM map of the replisome was deposited in the EM Data Bank, www.emdatabank.org (accession no. EMD-8565).
This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1701252114/-/DCSupplemental.
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