Proceedings of the National Academy of Sciences: 114 (11)

New Research In

March 14, 2017; vol. 114 no. 11

This Week in PNAS

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In This Issue
PNAS March 14, 2017 114 (11) 2783; https://doi.org/10.1073/iti1117114

News Feature

An in-depth look at trending science issues.

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News Feature: Code wars
Front Matter
Stephen Ornes

PNAS March 14, 2017 114 (11) 2784-2787; https://doi.org/10.1073/pnas.1702236114

Commentaries

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G-quadruplex–forming promoter sequences enable transcriptional activation in response to oxidative stress
Bogdan I. Fedeles

PNAS March 14, 2017 114 (11) 2788-2790; published ahead of print March 6, 2017. https://doi.org/10.1073/pnas.1701244114
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Understanding bias in DNA repair
Terence R. Strick and Nigel J. Savery

PNAS March 14, 2017 114 (11) 2791-2793; published ahead of print March 6, 2017. https://doi.org/10.1073/pnas.1701549114
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Tantalizing evidence for the glacial North Atlantic bottom water
Katsumi Matsumoto

PNAS March 14, 2017 114 (11) 2794-2796; published ahead of print March 6, 2017. https://doi.org/10.1073/pnas.1701563114

PNAS Plus Significance Statements

Brief statements written by the authors about the significance of their papers.

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PNAS Plus Significance Statements
PNAS March 14, 2017 114 (11) 2797-2800; https://doi.org/10.1073/pnas.ss11411

Physical Sciences

Applied Physical Sciences
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  Understanding band gaps of solids in generalized Kohn–Sham theory
  John P. Perdew, Weitao Yang, Kieron Burke, Zenghui Yang, Eberhard K. U. Gross, Matthias Scheffler, Gustavo E. Scuseria, Thomas M. Henderson, Igor Ying Zhang, Adrienn Ruzsinszky, Haowei Peng, Jianwei Sun, Egor Trushin, and Andreas Görling
  
  PNAS March 14, 2017 114 (11) 2801-2806; published ahead of print March 6, 2017. https://doi.org/10.1073/pnas.1621352114
- Open Access
  In vivo polymerization and manufacturing of wires and supercapacitors in plants
  From the Cover
  
  Eleni Stavrinidou, Roger Gabrielsson, K. Peter R. Nilsson, Sandeep Kumar Singh, Juan Felipe Franco-Gonzalez, Anton V. Volkov, Magnus P. Jonsson, Andrea Grimoldi, Mathias Elgland, Igor V. Zozoulenko, Daniel T. Simon, and Magnus Berggren
  
  PNAS March 14, 2017 114 (11) 2807-2812; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1616456114
- Open Access
  Emergence of communities and diversity in social networks
  Xiao Han, Shinan Cao, Zhesi Shen, Boyu Zhang, Wen-Xu Wang, Ross Cressman, and H. Eugene Stanley
  
  PNAS March 14, 2017 114 (11) 2887-2891; published ahead of print February 24, 2017. https://doi.org/10.1073/pnas.1608164114
Biophysics and Computational Biology
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  Bioinformatic analysis of riboswitch structures uncovers variant classes with altered ligand specificity
  Zasha Weinberg, James W. Nelson, Christina E. Lünse, Madeline E. Sherlock, and Ronald R. Breaker
  
  PNAS March 14, 2017 114 (11) E2077-E2085; published ahead of print March 6, 2017. https://doi.org/10.1073/pnas.1619581114
- Open Access
  Formation and size distribution of self-assembled vesicles
  Changjin Huang, David Quinn, Yoel Sadovsky, Subra Suresh, and K. Jimmy Hsia
  
  PNAS March 14, 2017 114 (11) 2910-2915; published ahead of print March 6, 2017. https://doi.org/10.1073/pnas.1702065114
Chemistry
- Open Access
  Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations
  Federica Moraca, Jussara Amato, Francesco Ortuso, Anna Artese, Bruno Pagano, Ettore Novellino, Stefano Alcaro, Michele Parrinello, and Vittorio Limongelli
  
  PNAS March 14, 2017 114 (11) E2136-E2145; published ahead of print February 23, 2017. https://doi.org/10.1073/pnas.1612627114
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  Mechanism and bottlenecks in strand photodissociation of split green fluorescent proteins (GFPs)
  Chi-Yun Lin, Johan Both, Keunbong Do, and Steven G. Boxer
  
  PNAS March 14, 2017 114 (11) E2146-E2155; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1618087114
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  Voltage-sensitive rhodol with enhanced two-photon brightness
  Rishikesh U. Kulkarni, Daniel J. Kramer, Narges Pourmandi, Kaveh Karbasi, Helen S. Bateup, and Evan W. Miller
  
  PNAS March 14, 2017 114 (11) 2813-2818; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1610791114
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  Previously unknown class of metalorganic compounds revealed in meteorites
  From the Cover
  
  Alexander Ruf, Basem Kanawati, Norbert Hertkorn, Qing-Zhu Yin, Franco Moritz, Mourad Harir, Marianna Lucio, Bernhard Michalke, Joshua Wimpenny, Svetlana Shilobreeva, Basil Bronsky, Vladimir Saraykin, Zelimir Gabelica, Régis D. Gougeon, Eric Quirico, Stefan Ralew, Tomasz Jakubowski, Henning Haack, Michael Gonsior, Peter Jenniskens, Nancy W. Hinman, and Philippe Schmitt-Kopplin
  
  PNAS March 14, 2017 114 (11) 2819-2824; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1616019114
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  Electron transfer pathways in a multiheme cytochrome MtrF
  Hiroshi C. Watanabe, Yuki Yamashita, and Hiroshi Ishikita
  
  PNAS March 14, 2017 114 (11) 2916-2921; published ahead of print March 6, 2017. https://doi.org/10.1073/pnas.1617615114
Computer Sciences
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  Strategic aspects of cyberattack, attribution, and blame
  Benjamin Edwards, Alexander Furnas, Stephanie Forrest, and Robert Axelrod
  
  PNAS March 14, 2017 114 (11) 2825-2830; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1700442114
Earth, Atmospheric, and Planetary Sciences
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  Carbon isotope evidence for a northern source of deep water in the glacial western North Atlantic
  Lloyd D. Keigwin and Stephen A. Swift
  
  PNAS March 14, 2017 114 (11) 2831-2835; published ahead of print February 13, 2017. https://doi.org/10.1073/pnas.1614693114
Engineering
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  Tolerance to structural disorder and tunable mechanical behavior in self-assembled superlattices of polymer-grafted nanocrystals
  X. Wendy Gu, Xingchen Ye, David M. Koshy, Shraddha Vachhani, Peter Hosemann, and A. Paul Alivisatos
  
  PNAS March 14, 2017 114 (11) 2836-2841; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1618508114
Environmental Sciences
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  Enhanced groundwater recharge rates and altered recharge sensitivity to climate variability through subsurface heterogeneity
  Andreas Hartmann, Tom Gleeson, Yoshihide Wada, and Thorsten Wagener
  
  PNAS March 14, 2017 114 (11) 2842-2847; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1614941114
- Open Access
  Selenium deficiency risk predicted to increase under future climate change
  Gerrad D. Jones, Boris Droz, Peter Greve, Pia Gottschalk, Deyan Poffet, Steve P. McGrath, Sonia I. Seneviratne, Pete Smith, and Lenny H. E. Winkel
  
  PNAS March 14, 2017 114 (11) 2848-2853; published ahead of print February 21, 2017. https://doi.org/10.1073/pnas.1611576114
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  Co-occurrence of extremes in surface ozone, particulate matter, and temperature over eastern North America
  Jordan L. Schnell and Michael J. Prather
  
  PNAS March 14, 2017 114 (11) 2854-2859; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1614453114
Mathematics
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  Assessing significance in a Markov chain without mixing
  Maria Chikina, Alan Frieze, and Wesley Pegden
  
  PNAS March 14, 2017 114 (11) 2860-2864; published ahead of print February 28, 2017. https://doi.org/10.1073/pnas.1617540114
Physics
- Open Access
  Geometric localization of thermal fluctuations in red blood cells
  Arthur A. Evans, Basanta Bhaduri, Gabriel Popescu, and Alex J. Levine
  
  PNAS March 14, 2017 114 (11) 2865-2870; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1613204114
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  Shrinking instability of toroidal droplets
  Alexandros A. Fragkopoulos, Ekapop Pairam, Eric Berger, Phil N. Segre, and Alberto Fernández-Nieves
  
  PNAS March 14, 2017 114 (11) 2871-2875; published ahead of print March 1, 2017. https://doi.org/10.1073/pnas.1619073114

Political Sciences
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  Strategic aspects of cyberattack, attribution, and blame
  Benjamin Edwards, Alexander Furnas, Stephanie Forrest, and Robert Axelrod
  
  PNAS March 14, 2017 114 (11) 2825-2830; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1700442114
- You have access
  Assessing significance in a Markov chain without mixing
  Maria Chikina, Alan Frieze, and Wesley Pegden
  
  PNAS March 14, 2017 114 (11) 2860-2864; published ahead of print February 28, 2017. https://doi.org/10.1073/pnas.1617540114
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  Legislative coalitions with incomplete information
  Tiberiu Dragu and Michael Laver
  
  PNAS March 14, 2017 114 (11) 2876-2880; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1608514114
Psychological and Cognitive Sciences
- Open Access
  A neural model of valuation and information virality
  From the Cover
  
  Christin Scholz, Elisa C. Baek, Matthew Brook O’Donnell, Hyun Suk Kim, Joseph N. Cappella, and Emily B. Falk
  
  PNAS March 14, 2017 114 (11) 2881-2886; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1615259114
Social Sciences
- Open Access
  Emergence of communities and diversity in social networks
  Xiao Han, Shinan Cao, Zhesi Shen, Boyu Zhang, Wen-Xu Wang, Ross Cressman, and H. Eugene Stanley
  
  PNAS March 14, 2017 114 (11) 2887-2891; published ahead of print February 24, 2017. https://doi.org/10.1073/pnas.1608164114
Sustainability Science
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  Enhanced groundwater recharge rates and altered recharge sensitivity to climate variability through subsurface heterogeneity
  Andreas Hartmann, Tom Gleeson, Yoshihide Wada, and Thorsten Wagener
  
  PNAS March 14, 2017 114 (11) 2842-2847; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1614941114
- Open Access
  Human-started wildfires expand the fire niche across the United States
  From the Cover
  
  Jennifer K. Balch, Bethany A. Bradley, John T. Abatzoglou, R. Chelsea Nagy, Emily J. Fusco, and Adam L. Mahood
  
  PNAS March 14, 2017 114 (11) 2946-2951; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1617394114

Biological Sciences

Applied Biological Sciences
- Open Access
  Quantification of labile heme in live malaria parasites using a genetically encoded biosensor
  James R. Abshire, Christopher J. Rowlands, Suresh M. Ganesan, Peter T. C. So, and Jacquin C. Niles
  
  PNAS March 14, 2017 114 (11) E2068-E2076; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1615195114
Biochemistry
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  Bioinformatic analysis of riboswitch structures uncovers variant classes with altered ligand specificity
  Zasha Weinberg, James W. Nelson, Christina E. Lünse, Madeline E. Sherlock, and Ronald R. Breaker
  
  PNAS March 14, 2017 114 (11) E2077-E2085; published ahead of print March 6, 2017. https://doi.org/10.1073/pnas.1619581114
- Open Access
  Synergy of cAMP and calcium signaling pathways in CFTR regulation
  Zoltan Bozoky, Saumel Ahmadi, Tal Milman, Tae Hun Kim, Kai Du, Michelle Di Paola, Stan Pasyk, Roman Pekhletski, Jacob P. Keller, Christine E. Bear, and Julie D. Forman-Kay
  
  PNAS March 14, 2017 114 (11) E2086-E2095; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1613546114
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  Structural basis of autoregulatory scaffolding by apoptosis signal-regulating kinase 1
  Johannes F. Weijman, Abhishek Kumar, Sam A. Jamieson, Chontelle M. King, Tom T. Caradoc-Davies, Elizabeth C. Ledgerwood, James M. Murphy, and Peter D. Mace
  
  PNAS March 14, 2017 114 (11) E2096-E2105; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1620813114
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  Structure of human IFIT1 with capped RNA reveals adaptable mRNA binding and mechanisms for sensing N1 and N2 ribose 2′-O methylations
  Yazan M. Abbas, Beatrice Theres Laudenbach, Saúl Martínez-Montero, Regina Cencic, Matthias Habjan, Andreas Pichlmair, Masad J. Damha, Jerry Pelletier, and Bhushan Nagar
  
  PNAS March 14, 2017 114 (11) E2106-E2115; published ahead of print March 1, 2017. https://doi.org/10.1073/pnas.1612444114
- Open Access
  Genome-wide transcription-coupled repair in Escherichia coli is mediated by the Mfd translocase
  From the Cover
  
  Ogun Adebali, Yi-Ying Chiou, Jinchuan Hu, Aziz Sancar, and Christopher P. Selby
  
  PNAS March 14, 2017 114 (11) E2116-E2125; published ahead of print February 6, 2017. https://doi.org/10.1073/pnas.1700230114
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  Rps3/uS3 promotes mRNA binding at the 40S ribosome entry channel and stabilizes preinitiation complexes at start codons
  Jinsheng Dong, Colin Echeverría Aitken, Anil Thakur, Byung-Sik Shin, Jon R. Lorsch, and Alan G. Hinnebusch
  
  PNAS March 14, 2017 114 (11) E2126-E2135; published ahead of print February 21, 2017. https://doi.org/10.1073/pnas.1620569114
- You have access
  Voltage-sensitive rhodol with enhanced two-photon brightness
  Rishikesh U. Kulkarni, Daniel J. Kramer, Narges Pourmandi, Kaveh Karbasi, Helen S. Bateup, and Evan W. Miller
  
  PNAS March 14, 2017 114 (11) 2813-2818; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1610791114
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  Oligomeric lipoprotein PelC guides Pel polysaccharide export across the outer membrane of Pseudomonas aeruginosa
  Lindsey S. Marmont, Jacquelyn D. Rich, John C. Whitney, Gregory B. Whitfield, Henrik Almblad, Howard Robinson, Matthew R. Parsek, Joe J. Harrison, and P. Lynne Howell
  
  PNAS March 14, 2017 114 (11) 2892-2897; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1613606114
- Open Access
  Selection of DNA aptamers with two modified bases
  Bharat N. Gawande, John C. Rohloff, Jeffrey D. Carter, Ira von Carlowitz, Chi Zhang, Daniel J. Schneider, and Nebojsa Janjic
  
  PNAS March 14, 2017 114 (11) 2898-2903; published ahead of print March 6, 2017. https://doi.org/10.1073/pnas.1615475114
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  Specific phospholipid binding to Na,K-ATPase at two distinct sites
  Michael Habeck, Einat Kapri-Pardes, Michal Sharon, and Steven J. D. Karlish
  
  PNAS March 14, 2017 114 (11) 2904-2909; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1620799114
Biophysics and Computational Biology
- Open Access
  Ligand binding to telomeric G-quadruplex DNA investigated by funnel-metadynamics simulations
  Federica Moraca, Jussara Amato, Francesco Ortuso, Anna Artese, Bruno Pagano, Ettore Novellino, Stefano Alcaro, Michele Parrinello, and Vittorio Limongelli
  
  PNAS March 14, 2017 114 (11) E2136-E2145; published ahead of print February 23, 2017. https://doi.org/10.1073/pnas.1612627114
- You have access
  Mechanism and bottlenecks in strand photodissociation of split green fluorescent proteins (GFPs)
  Chi-Yun Lin, Johan Both, Keunbong Do, and Steven G. Boxer
  
  PNAS March 14, 2017 114 (11) E2146-E2155; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1618087114
- You have access
  Localization of the gate and selectivity filter of the full-length P2X7 receptor
  Anja Pippel, Michaela Stolz, Ronja Woltersdorf, Achim Kless, Günther Schmalzing, and Fritz Markwardt
  
  PNAS March 14, 2017 114 (11) E2156-E2165; published ahead of print February 24, 2017. https://doi.org/10.1073/pnas.1610414114
- Open Access
  Geometric localization of thermal fluctuations in red blood cells
  Arthur A. Evans, Basanta Bhaduri, Gabriel Popescu, and Alex J. Levine
  
  PNAS March 14, 2017 114 (11) 2865-2870; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1613204114
- Open Access
  Formation and size distribution of self-assembled vesicles
  Changjin Huang, David Quinn, Yoel Sadovsky, Subra Suresh, and K. Jimmy Hsia
  
  PNAS March 14, 2017 114 (11) 2910-2915; published ahead of print March 6, 2017. https://doi.org/10.1073/pnas.1702065114
- You have access
  Electron transfer pathways in a multiheme cytochrome MtrF
  Hiroshi C. Watanabe, Yuki Yamashita, and Hiroshi Ishikita
  
  PNAS March 14, 2017 114 (11) 2916-2921; published ahead of print March 6, 2017. https://doi.org/10.1073/pnas.1617615114
- You have access
  Spatial confinement of active microtubule networks induces large-scale rotational cytoplasmic flow
  Kazuya Suzuki, Makito Miyazaki, Jun Takagi, Takeshi Itabashi, and Shin’ichi Ishiwata
  
  PNAS March 14, 2017 114 (11) 2922-2927; published ahead of print March 6, 2017. https://doi.org/10.1073/pnas.1616001114
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  Knowledge-based entropies improve the identification of native protein structures
  Kannan Sankar, Kejue Jia, and Robert L. Jernigan
  
  PNAS March 14, 2017 114 (11) 2928-2933; published ahead of print March 6, 2017. https://doi.org/10.1073/pnas.1613331114
Cell Biology
- Open Access
  LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells
  Mingyu Gu, Dollie LaJoie, Opal S. Chen, Alexander von Appen, Mark S. Ladinsky, Michael J. Redd, Linda Nikolova, Pamela J. Bjorkman, Wesley I. Sundquist, Katharine S. Ullman, and Adam Frost
  
  PNAS March 14, 2017 114 (11) E2166-E2175; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1613916114
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  SM protein Munc18-2 facilitates transition of Syntaxin 11-mediated lipid mixing to complete fusion for T-lymphocyte cytotoxicity
  Waldo A. Spessott, Maria L. Sanmillan, Margaret E. McCormick, Vineet V. Kulkarni, and Claudio G. Giraudo
  
  PNAS March 14, 2017 114 (11) E2176-E2185; published ahead of print March 6, 2017. https://doi.org/10.1073/pnas.1617981114
- Open Access
  Vitamin D receptor regulates autophagy in the normal mammary gland and in luminal breast cancer cells
  Luz E. Tavera-Mendoza, Thomas Westerling, Eric Libby, Andriy Marusyk, Laura Cato, Raymundo Cassani, Lisa A. Cameron, Scott B. Ficarro, Jarrod A. Marto, Jelena Klawitter, and Myles Brown
  
  PNAS March 14, 2017 114 (11) E2186-E2194; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1615015114
- Open Access
  Metabolic origins of spatial organization in the tumor microenvironment
  Carlos Carmona-Fontaine, Maxime Deforet, Leila Akkari, Craig B. Thompson, Johanna A. Joyce, and Joao B. Xavier
  
  PNAS March 14, 2017 114 (11) 2934-2939; published ahead of print February 28, 2017. https://doi.org/10.1073/pnas.1700600114
Developmental Biology
- Open Access
  Aberrant splicing in maize rough endosperm3 reveals a conserved role for U12 splicing in eukaryotic multicellular development
  Christine M. Gault, Federico Martin, Wenbin Mei, Fang Bai, Joseph B. Black, W. Brad Barbazuk, and A. Mark Settles
  
  PNAS March 14, 2017 114 (11) E2195-E2204; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1616173114
Ecology
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  Microbial community assembly and evolution in subseafloor sediment
  Piotr Starnawski, Thomas Bataillon, Thijs J. G. Ettema, Lara M. Jochum, Lars Schreiber, Xihan Chen, Mark A. Lever, Martin F. Polz, Bo B. Jørgensen, Andreas Schramm, and Kasper U. Kjeldsen
  
  PNAS March 14, 2017 114 (11) 2940-2945; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1614190114
Environmental Sciences
- Open Access
  Human-started wildfires expand the fire niche across the United States
  From the Cover
  
  Jennifer K. Balch, Bethany A. Bradley, John T. Abatzoglou, R. Chelsea Nagy, Emily J. Fusco, and Adam L. Mahood
  
  PNAS March 14, 2017 114 (11) 2946-2951; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1617394114
Genetics
- Open Access
  Monoubiquitylation of histone H2B contributes to the bypass of DNA damage during and after DNA replication
  Shih-Hsun Hung, Ronald P. Wong, Helle D. Ulrich, and Cheng-Fu Kao
  
  PNAS March 14, 2017 114 (11) E2205-E2214; published ahead of print February 28, 2017. https://doi.org/10.1073/pnas.1612633114
- Open Access
  Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for stratification
  Liming Chen, Piroon Jenjaroenpun, Andrea Mun Ching Pillai, Anna V. Ivshina, Ghim Siong Ow, Motakis Efthimios, Tang Zhiqun, Tuan Zea Tan, Song-Choon Lee, Keith Rogers, Jerrold M. Ward, Seiichi Mori, David J. Adams, Nancy A. Jenkins, Neal G. Copeland, Kenneth Hon-Kim Ban, Vladimir A. Kuznetsov, and Jean Paul Thiery
  
  PNAS March 14, 2017 114 (11) E2215-E2224; published ahead of print March 1, 2017. https://doi.org/10.1073/pnas.1701512114
Immunology and Inflammation
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  BET N-terminal bromodomain inhibition selectively blocks Th17 cell differentiation and ameliorates colitis in mice
  Kalung Cheung, Geming Lu, Rajal Sharma, Adam Vincek, Ruihua Zhang, Alexander N. Plotnikov, Fan Zhang, Qiang Zhang, Ying Ju, Yuan Hu, Li Zhao, Xinye Han, Jamel Meslamani, Feihong Xu, Anbalagan Jaganathan, Tong Shen, Hongfa Zhu, Elena Rusinova, Lei Zeng, Jiachi Zhou, Jianjun Yang, Liang Peng, Michael Ohlmeyer, Martin J. Walsh, David Y. Zhang, Huabao Xiong, and Ming-Ming Zhou
  
  PNAS March 14, 2017 114 (11) 2952-2957; published ahead of print March 6, 2017. https://doi.org/10.1073/pnas.1615601114
Medical Sciences
- Open Access
  Permeation of macromolecules into the renal glomerular basement membrane and capture by the tubules
  Marlon G. Lawrence, Michael K. Altenburg, Ryan Sanford, Julian D. Willett, Benjamin Bleasdale, Byron Ballou, Jennifer Wilder, Feng Li, Jeffrey H. Miner, Ulla B. Berg, and Oliver Smithies
  
  PNAS March 14, 2017 114 (11) 2958-2963; published ahead of print February 28, 2017. https://doi.org/10.1073/pnas.1616457114
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  Receptor-interacting protein kinase 3 promotes platelet activation and thrombosis
  Yiwen Zhang, Jian Zhang, Rong Yan, Jingluan Tian, Yang Zhang, Jie Zhang, Mengxing Chen, Qingya Cui, Lili Zhao, Renping Hu, Miao Jiang, Zhenyu Li, Changgeng Ruan, Sudan He, and Kesheng Dai
  
  PNAS March 14, 2017 114 (11) 2964-2969; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1610963114
Microbiology
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  Glyoxylate detoxification is an essential function of malate synthase required for carbon assimilation in Mycobacterium tuberculosis
  Susan Puckett, Carolina Trujillo, Zhe Wang, Hyungjin Eoh, Thomas R. Ioerger, Inna Krieger, James Sacchettini, Dirk Schnappinger, Kyu Y. Rhee, and Sabine Ehrt
  
  PNAS March 14, 2017 114 (11) E2225-E2232; published ahead of print March 6, 2017. https://doi.org/10.1073/pnas.1617655114
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  Manganese scavenging and oxidative stress response mediated by type VI secretion system in Burkholderia thailandensis
  Meiru Si, Chao Zhao, Brianne Burkinshaw, Bing Zhang, Dawei Wei, Yao Wang, Tao G. Dong, and Xihui Shen
  
  PNAS March 14, 2017 114 (11) E2233-E2242; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1614902114
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  Cooperation of two distinct coupling proteins creates chemosensory network connections
  Samar Abedrabbo, Juan Castellon, Kieran D. Collins, Kevin S. Johnson, and Karen M. Ottemann
  
  PNAS March 14, 2017 114 (11) 2970-2975; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1618227114
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  Cas9-mediated genome editing in the methanogenic archaeon Methanosarcina acetivorans
  Dipti D. Nayak and William W. Metcalf
  
  PNAS March 14, 2017 114 (11) 2976-2981; published ahead of print March 6, 2017. https://doi.org/10.1073/pnas.1618596114
Neuroscience
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  Rapid and efficient generation of oligodendrocytes from human induced pluripotent stem cells using transcription factors
  Marc Ehrlich, Sabah Mozafari, Michael Glatza, Laura Starost, Sergiy Velychko, Anna-Lena Hallmann, Qiao-Ling Cui, Axel Schambach, Kee-Pyo Kim, Corinne Bachelin, Antoine Marteyn, Gunnar Hargus, Radia Marie Johnson, Jack Antel, Jared Sterneckert, Holm Zaehres, Hans R. Schöler, Anne Baron-Van Evercooren, and Tanja Kuhlmann
  
  PNAS March 14, 2017 114 (11) E2243-E2252; published ahead of print February 28, 2017. https://doi.org/10.1073/pnas.1614412114
- Open Access
  A neural model of valuation and information virality
  From the Cover
  
  Christin Scholz, Elisa C. Baek, Matthew Brook O’Donnell, Hyun Suk Kim, Joseph N. Cappella, and Emily B. Falk
  
  PNAS March 14, 2017 114 (11) 2881-2886; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1615259114
Pharmacology
- Open Access
  Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease
  Amy R. Dunn, Kristen A. Stout, Minagi Ozawa, Kelly M. Lohr, Carlie A. Hoffman, Alison I. Bernstein, Yingjie Li, Minzheng Wang, Carmelo Sgobio, Namratha Sastry, Huaibin Cai, W. Michael Caudle, and Gary W. Miller
  
  PNAS March 14, 2017 114 (11) E2253-E2262; published ahead of print February 28, 2017. https://doi.org/10.1073/pnas.1616892114
Plant Biology
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  Agrobacterium-delivered virulence protein VirE2 is trafficked inside host cells via a myosin XI-K–powered ER/actin network
  Qinghua Yang, Xiaoyang Li, Haitao Tu, and Shen Q. Pan
  
  PNAS March 14, 2017 114 (11) 2982-2987; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1612098114
- You have access
  Amino acid oxidation of the D1 and D2 proteins by oxygen radicals during photoinhibition of Photosystem II
  Ravindra Kale, Annette E. Hebert, Laurie K. Frankel, Larry Sallans, Terry M. Bricker, and Pavel Pospíšil
  
  PNAS March 14, 2017 114 (11) 2988-2993; published ahead of print March 6, 2017. https://doi.org/10.1073/pnas.1618922114

Corrections (Online Only)

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Correction for Shrivastava et al., Global long-range transport and lung cancer risk from polycyclic aromatic hydrocarbons shielded by coatings of organic aerosol
PNAS March 14, 2017 114 (11) E2263; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1702221114
You have access
Correction for Furuta et al., Measuring collective transport by defined numbers of processive and nonprocessive kinesin motors
PNAS March 14, 2017 114 (11) E2264; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1701954114
You have access
Correction for Tung et al., β-Catenin haploinsufficiency promotes mammary tumorigenesis in an ErbB2-positive basal breast cancer model
PNAS March 14, 2017 114 (11) E2265; published ahead of print February 27, 2017. https://doi.org/10.1073/pnas.1702117114

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