Researchers are exploring whether these ubiquitous fluorinated molecules might worsen infections or hamper vaccine effectiveness.
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The global architecture of bHLH–PAS heterodimers. From Left to Right, the structure of ARNT-containing complexes: AHR–ARNT bound to DNA encoding the DRE (PDB ID code 5V0L), NPAS3–ARNT bound to DNA encoding the HRE (PDB ID code 5SY7), and HIF1-α–ARNT bound to the HRE (PDB ID code HZPR). On the far right, the CLOCK–BMAL1 bHLH–PAS structure (PDB ID code 4F3L) is aligned to the bHLH domain of the CLOCK–BMAL1 bHLH–E-box DNA structure (PDB ID code 4H10).
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