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Full Text
June 27, 2017; vol. 114 no. 26
This Week in PNAS
Letters (Online Only)
- You have accessOrigin of magnetotaxis: Vertical inheritance or horizontal transfer?Sishuo Wang and Youhua ChenPNAS June 27, 2017 114 (26) E5016-E5018; first published June 12, 2017. https://doi.org/10.1073/pnas.1706937114
- You have accessReply to Wang and Chen: An ancient origin of magnetotactic bacteriaWei Lin, Greig A. Paterson, Qiyun Zhu, Yinzhao Wang, Evguenia Kopylova, Ying Li, Rob Knight, Dennis A. Bazylinski, Rixiang Zhu, Joseph L. Kirschvink, and Yongxin PanPNAS June 27, 2017 114 (26) E5019-E5020; first published June 12, 2017. https://doi.org/10.1073/pnas.1707301114
See companion article:
- Archean origin of magnetotactic bacteria- Feb 13, 2017
- You have accessThe United States can keep the grid stable at low cost with 100% clean, renewable energy in all sectors despite inaccurate claimsMark Z. Jacobson, Mark A. Delucchi, Mary A. Cameron, and Bethany A. FrewPNAS June 27, 2017 114 (26) E5021-E5023; first published June 19, 2017. https://doi.org/10.1073/pnas.1708069114
Science and Culture
How science intersects with culture.
- You have accessScience and Culture: Armed with a knack for patterns and symmetry, mathematical sculptors create compelling forms
- Front Matter
Stephen Ornes
Inner Workings
An over-the-shoulder look at scientists at work.
QnAs
- You have accessQnAs with Tony Hunter and James AllisonPrashant NairPNAS June 27, 2017 114 (26) 6649-6652; first published June 19, 2017. https://doi.org/10.1073/pnas.1707946114
PNAS Plus Significance Statements
Brief statements written by the authors about the significance of their papers.
Perspective
- You have accessInhibitory engrams in perception and memoryHelen C. Barron, Tim P. Vogels, Timothy E. Behrens, and Mani RamaswamiPNAS June 27, 2017 114 (26) 6666-6674; first published June 13, 2017. https://doi.org/10.1073/pnas.1701812114
Physical Sciences
Applied Mathematics
- Open AccessRandom subsets of structured deterministic frames have MANOVA spectraMarina Haikin, Ram Zamir, and Matan GavishPNAS June 27, 2017 114 (26) E5024-E5033; first published June 13, 2017. https://doi.org/10.1073/pnas.1700203114
- You have accessSynchrony affects Taylor’s law in theory and data
- From the Cover
Daniel C. Reuman, Lei Zhao, Lawrence W. Sheppard, Philip C. Reid, and Joel E. CohenPNAS June 27, 2017 114 (26) 6788-6793; first published May 30, 2017. https://doi.org/10.1073/pnas.1703593114See companion article:
- Unfinished synchrony- Jun 12, 2017
Applied Physical Sciences
- Open AccessCu metal embedded in oxidized matrix catalyst to promote CO2 activation and CO dimerization for electrochemical reduction of CO2Hai Xiao, William A. Goddard III, Tao Cheng, and Yuanyue LiuPNAS June 27, 2017 114 (26) 6685-6688; first published June 12, 2017. https://doi.org/10.1073/pnas.1702405114
Astronomy
- You have accessEnhanced interplanetary panspermia in the TRAPPIST-1 systemManasvi Lingam and Abraham LoebPNAS June 27, 2017 114 (26) 6689-6693; first published June 13, 2017. https://doi.org/10.1073/pnas.1703517114
Biophysics and Computational Biology
- Open AccessBroken flow symmetry explains the dynamics of small particles in deterministic lateral displacement arraysSung-Cheol Kim, Benjamin H. Wunsch, Huan Hu, Joshua T. Smith, Robert H. Austin, and Gustavo StolovitzkyPNAS June 27, 2017 114 (26) E5034-E5041; first published June 12, 2017. https://doi.org/10.1073/pnas.1706645114
- You have accessUbiquitin S65 phosphorylation engenders a pH-sensitive conformational switchXu Dong, Zhou Gong, Yun-Bi Lu, Kan Liu, Ling-Yun Qin, Meng-Lin Ran, Chang-Li Zhang, Zhu Liu, Wei-Ping Zhang, and Chun TangPNAS June 27, 2017 114 (26) 6770-6775; first published June 13, 2017. https://doi.org/10.1073/pnas.1705718114
- You have accessStructural studies of viperin, an antiviral radical SAM enzymeMichael K. Fenwick, Yue Li, Peter Cresswell, Yorgo Modis, and Steven E. EalickPNAS June 27, 2017 114 (26) 6806-6811; first published June 12, 2017. https://doi.org/10.1073/pnas.1705402114
- You have accessPharmacology of the Nav1.1 domain IV voltage sensor reveals coupling between inactivation gating processesJeremiah D. Osteen, Kevin Sampson, Vivek Iyer, David Julius, and Frank BosmansPNAS June 27, 2017 114 (26) 6836-6841; first published June 12, 2017. https://doi.org/10.1073/pnas.1621263114
Chemistry
- Open AccessCupriphication of gold to sensitize d10–d10 metal–metal bonds and near-unity phosphorescence quantum yieldsRossana Galassi, Mukunda M. Ghimire, Brooke M. Otten, Simone Ricci, Roy N. McDougald Jr., Ruaa M. Almotawa, Dieaa Alhmoud, Joshua F. Ivy, Abdel-Monem M. Rawashdeh, Vladimir N. Nesterov, Eric W. Reinheimer, Lee M. Daniels, Alfredo Burini, and Mohammad A. OmaryPNAS June 27, 2017 114 (26) E5042-E5051; first published June 14, 2017. https://doi.org/10.1073/pnas.1700890114
- You have accessPeripheral modifications of [Ψ[CH2NH]Tpg4]vancomycin with added synergistic mechanisms of action provide durable and potent antibiotics
- From the Cover
Akinori Okano, Nicholas A. Isley, and Dale L. BogerPNAS June 27, 2017 114 (26) E5052-E5061; first published May 30, 2017. https://doi.org/10.1073/pnas.1704125114See companion article:
- A victory in the battle against bacteria- Jun 12, 2017
- You have accessTrigger loop of RNA polymerase is a positional, not acid–base, catalyst for both transcription and proofreadingTatiana V. Mishanina, Michael Z. Palo, Dhananjaya Nayak, Rachel A. Mooney, and Robert LandickPNAS June 27, 2017 114 (26) E5103-E5112; first published June 12, 2017. https://doi.org/10.1073/pnas.1702383114
- You have accessAdaptor protein mediates dynamic pump assembly for bacterial metal effluxAce George Santiago, Tai-Yen Chen, Lauren A. Genova, Won Jung, Alayna M. George Thompson, Megan M. McEvoy, and Peng ChenPNAS June 27, 2017 114 (26) 6694-6699; first published June 12, 2017. https://doi.org/10.1073/pnas.1704729114
- You have accessIntraoperative assessment of tumor margins during glioma resection by desorption electrospray ionization-mass spectrometryValentina Pirro, Clint M. Alfaro, Alan K. Jarmusch, Eyas M. Hattab, Aaron A. Cohen-Gadol, and R. Graham CooksPNAS June 27, 2017 114 (26) 6700-6705; first published June 12, 2017. https://doi.org/10.1073/pnas.1706459114
- Open AccessSubsurface oxide plays a critical role in CO2 activation by Cu(111) surfaces to form chemisorbed CO2, the first step in reduction of CO2Marco Favaro, Hai Xiao, Tao Cheng, William A. Goddard III, Junko Yano, and Ethan J. CrumlinPNAS June 27, 2017 114 (26) 6706-6711; first published June 12, 2017. https://doi.org/10.1073/pnas.1701405114
Earth, Atmospheric, and Planetary Sciences
- Open AccessHow temporal patterns in rainfall determine the geomorphology and carbon fluxes of tropical peatlandsAlexander R. Cobb, Alison M. Hoyt, Laure Gandois, Jangarun Eri, René Dommain, Kamariah Abu Salim, Fuu Ming Kai, Nur Salihah Haji Su’ut, and Charles F. HarveyPNAS June 27, 2017 114 (26) E5187-E5196; first published June 12, 2017. https://doi.org/10.1073/pnas.1701090114
- You have accessAge of Jupiter inferred from the distinct genetics and formation times of meteorites
- From the Cover
Thomas S. Kruijer, Christoph Burkhardt, Gerrit Budde, and Thorsten KleinePNAS June 27, 2017 114 (26) 6712-6716; first published June 12, 2017. https://doi.org/10.1073/pnas.1704461114
Engineering
- You have accessAll-angle negative refraction of highly squeezed plasmon and phonon polaritons in graphene–boron nitride heterostructuresXiao Lin, Yi Yang, Nicholas Rivera, Josué J. López, Yichen Shen, Ido Kaminer, Hongsheng Chen, Baile Zhang, John D. Joannopoulos, and Marin SoljačićPNAS June 27, 2017 114 (26) 6717-6721; first published June 13, 2017. https://doi.org/10.1073/pnas.1701830114
Physics
- You have accessInterface-induced multiferroism by design in complex oxide superlatticesHangwen Guo, Zhen Wang, Shuai Dong, Saurabh Ghosh, Mohammad Saghayezhian, Lina Chen, Yakui Weng, Andreas Herklotz, Thomas Z. Ward, Rongying Jin, Sokrates T. Pantelides, Yimei Zhu, Jiandi Zhang, and E. W. PlummerPNAS June 27, 2017 114 (26) E5062-E5069; first published June 12, 2017. https://doi.org/10.1073/pnas.1706814114
Sustainability Science
- Open AccessEvaluation of a proposal for reliable low-cost grid power with 100% wind, water, and solarChristopher T. M. Clack, Staffan A. Qvist, Jay Apt, Morgan Bazilian, Adam R. Brandt, Ken Caldeira, Steven J. Davis, Victor Diakov, Mark A. Handschy, Paul D. H. Hines, Paulina Jaramillo, Daniel M. Kammen, Jane C. S. Long, M. Granger Morgan, Adam Reed, Varun Sivaram, James Sweeney, George R. Tynan, David G. Victor, John P. Weyant, and Jay F. WhitacrePNAS June 27, 2017 114 (26) 6722-6727; first published June 19, 2017. https://doi.org/10.1073/pnas.1610381114
Social Sciences
Environmental Sciences
- Open AccessEvaluation of a proposal for reliable low-cost grid power with 100% wind, water, and solarChristopher T. M. Clack, Staffan A. Qvist, Jay Apt, Morgan Bazilian, Adam R. Brandt, Ken Caldeira, Steven J. Davis, Victor Diakov, Mark A. Handschy, Paul D. H. Hines, Paulina Jaramillo, Daniel M. Kammen, Jane C. S. Long, M. Granger Morgan, Adam Reed, Varun Sivaram, James Sweeney, George R. Tynan, David G. Victor, John P. Weyant, and Jay F. WhitacrePNAS June 27, 2017 114 (26) 6722-6727; first published June 19, 2017. https://doi.org/10.1073/pnas.1610381114
Psychological and Cognitive Sciences
- You have accessSocioeconomic disadvantage, gestational immune activity, and neurodevelopment in early childhood
- From the Cover
Stephen E. Gilman, Mady Hornig, Akhgar Ghassabian, Jill Hahn, Sara Cherkerzian, Paul S. Albert, Stephen L. Buka, and Jill M. GoldsteinPNAS June 27, 2017 114 (26) 6728-6733; first published June 12, 2017. https://doi.org/10.1073/pnas.1617698114 - Open AccessWhen the appeal of a dominant leader is greater than a prestige leaderHemant Kakkar and Niro SivanathanPNAS June 27, 2017 114 (26) 6734-6739; first published June 12, 2017. https://doi.org/10.1073/pnas.1617711114
See companion article:
- Selective analysis is not credible evidence- Jan 23, 2018
Social Sciences
- You have accessNetwork dynamics of social influence in the wisdom of crowdsJoshua Becker, Devon Brackbill, and Damon CentolaPNAS June 27, 2017 114 (26) E5070-E5076; first published June 12, 2017. https://doi.org/10.1073/pnas.1615978114
See companion article:
- Learning is robust to noise- Oct 26, 2017
Biological Sciences
Agricultural Sciences
- You have accessBioengineered silkworms with butterfly cytotoxin-modified silk glands produce sericin cocoons with a utility for a new biomaterialRyosuke Otsuki, Masafumi Yamamoto, Erika Matsumoto, Shin-ichi Iwamoto, Hideki Sezutsu, Masumi Suzui, Keiko Takaki, Keiji Wakabayashi, Hajime Mori, and Eiji KotaniPNAS June 27, 2017 114 (26) 6740-6745; first published June 12, 2017. https://doi.org/10.1073/pnas.1703449114
- You have accessVector development and vitellogenin determine the transovarial transmission of begomovirusesJing Wei, Ya-Zhou He, Qi Guo, Tao Guo, Yin-Quan Liu, Xue-Ping Zhou, Shu-Sheng Liu, and Xiao-Wei WangPNAS June 27, 2017 114 (26) 6746-6751; first published June 12, 2017. https://doi.org/10.1073/pnas.1701720114
Applied Biological Sciences
- Open AccessImmunoengineering nerve repairNassir Mokarram, Kyle Dymanus, Akhil Srinivasan, Johnathan G. Lyon, John Tipton, Jason Chu, Arthur W. English, and Ravi V. BellamkondaPNAS June 27, 2017 114 (26) E5077-E5084; first published June 13, 2017. https://doi.org/10.1073/pnas.1705757114
- You have accessComputationally optimized deimmunization libraries yield highly mutated enzymes with low immunogenicity and enhanced activityRegina S. Salvat, Deeptak Verma, Andrew S. Parker, Jack R. Kirsch, Seth A. Brooks, Chris Bailey-Kellogg, and Karl E. GriswoldPNAS June 27, 2017 114 (26) E5085-E5093; first published June 12, 2017. https://doi.org/10.1073/pnas.1621233114
- You have accessMouse model of hematogenous implant-related Staphylococcus aureus biofilm infection reveals therapeutic targetsYu Wang, Lily I. Cheng, David R. Helfer, Alyssa G. Ashbaugh, Robert J. Miller, Alexander J. Tzomides, John M. Thompson, Roger V. Ortines, Andrew S. Tsai, Haiyun Liu, Carly A. Dillen, Nathan K. Archer, Taylor S. Cohen, Christine Tkaczyk, C. Kendall Stover, Bret R. Sellman, and Lloyd S. MillerPNAS June 27, 2017 114 (26) E5094-E5102; first published June 12, 2017. https://doi.org/10.1073/pnas.1703427114
Biochemistry
- You have accessTrigger loop of RNA polymerase is a positional, not acid–base, catalyst for both transcription and proofreadingTatiana V. Mishanina, Michael Z. Palo, Dhananjaya Nayak, Rachel A. Mooney, and Robert LandickPNAS June 27, 2017 114 (26) E5103-E5112; first published June 12, 2017. https://doi.org/10.1073/pnas.1702383114
- Open AccessCas1 and the Csy complex are opposing regulators of Cas2/3 nuclease activityMaryClare F. Rollins, Saikat Chowdhury, Joshua Carter, Sarah M. Golden, Royce A. Wilkinson, Joseph Bondy-Denomy, Gabriel C. Lander, and Blake WiedenheftPNAS June 27, 2017 114 (26) E5113-E5121; first published April 24, 2017. https://doi.org/10.1073/pnas.1616395114
See companion article:
- Type I-F Cas1–Cas2-3 CRISPR-Cas adaptation complex- Jun 13, 2017
- You have accessSpacer capture and integration by a type I-F Cas1–Cas2-3 CRISPR adaptation complexRobert D. Fagerlund, Max E. Wilkinson, Oleg Klykov, Arjan Barendregt, F. Grant Pearce, Sebastian N. Kieper, Howard W. R. Maxwell, Angela Capolupo, Albert J. R. Heck, Kurt L. Krause, Mihnea Bostina, Richard A. Scheltema, Raymond H. J. Staals, and Peter C. FineranPNAS June 27, 2017 114 (26) E5122-E5128; first published June 13, 2017. https://doi.org/10.1073/pnas.1618421114
See companion article:
- Structure and function of Cas1–2/3- Apr 24, 2017
- You have accessSelective oxidation of aliphatic C–H bonds in alkylphenols by a chemomimetic biocatalytic systemLei Du, Sheng Dong, Xingwang Zhang, Chengying Jiang, Jingfei Chen, Lishan Yao, Xiao Wang, Xiaobo Wan, Xi Liu, Xinquan Wang, Shaohua Huang, Qiu Cui, Yingang Feng, Shuang-Jiang Liu, and Shengying LiPNAS June 27, 2017 114 (26) E5129-E5137; first published June 12, 2017. https://doi.org/10.1073/pnas.1702317114
- You have accessEfficient, ultra-high-affinity chromatography in a one-step purification of complex proteinsMarina N. Vassylyeva, Sergiy Klyuyev, Alexey D. Vassylyev, Hunter Wesson, Zhuo Zhang, Matthew B. Renfrow, Hengbin Wang, N. Patrick Higgins, Louise T. Chow, and Dmitry G. VassylyevPNAS June 27, 2017 114 (26) E5138-E5147; first published June 12, 2017. https://doi.org/10.1073/pnas.1704872114
- Open AccessHuman genome-wide repair map of DNA damage caused by the cigarette smoke carcinogen benzo[a]pyreneWentao Li, Jinchuan Hu, Ogun Adebali, Sheera Adar, Yanyan Yang, Yi-Ying Chiou, and Aziz SancarPNAS June 27, 2017 114 (26) 6752-6757; first published June 12, 2017. https://doi.org/10.1073/pnas.1706021114
- Open AccessDynamic maps of UV damage formation and repair for the human genomeJinchuan Hu, Ogun Adebali, Sheera Adar, and Aziz SancarPNAS June 27, 2017 114 (26) 6758-6763; first published June 12, 2017. https://doi.org/10.1073/pnas.1706522114
- You have accessCrystal structures and atomic model of NADPH oxidaseFrancesca Magnani, Simone Nenci, Elisa Millana Fananas, Marta Ceccon, Elvira Romero, Marco W. Fraaije, and Andrea MatteviPNAS June 27, 2017 114 (26) 6764-6769; first published June 12, 2017. https://doi.org/10.1073/pnas.1702293114
Biophysics and Computational Biology
- Open AccessBroken flow symmetry explains the dynamics of small particles in deterministic lateral displacement arraysSung-Cheol Kim, Benjamin H. Wunsch, Huan Hu, Joshua T. Smith, Robert H. Austin, and Gustavo StolovitzkyPNAS June 27, 2017 114 (26) E5034-E5041; first published June 12, 2017. https://doi.org/10.1073/pnas.1706645114
- You have accessAdaptor protein mediates dynamic pump assembly for bacterial metal effluxAce George Santiago, Tai-Yen Chen, Lauren A. Genova, Won Jung, Alayna M. George Thompson, Megan M. McEvoy, and Peng ChenPNAS June 27, 2017 114 (26) 6694-6699; first published June 12, 2017. https://doi.org/10.1073/pnas.1704729114
- You have accessUbiquitin S65 phosphorylation engenders a pH-sensitive conformational switchXu Dong, Zhou Gong, Yun-Bi Lu, Kan Liu, Ling-Yun Qin, Meng-Lin Ran, Chang-Li Zhang, Zhu Liu, Wei-Ping Zhang, and Chun TangPNAS June 27, 2017 114 (26) 6770-6775; first published June 13, 2017. https://doi.org/10.1073/pnas.1705718114
- You have accessWeak protein–protein interactions in live cells are quantified by cell-volume modulationShahar Sukenik, Pin Ren, and Martin GruebelePNAS June 27, 2017 114 (26) 6776-6781; first published June 12, 2017. https://doi.org/10.1073/pnas.1700818114
- You have accessCa2+-induced movement of tropomyosin on native cardiac thin filaments revealed by cryoelectron microscopyCristina Risi, Jamie Eisner, Betty Belknap, David H. Heeley, Howard D. White, Gunnar F. Schröder, and Vitold E. GalkinPNAS June 27, 2017 114 (26) 6782-6787; first published June 12, 2017. https://doi.org/10.1073/pnas.1700868114
Cell Biology
- You have accessRetroviral host range extension is coupled with Env-activating mutations resulting in receptor-independent entryAnna Lounková, Jan Kosla, David Přikryl, Kryštof Štafl, Dana Kučerová, and Jan SvobodaPNAS June 27, 2017 114 (26) E5148-E5157; first published June 12, 2017. https://doi.org/10.1073/pnas.1704750114
- You have accessDeubiquitinating enzyme VCIP135 dictates the duration of botulinum neurotoxin type A intoxicationYien Che Tsai, Archana Kotiya, Erkan Kiris, Mei Yang, Sina Bavari, Lino Tessarollo, George A. Oyler, and Allan M. WeissmanPNAS June 27, 2017 114 (26) E5158-E5166; first published June 5, 2017. https://doi.org/10.1073/pnas.1621076114
- Open AccessOptogenetic control of mitochondrial metabolism and Ca2+ signaling by mitochondria-targeted opsinsTatiana Tkatch, Elisa Greotti, Gytis Baranauskas, Diana Pendin, Soumitra Roy, Luliaoana I. Nita, Jennifer Wettmarshausen, Matthias Prigge, Ofer Yizhar, Orian S. Shirihai, Daniel Fishman, Michal Hershfinkel, Ilya A. Fleidervish, Fabiana Perocchi, Tullio Pozzan, and Israel SeklerPNAS June 27, 2017 114 (26) E5167-E5176; first published June 13, 2017. https://doi.org/10.1073/pnas.1703623114
- Open AccessProstaglandin E2 is essential for efficacious skeletal muscle stem-cell function, augmenting regeneration and strength
- Inaugural Article
Andrew T. V. Ho, Adelaida R. Palla, Matthew R. Blake, Nora D. Yucel, Yu Xin Wang, Klas E. G. Magnusson, Colin A. Holbrook, Peggy E. Kraft, Scott L. Delp, and Helen M. BlauPNAS June 27, 2017 114 (26) 6675-6684; first published June 12, 2017. https://doi.org/10.1073/pnas.1705420114See companion article:
- Profile of Helen M. Blau- Oct 16, 2017
Developmental Biology
- You have accessBiomechanical coupling facilitates spinal neural tube closure in mouse embryosGabriel L. Galea, Young-June Cho, Gauden Galea, Matteo A. Molè, Ana Rolo, Dawn Savery, Dale Moulding, Lucy H. Culshaw, Evanthia Nikolopoulou, Nicholas D. E. Greene, and Andrew J. CoppPNAS June 27, 2017 114 (26) E5177-E5186; first published June 12, 2017. https://doi.org/10.1073/pnas.1700934114
Ecology
- Open AccessHow temporal patterns in rainfall determine the geomorphology and carbon fluxes of tropical peatlandsAlexander R. Cobb, Alison M. Hoyt, Laure Gandois, Jangarun Eri, René Dommain, Kamariah Abu Salim, Fuu Ming Kai, Nur Salihah Haji Su’ut, and Charles F. HarveyPNAS June 27, 2017 114 (26) E5187-E5196; first published June 12, 2017. https://doi.org/10.1073/pnas.1701090114
- You have accessSynchrony affects Taylor’s law in theory and data
- From the Cover
Daniel C. Reuman, Lei Zhao, Lawrence W. Sheppard, Philip C. Reid, and Joel E. CohenPNAS June 27, 2017 114 (26) 6788-6793; first published May 30, 2017. https://doi.org/10.1073/pnas.1703593114See companion article:
- Unfinished synchrony- Jun 12, 2017
- You have accessFamily-transmitted stress in a wild birdJosé C. Noguera, Sin-Yeon Kim, and Alberto VelandoPNAS June 27, 2017 114 (26) 6794-6799; first published June 12, 2017. https://doi.org/10.1073/pnas.1706164114
Evolution
- You have accessFemales manipulate behavior of caring males via prenatal maternal effects
- From the Cover
Matthieu Paquet and Per T. SmisethPNAS June 27, 2017 114 (26) 6800-6805; first published June 12, 2017. https://doi.org/10.1073/pnas.1619759114
Genetics
- You have accessSkin-specific regulation of SREBP processing and lipid biosynthesis by glycerol kinase 5Duanwu Zhang, Wataru Tomisato, Lijing Su, Lei Sun, Jin Huk Choi, Zhao Zhang, Kuan-wen Wang, Xiaoming Zhan, Mihwa Choi, Xiaohong Li, Miao Tang, Jose M. Castro-Perez, Sara Hildebrand, Anne R. Murray, Eva Marie Y. Moresco, and Bruce BeutlerPNAS June 27, 2017 114 (26) E5197-E5206; first published June 12, 2017. https://doi.org/10.1073/pnas.1705312114
- You have accessGenome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicingTeng Fei, Yiwen Chen, Tengfei Xiao, Wei Li, Laura Cato, Peng Zhang, Maura B. Cotter, Michaela Bowden, Rosina T. Lis, Shuang G. Zhao, Qiu Wu, Felix Y. Feng, Massimo Loda, Housheng Hansen He, X. Shirley Liu, and Myles BrownPNAS June 27, 2017 114 (26) E5207-E5215; first published June 13, 2017. https://doi.org/10.1073/pnas.1617467114
Immunology and Inflammation
- You have accessSystems-guided forward genetic screen reveals a critical role of the replication stress response protein ETAA1 in T cell clonal expansionLisa A. Miosge, Yovina Sontani, Aaron Chuah, Keisuke Horikawa, Tiffany A. Russell, Yan Mei, Mayura V. Wagle, Debbie R. Howard, Anselm Enders, David C. Tscharke, Christopher C. Goodnow, and Ian A. ParishPNAS June 27, 2017 114 (26) E5216-E5225; first published June 12, 2017. https://doi.org/10.1073/pnas.1705795114
- You have accessSocioeconomic disadvantage, gestational immune activity, and neurodevelopment in early childhood
- From the Cover
Stephen E. Gilman, Mady Hornig, Akhgar Ghassabian, Jill Hahn, Sara Cherkerzian, Paul S. Albert, Stephen L. Buka, and Jill M. GoldsteinPNAS June 27, 2017 114 (26) 6728-6733; first published June 12, 2017. https://doi.org/10.1073/pnas.1617698114 - You have accessStructural studies of viperin, an antiviral radical SAM enzymeMichael K. Fenwick, Yue Li, Peter Cresswell, Yorgo Modis, and Steven E. EalickPNAS June 27, 2017 114 (26) 6806-6811; first published June 12, 2017. https://doi.org/10.1073/pnas.1705402114
Medical Sciences
- You have accessMaintenance of antiangiogenic and antitumor effects by orally active low-dose capecitabine for long-term cancer therapyYin Zhang, Meili Sun, Guichun Huang, Linlin Yin, Qinghua Lai, Yunlong Yang, Xiaoming Xing, Guohua Yu, Yuping Sun, Xinsheng Wang, Guohui Nie, Yizhi Liu, and Yihai CaoPNAS June 27, 2017 114 (26) E5226-E5235; first published June 12, 2017. https://doi.org/10.1073/pnas.1705066114
- You have accessIntraoperative assessment of tumor margins during glioma resection by desorption electrospray ionization-mass spectrometryValentina Pirro, Clint M. Alfaro, Alan K. Jarmusch, Eyas M. Hattab, Aaron A. Cohen-Gadol, and R. Graham CooksPNAS June 27, 2017 114 (26) 6700-6705; first published June 12, 2017. https://doi.org/10.1073/pnas.1706459114
- You have accessSelective replication of oncolytic virus M1 results in a bystander killing effect that is potentiated by Smac mimeticsJing Cai, Yuan Lin, Haipeng Zhang, Jiankai Liang, Yaqian Tan, Webster K. Cavenee, and Guangmei YanPNAS June 27, 2017 114 (26) 6812-6817; first published June 12, 2017. https://doi.org/10.1073/pnas.1701002114
Microbiology
- You have accessElectron-shuttling antibiotics structure bacterial communities by modulating cellular levels of c-di-GMPChinweike Okegbe, Blanche L. Fields, Stephanie J. Cole, Christopher Beierschmitt, Chase J. Morgan, Alexa Price-Whelan, Richard C. Stewart, Vincent T. Lee, and Lars E. P. DietrichPNAS June 27, 2017 114 (26) E5236-E5245; first published June 12, 2017. https://doi.org/10.1073/pnas.1700264114
- You have accessInterplay between tolerance mechanisms to copper and acid stress in Escherichia coliKarrera Y. Djoko, Minh-Duy Phan, Kate M. Peters, Mark J. Walker, Mark A. Schembri, and Alastair G. McEwanPNAS June 27, 2017 114 (26) 6818-6823; first published June 13, 2017. https://doi.org/10.1073/pnas.1620232114
- Open AccessRNA target profiles direct the discovery of virulence functions for the cold-shock proteins CspC and CspECharlotte Michaux, Erik Holmqvist, Erin Vasicek, Malvika Sharan, Lars Barquist, Alexander J. Westermann, John S. Gunn, and Jörg VogelPNAS June 27, 2017 114 (26) 6824-6829; first published June 13, 2017. https://doi.org/10.1073/pnas.1620772114
Neuroscience
- Open AccessNumbers of presynaptic Ca2+ channel clusters match those of functionally defined vesicular docking sites in single central synapsesTakafumi Miki, Walter A. Kaufmann, Gerardo Malagon, Laura Gomez, Katsuhiko Tabuchi, Masahiko Watanabe, Ryuichi Shigemoto, and Alain MartyPNAS June 27, 2017 114 (26) E5246-E5255; first published June 12, 2017. https://doi.org/10.1073/pnas.1704470114
- You have accessRegulation of spinogenesis in mature Purkinje cells via mGluR/PKC-mediated phosphorylation of CaMKIIβTakeyuki Sugawara, Chihiro Hisatsune, Hiroyuki Miyamoto, Naoko Ogawa, and Katsuhiko MikoshibaPNAS June 27, 2017 114 (26) E5256-E5265; first published June 12, 2017. https://doi.org/10.1073/pnas.1617270114
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Physiology
- You have accessSpecific targeting of TGF-β family ligands demonstrates distinct roles in the regulation of muscle mass in health and diseaseJustin L. Chen, Kelly L. Walton, Adam Hagg, Timothy D. Colgan, Katharine Johnson, Hongwei Qian, Paul Gregorevic, and Craig A. HarrisonPNAS June 27, 2017 114 (26) E5266-E5275; first published June 12, 2017. https://doi.org/10.1073/pnas.1620013114
- You have accessPharmacology of the Nav1.1 domain IV voltage sensor reveals coupling between inactivation gating processesJeremiah D. Osteen, Kevin Sampson, Vivek Iyer, David Julius, and Frank BosmansPNAS June 27, 2017 114 (26) 6836-6841; first published June 12, 2017. https://doi.org/10.1073/pnas.1621263114
- Open AccessGel-forming mucins form distinct morphologic structures in airwaysLynda S. Ostedgaard, Thomas O. Moninger, James D. McMenimen, Nicholas M. Sawin, Connor P. Parker, Ian M. Thornell, Linda S. Powers, Nicholas D. Gansemer, Drake C. Bouzek, Daniel P. Cook, David K. Meyerholz, Mahmoud H. Abou Alaiwa, David A. Stoltz, and Michael J. WelshPNAS June 27, 2017 114 (26) 6842-6847; first published June 12, 2017. https://doi.org/10.1073/pnas.1703228114
Plant Biology
- You have accessMicrosymbiont discrimination mediated by a host-secreted peptide in Medicago truncatulaShengming Yang, Qi Wang, Elena Fedorova, Jinge Liu, Qiulin Qin, Qiaolin Zheng, Paul A. Price, Huairong Pan, Dong Wang, Joel S. Griffitts, Ton Bisseling, and Hongyan ZhuPNAS June 27, 2017 114 (26) 6848-6853; first published June 12, 2017. https://doi.org/10.1073/pnas.1700460114
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- NCRs regulate specificity in rhizobial symbiosis- Jun 12, 2017
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- Negative regulation of symbiosis by NCR peptides- Jun 12, 2017
- Open AccessCarbohydrate microarrays and their use for the identification of molecular markers for plant cell wall compositionIan P. Wood, Bruce M. Pearson, Enriqueta Garcia-Gutierrez, Lenka Havlickova, Zhesi He, Andrea L. Harper, Ian Bancroft, and Keith W. WaldronPNAS June 27, 2017 114 (26) 6860-6865; first published June 12, 2017. https://doi.org/10.1073/pnas.1619033114
- You have accessA recruiting protein of geranylgeranyl diphosphate synthase controls metabolic flux toward chlorophyll biosynthesis in riceFei Zhou, Cheng-Yuan Wang, Michael Gutensohn, Ling Jiang, Peng Zhang, Dabing Zhang, Natalia Dudareva, and Shan LuPNAS June 27, 2017 114 (26) 6866-6871; first published June 12, 2017. https://doi.org/10.1073/pnas.1705689114
Corrections (Online Only)
- You have accessCorrection for Brumberg et al., Single-crystal Ih ice surfaces unveil connection between macroscopic and molecular structurePNAS June 27, 2017 114 (26) E5276; first published June 19, 2017. https://doi.org/10.1073/pnas.1708643114
- You have accessCorrection for Khan et al., Sympathetic innervation controls homeostasis of neuromuscular junctions in health and diseasePNAS June 27, 2017 114 (26) E5277; first published June 19, 2017. https://doi.org/10.1073/pnas.1708559114
SI Correction (Online Only)
- You have accessCorrection to Supporting Information for Suzuki et al., Behavioral contagion during learning about another agent’s risk-preferences acts on the neural representation of decision-riskPNAS June 27, 2017 114 (26) E5278; first published June 19, 2017. https://doi.org/10.1073/pnas.1708546114
Retraction (Online Only)
- You have accessRetraction for Zimmerman et al., Signaling through hepatocellular A2B adenosine receptors dampens ischemia and reperfusion injury of the liverPNAS June 27, 2017 114 (26) E5279; first published June 19, 2017. https://doi.org/10.1073/pnas.1708494114
Commentaries
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