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Research Article

Predicting gene regulatory networks by combining spatial and temporal gene expression data in Arabidopsis root stem cells

Maria Angels de Luis Balaguer, Adam P. Fisher, Natalie M. Clark, Maria Guadalupe Fernandez-Espinosa, Barbara K. Möller, Dolf Weijers, View ORCID ProfileJan U. Lohmann, Cranos Williams, Oscar Lorenzo, and Rosangela Sozzani
  1. aPlant and Microbial Biology Department, North Carolina State University, Raleigh, NC 27695;
  2. bBiomathematics Program, North Carolina State University, Raleigh, NC 27695;
  3. cDepartamento de Botánica y Fisiología Vegetal, Instituto Hispano-Luso de Investigaciones Agrarias, Facultad de Biología, Universidad de Salamanca, 37185 Salamanca, Spain;
  4. dLaboratory of Biochemistry, Wageningen University, 6703HA, Wageningen, The Netherlands;
  5. eDepartment of Stem Cell Biology, University of Heidelberg, Heidelberg D-69120, Germany;
  6. fElectrical and Computer Engineering Department, North Carolina State University, Raleigh, NC 27695

See allHide authors and affiliations

PNAS September 5, 2017 114 (36) E7632-E7640; first published August 21, 2017; https://doi.org/10.1073/pnas.1707566114
Maria Angels de Luis Balaguer
aPlant and Microbial Biology Department, North Carolina State University, Raleigh, NC 27695;
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Adam P. Fisher
aPlant and Microbial Biology Department, North Carolina State University, Raleigh, NC 27695;
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Natalie M. Clark
aPlant and Microbial Biology Department, North Carolina State University, Raleigh, NC 27695;
bBiomathematics Program, North Carolina State University, Raleigh, NC 27695;
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Maria Guadalupe Fernandez-Espinosa
cDepartamento de Botánica y Fisiología Vegetal, Instituto Hispano-Luso de Investigaciones Agrarias, Facultad de Biología, Universidad de Salamanca, 37185 Salamanca, Spain;
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Barbara K. Möller
dLaboratory of Biochemistry, Wageningen University, 6703HA, Wageningen, The Netherlands;
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Dolf Weijers
dLaboratory of Biochemistry, Wageningen University, 6703HA, Wageningen, The Netherlands;
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Jan U. Lohmann
eDepartment of Stem Cell Biology, University of Heidelberg, Heidelberg D-69120, Germany;
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  • ORCID record for Jan U. Lohmann
Cranos Williams
fElectrical and Computer Engineering Department, North Carolina State University, Raleigh, NC 27695
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Oscar Lorenzo
cDepartamento de Botánica y Fisiología Vegetal, Instituto Hispano-Luso de Investigaciones Agrarias, Facultad de Biología, Universidad de Salamanca, 37185 Salamanca, Spain;
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Rosangela Sozzani
aPlant and Microbial Biology Department, North Carolina State University, Raleigh, NC 27695;
bBiomathematics Program, North Carolina State University, Raleigh, NC 27695;
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  • For correspondence: ross_sozzani@ncsu.edu
  1. Edited by Julia Bailey-Serres, University of California, Riverside, CA, and approved July 31, 2017 (received for review May 7, 2017)

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Article Information

vol. 114 no. 36 E7632-E7640
DOI: 
https://doi.org/10.1073/pnas.1707566114
PubMed: 
28827319

Published By: 
National Academy of Sciences
Print ISSN: 
0027-8424
Online ISSN: 
1091-6490
History: 
  • Published in issue September 5, 2017.
  • Published first August 21, 2017.

Copyright & Usage: 

Author Information

  1. Maria Angels de Luis Balaguera,
  2. Adam P. Fishera,
  3. Natalie M. Clarka,b,
  4. Maria Guadalupe Fernandez-Espinosac,
  5. Barbara K. Möllerd,1,
  6. Dolf Weijersd,
  7. Jan U. Lohmanne,
  8. Cranos Williamsf,
  9. Oscar Lorenzoc, and
  10. Rosangela Sozzania,b,2
  1. aPlant and Microbial Biology Department, North Carolina State University, Raleigh, NC 27695;
  2. bBiomathematics Program, North Carolina State University, Raleigh, NC 27695;
  3. cDepartamento de Botánica y Fisiología Vegetal, Instituto Hispano-Luso de Investigaciones Agrarias, Facultad de Biología, Universidad de Salamanca, 37185 Salamanca, Spain;
  4. dLaboratory of Biochemistry, Wageningen University, 6703HA, Wageningen, The Netherlands;
  5. eDepartment of Stem Cell Biology, University of Heidelberg, Heidelberg D-69120, Germany;
  6. fElectrical and Computer Engineering Department, North Carolina State University, Raleigh, NC 27695
  1. Edited by Julia Bailey-Serres, University of California, Riverside, CA, and approved July 31, 2017 (received for review May 7, 2017)

Footnotes

  • ↵1Present addresses: Department of Plant Systems Biology, Flanders Institute for Biotechnology (VIB), B-9052 Ghent, Belgium; and Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium.

  • ↵2To whom correspondence should be addressed. Email: ross_sozzani{at}ncsu.edu.
  • Author contributions: M.A.d.L.B. and R.S. designed research; M.A.d.L.B., A.P.F., N.M.C., M.G.F.-E., B.K.M., D.W., O.L., and R.S. performed research; J.U.L. and C.W. contributed new reagents/analytic tools; M.A.d.L.B., A.P.F., and N.M.C. analyzed data; and M.A.d.L.B. and R.S. wrote the paper.

  • The authors declare no conflict of interest.

  • This article is a PNAS Direct Submission.

  • Data deposition: The data reported in this paper have been deposited in the Gene Expression Omnibus (GEO) database, https://www.ncbi.nlm.nih.gov/geo (accession nos. GSE76710, GSE97792, and GSE97857).

  • This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1707566114/-/DCSupplemental.

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Article usage

Article usage: August 2017 to April 2021

AbstractFullPdf
Aug 20172327156294
Sep 20174942173344
Oct 20171172110124
Nov 201725441632120
Dec 20176079486744
Total 2017170646938926
Jan 20185039423852
Feb 20182186465933
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May 201819817546
Jun 201821518458
Jul 201815912731
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Total 2018880810692612
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Apr 20192524573
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Jun 20192611738
Jul 2019811444
Aug 2019109941
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Dec 20191712345
Total 20192361744570
Jan 20201512317
Feb 2020911331
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Apr 20201812759
May 20205312562
Jun 20203313853
Jul 20202813849
Aug 20202810338
Sep 20203211136
Oct 20201815946
Nov 20205713635
Dec 2020377934
Total 20203531482502
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Feb 20211710447
Mar 20214112065
Apr 2021187633
Total 202199403188
Total26560212592798
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Predicting GRNs in Arabidopsis root stem cells
Maria Angels de Luis Balaguer, Adam P. Fisher, Natalie M. Clark, Maria Guadalupe Fernandez-Espinosa, Barbara K. Möller, Dolf Weijers, Jan U. Lohmann, Cranos Williams, Oscar Lorenzo, Rosangela Sozzani
Proceedings of the National Academy of Sciences Sep 2017, 114 (36) E7632-E7640; DOI: 10.1073/pnas.1707566114

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Predicting GRNs in Arabidopsis root stem cells
Maria Angels de Luis Balaguer, Adam P. Fisher, Natalie M. Clark, Maria Guadalupe Fernandez-Espinosa, Barbara K. Möller, Dolf Weijers, Jan U. Lohmann, Cranos Williams, Oscar Lorenzo, Rosangela Sozzani
Proceedings of the National Academy of Sciences Sep 2017, 114 (36) E7632-E7640; DOI: 10.1073/pnas.1707566114
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