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Research Article

Site-directed RNA repair of endogenous Mecp2 RNA in neurons

John R. Sinnamon, Susan Y. Kim, Glen M. Corson, Zhen Song, Hiroyuki Nakai, John P. Adelman, and Gail Mandel
PNAS October 31, 2017 114 (44) E9395-E9402; first published October 16, 2017; https://doi.org/10.1073/pnas.1715320114
John R. Sinnamon
aVollum Institute, Oregon Health and Science University, Portland, OR 97239;
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Susan Y. Kim
aVollum Institute, Oregon Health and Science University, Portland, OR 97239;
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Glen M. Corson
aVollum Institute, Oregon Health and Science University, Portland, OR 97239;
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Zhen Song
bDepartment of Molecular and Medical Genetics, Oregon Health and Science University, Portland, OR 97239
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Hiroyuki Nakai
bDepartment of Molecular and Medical Genetics, Oregon Health and Science University, Portland, OR 97239
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John P. Adelman
aVollum Institute, Oregon Health and Science University, Portland, OR 97239;
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Gail Mandel
aVollum Institute, Oregon Health and Science University, Portland, OR 97239;
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  • For correspondence: mandelg@ohsu.edu
  1. Contributed by Gail Mandel, September 22, 2017 (sent for review August 30, 2017; reviewed by Gordon G. Carmichael and Stuart Cobb)

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Article Information

vol. 114 no. 44 E9395-E9402
DOI: 
https://doi.org/10.1073/pnas.1715320114
PubMed: 
29078406

Published By: 
National Academy of Sciences
Print ISSN: 
0027-8424
Online ISSN: 
1091-6490
History: 
  • Published in issue October 31, 2017.
  • Published first October 16, 2017.

Article Versions

  • Previous version (October 16, 2017 - 12:05).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
© 2017 Published under the PNAS license.

Author Information

  1. John R. Sinnamona,1,
  2. Susan Y. Kima,1,
  3. Glen M. Corsona,
  4. Zhen Songb,
  5. Hiroyuki Nakaib,
  6. John P. Adelmana, and
  7. Gail Mandela,2
  1. aVollum Institute, Oregon Health and Science University, Portland, OR 97239;
  2. bDepartment of Molecular and Medical Genetics, Oregon Health and Science University, Portland, OR 97239
  1. Contributed by Gail Mandel, September 22, 2017 (sent for review August 30, 2017; reviewed by Gordon G. Carmichael and Stuart Cobb)

Footnotes

  • ↵1J.R.S. and S.Y.K. contributed equally to this work.

  • ↵2To whom correspondence should be addressed. Email: mandelg{at}ohsu.edu.
  • Author contributions: J.R.S., S.Y.K., G.M.C., H.N., J.P.A., and G.M. designed research; J.R.S., S.Y.K., G.M.C., and Z.S. performed research; H.N. contributed new reagents/analytic tools; J.R.S., S.Y.K., G.M.C., J.P.A., and G.M. analyzed data; and J.R.S., J.P.A., and G.M. wrote the paper.

  • Reviewers: G.G.C., University of Connecticut Health Center; and S.C., University of Glasgow.

  • The authors declare no conflict of interest.

  • This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1715320114/-/DCSupplemental.

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Article usage

Article usage: October 2017 to February 2021

AbstractFullPdf
Oct 20172360106168
Nov 20173047122174
Dec 20178943522
Total 20176301263364
Jan 20188235138
Feb 20184653320
Mar 20181875229
Apr 20181976728
May 2018759036
Jun 2018739038
Jul 2018768032
Aug 2018859028
Sep 2018737320
Oct 2018129628
Nov 2018118422
Dec 201859828
Total 20182082904347
Jan 201967133
Feb 2019186227
Mar 2019245740
Apr 2019126145
May 2019105930
Jun 2019105836
Jul 2019196937
Aug 201985824
Sep 2019105629
Oct 2019125931
Nov 201995325
Dec 201923924
Total 2019140702381
Jan 2020125731
Feb 2020109143
Mar 2020155728
Apr 2020107429
May 2020144330
Jun 2020136426
Jul 2020226136
Aug 2020115231
Sep 202036829
Oct 2020116839
Nov 2020186637
Dec 2020217931
Total 2020160780390
Jan 2021185440
Feb 2021117939
Total 20212913379
Total871227821561
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Site-directed RNA repair of endogenous Mecp2 RNA
John R. Sinnamon, Susan Y. Kim, Glen M. Corson, Zhen Song, Hiroyuki Nakai, John P. Adelman, Gail Mandel
Proceedings of the National Academy of Sciences Oct 2017, 114 (44) E9395-E9402; DOI: 10.1073/pnas.1715320114

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Site-directed RNA repair of endogenous Mecp2 RNA
John R. Sinnamon, Susan Y. Kim, Glen M. Corson, Zhen Song, Hiroyuki Nakai, John P. Adelman, Gail Mandel
Proceedings of the National Academy of Sciences Oct 2017, 114 (44) E9395-E9402; DOI: 10.1073/pnas.1715320114
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