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Table of Contents
December 26, 2017; vol. 114 no. 52
This Week in PNAS
Reviewer Acknowledgment (Online Only)
Letter (Online Only)
- You have accessIntercellular competition and levels of development: The plasticity of inevitabilityRobert B. Eckhardt, Alex S. Weller, and Maciej HennebergPNAS December 26, 2017 114 (52) E11061-E11062; published ahead of print December 12, 2017. https://doi.org/10.1073/pnas.1719479115
Opinion
Leading scientists discuss current issues.
- You have accessOpinion: Why we need a National Living Soil Repository
- Front Matter
Daniel K. Manter, Jorge A. Delgado, Harvey D. Blackburn, Daren Harmel, Adalberto A. Pérez de León, and C. Wayne Honeycutt
PNAS Plus Significance Statements
Brief statements written by the authors about the significance of their papers.
Physical Sciences
Applied Physical Sciences
- Open AccessMaking two-photon processes dominate one-photon processes using mid-IR phonon polaritonsNicholas Rivera, Gilles Rosolen, John D. Joannopoulos, Ido Kaminer, and Marin SoljačićPNAS December 26, 2017 114 (52) 13607-13612; published ahead of print December 12, 2017. https://doi.org/10.1073/pnas.1713538114
Biophysics and Computational Biology
- You have accessHow reduced excitonic coupling enhances light harvesting in the main photosynthetic antennae of diatomsTjaart P. J. Krüger, Pavel Malý, Maxime T. A. Alexandre, Tomáš Mančal, Claudia Büchel, and Rienk van GrondellePNAS December 26, 2017 114 (52) E11063-E11071; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1714656115
Chemistry
- You have accessUltrafast 25-fs relaxation in highly excited states of methyl azide mediated by strong nonadiabatic coupling
- From the Cover
William K. Peters, David E. Couch, Benoit Mignolet, Xuetao Shi, Quynh L. Nguyen, Ryan C. Fortenberry, H. Bernhard Schlegel, Françoise Remacle, Henry C. Kapteyn, Margaret M. Murnane, and Wen LiPNAS December 26, 2017 114 (52) E11072-E11081; published ahead of print November 6, 2017. https://doi.org/10.1073/pnas.1712566114 - You have accessDesigning flexible 2D transition metal carbides with strain-controllable lithium storageHang Zhang, Zhongheng Fu, Ruifeng Zhang, Qianfan Zhang, Hongzhen Tian, Dominik Legut, Timothy C. Germann, Yuanqi Guo, Shiyu Du, and Joseph S. FranciscoPNAS December 26, 2017 114 (52) E11082-E11091; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1717219115
- You have accessUltrafast rotation in an amphidynamic crystalline metal organic frameworkCortnie S. Vogelsberg, Fernando J. Uribe-Romo, Andrew S. Lipton, Song Yang, K. N. Houk, Stuart Brown, and Miguel A. Garcia-GaribayPNAS December 26, 2017 114 (52) 13613-13618; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1708817115
- You have accessAutocatalytic surface reduction and its role in controlling seed-mediated growth of colloidal metal nanocrystalsTung-Han Yang, Shan Zhou, Kyle D. Gilroy, Legna Figueroa-Cosme, Yi-Hsien Lee, Jenn-Ming Wu, and Younan XiaPNAS December 26, 2017 114 (52) 13619-13624; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1713907114
- Open AccessSE2 reaction in noncarbon system: Metal-halide catalysis for dehydrogenation of ammonia boraneSung Jin Pai and Sang Soo HanPNAS December 26, 2017 114 (52) 13625-13630; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1712137115
- You have accessAllosteric histidine switch for regulation of intracellular zinc(II) fluctuationRongfeng Zhu, Yanqun Song, Haiping Liu, Yufei Yang, Shenlin Wang, Chengqi Yi, and Peng R. ChenPNAS December 26, 2017 114 (52) 13661-13666; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1708563115
Earth, Atmospheric, and Planetary Sciences
- You have accessGlobal biogeochemical cycle of vanadiumWilliam H. Schlesinger, Emily M. Klein, and Avner VengoshPNAS December 26, 2017 114 (52) E11092-E11100; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1715500114
Engineering
- You have accessUnderstanding the mechanisms of amorphous creep through molecular simulationPenghui Cao, Michael P. Short, and Sidney YipPNAS December 26, 2017 114 (52) 13631-13636; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1708618114
- You have accessSingle-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistanceYapeng Su, Wei Wei, Lidia Robert, Min Xue, Jennifer Tsoi, Angel Garcia-Diaz, Blanca Homet Moreno, Jungwoo Kim, Rachel H. Ng, Jihoon W. Lee, Richard C. Koya, Begonya Comin-Anduix, Thomas G. Graeber, Antoni Ribas, and James R. HeathPNAS December 26, 2017 114 (52) 13679-13684; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1712064115
Environmental Sciences
- You have accessEarliest hydraulic enterprise in China, 5,100 years ago
- From the Cover
Bin Liu, Ningyuan Wang, Minghui Chen, Xiaohong Wu, Duowen Mo, Jianguo Liu, Shijin Xu, and Yijie ZhuangPNAS December 26, 2017 114 (52) 13637-13642; published ahead of print December 4, 2017. https://doi.org/10.1073/pnas.1710516114
Social Sciences
Anthropology
- Open AccessPopulation is the main driver of war group size and conflict casualtiesRahul C. Oka, Marc Kissel, Mark Golitko, Susan Guise Sheridan, Nam C. Kim, and Agustín FuentesPNAS December 26, 2017 114 (52) E11101-E11110; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1713972114
- You have accessEarliest hydraulic enterprise in China, 5,100 years ago
- From the Cover
Bin Liu, Ningyuan Wang, Minghui Chen, Xiaohong Wu, Duowen Mo, Jianguo Liu, Shijin Xu, and Yijie ZhuangPNAS December 26, 2017 114 (52) 13637-13642; published ahead of print December 4, 2017. https://doi.org/10.1073/pnas.1710516114
Psychological and Cognitive Sciences
- You have accessDefault neglect in attempts at social influenceJulian J. Zlatev, David P. Daniels, Hajin Kim, and Margaret A. NealePNAS December 26, 2017 114 (52) 13643-13648; published ahead of print December 8, 2017. https://doi.org/10.1073/pnas.1712757114
Biological Sciences
Anthropology
- Open AccessPopulation is the main driver of war group size and conflict casualtiesRahul C. Oka, Marc Kissel, Mark Golitko, Susan Guise Sheridan, Nam C. Kim, and Agustín FuentesPNAS December 26, 2017 114 (52) E11101-E11110; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1713972114
- Open AccessSex determination of human remains from peptides in tooth enamelNicolas Andre Stewart, Raquel Fernanda Gerlach, Rebecca L. Gowland, Kurt J. Gron, and Janet MontgomeryPNAS December 26, 2017 114 (52) 13649-13654; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1714926115
Applied Biological Sciences
- You have accessMolecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCsMing-Tao Zhao, Haodong Chen, Qing Liu, Ning-Yi Shao, Nazish Sayed, Hung-Ta Wo, Joe Z. Zhang, Sang-Ging Ong, Chun Liu, Youngkyun Kim, Huaxiao Yang, Tony Chour, Hong Ma, Nuria Marti Gutierrez, Ioannis Karakikes, Shoukhrat Mitalipov, Michael P. Snyder, and Joseph C. WuPNAS December 26, 2017 114 (52) E11111-E11120; published ahead of print December 4, 2017. https://doi.org/10.1073/pnas.1708991114
- You have accessPSMA-targeted polyinosine/polycytosine vector induces prostate tumor regression and invokes an antitumor immune response in miceYael Langut, Alaa Talhami, Samarasimhareddy Mamidi, Alexei Shir, Maya Zigler, Salim Joubran, Anna Sagalov, Efrat Flashner-Abramson, Nufar Edinger, Shoshana Klein, and Alexander LevitzkiPNAS December 26, 2017 114 (52) 13655-13660; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1714587115
Biochemistry
- You have accessComparative transcriptomics as a guide to natural product discovery and biosynthetic gene cluster functionalityGregory C. A. Amos, Takayoshi Awakawa, Robert N. Tuttle, Anne-Catrin Letzel, Min Cheol Kim, Yuta Kudo, William Fenical, Bradley S. Moore, and Paul R. JensenPNAS December 26, 2017 114 (52) E11121-E11130; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1714381115
- You have accessDiscovery of the leinamycin family of natural products by mining actinobacterial genomesGuohui Pan, Zhengren Xu, Zhikai Guo, Hindra, Ming Ma, Dong Yang, Hao Zhou, Yannick Gansemans, Xiangcheng Zhu, Yong Huang, Li-Xing Zhao, Yi Jiang, Jinhua Cheng, Filip Van Nieuwerburgh, Joo-Won Suh, Yanwen Duan, and Ben ShenPNAS December 26, 2017 114 (52) E11131-E11140; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1716245115
- You have accessRapid, direct activity assays for Smoothened reveal Hedgehog pathway regulation by membrane cholesterol and extracellular sodiumBenjamin R. Myers, Lila Neahring, Yunxiao Zhang, Kelsey J. Roberts, and Philip A. BeachyPNAS December 26, 2017 114 (52) E11141-E11150; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1717891115
- You have accessAllosteric histidine switch for regulation of intracellular zinc(II) fluctuationRongfeng Zhu, Yanqun Song, Haiping Liu, Yufei Yang, Shenlin Wang, Chengqi Yi, and Peng R. ChenPNAS December 26, 2017 114 (52) 13661-13666; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1708563115
- You have accessDistinct roles of N- and O-glycans in cellulase activity and stabilityAntonella Amore, Brandon C. Knott, Nitin T. Supekar, Asif Shajahan, Parastoo Azadi, Peng Zhao, Lance Wells, Jeffrey G. Linger, Sarah E. Hobdey, Todd A. Vander Wall, Todd Shollenberger, John M. Yarbrough, Zhongping Tan, Michael F. Crowley, Michael E. Himmel, Stephen R. Decker, Gregg T. Beckham, and Larry E. Taylor IIPNAS December 26, 2017 114 (52) 13667-13672; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1714249114
- You have accessKinetics of drug–ribosome interactions defines the cidality of macrolide antibioticsMaxim S. Svetlov, Nora Vázquez-Laslop, and Alexander S. MankinPNAS December 26, 2017 114 (52) 13673-13678; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1717168115
Biophysics and Computational Biology
- Open AccessMolecular mechanism for the subversion of the retromer coat by the Legionella effector RidLMiguel Romano-Moreno, Adriana L. Rojas, Chad D. Williamson, David C. Gershlick, María Lucas, Michail N. Isupov, Juan S. Bonifacino, Matthias P. Machner, and Aitor HierroPNAS December 26, 2017 114 (52) E11151-E11160; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1715361115
- You have accessSingle-cell analysis resolves the cell state transition and signaling dynamics associated with melanoma drug-induced resistanceYapeng Su, Wei Wei, Lidia Robert, Min Xue, Jennifer Tsoi, Angel Garcia-Diaz, Blanca Homet Moreno, Jungwoo Kim, Rachel H. Ng, Jihoon W. Lee, Richard C. Koya, Begonya Comin-Anduix, Thomas G. Graeber, Antoni Ribas, and James R. HeathPNAS December 26, 2017 114 (52) 13679-13684; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1712064115
- You have accessStructure-based prediction of ligand–protein interactions on a genome-wide scaleHowook Hwang, Fabian Dey, Donald Petrey, and Barry HonigPNAS December 26, 2017 114 (52) 13685-13690; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1705381114
- You have accessThree tRNAs on the ribosome slow translation elongationJunhong Choi and Joseph D. PuglisiPNAS December 26, 2017 114 (52) 13691-13696; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1719592115
- You have accessPredicting glycosaminoglycan surface protein interactions and implications for studying axonal growthAdam R. Griffith, Claude J. Rogers, Gregory M. Miller, Ravinder Abrol, Linda C. Hsieh-Wilson, and William A. Goddard IIIPNAS December 26, 2017 114 (52) 13697-13702; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1715093115
- You have accessStructural studies of Chikungunya virus maturation
- From the Cover
Moh Lan Yap, Thomas Klose, Akane Urakami, S. Saif Hasan, Wataru Akahata, and Michael G. RossmannPNAS December 26, 2017 114 (52) 13703-13707; published ahead of print December 4, 2017. https://doi.org/10.1073/pnas.1713166114 - You have accessStructural changes of tailless bacteriophage ΦX174 during penetration of bacterial cell wallsYingyuan Sun, Aaron P. Roznowski, Joshua M. Tokuda, Thomas Klose, Alexander Mauney, Lois Pollack, Bentley A. Fane, and Michael G. RossmannPNAS December 26, 2017 114 (52) 13708-13713; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1716614114
- Open AccessNetwork analysis identifies chromosome intermingling regions as regulatory hotspots for transcriptionAnastasiya Belyaeva, Saradha Venkatachalapathy, Mallika Nagarajan, G. V. Shivashankar, and Caroline UhlerPNAS December 26, 2017 114 (52) 13714-13719; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1708028115
Cell Biology
- You have accessCytoplasmic Cl− couples membrane remodeling to epithelial morphogenesisMu He, Wenlei Ye, Won-Jing Wang, Eirish S. Sison, Yuh Nung Jan, and Lily Yeh JanPNAS December 26, 2017 114 (52) E11161-E11169; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1714448115
- Open AccessDaple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundlesKimberly Siletti, Basile Tarchini, and A. J. HudspethPNAS December 26, 2017 114 (52) E11170-E11179; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1716522115
- You have accessArchitecture of the human PI4KIIIα lipid kinase complexJoshua A. Lees, Yixiao Zhang, Michael S. Oh, Curtis M. Schauder, Xiaoling Yu, Jeremy M. Baskin, Kerry Dobbs, Luigi D. Notarangelo, Pietro De Camilli, Thomas Walz, and Karin M. ReinischPNAS December 26, 2017 114 (52) 13720-13725; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1718471115
- Open AccessProteasomes tether to two distinct sites at the nuclear pore complexSahradha Albert, Miroslava Schaffer, Florian Beck, Shyamal Mosalaganti, Shoh Asano, Henry F. Thomas, Jürgen M. Plitzko, Martin Beck, Wolfgang Baumeister, and Benjamin D. EngelPNAS December 26, 2017 114 (52) 13726-13731; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1716305114
- You have accessO-GlcNAcylation destabilizes the active tetrameric PKM2 to promote the Warburg effectYang Wang, Jia Liu, Xin Jin, Dapeng Zhang, Dongxue Li, Fengqi Hao, Yunpeng Feng, Shan Gu, Fanlin Meng, Miaomiao Tian, Yi Zheng, Ling Xin, Xinbo Zhang, Xue Han, L. Aravind, and Min WeiPNAS December 26, 2017 114 (52) 13732-13737; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1704145115
- You have accessA small-molecule activator of kinesin-1 drives remodeling of the microtubule network
- From the Cover
Thomas S. Randall, Yan Y. Yip, Daynea J. Wallock-Richards, Karin Pfisterer, Anneri Sanger, Weronika Ficek, Roberto A. Steiner, Andrew J. Beavil, Maddy Parsons, and Mark P. DoddingPNAS December 26, 2017 114 (52) 13738-13743; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1715115115
Developmental Biology
- You have accessRegulatory networks specifying cortical interneurons from human embryonic stem cells reveal roles for CHD2 in interneuron developmentKesavan Meganathan, Emily M. A. Lewis, Paul Gontarz, Shaopeng Liu, Edouard G. Stanley, Andrew G. Elefanty, James E. Huettner, Bo Zhang, and Kristen L. KrollPNAS December 26, 2017 114 (52) E11180-E11189; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1712365115
- You have accessTroy/TNFRSF19 marks epithelial progenitor cells during mouse kidney development that continue to contribute to turnover in adult kidneyFrans Schutgens, Maarten B. Rookmaaker, Francis Blokzijl, Ruben van Boxtel, Robert Vries, Edwin Cuppen, Marianne C. Verhaar, and Hans CleversPNAS December 26, 2017 114 (52) E11190-E11198; published ahead of print December 13, 2017. https://doi.org/10.1073/pnas.1714145115
- Open AccessMachine learning shows association between genetic variability in PPARG and cerebral connectivity in preterm infantsMichelle L. Krishnan, Zi Wang, Paul Aljabar, Gareth Ball, Ghazala Mirza, Alka Saxena, Serena J. Counsell, Joseph V. Hajnal, Giovanni Montana, and A. David EdwardsPNAS December 26, 2017 114 (52) 13744-13749; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1704907114
Ecology
- Open AccessZooplankton can actively adjust their motility to turbulent flowFrançois-Gaël Michalec, Itzhak Fouxon, Sami Souissi, and Markus HolznerPNAS December 26, 2017 114 (52) E11199-E11207; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1708888114
- You have accessHuman presence diminishes the importance of climate in driving fire activity across the United StatesAlexandra D. Syphard, Jon E. Keeley, Anne H. Pfaff, and Ken FerschweilerPNAS December 26, 2017 114 (52) 13750-13755; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1713885114
- You have accessNaturalization of European plants on other continents: The role of donor habitatsVeronika Kalusová, Milan Chytrý, Mark van Kleunen, Ladislav Mucina, Wayne Dawson, Franz Essl, Holger Kreft, Jan Pergl, Patrick Weigelt, Marten Winter, and Petr PyšekPNAS December 26, 2017 114 (52) 13756-13761; published ahead of print December 4, 2017. https://doi.org/10.1073/pnas.1705487114
- Open AccessCritical dynamics in population vaccinating behaviorA. Demetri Pananos, Thomas M. Bury, Clara Wang, Justin Schonfeld, Sharada P. Mohanty, Brendan Nyhan, Marcel Salathé, and Chris T. BauchPNAS December 26, 2017 114 (52) 13762-13767; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1704093114
Evolution
- You have accessDispersal limitation promotes the diversification of the mammalian gut microbiotaAndrew H. Moeller, Taichi A. Suzuki, Dana Lin, Eileen A. Lacey, Samuel K. Wasser, and Michael W. NachmanPNAS December 26, 2017 114 (52) 13768-13773; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1700122114
- Open AccessResource limitation prevents the emergence of drug resistance by intensifying within-host competitionNina Wale, Derek G. Sim, Matthew J. Jones, Rahel Salathe, Troy Day, and Andrew F. ReadPNAS December 26, 2017 114 (52) 13774-13779; published ahead of print December 12, 2017. https://doi.org/10.1073/pnas.1715874115
Genetics
- You have accessSer7 of RNAPII-CTD facilitates heterochromatin formation by linking ncRNA to RNAiTakuya Kajitani, Hiroaki Kato, Yuji Chikashige, Chihiro Tsutsumi, Yasushi Hiraoka, Hiroshi Kimura, Yasuyuki Ohkawa, Chikashi Obuse, Damien Hermand, and Yota MurakamiPNAS December 26, 2017 114 (52) E11208-E11217; published ahead of print December 13, 2017. https://doi.org/10.1073/pnas.1714579115
- You have accessEffects of mutation and selection on plasticity of a promoter activity in Saccharomyces cerevisiaeFabien Duveau, David C. Yuan, Brian P. H. Metzger, Andrea Hodgins-Davis, and Patricia J. WittkoppPNAS December 26, 2017 114 (52) E11218-E11227; published ahead of print December 19, 2017. https://doi.org/10.1073/pnas.1713960115
- You have accessEpigenetic control of pheromone MAPK signaling determines sexual fecundity in Candida albicansChristine M. Scaduto, Shail Kabrawala, Gregory J. Thomson, William Scheving, Andy Ly, Matthew Z. Anderson, Malcolm Whiteway, and Richard J. BennettPNAS December 26, 2017 114 (52) 13780-13785; published ahead of print December 18, 2017. https://doi.org/10.1073/pnas.1711141115
Immunology and Inflammation
- You have accessATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4+ T cell pathogenicity during CNS inflammationChristian W. Keller, Christina Sina, Monika B. Kotur, Giulia Ramelli, Sarah Mundt, Isaak Quast, Laure-Anne Ligeon, Patrick Weber, Burkhard Becher, Christian Münz, and Jan D. LünemannPNAS December 26, 2017 114 (52) E11228-E11237; published ahead of print December 12, 2017. https://doi.org/10.1073/pnas.1713664114
- You have accessCytokine signaling through Drosophila Mthl10 ties lifespan to environmental stressEui Jae Sung, Masasuke Ryuda, Hitoshi Matsumoto, Outa Uryu, Masanori Ochiai, Molly E. Cook, Na Young Yi, Huanchen Wang, James W. Putney, Gary S. Bird, Stephen B. Shears, and Yoichi HayakawaPNAS December 26, 2017 114 (52) 13786-13791; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1712453115
Medical Sciences
- You have accessSclerostin influences body composition by regulating catabolic and anabolic metabolism in adipocytesSoohyun P. Kim, Julie L. Frey, Zhu Li, Priyanka Kushwaha, Meredith L. Zoch, Ryan E. Tomlinson, Hao Da, Susan Aja, Hye Lim Noh, Jason K. Kim, Mehboob A. Hussain, Daniel L. J. Thorek, Michael J. Wolfgang, and Ryan C. RiddlePNAS December 26, 2017 114 (52) E11238-E11247; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1707876115
- You have accessClinical, genetic, and structural basis of apparent mineralocorticoid excess due to 11β-hydroxysteroid dehydrogenase type 2 deficiencyMabel Yau, Shozeb Haider, Ahmed Khattab, Chen Ling, Mehr Mathew, Samir Zaidi, Madison Bloch, Monica Patel, Sinead Ewert, Wafa Abdullah, Aysenur Toygar, Vitalii Mudryi, Maryam Al Badi, Mouch Alzubdi, Robert C. Wilson, Hanan Said Al Azkawi, Hatice Nur Ozdemir, Wahid Abu-Amer, Jozef Hertecant, Maryam Razzaghy-Azar, John W. Funder, Aisha Al Senani, Li Sun, Se-Min Kim, Tony Yuen, Mone Zaidi, and Maria I. NewPNAS December 26, 2017 114 (52) E11248-E11256; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1716621115
- Open AccessHuman genetic variation alters CRISPR-Cas9 on- and off-targeting specificity at therapeutically implicated lociSamuel Lessard, Laurent Francioli, Jessica Alfoldi, Jean-Claude Tardif, Patrick T. Ellinor, Daniel G. MacArthur, Guillaume Lettre, Stuart H. Orkin, and Matthew C. CanverPNAS December 26, 2017 114 (52) E11257-E11266; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1714640114
- Open AccessImpact of insecticide resistance in Anopheles arabiensis on malaria incidence and prevalence in Sudan and the costs of mitigationHmooda Toto Kafy, Bashir Adam Ismail, Abraham Peter Mnzava, Jonathan Lines, Mogahid Shiekh Eldin Abdin, Jihad Sulieman Eltaher, Anuar Osman Banaga, Philippa West, John Bradley, Jackie Cook, Brent Thomas, Krishanthi Subramaniam, Janet Hemingway, Tessa Bellamy Knox, Elfatih M. Malik, Joshua O. Yukich, Martin James Donnelly, and Immo KleinschmidtPNAS December 26, 2017 114 (52) E11267-E11275; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1713814114
- Open AccessIdentification of cancer genes that are independent of dominant proliferation and lineage programsLaura M. Selfors, Daniel G. Stover, Isaac S. Harris, Joan S. Brugge, and Jonathan L. ColoffPNAS December 26, 2017 114 (52) E11276-E11284; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1714877115
- Open AccessMechanism by which arylamine N-acetyltransferase 1 ablation causes insulin resistance in miceJoão Paulo Camporez, Yongliang Wang, Kasper Faarkrog, Natsasi Chukijrungroat, Kitt Falk Petersen, and Gerald I. ShulmanPNAS December 26, 2017 114 (52) E11285-E11292; published ahead of print December 13, 2017. https://doi.org/10.1073/pnas.1716990115
- Open AccessInterferon-beta represses cancer stem cell properties in triple-negative breast cancerMary R. Doherty, HyeonJoo Cheon, Damian J. Junk, Shaveta Vinayak, Vinay Varadan, Melinda L. Telli, James M. Ford, George R. Stark, and Mark W. JacksonPNAS December 26, 2017 114 (52) 13792-13797; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1713728114
- You have accessEarly endosome as a pathogenic target for antiphosphatidylethanolamine antibodiesSongwang Hou, Heike Fölsch, Ke Ke, Joan Cook Mills, Rosalind Ramsey-Goldman, and Ming ZhaoPNAS December 26, 2017 114 (52) 13798-13803; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1714027115
- You have accessObligatory role of hypothalamic neuroestradiol during the estrogen-induced LH surge in female ovariectomized rhesus monkeysBrian P. Kenealy, Kim L. Keen, James P. Garcia, Lucille K. Kohlenberg, and Ei TerasawaPNAS December 26, 2017 114 (52) 13804-13809; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1716097115
Neuroscience
- Open AccessBrain urea increase is an early Huntington’s disease pathogenic event observed in a prodromal transgenic sheep model and HD casesRenee R. Handley, Suzanne J. Reid, Rudiger Brauning, Paul Maclean, Emily R. Mears, Imche Fourie, Stefano Patassini, Garth J. S. Cooper, Skye R. Rudiger, Clive J. McLaughlan, Paul J. Verma, James F. Gusella, Marcy E. MacDonald, Henry J. Waldvogel, C. Simon Bawden, Richard L. M. Faull, and Russell G. SnellPNAS December 26, 2017 114 (52) E11293-E11302; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1711243115
- Open AccessA transient dopamine signal encodes subjective value and causally influences demand in an economic context
- From the Cover
Scott A. Schelp, Katherine J. Pultorak, Dylan R. Rakowski, Devan M. Gomez, Gregory Krzystyniak, Raibatak Das, and Erik B. OlesonPNAS December 26, 2017 114 (52) E11303-E11312; published ahead of print November 6, 2017. https://doi.org/10.1073/pnas.1706969114 - Open AccessFKBP12 contributes to α-synuclein toxicity by regulating the calcineurin-dependent phosphoproteomeGabriela Caraveo, Martin Soste, Valentina Cappelleti, Saranna Fanning, Damian B. van Rossum, Luke Whitesell, Yanmei Huang, Chee Yeun Chung, Valeriya Baru, Sofia Zaichick, Paola Picotti, and Susan LindquistPNAS December 26, 2017 114 (52) E11313-E11322; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1711926115
- You have accessBeta oscillations reflect supramodal information during perceptual judgmentSaskia Haegens, José Vergara, Román Rossi-Pool, Luis Lemus, and Ranulfo RomoPNAS December 26, 2017 114 (52) 13810-13815; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1714633115
- You have accessAppetite suppressive role of medial septal glutamatergic neuronsPatrick Sweeney, Changhong Li, and Yunlei YangPNAS December 26, 2017 114 (52) 13816-13821; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1707228114
Physiology
- You have accessNoncanonical thyroid hormone signaling mediates cardiometabolic effects in vivoG. Sebastian Hönes, Helena Rakov, John Logan, Xiao-Hui Liao, Eugenie Werbenko, Andrea S. Pollard, Stine M. Præstholm, Majken S. Siersbæk, Eddy Rijntjes, Janina Gassen, Sören Latteyer, Kathrin Engels, Karl-Heinz Strucksberg, Petra Kleinbongard, Denise Zwanziger, Jan Rozman, Valerie Gailus-Durner, Helmut Fuchs, Martin Hrabe de Angelis, Ludger Klein-Hitpass, Josef Köhrle, David L. Armstrong, Lars Grøntved, J. H. Duncan Bassett, Graham R. Williams, Samuel Refetoff, Dagmar Führer, and Lars C. MoellerPNAS December 26, 2017 114 (52) E11323-E11332; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1706801115
- You have accessDe novo reconstitution reveals the proteins required for skeletal muscle voltage-induced Ca2+ releaseStefano Perni, Manuela Lavorato, and Kurt G. BeamPNAS December 26, 2017 114 (52) 13822-13827; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1716461115
- You have accessAccelerating fishes increase propulsive efficiency by modulating vortex ring geometryOtar Akanyeti, Joy Putney, Yuzo R. Yanagitsuru, George V. Lauder, William J. Stewart, and James C. LiaoPNAS December 26, 2017 114 (52) 13828-13833; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1705968115
Plant Biology
- You have accessHow reduced excitonic coupling enhances light harvesting in the main photosynthetic antennae of diatomsTjaart P. J. Krüger, Pavel Malý, Maxime T. A. Alexandre, Tomáš Mančal, Claudia Büchel, and Rienk van GrondellePNAS December 26, 2017 114 (52) E11063-E11071; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1714656115
- You have accessEthylene promotes root hair growth through coordinated EIN3/EIL1 and RHD6/RSL1 activity in ArabidopsisYing Feng, Ping Xu, Bosheng Li, Pengpeng Li, Xing Wen, Fengying An, Yan Gong, Yi Xin, Ziqiang Zhu, Yichuan Wang, and Hongwei GuoPNAS December 26, 2017 114 (52) 13834-13839; published ahead of print December 12, 2017. https://doi.org/10.1073/pnas.1711723115
Psychological and Cognitive Sciences
- You have accessPerception and misperception of surface opacityPhillip J. Marlow, Juno Kim, and Barton L. AndersonPNAS December 26, 2017 114 (52) 13840-13845; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1711416115
Sustainability Science
- You have accessHuman presence diminishes the importance of climate in driving fire activity across the United StatesAlexandra D. Syphard, Jon E. Keeley, Anne H. Pfaff, and Ken FerschweilerPNAS December 26, 2017 114 (52) 13750-13755; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1713885114
Corrections (Online Only)
- You have accessCorrection for Waldrop, News Feature: The genuine problem of fake newsPNAS December 26, 2017 114 (52) E11333; published ahead of print December 18, 2017. https://doi.org/10.1073/pnas.1721073115
- You have accessCorrection for Roehr, Core Concept: Tissue resident memory cells emerging as key player in health and diseasePNAS December 26, 2017 114 (52) E11334; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1720330115
- You have accessCorrection for Possner and Caldeira, Geophysical potential for wind energy over the open oceansPNAS December 26, 2017 114 (52) E11335; published ahead of print December 11, 2017. https://doi.org/10.1073/pnas.1720315115
Retraction (Online Only)
- You have accessRetraction for Ottmann et al., Long-term aggregation of larval fish siblings during dispersal along an open coastPNAS December 26, 2017 114 (52) E11336; published ahead of print December 18, 2017. https://doi.org/10.1073/pnas.1720656115
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