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Table of Contents
March 20, 2018; vol. 115 no. 12
This Week in PNAS
Letters (Online Only)
- You have accessAnthropogenic enrichment of mercury greater than that of vanadiumNoelle E. SelinPNAS March 20, 2018 115 (12) E2666-E2667; first published March 6, 2018. https://doi.org/10.1073/pnas.1722284115
- You have accessReply to Selin: Human impacts on the atmospheric burden of trace metalsWilliam H. Schlesinger, Emily M. Klein, and Avner VengoshPNAS March 20, 2018 115 (12) E2668; first published March 6, 2018. https://doi.org/10.1073/pnas.1800958115
See companion article:
- Global biogeochemical cycle of vanadium- Dec 11, 2017
- You have accessHydrologic regulation of plant rooting depth: Breakthrough or observational conundrum?Alain Pierret and Guillaume LacombePNAS March 20, 2018 115 (12) E2669-E2670; first published February 27, 2018. https://doi.org/10.1073/pnas.1801721115
- You have accessReply to Pierret and Lacombe: Global controls on maximum rooting depths remain importantYing Fan, Gonzalo Miguez-Macho, Esteban G. Jobbágy, Robert B. Jackson, and Carlos Otero-CasalPNAS March 20, 2018 115 (12) E2671-E2672; first published February 27, 2018. https://doi.org/10.1073/pnas.1801899115
See companion article:
- Hydrologic regulation of plant rooting depth- Sep 18, 2017
- You have accessDefaunation shadow on mutualistic interactionsRaul Costa-Pereira, Christine Lucas, Marcelo Crossa, Jill T. Anderson, Bianca Weiss Albuquerque, Eurizângela P. Dary, Maria T. F. Piedade, Layon O. Demarchi, Elizabeth R. Rebouças, Gilvan da S. Costa, Mauro Galetti, and Sandra Bibiana CorreaPNAS March 20, 2018 115 (12) E2673-E2675; first published March 7, 2018. https://doi.org/10.1073/pnas.1801106115
Opinion
Leading scientists discuss current issues.
- You have accessOpinion: How to tackle the childcare–conference conundrum
- Front Matter
Rebecca M. Calisi and a Working Group of Mothers in SciencePNAS March 20, 2018 115 (12) 2845-2849; first published March 5, 2018. https://doi.org/10.1073/pnas.1803153115
PNAS Plus Significance Statements
Brief statements written by the authors about the significance of their papers.
Perspective
- You have accessHuman aging and disease: Lessons from age-related macular degenerationJennings Luu and Krzysztof PalczewskiPNAS March 20, 2018 115 (12) 2866-2872; first published February 26, 2018. https://doi.org/10.1073/pnas.1721033115
Physical Sciences
Applied Physical Sciences
- Open AccessStrain-induced high-temperature perovskite ferromagnetic insulatorDechao Meng, Hongli Guo, Zhangzhang Cui, Chao Ma, Jin Zhao, Jiangbo Lu, Hui Xu, Zhicheng Wang, Xiang Hu, Zhengping Fu, Ranran Peng, Jinghua Guo, Xiaofang Zhai, Gail J. Brown, Randy Knize, and Yalin LuPNAS March 20, 2018 115 (12) 2873-2877; first published March 5, 2018. https://doi.org/10.1073/pnas.1707817115
- You have accessManipulating thermal emission with spatially static fluctuating fields in arbitrarily shaped epsilon-near-zero bodiesIñigo Liberal and Nader EnghetaPNAS March 20, 2018 115 (12) 2878-2883; first published March 5, 2018. https://doi.org/10.1073/pnas.1718264115
- Open AccessBifurcation-enhanced ultrahigh sensitivity of a buckled cantileverSangmin An, Bongsu Kim, Soyoung Kwon, Geol Moon, Manhee Lee, and Wonho JhePNAS March 20, 2018 115 (12) 2884-2889; first published March 6, 2018. https://doi.org/10.1073/pnas.1716067115
Biophysics and Computational Biology
- You have accessNoninvasive detection of macrophage activation with single-cell resolution through machine learningNicolas Pavillon, Alison J. Hobro, Shizuo Akira, and Nicholas I. SmithPNAS March 20, 2018 115 (12) E2676-E2685; first published March 6, 2018. https://doi.org/10.1073/pnas.1711872115
- You have accessMatching material and cellular timescales maximizes cell spreading on viscoelastic substratesZe Gong, Spencer E. Szczesny, Steven R. Caliari, Elisabeth E. Charrier, Ovijit Chaudhuri, Xuan Cao, Yuan Lin, Robert L. Mauck, Paul A. Janmey, Jason A. Burdick, and Vivek B. ShenoyPNAS March 20, 2018 115 (12) E2686-E2695; first published March 5, 2018. https://doi.org/10.1073/pnas.1716620115
- You have accessAllostery revealed within lipid binding events to membrane proteinsJohn W. Patrick, Christopher D. Boone, Wen Liu, Gloria M. Conover, Yang Liu, Xiao Cong, and Arthur LaganowskyPNAS March 20, 2018 115 (12) 2976-2981; first published March 5, 2018. https://doi.org/10.1073/pnas.1719813115
- You have accessCrystal structure of bacterial succinate:quinone oxidoreductase flavoprotein SdhA in complex with its assembly factor SdhEMegan J. Maher, Anuradha S. Herath, Saumya R. Udagedara, David A. Dougan, and Kaye N. TruscottPNAS March 20, 2018 115 (12) 2982-2987; first published March 7, 2018. https://doi.org/10.1073/pnas.1800195115
- You have accessDynamic patterns of cortical expansion during folding of the preterm human brainKara E. Garcia, Emma C. Robinson, Dimitrios Alexopoulos, Donna L. Dierker, Matthew F. Glasser, Timothy S. Coalson, Cynthia M. Ortinau, Daniel Rueckert, Larry A. Taber, David C. Van Essen, Cynthia E. Rogers, Christopher D. Smyser, and Philip V. BaylyPNAS March 20, 2018 115 (12) 3156-3161; first published March 5, 2018. https://doi.org/10.1073/pnas.1715451115
Chemistry
- You have accessSurface chemical heterogeneity modulates silica surface hydrationAlex M. Schrader, Jacob I. Monroe, Ryan Sheil, Howard A. Dobbs, Timothy J. Keller, Yuanxin Li, Sheetal Jain, M. Scott Shell, Jacob N. Israelachvili, and Songi HanPNAS March 20, 2018 115 (12) 2890-2895; first published March 5, 2018. https://doi.org/10.1073/pnas.1722263115
- You have accessChirality-controlled spontaneous twisting of crystals due to thermal topochemical reactionRishika Rai, Baiju P. Krishnan, and Kana M. SureshanPNAS March 20, 2018 115 (12) 2896-2901; first published March 5, 2018. https://doi.org/10.1073/pnas.1718965115
- You have accessStable iridium dinuclear heterogeneous catalysts supported on metal-oxide substrate for solar water oxidationYanyan Zhao, Ke R. Yang, Zechao Wang, Xingxu Yan, Sufeng Cao, Yifan Ye, Qi Dong, Xizi Zhang, James E. Thorne, Lei Jin, Kelly L. Materna, Antonios Trimpalis, Hongye Bai, Sirine C. Fakra, Xiaoyan Zhong, Peng Wang, Xiaoqing Pan, Jinghua Guo, Maria Flytzani-Stephanopoulos, Gary W. Brudvig, Victor S. Batista, and Dunwei WangPNAS March 20, 2018 115 (12) 2902-2907; first published March 5, 2018. https://doi.org/10.1073/pnas.1722137115
- You have accessMechanism of the G-protein mimetic nanobody binding to a muscarinic G-protein-coupled receptorYinglong Miao and J. Andrew McCammonPNAS March 20, 2018 115 (12) 3036-3041; first published March 5, 2018. https://doi.org/10.1073/pnas.1800756115
Computer Sciences
- You have accessSusceptibility of brain atrophy to TRIB3 in Alzheimer’s disease, evidence from functional prioritization in imaging geneticsMarco Lorenzi, Andre Altmann, Boris Gutman, Selina Wray, Charles Arber, Derrek P. Hibar, Neda Jahanshad, Jonathan M. Schott, Daniel C. Alexander, Paul M. Thompson, Sebastien Ourselin, and for the Alzheimer’s Disease Neuroimaging InitiativePNAS March 20, 2018 115 (12) 3162-3167; first published March 6, 2018. https://doi.org/10.1073/pnas.1706100115
Earth, Atmospheric, and Planetary Sciences
- You have accessDiscovery of a hexagonal ultradense hydrous phase in (Fe,Al)OOHLi Zhang, Hongsheng Yuan, Yue Meng, and Ho-kwang MaoPNAS March 20, 2018 115 (12) 2908-2911; first published March 5, 2018. https://doi.org/10.1073/pnas.1720510115
- You have accessLong-term urban carbon dioxide observations reveal spatial and temporal dynamics related to urban characteristics and growthLogan E. Mitchell, John C. Lin, David R. Bowling, Diane E. Pataki, Courtenay Strong, Andrew J. Schauer, Ryan Bares, Susan E. Bush, Britton B. Stephens, Daniel Mendoza, Derek Mallia, Lacey Holland, Kevin R. Gurney, and James R. EhleringerPNAS March 20, 2018 115 (12) 2912-2917; first published March 5, 2018. https://doi.org/10.1073/pnas.1702393115
- You have accessUranium isotope evidence for two episodes of deoxygenation during Oceanic Anoxic Event 2Matthew O. Clarkson, Claudine H. Stirling, Hugh C. Jenkyns, Alexander J. Dickson, Don Porcelli, Christopher M. Moy, Philip A. E. Pogge von Strandmann, Ilsa R. Cooke, and Timothy M. LentonPNAS March 20, 2018 115 (12) 2918-2923; first published March 5, 2018. https://doi.org/10.1073/pnas.1715278115
- You have accessBiomass smoke from southern Africa can significantly enhance the brightness of stratocumulus over the southeastern Atlantic OceanZheng Lu, Xiaohong Liu, Zhibo Zhang, Chun Zhao, Kerry Meyer, Chamara Rajapakshe, Chenglai Wu, Zhifeng Yang, and Joyce E. PennerPNAS March 20, 2018 115 (12) 2924-2929; first published March 5, 2018. https://doi.org/10.1073/pnas.1713703115
- You have accessAcceleration of tropical cyclogenesis by self-aggregation feedbacksCaroline J. Muller and David M. RompsPNAS March 20, 2018 115 (12) 2930-2935; first published March 5, 2018. https://doi.org/10.1073/pnas.1719967115
Engineering
- You have accessStructurally modulated codelivery of siRNA and Argonaute 2 for enhanced RNA interference
- From the Cover
Jiahe Li, Connie Wu, Wade Wang, Yanpu He, Elad Elkayam, Leemor Joshua-Tor, and Paula T. HammondPNAS March 20, 2018 115 (12) E2696-E2705; first published February 5, 2018. https://doi.org/10.1073/pnas.1719565115See companion article:
- Toward new design principles for superior gene silencing- Mar 16, 2018
- You have accessLayered dynamic regulation for improving metabolic pathway productivity in Escherichia coliStephanie J. Doong, Apoorv Gupta, and Kristala L. J. PratherPNAS March 20, 2018 115 (12) 2964-2969; first published March 5, 2018. https://doi.org/10.1073/pnas.1716920115
Physics
- You have accessPhysical and geometric constraints shape the labyrinth-like nasal cavityDavid Zwicker, Rodolfo Ostilla-Mónico, Daniel E. Lieberman, and Michael P. BrennerPNAS March 20, 2018 115 (12) 2936-2941; first published March 5, 2018. https://doi.org/10.1073/pnas.1714795115
Sustainability Science
- Open AccessMeasuring the potential for sustainable intensification of aquaculture in Bangladesh using life cycle assessmentPatrik John Gustav Henriksson, Ben Belton, Khondker Murshed-e- Jahan, and Andreu RicoPNAS March 20, 2018 115 (12) 2958-2963; first published March 5, 2018. https://doi.org/10.1073/pnas.1716530115
Social Sciences
Economic Sciences
- Open AccessBrief history of US debt limits before 1939George J. Hall and Thomas J. SargentPNAS March 20, 2018 115 (12) 2942-2945; first published March 5, 2018. https://doi.org/10.1073/pnas.1719687115
Environmental Sciences
- You have accessModeling environmentally mediated rotavirus transmission: The role of temperature and hydrologic factorsAlicia N. M. Kraay, Andrew F. Brouwer, Nan Lin, Philip A. Collender, Justin V. Remais, and Joseph N. S. EisenbergPNAS March 20, 2018 115 (12) E2782-E2790; first published March 1, 2018. https://doi.org/10.1073/pnas.1719579115
- Open AccessCitywide cluster randomized trial to restore blighted vacant land and its effects on violence, crime, and fearCharles C. Branas, Eugenia South, Michelle C. Kondo, Bernadette C. Hohl, Philippe Bourgois, Douglas J. Wiebe, and John M. MacDonaldPNAS March 20, 2018 115 (12) 2946-2951; first published February 26, 2018. https://doi.org/10.1073/pnas.1718503115
Social Sciences
- You have accessLow agreement among reviewers evaluating the same NIH grant applicationsElizabeth L. Pier, Markus Brauer, Amarette Filut, Anna Kaatz, Joshua Raclaw, Mitchell J. Nathan, Cecilia E. Ford, and Molly CarnesPNAS March 20, 2018 115 (12) 2952-2957; first published March 5, 2018. https://doi.org/10.1073/pnas.1714379115
Biological Sciences
Agricultural Sciences
- Open AccessMeasuring the potential for sustainable intensification of aquaculture in Bangladesh using life cycle assessmentPatrik John Gustav Henriksson, Ben Belton, Khondker Murshed-e- Jahan, and Andreu RicoPNAS March 20, 2018 115 (12) 2958-2963; first published March 5, 2018. https://doi.org/10.1073/pnas.1716530115
Applied Biological Sciences
- You have accessStructurally modulated codelivery of siRNA and Argonaute 2 for enhanced RNA interference
- From the Cover
Jiahe Li, Connie Wu, Wade Wang, Yanpu He, Elad Elkayam, Leemor Joshua-Tor, and Paula T. HammondPNAS March 20, 2018 115 (12) E2696-E2705; first published February 5, 2018. https://doi.org/10.1073/pnas.1719565115See companion article:
- Toward new design principles for superior gene silencing- Mar 16, 2018
- You have accessLayered dynamic regulation for improving metabolic pathway productivity in Escherichia coliStephanie J. Doong, Apoorv Gupta, and Kristala L. J. PratherPNAS March 20, 2018 115 (12) 2964-2969; first published March 5, 2018. https://doi.org/10.1073/pnas.1716920115
- Open AccessToward engineering E. coli with an autoregulatory system for lignin valorizationWeihua Wu, Fang Liu, and Seema SinghPNAS March 20, 2018 115 (12) 2970-2975; first published March 2, 2018. https://doi.org/10.1073/pnas.1720129115
Biochemistry
- Open AccessStructural basis for the role of serine-rich repeat proteins from Lactobacillus reuteri in gut microbe–host interactionsSaannya Sequeira, Devon Kavanaugh, Donald A. MacKenzie, Tanja Šuligoj, Samuel Walpole, Charlotte Leclaire, A. Patrick Gunning, Dimitrios Latousakis, William G. T. Willats, Jesus Angulo, Changjiang Dong, and Nathalie JugePNAS March 20, 2018 115 (12) E2706-E2715; first published March 5, 2018. https://doi.org/10.1073/pnas.1715016115
- You have accessN-terminal arginylation generates a bimodal degron that modulates autophagic proteolysisYoung Dong Yoo, Su Ran Mun, Chang Hoon Ji, Ki Woon Sung, Keum Young Kang, Ah Jung Heo, Su Hyun Lee, Jee Young An, Joonsung Hwang, Xiang-Qun Xie, Aaron Ciechanover, Bo Yeon Kim, and Yong Tae KwonPNAS March 20, 2018 115 (12) E2716-E2724; first published March 5, 2018. https://doi.org/10.1073/pnas.1719110115
- You have accessLiver X receptor β regulates the development of the dentate gyrus and autistic-like behavior in the mouseYulong Cai, Xiaotong Tang, Xi Chen, Xin Li, Ying Wang, Xiaohang Bao, Lian Wang, Dayu Sun, Jinghui Zhao, Yan Xing, Margaret Warner, Haiwei Xu, Jan-Åke Gustafsson, and Xiaotang FanPNAS March 20, 2018 115 (12) E2725-E2733; first published March 5, 2018. https://doi.org/10.1073/pnas.1800184115
- You have accessdCas9-targeted locus-specific protein isolation method identifies histone gene regulatorsChiahao Tsui, Carla Inouye, Michaella Levy, Andrew Lu, Laurence Florens, Michael P. Washburn, and Robert TjianPNAS March 20, 2018 115 (12) E2734-E2741; first published March 5, 2018. https://doi.org/10.1073/pnas.1718844115
- You have accessAllostery revealed within lipid binding events to membrane proteinsJohn W. Patrick, Christopher D. Boone, Wen Liu, Gloria M. Conover, Yang Liu, Xiao Cong, and Arthur LaganowskyPNAS March 20, 2018 115 (12) 2976-2981; first published March 5, 2018. https://doi.org/10.1073/pnas.1719813115
- You have accessCrystal structure of bacterial succinate:quinone oxidoreductase flavoprotein SdhA in complex with its assembly factor SdhEMegan J. Maher, Anuradha S. Herath, Saumya R. Udagedara, David A. Dougan, and Kaye N. TruscottPNAS March 20, 2018 115 (12) 2982-2987; first published March 7, 2018. https://doi.org/10.1073/pnas.1800195115
- You have accessAssembly of the membrane domain of ATP synthase in human mitochondria
- From the Cover
Jiuya He, Holly C. Ford, Joe Carroll, Corsten Douglas, Evvia Gonzales, Shujing Ding, Ian M. Fearnley, and John E. WalkerPNAS March 20, 2018 115 (12) 2988-2993; first published February 12, 2018. https://doi.org/10.1073/pnas.1722086115See companion article:
- Assembling the mitochondrial ATP synthase- Mar 07, 2018
- You have accessATP-dependent substrate reduction at an [Fe8S9] double-cubane clusterJae-Hun Jeoung and Holger DobbekPNAS March 20, 2018 115 (12) 2994-2999; first published March 5, 2018. https://doi.org/10.1073/pnas.1720489115
- Open AccessModulation of intestinal sulfur assimilation metabolism regulates iron homeostasisBenjamin H. Hudson, Andrew T. Hale, Ryan P. Irving, Shenglan Li, and John D. YorkPNAS March 20, 2018 115 (12) 3000-3005; first published March 5, 2018. https://doi.org/10.1073/pnas.1715302115
- You have accessExploring modular allostery via interchangeable regulatory domainsYifei Fan, Penelope J. Cross, Geoffrey B. Jameson, and Emily J. ParkerPNAS March 20, 2018 115 (12) 3006-3011; first published March 5, 2018. https://doi.org/10.1073/pnas.1717621115
- You have accessMolecular mechanism of ATP versus GTP selectivity of adenylate kinasePer Rogne, Marie Rosselin, Christin Grundström, Christian Hedberg, Uwe H. Sauer, and Magnus Wolf-WatzPNAS March 20, 2018 115 (12) 3012-3017; first published March 5, 2018. https://doi.org/10.1073/pnas.1721508115
- Open AccessDeciphering the reading of the genetic code by near-cognate tRNASandra Blanchet, David Cornu, Isabelle Hatin, Henri Grosjean, Pierre Bertin, and Olivier NamyPNAS March 20, 2018 115 (12) 3018-3023; first published March 5, 2018. https://doi.org/10.1073/pnas.1715578115
- Open AccessConserved in situ arrangement of complex I and III2 in mitochondrial respiratory chain supercomplexes of mammals, yeast, and plantsKaren M. Davies, Thorsten B. Blum, and Werner KühlbrandtPNAS March 20, 2018 115 (12) 3024-3029; first published March 8, 2018. https://doi.org/10.1073/pnas.1720702115
- You have accessEnzymatic reconstitution of ribosomal peptide backbone thioamidationNilkamal Mahanta, Andi Liu, Shihui Dong, Satish K. Nair, and Douglas A. MitchellPNAS March 20, 2018 115 (12) 3030-3035; first published March 5, 2018. https://doi.org/10.1073/pnas.1722324115
Biophysics and Computational Biology
- You have accessMatching material and cellular timescales maximizes cell spreading on viscoelastic substratesZe Gong, Spencer E. Szczesny, Steven R. Caliari, Elisabeth E. Charrier, Ovijit Chaudhuri, Xuan Cao, Yuan Lin, Robert L. Mauck, Paul A. Janmey, Jason A. Burdick, and Vivek B. ShenoyPNAS March 20, 2018 115 (12) E2686-E2695; first published March 5, 2018. https://doi.org/10.1073/pnas.1716620115
- Open AccessConformational transitions of the sodium-dependent sugar transporter, vSGLTAviv Paz, Derek P. Claxton, Jay Prakash Kumar, Kelli Kazmier, Paola Bisignano, Shruti Sharma, Shannon A. Nolte, Terrin M. Liwag, Vinod Nayak, Ernest M. Wright, Michael Grabe, Hassane S. Mchaourab, and Jeff AbramsonPNAS March 20, 2018 115 (12) E2742-E2751; first published March 5, 2018. https://doi.org/10.1073/pnas.1718451115
- You have accessMechanism of the G-protein mimetic nanobody binding to a muscarinic G-protein-coupled receptorYinglong Miao and J. Andrew McCammonPNAS March 20, 2018 115 (12) 3036-3041; first published March 5, 2018. https://doi.org/10.1073/pnas.1800756115
- You have accessStructural basis for the alternating access mechanism of the cation diffusion facilitator YiiPMaria Luisa Lopez-Redondo, Nicolas Coudray, Zhening Zhang, John Alexopoulos, and David L. StokesPNAS March 20, 2018 115 (12) 3042-3047; first published March 5, 2018. https://doi.org/10.1073/pnas.1715051115
- You have accessSolution NMR structure of yeast Rcf1, a protein involved in respiratory supercomplex formationShu Zhou, Pontus Pettersson, Jingjing Huang, Johannes Sjöholm, Dan Sjöstrand, Régis Pomès, Martin Högbom, Peter Brzezinski, Lena Mäler, and Pia ÄdelrothPNAS March 20, 2018 115 (12) 3048-3053; first published March 5, 2018. https://doi.org/10.1073/pnas.1712061115
- You have accessProtein homology model refinement by large-scale energy optimizationHahnbeom Park, Sergey Ovchinnikov, David E. Kim, Frank DiMaio, and David BakerPNAS March 20, 2018 115 (12) 3054-3059; first published March 5, 2018. https://doi.org/10.1073/pnas.1719115115
- You have accessGuanidinium export is the primal function of SMR family transportersAli A. Kermani, Christian B. Macdonald, Roja Gundepudi, and Randy B. StockbridgePNAS March 20, 2018 115 (12) 3060-3065; first published March 5, 2018. https://doi.org/10.1073/pnas.1719187115
- Open AccessSingle-molecule analysis of phospholipid scrambling by TMEM16FRikiya Watanabe, Takaharu Sakuragi, Hiroyuki Noji, and Shigekazu NagataPNAS March 20, 2018 115 (12) 3066-3071; first published March 5, 2018. https://doi.org/10.1073/pnas.1717956115
Cell Biology
- Open AccessBRICHOS domain of Bri2 inhibits islet amyloid polypeptide (IAPP) fibril formation and toxicity in human beta cellsMarie E. Oskarsson, Erik Hermansson, Ye Wang, Nils Welsh, Jenny Presto, Jan Johansson, and Gunilla T. WestermarkPNAS March 20, 2018 115 (12) E2752-E2761; first published March 5, 2018. https://doi.org/10.1073/pnas.1715951115
- Open AccessTransmembrane E3 ligase RNF183 mediates ER stress-induced apoptosis by degrading Bcl-xLYanfang Wu, Xia Li, Junying Jia, Yanpeng Zhang, Jing Li, Zhengmao Zhu, Huaqing Wang, Jie Tang, and Junjie HuPNAS March 20, 2018 115 (12) E2762-E2771; first published March 5, 2018. https://doi.org/10.1073/pnas.1716439115
Developmental Biology
- You have accessMAPK signaling couples SCF-mediated degradation of translational regulators to oocyte meiotic progressionEdyta Kisielnicka, Ryuji Minasaki, and Christian R. EckmannPNAS March 20, 2018 115 (12) E2772-E2781; first published March 1, 2018. https://doi.org/10.1073/pnas.1715439115
Ecology
- You have accessConvergence of marine megafauna movement patterns in coastal and open oceans
- From the Cover
A. M. M. Sequeira, J. P. Rodríguez, V. M. Eguíluz, R. Harcourt, M. Hindell, D. W. Sims, C. M. Duarte, D. P. Costa, J. Fernández-Gracia, L. C. Ferreira, G. C. Hays, M. R. Heupel, M. G. Meekan, A. Aven, F. Bailleul, A. M. M. Baylis, M. L. Berumen, C. D. Braun, J. Burns, M. J. Caley, R. Campbell, R. H. Carmichael, E. Clua, L. D. Einoder, Ari Friedlaender, M. E. Goebel, S. D. Goldsworthy, C. Guinet, J. Gunn, D. Hamer, N. Hammerschlag, M. Hammill, L. A. Hückstädt, N. E. Humphries, M.-A. Lea, A. Lowther, A. Mackay, E. McHuron, J. McKenzie, L. McLeay, C. R. McMahon, K. Mengersen, M. M. C. Muelbert, A. M. Pagano, B. Page, N. Queiroz, P. W. Robinson, S. A. Shaffer, M. Shivji, G. B. Skomal, S. R. Thorrold, S. Villegas-Amtmann, M. Weise, R. Wells, B. Wetherbee, A. Wiebkin, B. Wienecke, and M. ThumsPNAS March 20, 2018 115 (12) 3072-3077; first published February 26, 2018. https://doi.org/10.1073/pnas.1716137115 - Open AccessThe seasonality of nonpolio enteroviruses in the United States: Patterns and driversMargarita Pons-Salort, M. Steven Oberste, Mark A. Pallansch, Glen R. Abedi, Saki Takahashi, Bryan T. Grenfell, and Nicholas C. GrasslyPNAS March 20, 2018 115 (12) 3078-3083; first published March 5, 2018. https://doi.org/10.1073/pnas.1721159115
- You have accessBiogeographical disparity in the functional diversity and redundancy of coralsMike McWilliam, Mia O. Hoogenboom, Andrew H. Baird, Chao-Yang Kuo, Joshua S. Madin, and Terry P. HughesPNAS March 20, 2018 115 (12) 3084-3089; first published March 5, 2018. https://doi.org/10.1073/pnas.1716643115
Environmental Sciences
- You have accessModeling environmentally mediated rotavirus transmission: The role of temperature and hydrologic factorsAlicia N. M. Kraay, Andrew F. Brouwer, Nan Lin, Philip A. Collender, Justin V. Remais, and Joseph N. S. EisenbergPNAS March 20, 2018 115 (12) E2782-E2790; first published March 1, 2018. https://doi.org/10.1073/pnas.1719579115
Evolution
- You have accessAdaptive evolution of genomically recoded Escherichia coli
- From the Cover
Timothy M. Wannier, Aditya M. Kunjapur, Daniel P. Rice, Michael J. McDonald, Michael M. Desai, and George M. ChurchPNAS March 20, 2018 115 (12) 3090-3095; first published February 13, 2018. https://doi.org/10.1073/pnas.1715530115See companion article:
- You have accessGenetic signatures of microbial altruism and cheating in social amoebas in the wildSuegene Noh, Katherine S. Geist, Xiangjun Tian, Joan E. Strassmann, and David C. QuellerPNAS March 20, 2018 115 (12) 3096-3101; first published March 5, 2018. https://doi.org/10.1073/pnas.1720324115
- You have accessVaccination can drive an increase in frequencies of antibiotic resistance among nonvaccine serotypes of Streptococcus pneumoniaeUri Obolski, José Lourenço, Craig Thompson, Robin Thompson, Andrea Gori, and Sunetra GuptaPNAS March 20, 2018 115 (12) 3102-3107; first published March 6, 2018. https://doi.org/10.1073/pnas.1718712115
Genetics
- You have accessMetabolic shift from glycogen to trehalose promotes lifespan and healthspan in Caenorhabditis elegansYonghak Seo, Samuel Kingsley, Griffin Walker, Michelle A. Mondoux, and Heidi A. TissenbaumPNAS March 20, 2018 115 (12) E2791-E2800; first published March 6, 2018. https://doi.org/10.1073/pnas.1714178115
- Open AccessRNAi is a critical determinant of centromere evolution in closely related fungiVikas Yadav, Sheng Sun, R. Blake Billmyre, Bhagya C. Thimmappa, Terrance Shea, Robert Lintner, Guus Bakkeren, Christina A. Cuomo, Joseph Heitman, and Kaustuv SanyalPNAS March 20, 2018 115 (12) 3108-3113; first published March 5, 2018. https://doi.org/10.1073/pnas.1713725115
- You have accessIntermediate filament accumulation can stabilize microtubules in Caenorhabditis elegans motor neuronsNaina Kurup, Yunbo Li, Alexandr Goncharov, and Yishi JinPNAS March 20, 2018 115 (12) 3114-3119; first published March 6, 2018. https://doi.org/10.1073/pnas.1721930115
Immunology and Inflammation
- You have accessNoninvasive detection of macrophage activation with single-cell resolution through machine learningNicolas Pavillon, Alison J. Hobro, Shizuo Akira, and Nicholas I. SmithPNAS March 20, 2018 115 (12) E2676-E2685; first published March 6, 2018. https://doi.org/10.1073/pnas.1711872115
- Open AccessFoxp1 controls mature B cell survival and the development of follicular and B-1 B cellsThomas Patzelt, Selina J. Keppler, Oliver Gorka, Silvia Thoene, Tim Wartewig, Michael Reth, Irmgard Förster, Roland Lang, Maike Buchner, and Jürgen RulandPNAS March 20, 2018 115 (12) 3120-3125; first published March 5, 2018. https://doi.org/10.1073/pnas.1711335115
- You have accessB7-H1 maintains the polyclonal T cell response by protecting dendritic cells from cytotoxic T lymphocyte destructionLing Chen, Takeshi Azuma, Weiwei Yu, Xu Zheng, Liqun Luo, and Lieping ChenPNAS March 20, 2018 115 (12) 3126-3131; first published March 5, 2018. https://doi.org/10.1073/pnas.1722043115
Medical Sciences
- Open AccessMyeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibitionEmanuele Giurisato, Qiuping Xu, Silvia Lonardi, Brian Telfer, Ilaria Russo, Adam Pearson, Katherine G. Finegan, Wenbin Wang, Jinhua Wang, Nathanael S. Gray, William Vermi, Zhengui Xia, and Cathy TournierPNAS March 20, 2018 115 (12) E2801-E2810; first published March 5, 2018. https://doi.org/10.1073/pnas.1707929115
- You have accessPeptides of pHLIP family for targeted intracellular and extracellular delivery of cargo molecules to tumorsLinden C. Wyatt, Anna Moshnikova, Troy Crawford, Donald M. Engelman, Oleg A. Andreev, and Yana K. ReshetnyakPNAS March 20, 2018 115 (12) E2811-E2818; first published March 5, 2018. https://doi.org/10.1073/pnas.1715350115
- Open AccesshMENA is a key regulator in endothelin-1/β-arrestin1–induced invadopodial function and metastatic processFrancesca Di Modugno, Valentina Caprara, Lidia Chellini, Piera Tocci, Francesca Spadaro, Gabriella Ferrandina, Andrea Sacconi, Giovanni Blandino, Paola Nisticò, Anna Bagnato, and Laura RosanòPNAS March 20, 2018 115 (12) 3132-3137; first published February 8, 2018. https://doi.org/10.1073/pnas.1715998115
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- You have accessHigh salt intake causes leptin resistance and obesity in mice by stimulating endogenous fructose production and metabolismMiguel A. Lanaspa, Masanari Kuwabara, Ana Andres-Hernando, Nanxing Li, Christina Cicerchi, Thomas Jensen, David J. Orlicky, Carlos A. Roncal-Jimenez, Takuji Ishimoto, Takahiko Nakagawa, Bernardo Rodriguez-Iturbe, Paul S. MacLean, and Richard J. JohnsonPNAS March 20, 2018 115 (12) 3138-3143; first published March 5, 2018. https://doi.org/10.1073/pnas.1713837115
Microbiology
- Open AccessStructure-based discovery of glycomimetic FmlH ligands as inhibitors of bacterial adhesion during urinary tract infectionVasilios Kalas, Michael E. Hibbing, Amarendar Reddy Maddirala, Ryan Chugani, Jerome S. Pinkner, Laurel K. Mydock-McGrane, Matt S. Conover, James W. Janetka, and Scott J. HultgrenPNAS March 20, 2018 115 (12) E2819-E2828; first published March 5, 2018. https://doi.org/10.1073/pnas.1720140115
- Open AccessMERS coronaviruses from camels in Africa exhibit region-dependent genetic diversityDaniel K. W. Chu, Kenrie P. Y. Hui, Ranawaka A. P. M. Perera, Eve Miguel, Daniela Niemeyer, Jincun Zhao, Rudragouda Channappanavar, Gytis Dudas, Jamiu O. Oladipo, Amadou Traoré, Ouafaa Fassi-Fihri, Abraham Ali, Getnet F. Demissié, Doreen Muth, Michael C. W. Chan, John M. Nicholls, David K. Meyerholz, Sulyman A. Kuranga, Gezahegne Mamo, Ziqi Zhou, Ray T. Y. So, Maged G. Hemida, Richard J. Webby, Francois Roger, Andrew Rambaut, Leo L. M. Poon, Stanley Perlman, Christian Drosten, Veronique Chevalier, and Malik PeirisPNAS March 20, 2018 115 (12) 3144-3149; first published March 5, 2018. https://doi.org/10.1073/pnas.1718769115
- You have accessConserved mechanism of cell-wall synthase regulation revealed by the identification of a new PBP activator in Pseudomonas aeruginosaNeil G. Greene, Coralie Fumeaux, and Thomas G. BernhardtPNAS March 20, 2018 115 (12) 3150-3155; first published March 5, 2018. https://doi.org/10.1073/pnas.1717925115
Neuroscience
- You have accessCommunicating the nutritional value of sugar in DrosophilaFarhan Abu, Justin G. Wang, Yangkyun Oh, Jingjing Deng, Thomas A. Neubert, and Greg S. B. SuhPNAS March 20, 2018 115 (12) E2829-E2838; first published March 5, 2018. https://doi.org/10.1073/pnas.1719827115
- Open AccessBEST1 gene therapy corrects a diffuse retina-wide microdetachment modulated by light exposureKarina E. Guziewicz, Artur V. Cideciyan, William A. Beltran, András M. Komáromy, Valerie L. Dufour, Malgorzata Swider, Simone Iwabe, Alexander Sumaroka, Brian T. Kendrick, Gordon Ruthel, Vince A. Chiodo, Elise Héon, William W. Hauswirth, Samuel G. Jacobson, and Gustavo D. AguirrePNAS March 20, 2018 115 (12) E2839-E2848; first published March 5, 2018. https://doi.org/10.1073/pnas.1720662115
- Open AccessMurine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decayAndrew D. Nguyen, Thi A. Nguyen, Jiasheng Zhang, Swathi Devireddy, Ping Zhou, Anna M. Karydas, Xialian Xu, Bruce L. Miller, Frank Rigo, Shawn M. Ferguson, Eric J. Huang, Tobias C. Walther, and Robert V. Farese Jr.PNAS March 20, 2018 115 (12) E2849-E2858; first published March 6, 2018. https://doi.org/10.1073/pnas.1722344115
- Open AccesshnRNP R and its main interactor, the noncoding RNA 7SK, coregulate the axonal transcriptome of motoneuronsMichael Briese, Lena Saal-Bauernschubert, Changhe Ji, Mehri Moradi, Hanaa Ghanawi, Michael Uhl, Silke Appenzeller, Rolf Backofen, and Michael SendtnerPNAS March 20, 2018 115 (12) E2859-E2868; first published March 5, 2018. https://doi.org/10.1073/pnas.1721670115
- You have accessDynamic patterns of cortical expansion during folding of the preterm human brainKara E. Garcia, Emma C. Robinson, Dimitrios Alexopoulos, Donna L. Dierker, Matthew F. Glasser, Timothy S. Coalson, Cynthia M. Ortinau, Daniel Rueckert, Larry A. Taber, David C. Van Essen, Cynthia E. Rogers, Christopher D. Smyser, and Philip V. BaylyPNAS March 20, 2018 115 (12) 3156-3161; first published March 5, 2018. https://doi.org/10.1073/pnas.1715451115
- You have accessSusceptibility of brain atrophy to TRIB3 in Alzheimer’s disease, evidence from functional prioritization in imaging geneticsMarco Lorenzi, Andre Altmann, Boris Gutman, Selina Wray, Charles Arber, Derrek P. Hibar, Neda Jahanshad, Jonathan M. Schott, Daniel C. Alexander, Paul M. Thompson, Sebastien Ourselin, and for the Alzheimer’s Disease Neuroimaging InitiativePNAS March 20, 2018 115 (12) 3162-3167; first published March 6, 2018. https://doi.org/10.1073/pnas.1706100115
- Open AccessRare variants in axonogenesis genes connect three families with sound–color synesthesiaAmanda K. Tilot, Katerina S. Kucera, Arianna Vino, Julian E. Asher, Simon Baron-Cohen, and Simon E. FisherPNAS March 20, 2018 115 (12) 3168-3173; first published March 5, 2018. https://doi.org/10.1073/pnas.1715492115
Physiology
- You have accessPhysical and geometric constraints shape the labyrinth-like nasal cavityDavid Zwicker, Rodolfo Ostilla-Mónico, Daniel E. Lieberman, and Michael P. BrennerPNAS March 20, 2018 115 (12) 2936-2941; first published March 5, 2018. https://doi.org/10.1073/pnas.1714795115
Plant Biology
- You have accessSimultaneous imaging and functional studies reveal a tight correlation between calcium and actin networksCarlisle S. Bascom Jr., Lawrence J. Winship, and Magdalena BezanillaPNAS March 20, 2018 115 (12) E2869-E2878; first published March 5, 2018. https://doi.org/10.1073/pnas.1711037115
- Open AccessLoss of function of a rice TPR-domain RNA-binding protein confers broad-spectrum disease resistance
- From the Cover
Xiaogang Zhou, Haicheng Liao, Mawsheng Chern, Junjie Yin, Yufei Chen, Jianping Wang, Xiaobo Zhu, Zhixiong Chen, Can Yuan, Wen Zhao, Jing Wang, Weitao Li, Min He, Bingtian Ma, Jichun Wang, Peng Qin, Weilan Chen, Yuping Wang, Jiali Liu, Yangwen Qian, Wenming Wang, Xianjun Wu, Ping Li, Lihuang Zhu, Shigui Li, Pamela C. Ronald, and Xuewei ChenPNAS March 20, 2018 115 (12) 3174-3179; first published February 5, 2018. https://doi.org/10.1073/pnas.1705927115See companion article:
- Open AccessSolution of the multistep pathway for assembly of corynanthean, strychnos, iboga, and aspidosperma monoterpenoid indole alkaloids from 19E-geissoschizineYang Qu, Michael E. A. M. Easson, Razvan Simionescu, Josef Hajicek, Antje M. K. Thamm, Vonny Salim, and Vincenzo De LucaPNAS March 20, 2018 115 (12) 3180-3185; first published March 6, 2018. https://doi.org/10.1073/pnas.1719979115
Psychological and Cognitive Sciences
- Open AccessIntegration of speed and time for estimating time to contactChia-Jung Chang and Mehrdad JazayeriPNAS March 20, 2018 115 (12) E2879-E2887; first published March 5, 2018. https://doi.org/10.1073/pnas.1713316115
- You have accessHow cognitive and reactive fear circuits optimize escape decisions in humansSong Qi, Demis Hassabis, Jiayin Sun, Fangjian Guo, Nathaniel Daw, and Dean MobbsPNAS March 20, 2018 115 (12) 3186-3191; first published March 5, 2018. https://doi.org/10.1073/pnas.1712314115
Sustainability Science
- Open AccessCitywide cluster randomized trial to restore blighted vacant land and its effects on violence, crime, and fearCharles C. Branas, Eugenia South, Michelle C. Kondo, Bernadette C. Hohl, Philippe Bourgois, Douglas J. Wiebe, and John M. MacDonaldPNAS March 20, 2018 115 (12) 2946-2951; first published February 26, 2018. https://doi.org/10.1073/pnas.1718503115
Systems Biology
- You have accessNongenetic origins of cell-to-cell variability in B lymphocyte proliferationSimon Mitchell, Koushik Roy, Thomas A. Zangle, and Alexander HoffmannPNAS March 20, 2018 115 (12) E2888-E2897; first published March 7, 2018. https://doi.org/10.1073/pnas.1715639115
Corrections (Online Only)
- You have accessCorrection for Lange et al., A mitochondrial ferredoxin is essential for biogenesis of cellular iron-sulfur proteinsPNAS March 20, 2018 115 (12) E2898; first published March 12, 2018. https://doi.org/10.1073/pnas.1803134115
- You have accessCorrection for Kudalkar et al., From in silico hit to long-acting late-stage preclinical candidate to combat HIV-1 infectionPNAS March 20, 2018 115 (12) E2899; first published March 12, 2018. https://doi.org/10.1073/pnas.1803199115
Retractions (Online Only)
- You have accessRetraction for Skau et al., Inverted formin 2 in focal adhesions promotes dorsal stress fiber and fibrillar adhesion formation to drive extracellular matrix assemblyPNAS March 20, 2018 115 (12) E2900; first published March 12, 2018. https://doi.org/10.1073/pnas.1803125115
- You have accessRetraction for Maisonneuve et al., Bacterial persistence by RNA endonucleasesPNAS March 20, 2018 115 (12) E2901; first published March 12, 2018. https://doi.org/10.1073/pnas.1803278115
Commentaries
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