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About the Cover

April 17, 2018; vol. 115 no. 16

This Week in PNAS

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    In This Issue
    PNAS April 17, 2018 115 (16) 3985-3987; https://doi.org/10.1073/iti1618115

Letters (Online Only)

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    Genetic variation in VAC14 is associated with bacteremia secondary to diverse pathogens in African children
    James J. Gilchrist, Alexander J. Mentzer, Anna Rautanen, Matti Pirinen, Salim Mwarumba, Patricia Njuguna, Neema Mturi, Wellcome Trust Case-Control Consortium 2, The Kenyan Bacteraemia Study Group, Thomas N. Williams, J. Anthony G. Scott, and Adrian V. S. Hill
    PNAS April 17, 2018 115 (16) E3601-E3603; published ahead of print March 27, 2018. https://doi.org/10.1073/pnas.1802071115
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    Reply to Gilchrist et al.: Possible roles for VAC14 in multiple infectious diseases
    Monica I. Alvarez and Dennis C. Ko
    PNAS April 17, 2018 115 (16) E3604-E3605; published ahead of print March 27, 2018. https://doi.org/10.1073/pnas.1803533115
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    Does selecting ligand shape γδ-TCR repertoire?
    Yueh-hsiu Chien
    PNAS April 17, 2018 115 (16) E3606; published ahead of print April 3, 2018. https://doi.org/10.1073/pnas.1804001115
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    Reply to Chien: Clarification of the effect of ligand on γδ-TCR repertoire selection
    Shawn P. Fahl and David L. Wiest
    PNAS April 17, 2018 115 (16) E3607-E3608; published ahead of print April 3, 2018. https://doi.org/10.1073/pnas.1804193115

News Feature

An in-depth look at trending science issues.
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    News Feature: The quest to solve sepsis
    • Front Matter
    Carrie Arnold
    PNAS April 17, 2018 115 (16) 3988-3991; https://doi.org/10.1073/pnas.1803551115

Commentaries

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    The labyrinth of human variation
    Erik Trinkaus
    PNAS April 17, 2018 115 (16) 3992-3994; published ahead of print April 4, 2018. https://doi.org/10.1073/pnas.1804794115
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    Physiological constraints on marine mammal body size
    J. A. Goldbogen
    PNAS April 17, 2018 115 (16) 3995-3997; published ahead of print April 4, 2018. https://doi.org/10.1073/pnas.1804077115
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    Auditory motion parallax
    William A. Yost
    PNAS April 17, 2018 115 (16) 3998-4000; published ahead of print April 5, 2018. https://doi.org/10.1073/pnas.1803547115

PNAS Plus Significance Statements

Brief statements written by the authors about the significance of their papers.
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    PNAS Plus Significance Statements
    PNAS April 17, 2018 115 (16) 4001-4005; https://doi.org/10.1073/pnas.ss11516

Perspective

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    Processes and patterns of interaction as units of selection: An introduction to ITSNTS thinking
    W. Ford Doolittle and S. Andrew Inkpen
    PNAS April 17, 2018 115 (16) 4006-4014; published ahead of print March 26, 2018. https://doi.org/10.1073/pnas.1722232115

Climate Change, Policy, and Carbon Sequestration in China Special Feature (Free Online)

  • Introduction

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      Climate change, human impacts, and carbon sequestration in China
      • From the Cover
      Jingyun Fang, Guirui Yu, Lingli Liu, Shuijin Hu, and F. Stuart Chapin III
      PNAS April 17, 2018 115 (16) 4015-4020; published ahead of print April 17, 2018. https://doi.org/10.1073/pnas.1700304115
  • Research Articles

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      Carbon pools in China’s terrestrial ecosystems: New estimates based on an intensive field survey
      Xuli Tang, Xia Zhao, Yongfei Bai, Zhiyao Tang, Wantong Wang, Yongcun Zhao, Hongwei Wan, Zongqiang Xie, Xuezheng Shi, Bingfang Wu, Gengxu Wang, Junhua Yan, Keping Ma, Sheng Du, Shenggong Li, Shijie Han, Youxin Ma, Huifeng Hu, Nianpeng He, Yuanhe Yang, Wenxuan Han, Hongling He, Guirui Yu, Jingyun Fang, and Guoyi Zhou
      PNAS April 17, 2018 115 (16) 4021-4026; https://doi.org/10.1073/pnas.1700291115
    • You have access
      Plant diversity enhances productivity and soil carbon storage
      Shiping Chen, Wantong Wang, Wenting Xu, Yang Wang, Hongwei Wan, Dima Chen, Zhiyao Tang, Xuli Tang, Guoyi Zhou, Zongqiang Xie, Daowei Zhou, Zhouping Shangguan, Jianhui Huang, Jin-Sheng He, Yanfen Wang, Jiandong Sheng, Lisong Tang, Xinrong Li, Ming Dong, Yan Wu, Qiufeng Wang, Zhiheng Wang, Jianguo Wu, F. Stuart Chapin III, and Yongfei Bai
      PNAS April 17, 2018 115 (16) 4027-4032; https://doi.org/10.1073/pnas.1700298114
    • You have access
      Patterns of plant carbon, nitrogen, and phosphorus concentration in relation to productivity in China’s terrestrial ecosystems
      Zhiyao Tang, Wenting Xu, Guoyi Zhou, Yongfei Bai, Jiaxiang Li, Xuli Tang, Dima Chen, Qing Liu, Wenhong Ma, Gaoming Xiong, Honglin He, Nianpeng He, Yanpei Guo, Qiang Guo, Jiangling Zhu, Wenxuan Han, Huifeng Hu, Jingyun Fang, and Zongqiang Xie
      PNAS April 17, 2018 115 (16) 4033-4038; published ahead of print April 16, 2018. https://doi.org/10.1073/pnas.1700295114
    • You have access
      Effects of national ecological restoration projects on carbon sequestration in China from 2001 to 2010
      Fei Lu, Huifeng Hu, Wenjuan Sun, Jiaojun Zhu, Guobin Liu, Wangming Zhou, Quanfa Zhang, Peili Shi, Xiuping Liu, Xing Wu, Lu Zhang, Xiaohua Wei, Limin Dai, Kerong Zhang, Yirong Sun, Sha Xue, Wanjun Zhang, Dingpeng Xiong, Lei Deng, Bojie Liu, Li Zhou, Chao Zhang, Xiao Zheng, Jiansheng Cao, Yao Huang, Nianpeng He, Guoyi Zhou, Yongfei Bai, Zongqiang Xie, Zhiyao Tang, Bingfang Wu, Jingyun Fang, Guohua Liu, and Guirui Yu
      PNAS April 17, 2018 115 (16) 4039-4044; https://doi.org/10.1073/pnas.1700294115
    • You have access
      Economics- and policy-driven organic carbon input enhancement dominates soil organic carbon accumulation in Chinese croplands
      Yongcun Zhao, Meiyan Wang, Shuijin Hu, Xudong Zhang, Zhu Ouyang, Ganlin Zhang, Biao Huang, Shiwei Zhao, Jinshui Wu, Deti Xie, Bo Zhu, Dongsheng Yu, Xianzhang Pan, Shengxiang Xu, and Xuezheng Shi
      PNAS April 17, 2018 115 (16) 4045-4050; https://doi.org/10.1073/pnas.1700292114
    • You have access
      Shifting plant species composition in response to climate change stabilizes grassland primary production
      Huiying Liu, Zhaorong Mi, Li Lin, Yonghui Wang, Zhenhua Zhang, Fawei Zhang, Hao Wang, Lingli Liu, Biao Zhu, Guangmin Cao, Xinquan Zhao, Nathan J. Sanders, Aimée T. Classen, Peter B. Reich, and Jin-Sheng He
      PNAS April 17, 2018 115 (16) 4051-4056; https://doi.org/10.1073/pnas.1700299114

Physical Sciences

  • Applied Mathematics

    • Open Access
      Multiscale mixing patterns in networks
      Leto Peel, Jean-Charles Delvenne, and Renaud Lambiotte
      PNAS April 17, 2018 115 (16) 4057-4062; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1713019115
  • Applied Physical Sciences

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      Thermodynamic limits of energy harvesting from outgoing thermal radiation
      Siddharth Buddhiraju, Parthiban Santhanam, and Shanhui Fan
      PNAS April 17, 2018 115 (16) E3609-E3615; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1717595115
    • You have access
      Dramatic pressure-sensitive ion conduction in conical nanopores
      Laetitia Jubin, Anthony Poggioli, Alessandro Siria, and Lydéric Bocquet
      PNAS April 17, 2018 115 (16) 4063-4068; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1721987115
  • Biophysics and Computational Biology

    • You have access
      Roll maneuvers are essential for active reorientation of Caenorhabditis elegans in 3D media
      Alejandro Bilbao, Amar K. Patel, Mizanur Rahman, Siva A. Vanapalli, and Jerzy Blawzdziewicz
      PNAS April 17, 2018 115 (16) E3616-E3625; published ahead of print April 4, 2018. https://doi.org/10.1073/pnas.1706754115
    • Open Access
      Accurate and sensitive quantification of protein-DNA binding affinity
      Chaitanya Rastogi, H. Tomas Rube, Judith F. Kribelbauer, Justin Crocker, Ryan E. Loker, Gabriella D. Martini, Oleg Laptenko, William A. Freed-Pastor, Carol Prives, David L. Stern, Richard S. Mann, and Harmen J. Bussemaker
      PNAS April 17, 2018 115 (16) E3692-E3701; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1714376115
    • Open Access
      Comprehensive, high-resolution binding energy landscapes reveal context dependencies of transcription factor binding
      Daniel D. Le, Tyler C. Shimko, Arjun K. Aditham, Allison M. Keys, Scott A. Longwell, Yaron Orenstein, and Polly M. Fordyce
      PNAS April 17, 2018 115 (16) E3702-E3711; published ahead of print March 27, 2018. https://doi.org/10.1073/pnas.1715888115
    • You have access
      Robust, linear correlations between growth rates and β-lactam–mediated lysis rates
      Anna J. Lee, Shangying Wang, Hannah R. Meredith, Bihan Zhuang, Zhuojun Dai, and Lingchong You
      PNAS April 17, 2018 115 (16) 4069-4074; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1719504115
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      Cell contraction induces long-ranged stress stiffening in the extracellular matrix
      Yu Long Han, Pierre Ronceray, Guoqiang Xu, Andrea Malandrino, Roger D. Kamm, Martin Lenz, Chase P. Broedersz, and Ming Guo
      PNAS April 17, 2018 115 (16) 4075-4080; published ahead of print April 4, 2018. https://doi.org/10.1073/pnas.1722619115
    • Open Access
      Structural dynamics is a determinant of the functional significance of missense variants
      Luca Ponzoni and Ivet Bahar
      PNAS April 17, 2018 115 (16) 4164-4169; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1715896115
  • Chemistry

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      Molecular excitonic seesaws
      Philipp Wilhelm, Jakob Schedlbauer, Florian Hinderer, Daniel Hennen, Sigurd Höger, Jan Vogelsang, and John M. Lupton
      PNAS April 17, 2018 115 (16) E3626-E3634; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1722229115
    • Open Access
      Label-free and charge-sensitive dynamic imaging of lipid membrane hydration on millisecond time scales
      Orly B. Tarun, Christof Hannesschläger, Peter Pohl, and Sylvie Roke
      PNAS April 17, 2018 115 (16) 4081-4086; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1719347115
    • Open Access
      Direct electrochemical observation of glucosidase activity in isolated single lysosomes from a living cell
      Rongrong Pan, Mingchen Xu, James D. Burgess, Dechen Jiang, and Hong-Yuan Chen
      PNAS April 17, 2018 115 (16) 4087-4092; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1719844115
    • You have access
      Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk
      Ioanna Ntai, Luca Fornelli, Caroline J. DeHart, Josiah E. Hutton, Peter F. Doubleday, Richard D. LeDuc, Alexandra J. van Nispen, Ryan T. Fellers, Gordon Whiteley, Emily S. Boja, Henry Rodriguez, and Neil L. Kelleher
      PNAS April 17, 2018 115 (16) 4140-4145; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1716122115
  • Computer Sciences

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      Word embeddings quantify 100 years of gender and ethnic stereotypes
      Nikhil Garg, Londa Schiebinger, Dan Jurafsky, and James Zou
      PNAS April 17, 2018 115 (16) E3635-E3644; published ahead of print April 3, 2018. https://doi.org/10.1073/pnas.1720347115
    • You have access
      Characterizing the human hippocampus in aging and Alzheimer’s disease using a computational atlas derived from ex vivo MRI and histology
      Daniel H. Adler, Laura E. M. Wisse, Ranjit Ittyerah, John B. Pluta, Song-Lin Ding, Long Xie, Jiancong Wang, Salmon Kadivar, John L. Robinson, Theresa Schuck, John Q. Trojanowski, Murray Grossman, John A. Detre, Mark A. Elliott, Jon B. Toledo, Weixia Liu, Stephen Pickup, Michael I. Miller, Sandhitsu R. Das, David A. Wolk, and Paul A. Yushkevich
      PNAS April 17, 2018 115 (16) 4252-4257; published ahead of print March 28, 2018. https://doi.org/10.1073/pnas.1801093115
  • Earth, Atmospheric, and Planetary Sciences

    • Open Access
      Critical impact of vegetation physiology on the continental hydrologic cycle in response to increasing CO2
      Léo Lemordant, Pierre Gentine, Abigail S. Swann, Benjamin I. Cook, and Jacob Scheff
      PNAS April 17, 2018 115 (16) 4093-4098; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1720712115
    • You have access
      Effects of iron on the lattice thermal conductivity of Earth’s deep mantle and implications for mantle dynamics
      Wen-Pin Hsieh, Frédéric Deschamps, Takuo Okuchi, and Jung-Fu Lin
      PNAS April 17, 2018 115 (16) 4099-4104; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1718557115
    • Open Access
      Constraining the climate and ocean pH of the early Earth with a geological carbon cycle model
      Joshua Krissansen-Totton, Giada N. Arney, and David C. Catling
      PNAS April 17, 2018 115 (16) 4105-4110; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1721296115
    • You have access
      Energetic tradeoffs control the size distribution of aquatic mammals
      • From the Cover
      William Gearty, Craig R. McClain, and Jonathan L. Payne
      PNAS April 17, 2018 115 (16) 4194-4199; published ahead of print March 26, 2018. https://doi.org/10.1073/pnas.1712629115
  • Physics

    • Open Access
      Fluctuations uncover a distinct class of traveling waves
      Gabriel Birzu, Oskar Hallatschek, and Kirill S. Korolev
      PNAS April 17, 2018 115 (16) E3645-E3654; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1715737115
    • You have access
      Soft self-assembly of Weyl materials for light and sound
      Michel Fruchart, Seung-Yeol Jeon, Kahyun Hur, Vadim Cheianov, Ulrich Wiesner, and Vincenzo Vitelli
      PNAS April 17, 2018 115 (16) E3655-E3664; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1720828115
    • You have access
      Topological order in the pseudogap metal
      Mathias S. Scheurer, Shubhayu Chatterjee, Wei Wu, Michel Ferrero, Antoine Georges, and Subir Sachdev
      PNAS April 17, 2018 115 (16) E3665-E3672; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1720580115
    • Open Access
      Mechanosensitivity of Jagged–Notch signaling can induce a switch-type behavior in vascular homeostasis
      Sandra Loerakker, Oscar M. J. A. Stassen, Fleur M. ter Huurne, Marcelo Boareto, Carlijn V. C. Bouten, and Cecilia M. Sahlgren
      PNAS April 17, 2018 115 (16) E3682-E3691; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1715277115
  • Sustainability Science

    • You have access
      Carbon pools in China’s terrestrial ecosystems: New estimates based on an intensive field survey
      Xuli Tang, Xia Zhao, Yongfei Bai, Zhiyao Tang, Wantong Wang, Yongcun Zhao, Hongwei Wan, Zongqiang Xie, Xuezheng Shi, Bingfang Wu, Gengxu Wang, Junhua Yan, Keping Ma, Sheng Du, Shenggong Li, Shijie Han, Youxin Ma, Huifeng Hu, Nianpeng He, Yuanhe Yang, Wenxuan Han, Hongling He, Guirui Yu, Jingyun Fang, and Guoyi Zhou
      PNAS April 17, 2018 115 (16) 4021-4026; https://doi.org/10.1073/pnas.1700291115
    • You have access
      Patterns of plant carbon, nitrogen, and phosphorus concentration in relation to productivity in China’s terrestrial ecosystems
      Zhiyao Tang, Wenting Xu, Guoyi Zhou, Yongfei Bai, Jiaxiang Li, Xuli Tang, Dima Chen, Qing Liu, Wenhong Ma, Gaoming Xiong, Honglin He, Nianpeng He, Yanpei Guo, Qiang Guo, Jiangling Zhu, Wenxuan Han, Huifeng Hu, Jingyun Fang, and Zongqiang Xie
      PNAS April 17, 2018 115 (16) 4033-4038; published ahead of print April 16, 2018. https://doi.org/10.1073/pnas.1700295114
    • You have access
      Shifting plant species composition in response to climate change stabilizes grassland primary production
      Huiying Liu, Zhaorong Mi, Li Lin, Yonghui Wang, Zhenhua Zhang, Fawei Zhang, Hao Wang, Lingli Liu, Biao Zhu, Guangmin Cao, Xinquan Zhao, Nathan J. Sanders, Aimée T. Classen, Peter B. Reich, and Jin-Sheng He
      PNAS April 17, 2018 115 (16) 4051-4056; https://doi.org/10.1073/pnas.1700299114
    • Open Access
      China, the United States, and competition for resources that enable emerging technologies
      Andrew L. Gulley, Nedal T. Nassar, and Sean Xun
      PNAS April 17, 2018 115 (16) 4111-4115; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1717152115

Social Sciences

  • Anthropology

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      Origins and spread of fluted-point technology in the Canadian Ice-Free Corridor and eastern Beringia
      Heather L. Smith and Ted Goebel
      PNAS April 17, 2018 115 (16) 4116-4121; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1800312115
  • Psychological and Cognitive Sciences

    • Open Access
      The computational form of craving is a selective multiplication of economic value
      Anna B. Konova, Kenway Louie, and Paul W. Glimcher
      PNAS April 17, 2018 115 (16) 4122-4127; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1714443115
  • Social Sciences

    • You have access
      Word embeddings quantify 100 years of gender and ethnic stereotypes
      Nikhil Garg, Londa Schiebinger, Dan Jurafsky, and James Zou
      PNAS April 17, 2018 115 (16) E3635-E3644; published ahead of print April 3, 2018. https://doi.org/10.1073/pnas.1720347115
  • Sustainability Science

    • Open Access
      China, the United States, and competition for resources that enable emerging technologies
      Andrew L. Gulley, Nedal T. Nassar, and Sean Xun
      PNAS April 17, 2018 115 (16) 4111-4115; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1717152115

Biological Sciences

  • Anthropology

    • Open Access
      Human bony labyrinth is an indicator of population history and dispersal from Africa
      • From the Cover
      Marcia S. Ponce de León, Toetik Koesbardiati, John David Weissmann, Marco Milella, Carlos S. Reyna-Blanco, Gen Suwa, Osamu Kondo, Anna-Sapfo Malaspinas, Tim D. White, and Christoph P. E. Zollikofer
      PNAS April 17, 2018 115 (16) 4128-4133; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1717873115
    • Open Access
      Hip extensor mechanics and the evolution of walking and climbing capabilities in humans, apes, and fossil hominins
      Elaine E. Kozma, Nicole M. Webb, William E. H. Harcourt-Smith, David A. Raichlen, Kristiaan D'Août, Mary H. Brown, Emma M. Finestone, Stephen R. Ross, Peter Aerts, and Herman Pontzer
      PNAS April 17, 2018 115 (16) 4134-4139; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1715120115
  • Biochemistry

    • You have access
      Pharmacological activation of estrogen receptor beta augments innate immunity to suppress cancer metastasis
      Linjie Zhao, Shuang Huang, Shenglin Mei, Zhengnan Yang, Lian Xu, Nianxin Zhou, Qilian Yang, Qiuhong Shen, Wei Wang, Xiaobing Le, Wayne Bond Lau, Bonnie Lau, Xin Wang, Tao Yi, Xia Zhao, Yuquan Wei, Margaret Warner, Jan-Åke Gustafsson, and Shengtao Zhou
      PNAS April 17, 2018 115 (16) E3673-E3681; published ahead of print March 28, 2018. https://doi.org/10.1073/pnas.1803291115
    • You have access
      Precise characterization of KRAS4b proteoforms in human colorectal cells and tumors reveals mutation/modification cross-talk
      Ioanna Ntai, Luca Fornelli, Caroline J. DeHart, Josiah E. Hutton, Peter F. Doubleday, Richard D. LeDuc, Alexandra J. van Nispen, Ryan T. Fellers, Gordon Whiteley, Emily S. Boja, Henry Rodriguez, and Neil L. Kelleher
      PNAS April 17, 2018 115 (16) 4140-4145; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1716122115
    • You have access
      Oversized galactosides as a probe for conformational dynamics in LacY
      Irina Smirnova, Vladimir Kasho, Xiaoxu Jiang, Hong-Ming Chen, Stephen G. Withers, and H. Ronald Kaback
      PNAS April 17, 2018 115 (16) 4146-4151; published ahead of print March 30, 2018. https://doi.org/10.1073/pnas.1800706115
    • You have access
      Observation of acetyl phosphate formation in mammalian mitochondria using real-time in-organelle NMR metabolomics
      Wen Jun Xu, He Wen, Han Sun Kim, Yoon-Joo Ko, Seung-Mo Dong, In-Sun Park, Jong In Yook, and Sunghyouk Park
      PNAS April 17, 2018 115 (16) 4152-4157; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1720908115
    • Open Access
      Molecular structural diversity of mitochondrial cardiolipins
      Gregor Oemer, Katharina Lackner, Katharina Muigg, Gerhard Krumschnabel, Katrin Watschinger, Sabrina Sailer, Herbert Lindner, Erich Gnaiger, Saskia B. Wortmann, Ernst R. Werner, Johannes Zschocke, and Markus A. Keller
      PNAS April 17, 2018 115 (16) 4158-4163; published ahead of print April 4, 2018. https://doi.org/10.1073/pnas.1719407115
  • Biophysics and Computational Biology

    • You have access
      Roll maneuvers are essential for active reorientation of Caenorhabditis elegans in 3D media
      Alejandro Bilbao, Amar K. Patel, Mizanur Rahman, Siva A. Vanapalli, and Jerzy Blawzdziewicz
      PNAS April 17, 2018 115 (16) E3616-E3625; published ahead of print April 4, 2018. https://doi.org/10.1073/pnas.1706754115
    • Open Access
      Mechanosensitivity of Jagged–Notch signaling can induce a switch-type behavior in vascular homeostasis
      Sandra Loerakker, Oscar M. J. A. Stassen, Fleur M. ter Huurne, Marcelo Boareto, Carlijn V. C. Bouten, and Cecilia M. Sahlgren
      PNAS April 17, 2018 115 (16) E3682-E3691; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1715277115
    • Open Access
      Accurate and sensitive quantification of protein-DNA binding affinity
      Chaitanya Rastogi, H. Tomas Rube, Judith F. Kribelbauer, Justin Crocker, Ryan E. Loker, Gabriella D. Martini, Oleg Laptenko, William A. Freed-Pastor, Carol Prives, David L. Stern, Richard S. Mann, and Harmen J. Bussemaker
      PNAS April 17, 2018 115 (16) E3692-E3701; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1714376115
    • Open Access
      Comprehensive, high-resolution binding energy landscapes reveal context dependencies of transcription factor binding
      Daniel D. Le, Tyler C. Shimko, Arjun K. Aditham, Allison M. Keys, Scott A. Longwell, Yaron Orenstein, and Polly M. Fordyce
      PNAS April 17, 2018 115 (16) E3702-E3711; published ahead of print March 27, 2018. https://doi.org/10.1073/pnas.1715888115
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      Spatial organization and dynamics of RNase E and ribosomes in Caulobacter crescentus
      Camille A. Bayas, Jiarui Wang, Marissa K. Lee, Jared M. Schrader, Lucy Shapiro, and W. E. Moerner
      PNAS April 17, 2018 115 (16) E3712-E3721; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1721648115
    • You have access
      Cell contraction induces long-ranged stress stiffening in the extracellular matrix
      Yu Long Han, Pierre Ronceray, Guoqiang Xu, Andrea Malandrino, Roger D. Kamm, Martin Lenz, Chase P. Broedersz, and Ming Guo
      PNAS April 17, 2018 115 (16) 4075-4080; published ahead of print April 4, 2018. https://doi.org/10.1073/pnas.1722619115
    • Open Access
      Label-free and charge-sensitive dynamic imaging of lipid membrane hydration on millisecond time scales
      Orly B. Tarun, Christof Hannesschläger, Peter Pohl, and Sylvie Roke
      PNAS April 17, 2018 115 (16) 4081-4086; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1719347115
    • Open Access
      Structural dynamics is a determinant of the functional significance of missense variants
      Luca Ponzoni and Ivet Bahar
      PNAS April 17, 2018 115 (16) 4164-4169; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1715896115
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      Microbes vs. chemistry in the origin of the anaerobic gut lumen
      Elliot S. Friedman, Kyle Bittinger, Tatiana V. Esipova, Likai Hou, Lillian Chau, Jack Jiang, Clementina Mesaros, Peder J. Lund, Xue Liang, Garret A. FitzGerald, Mark Goulian, Daeyeon Lee, Benjamin A. Garcia, Ian A. Blair, Sergei A. Vinogradov, and Gary D. Wu
      PNAS April 17, 2018 115 (16) 4170-4175; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1718635115
  • Cell Biology

    • Open Access
      Insight from the maximal activation of the signal transduction excitable network in Dictyostelium discoideum
      Marc Edwards, Huaqing Cai, Bedri Abubaker-Sharif, Yu Long, Thomas J. Lampert, and Peter N. Devreotes
      PNAS April 17, 2018 115 (16) E3722-E3730; published ahead of print March 30, 2018. https://doi.org/10.1073/pnas.1710480115
    • Open Access
      Direct electrochemical observation of glucosidase activity in isolated single lysosomes from a living cell
      Rongrong Pan, Mingchen Xu, James D. Burgess, Dechen Jiang, and Hong-Yuan Chen
      PNAS April 17, 2018 115 (16) 4087-4092; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1719844115
    • Open Access
      Increased autophagy blocks HER2-mediated breast tumorigenesis
      Silvia Vega-Rubín-de-Celis, Zhongju Zou, Álvaro F. Fernández, Bo Ci, Min Kim, Guanghua Xiao, Yang Xie, and Beth Levine
      PNAS April 17, 2018 115 (16) 4176-4181; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1717800115
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      TWEAK and RIPK1 mediate a second wave of cell death during AKI
      Diego Martin-Sanchez, Miguel Fontecha-Barriuso, Susana Carrasco, Maria Dolores Sanchez-Niño, Anne von Mässenhausen, Andreas Linkermann, Pablo Cannata-Ortiz, Marta Ruiz-Ortega, Jesus Egido, Alberto Ortiz, and Ana Belen Sanz
      PNAS April 17, 2018 115 (16) 4182-4187; published ahead of print March 27, 2018. https://doi.org/10.1073/pnas.1716578115
  • Developmental Biology

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      Evolutionary emergence of the rac3b/rfng/sgca regulatory cluster refined mechanisms for hindbrain boundaries formation
      Joaquín Letelier, Javier Terriente, Ivan Belzunce, Adria Voltes, Cristian Alberto Undurraga, Rocio Polvillo, Lucie Devos, Juan J. Tena, Ignacio Maeso, Sylvie Retaux, José Luis Gomez-Skarmeta, Juan R. Martínez-Morales, and Cristina Pujades
      PNAS April 17, 2018 115 (16) E3731-E3740; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1719885115
    • Open Access
      Transient fibrosis resolves via fibroblast inactivation in the regenerating zebrafish heart
      Héctor Sánchez-Iranzo, María Galardi-Castilla, Andrés Sanz-Morejón, Juan Manuel González-Rosa, Ricardo Costa, Alexander Ernst, Julio Sainz de Aja, Xavier Langa, and Nadia Mercader
      PNAS April 17, 2018 115 (16) 4188-4193; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1716713115
  • Ecology

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      Carbon pools in China’s terrestrial ecosystems: New estimates based on an intensive field survey
      Xuli Tang, Xia Zhao, Yongfei Bai, Zhiyao Tang, Wantong Wang, Yongcun Zhao, Hongwei Wan, Zongqiang Xie, Xuezheng Shi, Bingfang Wu, Gengxu Wang, Junhua Yan, Keping Ma, Sheng Du, Shenggong Li, Shijie Han, Youxin Ma, Huifeng Hu, Nianpeng He, Yuanhe Yang, Wenxuan Han, Hongling He, Guirui Yu, Jingyun Fang, and Guoyi Zhou
      PNAS April 17, 2018 115 (16) 4021-4026; https://doi.org/10.1073/pnas.1700291115
    • You have access
      Plant diversity enhances productivity and soil carbon storage
      Shiping Chen, Wantong Wang, Wenting Xu, Yang Wang, Hongwei Wan, Dima Chen, Zhiyao Tang, Xuli Tang, Guoyi Zhou, Zongqiang Xie, Daowei Zhou, Zhouping Shangguan, Jianhui Huang, Jin-Sheng He, Yanfen Wang, Jiandong Sheng, Lisong Tang, Xinrong Li, Ming Dong, Yan Wu, Qiufeng Wang, Zhiheng Wang, Jianguo Wu, F. Stuart Chapin III, and Yongfei Bai
      PNAS April 17, 2018 115 (16) 4027-4032; https://doi.org/10.1073/pnas.1700298114
    • You have access
      Patterns of plant carbon, nitrogen, and phosphorus concentration in relation to productivity in China’s terrestrial ecosystems
      Zhiyao Tang, Wenting Xu, Guoyi Zhou, Yongfei Bai, Jiaxiang Li, Xuli Tang, Dima Chen, Qing Liu, Wenhong Ma, Gaoming Xiong, Honglin He, Nianpeng He, Yanpei Guo, Qiang Guo, Jiangling Zhu, Wenxuan Han, Huifeng Hu, Jingyun Fang, and Zongqiang Xie
      PNAS April 17, 2018 115 (16) 4033-4038; published ahead of print April 16, 2018. https://doi.org/10.1073/pnas.1700295114
    • You have access
      Effects of national ecological restoration projects on carbon sequestration in China from 2001 to 2010
      Fei Lu, Huifeng Hu, Wenjuan Sun, Jiaojun Zhu, Guobin Liu, Wangming Zhou, Quanfa Zhang, Peili Shi, Xiuping Liu, Xing Wu, Lu Zhang, Xiaohua Wei, Limin Dai, Kerong Zhang, Yirong Sun, Sha Xue, Wanjun Zhang, Dingpeng Xiong, Lei Deng, Bojie Liu, Li Zhou, Chao Zhang, Xiao Zheng, Jiansheng Cao, Yao Huang, Nianpeng He, Guoyi Zhou, Yongfei Bai, Zongqiang Xie, Zhiyao Tang, Bingfang Wu, Jingyun Fang, Guohua Liu, and Guirui Yu
      PNAS April 17, 2018 115 (16) 4039-4044; https://doi.org/10.1073/pnas.1700294115
    • You have access
      Economics- and policy-driven organic carbon input enhancement dominates soil organic carbon accumulation in Chinese croplands
      Yongcun Zhao, Meiyan Wang, Shuijin Hu, Xudong Zhang, Zhu Ouyang, Ganlin Zhang, Biao Huang, Shiwei Zhao, Jinshui Wu, Deti Xie, Bo Zhu, Dongsheng Yu, Xianzhang Pan, Shengxiang Xu, and Xuezheng Shi
      PNAS April 17, 2018 115 (16) 4045-4050; https://doi.org/10.1073/pnas.1700292114
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      Shifting plant species composition in response to climate change stabilizes grassland primary production
      Huiying Liu, Zhaorong Mi, Li Lin, Yonghui Wang, Zhenhua Zhang, Fawei Zhang, Hao Wang, Lingli Liu, Biao Zhu, Guangmin Cao, Xinquan Zhao, Nathan J. Sanders, Aimée T. Classen, Peter B. Reich, and Jin-Sheng He
      PNAS April 17, 2018 115 (16) 4051-4056; https://doi.org/10.1073/pnas.1700299114
  • Evolution

    • Open Access
      Fluctuations uncover a distinct class of traveling waves
      Gabriel Birzu, Oskar Hallatschek, and Kirill S. Korolev
      PNAS April 17, 2018 115 (16) E3645-E3654; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1715737115
    • You have access
      Energetic tradeoffs control the size distribution of aquatic mammals
      • From the Cover
      William Gearty, Craig R. McClain, and Jonathan L. Payne
      PNAS April 17, 2018 115 (16) 4194-4199; published ahead of print March 26, 2018. https://doi.org/10.1073/pnas.1712629115
    • Open Access
      Impact of the tree prior on estimating clock rates during epidemic outbreaks
      Simon Möller, Louis du Plessis, and Tanja Stadler
      PNAS April 17, 2018 115 (16) 4200-4205; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1713314115
  • Genetics

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      Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase
      Samuel K. McBrayer, Benjamin A. Olenchock, Gabriel J. DiNatale, Diana D. Shi, Januka Khanal, Rebecca B. Jennings, Jesse S. Novak, Matthew G. Oser, Alissa K. Robbins, Rebecca Modiste, Dennis Bonal, Javid Moslehi, Roderick T. Bronson, Donna Neuberg, Quang-De Nguyen, Sabina Signoretti, Julie-Aurore Losman, and William G. Kaelin Jr.
      PNAS April 17, 2018 115 (16) E3741-E3748; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1716029115
    • Open Access
      Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts
      Amanda J. DuBose, Stephen T. Lichtenstein, Noreen M. Petrash, Michael R. Erdos, Leslie B. Gordon, and Francis S. Collins
      PNAS April 17, 2018 115 (16) 4206-4211; published ahead of print March 26, 2018. https://doi.org/10.1073/pnas.1802811115
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      High-accuracy lagging-strand DNA replication mediated by DNA polymerase dissociation
      Katarzyna H. Maslowska, Karolina Makiela-Dzbenska, Jin-Yao Mo, Iwona J. Fijalkowska, and Roel M. Schaaper
      PNAS April 17, 2018 115 (16) 4212-4217; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1720353115
    • You have access
      Transcriptional mutagenesis mediated by 8-oxoG induces translational errors in mammalian cells
      Da-Peng Dai, Wei Gan, Hiroshi Hayakawa, Jia-Lou Zhu, Xiu-Qing Zhang, Guo-Xin Hu, Tao Xu, Zhe-Li Jiang, Li-Qun Zhang, Xue-Da Hu, Ben Nie, Yue Zhou, Jin Li, Xiao-Yang Zhou, Jian Li, Tie-Mei Zhang, Qing He, Dong-Ge Liu, Hai-Bo Chen, Nan Yang, Ping-Ping Zuo, Zhi-Xin Zhang, Huan-Ming Yang, Yao Wang, Samuel H. Wilson, Yi-Xin Zeng, Jian-Ye Wang, Mutsuo Sekiguchi, and Jian-Ping Cai
      PNAS April 17, 2018 115 (16) 4218-4222; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1718363115
  • Medical Sciences

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      Interrelated role of Klotho and calcium-sensing receptor in parathyroid hormone synthesis and parathyroid hyperplasia
      Yi Fan, Weiqing Liu, Ruiye Bi, Michael J. Densmore, Tadatoshi Sato, Michael Mannstadt, Quan Yuan, Xuedong Zhou, Hannes Olauson, Tobias E. Larsson, Hakan R. Toka, Martin R. Pollak, Edward M. Brown, and Beate Lanske
      PNAS April 17, 2018 115 (16) E3749-E3758; published ahead of print April 4, 2018. https://doi.org/10.1073/pnas.1717754115
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      FAM210A is a novel determinant of bone and muscle structure and strength
      Ken-ichiro Tanaka, Yingben Xue, Loan Nguyen-Yamamoto, John A. Morris, Ippei Kanazawa, Toshitsugu Sugimoto, Simon S. Wing, J. Brent Richards, and David Goltzman
      PNAS April 17, 2018 115 (16) E3759-E3768; published ahead of print April 4, 2018. https://doi.org/10.1073/pnas.1719089115
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      Targeting galectin-1 inhibits pancreatic cancer progression by modulating tumor–stroma crosstalk
      Carlos A. Orozco, Neus Martinez-Bosch, Pedro E. Guerrero, Judith Vinaixa, Tomás Dalotto-Moreno, Mar Iglesias, Mireia Moreno, Magdolna Djurec, Françoise Poirier, Hans-Joachim Gabius, Martin E. Fernandez-Zapico, Rosa F. Hwang, Carmen Guerra, Gabriel A. Rabinovich, and Pilar Navarro
      PNAS April 17, 2018 115 (16) E3769-E3778; published ahead of print April 3, 2018. https://doi.org/10.1073/pnas.1722434115
    • Open Access
      Learned immunosuppressive placebo responses in renal transplant patients
      Julia Kirchhof, Liubov Petrakova, Alexandra Brinkhoff, Sven Benson, Justine Schmidt, Maike Unteroberdörster, Benjamin Wilde, Ted J. Kaptchuk, Oliver Witzke, and Manfred Schedlowski
      PNAS April 17, 2018 115 (16) 4223-4227; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1720548115
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      Ablation of insulin receptor substrates 1 and 2 suppresses Kras-driven lung tumorigenesis
      He Xu, Min-Sik Lee, Pei-Yun Tsai, Ashley S. Adler, Natasha L. Curry, Saketh Challa, Elizaveta Freinkman, Daniel S. Hitchcock, Kyle D. Copps, Morris F. White, Roderick T. Bronson, Michael Marcotrigiano, Yaotang Wu, Clary B. Clish, and Nada Y. Kalaany
      PNAS April 17, 2018 115 (16) 4228-4233; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1718414115
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      Intron retention induced by microsatellite expansions as a disease biomarker
      Łukasz J. Sznajder, James D. Thomas, Ellie M. Carrell, Tammy Reid, Karen N. McFarland, John D. Cleary, Ruan Oliveira, Curtis A. Nutter, Kirti Bhatt, Krzysztof Sobczak, Tetsuo Ashizawa, Charles A. Thornton, Laura P. W. Ranum, and Maurice S. Swanson
      PNAS April 17, 2018 115 (16) 4234-4239; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1716617115
  • Microbiology

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      The Vibrio cholerae type VI secretion system can modulate host intestinal mechanics to displace gut bacterial symbionts
      Savannah L. Logan, Jacob Thomas, Jinyuan Yan, Ryan P. Baker, Drew S. Shields, Joao B. Xavier, Brian K. Hammer, and Raghuveer Parthasarathy
      PNAS April 17, 2018 115 (16) E3779-E3787; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1720133115
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      Plasticity in early immune evasion strategies of a bacterial pathogen
      Quentin Bernard, Alexis A. Smith, Xiuli Yang, Juraj Koci, Shelby D. Foor, Sarah D. Cramer, Xuran Zhuang, Jennifer E. Dwyer, Yi-Pin Lin, Emmanuel F. Mongodin, Adriana Marques, John M. Leong, Juan Anguita, and Utpal Pal
      PNAS April 17, 2018 115 (16) E3788-E3797; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1718595115
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      SAMHD1 suppresses innate immune responses to viral infections and inflammatory stimuli by inhibiting the NF-κB and interferon pathways
      Shuliang Chen, Serena Bonifati, Zhihua Qin, Corine St. Gelais, Karthik M. Kodigepalli, Bradley S. Barrett, Sun Hee Kim, Jenna M. Antonucci, Katherine J. Ladner, Olga Buzovetsky, Kirsten M. Knecht, Yong Xiong, Jacob S. Yount, Denis C. Guttridge, Mario L. Santiago, and Li Wu
      PNAS April 17, 2018 115 (16) E3798-E3807; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1801213115
    • Open Access
      Multiple nuclear-replicating viruses require the stress-induced protein ZC3H11A for efficient growth
      Shady Younis, Wael Kamel, Tina Falkeborn, Hao Wang, Di Yu, Robert Daniels, Magnus Essand, Jorma Hinkula, Göran Akusjärvi, and Leif Andersson
      PNAS April 17, 2018 115 (16) E3808-E3816; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1722333115
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      A small-molecule fragment that emulates binding of receptor and broadly neutralizing antibodies to influenza A hemagglutinin
      Rameshwar U. Kadam and Ian A. Wilson
      PNAS April 17, 2018 115 (16) 4240-4245; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1801999115
    • Open Access
      Flavivirus internalization is regulated by a size-dependent endocytic pathway
      Brent A. Hackett and Sara Cherry
      PNAS April 17, 2018 115 (16) 4246-4251; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1720032115
  • Neuroscience

    • Open Access
      Spatial eye–hand coordination during bimanual reaching is not systematically coded in either LIP or PRR
      Eric Mooshagian and Lawrence H. Snyder
      PNAS April 17, 2018 115 (16) E3817-E3826; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1718267115
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      Identification of long-lived synaptic proteins by proteomic analysis of synaptosome protein turnover
      Seok Heo, Graham H. Diering, Chan Hyun Na, Raja Sekhar Nirujogi, Julia L. Bachman, Akhilesh Pandey, and Richard L. Huganir
      PNAS April 17, 2018 115 (16) E3827-E3836; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1720956115
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      Characterizing the human hippocampus in aging and Alzheimer’s disease using a computational atlas derived from ex vivo MRI and histology
      Daniel H. Adler, Laura E. M. Wisse, Ranjit Ittyerah, John B. Pluta, Song-Lin Ding, Long Xie, Jiancong Wang, Salmon Kadivar, John L. Robinson, Theresa Schuck, John Q. Trojanowski, Murray Grossman, John A. Detre, Mark A. Elliott, Jon B. Toledo, Weixia Liu, Stephen Pickup, Michael I. Miller, Sandhitsu R. Das, David A. Wolk, and Paul A. Yushkevich
      PNAS April 17, 2018 115 (16) 4252-4257; published ahead of print March 28, 2018. https://doi.org/10.1073/pnas.1801093115
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      Second-order spinal cord pathway contributes to cortical responses after long recoveries from dorsal column injury in squirrel monkeys
      Chia-Chi Liao, Jamie L. Reed, Hui-Xin Qi, Eva K. Sawyer, and Jon H. Kaas
      PNAS April 17, 2018 115 (16) 4258-4263; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1718826115
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      Psychophysical evidence for auditory motion parallax
      • From the Cover
      Daria Genzel, Michael Schutte, W. Owen Brimijoin, Paul R. MacNeilage, and Lutz Wiegrebe
      PNAS April 17, 2018 115 (16) 4264-4269; published ahead of print March 12, 2018. https://doi.org/10.1073/pnas.1712058115
    • Open Access
      Ectopic neurogenesis induced by prenatal antiepileptic drug exposure augments seizure susceptibility in adult mice
      Atsuhiko Sakai, Taito Matsuda, Hiroyoshi Doi, Yukiko Nagaishi, Kiyoko Kato, and Kinichi Nakashima
      PNAS April 17, 2018 115 (16) 4270-4275; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1716479115
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      Long-term in vivo recording of circadian rhythms in brains of freely moving mice
      Long Mei, Yanyan Fan, Xiaohua Lv, David K. Welsh, Cheng Zhan, and Eric Erquan Zhang
      PNAS April 17, 2018 115 (16) 4276-4281; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1717735115
  • Pharmacology

    • Open Access
      Activation of AMPK by metformin improves withdrawal signs precipitated by nicotine withdrawal
      Julia K. Brynildsen, Bridgin G. Lee, Isaac J. Perron, Sunghee Jin, Sangwon F. Kim, and Julie A. Blendy
      PNAS April 17, 2018 115 (16) 4282-4287; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1707047115
  • Plant Biology

    • You have access
      Negative regulator of E2F transcription factors links cell cycle checkpoint and DNA damage repair
      Lili Wang, Hanchen Chen, Chongyang Wang, Zhenjie Hu, and Shunping Yan
      PNAS April 17, 2018 115 (16) E3837-E3845; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1720094115
    • Open Access
      Phytophthora palmivora establishes tissue-specific intracellular infection structures in the earliest divergent land plant lineage
      Philip Carella, Anna Gogleva, Marta Tomaselli, Carolin Alfs, and Sebastian Schornack
      PNAS April 17, 2018 115 (16) E3846-E3855; published ahead of print April 3, 2018. https://doi.org/10.1073/pnas.1717900115
  • Sustainability Science

    • You have access
      Effects of national ecological restoration projects on carbon sequestration in China from 2001 to 2010
      Fei Lu, Huifeng Hu, Wenjuan Sun, Jiaojun Zhu, Guobin Liu, Wangming Zhou, Quanfa Zhang, Peili Shi, Xiuping Liu, Xing Wu, Lu Zhang, Xiaohua Wei, Limin Dai, Kerong Zhang, Yirong Sun, Sha Xue, Wanjun Zhang, Dingpeng Xiong, Lei Deng, Bojie Liu, Li Zhou, Chao Zhang, Xiao Zheng, Jiansheng Cao, Yao Huang, Nianpeng He, Guoyi Zhou, Yongfei Bai, Zongqiang Xie, Zhiyao Tang, Bingfang Wu, Jingyun Fang, Guohua Liu, and Guirui Yu
      PNAS April 17, 2018 115 (16) 4039-4044; https://doi.org/10.1073/pnas.1700294115
  • Systems Biology

    • You have access
      Robust, linear correlations between growth rates and β-lactam–mediated lysis rates
      Anna J. Lee, Shangying Wang, Hannah R. Meredith, Bihan Zhuang, Zhuojun Dai, and Lingchong You
      PNAS April 17, 2018 115 (16) 4069-4074; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1719504115
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      Role of metabolic spatiotemporal dynamics in regulating biofilm colony expansion
      Federico Bocci, Yoko Suzuki, Mingyang Lu, and José N. Onuchic
      PNAS April 17, 2018 115 (16) 4288-4293; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1706920115

Corrections (Online Only)

  • You have access
    Correction for Ramus et al,. An invasive foundation species enhances multifunctionality in a coastal ecosystem
    PNAS April 17, 2018 115 (16) E3856; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1804651115
  • You have access
    Correction for Chen et al., B7-H1 maintains the polyclonal T cell response by protecting dendritic cells from cytotoxic T lymphocyte destruction
    PNAS April 17, 2018 115 (16) E3857; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1804362115
  • You have access
    Correction for Li et al., Regulator of G protein signaling 5 protects against cardiac hypertrophy and fibrosis during biomechanical stress of pressure overload
    PNAS April 17, 2018 115 (16) E3858-E3861; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1804573115
  • You have access
    Correction for Itkin et al., The biosynthetic pathway of the nonsugar, high-intensity sweetener mogroside V from Siraitia grosvenorii
    PNAS April 17, 2018 115 (16) E3862; published ahead of print April 2, 2018. https://doi.org/10.1073/pnas.1804875115
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Proceedings of the National Academy of Sciences: 115 (16)
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