Multiple nuclear-replicating viruses require the stress-induced protein ZC3H11A for efficient growth

^aDepartment of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden;
^bDepartment of Animal Production, Ain Shams University, Shoubra El-Kheima, 11241 Cairo, Egypt;
^cDepartment of Clinical and Experimental Medicine, Linköping University, SE-58183 Linköping, Sweden;
^dDepartment of Biochemistry and Biophysics, Stockholm University, SE-10691 Stockholm, Sweden;
^eDepartment of Immunology, Genetics and Pathology, Uppsala University, SE-751 23 Uppsala, Sweden;
^fDepartment of Animal Breeding and Genetics, Swedish University of Agricultural Sciences, SE-75007 Uppsala, Sweden;
^gDepartment of Veterinary Integrative Biosciences, Texas A&M University, College Station, TX 77483

Contributed by Leif Andersson, February 22, 2018 (sent for review December 22, 2017; reviewed by Phillip A. Sharp and Joan A. Steitz)

Footnotes

↵¹S.Y. and W.K. contributed equally to this work.
↵²To whom correspondence may be addressed. Email: goran.akusjarvi{at}imbim.uu.se or leif.andersson{at}imbim.uu.se.

Author contributions: S.Y., W.K., G.A., and L.A. designed research; S.Y., W.K., T.F., H.W., and D.Y. performed research; S.Y., W.K., T.F., H.W., D.Y., R.D., M.E., J.H., G.A., and L.A. analyzed data; and S.Y., W.K., G.A., and L.A. wrote the paper.
Reviewers: P.A.S., Massachusetts Institute of Technology; and J.A.S., Yale University/Howard Hughes Medical Institute.
Conflict of interest statement: S.Y., W.K., G.A., and L.A. are coauthors on a patent application filed based on some of the results in this study.
Data deposition: The RNA-seq data have been deposited in the NCBI Sequence Read Archive (accession no. SRP133853).
This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1722333115/-/DCSupplemental.