Nucleus-specific expression in the multinuclear mushroom-forming fungus Agaricus bisporus reveals different nuclear regulatory programs

New Research In

Edited by Mitsuhiro Yanagida, Okinawa Institute of Science and Technology Graduate University, Onna-Son, Kunigami, Japan, and approved March 22, 2018 (received for review December 13, 2017)

vol. 115 no. 17 4429-4434

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^aDelft Bioinformatics Lab, Delft University of Technology, 2628XE Delft, The Netherlands;
^bMicrobiology, Utrecht University, 3584CH Utrecht, The Netherlands;
^cPlant Breeding, Wageningen University and Research, 6708PB Wageningen, The Netherlands;
^dBroad Institute of MIT and Harvard, Cambridge, MA 02142

Edited by Mitsuhiro Yanagida, Okinawa Institute of Science and Technology Graduate University, Onna-Son, Kunigami, Japan, and approved March 22, 2018 (received for review December 13, 2017)

↵¹To whom correspondence may be addressed. Email: t.abeel{at}tudelft.nl or t.gehrmann{at}tudelft.nl.
↵²Present address: Department of Biotechnology, Delft University of Technology, 2629 HZ Delft, The Netherlands.

Author contributions: T.G., H.A.B.W., M.J.T.R., and T.A. designed research; T.G., J.F.P., R.A.O., A.M.V., A.S.M.S., J.J.P.B., H.A.B.W., M.J.T.R., and T.A. performed research; T.G. and R.A.O. analyzed data; and T.G., H.A.B.W., M.J.T.R., and T.A. wrote the paper.
The authors declare no conflict of interest.
This article is a PNAS Direct Submission.
Data deposition: Methylation data have been deposited in the Sequence Read Archive (accession no. SAMN06284058).
This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1721381115/-/DCSupplemental.