Wireless, intraoral hybrid electronics for real-time quantification of sodium intake toward hypertension management

^aGeorge W. Woodruff School of Mechanical Engineering, College of Engineering, Georgia Institute of Technology, Atlanta, GA 30332;
^bDepartment of Mechanical and Nuclear Engineering, School of Engineering, Virginia Commonwealth University, Richmond, VA 23284;
^cDepartment of Chemical and Biomolecular Engineering, Chonnam National University, 59626 Jeonnam, South Korea;
^dDepartment of Prosthodontics, School of Dentistry, Virginia Commonwealth University, Richmond, VA 23298;
^eDepartment of Industrial Engineering, University of Pittsburgh, Pittsburgh, PA 15261;
^fDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15261;
^gDepartment of Physiology and Biophysics, School of Medicine, Virginia Commonwealth University, Richmond, VA 23298;
^hInstitute for Electronics and Nanotechnology, Georgia Institute of Technology, Atlanta, GA 30332;
ⁱPetit Institute for Bioengineering & Bioscience, Georgia Institute of Technology, Atlanta, GA 30332;
^jCenter for Flexible Electronics, Georgia Institute of Technology, Atlanta, GA 30332

Edited by John A. Rogers, Northwestern University, Evanston, IL, and approved April 11, 2018 (received for review November 13, 2017)

Footnotes

Author contributions: Y.L., J.P.C., R.M.C., and W.-H.Y. designed research; Y.L., C.H., S.M., D.S.L., M.M., M.P., Y.K., K.T., J.P.C., M.S., Y.C., and W.-H.Y. performed research; Y.L., C.H., S.M., D.S.L., M.M., M.P., Y.K., K.T., H.-S.B., M.S., Y.C., R.M.C., and W.-H.Y. analyzed data; and Y.L., C.H., H.-S.B., Y.C., R.M.C., and W.-H.Y. wrote the paper.
Conflict of interest statement: R.M.C. and W.-H.Y. are inventors on Patent Application US 2017/0087363A1 that covers “Wireless implantable taste system.” The other authors declare that they have no competing financial interests.
This article is a PNAS Direct Submission.
This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1719573115/-/DCSupplemental.