Structure of an EIIC sugar transporter trapped in an inward-facing conformation

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Edited by Ernest M. Wright, David Geffen School of Medicine at UCLA, Los Angeles, CA, and approved April 30, 2018 (received for review January 12, 2018)

vol. 115 no. 23 5962-5967

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^aDepartment of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030;
^bDepartment of Biological Sciences, Lehigh University, Bethlehem, PA 18015;
^cDepartment of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX 77030;
^dKunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China

Edited by Ernest M. Wright, David Geffen School of Medicine at UCLA, Los Angeles, CA, and approved April 30, 2018 (received for review January 12, 2018)

↵¹Z.R. and J.L. contributed equally to this work.
↵²To whom correspondence may be addressed. Email: mzhou{at}bcm.edu, allan.ferreon{at}bcm.edu, or woi216{at}lehigh.edu.

Author contributions: Z.R., J.L., M.M.M., Y.N., L.H., Z.X., J.G.M., A.C.M.F., W.I., and M.Z. designed research, collected and analyzed data, and wrote the paper.
The authors declare no conflict of interest.
This article is a PNAS Direct Submission.
Data deposition: The atomic coordinates and structure factors have been deposited in the Protein Data Bank, www.wwpdb.org (PDB ID code 6BVG).
This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1800647115/-/DCSupplemental.