Proceedings of the National Academy of Sciences: 115 (25)

New Research In

June 19, 2018; vol. 115 no. 25

This Week in PNAS

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In This Issue
PNAS June 19, 2018 115 (25) 6315-6317; https://doi.org/10.1073/iti2518115

Letters (Online Only)

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Morality traits still dominate in forming impressions of others
Justin F. Landy, Jared Piazza, and Geoffrey P. Goodwin

PNAS June 19, 2018 115 (25) E5636; published ahead of print June 11, 2018. https://doi.org/10.1073/pnas.1807096115
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Reply to Landy et al.: Terms and conditions may apply
David E. Melnikoff and April H. Bailey

PNAS June 19, 2018 115 (25) E5637-E5638; published ahead of print June 11, 2018. https://doi.org/10.1073/pnas.1807699115
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Pharmacogenomics of antioxidant supplementation to prevent age-related macular degeneration
Andrew J. Vickers

PNAS June 19, 2018 115 (25) E5639; published ahead of print June 7, 2018. https://doi.org/10.1073/pnas.1803536115
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Reply to Vickers: Pharmacogenetics and progression to neovascular age-related macular degeneration—Evidence supporting practice change
Demetrios G. Vavvas, Kent W. Small, Carl Awh, Brent W. Zanke, Robert J. Tibshirani, and Rafal Kustra

PNAS June 19, 2018 115 (25) E5640-E5641; published ahead of print June 7, 2018. https://doi.org/10.1073/pnas.1804781115

Opinion

Leading scientists discuss current issues.

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Opinion: Medical misinformation in the era of Google: Computational approaches to a pervasive problem
Front Matter
Scott R. Granter and David J. Papke Jr.

PNAS June 19, 2018 115 (25) 6318-6321; https://doi.org/10.1073/pnas.1808264115

Commentaries

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Fatty acid chemical mediator provides insights into the pathology and treatment of Parkinson’s disease
Cesar V. Borlongan

PNAS June 19, 2018 115 (25) 6322-6324; published ahead of print May 30, 2018. https://doi.org/10.1073/pnas.1807276115
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Time to build on good design: Resolving the temporal dynamics of gene regulatory networks
Kathleen Greenham and C. Robertson McClung

PNAS June 19, 2018 115 (25) 6325-6327; published ahead of print June 5, 2018. https://doi.org/10.1073/pnas.1807707115
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The scale of life and its lessons for humanity
Matthew G. Burgess and Steven D. Gaines

PNAS June 19, 2018 115 (25) 6328-6330; published ahead of print May 23, 2018. https://doi.org/10.1073/pnas.1807019115

PNAS Plus Significance Statements

Brief statements written by the authors about the significance of their papers.

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PNAS Plus Significance Statements
PNAS June 19, 2018 115 (25) 6331-6334; https://doi.org/10.1073/pnas.ss11525

Physical Sciences

Applied Physical Sciences
- Open Access
  High-resolution μCT of a mouse embryo using a compact laser-driven X-ray betatron source
  Jason M. Cole, Daniel R. Symes, Nelson C. Lopes, Jonathan C. Wood, Kristjan Poder, Saleh Alatabi, Stanley W. Botchway, Peta S. Foster, Sarah Gratton, Sara Johnson, Christos Kamperidis, Olena Kononenko, Michael De Lazzari, Charlotte A. J. Palmer, Dean Rusby, Jeremy Sanderson, Michael Sandholzer, Gianluca Sarri, Zsombor Szoke-Kovacs, Lydia Teboul, James M. Thompson, Jonathan R. Warwick, Henrik Westerberg, Mark A. Hill, Dominic P. Norris, Stuart P. D. Mangles, and Zulfikar Najmudin
  
  PNAS June 19, 2018 115 (25) 6335-6340; published ahead of print June 5, 2018. https://doi.org/10.1073/pnas.1802314115
Biophysics and Computational Biology
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  Robust nonequilibrium pathways to microcompartment assembly
  Grant M. Rotskoff and Phillip L. Geissler
  
  PNAS June 19, 2018 115 (25) 6341-6346; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1802499115
Chemistry
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  Water agglomerates on Fe₃O₄(001)
  Matthias Meier, Jan Hulva, Zdeněk Jakub, Jiří Pavelec, Martin Setvin, Roland Bliem, Michael Schmid, Ulrike Diebold, Cesare Franchini, and Gareth S. Parkinson
  
  PNAS June 19, 2018 115 (25) E5642-E5650; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1801661115
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  Simultaneous cancer and tumor microenvironment subtyping using confocal infrared microscopy for all-digital molecular histopathology
  Shachi Mittal, Kevin Yeh, L. Suzanne Leslie, Seth Kenkel, Andre Kajdacsy-Balla, and Rohit Bhargava
  
  PNAS June 19, 2018 115 (25) E5651-E5660; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1719551115
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  Distinguishing malignant from benign microscopic skin lesions using desorption electrospray ionization mass spectrometry imaging
  Katherine Margulis, Albert S. Chiou, Sumaira Z. Aasi, Robert J. Tibshirani, Jean Y. Tang, and Richard N. Zare
  
  PNAS June 19, 2018 115 (25) 6347-6352; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1803733115
Computer Sciences
- Open Access
  Automatically identifying, counting, and describing wild animals in camera-trap images with deep learning
  From the Cover
  
  Mohammad Sadegh Norouzzadeh, Anh Nguyen, Margaret Kosmala, Alexandra Swanson, Meredith S. Palmer, Craig Packer, and Jeff Clune
  
  PNAS June 19, 2018 115 (25) E5716-E5725; published ahead of print June 5, 2018. https://doi.org/10.1073/pnas.1719367115
Earth, Atmospheric, and Planetary Sciences
- Open Access
  Exceptionally high levels of lead pollution in the Balkans from the Early Bronze Age to the Industrial Revolution
  Jack Longman, Daniel Veres, Walter Finsinger, and Vasile Ersek
  
  PNAS June 19, 2018 115 (25) E5661-E5668; published ahead of print May 29, 2018. https://doi.org/10.1073/pnas.1721546115
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  Potassic, high-silica Hadean crust
  From the Cover
  
  Patrick Boehnke, Elizabeth A. Bell, Thomas Stephan, Reto Trappitsch, C. Brenhin Keller, Olivia S. Pardo, Andrew M. Davis, T. Mark Harrison, and Michael J. Pellin
  
  PNAS June 19, 2018 115 (25) 6353-6356; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1720880115
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  Pronounced summer warming in northwest Greenland during the Holocene and Last Interglacial
  Jamie M. McFarlin, Yarrow Axford, Magdalena R. Osburn, Meredith A. Kelly, Erich C. Osterberg, and Lauren B. Farnsworth
  
  PNAS June 19, 2018 115 (25) 6357-6362; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1720420115
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  Proterozoic Milankovitch cycles and the history of the solar system
  Stephen R. Meyers and Alberto Malinverno
  
  PNAS June 19, 2018 115 (25) 6363-6368; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1717689115
Engineering
- Open Access
  Modulating cell state to enhance suspension expansion of human pluripotent stem cells
  Yonatan Y. Lipsitz, Curtis Woodford, Ting Yin, Jacob H. Hanna, and Peter W. Zandstra
  
  PNAS June 19, 2018 115 (25) 6369-6374; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1714099115
Physics
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  Configuration correlation governs slow dynamics of supercooled metallic liquids
  Yuan-Chao Hu, Yan-Wei Li, Yong Yang, Peng-Fei Guan, Hai-Yang Bai, and Wei-Hua Wang
  
  PNAS June 19, 2018 115 (25) 6375-6380; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1802300115
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  Beating the classical precision limit with spin-1 Dicke states of more than 10,000 atoms
  Yi-Quan Zou, Ling-Na Wu, Qi Liu, Xin-Yu Luo, Shuai-Feng Guo, Jia-Hao Cao, Meng Khoon Tey, and Li You
  
  PNAS June 19, 2018 115 (25) 6381-6385; published ahead of print June 1, 2018. https://doi.org/10.1073/pnas.1715105115
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  Reciprocal space tomography of 3D skyrmion lattice order in a chiral magnet
  Shilei Zhang, Gerrit van der Laan, Jan Müller, Lukas Heinen, Markus Garst, Andreas Bauer, Helmuth Berger, Christian Pfleiderer, and Thorsten Hesjedal
  
  PNAS June 19, 2018 115 (25) 6386-6391; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1803367115

Biological Sciences

Applied Biological Sciences
- Open Access
  Modulating cell state to enhance suspension expansion of human pluripotent stem cells
  Yonatan Y. Lipsitz, Curtis Woodford, Ting Yin, Jacob H. Hanna, and Peter W. Zandstra
  
  PNAS June 19, 2018 115 (25) 6369-6374; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1714099115
Biochemistry
- Open Access
  Targeting the potent Beclin 1–UVRAG coiled-coil interaction with designed peptides enhances autophagy and endolysosomal trafficking
  Shuai Wu, Yunjiao He, Xianxiu Qiu, Wenchao Yang, Wenchao Liu, Xiaohua Li, Yan Li, Han-Ming Shen, Renxiao Wang, Zhenyu Yue, and Yanxiang Zhao
  
  PNAS June 19, 2018 115 (25) E5669-E5678; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1721173115
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  A folded viral noncoding RNA blocks host cell exoribonucleases through a conformationally dynamic RNA structure
  Anna-Lena Steckelberg, Benjamin M. Akiyama, David A. Costantino, Tim L. Sit, Jay C. Nix, and Jeffrey S. Kieft
  
  PNAS June 19, 2018 115 (25) 6404-6409; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1802429115
Biophysics and Computational Biology
- Open Access
  Individuality and slow dynamics in bacterial growth homeostasis
  Lee Susman, Maryam Kohram, Harsh Vashistha, Jeffrey T. Nechleba, Hanna Salman, and Naama Brenner
  
  PNAS June 19, 2018 115 (25) E5679-E5687; published ahead of print June 5, 2018. https://doi.org/10.1073/pnas.1615526115
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  Robust nonequilibrium pathways to microcompartment assembly
  Grant M. Rotskoff and Phillip L. Geissler
  
  PNAS June 19, 2018 115 (25) 6341-6346; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1802499115
Cell Biology
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  In vitro biomimetic engineering of a human hematopoietic niche with functional properties
  Paul E. Bourgine, Thibaut Klein, Anna M. Paczulla, Takafumi Shimizu, Leo Kunz, Konstantinos D. Kokkaliaris, Daniel L. Coutu, Claudia Lengerke, Radek Skoda, Timm Schroeder, and Ivan Martin
  
  PNAS June 19, 2018 115 (25) E5688-E5695; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1805440115
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  Spatially modulated ephrinA1:EphA2 signaling increases local contractility and global focal adhesion dynamics to promote cell motility
  Zhongwen Chen, Dongmyung Oh, Kabir H. Biswas, Cheng-Han Yu, Ronen Zaidel-Bar, and Jay T. Groves
  
  PNAS June 19, 2018 115 (25) E5696-E5705; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1719961115
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  Minimizing ATP depletion by oxygen scavengers for single-molecule fluorescence imaging in live cells
  Seung-Ryoung Jung, Yi Deng, Christopher Kushmerick, Charles L. Asbury, Bertil Hille, and Duk-Su Koh
  
  PNAS June 19, 2018 115 (25) E5706-E5715; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1717724115
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  Altered p53 functionality in cancer-associated fibroblasts contributes to their cancer-supporting features
  Sharathchandra Arandkar, Noa Furth, Yair Elisha, Nishanth Belugali Nataraj, Heiko van der Kuip, Yosef Yarden, Walter Aulitzky, Igor Ulitsky, Benjamin Geiger, and Moshe Oren
  
  PNAS June 19, 2018 115 (25) 6410-6415; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1719076115
Ecology
- Open Access
  Automatically identifying, counting, and describing wild animals in camera-trap images with deep learning
  From the Cover
  
  Mohammad Sadegh Norouzzadeh, Anh Nguyen, Margaret Kosmala, Alexandra Swanson, Meredith S. Palmer, Craig Packer, and Jeff Clune
  
  PNAS June 19, 2018 115 (25) E5716-E5725; published ahead of print June 5, 2018. https://doi.org/10.1073/pnas.1719367115
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  Distance-dependent defensive coloration in the poison frog Dendrobates tinctorius, Dendrobatidae
  James B. Barnett, Constantine Michalis, Nicholas E. Scott-Samuel, and Innes C. Cuthill
  
  PNAS June 19, 2018 115 (25) 6416-6421; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1800826115
- Open Access
  Exploitation drives an ontogenetic-like deepening in marine fish
  Kenneth T. Frank, Brian Petrie, William C. Leggett, and Daniel G. Boyce
  
  PNAS June 19, 2018 115 (25) 6422-6427; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1802096115
Evolution
- Open Access
  Directed evolution of multiple genomic loci allows the prediction of antibiotic resistance
  Ákos Nyerges, Bálint Csörgő, Gábor Draskovits, Bálint Kintses, Petra Szili, Györgyi Ferenc, Tamás Révész, Eszter Ari, István Nagy, Balázs Bálint, Bálint Márk Vásárhelyi, Péter Bihari, Mónika Számel, Dávid Balogh, Henrietta Papp, Dorottya Kalapis, Balázs Papp, and Csaba Pál
  
  PNAS June 19, 2018 115 (25) E5726-E5735; published ahead of print June 5, 2018. https://doi.org/10.1073/pnas.1801646115
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  Evolutionary convergence in lignin-degrading enzymes
  Iván Ayuso-Fernández, Francisco J. Ruiz-Dueñas, and Angel T. Martínez
  
  PNAS June 19, 2018 115 (25) 6428-6433; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1802555115
Immunology and Inflammation
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  Cell-intrinsic regulation of murine epidermal Langerhans cells by protein S
  Yaara Tabib, Nora S. Jaber, Maria Nassar, Tal Capucha, Gabriel Mizraji, Tsipora Nir, Noam Koren, Itay Aizenbud, Avraham Maimon, Luba Eli-Berchoer, Asaf Wilensky, Tal Burstyn-Cohen, and Avi-Hai Hovav
  
  PNAS June 19, 2018 115 (25) E5736-E5745; published ahead of print June 5, 2018. https://doi.org/10.1073/pnas.1800303115
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  BP180 dysfunction triggers spontaneous skin inflammation in mice
  Yang Zhang, Bin-Jin Hwang, Zhen Liu, Ning Li, Kendall Lough, Scott E. Williams, Jinbo Chen, Susan W. Burette, Luis A. Diaz, Maureen A. Su, Shengxiang Xiao, and Zhi Liu
  
  PNAS June 19, 2018 115 (25) 6434-6439; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1721805115
Medical Sciences
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  Gastrointestinal stromal tumor enhancers support a transcription factor network predictive of clinical outcome
  Matthew L. Hemming, Matthew A. Lawlor, Rhamy Zeid, Tom Lesluyes, Jonathan A. Fletcher, Chandrajit P. Raut, Ewa T. Sicinska, Frédéric Chibon, Scott A. Armstrong, George D. Demetri, and James E. Bradner
  
  PNAS June 19, 2018 115 (25) E5746-E5755; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1802079115
- Open Access
  A stress-induced response complex (SIRC) shuttles miRNAs, siRNAs, and oligonucleotides to the nucleus
  Daniela Castanotto, Xiaowei Zhang, Jessica Alluin, Xizhe Zhang, Jacqueline Rüger, Brian Armstrong, John Rossi, Arthur Riggs, and C. A. Stein
  
  PNAS June 19, 2018 115 (25) E5756-E5765; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1721346115
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  PHIP as a therapeutic target for driver-negative subtypes of melanoma, breast, and lung cancer
  David de Semir, Vladimir Bezrookove, Mehdi Nosrati, Altaf A. Dar, Clayton Wu, Julia Shen, Christopher Rieken, Meenakshi Venkatasubramanian, James R. Miller III, Pierre-Yves Desprez, Sean McAllister, Liliana Soroceanu, Robert J. Debs, Nathan Salomonis, Dirk Schadendorf, James E. Cleaver, and Mohammed Kashani-Sabet
  
  PNAS June 19, 2018 115 (25) E5766-E5775; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1804779115
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  Trends in health inequalities in 27 European countries
  Johan P. Mackenbach, José Rubio Valverde, Barbara Artnik, Matthias Bopp, Henrik Brønnum-Hansen, Patrick Deboosere, Ramune Kalediene, Katalin Kovács, Mall Leinsalu, Pekka Martikainen, Gwenn Menvielle, Enrique Regidor, Jitka Rychtaříková, Maica Rodriguez-Sanz, Paolo Vineis, Chris White, Bogdan Wojtyniak, Yannan Hu, and Wilma J. Nusselder
  
  PNAS June 19, 2018 115 (25) 6440-6445; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1800028115
Microbiology
- Open Access
  ABC transporter content diversity in Streptococcus pneumoniae impacts competence regulation and bacteriocin production
  Charles Y. Wang, Nisha Patel, Wei-Yun Wholey, and Suzanne Dawid
  
  PNAS June 19, 2018 115 (25) E5776-E5785; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1804668115
- Open Access
  Comprehensive skin microbiome analysis reveals the uniqueness of human skin and evidence for phylosymbiosis within the class Mammalia
  Ashley A. Ross, Kirsten M. Müller, J. Scott Weese, and Josh D. Neufeld
  
  PNAS June 19, 2018 115 (25) E5786-E5795; published ahead of print June 5, 2018. https://doi.org/10.1073/pnas.1801302115
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  Regulation of stringent factor by branched-chain amino acids
  Mingxu Fang and Carl E. Bauer
  
  PNAS June 19, 2018 115 (25) 6446-6451; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1803220115
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  Synthetic bottom-up approach reveals the complex interplay of Shigella effectors in regulation of epithelial cell death
  Xiangyu Mou, Skye Souter, Juan Du, Analise Z. Reeves, and Cammie F. Lesser
  
  PNAS June 19, 2018 115 (25) 6452-6457; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1801310115
- Open Access
  Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks
  Filipe De Vadder, Estelle Grasset, Louise Mannerås Holm, Gérard Karsenty, Andrew J. Macpherson, Louise E. Olofsson, and Fredrik Bäckhed
  
  PNAS June 19, 2018 115 (25) 6458-6463; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1720017115
- Open Access
  Small RNA profiling in Mycobacterium tuberculosis identifies MrsI as necessary for an anticipatory iron sparing response
  Elias R. Gerrick, Thibault Barbier, Michael R. Chase, Raylin Xu, Josie François, Vincent H. Lin, Matthew J. Szucs, Jeremy M. Rock, Rushdy Ahmad, Brian Tjaden, Jonathan Livny, and Sarah M. Fortune
  
  PNAS June 19, 2018 115 (25) 6464-6469; published ahead of print June 5, 2018. https://doi.org/10.1073/pnas.1718003115
Neuroscience
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  Stimulation-induced increases in cerebral blood flow and local capillary vasoconstriction depend on conducted vascular responses
  Changsi Cai, Jonas C. Fordsmann, Sofie H. Jensen, Bodil Gesslein, Micael Lønstrup, Bjørn O. Hald, Stefan A. Zambach, Birger Brodin, and Martin J. Lauritzen
  
  PNAS June 19, 2018 115 (25) E5796-E5804; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1707702115
- Open Access
  Rapid, experience-dependent translation of neurogranin enables memory encoding
  Kendrick J. Jones, Sebastian Templet, Khaled Zemoura, Bozena Kuzniewska, Franciso X. Pena, Hongik Hwang, Ding J. Lei, Henny Haensgen, Shannon Nguyen, Christopher Saenz, Michael Lewis, Magdalena Dziembowska, and Weifeng Xu
  
  PNAS June 19, 2018 115 (25) E5805-E5814; published ahead of print June 7, 2018. https://doi.org/10.1073/pnas.1716750115
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  Soluble epoxide hydrolase plays a key role in the pathogenesis of Parkinson’s disease
  From the Cover
  
  Qian Ren, Min Ma, Jun Yang, Risa Nonaka, Akihiro Yamaguchi, Kei-ichi Ishikawa, Kenta Kobayashi, Shigeo Murayama, Sung Hee Hwang, Shinji Saiki, Wado Akamatsu, Nobutaka Hattori, Bruce D. Hammock, and Kenji Hashimoto
  
  PNAS June 19, 2018 115 (25) E5815-E5823; published ahead of print May 7, 2018. https://doi.org/10.1073/pnas.1802179115
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  Human midcingulate cortex encodes distributed representations of task progress
  Clay B. Holroyd, José J. F. Ribas-Fernandes, Danesh Shahnazian, Massimo Silvetti, and Tom Verguts
  
  PNAS June 19, 2018 115 (25) 6398-6403; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1803650115
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  Transdifferentiation of human adult peripheral blood T cells into neurons
  Koji Tanabe, Cheen Euong Ang, Soham Chanda, Victor Hipolito Olmos, Daniel Haag, Douglas F. Levinson, Thomas C. Südhof, and Marius Wernig
  
  PNAS June 19, 2018 115 (25) 6470-6475; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1720273115
- Open Access
  TMS-induced neuronal plasticity enables targeted remodeling of visual cortical maps
  Vladislav Kozyrev, Robert Staadt, Ulf T. Eysel, and Dirk Jancke
  
  PNAS June 19, 2018 115 (25) 6476-6481; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1802798115
Plant Biology
- Open Access
  A shared cis-regulatory module activates transcription in the suspensor of plant embryos
  Kelli F. Henry, Anhthu Q. Bui, Tomokazu Kawashima, and Robert B. Goldberg
  
  PNAS June 19, 2018 115 (25) E5824-E5833; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1805802115
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  Genome-wide regulation of light-controlled seedling morphogenesis by three families of transcription factors
  Hui Shi, Mohan Lyu, Yiwen Luo, Shoucheng Liu, Yue Li, Hang He, Ning Wei, Xing Wang Deng, and Shangwei Zhong
  
  PNAS June 19, 2018 115 (25) 6482-6487; published ahead of print May 29, 2018. https://doi.org/10.1073/pnas.1803861115
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  Uncovering pH at both sides of the root plasma membrane interface using noninvasive imaging
  Alexandre Martinière, Rémy Gibrat, Hervé Sentenac, Xavier Dumont, Isabelle Gaillard, and Nadine Paris
  
  PNAS June 19, 2018 115 (25) 6488-6493; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1721769115
- Open Access
  Temporal transcriptional logic of dynamic regulatory networks underlying nitrogen signaling and use in plants
  From the Cover
  
  Kranthi Varala, Amy Marshall-Colón, Jacopo Cirrone, Matthew D. Brooks, Angelo V. Pasquino, Sophie Léran, Shipra Mittal, Tara M. Rock, Molly B. Edwards, Grace J. Kim, Sandrine Ruffel, W. Richard McCombie, Dennis Shasha, and Gloria M. Coruzzi
  
  PNAS June 19, 2018 115 (25) 6494-6499; published ahead of print May 16, 2018. https://doi.org/10.1073/pnas.1721487115
Psychological and Cognitive Sciences
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  Memory-related hippocampal activation in the sleeping toddler
  Janani Prabhakar, Elliott G. Johnson, Christine Wu Nordahl, and Simona Ghetti
  
  PNAS June 19, 2018 115 (25) 6500-6505; published ahead of print June 4, 2018. https://doi.org/10.1073/pnas.1805572115
Systems Biology
- Open Access
  The biomass distribution on Earth
  From the Cover
  
  Yinon M. Bar-On, Rob Phillips, and Ron Milo
  
  PNAS June 19, 2018 115 (25) 6506-6511; published ahead of print May 21, 2018. https://doi.org/10.1073/pnas.1711842115

Editorial Expression of Concern (Online Only)

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Editorial Expression of Concern: Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice
PNAS June 19, 2018 115 (25) E5834; published ahead of print June 11, 2018. https://doi.org/10.1073/pnas.1808586115

Corrections (Online Only)

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Correction for Zahran et al., Assessment of the Legionnaires’ disease outbreak in Flint, Michigan
PNAS June 19, 2018 115 (25) E5835; published ahead of print June 11, 2018. https://doi.org/10.1073/pnas.1808389115
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Correction for Adam et al., Evolutionary history of carbon monoxide dehydrogenase/acetyl-CoA synthase, one of the oldest enzymatic complexes
PNAS June 19, 2018 115 (25) E5836-E5837; published ahead of print June 11, 2018. https://doi.org/10.1073/pnas.1807540115
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Correction for Oyen et al., Structural basis for antibody recognition of the NANP repeats in Plasmodium falciparum circumsporozoite protein
PNAS June 19, 2018 115 (25) E5838-E5839; published ahead of print June 11, 2018. https://doi.org/10.1073/pnas.1808460115

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