Researchers are exploring whether these ubiquitous fluorinated molecules might worsen infections or hamper vaccine effectiveness.
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Edited by Howard A. Stone, Princeton University, Princeton, NJ, and approved August 15, 2018 (received for review March 11, 2018)
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- Published in issue October 2, 2018.
- Published first September 17, 2018.
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- Previous version (September 17, 2018 - 11:52).
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- Manjima Dhara,
- Jeffrey Nam Lama,
- Tonya Walserb,
- Steven M. Dubinettb,c,d,
- Matthew B. Rettigc,d,e, and
- Dino Di Carloa,d,f,1
- aDepartment of Bioengineering, Samueli School of Engineering, University of California, Los Angeles, CA 90095;
- bDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA 90095;
- cVA Greater Los Angeles Healthcare System, Los Angeles, CA 90073;
- dUCLA Jonsson Comprehensive Cancer Center, Los Angeles, CA 90095;
- eDepartment of Urology, David Geffen School of Medicine, University of California, Los Angeles, CA 90095;
- fDepartment of Mechanical and Aerospace Engineering, Samueli School of Engineering, University of California, Los Angeles, CA 90095
Edited by Howard A. Stone, Princeton University, Princeton, NJ, and approved August 15, 2018 (received for review March 11, 2018)
Footnotes
- ↵1To whom correspondence should be addressed. Email: dicarlo{at}ucla.edu.
Author contributions: M.D. and D.D.C. designed research; M.D. and J.N.L. performed research; T.W., S.M.D., and M.B.R. contributed new reagents/analytic tools; M.D. and J.N.L. analyzed data; and M.D. and D.D.C. wrote the paper.
Conflict of interest statement: The Regents of the University of California have filed a patent for the integrated vortex capture and droplet generator device of which D.D.C. and M.D. are inventors.
This article is a PNAS Direct Submission.
This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1803884115/-/DCSupplemental.
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Functional profiling of circulating tumor cells with an integrated vortex capture and single-cell protease activity assay
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- Applied Biological Sciences
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- Engineering
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