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Table of Contents
October 09, 2018; vol. 115 no. 41
This Week in PNAS
Letters (Online Only)
- You have accessAccurate timetrees require accurate calibrationsS. Blair Hedges, Qiqing Tao, Mark Walker, and Sudhir KumarPNAS October 9, 2018 115 (41) E9510-E9511; first published September 28, 2018. https://doi.org/10.1073/pnas.1812558115
- You have accessReply to Hedges et al.: Accurate timetrees do indeed require accurate calibrationsJennifer L. Morris, Mark N. Puttick, James W. Clark, Dianne Edwards, Paul Kenrick, Silvia Pressel, Charles H. Wellman, Ziheng Yang, Harald Schneider, and Philip C. J. DonoghuePNAS October 9, 2018 115 (41) E9512-E9513; first published September 28, 2018. https://doi.org/10.1073/pnas.1812816115
See companion article:
- Timescale of early land plant evolution- Feb 20, 2018
Inner Workings
An over-the-shoulder look at scientists at work.
- You have accessInner Workings: The mysterious parentage of the coveted black truffle
- Front Matter
Amber Dance
Profile
- You have accessProfile of Jonathan D. G. JonesJennifer ViegasPNAS October 9, 2018 115 (41) 10191-10194; first published September 24, 2018. https://doi.org/10.1073/pnas.1815072115
See companion article:
PNAS Plus Significance Statements
Brief statements written by the authors about the significance of their papers.
Perspective
- You have accessIdentity and novelty in the avian syrinxEvan P. Kingsley, Chad M. Eliason, Tobias Riede, Zhiheng Li, Tom W. Hiscock, Michael Farnsworth, Scott L. Thomson, Franz Goller, Clifford J. Tabin, and Julia A. ClarkePNAS October 9, 2018 115 (41) 10209-10217; first published September 24, 2018. https://doi.org/10.1073/pnas.1804586115
Physical Sciences
Applied Mathematics
- You have accessSymmetric coalescence of two hydraulic fracturesNiall J. O’Keeffe, Zhong Zheng, Herbert E. Huppert, and P. F. LindenPNAS October 9, 2018 115 (41) 10228-10232; first published September 25, 2018. https://doi.org/10.1073/pnas.1809233115
Applied Physical Sciences
- Open AccessStable Frank–Kasper phases of self-assembled, soft matter spheresAbhiram Reddy, Michael B. Buckley, Akash Arora, Frank S. Bates, Kevin D. Dorfman, and Gregory M. GrasonPNAS October 9, 2018 115 (41) 10233-10238; first published September 24, 2018. https://doi.org/10.1073/pnas.1809655115
- You have accessCrimping-induced structural gradients explain the lasting strength of poly l-lactide bioresorbable vascular scaffolds during hydrolysisKarthik Ramachandran, Tiziana Di Luccio, Artemis Ailianou, Mary Beth Kossuth, James P. Oberhauser, and Julia A. KornfieldPNAS October 9, 2018 115 (41) 10239-10244; first published September 17, 2018. https://doi.org/10.1073/pnas.1807347115
Biophysics and Computational Biology
- Open AccessParallel reaction pathways and noncovalent intermediates in thymidylate synthase revealed by experimental and computational toolsSvetlana A. Kholodar, Ananda K. Ghosh, Katarzyna Świderek, Vicent Moliner, and Amnon KohenPNAS October 9, 2018 115 (41) 10311-10314; first published September 24, 2018. https://doi.org/10.1073/pnas.1811059115
Chemistry
- Open AccessPhevamine A, a small molecule that suppresses plant immune responsesErinn M. O’Neill, Tatiana S. Mucyn, Jon B. Patteson, Omri M. Finkel, Eui-Hwan Chung, Joshua A. Baccile, Elisabetta Massolo, Frank C. Schroeder, Jeffery L. Dangl, and Bo LiPNAS October 9, 2018 115 (41) E9514-E9522; first published September 20, 2018. https://doi.org/10.1073/pnas.1803779115
- Open AccessEnergy-dependent quenching adjusts the excitation diffusion length to regulate photosynthetic light harvestingDoran I. G. Bennett, Graham R. Fleming, and Kapil AmarnathPNAS October 9, 2018 115 (41) E9523-E9531; first published September 20, 2018. https://doi.org/10.1073/pnas.1806597115
- Open AccessSAR by kinetics for drug discovery in protein misfolding diseasesSean Chia, Johnny Habchi, Thomas C. T. Michaels, Samuel I. A. Cohen, Sara Linse, Christopher M. Dobson, Tuomas P. J. Knowles, and Michele VendruscoloPNAS October 9, 2018 115 (41) 10245-10250; first published September 26, 2018. https://doi.org/10.1073/pnas.1807884115
- You have accessPredicting polymorphism in molecular crystals using orientational entropyPablo M. Piaggi and Michele ParrinelloPNAS October 9, 2018 115 (41) 10251-10256; first published September 20, 2018. https://doi.org/10.1073/pnas.1811056115
- You have accessRevised M06 density functional for main-group and transition-metal chemistryYing Wang, Pragya Verma, Xinsheng Jin, Donald G. Truhlar, and Xiao HePNAS October 9, 2018 115 (41) 10257-10262; first published September 20, 2018. https://doi.org/10.1073/pnas.1810421115
- You have accessTwo-dimensional dry ices with rich polymorphic and polyamorphic phase behaviorJaeil Bai, Joseph S. Francisco, and Xiao Cheng ZengPNAS October 9, 2018 115 (41) 10263-10268; first published September 24, 2018. https://doi.org/10.1073/pnas.1809198115
- You have accessMultiscale wavelet decomposition of time-resolved X-ray diffraction signals in cyclohexadieneVladimir Al. Osipov, Markus Kowalewski, and Shaul MukamelPNAS October 9, 2018 115 (41) 10269-10274; first published September 25, 2018. https://doi.org/10.1073/pnas.1811983115
- You have accessInterferometric plasmonic imaging and detection of single exosomesYuting Yang, Guangxia Shen, Hui Wang, Hongxia Li, Ting Zhang, Nongjian Tao, Xianting Ding, and Hui YuPNAS October 9, 2018 115 (41) 10275-10280; first published September 24, 2018. https://doi.org/10.1073/pnas.1804548115
Earth, Atmospheric, and Planetary Sciences
- Open AccessUse of scenario ensembles for deriving seismic riskTom R. Robinson, Nicholas J. Rosser, Alexander L. Densmore, Katie J. Oven, Surya N. Shrestha, and Ramesh GuragainPNAS October 9, 2018 115 (41) E9532-E9541; first published September 24, 2018. https://doi.org/10.1073/pnas.1807433115
- You have accessSediment starvation destroys New York City marshes’ resistance to sea level riseDorothy M. Peteet, Jonathan Nichols, Timothy Kenna, Clara Chang, James Browne, Mohammad Reza, Stephen Kovari, Louisa Liberman, and Stephanie Stern-ProtzPNAS October 9, 2018 115 (41) 10281-10286; first published September 24, 2018. https://doi.org/10.1073/pnas.1715392115
- You have accessOrigin and significance of Si and O isotope heterogeneities in Phanerozoic, Archean, and Hadean zirconDustin Trail, Patrick Boehnke, Paul S. Savage, Ming-Chang Liu, Martha L. Miller, and Ilya BindemanPNAS October 9, 2018 115 (41) 10287-10292; first published September 24, 2018. https://doi.org/10.1073/pnas.1808335115
- You have accessEarth’s outgoing longwave radiation linear due to H2O greenhouse effectDaniel D. B. Koll and Timothy W. CroninPNAS October 9, 2018 115 (41) 10293-10298; first published September 25, 2018. https://doi.org/10.1073/pnas.1809868115
Engineering
- You have accessConductively coupled flexible silicon electronic systems for chronic neural electrophysiology
- From the Cover
Jinghua Li, Enming Song, Chia-Han Chiang, Ki Jun Yu, Jahyun Koo, Haina Du, Yishan Zhong, Mackenna Hill, Charles Wang, Jize Zhang, Yisong Chen, Limei Tian, Yiding Zhong, Guanhua Fang, Jonathan Viventi, and John A. RogersPNAS October 9, 2018 115 (41) E9542-E9549; first published September 18, 2018. https://doi.org/10.1073/pnas.1813187115
Mathematics
- Open AccessMechanics of mouse blastocyst hatching revealed by a hydrogel-based microdeformation assayKarolis Leonavicius, Christophe Royer, Chris Preece, Benjamin Davies, John S. Biggins, and Shankar SrinivasPNAS October 9, 2018 115 (41) 10375-10380; first published September 19, 2018. https://doi.org/10.1073/pnas.1719930115
Statistics
- Open AccessGeneralized least squares can overcome the critical threshold in respondent-driven samplingSebastien Roch and Karl RohePNAS October 9, 2018 115 (41) 10299-10304; first published September 25, 2018. https://doi.org/10.1073/pnas.1706699115
Social Sciences
Psychological and Cognitive Sciences
- You have accessNeural basis of location-specific pupil luminance modulationChin-An Wang and Douglas P. MunozPNAS October 9, 2018 115 (41) 10446-10451; first published September 24, 2018. https://doi.org/10.1073/pnas.1809668115
- Open AccessMovement kinematics drive chain selection toward intention detectionMarco Soriano, Andrea Cavallo, Alessandro D’Ausilio, Cristina Becchio, and Luciano FadigaPNAS October 9, 2018 115 (41) 10452-10457; first published September 21, 2018. https://doi.org/10.1073/pnas.1809825115
Social Sciences
- Open AccessGeneralized least squares can overcome the critical threshold in respondent-driven samplingSebastien Roch and Karl RohePNAS October 9, 2018 115 (41) 10299-10304; first published September 25, 2018. https://doi.org/10.1073/pnas.1706699115
Biological Sciences
Applied Biological Sciences
- Open AccessGlyphosate perturbs the gut microbiota of honey beesErick V. S. Motta, Kasie Raymann, and Nancy A. MoranPNAS October 9, 2018 115 (41) 10305-10310; first published September 24, 2018. https://doi.org/10.1073/pnas.1803880115
Biochemistry
- You have accessZFAND5/ZNF216 is an activator of the 26S proteasome that stimulates overall protein degradationDonghoon Lee, Shinichi Takayama, and Alfred L. GoldbergPNAS October 9, 2018 115 (41) E9550-E9559; first published September 25, 2018. https://doi.org/10.1073/pnas.1809934115
- Open AccessATP hydrolysis-coupled peptide translocation mechanism of Mycobacterium tuberculosis ClpBHongjun Yu, Tania J. Lupoli, Amanda Kovach, Xing Meng, Gongpu Zhao, Carl F. Nathan, and Huilin LiPNAS October 9, 2018 115 (41) E9560-E9569; first published September 26, 2018. https://doi.org/10.1073/pnas.1810648115
- Open AccessParallel reaction pathways and noncovalent intermediates in thymidylate synthase revealed by experimental and computational toolsSvetlana A. Kholodar, Ananda K. Ghosh, Katarzyna Świderek, Vicent Moliner, and Amnon KohenPNAS October 9, 2018 115 (41) 10311-10314; first published September 24, 2018. https://doi.org/10.1073/pnas.1811059115
- Open AccessSingle-stranded telomere-binding protein employs a dual rheostat for binding affinity and specificity that drives functionLeslie W. Glustrom, Kenneth R. Lyon, Margherita Paschini, Cynthia M. Reyes, Nicholas V. Parsonnet, Tasha B. Toro, Victoria Lundblad, and Deborah S. WuttkePNAS October 9, 2018 115 (41) 10315-10320; first published September 24, 2018. https://doi.org/10.1073/pnas.1722147115
Biophysics and Computational Biology
- Open AccessSAR by kinetics for drug discovery in protein misfolding diseasesSean Chia, Johnny Habchi, Thomas C. T. Michaels, Samuel I. A. Cohen, Sara Linse, Christopher M. Dobson, Tuomas P. J. Knowles, and Michele VendruscoloPNAS October 9, 2018 115 (41) 10245-10250; first published September 26, 2018. https://doi.org/10.1073/pnas.1807884115
- You have accessOn the control of the proton current in the voltage-gated proton channel Hv1Myungjin Lee, Chen Bai, Mikolaj Feliks, Raphael Alhadeff, and Arieh WarshelPNAS October 9, 2018 115 (41) 10321-10326; first published September 25, 2018. https://doi.org/10.1073/pnas.1809766115
- You have accessExploring the free-energy landscape of GPCR activationRaphael Alhadeff, Igor Vorobyov, Han Wool Yoon, and Arieh WarshelPNAS October 9, 2018 115 (41) 10327-10332; first published September 26, 2018. https://doi.org/10.1073/pnas.1810316115
- You have accessStructural titration of receptor ion channel GLIC gating by HS-AFM
- From the Cover
Yi Ruan, Kevin Kao, Solène Lefebvre, Arin Marchesi, Pierre-Jean Corringer, Richard K. Hite, and Simon ScheuringPNAS October 9, 2018 115 (41) 10333-10338; first published September 4, 2018. https://doi.org/10.1073/pnas.1805621115See companion article:
- You have accessThe interaction of talin with the cell membrane is essential for integrin activation and focal adhesion formationKrishna Chinthalapudi, Erumbi S. Rangarajan, and Tina IzardPNAS October 9, 2018 115 (41) 10339-10344; first published September 25, 2018. https://doi.org/10.1073/pnas.1806275115
- Open AccessStructural evidence for the roles of divalent cations in actin polymerization and activation of ATP hydrolysisClement P. M. Scipion, Umesh Ghoshdastider, Fernando J. Ferrer, Tsz-Ying Yuen, Jantana Wongsantichon, and Robert C. RobinsonPNAS October 9, 2018 115 (41) 10345-10350; first published September 25, 2018. https://doi.org/10.1073/pnas.1806394115
Cell Biology
- You have accessRole for ERK1/2-dependent activation of FCHSD2 in cancer cell-selective regulation of clathrin-mediated endocytosisGuan-Yu Xiao, Aparna Mohanakrishnan, and Sandra L. SchmidPNAS October 9, 2018 115 (41) E9570-E9579; first published September 24, 2018. https://doi.org/10.1073/pnas.1810209115
- You have accessERβ-mediated induction of cystatins results in suppression of TGFβ signaling and inhibition of triple-negative breast cancer metastasisJordan M. Reese, Elizabeth S. Bruinsma, Adam W. Nelson, Igor Chernukhin, Jason S. Carroll, Ying Li, Malayannan Subramaniam, Vera J. Suman, Vivian Negron, David G. Monroe, James N. Ingle, Matthew P. Goetz, and John R. HawsePNAS October 9, 2018 115 (41) E9580-E9589; first published September 26, 2018. https://doi.org/10.1073/pnas.1807751115
- Open AccessMechanism of drug extrusion by brain endothelial cells via lysosomal drug trapping and disposal by neutrophilsAndreas Noack, Birthe Gericke, Maren von Köckritz-Blickwede, Arne Menze, Sandra Noack, Ingo Gerhauser, Felix Osten, Hassan Y. Naim, and Wolfgang LöscherPNAS October 9, 2018 115 (41) E9590-E9599; first published September 25, 2018. https://doi.org/10.1073/pnas.1719642115
- Open AccessBRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activationAndrew G. Li, Elizabeth C. Murphy, Aedin C. Culhane, Emily Powell, Hua Wang, Roderick T. Bronson, Thanh Von, Anita Giobbie-Hurder, Rebecca S. Gelman, Kimberly J. Briggs, Helen Piwnica-Worms, Jean J. Zhao, Andrew L. Kung, William G. Kaelin Jr., and David M. LivingstonPNAS October 9, 2018 115 (41) E9600-E9609; first published September 25, 2018. https://doi.org/10.1073/pnas.1807112115
- You have accessVEGF-B is a potent antioxidantPachiappan Arjunan, Xianchai Lin, Zhongshu Tang, Yuxiang Du, Anil Kumar, Lixian Liu, Xiangke Yin, Lijuan Huang, Wei Chen, Qishan Chen, Zhimin Ye, Shasha Wang, Haiqing Kuang, Linbin Zhou, Kai Xu, Xue Chen, Haitao Zeng, Weisi Lu, Yihai Cao, Yizhi Liu, Chen Zhao, and Xuri LiPNAS October 9, 2018 115 (41) 10351-10356; first published September 24, 2018. https://doi.org/10.1073/pnas.1801379115
- You have accessPAX5-ELN oncoprotein promotes multistep B-cell acute lymphoblastic leukemia in miceLaura Jamrog, Guillaume Chemin, Vincent Fregona, Lucie Coster, Marlène Pasquet, Chloé Oudinet, Nelly Rouquié, Naïs Prade, Stéphanie Lagarde, Charlotte Cresson, Sylvie Hébrard, Ngoc Sa Nguyen Huu, Marina Bousquet, Cathy Quelen, Pierre Brousset, Stéphane J. C. Mancini, Eric Delabesse, Ahmed Amine Khamlichi, Bastien Gerby, and Cyril BroccardoPNAS October 9, 2018 115 (41) 10357-10362; first published September 26, 2018. https://doi.org/10.1073/pnas.1721678115
- You have accessThe Atg2-Atg18 complex tethers pre-autophagosomal membranes to the endoplasmic reticulum for autophagosome formationTetsuya Kotani, Hiromi Kirisako, Michiko Koizumi, Yoshinori Ohsumi, and Hitoshi NakatogawaPNAS October 9, 2018 115 (41) 10363-10368; first published September 25, 2018. https://doi.org/10.1073/pnas.1806727115
- Open AccessNebulin stiffens the thin filament and augments cross-bridge interaction in skeletal muscleBalázs Kiss, Eun-Jeong Lee, Weikang Ma, Frank W. Li, Paola Tonino, Srboljub M. Mijailovich, Thomas C. Irving, and Henk L. GranzierPNAS October 9, 2018 115 (41) 10369-10374; first published September 24, 2018. https://doi.org/10.1073/pnas.1804726115
Developmental Biology
- Open AccessMechanics of mouse blastocyst hatching revealed by a hydrogel-based microdeformation assayKarolis Leonavicius, Christophe Royer, Chris Preece, Benjamin Davies, John S. Biggins, and Shankar SrinivasPNAS October 9, 2018 115 (41) 10375-10380; first published September 19, 2018. https://doi.org/10.1073/pnas.1719930115
- Open AccessCorepressor SMRT is required to maintain Hox transcriptional memory during somitogenesisSuk-Hyun Hong, Sungsoon Fang, Benson C. Lu, Russell Nofsinger, Yasuhiko Kawakami, Glenda L. Castro, Yunqiang Yin, Chengqi Lin, Ruth T. Yu, Michael Downes, Juan Carlos Izpisúa Belmonte, Ali Shilatifard, and Ronald M. EvansPNAS October 9, 2018 115 (41) 10381-10386; first published September 25, 2018. https://doi.org/10.1073/pnas.1809480115
- You have accessRole of transcription complexes in the formation of the basal methylation pattern in early developmentRazi Greenfield, Amalia Tabib, Ilana Keshet, Joshua Moss, Ofra Sabag, Alon Goren, and Howard CedarPNAS October 9, 2018 115 (41) 10387-10391; first published September 26, 2018. https://doi.org/10.1073/pnas.1804755115
Ecology
- You have accessSediment starvation destroys New York City marshes’ resistance to sea level riseDorothy M. Peteet, Jonathan Nichols, Timothy Kenna, Clara Chang, James Browne, Mohammad Reza, Stephen Kovari, Louisa Liberman, and Stephanie Stern-ProtzPNAS October 9, 2018 115 (41) 10281-10286; first published September 24, 2018. https://doi.org/10.1073/pnas.1715392115
- You have accessContrasting dynamics and trait controls in first-order root compared with leaf litter decompositionTao Sun, Sarah E. Hobbie, Björn Berg, Hongguang Zhang, Qingkui Wang, Zhengwen Wang, and Stephan HättenschwilerPNAS October 9, 2018 115 (41) 10392-10397; first published September 25, 2018. https://doi.org/10.1073/pnas.1716595115
Evolution
- You have accessVersatility of multivalent orientation, inverted meiosis, and rescued fitness in holocentric chromosomal hybrids
- From the Cover
Vladimir A. Lukhtanov, Vlad Dincă, Magne Friberg, Jindra Šíchová, Martin Olofsson, Roger Vila, František Marec, and Christer WiklundPNAS October 9, 2018 115 (41) E9610-E9619; first published September 28, 2018. https://doi.org/10.1073/pnas.1802610115 - You have accessGenomic responses to selection for tame/aggressive behaviors in the silver fox (Vulpes vulpes)Xu Wang, Lenore Pipes, Lyudmila N. Trut, Yury Herbeck, Anastasiya V. Vladimirova, Rimma G. Gulevich, Anastasiya V. Kharlamova, Jennifer L. Johnson, Gregory M. Acland, Anna V. Kukekova, and Andrew G. ClarkPNAS October 9, 2018 115 (41) 10398-10403; first published September 18, 2018. https://doi.org/10.1073/pnas.1800889115
Genetics
- Open AccessMutations of mitochondrial DNA are not major contributors to aging of fruit fliesTimo E. S. Kauppila, Ana Bratic, Martin Borch Jensen, Francesca Baggio, Linda Partridge, Heinrich Jasper, Sebastian Grönke, and Nils-Göran LarssonPNAS October 9, 2018 115 (41) E9620-E9629; first published September 24, 2018. https://doi.org/10.1073/pnas.1721683115
Immunology and Inflammation
- Open AccessCochaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and β1-integrin functionVirginia Andreani, Senthilkumar Ramamoorthy, Abhinav Pandey, Ekaterina Lupar, Stephen L. Nutt, Tim Lämmermann, and Rudolf GrosschedlPNAS October 9, 2018 115 (41) E9630-E9639; first published September 26, 2018. https://doi.org/10.1073/pnas.1809739115
- You have accessMAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotypeEmilie Plantamura, Amiran Dzutsev, Mathias Chamaillard, Sophia Djebali, Lyvia Moudombi, Lilia Boucinha, Morgan Grau, Claire Macari, David Bauché, Oana Dumitrescu, Jean-Philippe Rasigade, Saskia Lippens, Michelina Plateroti, Elsa Kress, Annabelle Cesaro, Clovis Bondu, Ulrike Rothermel, Mathias Heikenwälder, Gerard Lina, Azzak Bentaher-Belaaouaj, Julien C. Marie, Christophe Caux, Giorgio Trinchieri, Jacqueline Marvel, and Marie-Cecile MichalletPNAS October 9, 2018 115 (41) 10404-10409; first published September 24, 2018. https://doi.org/10.1073/pnas.1722372115
- You have accessSiglec-7 engagement by GBS β-protein suppresses pyroptotic cell death of natural killer cellsJerry J. Fong, Chih-Ming Tsai, Sudeshna Saha, Victor Nizet, Ajit Varki, and Jack D. BuiPNAS October 9, 2018 115 (41) 10410-10415; first published September 25, 2018. https://doi.org/10.1073/pnas.1804108115
- You have accessOptimal protection against Salmonella infection requires noncirculating memoryJoseph M. Benoun, Newton G. Peres, Nancy Wang, Oanh H. Pham, Victoria L. Rudisill, Zachary N. Fogassy, Paul G. Whitney, Daniel Fernandez-Ruiz, Thomas Gebhardt, Quynh-Mai Pham, Lynn Puddington, Sammy Bedoui, Richard A. Strugnell, and Stephen J. McSorleyPNAS October 9, 2018 115 (41) 10416-10421; first published September 25, 2018. https://doi.org/10.1073/pnas.1808339115
Medical Sciences
- You have accessHypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichmentJie Lan, Haiquan Lu, Debangshu Samanta, Shaima Salman, You Lu, and Gregg L. SemenzaPNAS October 9, 2018 115 (41) E9640-E9648; first published September 21, 2018. https://doi.org/10.1073/pnas.1809695115
Microbiology
- Open AccessPhevamine A, a small molecule that suppresses plant immune responsesErinn M. O’Neill, Tatiana S. Mucyn, Jon B. Patteson, Omri M. Finkel, Eui-Hwan Chung, Joshua A. Baccile, Elisabetta Massolo, Frank C. Schroeder, Jeffery L. Dangl, and Bo LiPNAS October 9, 2018 115 (41) E9514-E9522; first published September 20, 2018. https://doi.org/10.1073/pnas.1803779115
- You have accessCommercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infectionsMario D. Garcia, Sheena M. H. Chua, Yu-Shang Low, Yu-Ting Lee, Kylie Agnew-Francis, Jian-Guo Wang, Amanda Nouwens, Thierry Lonhienne, Craig M. Williams, James A. Fraser, and Luke W. GuddatPNAS October 9, 2018 115 (41) E9649-E9658; first published September 24, 2018. https://doi.org/10.1073/pnas.1809422115
- You have accessIL-15 regulates susceptibility of CD4+ T cells to HIV infectionLara Manganaro, Patrick Hong, Matthew M. Hernandez, Dionne Argyle, Lubbertus C. F. Mulder, Uma Potla, Felipe Diaz-Griffero, Benhur Lee, Ana Fernandez-Sesma, and Viviana SimonPNAS October 9, 2018 115 (41) E9659-E9667; first published September 26, 2018. https://doi.org/10.1073/pnas.1806695115
- Open AccessGenomic blueprint of a relapsing fever pathogen in 15th century ScandinaviaMeriam Guellil, Oliver Kersten, Amine Namouchi, Egil L. Bauer, Michael Derrick, Anne Ø. Jensen, Nils C. Stenseth, and Barbara BramantiPNAS October 9, 2018 115 (41) 10422-10427; first published September 24, 2018. https://doi.org/10.1073/pnas.1807266115
- Open AccessComparative immunogenicity and efficacy of equivalent outer membrane vesicle and glycoconjugate vaccines against nontyphoidal SalmonellaFrancesca Micoli, Simona Rondini, Renzo Alfini, Luisa Lanzilao, Francesca Necchi, Aurel Negrea, Omar Rossi, Cornelia Brandt, Simon Clare, Pietro Mastroeni, Rino Rappuoli, Allan Saul, and Calman A. MacLennanPNAS October 9, 2018 115 (41) 10428-10433; first published September 27, 2018. https://doi.org/10.1073/pnas.1807655115
- You have accessHuman Endogenous Retrovirus-K HML-2 integration within RASGRF2 is associated with intravenous drug abuse and modulates transcription in a cell-line modelTimokratis Karamitros, Tara Hurst, Emanuele Marchi, Eirini Karamichali, Urania Georgopoulou, Andreas Mentis, Joey Riepsaame, Audrey Lin, Dimitrios Paraskevis, Angelos Hatzakis, John McLauchlan, Aris Katzourakis, and Gkikas MagiorkinisPNAS October 9, 2018 115 (41) 10434-10439; first published September 24, 2018. https://doi.org/10.1073/pnas.1811940115
- Open AccessTRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination
- From the Cover
Maria Bottermann, Stian Foss, Laurens M. van Tienen, Marina Vaysburd, James Cruickshank, Kevin O’Connell, Jessica Clark, Keith Mayes, Katie Higginson, Jack C. Hirst, Martin B. McAdam, Greg Slodkowicz, Edward Hutchinson, Patrycja Kozik, Jan Terje Andersen, and Leo C. JamesPNAS October 9, 2018 115 (41) 10440-10445; first published September 12, 2018. https://doi.org/10.1073/pnas.1806314115See companion article:
Neuroscience
- You have accessLet-7i inhibition enhances progesterone-induced functional recovery in a mouse model of ischemiaTrinh Nguyen, Chang Su, and Meharvan SinghPNAS October 9, 2018 115 (41) E9668-E9677; first published September 20, 2018. https://doi.org/10.1073/pnas.1803384115
- You have accessFUS interacts with ATP synthase beta subunit and induces mitochondrial unfolded protein response in cellular and animal modelsJianwen Deng, Peng Wang, Xiaoping Chen, Haipeng Cheng, Jianghong Liu, Kazuo Fushimi, Li Zhu, and Jane Y. WuPNAS October 9, 2018 115 (41) E9678-E9686; first published September 24, 2018. https://doi.org/10.1073/pnas.1806655115
- You have accessBlood-derived plasminogen drives brain inflammation and plaque deposition in a mouse model of Alzheimer’s diseaseSarah K. Baker, Zu-Lin Chen, Erin H. Norris, Alexey S. Revenko, A. Robert MacLeod, and Sidney StricklandPNAS October 9, 2018 115 (41) E9687-E9696; first published September 25, 2018. https://doi.org/10.1073/pnas.1811172115
- Open AccessSingle-molecule analysis of endogenous β-actin mRNA trafficking reveals a mechanism for compartmentalized mRNA localization in axonsBenita Turner-Bridger, Maximillian Jakobs, Leila Muresan, Hovy Ho-Wai Wong, Kristian Franze, William A. Harris, and Christine E. HoltPNAS October 9, 2018 115 (41) E9697-E9706; first published September 25, 2018. https://doi.org/10.1073/pnas.1806189115
- You have accessActivation of autophagy rescues synaptic and cognitive deficits in fragile X miceJingqi Yan, Morgan W. Porch, Brenda Court-Vazquez, Michael V. L. Bennett, and R. Suzanne ZukinPNAS October 9, 2018 115 (41) E9707-E9716; first published September 21, 2018. https://doi.org/10.1073/pnas.1808247115
- Open AccessASTN2 modulates synaptic strength by trafficking and degradation of surface proteinsHourinaz Behesti, Taylor R. Fore, Peter Wu, Zachi Horn, Mary Leppert, Court Hull, and Mary E. HattenPNAS October 9, 2018 115 (41) E9717-E9726; first published September 21, 2018. https://doi.org/10.1073/pnas.1809382115
- Open AccessGenetically defined cellular correlates of the baseline brain MRI signalJie Wen, Manu S. Goyal, Serguei V. Astafiev, Marcus E. Raichle, and Dmitriy A. YablonskiyPNAS October 9, 2018 115 (41) E9727-E9736; first published September 25, 2018. https://doi.org/10.1073/pnas.1808121115
- You have accessNeural basis of location-specific pupil luminance modulationChin-An Wang and Douglas P. MunozPNAS October 9, 2018 115 (41) 10446-10451; first published September 24, 2018. https://doi.org/10.1073/pnas.1809668115
- Open AccessMovement kinematics drive chain selection toward intention detectionMarco Soriano, Andrea Cavallo, Alessandro D’Ausilio, Cristina Becchio, and Luciano FadigaPNAS October 9, 2018 115 (41) 10452-10457; first published September 21, 2018. https://doi.org/10.1073/pnas.1809825115
- You have accessA single phosphorylation site of SIK3 regulates daily sleep amounts and sleep need in miceTakato Honda, Tomoyuki Fujiyama, Chika Miyoshi, Aya Ikkyu, Noriko Hotta-Hirashima, Satomi Kanno, Seiya Mizuno, Fumihiro Sugiyama, Satoru Takahashi, Hiromasa Funato, and Masashi YanagisawaPNAS October 9, 2018 115 (41) 10458-10463; first published September 25, 2018. https://doi.org/10.1073/pnas.1810823115
- You have accessAxonal plasticity associated with perceptual learning in adult macaque primary visual cortexTimo van Kerkoerle, Sally A. Marik, Stephan Meyer zum Alten Borgloh, and Charles D. GilbertPNAS October 9, 2018 115 (41) 10464-10469; first published September 27, 2018. https://doi.org/10.1073/pnas.1812932115
- You have accessDesert ants possess distinct memories for food and nest odorsRoman Huber and Markus KnadenPNAS October 9, 2018 115 (41) 10470-10474; first published September 24, 2018. https://doi.org/10.1073/pnas.1809433115
- You have accessStimulation of AMPK prevents degeneration of photoreceptors and the retinal pigment epitheliumLei Xu, Li Kong, Jiangang Wang, and John D. AshPNAS October 9, 2018 115 (41) 10475-10480; first published September 24, 2018. https://doi.org/10.1073/pnas.1802724115
- You have accessSmall molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neuronsJordi Pujols, Samuel Peña-Díaz, Diana F. Lázaro, Francesca Peccati, Francisca Pinheiro, Danilo González, Anita Carija, Susanna Navarro, María Conde-Giménez, Jesús García, Salvador Guardiola, Ernest Giralt, Xavier Salvatella, Javier Sancho, Mariona Sodupe, Tiago Fleming Outeiro, Esther Dalfó, and Salvador VenturaPNAS October 9, 2018 115 (41) 10481-10486; first published September 24, 2018. https://doi.org/10.1073/pnas.1804198115
- You have accessRapid stimulation of human dentate gyrus function with acute mild exerciseKazuya Suwabe, Kyeongho Byun, Kazuki Hyodo, Zachariah M. Reagh, Jared M. Roberts, Akira Matsushita, Kousaku Saotome, Genta Ochi, Takemune Fukuie, Kenji Suzuki, Yoshiyuki Sankai, Michael A. Yassa, and Hideaki SoyaPNAS October 9, 2018 115 (41) 10487-10492; first published September 24, 2018. https://doi.org/10.1073/pnas.1805668115
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- You have accessStriatal dopamine 2 receptor upregulation during development predisposes to diet-induced obesity by reducing energy output in miceMarie A. Labouesse, Andrea M. Sartori, Oliver Weinmann, Eleanor H. Simpson, Christoph Kellendonk, and Ulrike Weber-StadlbauerPNAS October 9, 2018 115 (41) 10493-10498; first published September 25, 2018. https://doi.org/10.1073/pnas.1800171115
- Open AccessBottom-up saliency and top-down learning in the primary visual cortex of monkeysYin Yan, Li Zhaoping, and Wu LiPNAS October 9, 2018 115 (41) 10499-10504; first published September 25, 2018. https://doi.org/10.1073/pnas.1803854115
- Open AccessFunctionally specific optogenetic modulation in primate visual cortexMykyta M. Chernov, Robert M. Friedman, Gang Chen, Gene R. Stoner, and Anna Wang RoePNAS October 9, 2018 115 (41) 10505-10510; first published September 26, 2018. https://doi.org/10.1073/pnas.1802018115
Pharmacology
- You have accessl-Serine–modified polyamidoamine dendrimer as a highly potent renal targeting drug carrierSatoru Matsuura, Hidemasa Katsumi, Hiroe Suzuki, Natsuko Hirai, Hidetaka Hayashi, Kazuhiro Koshino, Takahiro Higuchi, Yusuke Yagi, Hiroyuki Kimura, Toshiyasu Sakane, and Akira YamamotoPNAS October 9, 2018 115 (41) 10511-10516; first published September 24, 2018. https://doi.org/10.1073/pnas.1808168115
Physiology
- You have accessCold exposure causes cell death by depolarization-mediated Ca2+ overload in a chill-susceptible insectJeppe Seamus Bayley, Christian Bak Winther, Mads Kuhlmann Andersen, Camilla Grønkjær, Ole Bækgaard Nielsen, Thomas Holm Pedersen, and Johannes OvergaardPNAS October 9, 2018 115 (41) E9737-E9744; first published September 25, 2018. https://doi.org/10.1073/pnas.1813532115
- Open AccessNanoscale remodeling of ryanodine receptor cluster size underlies cerebral microvascular dysfunction in Duchenne muscular dystrophy
- From the Cover
Harry A. T. Pritchard, Paulo W. Pires, Evan Yamasaki, Pratish Thakore, and Scott EarleyPNAS October 9, 2018 115 (41) E9745-E9752; first published September 4, 2018. https://doi.org/10.1073/pnas.1804593115See companion article:
Plant Biology
- Open AccessEnergy-dependent quenching adjusts the excitation diffusion length to regulate photosynthetic light harvestingDoran I. G. Bennett, Graham R. Fleming, and Kapil AmarnathPNAS October 9, 2018 115 (41) E9523-E9531; first published September 20, 2018. https://doi.org/10.1073/pnas.1806597115
- Open AccessDistinct modes of derepression of an Arabidopsis immune receptor complex by two different bacterial effectors
- Inaugural Article
Yan Ma, Hailong Guo, Lanxi Hu, Paula Pons Martinez, Panagiotis N. Moschou, Volkan Cevik, Pingtao Ding, Zane Duxbury, Panagiotis F. Sarris, and Jonathan D. G. JonesPNAS October 9, 2018 115 (41) 10218-10227; first published September 25, 2018. https://doi.org/10.1073/pnas.1811858115See companion article:
- Profile of Jonathan D. G. Jones- Sep 24, 2018
- You have accessStructure of a PSI–LHCI–cyt b6f supercomplex in Chlamydomonas reinhardtii promoting cyclic electron flow under anaerobic conditionsJanina Steinbeck, Ian L. Ross, Rosalba Rothnagel, Philipp Gäbelein, Stefan Schulze, Nichole Giles, Rubbiya Ali, Rohan Drysdale, Emma Sierecki, Yann Gambin, Henning Stahlberg, Yuichiro Takahashi, Michael Hippler, and Ben HankamerPNAS October 9, 2018 115 (41) 10517-10522; first published September 25, 2018. https://doi.org/10.1073/pnas.1809973115
- You have accessDawn and photoperiod sensing by phytochrome ADaniel D. Seaton, Gabriela Toledo-Ortiz, Ashwin Ganpudi, Akane Kubota, Takato Imaizumi, and Karen J. HallidayPNAS October 9, 2018 115 (41) 10523-10528; first published September 25, 2018. https://doi.org/10.1073/pnas.1803398115
Correction (Online Only)
- You have accessCorrection for Mittal et al., Codon usage influences fitness through RNA toxicityPNAS October 9, 2018 115 (41) E9753; first published October 1, 2018. https://doi.org/10.1073/pnas.1815812115
SI Correction (Online Only)
- You have accessCorrection to Supporting Information for Reid-Bayliss and Loeb, Accurate RNA consensus sequencing for high-fidelity detection of transcriptional mutagenesis-induced epimutationsPNAS October 9, 2018 115 (41) E9754; first published October 1, 2018. https://doi.org/10.1073/pnas.1815350115
Commentaries
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