Skip to main content
  • Submit
  • About
    • Editorial Board
    • PNAS Staff
    • FAQ
    • Accessibility Statement
    • Rights and Permissions
    • Site Map
  • Contact
  • Journal Club
  • Subscribe
    • Subscription Rates
    • Subscriptions FAQ
    • Open Access
    • Recommend PNAS to Your Librarian
  • Log in
  • My Cart

Main menu

  • Home
  • Articles
    • Current
    • Special Feature Articles - Most Recent
    • Special Features
    • Colloquia
    • Collected Articles
    • PNAS Classics
    • List of Issues
  • Front Matter
  • News
    • For the Press
    • This Week In PNAS
    • PNAS in the News
  • Podcasts
  • Authors
    • Information for Authors
    • Editorial and Journal Policies
    • Submission Procedures
    • Fees and Licenses
  • Submit
  • About
    • Editorial Board
    • PNAS Staff
    • FAQ
    • Accessibility Statement
    • Rights and Permissions
    • Site Map
  • Contact
  • Journal Club
  • Subscribe
    • Subscription Rates
    • Subscriptions FAQ
    • Open Access
    • Recommend PNAS to Your Librarian

User menu

  • Log in
  • My Cart

Search

  • Advanced search
Home
Home

Advanced Search

  • Home
  • Articles
    • Current
    • Special Feature Articles - Most Recent
    • Special Features
    • Colloquia
    • Collected Articles
    • PNAS Classics
    • List of Issues
  • Front Matter
  • News
    • For the Press
    • This Week In PNAS
    • PNAS in the News
  • Podcasts
  • Authors
    • Information for Authors
    • Editorial and Journal Policies
    • Submission Procedures
    • Fees and Licenses

New Research In

Physical Sciences

Featured Portals

  • Physics
  • Chemistry
  • Sustainability Science

Articles by Topic

  • Applied Mathematics
  • Applied Physical Sciences
  • Astronomy
  • Computer Sciences
  • Earth, Atmospheric, and Planetary Sciences
  • Engineering
  • Environmental Sciences
  • Mathematics
  • Statistics

Social Sciences

Featured Portals

  • Anthropology
  • Sustainability Science

Articles by Topic

  • Economic Sciences
  • Environmental Sciences
  • Political Sciences
  • Psychological and Cognitive Sciences
  • Social Sciences

Biological Sciences

Featured Portals

  • Sustainability Science

Articles by Topic

  • Agricultural Sciences
  • Anthropology
  • Applied Biological Sciences
  • Biochemistry
  • Biophysics and Computational Biology
  • Cell Biology
  • Developmental Biology
  • Ecology
  • Environmental Sciences
  • Evolution
  • Genetics
  • Immunology and Inflammation
  • Medical Sciences
  • Microbiology
  • Neuroscience
  • Pharmacology
  • Physiology
  • Plant Biology
  • Population Biology
  • Psychological and Cognitive Sciences
  • Sustainability Science
  • Systems Biology

Table of Contents

October 09, 2018; vol. 115 no. 41

This Week in PNAS

  • You have access
    In This Issue
    PNAS October 9, 2018 115 (41) 10185-10187; https://doi.org/10.1073/iti4118115

Letters (Online Only)

  • You have access
    Accurate timetrees require accurate calibrations
    S. Blair Hedges, Qiqing Tao, Mark Walker, and Sudhir Kumar
    PNAS October 9, 2018 115 (41) E9510-E9511; first published September 28, 2018. https://doi.org/10.1073/pnas.1812558115
  • You have access
    Reply to Hedges et al.: Accurate timetrees do indeed require accurate calibrations
    Jennifer L. Morris, Mark N. Puttick, James W. Clark, Dianne Edwards, Paul Kenrick, Silvia Pressel, Charles H. Wellman, Ziheng Yang, Harald Schneider, and Philip C. J. Donoghue
    PNAS October 9, 2018 115 (41) E9512-E9513; first published September 28, 2018. https://doi.org/10.1073/pnas.1812816115

    See companion article:

    • Timescale of early land plant evolution
      - Feb 20, 2018

Inner Workings

An over-the-shoulder look at scientists at work.
  • You have access
    Inner Workings: The mysterious parentage of the coveted black truffle
    • Front Matter
    Amber Dance
    PNAS October 9, 2018 115 (41) 10188-10190; https://doi.org/10.1073/pnas.1814128115

Profile

  • You have access
    Profile of Jonathan D. G. Jones
    Jennifer Viegas
    PNAS October 9, 2018 115 (41) 10191-10194; first published September 24, 2018. https://doi.org/10.1073/pnas.1815072115

    See companion article:

    • Distinct modes of derepression of an Arabidopsis immune receptor complex by two different bacterial effectors
      - Sep 25, 2018

Commentaries

  • You have access
    Ryanodine receptor cluster size sets the tone in cerebral smooth muscle
    Christian Soeller
    PNAS October 9, 2018 115 (41) 10195-10197; first published September 26, 2018. https://doi.org/10.1073/pnas.1814207115

    See companion article:

    • Nanoscale remodeling of ryanodine receptor cluster size underlies cerebral microvascular dysfunction in Duchenne muscular dystrophy
      - Sep 04, 2018
  • You have access
    Direct visualization of ion-channel gating in a native environment
    Yvonne Gicheru and Sudha Chakrapani
    PNAS October 9, 2018 115 (41) 10198-10200; first published September 26, 2018. https://doi.org/10.1073/pnas.1814277115

    See companion article:

    • Structural titration of receptor ion channel GLIC gating by HS-AFM
      - Sep 04, 2018
  • You have access
    Collusion between neutralizing antibodies and other immune factions in the destruction of adenoviral vectors
    P. J. Klasse
    PNAS October 9, 2018 115 (41) 10201-10203; first published September 19, 2018. https://doi.org/10.1073/pnas.1814275115

    See companion article:

    • TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination
      - Sep 12, 2018

PNAS Plus Significance Statements

Brief statements written by the authors about the significance of their papers.
  • You have access
    PNAS Plus Significance Statements
    PNAS October 9, 2018 115 (41) 10204-10208; https://doi.org/10.1073/pnas.ss11541

Perspective

  • You have access
    Identity and novelty in the avian syrinx
    Evan P. Kingsley, Chad M. Eliason, Tobias Riede, Zhiheng Li, Tom W. Hiscock, Michael Farnsworth, Scott L. Thomson, Franz Goller, Clifford J. Tabin, and Julia A. Clarke
    PNAS October 9, 2018 115 (41) 10209-10217; first published September 24, 2018. https://doi.org/10.1073/pnas.1804586115

Physical Sciences

  • Applied Mathematics

    • You have access
      Symmetric coalescence of two hydraulic fractures
      Niall J. O’Keeffe, Zhong Zheng, Herbert E. Huppert, and P. F. Linden
      PNAS October 9, 2018 115 (41) 10228-10232; first published September 25, 2018. https://doi.org/10.1073/pnas.1809233115
  • Applied Physical Sciences

    • Open Access
      Stable Frank–Kasper phases of self-assembled, soft matter spheres
      Abhiram Reddy, Michael B. Buckley, Akash Arora, Frank S. Bates, Kevin D. Dorfman, and Gregory M. Grason
      PNAS October 9, 2018 115 (41) 10233-10238; first published September 24, 2018. https://doi.org/10.1073/pnas.1809655115
    • You have access
      Crimping-induced structural gradients explain the lasting strength of poly l-lactide bioresorbable vascular scaffolds during hydrolysis
      Karthik Ramachandran, Tiziana Di Luccio, Artemis Ailianou, Mary Beth Kossuth, James P. Oberhauser, and Julia A. Kornfield
      PNAS October 9, 2018 115 (41) 10239-10244; first published September 17, 2018. https://doi.org/10.1073/pnas.1807347115
  • Biophysics and Computational Biology

    • Open Access
      Parallel reaction pathways and noncovalent intermediates in thymidylate synthase revealed by experimental and computational tools
      Svetlana A. Kholodar, Ananda K. Ghosh, Katarzyna Świderek, Vicent Moliner, and Amnon Kohen
      PNAS October 9, 2018 115 (41) 10311-10314; first published September 24, 2018. https://doi.org/10.1073/pnas.1811059115
  • Chemistry

    • Open Access
      Phevamine A, a small molecule that suppresses plant immune responses
      Erinn M. O’Neill, Tatiana S. Mucyn, Jon B. Patteson, Omri M. Finkel, Eui-Hwan Chung, Joshua A. Baccile, Elisabetta Massolo, Frank C. Schroeder, Jeffery L. Dangl, and Bo Li
      PNAS October 9, 2018 115 (41) E9514-E9522; first published September 20, 2018. https://doi.org/10.1073/pnas.1803779115
    • Open Access
      Energy-dependent quenching adjusts the excitation diffusion length to regulate photosynthetic light harvesting
      Doran I. G. Bennett, Graham R. Fleming, and Kapil Amarnath
      PNAS October 9, 2018 115 (41) E9523-E9531; first published September 20, 2018. https://doi.org/10.1073/pnas.1806597115
    • Open Access
      SAR by kinetics for drug discovery in protein misfolding diseases
      Sean Chia, Johnny Habchi, Thomas C. T. Michaels, Samuel I. A. Cohen, Sara Linse, Christopher M. Dobson, Tuomas P. J. Knowles, and Michele Vendruscolo
      PNAS October 9, 2018 115 (41) 10245-10250; first published September 26, 2018. https://doi.org/10.1073/pnas.1807884115
    • You have access
      Predicting polymorphism in molecular crystals using orientational entropy
      Pablo M. Piaggi and Michele Parrinello
      PNAS October 9, 2018 115 (41) 10251-10256; first published September 20, 2018. https://doi.org/10.1073/pnas.1811056115
    • You have access
      Revised M06 density functional for main-group and transition-metal chemistry
      Ying Wang, Pragya Verma, Xinsheng Jin, Donald G. Truhlar, and Xiao He
      PNAS October 9, 2018 115 (41) 10257-10262; first published September 20, 2018. https://doi.org/10.1073/pnas.1810421115
    • You have access
      Two-dimensional dry ices with rich polymorphic and polyamorphic phase behavior
      Jaeil Bai, Joseph S. Francisco, and Xiao Cheng Zeng
      PNAS October 9, 2018 115 (41) 10263-10268; first published September 24, 2018. https://doi.org/10.1073/pnas.1809198115
    • You have access
      Multiscale wavelet decomposition of time-resolved X-ray diffraction signals in cyclohexadiene
      Vladimir Al. Osipov, Markus Kowalewski, and Shaul Mukamel
      PNAS October 9, 2018 115 (41) 10269-10274; first published September 25, 2018. https://doi.org/10.1073/pnas.1811983115
    • You have access
      Interferometric plasmonic imaging and detection of single exosomes
      Yuting Yang, Guangxia Shen, Hui Wang, Hongxia Li, Ting Zhang, Nongjian Tao, Xianting Ding, and Hui Yu
      PNAS October 9, 2018 115 (41) 10275-10280; first published September 24, 2018. https://doi.org/10.1073/pnas.1804548115
  • Earth, Atmospheric, and Planetary Sciences

    • Open Access
      Use of scenario ensembles for deriving seismic risk
      Tom R. Robinson, Nicholas J. Rosser, Alexander L. Densmore, Katie J. Oven, Surya N. Shrestha, and Ramesh Guragain
      PNAS October 9, 2018 115 (41) E9532-E9541; first published September 24, 2018. https://doi.org/10.1073/pnas.1807433115
    • You have access
      Sediment starvation destroys New York City marshes’ resistance to sea level rise
      Dorothy M. Peteet, Jonathan Nichols, Timothy Kenna, Clara Chang, James Browne, Mohammad Reza, Stephen Kovari, Louisa Liberman, and Stephanie Stern-Protz
      PNAS October 9, 2018 115 (41) 10281-10286; first published September 24, 2018. https://doi.org/10.1073/pnas.1715392115
    • You have access
      Origin and significance of Si and O isotope heterogeneities in Phanerozoic, Archean, and Hadean zircon
      Dustin Trail, Patrick Boehnke, Paul S. Savage, Ming-Chang Liu, Martha L. Miller, and Ilya Bindeman
      PNAS October 9, 2018 115 (41) 10287-10292; first published September 24, 2018. https://doi.org/10.1073/pnas.1808335115
    • You have access
      Earth’s outgoing longwave radiation linear due to H2O greenhouse effect
      Daniel D. B. Koll and Timothy W. Cronin
      PNAS October 9, 2018 115 (41) 10293-10298; first published September 25, 2018. https://doi.org/10.1073/pnas.1809868115
  • Engineering

    • You have access
      Conductively coupled flexible silicon electronic systems for chronic neural electrophysiology
      • From the Cover
      Jinghua Li, Enming Song, Chia-Han Chiang, Ki Jun Yu, Jahyun Koo, Haina Du, Yishan Zhong, Mackenna Hill, Charles Wang, Jize Zhang, Yisong Chen, Limei Tian, Yiding Zhong, Guanhua Fang, Jonathan Viventi, and John A. Rogers
      PNAS October 9, 2018 115 (41) E9542-E9549; first published September 18, 2018. https://doi.org/10.1073/pnas.1813187115
  • Mathematics

    • Open Access
      Mechanics of mouse blastocyst hatching revealed by a hydrogel-based microdeformation assay
      Karolis Leonavicius, Christophe Royer, Chris Preece, Benjamin Davies, John S. Biggins, and Shankar Srinivas
      PNAS October 9, 2018 115 (41) 10375-10380; first published September 19, 2018. https://doi.org/10.1073/pnas.1719930115
  • Statistics

    • Open Access
      Generalized least squares can overcome the critical threshold in respondent-driven sampling
      Sebastien Roch and Karl Rohe
      PNAS October 9, 2018 115 (41) 10299-10304; first published September 25, 2018. https://doi.org/10.1073/pnas.1706699115

Social Sciences

  • Psychological and Cognitive Sciences

    • You have access
      Neural basis of location-specific pupil luminance modulation
      Chin-An Wang and Douglas P. Munoz
      PNAS October 9, 2018 115 (41) 10446-10451; first published September 24, 2018. https://doi.org/10.1073/pnas.1809668115
    • Open Access
      Movement kinematics drive chain selection toward intention detection
      Marco Soriano, Andrea Cavallo, Alessandro D’Ausilio, Cristina Becchio, and Luciano Fadiga
      PNAS October 9, 2018 115 (41) 10452-10457; first published September 21, 2018. https://doi.org/10.1073/pnas.1809825115
  • Social Sciences

    • Open Access
      Generalized least squares can overcome the critical threshold in respondent-driven sampling
      Sebastien Roch and Karl Rohe
      PNAS October 9, 2018 115 (41) 10299-10304; first published September 25, 2018. https://doi.org/10.1073/pnas.1706699115

Biological Sciences

  • Applied Biological Sciences

    • Open Access
      Glyphosate perturbs the gut microbiota of honey bees
      Erick V. S. Motta, Kasie Raymann, and Nancy A. Moran
      PNAS October 9, 2018 115 (41) 10305-10310; first published September 24, 2018. https://doi.org/10.1073/pnas.1803880115
  • Biochemistry

    • You have access
      ZFAND5/ZNF216 is an activator of the 26S proteasome that stimulates overall protein degradation
      Donghoon Lee, Shinichi Takayama, and Alfred L. Goldberg
      PNAS October 9, 2018 115 (41) E9550-E9559; first published September 25, 2018. https://doi.org/10.1073/pnas.1809934115
    • Open Access
      ATP hydrolysis-coupled peptide translocation mechanism of Mycobacterium tuberculosis ClpB
      Hongjun Yu, Tania J. Lupoli, Amanda Kovach, Xing Meng, Gongpu Zhao, Carl F. Nathan, and Huilin Li
      PNAS October 9, 2018 115 (41) E9560-E9569; first published September 26, 2018. https://doi.org/10.1073/pnas.1810648115
    • Open Access
      Parallel reaction pathways and noncovalent intermediates in thymidylate synthase revealed by experimental and computational tools
      Svetlana A. Kholodar, Ananda K. Ghosh, Katarzyna Świderek, Vicent Moliner, and Amnon Kohen
      PNAS October 9, 2018 115 (41) 10311-10314; first published September 24, 2018. https://doi.org/10.1073/pnas.1811059115
    • Open Access
      Single-stranded telomere-binding protein employs a dual rheostat for binding affinity and specificity that drives function
      Leslie W. Glustrom, Kenneth R. Lyon, Margherita Paschini, Cynthia M. Reyes, Nicholas V. Parsonnet, Tasha B. Toro, Victoria Lundblad, and Deborah S. Wuttke
      PNAS October 9, 2018 115 (41) 10315-10320; first published September 24, 2018. https://doi.org/10.1073/pnas.1722147115
  • Biophysics and Computational Biology

    • Open Access
      SAR by kinetics for drug discovery in protein misfolding diseases
      Sean Chia, Johnny Habchi, Thomas C. T. Michaels, Samuel I. A. Cohen, Sara Linse, Christopher M. Dobson, Tuomas P. J. Knowles, and Michele Vendruscolo
      PNAS October 9, 2018 115 (41) 10245-10250; first published September 26, 2018. https://doi.org/10.1073/pnas.1807884115
    • You have access
      On the control of the proton current in the voltage-gated proton channel Hv1
      Myungjin Lee, Chen Bai, Mikolaj Feliks, Raphael Alhadeff, and Arieh Warshel
      PNAS October 9, 2018 115 (41) 10321-10326; first published September 25, 2018. https://doi.org/10.1073/pnas.1809766115
    • You have access
      Exploring the free-energy landscape of GPCR activation
      Raphael Alhadeff, Igor Vorobyov, Han Wool Yoon, and Arieh Warshel
      PNAS October 9, 2018 115 (41) 10327-10332; first published September 26, 2018. https://doi.org/10.1073/pnas.1810316115
    • You have access
      Structural titration of receptor ion channel GLIC gating by HS-AFM
      • From the Cover
      Yi Ruan, Kevin Kao, Solène Lefebvre, Arin Marchesi, Pierre-Jean Corringer, Richard K. Hite, and Simon Scheuring
      PNAS October 9, 2018 115 (41) 10333-10338; first published September 4, 2018. https://doi.org/10.1073/pnas.1805621115

      See companion article:

      • Direct visualization of ion-channel gating in a native environment
        - Sep 26, 2018
    • You have access
      The interaction of talin with the cell membrane is essential for integrin activation and focal adhesion formation
      Krishna Chinthalapudi, Erumbi S. Rangarajan, and Tina Izard
      PNAS October 9, 2018 115 (41) 10339-10344; first published September 25, 2018. https://doi.org/10.1073/pnas.1806275115
    • Open Access
      Structural evidence for the roles of divalent cations in actin polymerization and activation of ATP hydrolysis
      Clement P. M. Scipion, Umesh Ghoshdastider, Fernando J. Ferrer, Tsz-Ying Yuen, Jantana Wongsantichon, and Robert C. Robinson
      PNAS October 9, 2018 115 (41) 10345-10350; first published September 25, 2018. https://doi.org/10.1073/pnas.1806394115
  • Cell Biology

    • You have access
      Role for ERK1/2-dependent activation of FCHSD2 in cancer cell-selective regulation of clathrin-mediated endocytosis
      Guan-Yu Xiao, Aparna Mohanakrishnan, and Sandra L. Schmid
      PNAS October 9, 2018 115 (41) E9570-E9579; first published September 24, 2018. https://doi.org/10.1073/pnas.1810209115
    • You have access
      ERβ-mediated induction of cystatins results in suppression of TGFβ signaling and inhibition of triple-negative breast cancer metastasis
      Jordan M. Reese, Elizabeth S. Bruinsma, Adam W. Nelson, Igor Chernukhin, Jason S. Carroll, Ying Li, Malayannan Subramaniam, Vera J. Suman, Vivian Negron, David G. Monroe, James N. Ingle, Matthew P. Goetz, and John R. Hawse
      PNAS October 9, 2018 115 (41) E9580-E9589; first published September 26, 2018. https://doi.org/10.1073/pnas.1807751115
    • Open Access
      Mechanism of drug extrusion by brain endothelial cells via lysosomal drug trapping and disposal by neutrophils
      Andreas Noack, Birthe Gericke, Maren von Köckritz-Blickwede, Arne Menze, Sandra Noack, Ingo Gerhauser, Felix Osten, Hassan Y. Naim, and Wolfgang Löscher
      PNAS October 9, 2018 115 (41) E9590-E9599; first published September 25, 2018. https://doi.org/10.1073/pnas.1719642115
    • Open Access
      BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
      Andrew G. Li, Elizabeth C. Murphy, Aedin C. Culhane, Emily Powell, Hua Wang, Roderick T. Bronson, Thanh Von, Anita Giobbie-Hurder, Rebecca S. Gelman, Kimberly J. Briggs, Helen Piwnica-Worms, Jean J. Zhao, Andrew L. Kung, William G. Kaelin Jr., and David M. Livingston
      PNAS October 9, 2018 115 (41) E9600-E9609; first published September 25, 2018. https://doi.org/10.1073/pnas.1807112115
    • You have access
      VEGF-B is a potent antioxidant
      Pachiappan Arjunan, Xianchai Lin, Zhongshu Tang, Yuxiang Du, Anil Kumar, Lixian Liu, Xiangke Yin, Lijuan Huang, Wei Chen, Qishan Chen, Zhimin Ye, Shasha Wang, Haiqing Kuang, Linbin Zhou, Kai Xu, Xue Chen, Haitao Zeng, Weisi Lu, Yihai Cao, Yizhi Liu, Chen Zhao, and Xuri Li
      PNAS October 9, 2018 115 (41) 10351-10356; first published September 24, 2018. https://doi.org/10.1073/pnas.1801379115
    • You have access
      PAX5-ELN oncoprotein promotes multistep B-cell acute lymphoblastic leukemia in mice
      Laura Jamrog, Guillaume Chemin, Vincent Fregona, Lucie Coster, Marlène Pasquet, Chloé Oudinet, Nelly Rouquié, Naïs Prade, Stéphanie Lagarde, Charlotte Cresson, Sylvie Hébrard, Ngoc Sa Nguyen Huu, Marina Bousquet, Cathy Quelen, Pierre Brousset, Stéphane J. C. Mancini, Eric Delabesse, Ahmed Amine Khamlichi, Bastien Gerby, and Cyril Broccardo
      PNAS October 9, 2018 115 (41) 10357-10362; first published September 26, 2018. https://doi.org/10.1073/pnas.1721678115
    • You have access
      The Atg2-Atg18 complex tethers pre-autophagosomal membranes to the endoplasmic reticulum for autophagosome formation
      Tetsuya Kotani, Hiromi Kirisako, Michiko Koizumi, Yoshinori Ohsumi, and Hitoshi Nakatogawa
      PNAS October 9, 2018 115 (41) 10363-10368; first published September 25, 2018. https://doi.org/10.1073/pnas.1806727115
    • Open Access
      Nebulin stiffens the thin filament and augments cross-bridge interaction in skeletal muscle
      Balázs Kiss, Eun-Jeong Lee, Weikang Ma, Frank W. Li, Paola Tonino, Srboljub M. Mijailovich, Thomas C. Irving, and Henk L. Granzier
      PNAS October 9, 2018 115 (41) 10369-10374; first published September 24, 2018. https://doi.org/10.1073/pnas.1804726115
  • Developmental Biology

    • Open Access
      Mechanics of mouse blastocyst hatching revealed by a hydrogel-based microdeformation assay
      Karolis Leonavicius, Christophe Royer, Chris Preece, Benjamin Davies, John S. Biggins, and Shankar Srinivas
      PNAS October 9, 2018 115 (41) 10375-10380; first published September 19, 2018. https://doi.org/10.1073/pnas.1719930115
    • Open Access
      Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis
      Suk-Hyun Hong, Sungsoon Fang, Benson C. Lu, Russell Nofsinger, Yasuhiko Kawakami, Glenda L. Castro, Yunqiang Yin, Chengqi Lin, Ruth T. Yu, Michael Downes, Juan Carlos Izpisúa Belmonte, Ali Shilatifard, and Ronald M. Evans
      PNAS October 9, 2018 115 (41) 10381-10386; first published September 25, 2018. https://doi.org/10.1073/pnas.1809480115
    • You have access
      Role of transcription complexes in the formation of the basal methylation pattern in early development
      Razi Greenfield, Amalia Tabib, Ilana Keshet, Joshua Moss, Ofra Sabag, Alon Goren, and Howard Cedar
      PNAS October 9, 2018 115 (41) 10387-10391; first published September 26, 2018. https://doi.org/10.1073/pnas.1804755115
  • Ecology

    • You have access
      Sediment starvation destroys New York City marshes’ resistance to sea level rise
      Dorothy M. Peteet, Jonathan Nichols, Timothy Kenna, Clara Chang, James Browne, Mohammad Reza, Stephen Kovari, Louisa Liberman, and Stephanie Stern-Protz
      PNAS October 9, 2018 115 (41) 10281-10286; first published September 24, 2018. https://doi.org/10.1073/pnas.1715392115
    • You have access
      Contrasting dynamics and trait controls in first-order root compared with leaf litter decomposition
      Tao Sun, Sarah E. Hobbie, Björn Berg, Hongguang Zhang, Qingkui Wang, Zhengwen Wang, and Stephan Hättenschwiler
      PNAS October 9, 2018 115 (41) 10392-10397; first published September 25, 2018. https://doi.org/10.1073/pnas.1716595115
  • Evolution

    • You have access
      Versatility of multivalent orientation, inverted meiosis, and rescued fitness in holocentric chromosomal hybrids
      • From the Cover
      Vladimir A. Lukhtanov, Vlad Dincă, Magne Friberg, Jindra Šíchová, Martin Olofsson, Roger Vila, František Marec, and Christer Wiklund
      PNAS October 9, 2018 115 (41) E9610-E9619; first published September 28, 2018. https://doi.org/10.1073/pnas.1802610115
    • You have access
      Genomic responses to selection for tame/aggressive behaviors in the silver fox (Vulpes vulpes)
      Xu Wang, Lenore Pipes, Lyudmila N. Trut, Yury Herbeck, Anastasiya V. Vladimirova, Rimma G. Gulevich, Anastasiya V. Kharlamova, Jennifer L. Johnson, Gregory M. Acland, Anna V. Kukekova, and Andrew G. Clark
      PNAS October 9, 2018 115 (41) 10398-10403; first published September 18, 2018. https://doi.org/10.1073/pnas.1800889115
  • Genetics

    • Open Access
      Mutations of mitochondrial DNA are not major contributors to aging of fruit flies
      Timo E. S. Kauppila, Ana Bratic, Martin Borch Jensen, Francesca Baggio, Linda Partridge, Heinrich Jasper, Sebastian Grönke, and Nils-Göran Larsson
      PNAS October 9, 2018 115 (41) E9620-E9629; first published September 24, 2018. https://doi.org/10.1073/pnas.1721683115
  • Immunology and Inflammation

    • Open Access
      Cochaperone Mzb1 is a key effector of Blimp1 in plasma cell differentiation and β1-integrin function
      Virginia Andreani, Senthilkumar Ramamoorthy, Abhinav Pandey, Ekaterina Lupar, Stephen L. Nutt, Tim Lämmermann, and Rudolf Grosschedl
      PNAS October 9, 2018 115 (41) E9630-E9639; first published September 26, 2018. https://doi.org/10.1073/pnas.1809739115
    • You have access
      MAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotype
      Emilie Plantamura, Amiran Dzutsev, Mathias Chamaillard, Sophia Djebali, Lyvia Moudombi, Lilia Boucinha, Morgan Grau, Claire Macari, David Bauché, Oana Dumitrescu, Jean-Philippe Rasigade, Saskia Lippens, Michelina Plateroti, Elsa Kress, Annabelle Cesaro, Clovis Bondu, Ulrike Rothermel, Mathias Heikenwälder, Gerard Lina, Azzak Bentaher-Belaaouaj, Julien C. Marie, Christophe Caux, Giorgio Trinchieri, Jacqueline Marvel, and Marie-Cecile Michallet
      PNAS October 9, 2018 115 (41) 10404-10409; first published September 24, 2018. https://doi.org/10.1073/pnas.1722372115
    • You have access
      Siglec-7 engagement by GBS β-protein suppresses pyroptotic cell death of natural killer cells
      Jerry J. Fong, Chih-Ming Tsai, Sudeshna Saha, Victor Nizet, Ajit Varki, and Jack D. Bui
      PNAS October 9, 2018 115 (41) 10410-10415; first published September 25, 2018. https://doi.org/10.1073/pnas.1804108115
    • You have access
      Optimal protection against Salmonella infection requires noncirculating memory
      Joseph M. Benoun, Newton G. Peres, Nancy Wang, Oanh H. Pham, Victoria L. Rudisill, Zachary N. Fogassy, Paul G. Whitney, Daniel Fernandez-Ruiz, Thomas Gebhardt, Quynh-Mai Pham, Lynn Puddington, Sammy Bedoui, Richard A. Strugnell, and Stephen J. McSorley
      PNAS October 9, 2018 115 (41) 10416-10421; first published September 25, 2018. https://doi.org/10.1073/pnas.1808339115
  • Medical Sciences

    • You have access
      Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
      Jie Lan, Haiquan Lu, Debangshu Samanta, Shaima Salman, You Lu, and Gregg L. Semenza
      PNAS October 9, 2018 115 (41) E9640-E9648; first published September 21, 2018. https://doi.org/10.1073/pnas.1809695115
  • Microbiology

    • Open Access
      Phevamine A, a small molecule that suppresses plant immune responses
      Erinn M. O’Neill, Tatiana S. Mucyn, Jon B. Patteson, Omri M. Finkel, Eui-Hwan Chung, Joshua A. Baccile, Elisabetta Massolo, Frank C. Schroeder, Jeffery L. Dangl, and Bo Li
      PNAS October 9, 2018 115 (41) E9514-E9522; first published September 20, 2018. https://doi.org/10.1073/pnas.1803779115
    • You have access
      Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections
      Mario D. Garcia, Sheena M. H. Chua, Yu-Shang Low, Yu-Ting Lee, Kylie Agnew-Francis, Jian-Guo Wang, Amanda Nouwens, Thierry Lonhienne, Craig M. Williams, James A. Fraser, and Luke W. Guddat
      PNAS October 9, 2018 115 (41) E9649-E9658; first published September 24, 2018. https://doi.org/10.1073/pnas.1809422115
    • You have access
      IL-15 regulates susceptibility of CD4+ T cells to HIV infection
      Lara Manganaro, Patrick Hong, Matthew M. Hernandez, Dionne Argyle, Lubbertus C. F. Mulder, Uma Potla, Felipe Diaz-Griffero, Benhur Lee, Ana Fernandez-Sesma, and Viviana Simon
      PNAS October 9, 2018 115 (41) E9659-E9667; first published September 26, 2018. https://doi.org/10.1073/pnas.1806695115
    • Open Access
      Genomic blueprint of a relapsing fever pathogen in 15th century Scandinavia
      Meriam Guellil, Oliver Kersten, Amine Namouchi, Egil L. Bauer, Michael Derrick, Anne Ø. Jensen, Nils C. Stenseth, and Barbara Bramanti
      PNAS October 9, 2018 115 (41) 10422-10427; first published September 24, 2018. https://doi.org/10.1073/pnas.1807266115
    • Open Access
      Comparative immunogenicity and efficacy of equivalent outer membrane vesicle and glycoconjugate vaccines against nontyphoidal Salmonella
      Francesca Micoli, Simona Rondini, Renzo Alfini, Luisa Lanzilao, Francesca Necchi, Aurel Negrea, Omar Rossi, Cornelia Brandt, Simon Clare, Pietro Mastroeni, Rino Rappuoli, Allan Saul, and Calman A. MacLennan
      PNAS October 9, 2018 115 (41) 10428-10433; first published September 27, 2018. https://doi.org/10.1073/pnas.1807655115
    • You have access
      Human Endogenous Retrovirus-K HML-2 integration within RASGRF2 is associated with intravenous drug abuse and modulates transcription in a cell-line model
      Timokratis Karamitros, Tara Hurst, Emanuele Marchi, Eirini Karamichali, Urania Georgopoulou, Andreas Mentis, Joey Riepsaame, Audrey Lin, Dimitrios Paraskevis, Angelos Hatzakis, John McLauchlan, Aris Katzourakis, and Gkikas Magiorkinis
      PNAS October 9, 2018 115 (41) 10434-10439; first published September 24, 2018. https://doi.org/10.1073/pnas.1811940115
    • Open Access
      TRIM21 mediates antibody inhibition of adenovirus-based gene delivery and vaccination
      • From the Cover
      Maria Bottermann, Stian Foss, Laurens M. van Tienen, Marina Vaysburd, James Cruickshank, Kevin O’Connell, Jessica Clark, Keith Mayes, Katie Higginson, Jack C. Hirst, Martin B. McAdam, Greg Slodkowicz, Edward Hutchinson, Patrycja Kozik, Jan Terje Andersen, and Leo C. James
      PNAS October 9, 2018 115 (41) 10440-10445; first published September 12, 2018. https://doi.org/10.1073/pnas.1806314115

      See companion article:

      • Collusion between neutralizing antibodies and other immune factions in the destruction of adenoviral vectors
        - Sep 19, 2018
  • Neuroscience

    • You have access
      Let-7i inhibition enhances progesterone-induced functional recovery in a mouse model of ischemia
      Trinh Nguyen, Chang Su, and Meharvan Singh
      PNAS October 9, 2018 115 (41) E9668-E9677; first published September 20, 2018. https://doi.org/10.1073/pnas.1803384115
    • You have access
      FUS interacts with ATP synthase beta subunit and induces mitochondrial unfolded protein response in cellular and animal models
      Jianwen Deng, Peng Wang, Xiaoping Chen, Haipeng Cheng, Jianghong Liu, Kazuo Fushimi, Li Zhu, and Jane Y. Wu
      PNAS October 9, 2018 115 (41) E9678-E9686; first published September 24, 2018. https://doi.org/10.1073/pnas.1806655115
    • You have access
      Blood-derived plasminogen drives brain inflammation and plaque deposition in a mouse model of Alzheimer’s disease
      Sarah K. Baker, Zu-Lin Chen, Erin H. Norris, Alexey S. Revenko, A. Robert MacLeod, and Sidney Strickland
      PNAS October 9, 2018 115 (41) E9687-E9696; first published September 25, 2018. https://doi.org/10.1073/pnas.1811172115
    • Open Access
      Single-molecule analysis of endogenous β-actin mRNA trafficking reveals a mechanism for compartmentalized mRNA localization in axons
      Benita Turner-Bridger, Maximillian Jakobs, Leila Muresan, Hovy Ho-Wai Wong, Kristian Franze, William A. Harris, and Christine E. Holt
      PNAS October 9, 2018 115 (41) E9697-E9706; first published September 25, 2018. https://doi.org/10.1073/pnas.1806189115
    • You have access
      Activation of autophagy rescues synaptic and cognitive deficits in fragile X mice
      Jingqi Yan, Morgan W. Porch, Brenda Court-Vazquez, Michael V. L. Bennett, and R. Suzanne Zukin
      PNAS October 9, 2018 115 (41) E9707-E9716; first published September 21, 2018. https://doi.org/10.1073/pnas.1808247115
    • Open Access
      ASTN2 modulates synaptic strength by trafficking and degradation of surface proteins
      Hourinaz Behesti, Taylor R. Fore, Peter Wu, Zachi Horn, Mary Leppert, Court Hull, and Mary E. Hatten
      PNAS October 9, 2018 115 (41) E9717-E9726; first published September 21, 2018. https://doi.org/10.1073/pnas.1809382115
    • Open Access
      Genetically defined cellular correlates of the baseline brain MRI signal
      Jie Wen, Manu S. Goyal, Serguei V. Astafiev, Marcus E. Raichle, and Dmitriy A. Yablonskiy
      PNAS October 9, 2018 115 (41) E9727-E9736; first published September 25, 2018. https://doi.org/10.1073/pnas.1808121115
    • You have access
      Neural basis of location-specific pupil luminance modulation
      Chin-An Wang and Douglas P. Munoz
      PNAS October 9, 2018 115 (41) 10446-10451; first published September 24, 2018. https://doi.org/10.1073/pnas.1809668115
    • Open Access
      Movement kinematics drive chain selection toward intention detection
      Marco Soriano, Andrea Cavallo, Alessandro D’Ausilio, Cristina Becchio, and Luciano Fadiga
      PNAS October 9, 2018 115 (41) 10452-10457; first published September 21, 2018. https://doi.org/10.1073/pnas.1809825115
    • You have access
      A single phosphorylation site of SIK3 regulates daily sleep amounts and sleep need in mice
      Takato Honda, Tomoyuki Fujiyama, Chika Miyoshi, Aya Ikkyu, Noriko Hotta-Hirashima, Satomi Kanno, Seiya Mizuno, Fumihiro Sugiyama, Satoru Takahashi, Hiromasa Funato, and Masashi Yanagisawa
      PNAS October 9, 2018 115 (41) 10458-10463; first published September 25, 2018. https://doi.org/10.1073/pnas.1810823115
    • You have access
      Axonal plasticity associated with perceptual learning in adult macaque primary visual cortex
      Timo van Kerkoerle, Sally A. Marik, Stephan Meyer zum Alten Borgloh, and Charles D. Gilbert
      PNAS October 9, 2018 115 (41) 10464-10469; first published September 27, 2018. https://doi.org/10.1073/pnas.1812932115
    • You have access
      Desert ants possess distinct memories for food and nest odors
      Roman Huber and Markus Knaden
      PNAS October 9, 2018 115 (41) 10470-10474; first published September 24, 2018. https://doi.org/10.1073/pnas.1809433115
    • You have access
      Stimulation of AMPK prevents degeneration of photoreceptors and the retinal pigment epithelium
      Lei Xu, Li Kong, Jiangang Wang, and John D. Ash
      PNAS October 9, 2018 115 (41) 10475-10480; first published September 24, 2018. https://doi.org/10.1073/pnas.1802724115
    • You have access
      Small molecule inhibits α-synuclein aggregation, disrupts amyloid fibrils, and prevents degeneration of dopaminergic neurons
      Jordi Pujols, Samuel Peña-Díaz, Diana F. Lázaro, Francesca Peccati, Francisca Pinheiro, Danilo González, Anita Carija, Susanna Navarro, María Conde-Giménez, Jesús García, Salvador Guardiola, Ernest Giralt, Xavier Salvatella, Javier Sancho, Mariona Sodupe, Tiago Fleming Outeiro, Esther Dalfó, and Salvador Ventura
      PNAS October 9, 2018 115 (41) 10481-10486; first published September 24, 2018. https://doi.org/10.1073/pnas.1804198115
    • You have access
      Rapid stimulation of human dentate gyrus function with acute mild exercise
      Kazuya Suwabe, Kyeongho Byun, Kazuki Hyodo, Zachariah M. Reagh, Jared M. Roberts, Akira Matsushita, Kousaku Saotome, Genta Ochi, Takemune Fukuie, Kenji Suzuki, Yoshiyuki Sankai, Michael A. Yassa, and Hideaki Soya
      PNAS October 9, 2018 115 (41) 10487-10492; first published September 24, 2018. https://doi.org/10.1073/pnas.1805668115

      See companion article:

      • Reply to Gronwald et al.: Exercise intensity does indeed matter; maximal oxygen uptake is the gold-standard indicator
        - Dec 17, 2018
    • You have access
      Striatal dopamine 2 receptor upregulation during development predisposes to diet-induced obesity by reducing energy output in mice
      Marie A. Labouesse, Andrea M. Sartori, Oliver Weinmann, Eleanor H. Simpson, Christoph Kellendonk, and Ulrike Weber-Stadlbauer
      PNAS October 9, 2018 115 (41) 10493-10498; first published September 25, 2018. https://doi.org/10.1073/pnas.1800171115
    • Open Access
      Bottom-up saliency and top-down learning in the primary visual cortex of monkeys
      Yin Yan, Li Zhaoping, and Wu Li
      PNAS October 9, 2018 115 (41) 10499-10504; first published September 25, 2018. https://doi.org/10.1073/pnas.1803854115
    • Open Access
      Functionally specific optogenetic modulation in primate visual cortex
      Mykyta M. Chernov, Robert M. Friedman, Gang Chen, Gene R. Stoner, and Anna Wang Roe
      PNAS October 9, 2018 115 (41) 10505-10510; first published September 26, 2018. https://doi.org/10.1073/pnas.1802018115
  • Pharmacology

    • You have access
      l-Serine–modified polyamidoamine dendrimer as a highly potent renal targeting drug carrier
      Satoru Matsuura, Hidemasa Katsumi, Hiroe Suzuki, Natsuko Hirai, Hidetaka Hayashi, Kazuhiro Koshino, Takahiro Higuchi, Yusuke Yagi, Hiroyuki Kimura, Toshiyasu Sakane, and Akira Yamamoto
      PNAS October 9, 2018 115 (41) 10511-10516; first published September 24, 2018. https://doi.org/10.1073/pnas.1808168115
  • Physiology

    • You have access
      Cold exposure causes cell death by depolarization-mediated Ca2+ overload in a chill-susceptible insect
      Jeppe Seamus Bayley, Christian Bak Winther, Mads Kuhlmann Andersen, Camilla Grønkjær, Ole Bækgaard Nielsen, Thomas Holm Pedersen, and Johannes Overgaard
      PNAS October 9, 2018 115 (41) E9737-E9744; first published September 25, 2018. https://doi.org/10.1073/pnas.1813532115
    • Open Access
      Nanoscale remodeling of ryanodine receptor cluster size underlies cerebral microvascular dysfunction in Duchenne muscular dystrophy
      • From the Cover
      Harry A. T. Pritchard, Paulo W. Pires, Evan Yamasaki, Pratish Thakore, and Scott Earley
      PNAS October 9, 2018 115 (41) E9745-E9752; first published September 4, 2018. https://doi.org/10.1073/pnas.1804593115

      See companion article:

      • Ryanodine receptor cluster size sets the tone in cerebral smooth muscle
        - Sep 26, 2018
  • Plant Biology

    • Open Access
      Energy-dependent quenching adjusts the excitation diffusion length to regulate photosynthetic light harvesting
      Doran I. G. Bennett, Graham R. Fleming, and Kapil Amarnath
      PNAS October 9, 2018 115 (41) E9523-E9531; first published September 20, 2018. https://doi.org/10.1073/pnas.1806597115
    • Open Access
      Distinct modes of derepression of an Arabidopsis immune receptor complex by two different bacterial effectors
      • Inaugural Article
      Yan Ma, Hailong Guo, Lanxi Hu, Paula Pons Martinez, Panagiotis N. Moschou, Volkan Cevik, Pingtao Ding, Zane Duxbury, Panagiotis F. Sarris, and Jonathan D. G. Jones
      PNAS October 9, 2018 115 (41) 10218-10227; first published September 25, 2018. https://doi.org/10.1073/pnas.1811858115

      See companion article:

      • Profile of Jonathan D. G. Jones
        - Sep 24, 2018
    • You have access
      Structure of a PSI–LHCI–cyt b6f supercomplex in Chlamydomonas reinhardtii promoting cyclic electron flow under anaerobic conditions
      Janina Steinbeck, Ian L. Ross, Rosalba Rothnagel, Philipp Gäbelein, Stefan Schulze, Nichole Giles, Rubbiya Ali, Rohan Drysdale, Emma Sierecki, Yann Gambin, Henning Stahlberg, Yuichiro Takahashi, Michael Hippler, and Ben Hankamer
      PNAS October 9, 2018 115 (41) 10517-10522; first published September 25, 2018. https://doi.org/10.1073/pnas.1809973115
    • You have access
      Dawn and photoperiod sensing by phytochrome A
      Daniel D. Seaton, Gabriela Toledo-Ortiz, Ashwin Ganpudi, Akane Kubota, Takato Imaizumi, and Karen J. Halliday
      PNAS October 9, 2018 115 (41) 10523-10528; first published September 25, 2018. https://doi.org/10.1073/pnas.1803398115

Correction (Online Only)

  • You have access
    Correction for Mittal et al., Codon usage influences fitness through RNA toxicity
    PNAS October 9, 2018 115 (41) E9753; first published October 1, 2018. https://doi.org/10.1073/pnas.1815812115

SI Correction (Online Only)

  • You have access
    Correction to Supporting Information for Reid-Bayliss and Loeb, Accurate RNA consensus sequencing for high-fidelity detection of transcriptional mutagenesis-induced epimutations
    PNAS October 9, 2018 115 (41) E9754; first published October 1, 2018. https://doi.org/10.1073/pnas.1815350115
PreviousNext
Back to top

Browse PNAS issues

In this issue

Proceedings of the National Academy of Sciences: 115 (41)
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Masthead (PDF)
Sign up for alerts

Jump to

  • This Week in PNAS
  • Letters (Online Only)
  • Inner Workings
  • Profile
  • Commentaries
  • PNAS Plus Significance Statements
  • Perspective
  • Physical Sciences
  • Social Sciences
  • Biological Sciences
  • Correction (Online Only)
  • SI Correction (Online Only)

PNAS Highlights. Top research, news, and commentary delivered straight to your inbox.

Site Logo
Powered by HighWire
  • Submit Manuscript
  • Twitter
  • Facebook
  • RSS Feeds
  • Email Alerts

Articles

  • Current Issue
  • Special Feature Articles – Most Recent
  • List of Issues

PNAS Portals

  • Anthropology
  • Chemistry
  • Classics
  • Front Matter
  • Physics
  • Sustainability Science
  • Teaching Resources

Information

  • Authors
  • Editorial Board
  • Reviewers
  • Librarians
  • Press
  • Site Map
  • PNAS Updates

Feedback    Privacy/Legal

Copyright © 2021 National Academy of Sciences. Online ISSN 1091-6490