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Table of Contents
October 23, 2018; vol. 115 no. 43
This Week in PNAS
Opinion
Leading scientists discuss current issues.
- You have accessOpinion: Advocating for science progress as a human right
- Front Matter
S. Porsdam Mann, Y. Donders, C. Mitchell, V. J. Bradley, M. F. Chou, M. Mann, G. Church, and H. Porsdam
PNAS Plus Significance Statements
Brief statements written by the authors about the significance of their papers.
Perspective
- You have accessProlonging healthy aging: Longevity vitamins and proteinsBruce N. AmesPNAS October 23, 2018 115 (43) 10836-10844; first published October 15, 2018. https://doi.org/10.1073/pnas.1809045115
Trisections of Smooth Manifolds Special Feature (Free Online)
Introduction
- You have accessTrisections of 4-manifolds
- From the Cover
Robion KirbyPNAS October 23, 2018 115 (43) 10853-10856; first published October 22, 2018. https://doi.org/10.1073/pnas.1717166115
Research Articles
- You have accessA new invariant of 4-manifoldsRobion Kirby and Abigail ThompsonPNAS October 23, 2018 115 (43) 10857-10860; first published October 22, 2018. https://doi.org/10.1073/pnas.1718953115
- You have accessTrisections of 4-manifolds with boundaryNickolas A. Castro, David T. Gay, and Juanita Pinzón-CaicedoPNAS October 23, 2018 115 (43) 10861-10868; first published October 22, 2018. https://doi.org/10.1073/pnas.1717170115
- You have accessCalculating the homology and intersection form of a 4-manifold from a trisection diagramPeter Feller, Michael Klug, Trenton Schirmer, and Drew ZemkePNAS October 23, 2018 115 (43) 10869-10874; first published October 22, 2018. https://doi.org/10.1073/pnas.1717176115
- You have accessFunctoriality of group trisectionsMichael KlugPNAS October 23, 2018 115 (43) 10875-10879; first published October 22, 2018. https://doi.org/10.1073/pnas.1717167115
- You have accessBridge trisections of knotted surfaces in 4-manifoldsJeffrey Meier and Alexander ZupanPNAS October 23, 2018 115 (43) 10880-10886; first published October 22, 2018. https://doi.org/10.1073/pnas.1717171115
- You have accessCharacterizing Dehn surgeries on links via trisectionsJeffrey Meier and Alexander ZupanPNAS October 23, 2018 115 (43) 10887-10893; first published October 22, 2018. https://doi.org/10.1073/pnas.1717187115
- You have accessSimplified broken Lefschetz fibrations and trisections of 4-manifoldsR. İnanç Baykur and Osamu SaekiPNAS October 23, 2018 115 (43) 10894-10900; first published October 22, 2018. https://doi.org/10.1073/pnas.1717175115
- You have accessComputing trisections of 4-manifoldsMark Bell, Joel Hass, Joachim Hyam Rubinstein, and Stephan TillmannPNAS October 23, 2018 115 (43) 10901-10907; first published October 22, 2018. https://doi.org/10.1073/pnas.1717173115
- You have accessGeneralized trisections in all dimensionsJ. Hyam Rubinstein and Stephan TillmannPNAS October 23, 2018 115 (43) 10908-10913; first published October 22, 2018. https://doi.org/10.1073/pnas.1718961115
Physical Sciences
Applied Mathematics
- Open AccessRandomly distributed embedding making short-term high-dimensional data predictableHuanfei Ma, Siyang Leng, Kazuyuki Aihara, Wei Lin, and Luonan ChenPNAS October 23, 2018 115 (43) E9994-E10002; first published October 8, 2018. https://doi.org/10.1073/pnas.1802987115
Applied Physical Sciences
- Open AccessVerifying Larché–Cahn elasticity, a milestone of 20th-century thermodynamicsShan Shi, Jürgen Markmann, and Jörg WeissmüllerPNAS October 23, 2018 115 (43) 10914-10919; first published October 5, 2018. https://doi.org/10.1073/pnas.1809355115
Chemistry
- Open AccessNonproteinogenic deep mutational scanning of linear and cyclic peptidesJoseph M. Rogers, Toby Passioura, and Hiroaki SugaPNAS October 23, 2018 115 (43) 10959-10964; first published October 9, 2018. https://doi.org/10.1073/pnas.1809901115
- You have accessProtein shape modulates crowding effectsAlex J. Guseman, Gerardo M. Perez Goncalves, Shannon L. Speer, Gregory B. Young, and Gary J. PielakPNAS October 23, 2018 115 (43) 10965-10970; first published October 9, 2018. https://doi.org/10.1073/pnas.1810054115
- Open AccessNative-state imaging of calcifying and noncalcifying microalgae reveals similarities in their calcium storage organellesAssaf Gal, Andrea Sorrentino, Keren Kahil, Eva Pereiro, Damien Faivre, and André ScheffelPNAS October 23, 2018 115 (43) 11000-11005; first published October 4, 2018. https://doi.org/10.1073/pnas.1804139115
Earth, Atmospheric, and Planetary Sciences
- Open AccessVolatile loss following cooling and accretion of the Moon revealed by chromium isotopesPaolo A. Sossi, Frédéric Moynier, and Kirsten van ZuilenPNAS October 23, 2018 115 (43) 10920-10925; first published October 8, 2018. https://doi.org/10.1073/pnas.1809060115
- Open AccessRedox-dependent niche differentiation provides evidence for multiple bacterial sources of glycerol tetraether lipids in lakesYuki Weber, Jaap S. Sinninghe Damsté, Jakob Zopfi, Cindy De Jonge, Adrian Gilli, Carsten J. Schubert, Fabio Lepori, Moritz F. Lehmann, and Helge NiemannPNAS October 23, 2018 115 (43) 10926-10931; first published October 9, 2018. https://doi.org/10.1073/pnas.1805186115
- You have accessMountain snowpack response to different levels of warming
- From the Cover
Laurie S. Huning and Amir AghaKouchakPNAS October 23, 2018 115 (43) 10932-10937; first published October 8, 2018. https://doi.org/10.1073/pnas.1805953115
Environmental Sciences
- You have accessFaults and associated karst collapse suggest conduits for fluid flow that influence hydraulic fracturing-induced seismicityElwyn Galloway, Tyler Hauck, Hilary Corlett, Dinu Pană, and Ryan SchultzPNAS October 23, 2018 115 (43) E10003-E10012; first published October 8, 2018. https://doi.org/10.1073/pnas.1807549115
Mathematics
- You have accessA new invariant of 4-manifoldsRobion Kirby and Abigail ThompsonPNAS October 23, 2018 115 (43) 10857-10860; first published October 22, 2018. https://doi.org/10.1073/pnas.1718953115
- You have accessTrisections of 4-manifolds with boundaryNickolas A. Castro, David T. Gay, and Juanita Pinzón-CaicedoPNAS October 23, 2018 115 (43) 10861-10868; first published October 22, 2018. https://doi.org/10.1073/pnas.1717170115
- You have accessCalculating the homology and intersection form of a 4-manifold from a trisection diagramPeter Feller, Michael Klug, Trenton Schirmer, and Drew ZemkePNAS October 23, 2018 115 (43) 10869-10874; first published October 22, 2018. https://doi.org/10.1073/pnas.1717176115
- You have accessFunctoriality of group trisectionsMichael KlugPNAS October 23, 2018 115 (43) 10875-10879; first published October 22, 2018. https://doi.org/10.1073/pnas.1717167115
- You have accessBridge trisections of knotted surfaces in 4-manifoldsJeffrey Meier and Alexander ZupanPNAS October 23, 2018 115 (43) 10880-10886; first published October 22, 2018. https://doi.org/10.1073/pnas.1717171115
- You have accessCharacterizing Dehn surgeries on links via trisectionsJeffrey Meier and Alexander ZupanPNAS October 23, 2018 115 (43) 10887-10893; first published October 22, 2018. https://doi.org/10.1073/pnas.1717187115
- You have accessSimplified broken Lefschetz fibrations and trisections of 4-manifoldsR. İnanç Baykur and Osamu SaekiPNAS October 23, 2018 115 (43) 10894-10900; first published October 22, 2018. https://doi.org/10.1073/pnas.1717175115
- You have accessComputing trisections of 4-manifoldsMark Bell, Joel Hass, Joachim Hyam Rubinstein, and Stephan TillmannPNAS October 23, 2018 115 (43) 10901-10907; first published October 22, 2018. https://doi.org/10.1073/pnas.1717173115
- You have accessGeneralized trisections in all dimensionsJ. Hyam Rubinstein and Stephan TillmannPNAS October 23, 2018 115 (43) 10908-10913; first published October 22, 2018. https://doi.org/10.1073/pnas.1718961115
Physics
- You have accessTopological quantum computation based on chiral Majorana fermionsBiao Lian, Xiao-Qi Sun, Abolhassan Vaezi, Xiao-Liang Qi, and Shou-Cheng ZhangPNAS October 23, 2018 115 (43) 10938-10942; first published October 8, 2018. https://doi.org/10.1073/pnas.1810003115
- You have accessMachine learning determination of atomic dynamics at grain boundariesTristan A. Sharp, Spencer L. Thomas, Ekin D. Cubuk, Samuel S. Schoenholz, David J. Srolovitz, and Andrea J. LiuPNAS October 23, 2018 115 (43) 10943-10947; first published October 9, 2018. https://doi.org/10.1073/pnas.1807176115
- You have accessWhy large icosahedral viruses need scaffolding proteinsSiyu Li, Polly Roy, Alex Travesset, and Roya ZandiPNAS October 23, 2018 115 (43) 10971-10976; first published October 9, 2018. https://doi.org/10.1073/pnas.1807706115
Social Sciences
Anthropology
- Open AccessSalt and marine products in the Classic Maya economy from use-wear study of stone toolsHeather McKillop and Kazuo AoyamaPNAS October 23, 2018 115 (43) 10948-10952; first published October 8, 2018. https://doi.org/10.1073/pnas.1803639115
Psychological and Cognitive Sciences
- Open AccessDistinct facial expressions represent pain and pleasure across culturesChaona Chen, Carlos Crivelli, Oliver G. B. Garrod, Philippe G. Schyns, José-Miguel Fernández-Dols, and Rachael E. JackPNAS October 23, 2018 115 (43) E10013-E10021; first published October 8, 2018. https://doi.org/10.1073/pnas.1807862115
- You have accessDopaminergic basis for signaling belief updates, but not surprise, and the link to paranoiaMatthew M. Nour, Tarik Dahoun, Philipp Schwartenbeck, Rick A. Adams, Thomas H. B. FitzGerald, Christopher Coello, Matthew B. Wall, Raymond J. Dolan, and Oliver D. HowesPNAS October 23, 2018 115 (43) E10167-E10176; first published October 8, 2018. https://doi.org/10.1073/pnas.1809298115
- You have accessEmpirical evidence of mental health risks posed by climate changeNick Obradovich, Robyn Migliorini, Martin P. Paulus, and Iyad RahwanPNAS October 23, 2018 115 (43) 10953-10958; first published October 8, 2018. https://doi.org/10.1073/pnas.1801528115
Sustainability Science
- You have accessEmpirical evidence of mental health risks posed by climate changeNick Obradovich, Robyn Migliorini, Martin P. Paulus, and Iyad RahwanPNAS October 23, 2018 115 (43) 10953-10958; first published October 8, 2018. https://doi.org/10.1073/pnas.1801528115
Biological Sciences
Biochemistry
- You have accessThe structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1Kirsten M. Knecht, Olga Buzovetsky, Constanze Schneider, Dominique Thomas, Vishok Srikanth, Lars Kaderali, Florentina Tofoleanu, Krystle Reiss, Nerea Ferreirós, Gerd Geisslinger, Victor S. Batista, Xiaoyun Ji, Jindrich Cinatl Jr., Oliver T. Keppler, and Yong XiongPNAS October 23, 2018 115 (43) E10022-E10031; first published October 10, 2018. https://doi.org/10.1073/pnas.1805593115
- You have accessMolecular mechanism of activation of the immunoregulatory amidase NAAAAlexei Gorelik, Ahmad Gebai, Katalin Illes, Daniele Piomelli, and Bhushan NagarPNAS October 23, 2018 115 (43) E10032-E10040; first published October 9, 2018. https://doi.org/10.1073/pnas.1811759115
- You have accessMeiosis-specific recombinase Dmc1 is a potent inhibitor of the Srs2 antirecombinaseJ. Brooks Crickard, Kyle Kaniecki, Youngho Kwon, Patrick Sung, and Eric C. GreenePNAS October 23, 2018 115 (43) E10041-E10048; first published October 9, 2018. https://doi.org/10.1073/pnas.1810457115
- You have accessCryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1
- Inaugural Article
Yang Li, Tian-Min Fu, Alvin Lu, Kristen Witt, Jianbin Ruan, Chen Shen, and Hao WuPNAS October 23, 2018 115 (43) 10845-10852; first published October 2, 2018. https://doi.org/10.1073/pnas.1810524115See companion article:
- Profile of Hao Wu- Jan 14, 2019
Biophysics and Computational Biology
- Open AccessRandomly distributed embedding making short-term high-dimensional data predictableHuanfei Ma, Siyang Leng, Kazuyuki Aihara, Wei Lin, and Luonan ChenPNAS October 23, 2018 115 (43) E9994-E10002; first published October 8, 2018. https://doi.org/10.1073/pnas.1802987115
- Open AccessEntropic contribution to enhanced thermal stability in the thermostable P450 CYP119Zhuo Liu, Sara Lemmonds, Juan Huang, Madhusudan Tyagi, Liang Hong, and Nitin JainPNAS October 23, 2018 115 (43) E10049-E10058; first published October 8, 2018. https://doi.org/10.1073/pnas.1807473115
- You have accessSwi5–Sfr1 stimulates Rad51 recombinase filament assembly by modulating Rad51 dissociationChih-Hao Lu, Hsin-Yi Yeh, Guan-Chin Su, Kentaro Ito, Yumiko Kurokawa, Hiroshi Iwasaki, Peter Chi, and Hung-Wen LiPNAS October 23, 2018 115 (43) E10059-E10068; first published October 8, 2018. https://doi.org/10.1073/pnas.1812753115
- Open AccessNonproteinogenic deep mutational scanning of linear and cyclic peptidesJoseph M. Rogers, Toby Passioura, and Hiroaki SugaPNAS October 23, 2018 115 (43) 10959-10964; first published October 9, 2018. https://doi.org/10.1073/pnas.1809901115
- You have accessProtein shape modulates crowding effectsAlex J. Guseman, Gerardo M. Perez Goncalves, Shannon L. Speer, Gregory B. Young, and Gary J. PielakPNAS October 23, 2018 115 (43) 10965-10970; first published October 9, 2018. https://doi.org/10.1073/pnas.1810054115
- You have accessWhy large icosahedral viruses need scaffolding proteinsSiyu Li, Polly Roy, Alex Travesset, and Roya ZandiPNAS October 23, 2018 115 (43) 10971-10976; first published October 9, 2018. https://doi.org/10.1073/pnas.1807706115
Cell Biology
- Open AccessmTOR inhibitors lower an intrinsic barrier to virus infection mediated by IFITM3Guoli Shi, Stosh Ozog, Bruce E. Torbett, and Alex A. ComptonPNAS October 23, 2018 115 (43) E10069-E10078; first published October 9, 2018. https://doi.org/10.1073/pnas.1811892115
- You have accessMitosis-specific MRN complex promotes a mitotic signaling cascade to regulate spindle dynamics and chromosome segregationRan Xu, Yixi Xu, Wei Huo, Zhicong Lv, Jingsong Yuan, Shaokai Ning, Qingsong Wang, Mei Hou, Ge Gao, Jianguo Ji, Junjie Chen, Rong Guo, and Dongyi XuPNAS October 23, 2018 115 (43) E10079-E10088; first published October 8, 2018. https://doi.org/10.1073/pnas.1806665115
- You have accessXBP1s activation can globally remodel N-glycan structure distribution patternsMadeline Y. Wong, Kenny Chen, Aristotelis Antonopoulos, Brian T. Kasper, Mahender B. Dewal, Rebecca J. Taylor, Charles A. Whittaker, Pyae P. Hein, Anne Dell, Joseph C. Genereux, Stuart M. Haslam, Lara K. Mahal, and Matthew D. ShouldersPNAS October 23, 2018 115 (43) E10089-E10098; first published October 10, 2018. https://doi.org/10.1073/pnas.1805425115
- Open AccessNoncanonical autophagy at ER exit sites regulates procollagen turnoverShakib Omari, Elena Makareeva, Anna Roberts-Pilgrim, Lynn Mirigian, Michal Jarnik, Carolyn Ott, Jennifer Lippincott-Schwartz, and Sergey LeikinPNAS October 23, 2018 115 (43) E10099-E10108; first published October 4, 2018. https://doi.org/10.1073/pnas.1814552115
- You have accessCryo-ET reveals the macromolecular reorganization of S. pombe mitotic chromosomes in vivoShujun Cai, Chen Chen, Zhi Yang Tan, Yinyi Huang, Jian Shi, and Lu GanPNAS October 23, 2018 115 (43) 10977-10982; first published October 8, 2018. https://doi.org/10.1073/pnas.1720476115
- You have accessSUMO protease SENP1 deSUMOylates and stabilizes c-MycXiao-Xin Sun, Yingxiao Chen, Yulong Su, Xiaoyan Wang, Krishna Mohan Chauhan, Juan Liang, Colin J. Daniel, Rosalie C. Sears, and Mu-Shui DaiPNAS October 23, 2018 115 (43) 10983-10988; first published October 10, 2018. https://doi.org/10.1073/pnas.1802932115
Ecology
- Open AccessChanges in temperature alter the relationship between biodiversity and ecosystem functioningFrancisca C. García, Elvire Bestion, Ruth Warfield, and Gabriel Yvon-DurocherPNAS October 23, 2018 115 (43) 10989-10994; first published October 8, 2018. https://doi.org/10.1073/pnas.1805518115
- You have accessMagnetic map in nonanadromous Atlantic salmonMichelle M. Scanlan, Nathan F. Putman, Amanda M. Pollock, and David L. G. NoakesPNAS October 23, 2018 115 (43) 10995-10999; first published October 8, 2018. https://doi.org/10.1073/pnas.1807705115
Environmental Sciences
- Open AccessNative-state imaging of calcifying and noncalcifying microalgae reveals similarities in their calcium storage organellesAssaf Gal, Andrea Sorrentino, Keren Kahil, Eva Pereiro, Damien Faivre, and André ScheffelPNAS October 23, 2018 115 (43) 11000-11005; first published October 4, 2018. https://doi.org/10.1073/pnas.1804139115
Evolution
- Open AccessSelection and gene flow shape genomic islands that control floral guidesHugo Tavares, Annabel Whibley, David L. Field, Desmond Bradley, Matthew Couchman, Lucy Copsey, Joane Elleouet, Monique Burrus, Christophe Andalo, Miaomiao Li, Qun Li, Yongbiao Xue, Alexandra B. Rebocho, Nicolas H. Barton, and Enrico CoenPNAS October 23, 2018 115 (43) 11006-11011; first published October 8, 2018. https://doi.org/10.1073/pnas.1801832115
- Open AccessWhole-genome comparison of endogenous retrovirus segregation across wild and domestic host species populationsSalvador Daniel Rivas-Carrillo, Mats E. Pettersson, Carl-Johan Rubin, and Patric JernPNAS October 23, 2018 115 (43) 11012-11017; first published October 8, 2018. https://doi.org/10.1073/pnas.1815056115
Genetics
- You have accessHuman leukemia mutations corrupt but do not abrogate GATA-2 functionKoichi R. Katsumura, Charu Mehta, Kyle J. Hewitt, Alexandra A. Soukup, Isabela Fraga de Andrade, Erik A. Ranheim, Kirby D. Johnson, and Emery H. BresnickPNAS October 23, 2018 115 (43) E10109-E10118; first published October 9, 2018. https://doi.org/10.1073/pnas.1813015115
- Open AccessGenetic variation in the SIM1 locus is associated with erectile dysfunction
- From the Cover
Eric Jorgenson, Navneet Matharu, Melody R. Palmer, Jie Yin, Jun Shan, Thomas J. Hoffmann, Khanh K. Thai, Xujia Zhou, James M. Hotaling, Gail P. Jarvik, Nadav Ahituv, Hunter Wessells, and Stephen K. Van Den EedenPNAS October 23, 2018 115 (43) 11018-11023; first published October 8, 2018. https://doi.org/10.1073/pnas.1809872115See companion article:
- You have accessHuman mitochondrial degradosome prevents harmful mitochondrial R loops and mitochondrial genome instabilitySonia Silva, Lola P. Camino, and Andrés AguileraPNAS October 23, 2018 115 (43) 11024-11029; first published October 9, 2018. https://doi.org/10.1073/pnas.1807258115
- You have accessFunctional and evolutionary characterization of a secondary metabolite gene cluster in budding yeastsDavid J. Krause, Jacek Kominek, Dana A. Opulente, Xing-Xing Shen, Xiaofan Zhou, Quinn K. Langdon, Jeremy DeVirgilio, Amanda Beth Hulfachor, Cletus P. Kurtzman, Antonis Rokas, and Chris Todd HittingerPNAS October 23, 2018 115 (43) 11030-11035; first published October 8, 2018. https://doi.org/10.1073/pnas.1806268115
Immunology and Inflammation
- Open AccessRegnase-1 controls colon epithelial regeneration via regulation of mTOR and purine metabolismYasuharu Nagahama, Mayuko Shimoda, Guoliang Mao, Shailendra Kumar Singh, Yuuki Kozakai, Xin Sun, Daisuke Motooka, Shota Nakamura, Hiroki Tanaka, Takashi Satoh, Kazuhiko Maeda, and Shizuo AkiraPNAS October 23, 2018 115 (43) 11036-11041; first published October 8, 2018. https://doi.org/10.1073/pnas.1809575115
- You have accessGlucose metabolism mediates disease tolerance in cerebral malariaAndrew Wang, Sarah C. Huen, Harding H. Luan, Kelly Baker, Henry Rinder, Carmen J. Booth, and Ruslan MedzhitovPNAS October 23, 2018 115 (43) 11042-11047; first published October 5, 2018. https://doi.org/10.1073/pnas.1806376115
- You have accessToxicity of an Fc-engineered anti-CD40 antibody is abrogated by intratumoral injection and results in durable antitumor immunityDavid A. Knorr, Rony Dahan, and Jeffrey V. RavetchPNAS October 23, 2018 115 (43) 11048-11053; first published October 8, 2018. https://doi.org/10.1073/pnas.1810566115
- You have accessC-type lectin receptor LSECtin-mediated apoptotic cell clearance by macrophages directs intestinal repair in experimental colitisZaopeng Yang, Qian Li, Xin Wang, Xuepei Jiang, Dianyuan Zhao, Xin Lin, Fuchu He, and Li TangPNAS October 23, 2018 115 (43) 11054-11059; first published October 9, 2018. https://doi.org/10.1073/pnas.1804094115
Medical Sciences
- Open AccessDifferential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti–PD-L1)Marcin Kowanetz, Wei Zou, Scott N. Gettinger, Hartmut Koeppen, Mark Kockx, Peter Schmid, Edward E. Kadel III, Ignacio Wistuba, Jamie Chaft, Naiyer A. Rizvi, David R. Spigel, Alexander Spira, Fred R. Hirsch, Victor Cohen, Dustin Smith, Zach Boyd, Natasha Miley, Susan Flynn, Vincent Leveque, David S. Shames, Marcus Ballinger, Simonetta Mocci, Geetha Shankar, Roel Funke, Garret Hampton, Alan Sandler, Lukas Amler, Ira Mellman, Daniel S. Chen, and Priti S. HegdePNAS October 23, 2018 115 (43) E10119-E10126; first published October 8, 2018. https://doi.org/10.1073/pnas.1802166115
- Open AccessiNOS promotes CD24+CD133+ liver cancer stem cell phenotype through a TACE/ADAM17-dependent Notch signaling pathwayRonghua Wang, Yawen Li, Allan Tsung, Hai Huang, Qiang Du, Muqing Yang, Meihong Deng, Si Xiong, Xiju Wang, Liyong Zhang, David A. Geller, Bin Cheng, and Timothy R. BilliarPNAS October 23, 2018 115 (43) E10127-E10136; first published October 8, 2018. https://doi.org/10.1073/pnas.1722100115
- You have accessHistone methylation regulator PTIP is required to maintain normal and leukemic bone marrow nichesProsun Das, Kylee J. Veazey, Hieu T. Van, Saakshi Kaushik, Kevin Lin, Yue Lu, Masaru Ishii, Junichi Kikuta, Kai Ge, Andre Nussenzweig, and Margarida A. SantosPNAS October 23, 2018 115 (43) E10137-E10146; first published October 8, 2018. https://doi.org/10.1073/pnas.1806019115
- Open AccessMetastatic growth instructed by neutrophil-derived transferrinWei Liang, Qin Li, and Napoleone FerraraPNAS October 23, 2018 115 (43) 11060-11065; first published October 9, 2018. https://doi.org/10.1073/pnas.1811717115
- You have accessReducing dynamin 2 (DNM2) rescues DNM2-related dominant centronuclear myopathySuzie Buono, Jacob A. Ross, Hichem Tasfaout, Yotam Levy, Christine Kretz, Leighla Tayefeh, John Matson, Shuling Guo, Pascal Kessler, Brett P. Monia, Marc Bitoun, Julien Ochala, Jocelyn Laporte, and Belinda S. CowlingPNAS October 23, 2018 115 (43) 11066-11071; first published October 5, 2018. https://doi.org/10.1073/pnas.1808170115
Microbiology
- You have accessMmpL8MAB controls Mycobacterium abscessus virulence and production of a previously unknown glycolipid familyViolaine Dubois, Albertus Viljoen, Laura Laencina, Vincent Le Moigne, Audrey Bernut, Faustine Dubar, Mickaël Blaise, Jean-Louis Gaillard, Yann Guérardel, Laurent Kremer, Jean-Louis Herrmann, and Fabienne Girard-MisguichPNAS October 23, 2018 115 (43) E10147-E10156; first published October 9, 2018. https://doi.org/10.1073/pnas.1812984115
- Open AccessInterplay between coronavirus, a cytoplasmic RNA virus, and nonsense-mediated mRNA decay pathwayMasami Wada, Kumari G. Lokugamage, Keisuke Nakagawa, Krishna Narayanan, and Shinji MakinoPNAS October 23, 2018 115 (43) E10157-E10166; first published October 8, 2018. https://doi.org/10.1073/pnas.1811675115
- You have accessElongation factor P is required to maintain proteome homeostasis at high growth rateRodney Tollerson II, Anne Witzky, and Michael IbbaPNAS October 23, 2018 115 (43) 11072-11077; first published October 8, 2018. https://doi.org/10.1073/pnas.1812025115
Neuroscience
- You have accessDopaminergic basis for signaling belief updates, but not surprise, and the link to paranoiaMatthew M. Nour, Tarik Dahoun, Philipp Schwartenbeck, Rick A. Adams, Thomas H. B. FitzGerald, Christopher Coello, Matthew B. Wall, Raymond J. Dolan, and Oliver D. HowesPNAS October 23, 2018 115 (43) E10167-E10176; first published October 8, 2018. https://doi.org/10.1073/pnas.1809298115
- Open AccessActivity-dependent bulk endocytosis proteome reveals a key presynaptic role for the monomeric GTPase Rab11A. C. Kokotos, J. Peltier, E. C. Davenport, M. Trost, and M. A. CousinPNAS October 23, 2018 115 (43) E10177-E10186; first published October 9, 2018. https://doi.org/10.1073/pnas.1809189115
- Open AccessChronic social stress-induced hyperglycemia in mice couples individual stress susceptibility to impaired spatial memoryMichael A. van der Kooij, Tanja Jene, Giulia Treccani, Isabelle Miederer, Annika Hasch, Nadine Voelxen, Stefan Walenta, and Marianne B. MüllerPNAS October 23, 2018 115 (43) E10187-E10196; first published October 9, 2018. https://doi.org/10.1073/pnas.1804412115
- Open AccessLong noncoding RNA GM12371 acts as a transcriptional regulator of synapse functionBindu L. Raveendra, Supriya Swarnkar, Yosef Avchalumov, Xin-An Liu, Eddie Grinman, Kerriann Badal, Adrian Reich, Bruce D. Pascal, and Sathyanarayanan V. PuthanveettilPNAS October 23, 2018 115 (43) E10197-E10205; first published October 8, 2018. https://doi.org/10.1073/pnas.1722587115
- You have accessThe brain’s hemodynamic response function rapidly changes under acute psychosocial stress in association with genetic and endocrine stress response markers
- From the Cover
Immanuel G. Elbau, Benedikt Brücklmeier, Manfred Uhr, Janine Arloth, Darina Czamara, Victor I. Spoormaker, Michael Czisch, Klaas Enno Stephan, Elisabeth B. Binder, and Philipp G. SämannPNAS October 23, 2018 115 (43) E10206-E10215; first published September 10, 2018. https://doi.org/10.1073/pnas.1804340115See companion article:
- Stress response regulation and the hemodynamic response- Oct 11, 2018
- You have accessDSCAM promotes self-avoidance in the developing mouse retina by masking the functions of cadherin superfamily membersAndrew M. Garrett, Andre Khalil, David O. Walton, and Robert W. BurgessPNAS October 23, 2018 115 (43) E10216-E10224; first published October 8, 2018. https://doi.org/10.1073/pnas.1809430115
- You have accessMRI-based assessment of function and dysfunction in myelinated axonsWilliam M. Spees, Tsen-Hsuan Lin, Peng Sun, Chunyu Song, Ajit George, Sam E. Gary, Hsin-Chieh Yang, and Sheng-Kwei SongPNAS October 23, 2018 115 (43) E10225-E10234; first published October 8, 2018. https://doi.org/10.1073/pnas.1801788115
- You have accessCbln2 and Cbln4 are expressed in distinct medial habenula-interpeduncular projections and contribute to different behavioral outputsErica Seigneur, Jai S. Polepalli, and Thomas C. SüdhofPNAS October 23, 2018 115 (43) E10235-E10244; first published October 4, 2018. https://doi.org/10.1073/pnas.1811086115
- You have accessYin-and-yang bifurcation of opioidergic circuits for descending analgesia at the midbrain of the mouseJong-Hyun Kim, Gireesh Gangadharan, Junweon Byun, Eui-Ju Choi, C. Justin Lee, and Hee-Sup ShinPNAS October 23, 2018 115 (43) 11078-11083; first published October 8, 2018. https://doi.org/10.1073/pnas.1806082115
Pharmacology
- Open Accessp38α MAPK signaling drives pharmacologically reversible brain and gastrointestinal phenotypes in the SERT Ala56 mouseMatthew J. Robson, Meagan A. Quinlan, Kara Gross Margolis, Paula A. Gajewski-Kurdziel, Jeremy Veenstra-VanderWeele, Michael D. Gershon, D. Martin Watterson, and Randy D. BlakelyPNAS October 23, 2018 115 (43) E10245-E10254; first published October 8, 2018. https://doi.org/10.1073/pnas.1809137115
- You have accessTranslating biased signaling in the ghrelin receptor system into differential in vivo functionsFranziska Mende, Cecilie Hundahl, Bianca Plouffe, Louise Julie Skov, Bjørn Sivertsen, Andreas Nygaard Madsen, Michael Lückmann, Thi Ai Diep, Stefan Offermanns, Thomas Michael Frimurer, Michel Bouvier, and Birgitte HolstPNAS October 23, 2018 115 (43) E10255-E10264; first published October 9, 2018. https://doi.org/10.1073/pnas.1804003115
Plant Biology
- You have accessQuantitative and functional posttranslational modification proteomics reveals that TREPH1 plays a role in plant touch-delayed boltingKai Wang, Zhu Yang, Dongjin Qing, Feng Ren, Shichang Liu, Qingsong Zheng, Jun Liu, Weiping Zhang, Chen Dai, Madeline Wu, E. Wassim Chehab, Janet Braam, and Ning LiPNAS October 23, 2018 115 (43) E10265-E10274; first published October 5, 2018. https://doi.org/10.1073/pnas.1814006115
Psychological and Cognitive Sciences
- You have accessNeural reactivation in parietal cortex enhances memory for episodically linked informationTanya R. Jonker, Halle Dimsdale-Zucker, Maureen Ritchey, Alex Clarke, and Charan RanganathPNAS October 23, 2018 115 (43) 11084-11089; first published October 8, 2018. https://doi.org/10.1073/pnas.1800006115
- You have accessHumans incorporate attention-dependent uncertainty into perceptual decisions and confidenceRachel N. Denison, William T. Adler, Marisa Carrasco, and Wei Ji MaPNAS October 23, 2018 115 (43) 11090-11095; first published October 8, 2018. https://doi.org/10.1073/pnas.1717720115
Sustainability Science
- Open AccessBottom trawl fishing footprints on the world’s continental shelvesRicardo O. Amoroso, C. Roland Pitcher, Adriaan D. Rijnsdorp, Robert A. McConnaughey, Ana M. Parma, Petri Suuronen, Ole R. Eigaard, Francois Bastardie, Niels T. Hintzen, Franziska Althaus, Susan Jane Baird, Jenny Black, Lene Buhl-Mortensen, Alexander B. Campbell, Rui Catarino, Jeremy Collie, James H. Cowan Jr., Deon Durholtz, Nadia Engstrom, Tracey P. Fairweather, Heino O. Fock, Richard Ford, Patricio A. Gálvez, Hans Gerritsen, María Eva Góngora, Jessica A. González, Jan G. Hiddink, Kathryn M. Hughes, Steven S. Intelmann, Chris Jenkins, Patrik Jonsson, Paulus Kainge, Mervi Kangas, Johannes N. Kathena, Stefanos Kavadas, Rob W. Leslie, Steve G. Lewis, Mathieu Lundy, David Makin, Julie Martin, Tessa Mazor, Genoveva Gonzalez-Mirelis, Stephen J. Newman, Nadia Papadopoulou, Paulette E. Posen, Wayne Rochester, Tommaso Russo, Antonello Sala, Jayson M. Semmens, Cristina Silva, Angelo Tsolos, Bart Vanelslander, Corey B. Wakefield, Brent A. Wood, Ray Hilborn, Michel J. Kaiser, and Simon JenningsPNAS October 23, 2018 115 (43) E10275-E10282; first published October 8, 2018. https://doi.org/10.1073/pnas.1802379115
Systems Biology
- You have accessCharacterizing posttranslational modifications in prokaryotic metabolism using a multiscale workflowElizabeth Brunk, Roger L. Chang, Jing Xia, Hooman Hefzi, James T. Yurkovich, Donghyuk Kim, Evan Buckmiller, Harris H. Wang, Byung-Kwan Cho, Chen Yang, Bernhard O. Palsson, George M. Church, and Nathan E. LewisPNAS October 23, 2018 115 (43) 11096-11101; first published October 9, 2018. https://doi.org/10.1073/pnas.1811971115
Corrections (Online Only)
- You have accessCorrection for Kneller, Franck–Condon picture of incoherent neutron scatteringPNAS October 23, 2018 115 (43) E10283; first published October 15, 2018. https://doi.org/10.1073/pnas.1816793115
- You have accessCorrection for Liao et al., Metal–insulator-transition engineering by modulation tilt-control in perovskite nickelates for room temperature optical switchingPNAS October 23, 2018 115 (43) E10284; first published October 15, 2018. https://doi.org/10.1073/pnas.1816794115
- You have accessCorrection for Baldwin and Mussweiler, The culture of social comparisonPNAS October 23, 2018 115 (43) E10285; first published October 15, 2018. https://doi.org/10.1073/pnas.1816586115
- You have accessCorrection for Li et al., Mutually inhibitory Ras-PI(3,4)P2 feedback loops mediate cell migrationPNAS October 23, 2018 115 (43) E10286; first published October 15, 2018. https://doi.org/10.1073/pnas.1816155115
Commentaries
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