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Table of Contents

October 23, 2018; vol. 115 no. 43

This Week in PNAS

  • You have access
    In This Issue
    PNAS October 23, 2018 115 (43) 10817-10819; https://doi.org/10.1073/iti4318115

Opinion

Leading scientists discuss current issues.
  • You have access
    Opinion: Advocating for science progress as a human right
    • Front Matter
    S. Porsdam Mann, Y. Donders, C. Mitchell, V. J. Bradley, M. F. Chou, M. Mann, G. Church, and H. Porsdam
    PNAS October 23, 2018 115 (43) 10820-10823; https://doi.org/10.1073/pnas.1816320115

Commentaries

  • You have access
    Navigating genetic diversity by painting the bacteria red
    Claire M. Palmer and Hal S. Alper
    PNAS October 23, 2018 115 (43) 10824-10826; first published October 11, 2018. https://doi.org/10.1073/pnas.1815763115

    See companion article:

    • Repurposing type III polyketide synthase as a malonyl-CoA biosensor for metabolic engineering in bacteria
      - Sep 19, 2018
  • You have access
    Stress response regulation and the hemodynamic response
    Katharine Dunlop and Conor Liston
    PNAS October 23, 2018 115 (43) 10827-10829; first published October 11, 2018. https://doi.org/10.1073/pnas.1814592115

    See companion article:

    • The brain’s hemodynamic response function rapidly changes under acute psychosocial stress in association with genetic and endocrine stress response markers
      - Sep 10, 2018

PNAS Plus Significance Statements

Brief statements written by the authors about the significance of their papers.
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    PNAS Plus Significance Statements
    PNAS October 23, 2018 115 (43) 10830-10835; https://doi.org/10.1073/pnas.ss11543

Perspective

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    Prolonging healthy aging: Longevity vitamins and proteins
    Bruce N. Ames
    PNAS October 23, 2018 115 (43) 10836-10844; first published October 15, 2018. https://doi.org/10.1073/pnas.1809045115

Trisections of Smooth Manifolds Special Feature (Free Online)

  • Introduction

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      Trisections of 4-manifolds
      • From the Cover
      Robion Kirby
      PNAS October 23, 2018 115 (43) 10853-10856; first published October 22, 2018. https://doi.org/10.1073/pnas.1717166115
  • Research Articles

    • You have access
      A new invariant of 4-manifolds
      Robion Kirby and Abigail Thompson
      PNAS October 23, 2018 115 (43) 10857-10860; first published October 22, 2018. https://doi.org/10.1073/pnas.1718953115
    • You have access
      Trisections of 4-manifolds with boundary
      Nickolas A. Castro, David T. Gay, and Juanita Pinzón-Caicedo
      PNAS October 23, 2018 115 (43) 10861-10868; first published October 22, 2018. https://doi.org/10.1073/pnas.1717170115
    • You have access
      Calculating the homology and intersection form of a 4-manifold from a trisection diagram
      Peter Feller, Michael Klug, Trenton Schirmer, and Drew Zemke
      PNAS October 23, 2018 115 (43) 10869-10874; first published October 22, 2018. https://doi.org/10.1073/pnas.1717176115
    • You have access
      Functoriality of group trisections
      Michael Klug
      PNAS October 23, 2018 115 (43) 10875-10879; first published October 22, 2018. https://doi.org/10.1073/pnas.1717167115
    • You have access
      Bridge trisections of knotted surfaces in 4-manifolds
      Jeffrey Meier and Alexander Zupan
      PNAS October 23, 2018 115 (43) 10880-10886; first published October 22, 2018. https://doi.org/10.1073/pnas.1717171115
    • You have access
      Characterizing Dehn surgeries on links via trisections
      Jeffrey Meier and Alexander Zupan
      PNAS October 23, 2018 115 (43) 10887-10893; first published October 22, 2018. https://doi.org/10.1073/pnas.1717187115
    • You have access
      Simplified broken Lefschetz fibrations and trisections of 4-manifolds
      R. İnanç Baykur and Osamu Saeki
      PNAS October 23, 2018 115 (43) 10894-10900; first published October 22, 2018. https://doi.org/10.1073/pnas.1717175115
    • You have access
      Computing trisections of 4-manifolds
      Mark Bell, Joel Hass, Joachim Hyam Rubinstein, and Stephan Tillmann
      PNAS October 23, 2018 115 (43) 10901-10907; first published October 22, 2018. https://doi.org/10.1073/pnas.1717173115
    • You have access
      Generalized trisections in all dimensions
      J. Hyam Rubinstein and Stephan Tillmann
      PNAS October 23, 2018 115 (43) 10908-10913; first published October 22, 2018. https://doi.org/10.1073/pnas.1718961115

Physical Sciences

  • Applied Mathematics

    • Open Access
      Randomly distributed embedding making short-term high-dimensional data predictable
      Huanfei Ma, Siyang Leng, Kazuyuki Aihara, Wei Lin, and Luonan Chen
      PNAS October 23, 2018 115 (43) E9994-E10002; first published October 8, 2018. https://doi.org/10.1073/pnas.1802987115
  • Applied Physical Sciences

    • Open Access
      Verifying Larché–Cahn elasticity, a milestone of 20th-century thermodynamics
      Shan Shi, Jürgen Markmann, and Jörg Weissmüller
      PNAS October 23, 2018 115 (43) 10914-10919; first published October 5, 2018. https://doi.org/10.1073/pnas.1809355115
  • Chemistry

    • Open Access
      Nonproteinogenic deep mutational scanning of linear and cyclic peptides
      Joseph M. Rogers, Toby Passioura, and Hiroaki Suga
      PNAS October 23, 2018 115 (43) 10959-10964; first published October 9, 2018. https://doi.org/10.1073/pnas.1809901115
    • You have access
      Protein shape modulates crowding effects
      Alex J. Guseman, Gerardo M. Perez Goncalves, Shannon L. Speer, Gregory B. Young, and Gary J. Pielak
      PNAS October 23, 2018 115 (43) 10965-10970; first published October 9, 2018. https://doi.org/10.1073/pnas.1810054115
    • Open Access
      Native-state imaging of calcifying and noncalcifying microalgae reveals similarities in their calcium storage organelles
      Assaf Gal, Andrea Sorrentino, Keren Kahil, Eva Pereiro, Damien Faivre, and André Scheffel
      PNAS October 23, 2018 115 (43) 11000-11005; first published October 4, 2018. https://doi.org/10.1073/pnas.1804139115
  • Earth, Atmospheric, and Planetary Sciences

    • Open Access
      Volatile loss following cooling and accretion of the Moon revealed by chromium isotopes
      Paolo A. Sossi, Frédéric Moynier, and Kirsten van Zuilen
      PNAS October 23, 2018 115 (43) 10920-10925; first published October 8, 2018. https://doi.org/10.1073/pnas.1809060115
    • Open Access
      Redox-dependent niche differentiation provides evidence for multiple bacterial sources of glycerol tetraether lipids in lakes
      Yuki Weber, Jaap S. Sinninghe Damsté, Jakob Zopfi, Cindy De Jonge, Adrian Gilli, Carsten J. Schubert, Fabio Lepori, Moritz F. Lehmann, and Helge Niemann
      PNAS October 23, 2018 115 (43) 10926-10931; first published October 9, 2018. https://doi.org/10.1073/pnas.1805186115
    • You have access
      Mountain snowpack response to different levels of warming
      • From the Cover
      Laurie S. Huning and Amir AghaKouchak
      PNAS October 23, 2018 115 (43) 10932-10937; first published October 8, 2018. https://doi.org/10.1073/pnas.1805953115
  • Environmental Sciences

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      Faults and associated karst collapse suggest conduits for fluid flow that influence hydraulic fracturing-induced seismicity
      Elwyn Galloway, Tyler Hauck, Hilary Corlett, Dinu Pană, and Ryan Schultz
      PNAS October 23, 2018 115 (43) E10003-E10012; first published October 8, 2018. https://doi.org/10.1073/pnas.1807549115
  • Mathematics

    • You have access
      A new invariant of 4-manifolds
      Robion Kirby and Abigail Thompson
      PNAS October 23, 2018 115 (43) 10857-10860; first published October 22, 2018. https://doi.org/10.1073/pnas.1718953115
    • You have access
      Trisections of 4-manifolds with boundary
      Nickolas A. Castro, David T. Gay, and Juanita Pinzón-Caicedo
      PNAS October 23, 2018 115 (43) 10861-10868; first published October 22, 2018. https://doi.org/10.1073/pnas.1717170115
    • You have access
      Calculating the homology and intersection form of a 4-manifold from a trisection diagram
      Peter Feller, Michael Klug, Trenton Schirmer, and Drew Zemke
      PNAS October 23, 2018 115 (43) 10869-10874; first published October 22, 2018. https://doi.org/10.1073/pnas.1717176115
    • You have access
      Functoriality of group trisections
      Michael Klug
      PNAS October 23, 2018 115 (43) 10875-10879; first published October 22, 2018. https://doi.org/10.1073/pnas.1717167115
    • You have access
      Bridge trisections of knotted surfaces in 4-manifolds
      Jeffrey Meier and Alexander Zupan
      PNAS October 23, 2018 115 (43) 10880-10886; first published October 22, 2018. https://doi.org/10.1073/pnas.1717171115
    • You have access
      Characterizing Dehn surgeries on links via trisections
      Jeffrey Meier and Alexander Zupan
      PNAS October 23, 2018 115 (43) 10887-10893; first published October 22, 2018. https://doi.org/10.1073/pnas.1717187115
    • You have access
      Simplified broken Lefschetz fibrations and trisections of 4-manifolds
      R. İnanç Baykur and Osamu Saeki
      PNAS October 23, 2018 115 (43) 10894-10900; first published October 22, 2018. https://doi.org/10.1073/pnas.1717175115
    • You have access
      Computing trisections of 4-manifolds
      Mark Bell, Joel Hass, Joachim Hyam Rubinstein, and Stephan Tillmann
      PNAS October 23, 2018 115 (43) 10901-10907; first published October 22, 2018. https://doi.org/10.1073/pnas.1717173115
    • You have access
      Generalized trisections in all dimensions
      J. Hyam Rubinstein and Stephan Tillmann
      PNAS October 23, 2018 115 (43) 10908-10913; first published October 22, 2018. https://doi.org/10.1073/pnas.1718961115
  • Physics

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      Topological quantum computation based on chiral Majorana fermions
      Biao Lian, Xiao-Qi Sun, Abolhassan Vaezi, Xiao-Liang Qi, and Shou-Cheng Zhang
      PNAS October 23, 2018 115 (43) 10938-10942; first published October 8, 2018. https://doi.org/10.1073/pnas.1810003115
    • You have access
      Machine learning determination of atomic dynamics at grain boundaries
      Tristan A. Sharp, Spencer L. Thomas, Ekin D. Cubuk, Samuel S. Schoenholz, David J. Srolovitz, and Andrea J. Liu
      PNAS October 23, 2018 115 (43) 10943-10947; first published October 9, 2018. https://doi.org/10.1073/pnas.1807176115
    • You have access
      Why large icosahedral viruses need scaffolding proteins
      Siyu Li, Polly Roy, Alex Travesset, and Roya Zandi
      PNAS October 23, 2018 115 (43) 10971-10976; first published October 9, 2018. https://doi.org/10.1073/pnas.1807706115

Social Sciences

  • Anthropology

    • Open Access
      Salt and marine products in the Classic Maya economy from use-wear study of stone tools
      Heather McKillop and Kazuo Aoyama
      PNAS October 23, 2018 115 (43) 10948-10952; first published October 8, 2018. https://doi.org/10.1073/pnas.1803639115
  • Psychological and Cognitive Sciences

    • Open Access
      Distinct facial expressions represent pain and pleasure across cultures
      Chaona Chen, Carlos Crivelli, Oliver G. B. Garrod, Philippe G. Schyns, José-Miguel Fernández-Dols, and Rachael E. Jack
      PNAS October 23, 2018 115 (43) E10013-E10021; first published October 8, 2018. https://doi.org/10.1073/pnas.1807862115
    • You have access
      Dopaminergic basis for signaling belief updates, but not surprise, and the link to paranoia
      Matthew M. Nour, Tarik Dahoun, Philipp Schwartenbeck, Rick A. Adams, Thomas H. B. FitzGerald, Christopher Coello, Matthew B. Wall, Raymond J. Dolan, and Oliver D. Howes
      PNAS October 23, 2018 115 (43) E10167-E10176; first published October 8, 2018. https://doi.org/10.1073/pnas.1809298115
    • You have access
      Empirical evidence of mental health risks posed by climate change
      Nick Obradovich, Robyn Migliorini, Martin P. Paulus, and Iyad Rahwan
      PNAS October 23, 2018 115 (43) 10953-10958; first published October 8, 2018. https://doi.org/10.1073/pnas.1801528115
  • Sustainability Science

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      Empirical evidence of mental health risks posed by climate change
      Nick Obradovich, Robyn Migliorini, Martin P. Paulus, and Iyad Rahwan
      PNAS October 23, 2018 115 (43) 10953-10958; first published October 8, 2018. https://doi.org/10.1073/pnas.1801528115

Biological Sciences

  • Biochemistry

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      The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1
      Kirsten M. Knecht, Olga Buzovetsky, Constanze Schneider, Dominique Thomas, Vishok Srikanth, Lars Kaderali, Florentina Tofoleanu, Krystle Reiss, Nerea Ferreirós, Gerd Geisslinger, Victor S. Batista, Xiaoyun Ji, Jindrich Cinatl Jr., Oliver T. Keppler, and Yong Xiong
      PNAS October 23, 2018 115 (43) E10022-E10031; first published October 10, 2018. https://doi.org/10.1073/pnas.1805593115
    • You have access
      Molecular mechanism of activation of the immunoregulatory amidase NAAA
      Alexei Gorelik, Ahmad Gebai, Katalin Illes, Daniele Piomelli, and Bhushan Nagar
      PNAS October 23, 2018 115 (43) E10032-E10040; first published October 9, 2018. https://doi.org/10.1073/pnas.1811759115
    • You have access
      Meiosis-specific recombinase Dmc1 is a potent inhibitor of the Srs2 antirecombinase
      J. Brooks Crickard, Kyle Kaniecki, Youngho Kwon, Patrick Sung, and Eric C. Greene
      PNAS October 23, 2018 115 (43) E10041-E10048; first published October 9, 2018. https://doi.org/10.1073/pnas.1810457115
    • You have access
      Cryo-EM structures of ASC and NLRC4 CARD filaments reveal a unified mechanism of nucleation and activation of caspase-1
      • Inaugural Article
      Yang Li, Tian-Min Fu, Alvin Lu, Kristen Witt, Jianbin Ruan, Chen Shen, and Hao Wu
      PNAS October 23, 2018 115 (43) 10845-10852; first published October 2, 2018. https://doi.org/10.1073/pnas.1810524115

      See companion article:

      • Profile of Hao Wu
        - Jan 14, 2019
  • Biophysics and Computational Biology

    • Open Access
      Randomly distributed embedding making short-term high-dimensional data predictable
      Huanfei Ma, Siyang Leng, Kazuyuki Aihara, Wei Lin, and Luonan Chen
      PNAS October 23, 2018 115 (43) E9994-E10002; first published October 8, 2018. https://doi.org/10.1073/pnas.1802987115
    • Open Access
      Entropic contribution to enhanced thermal stability in the thermostable P450 CYP119
      Zhuo Liu, Sara Lemmonds, Juan Huang, Madhusudan Tyagi, Liang Hong, and Nitin Jain
      PNAS October 23, 2018 115 (43) E10049-E10058; first published October 8, 2018. https://doi.org/10.1073/pnas.1807473115
    • You have access
      Swi5–Sfr1 stimulates Rad51 recombinase filament assembly by modulating Rad51 dissociation
      Chih-Hao Lu, Hsin-Yi Yeh, Guan-Chin Su, Kentaro Ito, Yumiko Kurokawa, Hiroshi Iwasaki, Peter Chi, and Hung-Wen Li
      PNAS October 23, 2018 115 (43) E10059-E10068; first published October 8, 2018. https://doi.org/10.1073/pnas.1812753115
    • Open Access
      Nonproteinogenic deep mutational scanning of linear and cyclic peptides
      Joseph M. Rogers, Toby Passioura, and Hiroaki Suga
      PNAS October 23, 2018 115 (43) 10959-10964; first published October 9, 2018. https://doi.org/10.1073/pnas.1809901115
    • You have access
      Protein shape modulates crowding effects
      Alex J. Guseman, Gerardo M. Perez Goncalves, Shannon L. Speer, Gregory B. Young, and Gary J. Pielak
      PNAS October 23, 2018 115 (43) 10965-10970; first published October 9, 2018. https://doi.org/10.1073/pnas.1810054115
    • You have access
      Why large icosahedral viruses need scaffolding proteins
      Siyu Li, Polly Roy, Alex Travesset, and Roya Zandi
      PNAS October 23, 2018 115 (43) 10971-10976; first published October 9, 2018. https://doi.org/10.1073/pnas.1807706115
  • Cell Biology

    • Open Access
      mTOR inhibitors lower an intrinsic barrier to virus infection mediated by IFITM3
      Guoli Shi, Stosh Ozog, Bruce E. Torbett, and Alex A. Compton
      PNAS October 23, 2018 115 (43) E10069-E10078; first published October 9, 2018. https://doi.org/10.1073/pnas.1811892115
    • You have access
      Mitosis-specific MRN complex promotes a mitotic signaling cascade to regulate spindle dynamics and chromosome segregation
      Ran Xu, Yixi Xu, Wei Huo, Zhicong Lv, Jingsong Yuan, Shaokai Ning, Qingsong Wang, Mei Hou, Ge Gao, Jianguo Ji, Junjie Chen, Rong Guo, and Dongyi Xu
      PNAS October 23, 2018 115 (43) E10079-E10088; first published October 8, 2018. https://doi.org/10.1073/pnas.1806665115
    • You have access
      XBP1s activation can globally remodel N-glycan structure distribution patterns
      Madeline Y. Wong, Kenny Chen, Aristotelis Antonopoulos, Brian T. Kasper, Mahender B. Dewal, Rebecca J. Taylor, Charles A. Whittaker, Pyae P. Hein, Anne Dell, Joseph C. Genereux, Stuart M. Haslam, Lara K. Mahal, and Matthew D. Shoulders
      PNAS October 23, 2018 115 (43) E10089-E10098; first published October 10, 2018. https://doi.org/10.1073/pnas.1805425115
    • Open Access
      Noncanonical autophagy at ER exit sites regulates procollagen turnover
      Shakib Omari, Elena Makareeva, Anna Roberts-Pilgrim, Lynn Mirigian, Michal Jarnik, Carolyn Ott, Jennifer Lippincott-Schwartz, and Sergey Leikin
      PNAS October 23, 2018 115 (43) E10099-E10108; first published October 4, 2018. https://doi.org/10.1073/pnas.1814552115
    • You have access
      Cryo-ET reveals the macromolecular reorganization of S. pombe mitotic chromosomes in vivo
      Shujun Cai, Chen Chen, Zhi Yang Tan, Yinyi Huang, Jian Shi, and Lu Gan
      PNAS October 23, 2018 115 (43) 10977-10982; first published October 8, 2018. https://doi.org/10.1073/pnas.1720476115
    • You have access
      SUMO protease SENP1 deSUMOylates and stabilizes c-Myc
      Xiao-Xin Sun, Yingxiao Chen, Yulong Su, Xiaoyan Wang, Krishna Mohan Chauhan, Juan Liang, Colin J. Daniel, Rosalie C. Sears, and Mu-Shui Dai
      PNAS October 23, 2018 115 (43) 10983-10988; first published October 10, 2018. https://doi.org/10.1073/pnas.1802932115
  • Ecology

    • Open Access
      Changes in temperature alter the relationship between biodiversity and ecosystem functioning
      Francisca C. García, Elvire Bestion, Ruth Warfield, and Gabriel Yvon-Durocher
      PNAS October 23, 2018 115 (43) 10989-10994; first published October 8, 2018. https://doi.org/10.1073/pnas.1805518115
    • You have access
      Magnetic map in nonanadromous Atlantic salmon
      Michelle M. Scanlan, Nathan F. Putman, Amanda M. Pollock, and David L. G. Noakes
      PNAS October 23, 2018 115 (43) 10995-10999; first published October 8, 2018. https://doi.org/10.1073/pnas.1807705115
  • Environmental Sciences

    • Open Access
      Native-state imaging of calcifying and noncalcifying microalgae reveals similarities in their calcium storage organelles
      Assaf Gal, Andrea Sorrentino, Keren Kahil, Eva Pereiro, Damien Faivre, and André Scheffel
      PNAS October 23, 2018 115 (43) 11000-11005; first published October 4, 2018. https://doi.org/10.1073/pnas.1804139115
  • Evolution

    • Open Access
      Selection and gene flow shape genomic islands that control floral guides
      Hugo Tavares, Annabel Whibley, David L. Field, Desmond Bradley, Matthew Couchman, Lucy Copsey, Joane Elleouet, Monique Burrus, Christophe Andalo, Miaomiao Li, Qun Li, Yongbiao Xue, Alexandra B. Rebocho, Nicolas H. Barton, and Enrico Coen
      PNAS October 23, 2018 115 (43) 11006-11011; first published October 8, 2018. https://doi.org/10.1073/pnas.1801832115
    • Open Access
      Whole-genome comparison of endogenous retrovirus segregation across wild and domestic host species populations
      Salvador Daniel Rivas-Carrillo, Mats E. Pettersson, Carl-Johan Rubin, and Patric Jern
      PNAS October 23, 2018 115 (43) 11012-11017; first published October 8, 2018. https://doi.org/10.1073/pnas.1815056115
  • Genetics

    • You have access
      Human leukemia mutations corrupt but do not abrogate GATA-2 function
      Koichi R. Katsumura, Charu Mehta, Kyle J. Hewitt, Alexandra A. Soukup, Isabela Fraga de Andrade, Erik A. Ranheim, Kirby D. Johnson, and Emery H. Bresnick
      PNAS October 23, 2018 115 (43) E10109-E10118; first published October 9, 2018. https://doi.org/10.1073/pnas.1813015115
    • Open Access
      Genetic variation in the SIM1 locus is associated with erectile dysfunction
      • From the Cover
      Eric Jorgenson, Navneet Matharu, Melody R. Palmer, Jie Yin, Jun Shan, Thomas J. Hoffmann, Khanh K. Thai, Xujia Zhou, James M. Hotaling, Gail P. Jarvik, Nadav Ahituv, Hunter Wessells, and Stephen K. Van Den Eeden
      PNAS October 23, 2018 115 (43) 11018-11023; first published October 8, 2018. https://doi.org/10.1073/pnas.1809872115

      See companion article:

      • Reply to Liu et al.: Tissue specificity of SIM1 gene expression and erectile dysfunction
        - Feb 12, 2019
    • You have access
      Human mitochondrial degradosome prevents harmful mitochondrial R loops and mitochondrial genome instability
      Sonia Silva, Lola P. Camino, and Andrés Aguilera
      PNAS October 23, 2018 115 (43) 11024-11029; first published October 9, 2018. https://doi.org/10.1073/pnas.1807258115
    • You have access
      Functional and evolutionary characterization of a secondary metabolite gene cluster in budding yeasts
      David J. Krause, Jacek Kominek, Dana A. Opulente, Xing-Xing Shen, Xiaofan Zhou, Quinn K. Langdon, Jeremy DeVirgilio, Amanda Beth Hulfachor, Cletus P. Kurtzman, Antonis Rokas, and Chris Todd Hittinger
      PNAS October 23, 2018 115 (43) 11030-11035; first published October 8, 2018. https://doi.org/10.1073/pnas.1806268115
  • Immunology and Inflammation

    • Open Access
      Regnase-1 controls colon epithelial regeneration via regulation of mTOR and purine metabolism
      Yasuharu Nagahama, Mayuko Shimoda, Guoliang Mao, Shailendra Kumar Singh, Yuuki Kozakai, Xin Sun, Daisuke Motooka, Shota Nakamura, Hiroki Tanaka, Takashi Satoh, Kazuhiko Maeda, and Shizuo Akira
      PNAS October 23, 2018 115 (43) 11036-11041; first published October 8, 2018. https://doi.org/10.1073/pnas.1809575115
    • You have access
      Glucose metabolism mediates disease tolerance in cerebral malaria
      Andrew Wang, Sarah C. Huen, Harding H. Luan, Kelly Baker, Henry Rinder, Carmen J. Booth, and Ruslan Medzhitov
      PNAS October 23, 2018 115 (43) 11042-11047; first published October 5, 2018. https://doi.org/10.1073/pnas.1806376115
    • You have access
      Toxicity of an Fc-engineered anti-CD40 antibody is abrogated by intratumoral injection and results in durable antitumor immunity
      David A. Knorr, Rony Dahan, and Jeffrey V. Ravetch
      PNAS October 23, 2018 115 (43) 11048-11053; first published October 8, 2018. https://doi.org/10.1073/pnas.1810566115
    • You have access
      C-type lectin receptor LSECtin-mediated apoptotic cell clearance by macrophages directs intestinal repair in experimental colitis
      Zaopeng Yang, Qian Li, Xin Wang, Xuepei Jiang, Dianyuan Zhao, Xin Lin, Fuchu He, and Li Tang
      PNAS October 23, 2018 115 (43) 11054-11059; first published October 9, 2018. https://doi.org/10.1073/pnas.1804094115
  • Medical Sciences

    • Open Access
      Differential regulation of PD-L1 expression by immune and tumor cells in NSCLC and the response to treatment with atezolizumab (anti–PD-L1)
      Marcin Kowanetz, Wei Zou, Scott N. Gettinger, Hartmut Koeppen, Mark Kockx, Peter Schmid, Edward E. Kadel III, Ignacio Wistuba, Jamie Chaft, Naiyer A. Rizvi, David R. Spigel, Alexander Spira, Fred R. Hirsch, Victor Cohen, Dustin Smith, Zach Boyd, Natasha Miley, Susan Flynn, Vincent Leveque, David S. Shames, Marcus Ballinger, Simonetta Mocci, Geetha Shankar, Roel Funke, Garret Hampton, Alan Sandler, Lukas Amler, Ira Mellman, Daniel S. Chen, and Priti S. Hegde
      PNAS October 23, 2018 115 (43) E10119-E10126; first published October 8, 2018. https://doi.org/10.1073/pnas.1802166115
    • Open Access
      iNOS promotes CD24+CD133+ liver cancer stem cell phenotype through a TACE/ADAM17-dependent Notch signaling pathway
      Ronghua Wang, Yawen Li, Allan Tsung, Hai Huang, Qiang Du, Muqing Yang, Meihong Deng, Si Xiong, Xiju Wang, Liyong Zhang, David A. Geller, Bin Cheng, and Timothy R. Billiar
      PNAS October 23, 2018 115 (43) E10127-E10136; first published October 8, 2018. https://doi.org/10.1073/pnas.1722100115
    • You have access
      Histone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches
      Prosun Das, Kylee J. Veazey, Hieu T. Van, Saakshi Kaushik, Kevin Lin, Yue Lu, Masaru Ishii, Junichi Kikuta, Kai Ge, Andre Nussenzweig, and Margarida A. Santos
      PNAS October 23, 2018 115 (43) E10137-E10146; first published October 8, 2018. https://doi.org/10.1073/pnas.1806019115
    • Open Access
      Metastatic growth instructed by neutrophil-derived transferrin
      Wei Liang, Qin Li, and Napoleone Ferrara
      PNAS October 23, 2018 115 (43) 11060-11065; first published October 9, 2018. https://doi.org/10.1073/pnas.1811717115
    • You have access
      Reducing dynamin 2 (DNM2) rescues DNM2-related dominant centronuclear myopathy
      Suzie Buono, Jacob A. Ross, Hichem Tasfaout, Yotam Levy, Christine Kretz, Leighla Tayefeh, John Matson, Shuling Guo, Pascal Kessler, Brett P. Monia, Marc Bitoun, Julien Ochala, Jocelyn Laporte, and Belinda S. Cowling
      PNAS October 23, 2018 115 (43) 11066-11071; first published October 5, 2018. https://doi.org/10.1073/pnas.1808170115
  • Microbiology

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      MmpL8MAB controls Mycobacterium abscessus virulence and production of a previously unknown glycolipid family
      Violaine Dubois, Albertus Viljoen, Laura Laencina, Vincent Le Moigne, Audrey Bernut, Faustine Dubar, Mickaël Blaise, Jean-Louis Gaillard, Yann Guérardel, Laurent Kremer, Jean-Louis Herrmann, and Fabienne Girard-Misguich
      PNAS October 23, 2018 115 (43) E10147-E10156; first published October 9, 2018. https://doi.org/10.1073/pnas.1812984115
    • Open Access
      Interplay between coronavirus, a cytoplasmic RNA virus, and nonsense-mediated mRNA decay pathway
      Masami Wada, Kumari G. Lokugamage, Keisuke Nakagawa, Krishna Narayanan, and Shinji Makino
      PNAS October 23, 2018 115 (43) E10157-E10166; first published October 8, 2018. https://doi.org/10.1073/pnas.1811675115
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      Elongation factor P is required to maintain proteome homeostasis at high growth rate
      Rodney Tollerson II, Anne Witzky, and Michael Ibba
      PNAS October 23, 2018 115 (43) 11072-11077; first published October 8, 2018. https://doi.org/10.1073/pnas.1812025115
  • Neuroscience

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      Dopaminergic basis for signaling belief updates, but not surprise, and the link to paranoia
      Matthew M. Nour, Tarik Dahoun, Philipp Schwartenbeck, Rick A. Adams, Thomas H. B. FitzGerald, Christopher Coello, Matthew B. Wall, Raymond J. Dolan, and Oliver D. Howes
      PNAS October 23, 2018 115 (43) E10167-E10176; first published October 8, 2018. https://doi.org/10.1073/pnas.1809298115
    • Open Access
      Activity-dependent bulk endocytosis proteome reveals a key presynaptic role for the monomeric GTPase Rab11
      A. C. Kokotos, J. Peltier, E. C. Davenport, M. Trost, and M. A. Cousin
      PNAS October 23, 2018 115 (43) E10177-E10186; first published October 9, 2018. https://doi.org/10.1073/pnas.1809189115
    • Open Access
      Chronic social stress-induced hyperglycemia in mice couples individual stress susceptibility to impaired spatial memory
      Michael A. van der Kooij, Tanja Jene, Giulia Treccani, Isabelle Miederer, Annika Hasch, Nadine Voelxen, Stefan Walenta, and Marianne B. Müller
      PNAS October 23, 2018 115 (43) E10187-E10196; first published October 9, 2018. https://doi.org/10.1073/pnas.1804412115
    • Open Access
      Long noncoding RNA GM12371 acts as a transcriptional regulator of synapse function
      Bindu L. Raveendra, Supriya Swarnkar, Yosef Avchalumov, Xin-An Liu, Eddie Grinman, Kerriann Badal, Adrian Reich, Bruce D. Pascal, and Sathyanarayanan V. Puthanveettil
      PNAS October 23, 2018 115 (43) E10197-E10205; first published October 8, 2018. https://doi.org/10.1073/pnas.1722587115
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      The brain’s hemodynamic response function rapidly changes under acute psychosocial stress in association with genetic and endocrine stress response markers
      • From the Cover
      Immanuel G. Elbau, Benedikt Brücklmeier, Manfred Uhr, Janine Arloth, Darina Czamara, Victor I. Spoormaker, Michael Czisch, Klaas Enno Stephan, Elisabeth B. Binder, and Philipp G. Sämann
      PNAS October 23, 2018 115 (43) E10206-E10215; first published September 10, 2018. https://doi.org/10.1073/pnas.1804340115

      See companion article:

      • Stress response regulation and the hemodynamic response
        - Oct 11, 2018
    • You have access
      DSCAM promotes self-avoidance in the developing mouse retina by masking the functions of cadherin superfamily members
      Andrew M. Garrett, Andre Khalil, David O. Walton, and Robert W. Burgess
      PNAS October 23, 2018 115 (43) E10216-E10224; first published October 8, 2018. https://doi.org/10.1073/pnas.1809430115
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      MRI-based assessment of function and dysfunction in myelinated axons
      William M. Spees, Tsen-Hsuan Lin, Peng Sun, Chunyu Song, Ajit George, Sam E. Gary, Hsin-Chieh Yang, and Sheng-Kwei Song
      PNAS October 23, 2018 115 (43) E10225-E10234; first published October 8, 2018. https://doi.org/10.1073/pnas.1801788115
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      Cbln2 and Cbln4 are expressed in distinct medial habenula-interpeduncular projections and contribute to different behavioral outputs
      Erica Seigneur, Jai S. Polepalli, and Thomas C. Südhof
      PNAS October 23, 2018 115 (43) E10235-E10244; first published October 4, 2018. https://doi.org/10.1073/pnas.1811086115
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      Yin-and-yang bifurcation of opioidergic circuits for descending analgesia at the midbrain of the mouse
      Jong-Hyun Kim, Gireesh Gangadharan, Junweon Byun, Eui-Ju Choi, C. Justin Lee, and Hee-Sup Shin
      PNAS October 23, 2018 115 (43) 11078-11083; first published October 8, 2018. https://doi.org/10.1073/pnas.1806082115
  • Pharmacology

    • Open Access
      p38α MAPK signaling drives pharmacologically reversible brain and gastrointestinal phenotypes in the SERT Ala56 mouse
      Matthew J. Robson, Meagan A. Quinlan, Kara Gross Margolis, Paula A. Gajewski-Kurdziel, Jeremy Veenstra-VanderWeele, Michael D. Gershon, D. Martin Watterson, and Randy D. Blakely
      PNAS October 23, 2018 115 (43) E10245-E10254; first published October 8, 2018. https://doi.org/10.1073/pnas.1809137115
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      Translating biased signaling in the ghrelin receptor system into differential in vivo functions
      Franziska Mende, Cecilie Hundahl, Bianca Plouffe, Louise Julie Skov, Bjørn Sivertsen, Andreas Nygaard Madsen, Michael Lückmann, Thi Ai Diep, Stefan Offermanns, Thomas Michael Frimurer, Michel Bouvier, and Birgitte Holst
      PNAS October 23, 2018 115 (43) E10255-E10264; first published October 9, 2018. https://doi.org/10.1073/pnas.1804003115
  • Plant Biology

    • You have access
      Quantitative and functional posttranslational modification proteomics reveals that TREPH1 plays a role in plant touch-delayed bolting
      Kai Wang, Zhu Yang, Dongjin Qing, Feng Ren, Shichang Liu, Qingsong Zheng, Jun Liu, Weiping Zhang, Chen Dai, Madeline Wu, E. Wassim Chehab, Janet Braam, and Ning Li
      PNAS October 23, 2018 115 (43) E10265-E10274; first published October 5, 2018. https://doi.org/10.1073/pnas.1814006115
  • Psychological and Cognitive Sciences

    • You have access
      Neural reactivation in parietal cortex enhances memory for episodically linked information
      Tanya R. Jonker, Halle Dimsdale-Zucker, Maureen Ritchey, Alex Clarke, and Charan Ranganath
      PNAS October 23, 2018 115 (43) 11084-11089; first published October 8, 2018. https://doi.org/10.1073/pnas.1800006115
    • You have access
      Humans incorporate attention-dependent uncertainty into perceptual decisions and confidence
      Rachel N. Denison, William T. Adler, Marisa Carrasco, and Wei Ji Ma
      PNAS October 23, 2018 115 (43) 11090-11095; first published October 8, 2018. https://doi.org/10.1073/pnas.1717720115
  • Sustainability Science

    • Open Access
      Bottom trawl fishing footprints on the world’s continental shelves
      Ricardo O. Amoroso, C. Roland Pitcher, Adriaan D. Rijnsdorp, Robert A. McConnaughey, Ana M. Parma, Petri Suuronen, Ole R. Eigaard, Francois Bastardie, Niels T. Hintzen, Franziska Althaus, Susan Jane Baird, Jenny Black, Lene Buhl-Mortensen, Alexander B. Campbell, Rui Catarino, Jeremy Collie, James H. Cowan Jr., Deon Durholtz, Nadia Engstrom, Tracey P. Fairweather, Heino O. Fock, Richard Ford, Patricio A. Gálvez, Hans Gerritsen, María Eva Góngora, Jessica A. González, Jan G. Hiddink, Kathryn M. Hughes, Steven S. Intelmann, Chris Jenkins, Patrik Jonsson, Paulus Kainge, Mervi Kangas, Johannes N. Kathena, Stefanos Kavadas, Rob W. Leslie, Steve G. Lewis, Mathieu Lundy, David Makin, Julie Martin, Tessa Mazor, Genoveva Gonzalez-Mirelis, Stephen J. Newman, Nadia Papadopoulou, Paulette E. Posen, Wayne Rochester, Tommaso Russo, Antonello Sala, Jayson M. Semmens, Cristina Silva, Angelo Tsolos, Bart Vanelslander, Corey B. Wakefield, Brent A. Wood, Ray Hilborn, Michel J. Kaiser, and Simon Jennings
      PNAS October 23, 2018 115 (43) E10275-E10282; first published October 8, 2018. https://doi.org/10.1073/pnas.1802379115
  • Systems Biology

    • You have access
      Characterizing posttranslational modifications in prokaryotic metabolism using a multiscale workflow
      Elizabeth Brunk, Roger L. Chang, Jing Xia, Hooman Hefzi, James T. Yurkovich, Donghyuk Kim, Evan Buckmiller, Harris H. Wang, Byung-Kwan Cho, Chen Yang, Bernhard O. Palsson, George M. Church, and Nathan E. Lewis
      PNAS October 23, 2018 115 (43) 11096-11101; first published October 9, 2018. https://doi.org/10.1073/pnas.1811971115

Corrections (Online Only)

  • You have access
    Correction for Kneller, Franck–Condon picture of incoherent neutron scattering
    PNAS October 23, 2018 115 (43) E10283; first published October 15, 2018. https://doi.org/10.1073/pnas.1816793115
  • You have access
    Correction for Liao et al., Metal–insulator-transition engineering by modulation tilt-control in perovskite nickelates for room temperature optical switching
    PNAS October 23, 2018 115 (43) E10284; first published October 15, 2018. https://doi.org/10.1073/pnas.1816794115
  • You have access
    Correction for Baldwin and Mussweiler, The culture of social comparison
    PNAS October 23, 2018 115 (43) E10285; first published October 15, 2018. https://doi.org/10.1073/pnas.1816586115
  • You have access
    Correction for Li et al., Mutually inhibitory Ras-PI(3,4)P2 feedback loops mediate cell migration
    PNAS October 23, 2018 115 (43) E10286; first published October 15, 2018. https://doi.org/10.1073/pnas.1816155115
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Proceedings of the National Academy of Sciences: 115 (43)
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