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Research Article

Infectious virus in exhaled breath of symptomatic seasonal influenza cases from a college community

Jing Yan, Michael Grantham, Jovan Pantelic, P. Jacob Bueno de Mesquita, Barbara Albert, Fengjie Liu, Sheryl Ehrman, View ORCID ProfileDonald K. Milton, and EMIT Consortium
PNAS January 30, 2018 115 (5) 1081-1086; first published January 18, 2018; https://doi.org/10.1073/pnas.1716561115
Jing Yan
aMaryland Institute for Applied Environmental Health, School of Public Health, University of Maryland, College Park, MD 20742;
bDepartment of Chemical and Biomolecular Engineering, Clark School of Engineering, University of Maryland, College Park, MD 20742
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Michael Grantham
aMaryland Institute for Applied Environmental Health, School of Public Health, University of Maryland, College Park, MD 20742;
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Jovan Pantelic
aMaryland Institute for Applied Environmental Health, School of Public Health, University of Maryland, College Park, MD 20742;
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P. Jacob Bueno de Mesquita
aMaryland Institute for Applied Environmental Health, School of Public Health, University of Maryland, College Park, MD 20742;
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Barbara Albert
aMaryland Institute for Applied Environmental Health, School of Public Health, University of Maryland, College Park, MD 20742;
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Fengjie Liu
aMaryland Institute for Applied Environmental Health, School of Public Health, University of Maryland, College Park, MD 20742;
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Sheryl Ehrman
bDepartment of Chemical and Biomolecular Engineering, Clark School of Engineering, University of Maryland, College Park, MD 20742
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Donald K. Milton
aMaryland Institute for Applied Environmental Health, School of Public Health, University of Maryland, College Park, MD 20742;
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  • ORCID record for Donald K. Milton
  • For correspondence: dmilton@umd.edu
aMaryland Institute for Applied Environmental Health, School of Public Health, University of Maryland, College Park, MD 20742;
bDepartment of Chemical and Biomolecular Engineering, Clark School of Engineering, University of Maryland, College Park, MD 20742
  1. Edited by Peter Palese, Icahn School of Medicine at Mount Sinai, New York, NY, and approved December 15, 2017 (received for review September 19, 2017)

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Article Information

vol. 115 no. 5 1081-1086
DOI: 
https://doi.org/10.1073/pnas.1716561115
PubMed: 
29348203

Published By: 
National Academy of Sciences
Print ISSN: 
0027-8424
Online ISSN: 
1091-6490
History: 
  • Published in issue January 30, 2018.
  • Published first January 18, 2018.

Article Versions

  • Previous version (January 18, 2018 - 13:00).
  • You are viewing the most recent version of this article.
Copyright & Usage: 
Copyright © 2018 the Author(s). Published by PNAS. This open access article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND).

Author Information

  1. Jing Yana,b,
  2. Michael Granthama,1,
  3. Jovan Pantelica,2,
  4. P. Jacob Bueno de Mesquitaa,
  5. Barbara Alberta,
  6. Fengjie Liua,3,
  7. Sheryl Ehrmanb,4,
  8. Donald K. Miltona,5,
  9. EMIT Consortium6
  1. aMaryland Institute for Applied Environmental Health, School of Public Health, University of Maryland, College Park, MD 20742;
  2. bDepartment of Chemical and Biomolecular Engineering, Clark School of Engineering, University of Maryland, College Park, MD 20742
    1. Edited by Peter Palese, Icahn School of Medicine at Mount Sinai, New York, NY, and approved December 15, 2017 (received for review September 19, 2017)

    Footnotes

    • ↵1Present address: Department of Biology, Missouri Western State University, St. Joseph, MO 64507.

    • ↵2Present address: Center for the Built Environment, University of California, Berkeley, CA 94720.

    • ↵3Present address: Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD 20903.

    • ↵4Present address: Davidson College of Engineering, San José State University, San José, CA 95192.

    • ↵5To whom correspondence should be addressed. Email: dmilton{at}umd.edu.
    • ↵6A complete list of the EMIT Consortium can be found in the Supporting Information.

    • Author contributions: S.E., D.K.M., and E.C. designed research; J.Y., M.G., J.P., P.J.B.d.M., B.A., F.L., S.E., and D.K.M. performed research; D.K.M. contributed new reagents/analytic tools; J.Y. and D.K.M. analyzed data; and J.Y., M.G., and D.K.M. wrote the paper.

    • The authors declare no conflict of interest.

    • This article is a PNAS Direct Submission.

    • This article contains supporting information online at www.pnas.org/lookup/suppl/doi:10.1073/pnas.1716561115/-/DCSupplemental.

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    Aug 201841584975280
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    Aerosol shedding of infectious influenza virus
    Jing Yan, Michael Grantham, Jovan Pantelic, P. Jacob Bueno de Mesquita, Barbara Albert, Fengjie Liu, Sheryl Ehrman, Donald K. Milton, EMIT Consortium
    Proceedings of the National Academy of Sciences Jan 2018, 115 (5) 1081-1086; DOI: 10.1073/pnas.1716561115

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    Aerosol shedding of infectious influenza virus
    Jing Yan, Michael Grantham, Jovan Pantelic, P. Jacob Bueno de Mesquita, Barbara Albert, Fengjie Liu, Sheryl Ehrman, Donald K. Milton, EMIT Consortium
    Proceedings of the National Academy of Sciences Jan 2018, 115 (5) 1081-1086; DOI: 10.1073/pnas.1716561115
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    Mara Reed and Michael Manga explore why Yellowstone's Steamboat Geyser resumed erupting in 2018.
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    Birds nestling on tree branches
    Parent–offspring conflict in songbird fledging
    Some songbird parents might improve their own fitness by manipulating their offspring into leaving the nest early, at the cost of fledgling survival, a study finds.
    Image credit: Gil Eckrich (photographer).

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