New Research In
Physical Sciences
Social Sciences
Featured Portals
Articles by Topic
Biological Sciences
Featured Portals
Articles by Topic
- Agricultural Sciences
- Anthropology
- Applied Biological Sciences
- Biochemistry
- Biophysics and Computational Biology
- Cell Biology
- Developmental Biology
- Ecology
- Environmental Sciences
- Evolution
- Genetics
- Immunology and Inflammation
- Medical Sciences
- Microbiology
- Neuroscience
- Pharmacology
- Physiology
- Plant Biology
- Population Biology
- Psychological and Cognitive Sciences
- Sustainability Science
- Systems Biology
Table of Contents
April 30, 2019; vol. 116 no. 18
This Week in PNAS
Inner Workings
An over-the-shoulder look at scientists at work.
- You have accessInner Workings: Genomics blazes a trail to improved cannabis cultivation
- Front Matter
Elie Dolgin
Profile
- You have accessProfile of Zhisheng AnJennifer ViegasPNAS April 30, 2019 116 (18) 8641-8643; first published April 15, 2019. https://doi.org/10.1073/pnas.1904581116
See companion article:
Letters
- You have accessTime domain versus energy domain neutron scattering analysis of protein dynamicsWolfgang DosterPNAS April 30, 2019 116 (18) 8649-8650; first published April 12, 2019. https://doi.org/10.1073/pnas.1821562116
- You have accessReply to Doster: Franck–Condon and Van Hove formulation of quasielastic neutron scattering from complex systemsGerald R. KnellerPNAS April 30, 2019 116 (18) 8651-8652; first published April 12, 2019. https://doi.org/10.1073/pnas.1901851116
See companion article:
- Franck–Condon picture of incoherent neutron scattering- Aug 30, 2018
- You have accessPhototransduction gain at the G-protein, transducin, and effector protein, phosphodiesterase-6, stages in retinal rodsMartin Heck, Klaus Peter Hofmann, Timothy W. Kraft, and Trevor D. LambPNAS April 30, 2019 116 (18) 8653-8654; first published April 30, 2019. https://doi.org/10.1073/pnas.1904017116
- You have accessReply to Heck et al.: Signal amplification at the rhodopsin-to-transducin·phosphodiesterase step in rod phototransductionK.-W. Yau, W. W. S. Yue, and D. SilvermanPNAS April 30, 2019 116 (18) 8655-8656; first published April 30, 2019. https://doi.org/10.1073/pnas.1904339116
See companion article:
- Elementary response triggered by transducin in retinal rods- Feb 22, 2019
Physical Sciences
Applied Physical Sciences
- You have accessDeep learning in turbulent convection networksEnrico Fonda, Ambrish Pandey, Jörg Schumacher, and Katepalli R. SreenivasanPNAS April 30, 2019 116 (18) 8667-8672; first published April 15, 2019. https://doi.org/10.1073/pnas.1900358116
- Open AccessScale-free resilience of real traffic jamsLimiao Zhang, Guanwen Zeng, Daqing Li, Hai-Jun Huang, H. Eugene Stanley, and Shlomo HavlinPNAS April 30, 2019 116 (18) 8673-8678; first published April 12, 2019. https://doi.org/10.1073/pnas.1814982116
- Open AccessShock growth of ice crystal near equilibrium melting pressure under dynamic compressionYong-Jae Kim, Yun-Hee Lee, Sooheyong Lee, Hiroki Nada, and Geun Woo LeePNAS April 30, 2019 116 (18) 8679-8684; first published April 15, 2019. https://doi.org/10.1073/pnas.1818122116
Biophysics and Computational Biology
- You have accessA diecast mineralization process forms the tough mantis shrimp dactyl clubShahrouz Amini, Maryam Tadayon, Jun Jie Loke, Akshita Kumar, Deepankumar Kanagavel, Hortense Le Ferrand, Martial Duchamp, Manfred Raida, Radoslaw M. Sobota, Liyan Chen, Shawn Hoon, and Ali MiserezPNAS April 30, 2019 116 (18) 8685-8692; first published April 11, 2019. https://doi.org/10.1073/pnas.1816835116
- You have accessUnified energetics analysis unravels SpCas9 cleavage activity for optimal gRNA designDong Zhang, Travis Hurst, Dongsheng Duan, and Shi-Jie ChenPNAS April 30, 2019 116 (18) 8693-8698; first published April 15, 2019. https://doi.org/10.1073/pnas.1820523116
- Open AccessStructural dynamics and transient lipid binding of synaptobrevin-2 tune SNARE assembly and membrane fusionNils-Alexander Lakomek, Halenur Yavuz, Reinhard Jahn, and Ángel Pérez-LaraPNAS April 30, 2019 116 (18) 8699-8708; first published April 11, 2019. https://doi.org/10.1073/pnas.1813194116
- You have accessCommonly used FRET fluorophores promote collapse of an otherwise disordered proteinJoshua A. Riback, Micayla A. Bowman, Adam M. Zmyslowski, Kevin W. Plaxco, Patricia L. Clark, and Tobin R. SosnickPNAS April 30, 2019 116 (18) 8889-8894; first published April 16, 2019. https://doi.org/10.1073/pnas.1813038116
Chemistry
- You have accessIntrinsically cell-penetrating multivalent and multitargeting ligands for myotonic dystrophy type 1JuYeon Lee, Yugang Bai, Ullas V. Chembazhi, Shaohong Peng, Kevin Yum, Long M. Luu, Lauren D. Hagler, Julio F. Serrano, H. Y. Edwin Chan, Auinash Kalsotra, and Steven C. ZimmermanPNAS April 30, 2019 116 (18) 8709-8714; first published April 11, 2019. https://doi.org/10.1073/pnas.1820827116
- Open AccessCorrelated interfacial water transport and proton conductivity in perfluorosulfonic acid membranesXiao Ling, Mischa Bonn, Katrin F. Domke, and Sapun H. ParekhPNAS April 30, 2019 116 (18) 8715-8720; first published April 15, 2019. https://doi.org/10.1073/pnas.1817470116
- Open AccessModular, stereocontrolled Cβ–H/Cα–C activation of alkyl carboxylic acidsMing Shang, Karla S. Feu, Julien C. Vantourout, Lisa M. Barton, Heather L. Osswald, Nobutaka Kato, Kerstin Gagaring, Case W. McNamara, Gang Chen, Liang Hu, Shengyang Ni, Paula Fernández-Canelas, Miao Chen, Rohan R. Merchant, Tian Qin, Stuart L. Schreiber, Bruno Melillo, Jin-Quan Yu, and Phil S. BaranPNAS April 30, 2019 116 (18) 8721-8727; first published April 17, 2019. https://doi.org/10.1073/pnas.1903048116
Computer Sciences
- You have accessMachine learning-assisted directed protein evolution with combinatorial librariesZachary Wu, S. B. Jennifer Kan, Russell D. Lewis, Bruce J. Wittmann, and Frances H. ArnoldPNAS April 30, 2019 116 (18) 8852-8858; first published April 12, 2019. https://doi.org/10.1073/pnas.1901979116
Earth, Atmospheric, and Planetary Sciences
- Open AccessSevere haze in northern China: A synergy of anthropogenic emissions and atmospheric processes
- Inaugural Article
Zhisheng An, Ru-Jin Huang, Renyi Zhang, Xuexi Tie, Guohui Li, Junji Cao, Weijian Zhou, Zhengguo Shi, Yongming Han, Zhaolin Gu, and Yuemeng JiPNAS April 30, 2019 116 (18) 8657-8666; first published April 15, 2019. https://doi.org/10.1073/pnas.1900125116See companion article:
- Profile of Zhisheng An- Apr 15, 2019
- You have accessClimate models can correctly simulate the continuum of global-average temperature variabilityFeng Zhu, Julien Emile-Geay, Nicholas P. McKay, Gregory J. Hakim, Deborah Khider, Toby R. Ault, Eric J. Steig, Sylvia Dee, and James W. KirchnerPNAS April 30, 2019 116 (18) 8728-8733; first published April 15, 2019. https://doi.org/10.1073/pnas.1809959116
- You have accessAnthropogenic strath terrace formation caused by reduced sediment retentionSarah A. Schanz, David R. Montgomery, and Brian D. CollinsPNAS April 30, 2019 116 (18) 8734-8739; first published April 15, 2019. https://doi.org/10.1073/pnas.1814627116
- You have accessK isotopes as a tracer for continental weathering and geological K cyclingShilei Li, Weiqiang Li, Brian L. Beard, Maureen E. Raymo, Xiaomin Wang, Yang Chen, and Jun ChenPNAS April 30, 2019 116 (18) 8740-8745; first published April 15, 2019. https://doi.org/10.1073/pnas.1811282116
- You have accessNeoproterozoic to early Phanerozoic rise in island arc redox state due to deep ocean oxygenation and increased marine sulfate levelsDaniel A. Stolper and Claire E. BucholzPNAS April 30, 2019 116 (18) 8746-8755; first published April 11, 2019. https://doi.org/10.1073/pnas.1821847116
Engineering
- You have accessDisconnection description of triple-junction motionSpencer L. Thomas, Chaozhen Wei, Jian Han, Yang Xiang, and David J. SrolovitzPNAS April 30, 2019 116 (18) 8756-8765; first published April 15, 2019. https://doi.org/10.1073/pnas.1820789116
- You have accessMacromolecular relaxation, strain, and extensibility determine elastocapillary thinning and extensional viscosity of polymer solutionsJelena Dinic and Vivek SharmaPNAS April 30, 2019 116 (18) 8766-8774; first published April 12, 2019. https://doi.org/10.1073/pnas.1820277116
- You have accessRapid screening of engineered microbial therapies in a 3D multicellular modelTetsuhiro Harimoto, Zakary S. Singer, Oscar S. Velazquez, Joanna Zhang, Samuel Castro, Taylor E. Hinchliffe, William Mather, and Tal DaninoPNAS April 30, 2019 116 (18) 9002-9007; first published April 17, 2019. https://doi.org/10.1073/pnas.1820824116
Environmental Sciences
- Open AccessFine-scale damage estimates of particulate matter air pollution reveal opportunities for location-specific mitigation of emissionsAndrew L. Goodkind, Christopher W. Tessum, Jay S. Coggins, Jason D. Hill, and Julian D. MarshallPNAS April 30, 2019 116 (18) 8775-8780; first published April 8, 2019. https://doi.org/10.1073/pnas.1816102116
- You have accessDating glacier ice of the last millennium by quantum technologyZhongyi Feng, Pascal Bohleber, Sven Ebser, Lisa Ringena, Maximilian Schmidt, Arne Kersting, Philip Hopkins, Helene Hoffmann, Andrea Fischer, Werner Aeschbach, and Markus K. OberthalerPNAS April 30, 2019 116 (18) 8781-8786; first published April 17, 2019. https://doi.org/10.1073/pnas.1816468116
Mathematics
- You have accessCounterexamples in scale calculusBenjamin Filippenko, Zhengyi Zhou, and Katrin WehrheimPNAS April 30, 2019 116 (18) 8787-8797; first published April 12, 2019. https://doi.org/10.1073/pnas.1811701116
Physics
- You have accessGiant nonvolatile resistive switching in a Mott oxide and ferroelectric hybridPavel Salev, Javier del Valle, Yoav Kalcheim, and Ivan K. SchullerPNAS April 30, 2019 116 (18) 8798-8802; first published April 11, 2019. https://doi.org/10.1073/pnas.1822138116
- You have accessStrain-induced spontaneous Hall effect in an epitaxial thin film of a Luttinger semimetalTakumi Ohtsuki, Zhaoming Tian, Akira Endo, Mario Halim, Shingo Katsumoto, Yoshimitsu Kohama, Koichi Kindo, Mikk Lippmaa, and Satoru NakatsujiPNAS April 30, 2019 116 (18) 8803-8808; first published April 15, 2019. https://doi.org/10.1073/pnas.1819489116
- You have accessPhase-conjugate mirror for water waves driven by the Faraday instabilityVincent Bacot, Guillaume Durey, Antonin Eddi, Mathias Fink, and Emmanuel FortPNAS April 30, 2019 116 (18) 8809-8814; first published April 17, 2019. https://doi.org/10.1073/pnas.1818742116
- Open AccessHow a well-adapting immune system remembersAndreas Mayer, Vijay Balasubramanian, Aleksandra M. Walczak, and Thierry MoraPNAS April 30, 2019 116 (18) 8815-8823; first published April 15, 2019. https://doi.org/10.1073/pnas.1812810116
Social Sciences
Anthropology
- Open AccessEarly tropical crop production in marginal subtropical and temperate Polynesia
- From the Cover
Matthew Prebble, Atholl J. Anderson, Paul Augustinus, Joshua Emmitt, Stewart J. Fallon, Louise L. Furey, Simon J. Holdaway, Alex Jorgensen, Thegn N. Ladefoged, Peter J. Matthews, Jean-Yves Meyer, Rebecca Phillipps, Rod Wallace, and Nicholas PorchPNAS April 30, 2019 116 (18) 8824-8833; first published April 8, 2019. https://doi.org/10.1073/pnas.1821732116See companion article:
Economic Sciences
- You have accessEvolution of social norms and correlated equilibriaBryce Morsky and Erol AkçayPNAS April 30, 2019 116 (18) 8834-8839; first published April 11, 2019. https://doi.org/10.1073/pnas.1817095116
Environmental Sciences
- You have accessClimate change and educational attainment in the global tropicsHeather Randell and Clark GrayPNAS April 30, 2019 116 (18) 8840-8845; first published April 15, 2019. https://doi.org/10.1073/pnas.1817480116
Psychological and Cognitive Sciences
- You have accessSame-sex marriage legalization associated with reduced implicit and explicit antigay bias
- From the Cover
Eugene K. Ofosu, Michelle K. Chambers, Jacqueline M. Chen, and Eric HehmanPNAS April 30, 2019 116 (18) 8846-8851; first published April 15, 2019. https://doi.org/10.1073/pnas.1806000116 - Open AccessFunctional connectomics of affective and psychotic pathologyJustin T. Baker, Daniel G. Dillon, Lauren M. Patrick, Joshua L. Roffman, Roscoe O. Brady Jr., Diego A. Pizzagalli, Dost Öngür, and Avram J. HolmesPNAS April 30, 2019 116 (18) 9050-9059; first published April 15, 2019. https://doi.org/10.1073/pnas.1820780116
Sustainability Science
- Open AccessFine-scale damage estimates of particulate matter air pollution reveal opportunities for location-specific mitigation of emissionsAndrew L. Goodkind, Christopher W. Tessum, Jay S. Coggins, Jason D. Hill, and Julian D. MarshallPNAS April 30, 2019 116 (18) 8775-8780; first published April 8, 2019. https://doi.org/10.1073/pnas.1816102116
- You have accessClimate change and educational attainment in the global tropicsHeather Randell and Clark GrayPNAS April 30, 2019 116 (18) 8840-8845; first published April 15, 2019. https://doi.org/10.1073/pnas.1817480116
Biological Sciences
Applied Biological Sciences
- You have accessMachine learning-assisted directed protein evolution with combinatorial librariesZachary Wu, S. B. Jennifer Kan, Russell D. Lewis, Bruce J. Wittmann, and Frances H. ArnoldPNAS April 30, 2019 116 (18) 8852-8858; first published April 12, 2019. https://doi.org/10.1073/pnas.1901979116
Biochemistry
- You have accessA diecast mineralization process forms the tough mantis shrimp dactyl clubShahrouz Amini, Maryam Tadayon, Jun Jie Loke, Akshita Kumar, Deepankumar Kanagavel, Hortense Le Ferrand, Martial Duchamp, Manfred Raida, Radoslaw M. Sobota, Liyan Chen, Shawn Hoon, and Ali MiserezPNAS April 30, 2019 116 (18) 8685-8692; first published April 11, 2019. https://doi.org/10.1073/pnas.1816835116
- You have accessIntrinsically cell-penetrating multivalent and multitargeting ligands for myotonic dystrophy type 1JuYeon Lee, Yugang Bai, Ullas V. Chembazhi, Shaohong Peng, Kevin Yum, Long M. Luu, Lauren D. Hagler, Julio F. Serrano, H. Y. Edwin Chan, Auinash Kalsotra, and Steven C. ZimmermanPNAS April 30, 2019 116 (18) 8709-8714; first published April 11, 2019. https://doi.org/10.1073/pnas.1820827116
- You have accessInteraction between p53 N terminus and core domain regulates specific and nonspecific DNA bindingFan He, Wade Borcherds, Tanjing Song, Xi Wei, Mousumi Das, Lihong Chen, Gary W. Daughdrill, and Jiandong ChenPNAS April 30, 2019 116 (18) 8859-8868; first published April 15, 2019. https://doi.org/10.1073/pnas.1903077116
- You have accessStructural insight into TRPV5 channel function and modulationShangyu Dang, Mark K. van Goor, Daniel Asarnow, YongQiang Wang, David Julius, Yifan Cheng, and Jenny van der WijstPNAS April 30, 2019 116 (18) 8869-8878; first published April 11, 2019. https://doi.org/10.1073/pnas.1820323116
- You have accessCytosolic Fe-superoxide dismutase safeguards Trypanosoma cruzi from macrophage-derived superoxide radicalAlejandra Martínez, Carolina Prolo, Damián Estrada, Natalia Rios, María Noel Alvarez, María Dolores Piñeyro, Carlos Robello, Rafael Radi, and Lucía PiacenzaPNAS April 30, 2019 116 (18) 8879-8888; first published April 12, 2019. https://doi.org/10.1073/pnas.1821487116
Biophysics and Computational Biology
- You have accessCommonly used FRET fluorophores promote collapse of an otherwise disordered proteinJoshua A. Riback, Micayla A. Bowman, Adam M. Zmyslowski, Kevin W. Plaxco, Patricia L. Clark, and Tobin R. SosnickPNAS April 30, 2019 116 (18) 8889-8894; first published April 16, 2019. https://doi.org/10.1073/pnas.1813038116
- You have accessα-Sheet secondary structure in amyloid β-peptide drives aggregation and toxicity in Alzheimer’s diseaseDylan Shea, Cheng-Chieh Hsu, Timothy M. Bi, Natasha Paranjapye, Matthew Carter Childers, Joshua Cochran, Colson P. Tomberlin, Libo Wang, Daniel Paris, Jeffrey Zonderman, Gabriele Varani, Christopher D. Link, Mike Mullan, and Valerie DaggettPNAS April 30, 2019 116 (18) 8895-8900; first published April 19, 2019. https://doi.org/10.1073/pnas.1820585116
- Open AccessCoherent directed movement toward food modeled in Trichoplax, a ciliated animal lacking a nervous systemCarolyn L. Smith, Thomas S. Reese, Tzipe Govezensky, and Rafael A. BarrioPNAS April 30, 2019 116 (18) 8901-8908; first published April 12, 2019. https://doi.org/10.1073/pnas.1815655116
Cell Biology
- You have accessDistinct segregation patterns of yeast cell-peripheral proteins uncovered by a method for protein segregatome analysisShinju Sugiyama and Motomasa TanakaPNAS April 30, 2019 116 (18) 8909-8918; first published April 11, 2019. https://doi.org/10.1073/pnas.1819715116
Ecology
- Open AccessEarly tropical crop production in marginal subtropical and temperate Polynesia
- From the Cover
Matthew Prebble, Atholl J. Anderson, Paul Augustinus, Joshua Emmitt, Stewart J. Fallon, Louise L. Furey, Simon J. Holdaway, Alex Jorgensen, Thegn N. Ladefoged, Peter J. Matthews, Jean-Yves Meyer, Rebecca Phillipps, Rod Wallace, and Nicholas PorchPNAS April 30, 2019 116 (18) 8824-8833; first published April 8, 2019. https://doi.org/10.1073/pnas.1821732116See companion article:
- You have accessSocial alliances improve rank and fitness in convention-based societies
- From the Cover
Eli D. Strauss and Kay E. HolekampPNAS April 30, 2019 116 (18) 8919-8924; first published March 11, 2019. https://doi.org/10.1073/pnas.1810384116See companion article:
- Hyena politics: The dynamics of dynasties- Mar 25, 2019
- You have accessPredators attacking virtual prey reveal the costs and benefits of leadershipChristos C. Ioannou, Florence Rocque, James E. Herbert-Read, Callum Duffield, and Josh A. FirthPNAS April 30, 2019 116 (18) 8925-8930; first published April 15, 2019. https://doi.org/10.1073/pnas.1816323116
Environmental Sciences
- You have accessEnvironmental DNA for improved detection and environmental surveillance of schistosomiasisMita E. Sengupta, Micaela Hellström, Henry C. Kariuki, Annette Olsen, Philip F. Thomsen, Helena Mejer, Eske Willerslev, Mariam T. Mwanje, Henry Madsen, Thomas K. Kristensen, Anna-Sofie Stensgaard, and Birgitte J. VennervaldPNAS April 30, 2019 116 (18) 8931-8940; first published April 11, 2019. https://doi.org/10.1073/pnas.1815046116
Evolution
- You have accessEvolution of social norms and correlated equilibriaBryce Morsky and Erol AkçayPNAS April 30, 2019 116 (18) 8834-8839; first published April 11, 2019. https://doi.org/10.1073/pnas.1817095116
- You have accessTesting the role of trait reversal in evolutionary diversification using song loss in wild cricketsNathan W. Bailey, Sonia Pascoal, and Fernando Montealegre-ZPNAS April 30, 2019 116 (18) 8941-8949; first published April 16, 2019. https://doi.org/10.1073/pnas.1818998116
- Open AccessExaggeration and cooption of innate immunity for social defenseMayako Kutsukake, Minoru Moriyama, Shuji Shigenobu, Xian-Ying Meng, Naruo Nikoh, Chiyo Noda, Satoru Kobayashi, and Takema FukatsuPNAS April 30, 2019 116 (18) 8950-8959; first published April 15, 2019. https://doi.org/10.1073/pnas.1900917116
Genetics
- Open AccessFunctional characterization of 3D protein structures informed by human genetic diversityMichael Hicks, Istvan Bartha, Julia di Iulio, J. Craig Venter, and Amalio TelentiPNAS April 30, 2019 116 (18) 8960-8965; first published April 15, 2019. https://doi.org/10.1073/pnas.1820813116
Immunology and Inflammation
- You have accessDesigner covalent heterobivalent inhibitors prevent IgE-dependent responses to peanut allergen
- From the Cover
Peter E. Deak, Baksun Kim, Amina Abdul Qayum, Jaeho Shin, Girish Vitalpur, Kirsten M. Kloepfer, Matthew J. Turner, Neal Smith, Wayne G. Shreffler, Tanyel Kiziltepe, Mark H. Kaplan, and Basar BilgicerPNAS April 30, 2019 116 (18) 8966-8974; first published April 8, 2019. https://doi.org/10.1073/pnas.1820417116 - You have accessHypoxia-inducible factors in CD4+ T cells promote metabolism, switch cytokine secretion, and T cell help in humoral immunitySung Hoon Cho, Ariel L. Raybuck, Julianna Blagih, Edna Kemboi, Volker H. Haase, Russell G. Jones, and Mark R. BoothbyPNAS April 30, 2019 116 (18) 8975-8984; first published April 15, 2019. https://doi.org/10.1073/pnas.1811702116
- You have accessDNA threads released by activated CD4+ T lymphocytes provide autocrine costimulationMassimo Costanza, Pietro L. Poliani, Paola Portararo, Barbara Cappetti, Silvia Musio, Francesca Pagani, Lawrence Steinman, Mario P. Colombo, Rosetta Pedotti, and Sabina SangalettiPNAS April 30, 2019 116 (18) 8985-8994; first published April 15, 2019. https://doi.org/10.1073/pnas.1822013116
- Open AccessSelect sequencing of clonally expanded CD8+ T cells reveals limits to clonal expansionHuang Huang, Michael J. Sikora, Saiful Islam, Roshni Roy Chowdhury, Yueh-hsiu Chien, Thomas J. Scriba, Mark M. Davis, and Lars M. SteinmetzPNAS April 30, 2019 116 (18) 8995-9001; first published April 16, 2019. https://doi.org/10.1073/pnas.1902649116
Medical Sciences
- You have accessRapid screening of engineered microbial therapies in a 3D multicellular modelTetsuhiro Harimoto, Zakary S. Singer, Oscar S. Velazquez, Joanna Zhang, Samuel Castro, Taylor E. Hinchliffe, William Mather, and Tal DaninoPNAS April 30, 2019 116 (18) 9002-9007; first published April 17, 2019. https://doi.org/10.1073/pnas.1820824116
- You have accessInherited predisposition to malignant mesothelioma and overall survival following platinum chemotherapyRaffit Hassan, Betsy Morrow, Anish Thomas, Tom Walsh, Ming K. Lee, Suleyman Gulsuner, Meghana Gadiraju, Vasiliki Panou, Shaojian Gao, Idrees Mian, Javed Khan, Mark Raffeld, Snehal Patel, Liqiang Xi, Jun S. Wei, Mary Hesdorffer, Jingli Zhang, Kathleen Calzone, Arpita Desai, Emerson Padiernos, Christine Alewine, David S. Schrump, Seth M. Steinberg, Hedy L. Kindler, Mary-Claire King, and Jane E. ChurpekPNAS April 30, 2019 116 (18) 9008-9013; first published April 11, 2019. https://doi.org/10.1073/pnas.1821510116
- Open AccessSingle-cell whole-genome sequencing reveals the functional landscape of somatic mutations in B lymphocytes across the human lifespanLei Zhang, Xiao Dong, Moonsook Lee, Alexander Y. Maslov, Tao Wang, and Jan VijgPNAS April 30, 2019 116 (18) 9014-9019; first published April 16, 2019. https://doi.org/10.1073/pnas.1902510116
- You have accessCancer stemness, intratumoral heterogeneity, and immune response across cancersAlex Miranda, Phineas T. Hamilton, Allen W. Zhang, Swetansu Pattnaik, Etienne Becht, Artur Mezheyeuski, Jarle Bruun, Patrick Micke, Aurélien de Reynies, and Brad H. NelsonPNAS April 30, 2019 116 (18) 9020-9029; first published April 17, 2019. https://doi.org/10.1073/pnas.1818210116
- Open AccessCellular senescence in progenitor cells contributes to diminished remyelination potential in progressive multiple sclerosis
- From the Cover
Alexandra M. Nicaise, Laura J. Wagstaff, Cory M. Willis, Carolyn Paisie, Harshpreet Chandok, Paul Robson, Valentina Fossati, Anna Williams, and Stephen J. CrockerPNAS April 30, 2019 116 (18) 9030-9039; first published March 25, 2019. https://doi.org/10.1073/pnas.1818348116See companion article:
- New age for progressive multiple sclerosis- Apr 19, 2019
Microbiology
- You have accessMutations in the HIV-1 envelope glycoprotein can broadly rescue blocks at multiple steps in the virus replication cycleRachel Van Duyne, Lillian S. Kuo, Phuong Pham, Ken Fujii, and Eric O. FreedPNAS April 30, 2019 116 (18) 9040-9049; first published April 11, 2019. https://doi.org/10.1073/pnas.1820333116
Neuroscience
- Open AccessFunctional connectomics of affective and psychotic pathologyJustin T. Baker, Daniel G. Dillon, Lauren M. Patrick, Joshua L. Roffman, Roscoe O. Brady Jr., Diego A. Pizzagalli, Dost Öngür, and Avram J. HolmesPNAS April 30, 2019 116 (18) 9050-9059; first published April 15, 2019. https://doi.org/10.1073/pnas.1820780116
- You have accessCausal inference accounts for heading perception in the presence of object motionKalpana Dokka, Hyeshin Park, Michael Jansen, Gregory C. DeAngelis, and Dora E. AngelakiPNAS April 30, 2019 116 (18) 9060-9065; first published April 17, 2019. https://doi.org/10.1073/pnas.1820373116
- You have accessCompulsive drug use is associated with imbalance of orbitofrontal- and prelimbic-striatal circuits in punishment-resistant individualsYuzheng Hu, Betty Jo Salmeron, Irina N. Krasnova, Hong Gu, Hanbing Lu, Antonello Bonci, Jean L. Cadet, Elliot A. Stein, and Yihong YangPNAS April 30, 2019 116 (18) 9066-9071; first published April 15, 2019. https://doi.org/10.1073/pnas.1819978116
- You have accessModulation of fear generalization by the zona incertaArchana Venkataraman, Natalia Brody, Preethi Reddi, Jidong Guo, Donald Gordon Rainnie, and Brian George DiasPNAS April 30, 2019 116 (18) 9072-9077; first published April 9, 2019. https://doi.org/10.1073/pnas.1820541116
- Open AccessReduced default mode network functional connectivity in patients with recurrent major depressive disorderChao-Gan Yan, Xiao Chen, Le Li, Francisco Xavier Castellanos, Tong-Jian Bai, Qi-Jing Bo, Jun Cao, Guan-Mao Chen, Ning-Xuan Chen, Wei Chen, Chang Cheng, Yu-Qi Cheng, Xi-Long Cui, Jia Duan, Yi-Ru Fang, Qi-Yong Gong, Wen-Bin Guo, Zheng-Hua Hou, Lan Hu, Li Kuang, Feng Li, Kai-Ming Li, Tao Li, Yan-Song Liu, Zhe-Ning Liu, Yi-Cheng Long, Qing-Hua Luo, Hua-Qing Meng, Dai-Hui Peng, Hai-Tang Qiu, Jiang Qiu, Yue-Di Shen, Yu-Shu Shi, Chuan-Yue Wang, Fei Wang, Kai Wang, Li Wang, Xiang Wang, Ying Wang, Xiao-Ping Wu, Xin-Ran Wu, Chun-Ming Xie, Guang-Rong Xie, Hai-Yan Xie, Peng Xie, Xiu-Feng Xu, Hong Yang, Jian Yang, Jia-Shu Yao, Shu-Qiao Yao, Ying-Ying Yin, Yong-Gui Yuan, Ai-Xia Zhang, Hong Zhang, Ke-Rang Zhang, Lei Zhang, Zhi-Jun Zhang, Ru-Bai Zhou, Yi-Ting Zhou, Jun-Juan Zhu, Chao-Jie Zou, Tian-Mei Si, Xi-Nian Zuo, Jing-Ping Zhao, and Yu-Feng ZangPNAS April 30, 2019 116 (18) 9078-9083; first published April 12, 2019. https://doi.org/10.1073/pnas.1900390116
- You have accessIntrinsic planar polarity mechanisms influence the position-dependent regulation of synapse properties in inner hair cellsPhilippe Jean, Özge Demet Özçete, Basile Tarchini, and Tobias MoserPNAS April 30, 2019 116 (18) 9084-9093; first published April 11, 2019. https://doi.org/10.1073/pnas.1818358116
- You have accessDelta-secretase-cleaved Tau antagonizes TrkB neurotrophic signalings, mediating Alzheimer’s disease pathologiesJie Xiang, Zhi-Hao Wang, Eun Hee Ahn, Xia Liu, Shan-Ping Yu, Fredric P. Manfredsson, Ivette M. Sandoval, Gong Ju, Shengxi Wu, and Keqiang YePNAS April 30, 2019 116 (18) 9094-9102; first published April 19, 2019. https://doi.org/10.1073/pnas.1901348116
- You have accessHypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at single-cell resolutionJacob S. Heng, Amir Rattner, Genevieve L. Stein-O’Brien, Briana L. Winer, Bryan W. Jones, Hilary J. Vernon, Loyal A. Goff, and Jeremy NathansPNAS April 30, 2019 116 (18) 9103-9114; first published April 15, 2019. https://doi.org/10.1073/pnas.1821122116
- You have accessProtease-independent action of tissue plasminogen activator in brain plasticity and neurological recovery after ischemic strokeHongjian Pu, Yejie Shi, Lili Zhang, Zhengyu Lu, Qing Ye, Rehana K. Leak, Fei Xu, Shubei Ma, Hongfeng Mu, Zhishuo Wei, Na Xu, Yuguo Xia, Xiaoming Hu, T. Kevin Hitchens, Michael V. L. Bennett, and Jun ChenPNAS April 30, 2019 116 (18) 9115-9124; first published April 17, 2019. https://doi.org/10.1073/pnas.1821979116
Physiology
- You have accessConstitutive release of CPS1 in bile and its role as a protective cytokine during acute liver injuryMin-Jung Park, Louis G. D’Alecy, Michelle A. Anderson, Venkatesha Basrur, Yongjia Feng, Graham F. Brady, Dong-il Kim, Jun Wu, Alexey I. Nesvizhskii, Joerg Lahann, Nicholas W. Lukacs, Robert J. Fontana, and M. Bishr OmaryPNAS April 30, 2019 116 (18) 9125-9134; first published April 12, 2019. https://doi.org/10.1073/pnas.1822173116
Corrections
- You have accessCorrection for Drollette et al., Elevated levels of diesel range organic compounds in groundwater near Marcellus gas operations are derived from surface activitiesPNAS April 30, 2019 116 (18) 9135; first published April 22, 2019. https://doi.org/10.1073/pnas.1905353116
- You have accessCorrection for Khoddami et al., Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolutionPNAS April 30, 2019 116 (18) 9136; first published April 22, 2019. https://doi.org/10.1073/pnas.1905628116
- You have accessCorrection for Tang and Dubayah, Light-driven growth in Amazon evergreen forests explained by seasonal variations of vertical canopy structurePNAS April 30, 2019 116 (18) 9137; first published April 23, 2019. https://doi.org/10.1073/pnas.1905220116
Commentaries
See companion article:
See companion article: