Proceedings of the National Academy of Sciences: 116 (23)

New Research In

June 04, 2019; vol. 116 no. 23

This Week in PNAS

You have access
In This Issue
PNAS June 4, 2019 116 (23) 11079-11081; https://doi.org/10.1073/iti2319116

Inner Workings

An over-the-shoulder look at scientists at work.

You have access
Inner Workings: Family of protein fragments promises fresh view of Alzheimer's disease
Front Matter
Charlotte Schubert

PNAS June 4, 2019 116 (23) 11082-11084; https://doi.org/10.1073/pnas.1905886116

Commentaries

You have access
New progress on the zeta function: From old conjectures to a major breakthrough
Enrico Bombieri

PNAS June 4, 2019 116 (23) 11085-11086; first published May 23, 2019. https://doi.org/10.1073/pnas.1906804116
See companion article:
Jensen polynomials for the Riemann zeta function and other sequences
- May 21, 2019
You have access
Ancient medicinal plants of South America
Christine VanPool

PNAS June 4, 2019 116 (23) 11087-11089; first published May 21, 2019. https://doi.org/10.1073/pnas.1906805116
See companion article:
Chemical evidence for the use of multiple psychotropic plants in a 1,000-year-old ritual bundle from South America
- May 06, 2019
You have access
Predicting clinical outcome of therapy-resistant prostate cancer
Xin Ma and Jiaoti Huang

PNAS June 4, 2019 116 (23) 11090-11092; first published May 21, 2019. https://doi.org/10.1073/pnas.1906812116
See companion article:
Genomic correlates of clinical outcome in advanced prostate cancer
- May 06, 2019

Perspective

You have access
Microbial biospherics: The experimental study of ecosystem function and evolution
Matthias C. Rillig and Janis Antonovics

PNAS June 4, 2019 116 (23) 11093-11098; first published May 20, 2019. https://doi.org/10.1073/pnas.1904326116

Letters

You have access
Molecular models should not be published without the corresponding atomic coordinates
Stephen C. Graham, Bhushan Nagar, Gilbert G. Privé, and Janet E. Deane

PNAS June 4, 2019 116 (23) 11099-11100; https://doi.org/10.1073/pnas.1904409116
You have access
Reply to Graham et al.: In silico atomistic coordinates and molecular dynamics simulation trajectories of the glucocerebrosidase–saposin C complex
Raquel Romero, Tony Yuen, Maria I. New, Mone Zaidi, and Shozeb Haider

PNAS June 4, 2019 116 (23) 11101-11102; https://doi.org/10.1073/pnas.1905744116
See companion article:
Mechanism of glucocerebrosidase activation and dysfunction in Gaucher disease unraveled by molecular dynamics and deep learning
- Feb 26, 2019

Brief Reports

Open Access
Aberrant expression of select piRNA-pathway genes does not reactivate piRNA silencing in cancer cells
Pavol Genzor, Seth C. Cordts, Neha V. Bokil, and Astrid D. Haase

PNAS June 4, 2019 116 (23) 11111-11112; first published May 20, 2019. https://doi.org/10.1073/pnas.1904498116
Open Access
Functional cooperation of α-synuclein and VAMP2 in synaptic vesicle recycling
Jichao Sun, Lina Wang, Huan Bao, Sanjay Premi, Utpal Das, Edwin R. Chapman, and Subhojit Roy

PNAS June 4, 2019 116 (23) 11113-11115; first published May 20, 2019. https://doi.org/10.1073/pnas.1903049116
See companion article:
Synapsins regulate α-synuclein functions
- May 20, 2019
Open Access
Synapsins regulate α-synuclein functions
Merav Atias, Yaara Tevet, Jichao Sun, Alexandra Stavsky, Shani Tal, Joy Kahn, Subhojit Roy, and Daniel Gitler

PNAS June 4, 2019 116 (23) 11116-11118; first published May 20, 2019. https://doi.org/10.1073/pnas.1903054116
See companion article:
Functional cooperation of α-synuclein and VAMP2 in synaptic vesicle recycling
- May 20, 2019

Physical Sciences

Applied Mathematics
- You have access
  A mathematical theory of semantic development in deep neural networks
  Andrew M. Saxe, James L. McClelland, and Surya Ganguli
  
  PNAS June 4, 2019 116 (23) 11537-11546; first published May 17, 2019. https://doi.org/10.1073/pnas.1820226116
Applied Physical Sciences
- You have access
  Bacterial scattering in microfluidic crystal flows reveals giant active Taylor–Aris dispersion
  Amin Dehkharghani, Nicolas Waisbord, Jörn Dunkel, and Jeffrey S. Guasto
  
  PNAS June 4, 2019 116 (23) 11119-11124; first published May 16, 2019. https://doi.org/10.1073/pnas.1819613116
- You have access
  Self-organizing motors divide active liquid droplets
  Kimberly L. Weirich, Kinjal Dasbiswas, Thomas A. Witten, Suriyanarayanan Vaikuntanathan, and Margaret L. Gardel
  
  PNAS June 4, 2019 116 (23) 11125-11130; first published May 21, 2019. https://doi.org/10.1073/pnas.1814854116
- You have access
  Evolution of interlayer and intralayer magnetism in three atomically thin chromium trihalides
  Hyun Ho Kim, Bowen Yang, Siwen Li, Shengwei Jiang, Chenhao Jin, Zui Tao, George Nichols, Francois Sfigakis, Shazhou Zhong, Chenghe Li, Shangjie Tian, David G. Cory, Guo-Xing Miao, Jie Shan, Kin Fai Mak, Hechang Lei, Kai Sun, Liuyan Zhao, and Adam W. Tsen
  
  PNAS June 4, 2019 116 (23) 11131-11136; first published May 20, 2019. https://doi.org/10.1073/pnas.1902100116
- Open Access
  Optical edge detection based on high-efficiency dielectric metasurface
  Junxiao Zhou, Haoliang Qian, Ching-Fu Chen, Junxiang Zhao, Guangru Li, Qianyi Wu, Hailu Luo, Shuangchun Wen, and Zhaowei Liu
  
  PNAS June 4, 2019 116 (23) 11137-11140; first published May 17, 2019. https://doi.org/10.1073/pnas.1820636116
Astronomy
- You have access
  Machine learning reveals systematic accumulation of electric current in lead-up to solar flares
  Dattaraj B. Dhuri, Shravan M. Hanasoge, and Mark C. M. Cheung
  
  PNAS June 4, 2019 116 (23) 11141-11146; first published May 20, 2019. https://doi.org/10.1073/pnas.1820244116
Biophysics and Computational Biology
- You have access
  Ultrafast optical clearing method for three-dimensional imaging with cellular resolution
  Xinpei Zhu, Limeng Huang, Yao Zheng, Yanchun Song, Qiaoqi Xu, Jiahao Wang, Ke Si, Shumin Duan, and Wei Gong
  
  PNAS June 4, 2019 116 (23) 11480-11489; first published May 17, 2019. https://doi.org/10.1073/pnas.1819583116
Chemistry
- You have access
  Concepts and tools for mechanism and selectivity analysis in synthetic organic electrochemistry
  Cyrille Costentin and Jean-Michel Savéant
  
  PNAS June 4, 2019 116 (23) 11147-11152; first published May 17, 2019. https://doi.org/10.1073/pnas.1904439116
- You have access
  Crossing the bridge from molecular catalysis to a heterogenous electrode in electrocatalytic water oxidation
  Lei Wu, Animesh Nayak, Jing Shao, and Thomas J. Meyer
  
  PNAS June 4, 2019 116 (23) 11153-11158; first published May 16, 2019. https://doi.org/10.1073/pnas.1902455116
- You have access
  Spontaneous and directed symmetry breaking in the formation of chiral nanocrystals
  Uri Hananel, Assaf Ben-Moshe, Haim Diamant, and Gil Markovich
  
  PNAS June 4, 2019 116 (23) 11159-11164; first published May 16, 2019. https://doi.org/10.1073/pnas.1821923116
- You have access
  Microsecond and millisecond dynamics in the photosynthetic protein LHCSR1 observed by single-molecule correlation spectroscopy
  Toru Kondo, Jesse B. Gordon, Alberta Pinnola, Luca Dall’Osto, Roberto Bassi, and Gabriela S. Schlau-Cohen
  
  PNAS June 4, 2019 116 (23) 11247-11252; first published May 17, 2019. https://doi.org/10.1073/pnas.1821207116
- You have access
  Interrogating dense ligand chemical space with a forward-synthetic library
  Florent Chevillard, Silvia Stotani, Anna Karawajczyk, Stanimira Hristeva, Els Pardon, Jan Steyaert, Dimitrios Tzalis, and Peter Kolb
  
  PNAS June 4, 2019 116 (23) 11496-11501; first published May 21, 2019. https://doi.org/10.1073/pnas.1818718116
Earth, Atmospheric, and Planetary Sciences
- You have access
  Untangling the formation and liberation of water in the lunar regolith
  Cheng Zhu, Parker B. Crandall, Jeffrey J. Gillis-Davis, Hope A. Ishii, John P. Bradley, Laura M. Corley, and Ralf I. Kaiser
  
  PNAS June 4, 2019 116 (23) 11165-11170; first published May 20, 2019. https://doi.org/10.1073/pnas.1819600116
- You have access
  Mapping hydroxyl variability throughout the global remote troposphere via synthesis of airborne and satellite formaldehyde observations
  Glenn M. Wolfe, Julie M. Nicely, Jason M. St. Clair, Thomas F. Hanisco, Jin Liao, Luke D. Oman, William B. Brune, David Miller, Alexander Thames, Gonzalo González Abad, Thomas B. Ryerson, Chelsea R. Thompson, Jeff Peischl, Kathryn McKain, Colm Sweeney, Paul O. Wennberg, Michelle Kim, John D. Crounse, Samuel R. Hall, Kirk Ullmann, Glenn Diskin, Paul Bui, Cecilia Chang, and Jonathan Dean-Day
  
  PNAS June 4, 2019 116 (23) 11171-11180; first published May 20, 2019. https://doi.org/10.1073/pnas.1821661116
- You have access
  Circumventing kinetics in biogeochemical modeling
  Stilianos Louca, Mary I. Scranton, Gordon T. Taylor, Yrene M. Astor, Sean A. Crowe, and Michael Doebeli
  
  PNAS June 4, 2019 116 (23) 11329-11338; first published May 16, 2019. https://doi.org/10.1073/pnas.1819883116
Engineering
- You have access
  Stabilizing the metastable superhard material wurtzite boron nitride by three-dimensional networks of planar defects
  Chunlin Chen, Deqiang Yin, Takeharu Kato, Takashi Taniguchi, Kenji Watanabe, Xiuliang Ma, Hengqiang Ye, and Yuichi Ikuhara
  
  PNAS June 4, 2019 116 (23) 11181-11186; first published May 17, 2019. https://doi.org/10.1073/pnas.1902820116
Environmental Sciences
- You have access
  Climate change mitigation potential of carbon capture and utilization in the chemical industry
  From the Cover
  
  Arne Kätelhön, Raoul Meys, Sarah Deutz, Sangwon Suh, and André Bardow
  
  PNAS June 4, 2019 116 (23) 11187-11194; first published May 13, 2019. https://doi.org/10.1073/pnas.1821029116
- Open Access
  Ice sheet contributions to future sea-level rise from structured expert judgment
  Jonathan L. Bamber, Michael Oppenheimer, Robert E. Kopp, Willy P. Aspinall, and Roger M. Cooke
  
  PNAS June 4, 2019 116 (23) 11195-11200; first published May 20, 2019. https://doi.org/10.1073/pnas.1817205116
Mathematics
- Open Access
  Jensen polynomials for the Riemann zeta function and other sequences
  From the Cover
  
  Inaugural Article
  
  Michael Griffin, Ken Ono, Larry Rolen, and Don Zagier
  
  PNAS June 4, 2019 116 (23) 11103-11110; first published May 21, 2019. https://doi.org/10.1073/pnas.1902572116
  
  See companion article:
  New progress on the zeta function: From old conjectures to a major breakthrough
  - May 23, 2019
Physics
- Open Access
  Linear magnetoresistance in the low-field limit in density-wave materials
  Yejun Feng, Yishu Wang, D. M. Silevitch, J.-Q. Yan, Riki Kobayashi, Masato Hedo, Takao Nakama, Yoshichika Ōnuki, A. V. Suslov, B. Mihaila, P. B. Littlewood, and T. F. Rosenbaum
  
  PNAS June 4, 2019 116 (23) 11201-11206; first published April 11, 2019. https://doi.org/10.1073/pnas.1820092116

Biological Sciences

Agricultural Sciences
- You have access
  NAC-type transcription factors regulate accumulation of starch and protein in maize seeds
  Zhiyong Zhang, Jiaqiang Dong, Chen Ji, Yongrui Wu, and Joachim Messing
  
  PNAS June 4, 2019 116 (23) 11223-11228; first published May 20, 2019. https://doi.org/10.1073/pnas.1904995116
Biochemistry
- You have access
  Structure of full-length human phenylalanine hydroxylase in complex with tetrahydrobiopterin
  Marte Innselset Flydal, Martín Alcorlo-Pagés, Fredrik Gullaksen Johannessen, Siseth Martínez-Caballero, Lars Skjærven, Rafael Fernandez-Leiro, Aurora Martinez, and Juan A. Hermoso
  
  PNAS June 4, 2019 116 (23) 11229-11234; first published May 22, 2019. https://doi.org/10.1073/pnas.1902639116
- You have access
  Assembly of the complexes of oxidative phosphorylation triggers the remodeling of cardiolipin
  Yang Xu, Murari Anjaneyulu, Alec Donelian, Wenxi Yu, Miriam L. Greenberg, Mindong Ren, Edward Owusu-Ansah, and Michael Schlame
  
  PNAS June 4, 2019 116 (23) 11235-11240; first published May 20, 2019. https://doi.org/10.1073/pnas.1900890116
- You have access
  MmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamine
  Chih-Chia Su, Philip A. Klenotic, Jani Reddy Bolla, Georgiana E. Purdy, Carol V. Robinson, and Edward W. Yu
  
  PNAS June 4, 2019 116 (23) 11241-11246; first published May 21, 2019. https://doi.org/10.1073/pnas.1901346116
Biophysics and Computational Biology
- You have access
  Bacterial scattering in microfluidic crystal flows reveals giant active Taylor–Aris dispersion
  Amin Dehkharghani, Nicolas Waisbord, Jörn Dunkel, and Jeffrey S. Guasto
  
  PNAS June 4, 2019 116 (23) 11119-11124; first published May 16, 2019. https://doi.org/10.1073/pnas.1819613116
- You have access
  Self-organizing motors divide active liquid droplets
  Kimberly L. Weirich, Kinjal Dasbiswas, Thomas A. Witten, Suriyanarayanan Vaikuntanathan, and Margaret L. Gardel
  
  PNAS June 4, 2019 116 (23) 11125-11130; first published May 21, 2019. https://doi.org/10.1073/pnas.1814854116
- You have access
  Microsecond and millisecond dynamics in the photosynthetic protein LHCSR1 observed by single-molecule correlation spectroscopy
  Toru Kondo, Jesse B. Gordon, Alberta Pinnola, Luca Dall’Osto, Roberto Bassi, and Gabriela S. Schlau-Cohen
  
  PNAS June 4, 2019 116 (23) 11247-11252; first published May 17, 2019. https://doi.org/10.1073/pnas.1821207116
- You have access
  Molecular structure of an N-terminal phosphorylated β-amyloid fibril
  Zhi-Wen Hu, Liliya Vugmeyster, Dan Fai Au, Dmitry Ostrovsky, Yan Sun, and Wei Qiang
  
  PNAS June 4, 2019 116 (23) 11253-11258; first published May 16, 2019. https://doi.org/10.1073/pnas.1818530116
- You have access
  Design of self-assembly dipeptide hydrogels and machine learning via their chemical features
  Fei Li, Jinsong Han, Tian Cao, William Lam, Baoer Fan, Wen Tang, Sijie Chen, Kin Lam Fok, and Linxian Li
  
  PNAS June 4, 2019 116 (23) 11259-11264; first published May 20, 2019. https://doi.org/10.1073/pnas.1903376116
- You have access
  Substrate inhibition imposes fitness penalty at high protein stability
  Bharat V. Adkar, Sanchari Bhattacharyya, Amy I. Gilson, Wenli Zhang, and Eugene I. Shakhnovich
  
  PNAS June 4, 2019 116 (23) 11265-11274; first published May 16, 2019. https://doi.org/10.1073/pnas.1821447116
- You have access
  Consensus sequence design as a general strategy to create hyperstable, biologically active proteins
  Matt Sternke, Katherine W. Tripp, and Doug Barrick
  
  PNAS June 4, 2019 116 (23) 11275-11284; first published May 20, 2019. https://doi.org/10.1073/pnas.1816707116
Cell Biology
- You have access
  Muscle development and regeneration controlled by AUF1-mediated stage-specific degradation of fate-determining checkpoint mRNAs
  Dounia Abbadi, Ming Yang, Devon M. Chenette, John J. Andrews, and Robert J. Schneider
  
  PNAS June 4, 2019 116 (23) 11285-11290; first published May 21, 2019. https://doi.org/10.1073/pnas.1901165116
- You have access
  Chaperone-mediated reflux of secretory proteins to the cytosol during endoplasmic reticulum stress
  Aeid Igbaria, Philip I. Merksamer, Ala Trusina, Firehiwot Tilahun, Jeffrey R. Johnson, Onn Brandman, Nevan J. Krogan, Jonathan S. Weissman, and Feroz R. Papa
  
  PNAS June 4, 2019 116 (23) 11291-11298; first published May 17, 2019. https://doi.org/10.1073/pnas.1904516116
- You have access
  NURR1 activation in skeletal muscle controls systemic energy homeostasis
  Leonela Amoasii, Efrain Sanchez-Ortiz, Teppei Fujikawa, Joel K. Elmquist, Rhonda Bassel-Duby, and Eric N. Olson
  
  PNAS June 4, 2019 116 (23) 11299-11308; first published May 20, 2019. https://doi.org/10.1073/pnas.1902490116
- Open Access
  Role for polo-like kinase 4 in mediation of cytokinesis
  Michael F. Press, Bin Xie, Simon Davenport, Yu Zhou, Roberta Guzman, Garry P. Nolan, Neil O’Brien, Michael Palazzolo, Tak W. Mak, Joan S. Brugge, and Dennis J. Slamon
  
  PNAS June 4, 2019 116 (23) 11309-11318; first published May 16, 2019. https://doi.org/10.1073/pnas.1818820116
Ecology
- You have access
  Short-interval severe fire erodes the resilience of subalpine lodgepole pine forests
  Monica G. Turner, Kristin H. Braziunas, Winslow D. Hansen, and Brian J. Harvey
  
  PNAS June 4, 2019 116 (23) 11319-11328; first published May 20, 2019. https://doi.org/10.1073/pnas.1902841116
Environmental Sciences
- You have access
  Circumventing kinetics in biogeochemical modeling
  Stilianos Louca, Mary I. Scranton, Gordon T. Taylor, Yrene M. Astor, Sean A. Crowe, and Michael Doebeli
  
  PNAS June 4, 2019 116 (23) 11329-11338; first published May 16, 2019. https://doi.org/10.1073/pnas.1819883116
- Open Access
  Bone resorption and body reorganization during maturation induce maternal transfer of toxic metals in anguillid eels
  Marko Freese, Larissa Yokota Rizzo, Jan-Dag Pohlmann, Lasse Marohn, Paul Eckhard Witten, Felix Gremse, Stephan Rütten, Nihan Güvener, Sabrina Michael, Klaus Wysujack, Twan Lammers, Fabian Kiessling, Henner Hollert, Reinhold Hanel, and Markus Brinkmann
  
  PNAS June 4, 2019 116 (23) 11339-11344; first published May 13, 2019. https://doi.org/10.1073/pnas.1817738116
Evolution
- Open Access
  An ammonite trapped in Burmese amber
  From the Cover
  
  Tingting Yu, Richard Kelly, Lin Mu, Andrew Ross, Jim Kennedy, Pierre Broly, Fangyuan Xia, Haichun Zhang, Bo Wang, and David Dilcher
  
  PNAS June 4, 2019 116 (23) 11345-11350; first published May 13, 2019. https://doi.org/10.1073/pnas.1821292116
- Open Access
  A metaanalysis of bat phylogenetics and positive selection based on genomes and transcriptomes from 18 species
  John A. Hawkins, Maria E. Kaczmarek, Marcel A. Müller, Christian Drosten, William H. Press, and Sara L. Sawyer
  
  PNAS June 4, 2019 116 (23) 11351-11360; first published May 21, 2019. https://doi.org/10.1073/pnas.1814995116
- You have access
  Developmental integration and evolution of labile plasticity in a complex quantitative character in a multiperiodic environment
  Russell Lande
  
  PNAS June 4, 2019 116 (23) 11361-11369; first published May 16, 2019. https://doi.org/10.1073/pnas.1900528116
Genetics
- Open Access
  Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk
  Anthony S. Zannas, Meiwen Jia, Kathrin Hafner, Jens Baumert, Tobias Wiechmann, Julius C. Pape, Janine Arloth, Maik Ködel, Silvia Martinelli, Maria Roitman, Simone Röh, Andreas Haehle, Rebecca T. Emeny, Stella Iurato, Tania Carrillo-Roa, Jari Lahti, Katri Räikkönen, Johan G. Eriksson, Amanda J. Drake, Melanie Waldenberger, Simone Wahl, Sonja Kunze, Susanne Lucae, Bekh Bradley, Christian Gieger, Felix Hausch, Alicia K. Smith, Kerry J. Ressler, Bertram Müller-Myhsok, Karl-Heinz Ladwig, Theo Rein, Nils C. Gassen, and Elisabeth B. Binder
  
  PNAS June 4, 2019 116 (23) 11370-11379; first published May 21, 2019. https://doi.org/10.1073/pnas.1816847116
Immunology and Inflammation
- You have access
  Enhanced susceptibility to chemically induced colitis caused by excessive endosomal TLR signaling in LRBA-deficient mice
  Kuan-wen Wang, Xiaoming Zhan, William McAlpine, Zhao Zhang, Jin Huk Choi, Hexin Shi, Takuma Misawa, Tao Yue, Duanwu Zhang, Ying Wang, Sara Ludwig, Jamie Russell, Miao Tang, Xiaohong Li, Anne R. Murray, Eva Marie Y. Moresco, Emre E. Turer, and Bruce Beutler
  
  PNAS June 4, 2019 116 (23) 11380-11389; first published May 16, 2019. https://doi.org/10.1073/pnas.1901407116
Medical Sciences
- You have access
  Aneuploidy drives lethal progression in prostate cancer
  Konrad H. Stopsack, Charles A. Whittaker, Travis A. Gerke, Massimo Loda, Philip W. Kantoff, Lorelei A. Mucci, and Angelika Amon
  
  PNAS June 4, 2019 116 (23) 11390-11395; first published May 13, 2019. https://doi.org/10.1073/pnas.1902645116
- Open Access
  Protective role for the N-terminal domain of α-dystroglycan in Influenza A virus proliferation
  Jessica C. de Greef, Bram Slütter, Mary E. Anderson, Rebecca Hamlyn, Raul O’Campo Landa, Ellison J. McNutt, Yuji Hara, Lecia L. Pewe, David Venzke, Kiichiro Matsumura, Fumiaki Saito, John T. Harty, and Kevin P. Campbell
  
  PNAS June 4, 2019 116 (23) 11396-11401; first published May 16, 2019. https://doi.org/10.1073/pnas.1904493116
- You have access
  Positron emission tomography reporter gene strategy for use in the central nervous system
  Tom Haywood, Corinne Beinat, Gayatri Gowrishankar, Chirag B. Patel, Israt S. Alam, Surya Murty, and Sanjiv Sam Gambhir
  
  PNAS June 4, 2019 116 (23) 11402-11407; first published May 23, 2019. https://doi.org/10.1073/pnas.1901645116
- You have access
  TrxR1, Gsr, and oxidative stress determine hepatocellular carcinoma malignancy
  Michael R. McLoughlin, David J. Orlicky, Justin R. Prigge, Pushya Krishna, Emily A. Talago, Ian R. Cavigli, Sofi Eriksson, Colin G. Miller, Jean A. Kundert, Volkan I. Sayin, Rachel A. Sabol, Joshua Heinemann, Luke O. Brandenberger, Sonya V. Iverson, Brian Bothner, Thales Papagiannakopoulos, Colin T. Shearn, Elias S. J. Arnér, and Edward E. Schmidt
  
  PNAS June 4, 2019 116 (23) 11408-11417; first published May 16, 2019. https://doi.org/10.1073/pnas.1903244116
- Open Access
  Activation of unliganded FGF receptor by extracellular phosphate potentiates proteolytic protection of FGF23 by its O-glycosylation
  Yuichi Takashi, Hidetaka Kosako, Shun Sawatsubashi, Yuka Kinoshita, Nobuaki Ito, Maria K. Tsoumpra, Masaomi Nangaku, Masahiro Abe, Munehide Matsuhisa, Shigeaki Kato, Toshio Matsumoto, and Seiji Fukumoto
  
  PNAS June 4, 2019 116 (23) 11418-11427; first published May 16, 2019. https://doi.org/10.1073/pnas.1815166116
- Open Access
  Genomic correlates of clinical outcome in advanced prostate cancer
  From the Cover
  
  Wassim Abida, Joanna Cyrta, Glenn Heller, Davide Prandi, Joshua Armenia, Ilsa Coleman, Marcin Cieslik, Matteo Benelli, Dan Robinson, Eliezer M. Van Allen, Andrea Sboner, Tarcisio Fedrizzi, Juan Miguel Mosquera, Brian D. Robinson, Navonil De Sarkar, Lakshmi P. Kunju, Scott Tomlins, Yi Mi Wu, Daniel Nava Rodrigues, Massimo Loda, Anuradha Gopalan, Victor E. Reuter, Colin C. Pritchard, Joaquin Mateo, Diletta Bianchini, Susana Miranda, Suzanne Carreira, Pasquale Rescigno, Julie Filipenko, Jacob Vinson, Robert B. Montgomery, Himisha Beltran, Elisabeth I. Heath, Howard I. Scher, Philip W. Kantoff, Mary-Ellen Taplin, Nikolaus Schultz, Johann S. deBono, Francesca Demichelis, Peter S. Nelson, Mark A. Rubin, Arul M. Chinnaiyan, and Charles L. Sawyers
  
  PNAS June 4, 2019 116 (23) 11428-11436; first published May 6, 2019. https://doi.org/10.1073/pnas.1902651116
  
  See companion article:
  Predicting clinical outcome of therapy-resistant prostate cancer
  - May 21, 2019
- You have access
  Estrogen receptor signaling is reprogrammed during breast tumorigenesis
  David Chi, Hari Singhal, Lewyn Li, Tengfei Xiao, Weihan Liu, Matthew Pun, Rinath Jeselsohn, Housheng He, Elgene Lim, Raga Vadhi, Prakash Rao, Henry Long, Judy Garber, and Myles Brown
  
  PNAS June 4, 2019 116 (23) 11437-11443; first published May 20, 2019. https://doi.org/10.1073/pnas.1819155116
- You have access
  A human organoid system that self-organizes to recapitulate growth and differentiation of a benign mammary tumor
  Stefan Florian, Yoshiko Iwamoto, Margaret Coughlin, Ralph Weissleder, and Timothy J. Mitchison
  
  PNAS June 4, 2019 116 (23) 11444-11453; first published May 17, 2019. https://doi.org/10.1073/pnas.1702372116
Microbiology
- Open Access
  Systematic evasion of the restriction-modification barrier in bacteria
  Christopher D. Johnston, Sean L. Cotton, Susan R. Rittling, Jacqueline R. Starr, Gary G. Borisy, Floyd E. Dewhirst, and Katherine P. Lemon
  
  PNAS June 4, 2019 116 (23) 11454-11459; first published May 16, 2019. https://doi.org/10.1073/pnas.1820256116
- You have access
  A glycan shield on chimpanzee CD4 protects against infection by primate lentiviruses (HIV/SIV)
  Cody J. Warren, Nicholas R. Meyerson, Alex C. Stabell, Will T. Fattor, Gregory K. Wilkerson, and Sara L. Sawyer
  
  PNAS June 4, 2019 116 (23) 11460-11469; first published May 21, 2019. https://doi.org/10.1073/pnas.1813909116
- You have access
  Structural and functional analyses of the N-terminal domain of the A subunit of a Bacillus megaterium spore germinant receptor
  Yunfeng Li, Kai Jin, Abigail Perez-Valdespino, Kyle Federkiewicz, Andrew Davis, Mark W. Maciejewski, Peter Setlow, and Bing Hao
  
  PNAS June 4, 2019 116 (23) 11470-11479; first published May 21, 2019. https://doi.org/10.1073/pnas.1903675116
Neuroscience
- You have access
  Ultrafast optical clearing method for three-dimensional imaging with cellular resolution
  Xinpei Zhu, Limeng Huang, Yao Zheng, Yanchun Song, Qiaoqi Xu, Jiahao Wang, Ke Si, Shumin Duan, and Wei Gong
  
  PNAS June 4, 2019 116 (23) 11480-11489; first published May 17, 2019. https://doi.org/10.1073/pnas.1819583116
- You have access
  In vivo evidence for dysregulation of mGluR5 as a biomarker of suicidal ideation
  Margaret T. Davis, Ansel Hillmer, Sophie E. Holmes, Robert H. Pietrzak, Nicole DellaGioia, Nabeel Nabulsi, David Matuskey, Gustavo A. Angarita, Richard E. Carson, John H. Krystal, and Irina Esterlis
  
  PNAS June 4, 2019 116 (23) 11490-11495; first published May 13, 2019. https://doi.org/10.1073/pnas.1818871116
Pharmacology
- You have access
  Interrogating dense ligand chemical space with a forward-synthetic library
  Florent Chevillard, Silvia Stotani, Anna Karawajczyk, Stanimira Hristeva, Els Pardon, Jan Steyaert, Dimitrios Tzalis, and Peter Kolb
  
  PNAS June 4, 2019 116 (23) 11496-11501; first published May 21, 2019. https://doi.org/10.1073/pnas.1818718116
Physiology
- You have access
  Cardiac myosin activation with 2-deoxy-ATP via increased electrostatic interactions with actin
  Joseph D. Powers, Chen-Ching Yuan, Kimberly J. McCabe, Jason D. Murray, Matthew Carter Childers, Galina V. Flint, Farid Moussavi-Harami, Saffie Mohran, Romi Castillo, Carla Zuzek, Weikang Ma, Valerie Daggett, Andrew D. McCulloch, Thomas C. Irving, and Michael Regnier
  
  PNAS June 4, 2019 116 (23) 11502-11507; first published May 20, 2019. https://doi.org/10.1073/pnas.1905028116
- You have access
  Human nonvisual opsin 3 regulates pigmentation of epidermal melanocytes through functional interaction with melanocortin 1 receptor
  Rana N. Ozdeslik, Lauren E. Olinski, Melissa M. Trieu, Daniel D. Oprian, and Elena Oancea
  
  PNAS June 4, 2019 116 (23) 11508-11517; first published May 16, 2019. https://doi.org/10.1073/pnas.1902825116
Plant Biology
- Open Access
  Alternative outlets for sustaining photosynthetic electron transport during dark-to-light transitions
  Shai Saroussi, Devin A. J. Karns, Dylan C. Thomas, Clayton Bloszies, Oliver Fiehn, Matthew C. Posewitz, and Arthur R. Grossman
  
  PNAS June 4, 2019 116 (23) 11518-11527; first published May 17, 2019. https://doi.org/10.1073/pnas.1903185116
- Open Access
  Casein kinase 1 family regulates PRR5 and TOC1 in the Arabidopsis circadian clock
  Takahiro N. Uehara, Yoshiyuki Mizutani, Keiko Kuwata, Tsuyoshi Hirota, Ayato Sato, Junya Mizoi, Saori Takao, Hiromi Matsuo, Takamasa Suzuki, Shogo Ito, Ami N. Saito, Taeko Nishiwaki-Ohkawa, Kazuko Yamaguchi-Shinozaki, Takashi Yoshimura, Steve A. Kay, Kenichiro Itami, Toshinori Kinoshita, Junichiro Yamaguchi, and Norihito Nakamichi
  
  PNAS June 4, 2019 116 (23) 11528-11536; first published May 16, 2019. https://doi.org/10.1073/pnas.1903357116
Psychological and Cognitive Sciences
- You have access
  A mathematical theory of semantic development in deep neural networks
  Andrew M. Saxe, James L. McClelland, and Surya Ganguli
  
  PNAS June 4, 2019 116 (23) 11537-11546; first published May 17, 2019. https://doi.org/10.1073/pnas.1820226116
- You have access
  Negative emotional contagion and cognitive bias in common ravens (Corvus corax)
  Jessie E. C. Adriaense, Jordan S. Martin, Martina Schiestl, Claus Lamm, and Thomas Bugnyar
  
  PNAS June 4, 2019 116 (23) 11547-11552; first published May 20, 2019. https://doi.org/10.1073/pnas.1817066116
  
  See companion article:
  Reply to Vonk: Disentangling emotional contagion from its underlying causes
  - Aug 20, 2019

Correction

You have access
Correction for Kröger et al., Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells
PNAS June 4, 2019 116 (23) 11553-11554; first published May 28, 2019. https://doi.org/10.1073/pnas.1907473116

Main menu

User menu

Search

New Research In

Physical Sciences

Featured Portals

Articles by Topic

Social Sciences

Featured Portals

Articles by Topic

Biological Sciences

Featured Portals

Articles by Topic

Table of Contents

See companion article:

See companion article:

See companion article:

See companion article:

Brief Reports

See companion article:

See companion article:

Physical Sciences

See companion article:

Social Sciences

See companion article:

See companion article:

See companion article:

Biological Sciences

See companion article:

See companion article:

Browse PNAS issues

In this issue

Jump to

Articles

PNAS Portals

Information