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Table of Contents
June 04, 2019; vol. 116 no. 23
This Week in PNAS
Inner Workings
An over-the-shoulder look at scientists at work.
- You have accessInner Workings: Family of protein fragments promises fresh view of Alzheimer's disease
- Front Matter
Charlotte Schubert
Perspective
- You have accessMicrobial biospherics: The experimental study of ecosystem function and evolutionMatthias C. Rillig and Janis AntonovicsPNAS June 4, 2019 116 (23) 11093-11098; first published May 20, 2019. https://doi.org/10.1073/pnas.1904326116
Letters
- You have accessMolecular models should not be published without the corresponding atomic coordinatesStephen C. Graham, Bhushan Nagar, Gilbert G. Privé, and Janet E. Deane
- You have accessReply to Graham et al.: In silico atomistic coordinates and molecular dynamics simulation trajectories of the glucocerebrosidase–saposin C complexRaquel Romero, Tony Yuen, Maria I. New, Mone Zaidi, and Shozeb Haider
See companion article:
Brief Reports
- Open AccessAberrant expression of select piRNA-pathway genes does not reactivate piRNA silencing in cancer cellsPavol Genzor, Seth C. Cordts, Neha V. Bokil, and Astrid D. HaasePNAS June 4, 2019 116 (23) 11111-11112; first published May 20, 2019. https://doi.org/10.1073/pnas.1904498116
- Open AccessFunctional cooperation of α-synuclein and VAMP2 in synaptic vesicle recyclingJichao Sun, Lina Wang, Huan Bao, Sanjay Premi, Utpal Das, Edwin R. Chapman, and Subhojit RoyPNAS June 4, 2019 116 (23) 11113-11115; first published May 20, 2019. https://doi.org/10.1073/pnas.1903049116
See companion article:
- Synapsins regulate α-synuclein functions- May 20, 2019
- Open AccessSynapsins regulate α-synuclein functionsMerav Atias, Yaara Tevet, Jichao Sun, Alexandra Stavsky, Shani Tal, Joy Kahn, Subhojit Roy, and Daniel GitlerPNAS June 4, 2019 116 (23) 11116-11118; first published May 20, 2019. https://doi.org/10.1073/pnas.1903054116
See companion article:
Physical Sciences
Applied Mathematics
- You have accessA mathematical theory of semantic development in deep neural networksAndrew M. Saxe, James L. McClelland, and Surya GanguliPNAS June 4, 2019 116 (23) 11537-11546; first published May 17, 2019. https://doi.org/10.1073/pnas.1820226116
Applied Physical Sciences
- You have accessBacterial scattering in microfluidic crystal flows reveals giant active Taylor–Aris dispersionAmin Dehkharghani, Nicolas Waisbord, Jörn Dunkel, and Jeffrey S. GuastoPNAS June 4, 2019 116 (23) 11119-11124; first published May 16, 2019. https://doi.org/10.1073/pnas.1819613116
- You have accessSelf-organizing motors divide active liquid dropletsKimberly L. Weirich, Kinjal Dasbiswas, Thomas A. Witten, Suriyanarayanan Vaikuntanathan, and Margaret L. GardelPNAS June 4, 2019 116 (23) 11125-11130; first published May 21, 2019. https://doi.org/10.1073/pnas.1814854116
- You have accessEvolution of interlayer and intralayer magnetism in three atomically thin chromium trihalidesHyun Ho Kim, Bowen Yang, Siwen Li, Shengwei Jiang, Chenhao Jin, Zui Tao, George Nichols, Francois Sfigakis, Shazhou Zhong, Chenghe Li, Shangjie Tian, David G. Cory, Guo-Xing Miao, Jie Shan, Kin Fai Mak, Hechang Lei, Kai Sun, Liuyan Zhao, and Adam W. TsenPNAS June 4, 2019 116 (23) 11131-11136; first published May 20, 2019. https://doi.org/10.1073/pnas.1902100116
- Open AccessOptical edge detection based on high-efficiency dielectric metasurfaceJunxiao Zhou, Haoliang Qian, Ching-Fu Chen, Junxiang Zhao, Guangru Li, Qianyi Wu, Hailu Luo, Shuangchun Wen, and Zhaowei LiuPNAS June 4, 2019 116 (23) 11137-11140; first published May 17, 2019. https://doi.org/10.1073/pnas.1820636116
Astronomy
- You have accessMachine learning reveals systematic accumulation of electric current in lead-up to solar flaresDattaraj B. Dhuri, Shravan M. Hanasoge, and Mark C. M. CheungPNAS June 4, 2019 116 (23) 11141-11146; first published May 20, 2019. https://doi.org/10.1073/pnas.1820244116
Biophysics and Computational Biology
- You have accessUltrafast optical clearing method for three-dimensional imaging with cellular resolutionXinpei Zhu, Limeng Huang, Yao Zheng, Yanchun Song, Qiaoqi Xu, Jiahao Wang, Ke Si, Shumin Duan, and Wei GongPNAS June 4, 2019 116 (23) 11480-11489; first published May 17, 2019. https://doi.org/10.1073/pnas.1819583116
Chemistry
- You have accessConcepts and tools for mechanism and selectivity analysis in synthetic organic electrochemistryCyrille Costentin and Jean-Michel SavéantPNAS June 4, 2019 116 (23) 11147-11152; first published May 17, 2019. https://doi.org/10.1073/pnas.1904439116
- You have accessCrossing the bridge from molecular catalysis to a heterogenous electrode in electrocatalytic water oxidationLei Wu, Animesh Nayak, Jing Shao, and Thomas J. MeyerPNAS June 4, 2019 116 (23) 11153-11158; first published May 16, 2019. https://doi.org/10.1073/pnas.1902455116
- You have accessSpontaneous and directed symmetry breaking in the formation of chiral nanocrystalsUri Hananel, Assaf Ben-Moshe, Haim Diamant, and Gil MarkovichPNAS June 4, 2019 116 (23) 11159-11164; first published May 16, 2019. https://doi.org/10.1073/pnas.1821923116
- You have accessMicrosecond and millisecond dynamics in the photosynthetic protein LHCSR1 observed by single-molecule correlation spectroscopyToru Kondo, Jesse B. Gordon, Alberta Pinnola, Luca Dall’Osto, Roberto Bassi, and Gabriela S. Schlau-CohenPNAS June 4, 2019 116 (23) 11247-11252; first published May 17, 2019. https://doi.org/10.1073/pnas.1821207116
- You have accessInterrogating dense ligand chemical space with a forward-synthetic libraryFlorent Chevillard, Silvia Stotani, Anna Karawajczyk, Stanimira Hristeva, Els Pardon, Jan Steyaert, Dimitrios Tzalis, and Peter KolbPNAS June 4, 2019 116 (23) 11496-11501; first published May 21, 2019. https://doi.org/10.1073/pnas.1818718116
Earth, Atmospheric, and Planetary Sciences
- You have accessUntangling the formation and liberation of water in the lunar regolithCheng Zhu, Parker B. Crandall, Jeffrey J. Gillis-Davis, Hope A. Ishii, John P. Bradley, Laura M. Corley, and Ralf I. KaiserPNAS June 4, 2019 116 (23) 11165-11170; first published May 20, 2019. https://doi.org/10.1073/pnas.1819600116
- You have accessMapping hydroxyl variability throughout the global remote troposphere via synthesis of airborne and satellite formaldehyde observationsGlenn M. Wolfe, Julie M. Nicely, Jason M. St. Clair, Thomas F. Hanisco, Jin Liao, Luke D. Oman, William B. Brune, David Miller, Alexander Thames, Gonzalo González Abad, Thomas B. Ryerson, Chelsea R. Thompson, Jeff Peischl, Kathryn McKain, Colm Sweeney, Paul O. Wennberg, Michelle Kim, John D. Crounse, Samuel R. Hall, Kirk Ullmann, Glenn Diskin, Paul Bui, Cecilia Chang, and Jonathan Dean-DayPNAS June 4, 2019 116 (23) 11171-11180; first published May 20, 2019. https://doi.org/10.1073/pnas.1821661116
- You have accessCircumventing kinetics in biogeochemical modelingStilianos Louca, Mary I. Scranton, Gordon T. Taylor, Yrene M. Astor, Sean A. Crowe, and Michael DoebeliPNAS June 4, 2019 116 (23) 11329-11338; first published May 16, 2019. https://doi.org/10.1073/pnas.1819883116
Engineering
- You have accessStabilizing the metastable superhard material wurtzite boron nitride by three-dimensional networks of planar defectsChunlin Chen, Deqiang Yin, Takeharu Kato, Takashi Taniguchi, Kenji Watanabe, Xiuliang Ma, Hengqiang Ye, and Yuichi IkuharaPNAS June 4, 2019 116 (23) 11181-11186; first published May 17, 2019. https://doi.org/10.1073/pnas.1902820116
Environmental Sciences
- You have accessClimate change mitigation potential of carbon capture and utilization in the chemical industry
- From the Cover
Arne Kätelhön, Raoul Meys, Sarah Deutz, Sangwon Suh, and André BardowPNAS June 4, 2019 116 (23) 11187-11194; first published May 13, 2019. https://doi.org/10.1073/pnas.1821029116 - Open AccessIce sheet contributions to future sea-level rise from structured expert judgmentJonathan L. Bamber, Michael Oppenheimer, Robert E. Kopp, Willy P. Aspinall, and Roger M. CookePNAS June 4, 2019 116 (23) 11195-11200; first published May 20, 2019. https://doi.org/10.1073/pnas.1817205116
Mathematics
- Open AccessJensen polynomials for the Riemann zeta function and other sequences
- From the Cover
- Inaugural Article
Michael Griffin, Ken Ono, Larry Rolen, and Don ZagierPNAS June 4, 2019 116 (23) 11103-11110; first published May 21, 2019. https://doi.org/10.1073/pnas.1902572116See companion article:
Physics
- Open AccessLinear magnetoresistance in the low-field limit in density-wave materialsYejun Feng, Yishu Wang, D. M. Silevitch, J.-Q. Yan, Riki Kobayashi, Masato Hedo, Takao Nakama, Yoshichika Ōnuki, A. V. Suslov, B. Mihaila, P. B. Littlewood, and T. F. RosenbaumPNAS June 4, 2019 116 (23) 11201-11206; first published April 11, 2019. https://doi.org/10.1073/pnas.1820092116
Social Sciences
Anthropology
- You have accessChemical evidence for the use of multiple psychotropic plants in a 1,000-year-old ritual bundle from South America
- From the Cover
Melanie J. Miller, Juan Albarracin-Jordan, Christine Moore, and José M. CaprilesPNAS June 4, 2019 116 (23) 11207-11212; first published May 6, 2019. https://doi.org/10.1073/pnas.1902174116See companion article:
- Ancient medicinal plants of South America- May 21, 2019
Psychological and Cognitive Sciences
- You have accessKnowledge of animal appearance among sighted and blind adultsJudy S. Kim, Giulia V. Elli, and Marina BednyPNAS June 4, 2019 116 (23) 11213-11222; first published May 21, 2019. https://doi.org/10.1073/pnas.1900952116
- You have accessIn vivo evidence for dysregulation of mGluR5 as a biomarker of suicidal ideationMargaret T. Davis, Ansel Hillmer, Sophie E. Holmes, Robert H. Pietrzak, Nicole DellaGioia, Nabeel Nabulsi, David Matuskey, Gustavo A. Angarita, Richard E. Carson, John H. Krystal, and Irina EsterlisPNAS June 4, 2019 116 (23) 11490-11495; first published May 13, 2019. https://doi.org/10.1073/pnas.1818871116
- You have accessNegative emotional contagion and cognitive bias in common ravens (Corvus corax)Jessie E. C. Adriaense, Jordan S. Martin, Martina Schiestl, Claus Lamm, and Thomas BugnyarPNAS June 4, 2019 116 (23) 11547-11552; first published May 20, 2019. https://doi.org/10.1073/pnas.1817066116
See companion article:
Sustainability Science
- You have accessClimate change mitigation potential of carbon capture and utilization in the chemical industry
- From the Cover
Arne Kätelhön, Raoul Meys, Sarah Deutz, Sangwon Suh, and André BardowPNAS June 4, 2019 116 (23) 11187-11194; first published May 13, 2019. https://doi.org/10.1073/pnas.1821029116
Biological Sciences
Agricultural Sciences
- You have accessNAC-type transcription factors regulate accumulation of starch and protein in maize seedsZhiyong Zhang, Jiaqiang Dong, Chen Ji, Yongrui Wu, and Joachim MessingPNAS June 4, 2019 116 (23) 11223-11228; first published May 20, 2019. https://doi.org/10.1073/pnas.1904995116
Biochemistry
- You have accessStructure of full-length human phenylalanine hydroxylase in complex with tetrahydrobiopterinMarte Innselset Flydal, Martín Alcorlo-Pagés, Fredrik Gullaksen Johannessen, Siseth Martínez-Caballero, Lars Skjærven, Rafael Fernandez-Leiro, Aurora Martinez, and Juan A. HermosoPNAS June 4, 2019 116 (23) 11229-11234; first published May 22, 2019. https://doi.org/10.1073/pnas.1902639116
- You have accessAssembly of the complexes of oxidative phosphorylation triggers the remodeling of cardiolipinYang Xu, Murari Anjaneyulu, Alec Donelian, Wenxi Yu, Miriam L. Greenberg, Mindong Ren, Edward Owusu-Ansah, and Michael SchlamePNAS June 4, 2019 116 (23) 11235-11240; first published May 20, 2019. https://doi.org/10.1073/pnas.1900890116
- You have accessMmpL3 is a lipid transporter that binds trehalose monomycolate and phosphatidylethanolamineChih-Chia Su, Philip A. Klenotic, Jani Reddy Bolla, Georgiana E. Purdy, Carol V. Robinson, and Edward W. YuPNAS June 4, 2019 116 (23) 11241-11246; first published May 21, 2019. https://doi.org/10.1073/pnas.1901346116
Biophysics and Computational Biology
- You have accessBacterial scattering in microfluidic crystal flows reveals giant active Taylor–Aris dispersionAmin Dehkharghani, Nicolas Waisbord, Jörn Dunkel, and Jeffrey S. GuastoPNAS June 4, 2019 116 (23) 11119-11124; first published May 16, 2019. https://doi.org/10.1073/pnas.1819613116
- You have accessSelf-organizing motors divide active liquid dropletsKimberly L. Weirich, Kinjal Dasbiswas, Thomas A. Witten, Suriyanarayanan Vaikuntanathan, and Margaret L. GardelPNAS June 4, 2019 116 (23) 11125-11130; first published May 21, 2019. https://doi.org/10.1073/pnas.1814854116
- You have accessMicrosecond and millisecond dynamics in the photosynthetic protein LHCSR1 observed by single-molecule correlation spectroscopyToru Kondo, Jesse B. Gordon, Alberta Pinnola, Luca Dall’Osto, Roberto Bassi, and Gabriela S. Schlau-CohenPNAS June 4, 2019 116 (23) 11247-11252; first published May 17, 2019. https://doi.org/10.1073/pnas.1821207116
- You have accessMolecular structure of an N-terminal phosphorylated β-amyloid fibrilZhi-Wen Hu, Liliya Vugmeyster, Dan Fai Au, Dmitry Ostrovsky, Yan Sun, and Wei QiangPNAS June 4, 2019 116 (23) 11253-11258; first published May 16, 2019. https://doi.org/10.1073/pnas.1818530116
- You have accessDesign of self-assembly dipeptide hydrogels and machine learning via their chemical featuresFei Li, Jinsong Han, Tian Cao, William Lam, Baoer Fan, Wen Tang, Sijie Chen, Kin Lam Fok, and Linxian LiPNAS June 4, 2019 116 (23) 11259-11264; first published May 20, 2019. https://doi.org/10.1073/pnas.1903376116
- You have accessSubstrate inhibition imposes fitness penalty at high protein stabilityBharat V. Adkar, Sanchari Bhattacharyya, Amy I. Gilson, Wenli Zhang, and Eugene I. ShakhnovichPNAS June 4, 2019 116 (23) 11265-11274; first published May 16, 2019. https://doi.org/10.1073/pnas.1821447116
- You have accessConsensus sequence design as a general strategy to create hyperstable, biologically active proteinsMatt Sternke, Katherine W. Tripp, and Doug BarrickPNAS June 4, 2019 116 (23) 11275-11284; first published May 20, 2019. https://doi.org/10.1073/pnas.1816707116
Cell Biology
- You have accessMuscle development and regeneration controlled by AUF1-mediated stage-specific degradation of fate-determining checkpoint mRNAsDounia Abbadi, Ming Yang, Devon M. Chenette, John J. Andrews, and Robert J. SchneiderPNAS June 4, 2019 116 (23) 11285-11290; first published May 21, 2019. https://doi.org/10.1073/pnas.1901165116
- You have accessChaperone-mediated reflux of secretory proteins to the cytosol during endoplasmic reticulum stressAeid Igbaria, Philip I. Merksamer, Ala Trusina, Firehiwot Tilahun, Jeffrey R. Johnson, Onn Brandman, Nevan J. Krogan, Jonathan S. Weissman, and Feroz R. PapaPNAS June 4, 2019 116 (23) 11291-11298; first published May 17, 2019. https://doi.org/10.1073/pnas.1904516116
- You have accessNURR1 activation in skeletal muscle controls systemic energy homeostasisLeonela Amoasii, Efrain Sanchez-Ortiz, Teppei Fujikawa, Joel K. Elmquist, Rhonda Bassel-Duby, and Eric N. OlsonPNAS June 4, 2019 116 (23) 11299-11308; first published May 20, 2019. https://doi.org/10.1073/pnas.1902490116
- Open AccessRole for polo-like kinase 4 in mediation of cytokinesisMichael F. Press, Bin Xie, Simon Davenport, Yu Zhou, Roberta Guzman, Garry P. Nolan, Neil O’Brien, Michael Palazzolo, Tak W. Mak, Joan S. Brugge, and Dennis J. SlamonPNAS June 4, 2019 116 (23) 11309-11318; first published May 16, 2019. https://doi.org/10.1073/pnas.1818820116
Ecology
- You have accessShort-interval severe fire erodes the resilience of subalpine lodgepole pine forestsMonica G. Turner, Kristin H. Braziunas, Winslow D. Hansen, and Brian J. HarveyPNAS June 4, 2019 116 (23) 11319-11328; first published May 20, 2019. https://doi.org/10.1073/pnas.1902841116
Environmental Sciences
- You have accessCircumventing kinetics in biogeochemical modelingStilianos Louca, Mary I. Scranton, Gordon T. Taylor, Yrene M. Astor, Sean A. Crowe, and Michael DoebeliPNAS June 4, 2019 116 (23) 11329-11338; first published May 16, 2019. https://doi.org/10.1073/pnas.1819883116
- Open AccessBone resorption and body reorganization during maturation induce maternal transfer of toxic metals in anguillid eelsMarko Freese, Larissa Yokota Rizzo, Jan-Dag Pohlmann, Lasse Marohn, Paul Eckhard Witten, Felix Gremse, Stephan Rütten, Nihan Güvener, Sabrina Michael, Klaus Wysujack, Twan Lammers, Fabian Kiessling, Henner Hollert, Reinhold Hanel, and Markus BrinkmannPNAS June 4, 2019 116 (23) 11339-11344; first published May 13, 2019. https://doi.org/10.1073/pnas.1817738116
Evolution
- Open AccessAn ammonite trapped in Burmese amber
- From the Cover
Tingting Yu, Richard Kelly, Lin Mu, Andrew Ross, Jim Kennedy, Pierre Broly, Fangyuan Xia, Haichun Zhang, Bo Wang, and David DilcherPNAS June 4, 2019 116 (23) 11345-11350; first published May 13, 2019. https://doi.org/10.1073/pnas.1821292116 - Open AccessA metaanalysis of bat phylogenetics and positive selection based on genomes and transcriptomes from 18 speciesJohn A. Hawkins, Maria E. Kaczmarek, Marcel A. Müller, Christian Drosten, William H. Press, and Sara L. SawyerPNAS June 4, 2019 116 (23) 11351-11360; first published May 21, 2019. https://doi.org/10.1073/pnas.1814995116
- You have accessDevelopmental integration and evolution of labile plasticity in a complex quantitative character in a multiperiodic environmentRussell LandePNAS June 4, 2019 116 (23) 11361-11369; first published May 16, 2019. https://doi.org/10.1073/pnas.1900528116
Genetics
- Open AccessEpigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular riskAnthony S. Zannas, Meiwen Jia, Kathrin Hafner, Jens Baumert, Tobias Wiechmann, Julius C. Pape, Janine Arloth, Maik Ködel, Silvia Martinelli, Maria Roitman, Simone Röh, Andreas Haehle, Rebecca T. Emeny, Stella Iurato, Tania Carrillo-Roa, Jari Lahti, Katri Räikkönen, Johan G. Eriksson, Amanda J. Drake, Melanie Waldenberger, Simone Wahl, Sonja Kunze, Susanne Lucae, Bekh Bradley, Christian Gieger, Felix Hausch, Alicia K. Smith, Kerry J. Ressler, Bertram Müller-Myhsok, Karl-Heinz Ladwig, Theo Rein, Nils C. Gassen, and Elisabeth B. BinderPNAS June 4, 2019 116 (23) 11370-11379; first published May 21, 2019. https://doi.org/10.1073/pnas.1816847116
Immunology and Inflammation
- You have accessEnhanced susceptibility to chemically induced colitis caused by excessive endosomal TLR signaling in LRBA-deficient miceKuan-wen Wang, Xiaoming Zhan, William McAlpine, Zhao Zhang, Jin Huk Choi, Hexin Shi, Takuma Misawa, Tao Yue, Duanwu Zhang, Ying Wang, Sara Ludwig, Jamie Russell, Miao Tang, Xiaohong Li, Anne R. Murray, Eva Marie Y. Moresco, Emre E. Turer, and Bruce BeutlerPNAS June 4, 2019 116 (23) 11380-11389; first published May 16, 2019. https://doi.org/10.1073/pnas.1901407116
Medical Sciences
- You have accessAneuploidy drives lethal progression in prostate cancerKonrad H. Stopsack, Charles A. Whittaker, Travis A. Gerke, Massimo Loda, Philip W. Kantoff, Lorelei A. Mucci, and Angelika AmonPNAS June 4, 2019 116 (23) 11390-11395; first published May 13, 2019. https://doi.org/10.1073/pnas.1902645116
- Open AccessProtective role for the N-terminal domain of α-dystroglycan in Influenza A virus proliferationJessica C. de Greef, Bram Slütter, Mary E. Anderson, Rebecca Hamlyn, Raul O’Campo Landa, Ellison J. McNutt, Yuji Hara, Lecia L. Pewe, David Venzke, Kiichiro Matsumura, Fumiaki Saito, John T. Harty, and Kevin P. CampbellPNAS June 4, 2019 116 (23) 11396-11401; first published May 16, 2019. https://doi.org/10.1073/pnas.1904493116
- You have accessPositron emission tomography reporter gene strategy for use in the central nervous systemTom Haywood, Corinne Beinat, Gayatri Gowrishankar, Chirag B. Patel, Israt S. Alam, Surya Murty, and Sanjiv Sam GambhirPNAS June 4, 2019 116 (23) 11402-11407; first published May 23, 2019. https://doi.org/10.1073/pnas.1901645116
- You have accessTrxR1, Gsr, and oxidative stress determine hepatocellular carcinoma malignancyMichael R. McLoughlin, David J. Orlicky, Justin R. Prigge, Pushya Krishna, Emily A. Talago, Ian R. Cavigli, Sofi Eriksson, Colin G. Miller, Jean A. Kundert, Volkan I. Sayin, Rachel A. Sabol, Joshua Heinemann, Luke O. Brandenberger, Sonya V. Iverson, Brian Bothner, Thales Papagiannakopoulos, Colin T. Shearn, Elias S. J. Arnér, and Edward E. SchmidtPNAS June 4, 2019 116 (23) 11408-11417; first published May 16, 2019. https://doi.org/10.1073/pnas.1903244116
- Open AccessActivation of unliganded FGF receptor by extracellular phosphate potentiates proteolytic protection of FGF23 by its O-glycosylationYuichi Takashi, Hidetaka Kosako, Shun Sawatsubashi, Yuka Kinoshita, Nobuaki Ito, Maria K. Tsoumpra, Masaomi Nangaku, Masahiro Abe, Munehide Matsuhisa, Shigeaki Kato, Toshio Matsumoto, and Seiji FukumotoPNAS June 4, 2019 116 (23) 11418-11427; first published May 16, 2019. https://doi.org/10.1073/pnas.1815166116
- Open AccessGenomic correlates of clinical outcome in advanced prostate cancer
- From the Cover
Wassim Abida, Joanna Cyrta, Glenn Heller, Davide Prandi, Joshua Armenia, Ilsa Coleman, Marcin Cieslik, Matteo Benelli, Dan Robinson, Eliezer M. Van Allen, Andrea Sboner, Tarcisio Fedrizzi, Juan Miguel Mosquera, Brian D. Robinson, Navonil De Sarkar, Lakshmi P. Kunju, Scott Tomlins, Yi Mi Wu, Daniel Nava Rodrigues, Massimo Loda, Anuradha Gopalan, Victor E. Reuter, Colin C. Pritchard, Joaquin Mateo, Diletta Bianchini, Susana Miranda, Suzanne Carreira, Pasquale Rescigno, Julie Filipenko, Jacob Vinson, Robert B. Montgomery, Himisha Beltran, Elisabeth I. Heath, Howard I. Scher, Philip W. Kantoff, Mary-Ellen Taplin, Nikolaus Schultz, Johann S. deBono, Francesca Demichelis, Peter S. Nelson, Mark A. Rubin, Arul M. Chinnaiyan, and Charles L. SawyersPNAS June 4, 2019 116 (23) 11428-11436; first published May 6, 2019. https://doi.org/10.1073/pnas.1902651116See companion article:
- You have accessEstrogen receptor signaling is reprogrammed during breast tumorigenesisDavid Chi, Hari Singhal, Lewyn Li, Tengfei Xiao, Weihan Liu, Matthew Pun, Rinath Jeselsohn, Housheng He, Elgene Lim, Raga Vadhi, Prakash Rao, Henry Long, Judy Garber, and Myles BrownPNAS June 4, 2019 116 (23) 11437-11443; first published May 20, 2019. https://doi.org/10.1073/pnas.1819155116
- You have accessA human organoid system that self-organizes to recapitulate growth and differentiation of a benign mammary tumorStefan Florian, Yoshiko Iwamoto, Margaret Coughlin, Ralph Weissleder, and Timothy J. MitchisonPNAS June 4, 2019 116 (23) 11444-11453; first published May 17, 2019. https://doi.org/10.1073/pnas.1702372116
Microbiology
- Open AccessSystematic evasion of the restriction-modification barrier in bacteriaChristopher D. Johnston, Sean L. Cotton, Susan R. Rittling, Jacqueline R. Starr, Gary G. Borisy, Floyd E. Dewhirst, and Katherine P. LemonPNAS June 4, 2019 116 (23) 11454-11459; first published May 16, 2019. https://doi.org/10.1073/pnas.1820256116
- You have accessA glycan shield on chimpanzee CD4 protects against infection by primate lentiviruses (HIV/SIV)Cody J. Warren, Nicholas R. Meyerson, Alex C. Stabell, Will T. Fattor, Gregory K. Wilkerson, and Sara L. SawyerPNAS June 4, 2019 116 (23) 11460-11469; first published May 21, 2019. https://doi.org/10.1073/pnas.1813909116
- You have accessStructural and functional analyses of the N-terminal domain of the A subunit of a Bacillus megaterium spore germinant receptorYunfeng Li, Kai Jin, Abigail Perez-Valdespino, Kyle Federkiewicz, Andrew Davis, Mark W. Maciejewski, Peter Setlow, and Bing HaoPNAS June 4, 2019 116 (23) 11470-11479; first published May 21, 2019. https://doi.org/10.1073/pnas.1903675116
Neuroscience
- You have accessUltrafast optical clearing method for three-dimensional imaging with cellular resolutionXinpei Zhu, Limeng Huang, Yao Zheng, Yanchun Song, Qiaoqi Xu, Jiahao Wang, Ke Si, Shumin Duan, and Wei GongPNAS June 4, 2019 116 (23) 11480-11489; first published May 17, 2019. https://doi.org/10.1073/pnas.1819583116
- You have accessIn vivo evidence for dysregulation of mGluR5 as a biomarker of suicidal ideationMargaret T. Davis, Ansel Hillmer, Sophie E. Holmes, Robert H. Pietrzak, Nicole DellaGioia, Nabeel Nabulsi, David Matuskey, Gustavo A. Angarita, Richard E. Carson, John H. Krystal, and Irina EsterlisPNAS June 4, 2019 116 (23) 11490-11495; first published May 13, 2019. https://doi.org/10.1073/pnas.1818871116
Pharmacology
- You have accessInterrogating dense ligand chemical space with a forward-synthetic libraryFlorent Chevillard, Silvia Stotani, Anna Karawajczyk, Stanimira Hristeva, Els Pardon, Jan Steyaert, Dimitrios Tzalis, and Peter KolbPNAS June 4, 2019 116 (23) 11496-11501; first published May 21, 2019. https://doi.org/10.1073/pnas.1818718116
Physiology
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Plant Biology
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Psychological and Cognitive Sciences
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Correction
- You have accessCorrection for Kröger et al., Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cellsPNAS June 4, 2019 116 (23) 11553-11554; first published May 28, 2019. https://doi.org/10.1073/pnas.1907473116
Commentaries
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