Proceedings of the National Academy of Sciences: 116 (3)

New Research In

January 15, 2019; vol. 116 no. 3

This Week in PNAS

You have access
In This Issue
PNAS January 15, 2019 116 (3) 701-703; https://doi.org/10.1073/iti0319116

Editorial

You have access
Proceedings of the National Academy of Sciences—Its evolution and adaptation
May R. Berenbaum

PNAS January 15, 2019 116 (3) 704-706; first published January 7, 2019. https://doi.org/10.1073/pnas.1821201116

Science and Culture

How science intersects with culture.

You have access
Science and Culture: Searching for the science behind art therapy
Front Matter
Carolyn Beans

PNAS January 15, 2019 116 (3) 707-710; https://doi.org/10.1073/pnas.1821297116

Inner Workings

An over-the-shoulder look at scientists at work.

You have access
Inner Workings: How bacteria could help recycle electronic waste
Front Matter
Roberta Kwok

PNAS January 15, 2019 116 (3) 711-713; https://doi.org/10.1073/pnas.1820329116

Commentaries

You have access
Reduced emissions through climate damage to the economy
Ken Caldeira and Patrick T. Brown

PNAS January 15, 2019 116 (3) 714-716; first published December 27, 2018. https://doi.org/10.1073/pnas.1819605116
See companion article:
Economic carbon cycle feedbacks may offset additional warming from natural feedbacks
- Dec 17, 2018
You have access
Small patches make critical contributions to biodiversity conservation
David Lindenmayer

PNAS January 15, 2019 116 (3) 717-719; first published December 27, 2018. https://doi.org/10.1073/pnas.1820169116
See companion article:
Global synthesis of conservation studies reveals the importance of small habitat patches for biodiversity
- Dec 10, 2018
You have access
Creative citizen science illuminates complex ecological responses to climate change
Abraham J. Miller-Rushing, Amanda S. Gallinat, and Richard B. Primack

PNAS January 15, 2019 116 (3) 720-722; first published January 4, 2019. https://doi.org/10.1073/pnas.1820266116
See companion article:
Climate-induced phenological shifts in a Batesian mimicry complex
- Dec 03, 2018

Perspective

Open Access
Nutrition, the visceral immune system, and the evolutionary origins of pathogenic obesity
Mary Jane West-Eberhard

PNAS January 15, 2019 116 (3) 723-731; first published December 31, 2018. https://doi.org/10.1073/pnas.1809046116

Physical Sciences

Applied Mathematics
- You have access
  Linear variational principle for Riemann mappings and discrete conformality
  Nadav Dym, Raz Slutsky, and Yaron Lipman
  
  PNAS January 15, 2019 116 (3) 732-737; first published December 28, 2018. https://doi.org/10.1073/pnas.1809731116
Applied Physical Sciences
- You have access
  Interfacial fluid transport is a key to hydrogel bioadhesion
  Raphaël Michel, Léna Poirier, Quentin van Poelvoorde, Josette Legagneux, Mathieu Manassero, and Laurent Corté
  
  PNAS January 15, 2019 116 (3) 738-743; first published January 2, 2019. https://doi.org/10.1073/pnas.1813208116
Biophysics and Computational Biology
- Open Access
  Photoswitching FRET to monitor protein–protein interactions
  Kristin H. Rainey and George H. Patterson
  
  PNAS January 15, 2019 116 (3) 864-873; first published December 31, 2018. https://doi.org/10.1073/pnas.1805333116
- Open Access
  Rigidification of the Escherichia coli cytoplasm by the human antimicrobial peptide LL-37 revealed by superresolution fluorescence microscopy
  Yanyu Zhu, Sonisilpa Mohapatra, and James C. Weisshaar
  
  PNAS January 15, 2019 116 (3) 1017-1026; first published December 31, 2018. https://doi.org/10.1073/pnas.1814924116
- You have access
  Ca²⁺-activated Cl⁻ current ensures robust and reliable signal amplification in vertebrate olfactory receptor neurons
  Johannes Reisert and Jürgen Reingruber
  
  PNAS January 15, 2019 116 (3) 1053-1058; first published December 31, 2018. https://doi.org/10.1073/pnas.1816371116
Chemistry
- Open Access
  Bioactive cell-like hybrids from dendrimersomes with a human cell membrane and its components
  Srujana S. Yadavalli, Qi Xiao, Samuel E. Sherman, William D. Hasley, Michael L. Klein, Mark Goulian, and Virgil Percec
  
  PNAS January 15, 2019 116 (3) 744-752; first published December 27, 2018. https://doi.org/10.1073/pnas.1811307116
- Open Access
  Mcm10 has potent strand-annealing activity and limits translocase-mediated fork regression
  Ryan Mayle, Lance Langston, Kelly R. Molloy, Dan Zhang, Brian T. Chait, and Michael E. O’Donnell
  
  PNAS January 15, 2019 116 (3) 798-803; first published December 31, 2018. https://doi.org/10.1073/pnas.1819107116
Earth, Atmospheric, and Planetary Sciences
- You have access
  Nanoscale infrared imaging analysis of carbonaceous chondrites to understand organic-mineral interactions during aqueous alteration
  Yoko Kebukawa, Hanae Kobayashi, Norio Urayama, Naoki Baden, Masashi Kondo, Michael E. Zolensky, and Kensei Kobayashi
  
  PNAS January 15, 2019 116 (3) 753-758; first published January 2, 2019. https://doi.org/10.1073/pnas.1816265116
Environmental Sciences
- Open Access
  Economic carbon cycle feedbacks may offset additional warming from natural feedbacks
  From the Cover
  
  Dawn L. Woodard, Steven J. Davis, and James T. Randerson
  
  PNAS January 15, 2019 116 (3) 759-764; first published December 17, 2018. https://doi.org/10.1073/pnas.1805187115
  
  See companion article:
  Reduced emissions through climate damage to the economy
  - Dec 27, 2018
Physics
- You have access
  Direct electrochemical generation of supercooled sulfur microdroplets well below their melting temperature
  Nian Liu, Guangmin Zhou, Ankun Yang, Xiaoyun Yu, Feifei Shi, Jie Sun, Jinsong Zhang, Bofei Liu, Chun-Lan Wu, Xinyong Tao, Yongming Sun, Yi Cui, and Steven Chu
  
  PNAS January 15, 2019 116 (3) 765-770; first published January 2, 2019. https://doi.org/10.1073/pnas.1817286116
- Open Access
  Thermal disequilibration of ions and electrons by collisionless plasma turbulence
  Yohei Kawazura, Michael Barnes, and Alexander A. Schekochihin
  
  PNAS January 15, 2019 116 (3) 771-776; first published December 31, 2018. https://doi.org/10.1073/pnas.1812491116
- You have access
  Data-driven quantitative modeling of bacterial active nematics
  He Li, Xia-qing Shi, Mingji Huang, Xiao Chen, Minfeng Xiao, Chenli Liu, Hugues Chaté, and H. P. Zhang
  
  PNAS January 15, 2019 116 (3) 777-785; first published December 28, 2018. https://doi.org/10.1073/pnas.1812570116

Biological Sciences

Biochemistry
- Open Access
  Bioactive cell-like hybrids from dendrimersomes with a human cell membrane and its components
  Srujana S. Yadavalli, Qi Xiao, Samuel E. Sherman, William D. Hasley, Michael L. Klein, Mark Goulian, and Virgil Percec
  
  PNAS January 15, 2019 116 (3) 744-752; first published December 27, 2018. https://doi.org/10.1073/pnas.1811307116
- Open Access
  Mcm10 has potent strand-annealing activity and limits translocase-mediated fork regression
  Ryan Mayle, Lance Langston, Kelly R. Molloy, Dan Zhang, Brian T. Chait, and Michael E. O’Donnell
  
  PNAS January 15, 2019 116 (3) 798-803; first published December 31, 2018. https://doi.org/10.1073/pnas.1819107116
- Open Access
  Structural basis for prodrug recognition by the SLC15 family of proton-coupled peptide transporters
  Gurdeep S. Minhas and Simon Newstead
  
  PNAS January 15, 2019 116 (3) 804-809; first published January 2, 2019. https://doi.org/10.1073/pnas.1813715116
- You have access
  Arrestin-3 scaffolding of the JNK3 cascade suggests a mechanism for signal amplification
  Nicole A. Perry, Tamer S. Kaoud, Oscar O. Ortega, Ali I. Kaya, David J. Marcus, John M. Pleinis, Sandra Berndt, Qiuyan Chen, Xuanzhi Zhan, Kevin N. Dalby, Carlos F. Lopez, T. M. Iverson, and Vsevolod V. Gurevich
  
  PNAS January 15, 2019 116 (3) 810-815; first published December 27, 2018. https://doi.org/10.1073/pnas.1819230116
- You have access
  DNA damage and genome instability by G-quadruplex ligands are mediated by R loops in human cancer cells
  Alessio De Magis, Stefano G. Manzo, Marco Russo, Jessica Marinello, Rita Morigi, Olivier Sordet, and Giovanni Capranico
  
  PNAS January 15, 2019 116 (3) 816-825; first published December 27, 2018. https://doi.org/10.1073/pnas.1810409116
- You have access
  ParST is a widespread toxin–antitoxin module that targets nucleotide metabolism
  Frank J. Piscotta, Philip D. Jeffrey, and A. James Link
  
  PNAS January 15, 2019 116 (3) 826-834; first published December 31, 2018. https://doi.org/10.1073/pnas.1814633116
- You have access
  Biosynthesis of mycobacterial methylmannose polysaccharides requires a unique 1-O-methyltransferase specific for 3-O-methylated mannosides
  Jorge Ripoll-Rozada, Mafalda Costa, José A. Manso, Ana Maranha, Vanessa Miranda, André Sequeira, M. Rita Ventura, Sandra Macedo-Ribeiro, Pedro José Barbosa Pereira, and Nuno Empadinhas
  
  PNAS January 15, 2019 116 (3) 835-844; first published January 3, 2019. https://doi.org/10.1073/pnas.1813450116
Biophysics and Computational Biology
- You have access
  Two symmetric arginine residues play distinct roles in Thermus thermophilus Argonaute DNA guide strand-mediated DNA target cleavage
  Jinping Lei, Gang Sheng, Peter Pak-Hang Cheung, Shenglong Wang, Yu Li, Xin Gao, Yingkai Zhang, Yanli Wang, and Xuhui Huang
  
  PNAS January 15, 2019 116 (3) 845-853; first published December 27, 2018. https://doi.org/10.1073/pnas.1817041116
- You have access
  Role of domain interactions in the aggregation of full-length immunoglobulin light chains
  Enrico Rennella, Gareth J. Morgan, Jeffery W. Kelly, and Lewis E. Kay
  
  PNAS January 15, 2019 116 (3) 854-863; first published December 31, 2018. https://doi.org/10.1073/pnas.1817538116
Cell Biology
- Open Access
  Photoswitching FRET to monitor protein–protein interactions
  Kristin H. Rainey and George H. Patterson
  
  PNAS January 15, 2019 116 (3) 864-873; first published December 31, 2018. https://doi.org/10.1073/pnas.1805333116
- You have access
  Patched1–ArhGAP36–PKA–Inversin axis determines the ciliary translocation of Smoothened for Sonic Hedgehog pathway activation
  Boyan Zhang, Tenghan Zhuang, Qiaoyu Lin, Biying Yang, Xiaowei Xu, Guangwei Xin, Shicong Zhu, Gang Wang, Bin Yu, Tingting Zhang, Qing Jiang, and Chuanmao Zhang
  
  PNAS January 15, 2019 116 (3) 874-879; first published December 31, 2018. https://doi.org/10.1073/pnas.1804042116
- Open Access
  Single-molecule imaging of the transcription factor SRF reveals prolonged chromatin-binding kinetics upon cell stimulation
  Lisa Hipp, Judith Beer, Oliver Kuchler, Matthias Reisser, Daniela Sinske, Jens Michaelis, J. Christof M. Gebhardt, and Bernd Knöll
  
  PNAS January 15, 2019 116 (3) 880-889; first published December 31, 2018. https://doi.org/10.1073/pnas.1812734116
- You have access
  Different roles of E proteins in t(8;21) leukemia: E2-2 compromises the function of AETFC and negatively regulates leukemogenesis
  Na Liu, Junhong Song, Yangyang Xie, Xiao-Lin Wang, Bowen Rong, Na Man, Meng-Meng Zhang, Qunling Zhang, Fei-Fei Gao, Mei-Rong Du, Ying Zhang, Jian Shen, Chun-Hui Xu, Cheng-Long Hu, Ji-Chuan Wu, Ping Liu, Yuan-Liang Zhang, Yin-Yin Xie, Ping Liu, Jin-Yan Huang, Qiu-Hua Huang, Fei Lan, Shuhong Shen, Stephen D. Nimer, Zhu Chen, Sai-Juan Chen, Robert G. Roeder, Lan Wang, and Xiao-Jian Sun
  
  PNAS January 15, 2019 116 (3) 890-899; first published December 28, 2018. https://doi.org/10.1073/pnas.1809327116
Developmental Biology
- Open Access
  Exploiting regulatory heterogeneity to systematically identify enhancers with high accuracy
  Hamutal Arbel, Sumanta Basu, William W. Fisher, Ann S. Hammonds, Kenneth H. Wan, Soo Park, Richard Weiszmann, Benjamin W. Booth, Soile V. Keranen, Clara Henriquez, Omid Shams Solari, Peter J. Bickel, Mark D. Biggin, Susan E. Celniker, and James B. Brown
  
  PNAS January 15, 2019 116 (3) 900-908; first published December 31, 2018. https://doi.org/10.1073/pnas.1808833115
Ecology
- Open Access
  Global synthesis of conservation studies reveals the importance of small habitat patches for biodiversity
  From the Cover
  
  Brendan A. Wintle, Heini Kujala, Amy Whitehead, Alison Cameron, Sam Veloz, Aija Kukkala, Atte Moilanen, Ascelin Gordon, Pia E. Lentini, Natasha C. R. Cadenhead, and Sarah A. Bekessy
  
  PNAS January 15, 2019 116 (3) 909-914; first published December 10, 2018. https://doi.org/10.1073/pnas.1813051115
  
  See companion article:
  Small patches make critical contributions to biodiversity conservation
  - Dec 27, 2018
- Open Access
  Global-scale dispersal and connectivity in mangroves
  From the Cover
  
  Tom Van der Stocken, Dustin Carroll, Dimitris Menemenlis, Marc Simard, and Nico Koedam
  
  PNAS January 15, 2019 116 (3) 915-922; first published December 31, 2018. https://doi.org/10.1073/pnas.1812470116
Evolution
- Open Access
  The genomic basis of Red Queen dynamics during rapid reciprocal host–pathogen coevolution
  Andrei Papkou, Thiago Guzella, Wentao Yang, Svenja Koepper, Barbara Pees, Rebecca Schalkowski, Mike-Christoph Barg, Philip C. Rosenstiel, Henrique Teotónio, and Hinrich Schulenburg
  
  PNAS January 15, 2019 116 (3) 923-928; first published December 31, 2018. https://doi.org/10.1073/pnas.1810402116
- You have access
  Climate-induced phenological shifts in a Batesian mimicry complex
  From the Cover
  
  Christopher Hassall, Jac Billington, and Thomas N. Sherratt
  
  PNAS January 15, 2019 116 (3) 929-933; first published December 3, 2018. https://doi.org/10.1073/pnas.1813367115
  
  See companion article:
  Creative citizen science illuminates complex ecological responses to climate change
  - Jan 04, 2019
- You have access
  Novel genetic code and record-setting AT-richness in the highly reduced plastid genome of the holoparasitic plant Balanophora
  Huei-Jiun Su, Todd J. Barkman, Weilong Hao, Samuel S. Jones, Julia Naumann, Elizabeth Skippington, Eric K. Wafula, Jer-Ming Hu, Jeffrey D. Palmer, and Claude W. dePamphilis
  
  PNAS January 15, 2019 116 (3) 934-943; first published December 31, 2018. https://doi.org/10.1073/pnas.1816822116
Genetics
- You have access
  HIV peptidome-wide association study reveals patient-specific epitope repertoires associated with HIV control
  Jatin Arora, Paul J. McLaren, Nimisha Chaturvedi, Mary Carrington, Jacques Fellay, and Tobias L. Lenz
  
  PNAS January 15, 2019 116 (3) 944-949; first published January 2, 2019. https://doi.org/10.1073/pnas.1812548116
- You have access
  Blacklisting variants common in private cohorts but not in public databases optimizes human exome analysis
  Patrick Maffucci, Benedetta Bigio, Franck Rapaport, Aurélie Cobat, Alessandro Borghesi, Marie Lopez, Etienne Patin, Alexandre Bolze, Lei Shang, Matthieu Bendavid, Eric M. Scott, Peter D. Stenson, Charlotte Cunningham-Rundles, David N. Cooper, Joseph G. Gleeson, Jacques Fellay, Lluis Quintana-Murci, Jean-Laurent Casanova, Laurent Abel, Bertrand Boisson, and Yuval Itan
  
  PNAS January 15, 2019 116 (3) 950-959; first published December 27, 2018. https://doi.org/10.1073/pnas.1808403116
- You have access
  Constitutive Dicer1 phosphorylation accelerates metabolism and aging in vivo
  Neeraj K. Aryal, Vinod Pant, Amanda R. Wasylishen, Jan Parker-Thornburg, Laura Baseler, Adel K. El-Naggar, Bin Liu, Awdhesh Kalia, Guillermina Lozano, and Swathi Arur
  
  PNAS January 15, 2019 116 (3) 960-969; first published December 28, 2018. https://doi.org/10.1073/pnas.1814377116
Immunology and Inflammation
- You have access
  Human RIPK1 deficiency causes combined immunodeficiency and inflammatory bowel diseases
  Yue Li, Marita Führer, Ehsan Bahrami, Piotr Socha, Maja Klaudel-Dreszler, Amira Bouzidi, Yanshan Liu, Anna S. Lehle, Thomas Magg, Sebastian Hollizeck, Meino Rohlfs, Raffaele Conca, Michael Field, Neil Warner, Slae Mordechai, Eyal Shteyer, Dan Turner, Rachida Boukari, Reda Belbouab, Christoph Walz, Moritz M. Gaidt, Veit Hornung, Bernd Baumann, Ulrich Pannicke, Eman Al Idrissi, Hamza Ali Alghamdi, Fernando E. Sepulveda, Marine Gil, Geneviève de Saint Basile, Manfred Hönig, Sibylle Koletzko, Aleixo M. Muise, Scott B. Snapper, Klaus Schwarz, Christoph Klein, and Daniel Kotlarz
  
  PNAS January 15, 2019 116 (3) 970-975; first published December 27, 2018. https://doi.org/10.1073/pnas.1813582116
- You have access
  RNA-binding protein YTHDF3 suppresses interferon-dependent antiviral responses by promoting FOXO3 translation
  Yuan Zhang, Xin Wang, Xiao Zhang, Jiaming Wang, Yuanwu Ma, Lianfeng Zhang, and Xuetao Cao
  
  PNAS January 15, 2019 116 (3) 976-981; first published December 27, 2018. https://doi.org/10.1073/pnas.1812536116
- You have access
  Phosphatase PP2A is essential for T_H17 differentiation
  Qin Xu, Xuexiao Jin, Mingzhu Zheng, Deepak Rohila, Guotong Fu, Zhuoyu Wen, Jun Lou, Songquan Wu, Richard Sloan, Lie Wang, Hu Hu, Xiang Gao, and Linrong Lu
  
  PNAS January 15, 2019 116 (3) 982-987; first published December 28, 2018. https://doi.org/10.1073/pnas.1807484116
- You have access
  Binding mode of the side-by-side two-IgV molecule CD226/DNAM-1 to its ligand CD155/Necl-5
  Han Wang, Jianxun Qi, Shuijun Zhang, Yan Li, Shuguang Tan, and George F. Gao
  
  PNAS January 15, 2019 116 (3) 988-996; first published December 27, 2018. https://doi.org/10.1073/pnas.1815716116
- Open Access
  Microglia are effector cells of CD47-SIRPα antiphagocytic axis disruption against glioblastoma
  Gregor Hutter, Johanna Theruvath, Claus Moritz Graef, Michael Zhang, Matthew Kenneth Schoen, Eva Maria Manz, Mariko L. Bennett, Andrew Olson, Tej D. Azad, Rahul Sinha, Carmel Chan, Suzana Assad Kahn, Sharareh Gholamin, Christy Wilson, Gerald Grant, Joy He, Irving L. Weissman, Siddhartha S. Mitra, and Samuel H. Cheshier
  
  PNAS January 15, 2019 116 (3) 997-1006; first published January 2, 2019. https://doi.org/10.1073/pnas.1721434116
- You have access
  Unregulated antigen-presenting cell activation by T cells breaks self tolerance
  Jaeu Yi, Jisun Jung, Sung-Wook Hong, Jun Young Lee, Daehee Han, Kwang Soon Kim, Jonathan Sprent, and Charles D. Surh
  
  PNAS January 15, 2019 116 (3) 1007-1016; first published December 31, 2018. https://doi.org/10.1073/pnas.1818624116
Medical Sciences
- You have access
  Interfacial fluid transport is a key to hydrogel bioadhesion
  Raphaël Michel, Léna Poirier, Quentin van Poelvoorde, Josette Legagneux, Mathieu Manassero, and Laurent Corté
  
  PNAS January 15, 2019 116 (3) 738-743; first published January 2, 2019. https://doi.org/10.1073/pnas.1813208116
Microbiology
- Open Access
  Rigidification of the Escherichia coli cytoplasm by the human antimicrobial peptide LL-37 revealed by superresolution fluorescence microscopy
  Yanyu Zhu, Sonisilpa Mohapatra, and James C. Weisshaar
  
  PNAS January 15, 2019 116 (3) 1017-1026; first published December 31, 2018. https://doi.org/10.1073/pnas.1814924116
- You have access
  Dual inhibition of MDM2 and MDM4 in virus-positive Merkel cell carcinoma enhances the p53 response
  Donglim Esther Park, Jingwei Cheng, Christian Berrios, Joan Montero, Marta Cortés-Cros, Stéphane Ferretti, Reety Arora, Michelle L. Tillgren, Prafulla C. Gokhale, and James A. DeCaprio
  
  PNAS January 15, 2019 116 (3) 1027-1032; first published December 31, 2018. https://doi.org/10.1073/pnas.1818798116
- You have access
  Herpes simplex virus 1 ICP8 mutant lacking annealing activity is deficient for viral DNA replication
  Savithri Weerasooriya, Katherine A. DiScipio, Anthar S. Darwish, Ping Bai, and Sandra K. Weller
  
  PNAS January 15, 2019 116 (3) 1033-1042; first published December 31, 2018. https://doi.org/10.1073/pnas.1817642116
- You have access
  Regulation of acetate metabolism and coordination with the TCA cycle via a processed small RNA
  François De Mets, Laurence Van Melderen, and Susan Gottesman
  
  PNAS January 15, 2019 116 (3) 1043-1052; first published December 27, 2018. https://doi.org/10.1073/pnas.1815288116
Neuroscience
- You have access
  Ca²⁺-activated Cl⁻ current ensures robust and reliable signal amplification in vertebrate olfactory receptor neurons
  Johannes Reisert and Jürgen Reingruber
  
  PNAS January 15, 2019 116 (3) 1053-1058; first published December 31, 2018. https://doi.org/10.1073/pnas.1816371116
- You have access
  Conotoxin κM-RIIIJ, a tool targeting asymmetric heteromeric K_v1 channels
  Sönke Cordeiro, Rocio K. Finol-Urdaneta, David Köpfer, Anna Markushina, Jie Song, Robert J. French, Wojciech Kopec, Bert L. de Groot, Mario J. Giacobassi, Lee S. Leavitt, Shrinivasan Raghuraman, Russell W. Teichert, Baldomero M. Olivera, and Heinrich Terlau
  
  PNAS January 15, 2019 116 (3) 1059-1064; first published December 28, 2018. https://doi.org/10.1073/pnas.1813161116

Corrections

You have access
Correction for Li et al., Pressure-induced phase transitions and superconductivity in a black phosphorus single crystal
PNAS January 15, 2019 116 (3) 1065; first published January 7, 2019. https://doi.org/10.1073/pnas.1821331116
You have access
Correction for Paluck et al., Changing climates of conflict: A social network experiment in 56 schools
PNAS January 15, 2019 116 (3) 1066; first published January 7, 2019. https://doi.org/10.1073/pnas.1821346116
You have access
Correction for Terui et al., Metapopulation stability in branching river networks
PNAS January 15, 2019 116 (3) 1067-1068; first published January 7, 2019. https://doi.org/10.1073/pnas.1821107116
You have access
Correction for Zella et al., Mycoplasma promotes malignant transformation in vivo, and its DnaK, a bacterial chaperon protein, has broad oncogenic properties
PNAS January 15, 2019 116 (3) 1069; first published January 7, 2019. https://doi.org/10.1073/pnas.1821037116

Main menu

User menu

Search

New Research In

Physical Sciences

Featured Portals

Articles by Topic

Social Sciences

Featured Portals

Articles by Topic

Biological Sciences

Featured Portals

Articles by Topic

Table of Contents

This Week in PNAS

Editorial

Science and Culture

Inner Workings

Commentaries

See companion article:

See companion article:

See companion article:

Perspective

Physical Sciences

Applied Mathematics

Applied Physical Sciences

Biophysics and Computational Biology

Chemistry

Earth, Atmospheric, and Planetary Sciences

Environmental Sciences

See companion article:

Physics

Social Sciences

Economic Sciences

Social Sciences

Biological Sciences

Biochemistry

Biophysics and Computational Biology

Cell Biology

Developmental Biology

Ecology

See companion article:

Evolution

See companion article:

Genetics

Immunology and Inflammation

Medical Sciences

Microbiology

Neuroscience

Corrections

In this issue

Jump to

Articles

PNAS Portals

Information