Table of Contents

Biological Sciences

• Anthropology

  • Open Access

    Ancient pigs reveal a near-complete genomic turnover following their introduction to Europe

    Laurent A. F. Frantz, James Haile, Audrey T. Lin, Amelie Scheu, Christina Geörg, Norbert Benecke, Michelle Alexander, Anna Linderholm, Victoria E. Mullin, Kevin G. Daly, Vincent M. Battista, Max Price, Kurt J. Gron, Panoraia Alexandri, Rose-Marie Arbogast, Benjamin Arbuckle, Adrian Bӑlӑşescu, Ross Barnett, László Bartosiewicz, Gennady Baryshnikov, Clive Bonsall, Dušan Borić, Adina Boroneanţ, Jelena Bulatović, Canan Çakirlar, José-Miguel Carretero, John Chapman, Mike Church, Richard Crooijmans, Bea De Cupere, Cleia Detry, Vesna Dimitrijevic, Valentin Dumitraşcu, Louis du Plessis, Ceiridwen J. Edwards, Cevdet Merih Erek, Aslı Erim-Özdoğan, Anton Ervynck, Domenico Fulgione, Mihai Gligor, Anders Götherström, Lionel Gourichon, Martien A.M. Groenen, Daniel Helmer, Hitomi Hongo, Liora K. Horwitz, Evan K. Irving-Pease, Ophélie Lebrasseur, Joséphine Lesur, Caroline Malone, Ninna Manaseryan, Arkadiusz Marciniak, Holley Martlew, Marjan Mashkour, Roger Matthews, Giedre Motuzaite Matuzeviciute, Sepideh Maziar, Erik Meijaard, Tom McGovern, Hendrik-Jan Megens, Rebecca Miller, Azadeh Fatemeh Mohaseb, Jörg Orschiedt, David Orton, Anastasia Papathanasiou, Mike Parker Pearson, Ron Pinhasi, Darko Radmanović, François-Xavier Ricaut, Mike Richards, Richard Sabin, Lucia Sarti, Wolfram Schier, Shiva Sheikhi, Elisabeth Stephan, John R. Stewart, Simon Stoddart, Antonio Tagliacozzo, Nenad Tasić, Katerina Trantalidou, Anne Tresset, Cristina Valdiosera, Youri van den Hurk, Sophie Van Poucke, Jean-Denis Vigne, Alexander Yanevich, Andrea Zeeb-Lanz, Alexandros Triantafyllidis, M. Thomas P. Gilbert, Jörg Schibler, Peter Rowley-Conwy, Melinda Zeder, Joris Peters, Thomas Cucchi, Daniel G. Bradley, Keith Dobney, Joachim Burger, Allowen Evin, Linus Girdland-Flink, and Greger Larson

    PNAS August 27, 2019 116 (35) 17231-17238; first published August 12, 2019. https://doi.org/10.1073/pnas.1901169116

• Biochemistry

  • Open Access

    Hydrophobic catalysis and a potential biological role of DNA unstacking induced by environment effects

    Bobo Feng, Robert P. Sosa, Anna K. F. Mårtensson, Kai Jiang, Alex Tong, Kevin D. Dorfman, Masayuki Takahashi, Per Lincoln, Carlos J. Bustamante, Fredrik Westerlund, and Bengt Nordén

    PNAS August 27, 2019 116 (35) 17169-17174; first published August 14, 2019. https://doi.org/10.1073/pnas.1909122116
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    Prebiotic amino acids bind to and stabilize prebiotic fatty acid membranes

    Caitlin E. Cornell, Roy A. Black, Mengjun Xue, Helen E. Litz, Andrew Ramsay, Moshe Gordon, Alexander Mileant, Zachary R. Cohen, James A. Williams, Kelly K. Lee, Gary P. Drobny, and Sarah L. Keller

    PNAS August 27, 2019 116 (35) 17239-17244; first published August 12, 2019. https://doi.org/10.1073/pnas.1900275116
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    Characterization of glutamyl-tRNA–dependent dehydratases using nonreactive substrate mimics

    Ian R. Bothwell, Dillon P. Cogan, Terry Kim, Christopher J. Reinhardt, Wilfred A. van der Donk, and Satish K. Nair

    PNAS August 27, 2019 116 (35) 17245-17250; first published August 13, 2019. https://doi.org/10.1073/pnas.1905240116
  • Open Access

    The crystal structure of human microsomal triglyceride transfer protein

    Ekaterina I. Biterova, Michail N. Isupov, Ronan M. Keegan, Andrey A. Lebedev, Anil A. Sohail, Inam Liaqat, Heli I. Alanen, and Lloyd W. Ruddock

    PNAS August 27, 2019 116 (35) 17251-17260; first published August 8, 2019. https://doi.org/10.1073/pnas.1903029116
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    HuR counteracts miR-330 to promote STAT3 translation during inflammation-induced muscle wasting

    Souad Mubaid, Jennifer F. Ma, Amr Omer, Kholoud Ashour, Xian J. Lian, Brenda J. Sanchez, Samantha Robinson, Anne Cammas, Virginie Dormoy-Raclet, Sergio Di Marco, Sridar V. Chittur, Scott A. Tenenbaum, and Imed-Eddine Gallouzi

    PNAS August 27, 2019 116 (35) 17261-17270; first published August 12, 2019. https://doi.org/10.1073/pnas.1905172116
  • Open Access

    A pathway linking translation stress to checkpoint kinase 2 signaling in Neurospora crassa

    Axel C. R. Diernfellner, Linda Lauinger, Anton Shostak, and Michael Brunner

    PNAS August 27, 2019 116 (35) 17271-17279; first published August 14, 2019. https://doi.org/10.1073/pnas.1815396116
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    Protein engineering of a ubiquitin-variant inhibitor of APC/C identifies a cryptic K48 ubiquitin chain binding site

    • From the Cover

    Edmond R. Watson, Christy R. R. Grace, Wei Zhang, Darcie J. Miller, Iain F. Davidson, J. Rajan Prabu, Shanshan Yu, Derek L. Bolhuis, Elizaveta T. Kulko, Ronnald Vollrath, David Haselbach, Holger Stark, Jan-Michael Peters, Nicholas G. Brown, Sachdev S. Sidhu, and Brenda A. Schulman

    PNAS August 27, 2019 116 (35) 17280-17289; first published July 26, 2019. https://doi.org/10.1073/pnas.1902889116

    See companion article:

    • Ubiquitin in disguise unveils a cryptic binding site in 1.2-MDa anaphase-promoting complex/cyclosome

      - Aug 01, 2019
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    Second harmonic generation detection of Ras conformational changes and discovery of a small molecule binder

    Elizabeth Donohue, Sina Khorsand, Gabriel Mercado, Kristen M. Varney, Paul T. Wilder, Wenbo Yu, Alexander D. MacKerell Jr., Patrick Alexander, Que N. Van, Ben Moree, Andrew G. Stephen, David J. Weber, Joshua Salafsky, and Frank McCormick

    PNAS August 27, 2019 116 (35) 17290-17297; first published August 9, 2019. https://doi.org/10.1073/pnas.1905516116

• Biophysics and Computational Biology

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    High stretchability, strength, and toughness of living cells enabled by hyperelastic vimentin intermediate filaments

    Jiliang Hu, Yiwei Li, Yukun Hao, Tianqi Zheng, Satish K. Gupta, German Alberto Parada, Huayin Wu, Shaoting Lin, Shida Wang, Xuanhe Zhao, Robert D. Goldman, Shengqiang Cai, and Ming Guo

    PNAS August 27, 2019 116 (35) 17175-17180; first published August 13, 2019. https://doi.org/10.1073/pnas.1903890116
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    Motility-limited aggregation of mammary epithelial cells into fractal-like clusters

    Susan E. Leggett, Zachary J. Neronha, Dhananjay Bhaskar, Jea Yun Sim, Theodora Myrto Perdikari, and Ian Y. Wong

    PNAS August 27, 2019 116 (35) 17298-17306; first published August 14, 2019. https://doi.org/10.1073/pnas.1905958116
  • Open Access

    Nucleosome positions alone can be used to predict domains in yeast chromosomes

    Oliver Wiese, Davide Marenduzzo, and Chris A. Brackley

    PNAS August 27, 2019 116 (35) 17307-17315; first published August 15, 2019. https://doi.org/10.1073/pnas.1817829116
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    Structural and functional analyses of photosystem II in the marine diatom Phaeodactylum tricornutum

    Orly Levitan, Muyuan Chen, Xuyuan Kuang, Kuan Yu Cheong, Jennifer Jiang, Melissa Banal, Nikhita Nambiar, Maxim Y. Gorbunov, Steven J. Ludtke, Paul G. Falkowski, and Wei Dai

    PNAS August 27, 2019 116 (35) 17316-17322; first published August 13, 2019. https://doi.org/10.1073/pnas.1906726116
  • Open Access

    Generalized size scaling of metabolic rates based on single-cell measurements with freshwater phytoplankton

    Silvia Zaoli, Andrea Giometto, Emilio Marañón, Stéphane Escrig, Anders Meibom, Arti Ahluwalia, Roman Stocker, Amos Maritan, and Andrea Rinaldo

    PNAS August 27, 2019 116 (35) 17323-17329; first published August 13, 2019. https://doi.org/10.1073/pnas.1906762116
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    Controlling the material properties and rRNA processing function of the nucleolus using light

    Lian Zhu, Tiffany M. Richardson, Ludivine Wacheul, Ming-Tzo Wei, Marina Feric, Gena Whitney, Denis L. J. Lafontaine, and Clifford P. Brangwynne

    PNAS August 27, 2019 116 (35) 17330-17335; first published August 9, 2019. https://doi.org/10.1073/pnas.1903870116
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    Spreading of perturbations in myosin group kinetics along actin filaments

    Zsombor Balassy, Anne-Marie Lauzon, and Lennart Hilbert

    PNAS August 27, 2019 116 (35) 17336-17344; first published August 12, 2019. https://doi.org/10.1073/pnas.1904164116
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    Mutation of external glutamate residue reveals a new intermediate transport state and anion binding site in a CLC Cl⁻/H⁺ antiporter

    Kunwoong Park, Byoung-Cheol Lee, and Hyun-Ho Lim

    PNAS August 27, 2019 116 (35) 17345-17354; first published August 13, 2019. https://doi.org/10.1073/pnas.1901822116

• Cell Biology

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    Autophosphorylation is sufficient to release Mps1 kinase from native kinetochores

    Lori B. Koch, Kwaku N. Opoku, Yi Deng, Adrienne Barber, Aimee J. Littleton, Nitobe London, Sue Biggins, and Charles L. Asbury

    PNAS August 27, 2019 116 (35) 17355-17360; first published August 12, 2019. https://doi.org/10.1073/pnas.1901653116
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    Single-cell RNA-seq identifies a reversible mesodermal activation in abnormally specified epithelia of p63 EEC syndrome

    Eduardo Soares, Quan Xu, Qingqing Li, Jieqiong Qu, Yuxuan Zheng, Henriette H. M. Raeven, Karina O. Brandao, Isabelle Petit, Willem M. R. van den Akker, Simon J. van Heeringen, Daniel Aberdam, Fuchou Tang, and Huiqing Zhou

    PNAS August 27, 2019 116 (35) 17361-17370; first published August 14, 2019. https://doi.org/10.1073/pnas.1908180116

• Ecology

  • Open Access

    Mesoscale eddies release pelagic sharks from thermal constraints to foraging in the ocean twilight zone

    • From the Cover

    Camrin D. Braun, Peter Gaube, Tane H. Sinclair-Taylor, Gregory B. Skomal, and Simon R. Thorrold

    PNAS August 27, 2019 116 (35) 17187-17192; first published August 6, 2019. https://doi.org/10.1073/pnas.1903067116
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    Biomass losses resulting from insect and disease invasions in US forests

    • From the Cover

    Songlin Fei, Randall S. Morin, Christopher M. Oswalt, and Andrew M. Liebhold

    PNAS August 27, 2019 116 (35) 17371-17376; first published August 12, 2019. https://doi.org/10.1073/pnas.1820601116

• Genetics

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    Essential Saccharomyces cerevisiae genome instability suppressing genes identify potential human tumor suppressors

    Anjana Srivatsan, Binzhong Li, Dafne N. Sanchez, Steven B. Somach, Vandeclecio L. da Silva, Sandro J. de Souza, Christopher D. Putnam, and Richard D. Kolodner

    PNAS August 27, 2019 116 (35) 17377-17382; first published August 13, 2019. https://doi.org/10.1073/pnas.1906921116
  • Open Access

    Dietary restriction improves proteostasis and increases life span through endoplasmic reticulum hormesis

    Latika Matai, Gautam Chandra Sarkar, Manish Chamoli, Yasir Malik, Shashi Shekhar Kumar, Umanshi Rautela, Nihar Ranjan Jana, Kausik Chakraborty, and Arnab Mukhopadhyay

    PNAS August 27, 2019 116 (35) 17383-17392; first published August 14, 2019. https://doi.org/10.1073/pnas.1900055116

• Immunology and Inflammation

  • Open Access

    A dynamical motif comprising the interactions between antigens and CD8 T cells may underlie the outcomes of viral infections

    Subhasish Baral, Rustom Antia, and Narendra M. Dixit

    PNAS August 27, 2019 116 (35) 17393-17398; first published August 14, 2019. https://doi.org/10.1073/pnas.1902178116
  • Open Access

    An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity

    Nora Schmidt, Patricia Domingues, Filip Golebiowski, Corinna Patzina, Michael H. Tatham, Ronald T. Hay, and Benjamin G. Hale

    PNAS August 27, 2019 116 (35) 17399-17408; first published August 7, 2019. https://doi.org/10.1073/pnas.1907031116
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    IL-17 constrains natural killer cell activity by restraining IL-15–driven cell maturation via SOCS3

    Xuefu Wang, Rui Sun, Xiaolei Hao, Zhe-Xiong Lian, Haiming Wei, and Zhigang Tian

    PNAS August 27, 2019 116 (35) 17409-17418; first published August 12, 2019. https://doi.org/10.1073/pnas.1904125116
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    Intrinsic expression of viperin regulates thermogenesis in adipose tissues

    • From the Cover

    John Eom, Jeong Jin Kim, Seul Gi Yoon, Haengdueng Jeong, Soojin Son, Jae Bong Lee, Jihye Yoo, Hyun Ju Seo, Yejin Cho, Ku Sul Kim, Kyung Mi Choi, Il Yong Kim, Hui-Young Lee, Ki Taek Nam, Peter Cresswell, Je Kyung Seong, and Jun-Young Seo

    PNAS August 27, 2019 116 (35) 17419-17428; first published July 24, 2019. https://doi.org/10.1073/pnas.1904480116

    See companion article:

    • Unknown actor in adipose tissue metabolism hiding in plain sight

      - Aug 07, 2019

• Medical Sciences

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    Transient enhancement of p53 activity protects from radiation-induced gastrointestinal toxicity

    Vinod Pant, Shunbin Xiong, Amanda R. Wasylishen, Connie A. Larsson, Neeraj K. Aryal, Gilda Chau, Ramesh C. Tailor, and Guillermina Lozano

    PNAS August 27, 2019 116 (35) 17429-17437; first published August 13, 2019. https://doi.org/10.1073/pnas.1909550116
  • Open Access

    MiR223-3p promotes synthetic lethality in BRCA1-deficient cancers

    Gayathri Srinivasan, Elizabeth A. Williamson, Kimi Kong, Aruna S. Jaiswal, Guangcun Huang, Hyun-Suk Kim, Orlando Schärer, Weixing Zhao, Sandeep Burma, Patrick Sung, and Robert Hromas

    PNAS August 27, 2019 116 (35) 17438-17443; first published August 8, 2019. https://doi.org/10.1073/pnas.1903150116
  • Open Access

    Histone H4 induces platelet ballooning and microparticle release during trauma hemorrhage

    Paul Vulliamy, Scarlett Gillespie, Paul C. Armstrong, Harriet E. Allan, Timothy D. Warner, and Karim Brohi

    PNAS August 27, 2019 116 (35) 17444-17449; first published August 12, 2019. https://doi.org/10.1073/pnas.1904978116
  • Open Access

    ARF6 and AMAP1 are major targets of KRAS and TP53 mutations to promote invasion, PD-L1 dynamics, and immune evasion of pancreatic cancer

    Shigeru Hashimoto, Shotaro Furukawa, Ari Hashimoto, Akio Tsutaho, Akira Fukao, Yurika Sakamura, Gyanu Parajuli, Yasuhito Onodera, Yutaro Otsuka, Haruka Handa, Tsukasa Oikawa, Soichiro Hata, Yoshihiro Nishikawa, Yusuke Mizukami, Yuzo Kodama, Masaaki Murakami, Toshinobu Fujiwara, Satoshi Hirano, and Hisataka Sabe

    PNAS August 27, 2019 116 (35) 17450-17459; first published August 9, 2019. https://doi.org/10.1073/pnas.1901765116
  • Open Access

    Enhanced adaptive immune responses in lung adenocarcinoma through natural killer cell stimulation

    Leah Schmidt, Banu Eskiocak, Ryan Kohn, Celeste Dang, Nikhil S. Joshi, Michel DuPage, Da-Yae Lee, and Tyler Jacks

    PNAS August 27, 2019 116 (35) 17460-17469; first published August 13, 2019. https://doi.org/10.1073/pnas.1904253116
  • Open Access

    iASPP mediates p53 selectivity through a modular mechanism fine-tuning DNA recognition

    Shuo Chen, Jiale Wu, Shan Zhong, Yuntong Li, Ping Zhang, Jingyi Ma, Jingshan Ren, Yun Tan, Yunhao Wang, Kin Fai Au, Christian Siebold, Gareth L. Bond, Zhu Chen, Min Lu, E. Yvonne Jones, and Xin Lu

    PNAS August 27, 2019 116 (35) 17470-17479; first published August 8, 2019. https://doi.org/10.1073/pnas.1909393116

• Microbiology

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    Toxoplasma gondii effector TgIST blocks type I interferon signaling to promote infection

    Sumit K. Matta, Philipp Olias, Zhou Huang, Qiuling Wang, Eugene Park, Wayne M. Yokoyama, and L. David Sibley

    PNAS August 27, 2019 116 (35) 17480-17491; first published August 14, 2019. https://doi.org/10.1073/pnas.1904637116
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    Alternative promoters drive human cytomegalovirus reactivation from latency

    Donna Collins-McMillen, Mike Rak, Jason C. Buehler, Suzu Igarashi-Hayes, Jeremy P. Kamil, Nathaniel J. Moorman, and Felicia Goodrum

    PNAS August 27, 2019 116 (35) 17492-17497; first published August 13, 2019. https://doi.org/10.1073/pnas.1900783116
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    Role of a patatin-like phospholipase in Plasmodium falciparum gametogenesis and malaria transmission

    Pallavi Singh, Aditi Alaganan, Kunal R. More, Audrey Lorthiois, Sabine Thiberge, Olivier Gorgette, Micheline Guillotte Blisnick, Julien Guglielmini, Shivani Shankar Aguilera, Lhousseine Touqui, Shailja Singh, and Chetan E. Chitnis

    PNAS August 27, 2019 116 (35) 17498-17508; first published August 14, 2019. https://doi.org/10.1073/pnas.1900266116

• Neuroscience

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    Learning active sensing strategies using a sensory brain–machine interface

    Andrew G. Richardson, Yohannes Ghenbot, Xilin Liu, Han Hao, Cole Rinehart, Sam DeLuccia, Solymar Torres Maldonado, Gregory Boyek, Milin Zhang, Firooz Aflatouni, Jan Van der Spiegel, and Timothy H. Lucas

    PNAS August 27, 2019 116 (35) 17509-17514; first published August 13, 2019. https://doi.org/10.1073/pnas.1909953116
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    Human GNPTAB stuttering mutations engineered into mice cause vocalization deficits and astrocyte pathology in the corpus callosum

    Tae-Un Han, Jessica Root, Laura D. Reyes, Elizabeth B. Huchinson, Johann du Hoffmann, Wang-Sik Lee, Terra D. Barnes, and Dennis Drayna

    PNAS August 27, 2019 116 (35) 17515-17524; first published August 12, 2019. https://doi.org/10.1073/pnas.1901480116

• Pharmacology

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    Structure and dynamics of G protein-coupled receptor–bound ghrelin reveal the critical role of the octanoyl chain

    Guillaume Ferré, Maxime Louet, Oliver Saurel, Bartholomé Delort, Georges Czaplicki, Céline M’Kadmi, Marjorie Damian, Pedro Renault, Sonia Cantel, Laurent Gavara, Pascal Demange, Jacky Marie, Jean-Alain Fehrentz, Nicolas Floquet, Alain Milon, and Jean-Louis Banères

    PNAS August 27, 2019 116 (35) 17525-17530; first published August 15, 2019. https://doi.org/10.1073/pnas.1905105116
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    Upregulation of reduced folate carrier by vitamin D enhances brain folate uptake in mice lacking folate receptor alpha

    Camille Alam, Susanne Aufreiter, Constantine J. Georgiou, Md. Tozammel Hoque, Richard H. Finnell, Deborah L. O’Connor, I. David Goldman, and Reina Bendayan

    PNAS August 27, 2019 116 (35) 17531-17540; first published August 12, 2019. https://doi.org/10.1073/pnas.1907077116

• Physiology

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    Akt phosphorylation of neuronal nitric oxide synthase regulates gastrointestinal motility in mouse ileum

    Damian D. Guerra, Rachael Bok, Vibhuti Vyas, David J. Orlicky, Ramón A. Lorca, and K. Joseph Hurt

    PNAS August 27, 2019 116 (35) 17541-17546; first published August 12, 2019. https://doi.org/10.1073/pnas.1905902116
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    Piezo2 integrates mechanical and thermal cues in vertebrate mechanoreceptors

    Wang Zheng, Yury A. Nikolaev, Elena O. Gracheva, and Sviatoslav N. Bagriantsev

    PNAS August 27, 2019 116 (35) 17547-17555; first published August 14, 2019. https://doi.org/10.1073/pnas.1910213116

• Plant Biology

  • Open Access

    Regulation of photoprotection gene expression in Chlamydomonas by a putative E3 ubiquitin ligase complex and a homolog of CONSTANS

    Stéphane T. Gabilly, Christopher R. Baker, Setsuko Wakao, Thien Crisanto, Katharine Guan, Ke Bi, Elodie Guiet, Carmela R. Guadagno, and Krishna K. Niyogi

    PNAS August 27, 2019 116 (35) 17556-17562; first published August 12, 2019. https://doi.org/10.1073/pnas.1821689116
  • Open Access

    The catalytic core of DEMETER guides active DNA demethylation in Arabidopsis

    Changqing Zhang, Yu-Hung Hung, Hyun Jung Rim, Dapeng Zhang, Jennifer M. Frost, Hosub Shin, Hosung Jang, Fang Liu, Wenyan Xiao, Lakshminarayan M. Iyer, L. Aravind, Xiang-Qian Zhang, Robert L. Fischer, Jin Hoe Huh, and Tzung-Fu Hsieh

    PNAS August 27, 2019 116 (35) 17563-17571; first published August 13, 2019. https://doi.org/10.1073/pnas.1907290116
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    Phosphorylation-guarded light-harvesting complex II contributes to broad-spectrum blast resistance in rice

    Muxing Liu, Suobing Zhang, Jiexiong Hu, Wenxian Sun, Jonas Padilla, Yanglan He, Ying Li, Ziyi Yin, Xinyu Liu, Wenhao Wang, Danyu Shen, Dayong Li, Haifeng Zhang, Xiaobo Zheng, Zhongli Cui, Guo-Liang Wang, Ping Wang, Bo Zhou, and Zhengguang Zhang

    PNAS August 27, 2019 116 (35) 17572-17577; first published August 12, 2019. https://doi.org/10.1073/pnas.1905123116
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    Dynamic regulation of chromatin topology and transcription by inverted repeat-derived small RNAs in sunflower

    Delfina Gagliardi, Damian A. Cambiagno, Agustin L. Arce, Ariel H. Tomassi, Jorge I. Giacomelli, Federico D. Ariel, and Pablo A. Manavella

    PNAS August 27, 2019 116 (35) 17578-17583; first published August 13, 2019. https://doi.org/10.1073/pnas.1903131116
  • Open Access

    Arabidopsis BRUTUS-LIKE E3 ligases negatively regulate iron uptake by targeting transcription factor FIT for recycling

    Jorge Rodríguez-Celma, James M. Connorton, Inga Kruse, Robert T. Green, Marina Franceschetti, Yi-Tze Chen, Yan Cui, Hong-Qing Ling, Kuo-Chen Yeh, and Janneke Balk

    PNAS August 27, 2019 116 (35) 17584-17591; first published August 14, 2019. https://doi.org/10.1073/pnas.1907971116

• Systems Biology

  • Open Access

    Energy metabolism controls phenotypes by protein efficiency and allocation

    Yu Chen and Jens Nielsen

    PNAS August 27, 2019 116 (35) 17592-17597; first published August 12, 2019. https://doi.org/10.1073/pnas.1906569116