Proceedings of the National Academy of Sciences: 116 (42)

New Research In

October 15, 2019; vol. 116 no. 42

This Week in PNAS

You have access
In This Issue
PNAS October 15, 2019 116 (42) 20797-20799; https://doi.org/10.1073/iti4219116

Core Concepts

A brief introduction to emerging topics in science.

You have access
Core Concept: Blockchain offers applications well beyond Bitcoin but faces its own limitations
Front Matter
Stephen Ornes

PNAS October 15, 2019 116 (42) 20800-20803; https://doi.org/10.1073/pnas.1914849116

Commentaries

You have access
Messenger RNA therapy as an option for treating metabolic disorders
Randy J. Chandler

PNAS October 15, 2019 116 (42) 20804-20806; first published September 19, 2019. https://doi.org/10.1073/pnas.1914673116
You have access
Forgetting memories through distinct actin remodeling mechanisms
Kuan-Lin Feng and Ann-Shyn Chiang

PNAS October 15, 2019 116 (42) 20807-20808; first published September 17, 2019. https://doi.org/10.1073/pnas.1914578116

Letters

You have access
On the multibin logarithmic score used in the FluSight competitions
Johannes Bracher

PNAS October 15, 2019 116 (42) 20809-20810; first published September 26, 2019. https://doi.org/10.1073/pnas.1912147116
Open Access
Reply to Bracher: Scoring probabilistic forecasts to maximize public health interpretability
Nicholas G. Reich, Dave Osthus, Evan L. Ray, Teresa K. Yamana, Matthew Biggerstaff, Michael A. Johansson, Roni Rosenfeld, and Jeffrey Shaman

PNAS October 15, 2019 116 (42) 20811-20812; first published September 26, 2019. https://doi.org/10.1073/pnas.1912694116
You have access
Reward prediction tells us less than expected about musical pleasure
Rémi de Fleurian, Peter M. C. Harrison, Marcus T. Pearce, and David R. Quiroga-Martinez

PNAS October 15, 2019 116 (42) 20813-20814; first published September 19, 2019. https://doi.org/10.1073/pnas.1913244116
You have access
Reply to de Fleurian et al.: Toward a fuller understanding of reward prediction errors and their role in musical pleasure
Benjamin P. Gold, Ernest Mas-Herrero, Alain Dagher, and Robert J. Zatorre

PNAS October 15, 2019 116 (42) 20815-20816; first published September 19, 2019. https://doi.org/10.1073/pnas.1913835116

Brief Report

Open Access
A triple drug combination targeting components of the nutrient-sensing network maximizes longevity
Jorge Iván Castillo-Quan, Luke S. Tain, Kerri J. Kinghorn, Li Li, Sebastian Grönke, Yvonne Hinze, T. Keith Blackwell, Ivana Bjedov, and Linda Partridge

PNAS October 15, 2019 116 (42) 20817-20819; first published September 30, 2019. https://doi.org/10.1073/pnas.1913212116

Physical Sciences

Applied Physical Sciences
- Open Access
  Wildfire prevention through prophylactic treatment of high-risk landscapes using viscoelastic retardant fluids
  Anthony C. Yu, Hector Lopez Hernandez, Andrew H. Kim, Lyndsay M. Stapleton, Ruben J. Brand, Eric T. Mellor, Cameron P. Bauer, Gregory D. McCurdy, Albert J. Wolff III, Doreen Chan, Craig S. Criddle, Jesse D. Acosta, and Eric A. Appel
  
  PNAS October 15, 2019 116 (42) 20820-20827; first published September 30, 2019. https://doi.org/10.1073/pnas.1907855116
- You have access
  A general constitutive model for dense, fine-particle suspensions validated in many geometries
  Aaron S. Baumgarten and Ken Kamrin
  
  PNAS October 15, 2019 116 (42) 20828-20836; first published September 27, 2019. https://doi.org/10.1073/pnas.1908065116
- You have access
  Rationally engineered Staphylococcus aureus Cas9 nucleases with high genome-wide specificity
  Yuanyan Tan, Athena H. Y. Chu, Siyu Bao, Duc Anh Hoang, Firaol Tamiru Kebede, Wenjun Xiong, Mingfang Ji, Jiahai Shi, and Zongli Zheng
  
  PNAS October 15, 2019 116 (42) 20969-20976; first published September 30, 2019. https://doi.org/10.1073/pnas.1906843116
Biophysics and Computational Biology
- You have access
  Structure of a C₂S₂M₂N₂-type PSII–LHCII supercomplex from the green alga Chlamydomonas reinhardtii
  Liangliang Shen, Zihui Huang, Shenghai Chang, Wenda Wang, Jingfen Wang, Tingyun Kuang, Guangye Han, Jian-Ren Shen, and Xing Zhang
  
  PNAS October 15, 2019 116 (42) 21246-21255; first published September 30, 2019. https://doi.org/10.1073/pnas.1912462116
Chemistry
- You have access
  Intact carbonic acid is a viable protonating agent for biological bases
  Daniel Aminov, Dina Pines, Philip M. Kiefer, Snehasis Daschakraborty, James T. Hynes, and Ehud Pines
  
  PNAS October 15, 2019 116 (42) 20837-20843; first published September 30, 2019. https://doi.org/10.1073/pnas.1909498116
- You have access
  Waterproof molecular monolayers stabilize 2D materials
  Cong Su, Zongyou Yin, Qing-Bo Yan, Zegao Wang, Hongtao Lin, Lei Sun, Wenshuo Xu, Tetsuya Yamada, Xiang Ji, Nobuyuki Zettsu, Katsuya Teshima, Jamie H. Warner, Mircea Dincă, Juejun Hu, Mingdong Dong, Gang Su, Jing Kong, and Ju Li
  
  PNAS October 15, 2019 116 (42) 20844-20849; first published October 1, 2019. https://doi.org/10.1073/pnas.1909500116
- You have access
  The binuclear cluster of [FeFe] hydrogenase is formed with sulfur donated by cysteine of an [Fe(Cys)(CO)₂(CN)] organometallic precursor
  Guodong Rao, Scott A. Pattenaude, Katherine Alwan, Ninian J. Blackburn, R. David Britt, and Thomas B. Rauchfuss
  
  PNAS October 15, 2019 116 (42) 20850-20855; first published September 30, 2019. https://doi.org/10.1073/pnas.1913324116
- You have access
  Theory and simulations for RNA folding in mixtures of monovalent and divalent cations
  Hung T. Nguyen, Naoto Hori, and D. Thirumalai
  
  PNAS October 15, 2019 116 (42) 21022-21030; first published September 30, 2019. https://doi.org/10.1073/pnas.1911632116
- You have access
  Photopotentiation of the GABA_A receptor with caged diazepam
  Lorenzo Sansalone, Joshua Bratsch-Prince, Sicheng Tang, Burjor Captain, David D. Mott, and Françisco M. Raymo
  
  PNAS October 15, 2019 116 (42) 21176-21184; first published October 1, 2019. https://doi.org/10.1073/pnas.1902383116
Engineering
- You have access
  Shape-shifting structured lattices via multimaterial 4D printing
  J. William Boley, Wim M. van Rees, Charles Lissandrello, Mark N. Horenstein, Ryan L. Truby, Arda Kotikian, Jennifer A. Lewis, and L. Mahadevan
  
  PNAS October 15, 2019 116 (42) 20856-20862; first published October 2, 2019. https://doi.org/10.1073/pnas.1908806116
- You have access
  Multibioinspired slippery surfaces with wettable bump arrays for droplets pumping
  Xiaoxuan Zhang, Lingyu Sun, Yu Wang, Feika Bian, Yuetong Wang, and Yuanjin Zhao
  
  PNAS October 15, 2019 116 (42) 20863-20868; first published September 30, 2019. https://doi.org/10.1073/pnas.1912467116
Environmental Sciences
- You have access
  Rapid increase in Asian bottles in the South Atlantic Ocean indicates major debris inputs from ships
  From the Cover
  
  Peter G. Ryan, Ben J. Dilley, Robert A. Ronconi, and Maëlle Connan
  
  PNAS October 15, 2019 116 (42) 20892-20897; first published September 30, 2019. https://doi.org/10.1073/pnas.1909816116
Physics
- You have access
  Intrinsically undamped plasmon modes in narrow electron bands
  Cyprian Lewandowski and Leonid Levitov
  
  PNAS October 15, 2019 116 (42) 20869-20874; first published September 27, 2019. https://doi.org/10.1073/pnas.1909069116
- Open Access
  Dynamics of wrinkling in ultrathin elastic sheets
  From the Cover
  
  Finn Box, Doireann O’Kiely, Ousmane Kodio, Maxime Inizan, Alfonso A. Castrejón-Pita, and Dominic Vella
  
  PNAS October 15, 2019 116 (42) 20875-20880; first published September 30, 2019. https://doi.org/10.1073/pnas.1905755116
Statistics
- Open Access
  Sampling can be faster than optimization
  Yi-An Ma, Yuansi Chen, Chi Jin, Nicolas Flammarion, and Michael I. Jordan
  
  PNAS October 15, 2019 116 (42) 20881-20885; first published September 30, 2019. https://doi.org/10.1073/pnas.1820003116

Biological Sciences

Agricultural Sciences
- You have access
  Reviving rare chicken breeds using genetically engineered sterility in surrogate host birds
  Mark E. Woodcock, Almas A. Gheyas, Andrew S. Mason, Sunil Nandi, Lorna Taylor, Adrian Sherman, Jacqueline Smith, Dave W. Burt, Rachel Hawken, and Michael J. McGrew
  
  PNAS October 15, 2019 116 (42) 20930-20937; first published October 1, 2019. https://doi.org/10.1073/pnas.1906316116
- Open Access
  Xanthomonas translucens commandeers the host rate-limiting step in ABA biosynthesis for disease susceptibility
  Zhao Peng, Ying Hu, Junli Zhang, Jose C. Huguet-Tapia, Anna K. Block, Sunghun Park, Suraj Sapkota, Zhaohui Liu, Sanzhen Liu, and Frank F. White
  
  PNAS October 15, 2019 116 (42) 20938-20946; first published October 1, 2019. https://doi.org/10.1073/pnas.1911660116
Applied Biological Sciences
- Open Access
  Engineering the stereoisomeric structure of seed oil to mimic human milk fat
  Harrie van Erp, Fiona M. Bryant, Jose Martin-Moreno, Louise V. Michaelson, Govindprasad Bhutada, and Peter J. Eastmond
  
  PNAS October 15, 2019 116 (42) 20947-20952; first published September 30, 2019. https://doi.org/10.1073/pnas.1907915116
- Open Access
  A large-scale study reveals 24-h operational rhythms in hospital treatment
  Marc D. Ruben, Lauren J. Francey, Yuping Guo, Gang Wu, Edward B. Cooper, Amy S. Shah, John B. Hogenesch, and David F. Smith
  
  PNAS October 15, 2019 116 (42) 20953-20958; first published October 1, 2019. https://doi.org/10.1073/pnas.1909557116
- You have access
  Francisella novicida Cas9 interrogates genomic DNA with very high specificity and can be used for mammalian genome editing
  Sundaram Acharya, Arpit Mishra, Deepanjan Paul, Asgar Hussain Ansari, Mohd. Azhar, Manoj Kumar, Riya Rauthan, Namrata Sharma, Meghali Aich, Dipanjali Sinha, Saumya Sharma, Shivani Jain, Arjun Ray, Suman Jain, Sivaprakash Ramalingam, Souvik Maiti, and Debojyoti Chakraborty
  
  PNAS October 15, 2019 116 (42) 20959-20968; first published September 30, 2019. https://doi.org/10.1073/pnas.1818461116
Biochemistry
- You have access
  Rationally engineered Staphylococcus aureus Cas9 nucleases with high genome-wide specificity
  Yuanyan Tan, Athena H. Y. Chu, Siyu Bao, Duc Anh Hoang, Firaol Tamiru Kebede, Wenjun Xiong, Mingfang Ji, Jiahai Shi, and Zongli Zheng
  
  PNAS October 15, 2019 116 (42) 20969-20976; first published September 30, 2019. https://doi.org/10.1073/pnas.1906843116
- Open Access
  Rotational symmetry of the structured Chip/LDB-SSDP core module of the Wnt enhanceosome
  Miha Renko, Marc Fiedler, Trevor J. Rutherford, Jonas V. Schaefer, Andreas Plückthun, and Mariann Bienz
  
  PNAS October 15, 2019 116 (42) 20977-20983; first published September 30, 2019. https://doi.org/10.1073/pnas.1912705116
- Open Access
  Structural basis of light-induced redox regulation in the Calvin–Benson cycle in cyanobacteria
  Ciaran R. McFarlane, Nita R. Shah, Burak V. Kabasakal, Blanca Echeverria, Charles A. R. Cotton, Doryen Bubeck, and James W. Murray
  
  PNAS October 15, 2019 116 (42) 20984-20990; first published September 30, 2019. https://doi.org/10.1073/pnas.1906722116
- You have access
  A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels
  Kaalak Reddy, Jana R. Jenquin, Ona L. McConnell, John D. Cleary, Jared I. Richardson, Belinda S. Pinto, Maja C. Haerle, Elizabeth Delgado, Lori Planco, Masayuki Nakamori, Eric T. Wang, and J. Andrew Berglund
  
  PNAS October 15, 2019 116 (42) 20991-21000; first published September 30, 2019. https://doi.org/10.1073/pnas.1901893116
- You have access
  Mapping low-affinity/high-specificity peptide–protein interactions using ligand-footprinting mass spectrometry
  Benjamin W. Parker, Edward J. Goncz, David T. Krist, Alexander V. Statsyuk, Alexey I. Nesvizhskii, and Eric L. Weiss
  
  PNAS October 15, 2019 116 (42) 21001-21011; first published October 2, 2019. https://doi.org/10.1073/pnas.1819533116
- You have access
  Overcoming insecticide resistance through computational inhibitor design
  Galen J. Correy, Daniel Zaidman, Alon Harmelin, Silvia Carvalho, Peter D. Mabbitt, Viviane Calaora, Peter J. James, Andrew C. Kotze, Colin J. Jackson, and Nir London
  
  PNAS October 15, 2019 116 (42) 21012-21021; first published October 1, 2019. https://doi.org/10.1073/pnas.1909130116
Biophysics and Computational Biology
- You have access
  Theory and simulations for RNA folding in mixtures of monovalent and divalent cations
  Hung T. Nguyen, Naoto Hori, and D. Thirumalai
  
  PNAS October 15, 2019 116 (42) 21022-21030; first published September 30, 2019. https://doi.org/10.1073/pnas.1911632116
- You have access
  How internal cavities destabilize a protein
  Mengjun Xue, Takuro Wakamoto, Camilla Kejlberg, Yuichi Yoshimura, Tania Aaquist Nielsen, Michael Wulff Risør, Kristian Wejse Sanggaard, Ryo Kitahara, and Frans A. A. Mulder
  
  PNAS October 15, 2019 116 (42) 21031-21036; first published September 30, 2019. https://doi.org/10.1073/pnas.1911181116
- You have access
  Capsid expansion of bacteriophage T5 revealed by high resolution cryoelectron microscopy
  Alexis Huet, Robert L. Duda, Pascale Boulanger, and James F. Conway
  
  PNAS October 15, 2019 116 (42) 21037-21046; first published October 2, 2019. https://doi.org/10.1073/pnas.1909645116
Developmental Biology
- You have access
  Paternal knockout of Slc38a4/SNAT4 causes placental hypoplasia associated with intrauterine growth restriction in mice
  Shogo Matoba, Shoko Nakamuta, Kento Miura, Michiko Hirose, Hirosuke Shiura, Takashi Kohda, Nobuaki Nakamuta, and Atsuo Ogura
  
  PNAS October 15, 2019 116 (42) 21047-21053; first published September 30, 2019. https://doi.org/10.1073/pnas.1907884116
- You have access
  β-Catenin is required for radial cell patterning and identity in the developing mouse cochlea
  Lina Jansson, Michael Ebeid, Jessica W. Shen, Tara E. Mokhtari, Lee A. Quiruz, David M. Ornitz, Sung-Ho Huh, and Alan G. Cheng
  
  PNAS October 15, 2019 116 (42) 21054-21060; first published September 30, 2019. https://doi.org/10.1073/pnas.1910223116
Ecology
- You have access
  The conflict between adaptation and dispersal for maintaining biodiversity in changing environments
  Patrick L. Thompson and Emanuel A. Fronhofer
  
  PNAS October 15, 2019 116 (42) 21061-21067; first published September 30, 2019. https://doi.org/10.1073/pnas.1911796116
Evolution
- Open Access
  On the feasibility of saltational evolution
  Mikhail I. Katsnelson, Yuri I. Wolf, and Eugene V. Koonin
  
  PNAS October 15, 2019 116 (42) 21068-21075; first published September 30, 2019. https://doi.org/10.1073/pnas.1909031116
- Open Access
  Multiple modes of convergent adaptation in the spread of glyphosate-resistant Amaranthus tuberculatus
  Julia M. Kreiner, Darci Ann Giacomini, Felix Bemm, Bridgit Waithaka, Julian Regalado, Christa Lanz, Julia Hildebrandt, Peter H. Sikkema, Patrick J. Tranel, Detlef Weigel, John R. Stinchcombe, and Stephen I. Wright
  
  PNAS October 15, 2019 116 (42) 21076-21084; first published September 30, 2019. https://doi.org/10.1073/pnas.1900870116
- You have access
  Empirical measures of mutational effects define neutral models of regulatory evolution in Saccharomyces cerevisiae
  Andrea Hodgins-Davis, Fabien Duveau, Elizabeth A. Walker, and Patricia J. Wittkopp
  
  PNAS October 15, 2019 116 (42) 21085-21093; first published September 30, 2019. https://doi.org/10.1073/pnas.1902823116
- You have access
  A functional enrichment test for molecular convergent evolution finds a clear protein-coding signal in echolocating bats and whales
  Amir Marcovitz, Yatish Turakhia, Heidi I. Chen, Michael Gloudemans, Benjamin A. Braun, Haoqing Wang, and Gill Bejerano
  
  PNAS October 15, 2019 116 (42) 21094-21103; first published September 30, 2019. https://doi.org/10.1073/pnas.1818532116
- You have access
  Allele-specific nonstationarity in evolution of influenza A virus surface proteins
  Anfisa V. Popova, Ksenia R. Safina, Vasily V. Ptushenko, Anastasia V. Stolyarova, Alexander V. Favorov, Alexey D. Neverov, and Georgii A. Bazykin
  
  PNAS October 15, 2019 116 (42) 21104-21112; first published October 2, 2019. https://doi.org/10.1073/pnas.1904246116
Immunology and Inflammation
- You have access
  Cowpox virus encodes a protein that binds B7.1 and B7.2 and subverts T cell costimulation
  Xiaoli Wang, Sytse J. Piersma, Jabari I. Elliott, John M. Errico, Maria D. Gainey, Liping Yang, Christopher A. Nelson, Wayne M. Yokoyama, and Daved H. Fremont
  
  PNAS October 15, 2019 116 (42) 21113-21119; first published October 1, 2019. https://doi.org/10.1073/pnas.1909414116
- You have access
  IL-2 receptors preassemble and signal in the ER/Golgi causing resistance to antiproliferative anti–IL-2Rα therapies
  Julianna Volkó, Ádám Kenesei, Meili Zhang, Péter Várnai, Gábor Mocsár, Michael N. Petrus, Károly Jambrovics, Zoltán Balajthy, Gabriele Müller, Andrea Bodnár, Katalin Tóth, Thomas A. Waldmann, and György Vámosi
  
  PNAS October 15, 2019 116 (42) 21120-21130; first published September 30, 2019. https://doi.org/10.1073/pnas.1901382116
- Open Access
  Extrapituitary prolactin promotes generation of Eomes-positive helper T cells mediating neuroinflammation
  Chenyang Zhang, Ben J. E. Raveney, Hirohiko Hohjoh, Chiharu Tomi, Shinji Oki, and Takashi Yamamura
  
  PNAS October 15, 2019 116 (42) 21131-21139; first published September 30, 2019. https://doi.org/10.1073/pnas.1906438116
- You have access
  RORα is crucial for attenuated inflammatory response to maintain intestinal homeostasis
  Se Kyu Oh, Dongha Kim, Kyeongkyu Kim, Kyungjin Boo, Young Suk Yu, Ik Soo Kim, Yoon Jeon, Sun-Kyoung Im, Su-Hyung Lee, Ji Min Lee, Younhee Ko, Ho Lee, Daechan Park, Sungsoon Fang, and Sung Hee Baek
  
  PNAS October 15, 2019 116 (42) 21140-21149; first published September 30, 2019. https://doi.org/10.1073/pnas.1907595116
Medical Sciences
- You have access
  Lipid nanoparticle-targeted mRNA therapy as a treatment for the inherited metabolic liver disorder arginase deficiency
  From the Cover
  
  Brian Truong, Gabriella Allegri, Xiao-Bo Liu, Kristine E. Burke, Xuling Zhu, Stephen D. Cederbaum, Johannes Häberle, Paolo G. V. Martini, and Gerald S. Lipshutz
  
  PNAS October 15, 2019 116 (42) 21150-21159; first published September 9, 2019. https://doi.org/10.1073/pnas.1906182116
Microbiology
- Open Access
  Genetic ablation of purine salvage in Cryptosporidium parvum reveals nucleotide uptake from the host cell
  Mattie C. Pawlowic, Mastanbabu Somepalli, Adam Sateriale, Gillian T. Herbert, Alexis R. Gibson, Gregory D. Cuny, Lizbeth Hedstrom, and Boris Striepen
  
  PNAS October 15, 2019 116 (42) 21160-21165; first published September 30, 2019. https://doi.org/10.1073/pnas.1908239116
- You have access
  The cbb₃-type cytochrome oxidase assembly factor CcoG is a widely distributed cupric reductase
  Dorian Marckmann, Petru-Iulian Trasnea, Johannes Schimpf, Christine Winterstein, Andreea Andrei, Stefan Schmollinger, Crysten E. Blaby-Haas, Thorsten Friedrich, Fevzi Daldal, and Hans-Georg Koch
  
  PNAS October 15, 2019 116 (42) 21166-21175; first published September 30, 2019. https://doi.org/10.1073/pnas.1913803116
Neuroscience
- You have access
  Photopotentiation of the GABA_A receptor with caged diazepam
  Lorenzo Sansalone, Joshua Bratsch-Prince, Sicheng Tang, Burjor Captain, David D. Mott, and Françisco M. Raymo
  
  PNAS October 15, 2019 116 (42) 21176-21184; first published October 1, 2019. https://doi.org/10.1073/pnas.1902383116
- You have access
  Laminar specific fMRI reveals directed interactions in distributed networks during language processing
  Daniel Sharoh, Tim van Mourik, Lauren J. Bains, Katrien Segaert, Kirsten Weber, Peter Hagoort, and David G. Norris
  
  PNAS October 15, 2019 116 (42) 21185-21190; first published September 30, 2019. https://doi.org/10.1073/pnas.1907858116
- Open Access
  Genetic dissection of active forgetting in labile and consolidated memories in Drosophila
  From the Cover
  
  Yang Gao, Yichun Shuai, Xuchen Zhang, Yuwei Peng, Lianzhang Wang, Jing He, Yi Zhong, and Qian Li
  
  PNAS October 15, 2019 116 (42) 21191-21197; first published September 5, 2019. https://doi.org/10.1073/pnas.1903763116
- Open Access
  Amyloid-beta impairs TOM1-mediated IL-1R1 signaling
  Alessandra Cadete Martini, Angela Gomez-Arboledas, Stefania Forner, Carlos J. Rodriguez-Ortiz, Amanda McQuade, Emma Danhash, Jimmy Phan, Dominic Javonillo, Jordan-Vu Ha, Melanie Tram, Laura Trujillo-Estrada, Celia da Cunha, Rahasson R. Ager, Jose C. Davila, Masashi Kitazawa, Mathew Blurton-Jones, Antonia Gutierrez, David Baglietto-Vargas, Rodrigo Medeiros, and Frank M. LaFerla
  
  PNAS October 15, 2019 116 (42) 21198-21206; first published September 30, 2019. https://doi.org/10.1073/pnas.1914088116
- You have access
  N-terminal alternative splicing of GluN1 regulates the maturation of excitatory synapses and seizure susceptibility
  Hong Liu, Hao Wang, Matthew Peterson, Wen Zhang, Guoqiang Hou, and Zhong-wei Zhang
  
  PNAS October 15, 2019 116 (42) 21207-21212; first published September 30, 2019. https://doi.org/10.1073/pnas.1905721116
- You have access
  Gray Matter Age Prediction as a Biomarker for Risk of Dementia
  Johnny Wang, Maria J. Knol, Aleksei Tiulpin, Florian Dubost, Marleen de Bruijne, Meike W. Vernooij, Hieab H. H. Adams, M. Arfan Ikram, Wiro J. Niessen, and Gennady V. Roshchupkin
  
  PNAS October 15, 2019 116 (42) 21213-21218; first published October 1, 2019. https://doi.org/10.1073/pnas.1902376116
- Open Access
  Gradients of structure–function tethering across neocortex
  Bertha Vázquez-Rodríguez, Laura E. Suárez, Ross D. Markello, Golia Shafiei, Casey Paquola, Patric Hagmann, Martijn P. van den Heuvel, Boris C. Bernhardt, R. Nathan Spreng, and Bratislav Misic
  
  PNAS October 15, 2019 116 (42) 21219-21227; first published September 30, 2019. https://doi.org/10.1073/pnas.1903403116
- Open Access
  Muscle acetylcholine receptor conversion into chloride conductance at positive potentials by a single mutation
  Hakan Cetin, Max Epstein, Wei W. Liu, Susan Maxwell, Pedro M. Rodriguez Cruz, Judith Cossins, Angela Vincent, Richard Webster, Philip C. Biggin, and David Beeson
  
  PNAS October 15, 2019 116 (42) 21228-21235; first published September 30, 2019. https://doi.org/10.1073/pnas.1908284116
Pharmacology
- You have access
  KCNQ5 activation is a unifying molecular mechanism shared by genetically and culturally diverse botanical hypotensive folk medicines
  Rían W. Manville, Jennifer van der Horst, Kaitlyn E. Redford, Benjamin B. Katz, Thomas A. Jepps, and Geoffrey W. Abbott
  
  PNAS October 15, 2019 116 (42) 21236-21245; first published September 30, 2019. https://doi.org/10.1073/pnas.1907511116
Plant Biology
- You have access
  Structure of a C₂S₂M₂N₂-type PSII–LHCII supercomplex from the green alga Chlamydomonas reinhardtii
  Liangliang Shen, Zihui Huang, Shenghai Chang, Wenda Wang, Jingfen Wang, Tingyun Kuang, Guangye Han, Jian-Ren Shen, and Xing Zhang
  
  PNAS October 15, 2019 116 (42) 21246-21255; first published September 30, 2019. https://doi.org/10.1073/pnas.1912462116
- You have access
  Mining for protein S-sulfenylation in Arabidopsis uncovers redox-sensitive sites
  Jingjing Huang, Patrick Willems, Bo Wei, Caiping Tian, Renan B. Ferreira, Nandita Bodra, Santiago Agustín Martínez Gache, Khadija Wahni, Keke Liu, Didier Vertommen, Kris Gevaert, Kate S. Carroll, Marc Van Montagu, Jing Yang, Frank Van Breusegem, and Joris Messens
  
  PNAS October 15, 2019 116 (42) 21256-21261; first published October 2, 2019. https://doi.org/10.1073/pnas.1906768116
- Open Access
  GWAS with principal component analysis identifies a gene comprehensively controlling rice architecture
  Kenji Yano, Yoichi Morinaka, Fanmiao Wang, Peng Huang, Sayaka Takehara, Takaaki Hirai, Aya Ito, Eriko Koketsu, Mayuko Kawamura, Kunihiko Kotake, Shinya Yoshida, Masaki Endo, Gen Tamiya, Hidemi Kitano, Miyako Ueguchi-Tanaka, Ko Hirano, and Makoto Matsuoka
  
  PNAS October 15, 2019 116 (42) 21262-21267; first published September 30, 2019. https://doi.org/10.1073/pnas.1904964116
- Open Access
  Light-inducible expression of translation factor EF-Tu during acclimation to strong light enhances the repair of photosystem II
  Haruhiko Jimbo, Taichi Izuhara, Yukako Hihara, Toru Hisabori, and Yoshitaka Nishiyama
  
  PNAS October 15, 2019 116 (42) 21268-21273; first published September 30, 2019. https://doi.org/10.1073/pnas.1909520116
- Open Access
  Salicylic acid-mediated plasmodesmal closure via Remorin-dependent lipid organization
  Dingquan Huang, Yanbiao Sun, Zhiming Ma, Meiyu Ke, Yong Cui, Zichen Chen, Chaofan Chen, Changyang Ji, Tuan Minh Tran, Liang Yang, Sin Man Lam, Yanhong Han, Guanghou Shu, Jiří Friml, Yansong Miao, Liwen Jiang, and Xu Chen
  
  PNAS October 15, 2019 116 (42) 21274-21284; first published October 1, 2019. https://doi.org/10.1073/pnas.1911892116
- You have access
  Noncanonical auxin signaling regulates cell division pattern during lateral root development
  Rongfeng Huang, Rui Zheng, Jun He, Zimin Zhou, Jiacheng Wang, Yan Xiong, and Tongda Xu
  
  PNAS October 15, 2019 116 (42) 21285-21290; first published September 30, 2019. https://doi.org/10.1073/pnas.1910916116
- You have access
  Interaction between VPS35 and RABG3f is necessary as a checkpoint to control fusion of late compartments with the vacuole
  Cecilia Rodriguez-Furlan, David Domozych, Weixing Qian, Per-Anders Enquist, Xiaohui Li, Chunhua Zhang, Rolf Schenk, Holly Saulsbery Winbigler, William Jackson, Natasha V. Raikhel, and Glenn R. Hicks
  
  PNAS October 15, 2019 116 (42) 21291-21301; first published September 30, 2019. https://doi.org/10.1073/pnas.1905321116
Population Biology
- You have access
  Contemporary evolution of maize landraces and their wild relatives influenced by gene flow with modern maize varieties
  Idalia C. Rojas-Barrera, Ana Wegier, José de Jesús Sánchez González, Gregory L. Owens, Loren H. Rieseberg, and Daniel Piñero
  
  PNAS October 15, 2019 116 (42) 21302-21311; first published September 30, 2019. https://doi.org/10.1073/pnas.1817664116
Psychological and Cognitive Sciences
- You have access
  Distinct representations of spatial and categorical relationships across human scene-selective cortex
  Andrew S. Persichetti and Daniel D. Dilks
  
  PNAS October 15, 2019 116 (42) 21312-21317; first published September 30, 2019. https://doi.org/10.1073/pnas.1903057116
- Open Access
  Neural dynamics of semantic composition
  Bingjiang Lyu, Hun S. Choi, William D. Marslen-Wilson, Alex Clarke, Billi Randall, and Lorraine K. Tyler
  
  PNAS October 15, 2019 116 (42) 21318-21327; first published September 30, 2019. https://doi.org/10.1073/pnas.1903402116

Corrections

You have access
Correction for Manca et al., SNARE machinery is optimized for ultrafast fusion
PNAS October 15, 2019 116 (42) 21328-21329; first published October 7, 2019. https://doi.org/10.1073/pnas.1915891116
You have access
Correction for Sotoudeh et al., Effects of the peer metagenomic environment on smoking behavior
PNAS October 15, 2019 116 (42) 21330; first published October 7, 2019. https://doi.org/10.1073/pnas.1916279116
You have access
Correction for Ishii et al., MPE-seq, a new method for the genome-wide analysis of chromatin structure
PNAS October 15, 2019 116 (42) 21331; first published October 7, 2019. https://doi.org/10.1073/pnas.1916397116
You have access
Correction for Font-Muñoz et al., Collective sinking promotes selective cell pairing in planktonic pennate diatoms
PNAS October 15, 2019 116 (42) 21332; first published October 7, 2019. https://doi.org/10.1073/pnas.1916096116

Main menu

User menu

Search

New Research In

Table of Contents

This Week in PNAS

Core Concepts

Commentaries

Letters

Brief Report

Physical Sciences

Applied Physical Sciences

Biophysics and Computational Biology

Chemistry

Engineering

Environmental Sciences

Physics

Statistics

Biological Sciences

Agricultural Sciences

Applied Biological Sciences

Biochemistry

Biophysics and Computational Biology

Developmental Biology

Ecology

Evolution

Immunology and Inflammation

Medical Sciences

Microbiology

Neuroscience

Pharmacology

Plant Biology

Population Biology

Psychological and Cognitive Sciences

Corrections

In this issue

Jump to

Articles

PNAS Portals

Information

Main menu

User menu

Search

New Research In

Physical Sciences

Featured Portals

Articles by Topic

Social Sciences

Featured Portals

Articles by Topic

Biological Sciences

Featured Portals

Articles by Topic

Table of Contents

This Week in PNAS

Core Concepts

Commentaries

Letters

Brief Report

Physical Sciences

Applied Physical Sciences

Biophysics and Computational Biology

Chemistry

Engineering

Environmental Sciences

Physics

Statistics

Social Sciences

Economic Sciences

Environmental Sciences

Political Sciences

Psychological and Cognitive Sciences

Social Sciences

Sustainability Science

Biological Sciences

Agricultural Sciences

Applied Biological Sciences

Biochemistry

Biophysics and Computational Biology

Developmental Biology

Ecology

Evolution

Immunology and Inflammation

Medical Sciences

Microbiology

Neuroscience

Pharmacology

Plant Biology

Population Biology

Psychological and Cognitive Sciences

Corrections

In this issue

Jump to

Articles

PNAS Portals

Information