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Table of Contents
January 07, 2020; vol. 117 no. 1
Editorial
- You have accessOn a subject no one wants to read about (about which no one wants to read?)May R. Berenbaum
News Feature
An in-depth look at trending science issues.
QnAs
- You have accessQnAs with Max D. Cooper and Jacques F. A. P. MillerBrian DoctrowPNAS January 7, 2020 117 (1) 12-14; first published December 2, 2019. https://doi.org/10.1073/pnas.1920087116
Retrospective
- You have accessIn Memoriam: Lelio Orci, 1937–2019Roberto Montesano, Randy Schekman, James Rothman, and Alain PerreletPNAS January 7, 2020 117 (1) 15-17; first published December 16, 2019. https://doi.org/10.1073/pnas.1920094117
Perspective
- Open AccessDrivers of change in China’s energy-related CO2 emissionsXiaoqi Zheng, Yonglong Lu, Jingjing Yuan, Yvette Baninla, Sheng Zhang, Nils Chr. Stenseth, Dag O. Hessen, Hanqin Tian, Michael Obersteiner, and Deliang ChenPNAS January 7, 2020 117 (1) 29-36; first published December 23, 2019. https://doi.org/10.1073/pnas.1908513117
Letters
- You have accessA more comprehensive view of the Denisovan 3-rooted lower second molar from XiaheG. Richard Scott, Joel D. Irish, and María Martinón-TorresPNAS January 7, 2020 117 (1) 37-38; first published December 17, 2019. https://doi.org/10.1073/pnas.1918004116
- You have accessReply to Scott et al: A closer look at the 3-rooted lower second molar of an archaic human from XiaheShara E. Bailey, Kornelius Kupczik, Jean-Jacques Hublin, and Susan C. AntónPNAS January 7, 2020 117 (1) 39-40; first published December 17, 2019. https://doi.org/10.1073/pnas.1918959116
See companion article:
- You have accessSignaling the trustworthiness of science should not be a substitute for direct action against research misconductDonald S. Kornfeld and Sandra L. TitusPNAS January 7, 2020 117 (1) 41; first published December 10, 2019. https://doi.org/10.1073/pnas.1917490116
- Open AccessReply to Kornfeld and Titus: No distraction from misconductKathleen Hall Jamieson, Marcia McNutt, Veronique Kiermer, and Richard SeverPNAS January 7, 2020 117 (1) 42; first published December 10, 2019. https://doi.org/10.1073/pnas.1918001116
See companion article:
- Signaling the trustworthiness of science- Sep 23, 2019
Physical Sciences
Applied Mathematics
- You have accessMechanics unlocks the morphogenetic puzzle of interlocking bivalved shells
- Cozzarelli Prize Winner
Derek E. Moulton, Alain Goriely, and Régis ChiratPNAS January 7, 2020 117 (1) 43-51; first published December 16, 2019. https://doi.org/10.1073/pnas.1916520116 - Open AccessUsing machine learning to predict extreme events in complex systemsDi Qi and Andrew J. MajdaPNAS January 7, 2020 117 (1) 52-59; first published December 23, 2019. https://doi.org/10.1073/pnas.1917285117
Applied Physical Sciences
- Open AccessAccurate and rapid background estimation in single-molecule localization microscopy using the deep neural network BGnetLeonhard Möckl, Anish R. Roy, Petar N. Petrov, and W. E. MoernerPNAS January 7, 2020 117 (1) 60-67; first published December 23, 2019. https://doi.org/10.1073/pnas.1916219117
- You have accessCompeting stripe and magnetic phases in the cuprates from first principlesYubo Zhang, Christopher Lane, James W. Furness, Bernardo Barbiellini, John P. Perdew, Robert S. Markiewicz, Arun Bansil, and Jianwei SunPNAS January 7, 2020 117 (1) 68-72; first published December 16, 2019. https://doi.org/10.1073/pnas.1910411116
- You have accessThe intrinsic behavior of lithium fluoride in solid electrolyte interphases on lithiumMingfu He, Rui Guo, Gustavo M. Hobold, Haining Gao, and Betar M. GallantPNAS January 7, 2020 117 (1) 73-79; first published December 17, 2019. https://doi.org/10.1073/pnas.1911017116
- Open AccessHigh-performance, semiconducting membrane composed of ultrathin, single-crystal organic semiconductorsTatsuyuki Makita, Shohei Kumagai, Akihito Kumamoto, Masato Mitani, Junto Tsurumi, Ryohei Hakamatani, Mari Sasaki, Toshihiro Okamoto, Yuichi Ikuhara, Shun Watanabe, and Jun TakeyaPNAS January 7, 2020 117 (1) 80-85; first published December 19, 2019. https://doi.org/10.1073/pnas.1909932116
- You have accessElastic avalanches reveal marginal behavior in amorphous solidsBaoshuang Shang, Pengfei Guan, and Jean-Louis BarratPNAS January 7, 2020 117 (1) 86-92; first published December 16, 2019. https://doi.org/10.1073/pnas.1915070117
Biophysics and Computational Biology
- You have accessHigh-density chemical cross-linking for modeling protein interactionsJulian Mintseris and Steven P. GygiPNAS January 7, 2020 117 (1) 93-102; first published December 17, 2019. https://doi.org/10.1073/pnas.1902931116
- You have accessUnexpected intracellular biodegradation and recrystallization of gold nanoparticlesAlice Balfourier, Nathalie Luciani, Guillaume Wang, Gerald Lelong, Ovidiu Ersen, Abdelali Khelfa, Damien Alloyeau, Florence Gazeau, and Florent CarnPNAS January 7, 2020 117 (1) 103-113; first published December 18, 2019. https://doi.org/10.1073/pnas.1911734116
- Open AccessLessons from equilibrium statistical physics regarding the assembly of protein complexesPablo Sartori and Stanislas LeiblerPNAS January 7, 2020 117 (1) 114-120; first published December 23, 2019. https://doi.org/10.1073/pnas.1911028117
- You have accessEquilibrium structure and deformation response of 2D kinetoplast sheets
- From the Cover
Alexander R. Klotz, Beatrice W. Soh, and Patrick S. DoylePNAS January 7, 2020 117 (1) 121-127; first published December 6, 2019. https://doi.org/10.1073/pnas.1911088116See companion article:
- Human bloodsucking parasite in service of materials science- Dec 26, 2019
- You have accessHow tissue fluidity influences brain tumor progressionKaspar-Josche Streitberger, Ledia Lilaj, Felix Schrank, Jürgen Braun, Karl-Titus Hoffmann, Martin Reiss-Zimmermann, Josef A. Käs, and Ingolf SackPNAS January 7, 2020 117 (1) 128-134; first published December 16, 2019. https://doi.org/10.1073/pnas.1913511116
- Open AccessPhotoreversible interconversion of a phytochrome photosensory module in the crystalline stateE. Sethe Burgie, Jonathan A. Clinger, Mitchell D. Miller, Aaron S. Brewster, Pierre Aller, Agata Butryn, Franklin D. Fuller, Sheraz Gul, Iris D. Young, Cindy C. Pham, In-Sik Kim, Asmit Bhowmick, Lee J. O’Riordan, Kyle D. Sutherlin, Joshua V. Heinemann, Alexander Batyuk, Roberto Alonso-Mori, Mark S. Hunter, Jason E. Koglin, Junko Yano, Vittal K. Yachandra, Nicholas K. Sauter, Aina E. Cohen, Jan Kern, Allen M. Orville, George N. Phillips Jr, and Richard D. VierstraPNAS January 7, 2020 117 (1) 300-307; first published December 18, 2019. https://doi.org/10.1073/pnas.1912041116
- Open AccessGrowth-rate dependent resource investment in bacterial motile behavior quantitatively follows potential benefit of chemotaxisBin Ni, Remy Colin, Hannes Link, Robert G. Endres, and Victor SourjikPNAS January 7, 2020 117 (1) 595-601; first published December 23, 2019. https://doi.org/10.1073/pnas.1910849117
Chemistry
- You have accessLight-driven carbon−carbon bond formation via CO2 reduction catalyzed by complexes of CdS nanorods and a 2-oxoacid oxidoreductaseHayden Hamby, Bin Li, Katherine E. Shinopoulos, Helena R. Keller, Sean J. Elliott, and Gordana DukovicPNAS January 7, 2020 117 (1) 135-140; first published December 18, 2019. https://doi.org/10.1073/pnas.1903948116
- You have accessAssessment of the manganese cluster’s oxidation state via photoactivation of photosystem II microcrystalsMun Hon Cheah, Miao Zhang, Dmitry Shevela, Fikret Mamedov, Athina Zouni, and Johannes MessingerPNAS January 7, 2020 117 (1) 141-145; first published December 17, 2019. https://doi.org/10.1073/pnas.1915879117
- You have accessPhotodissociation transition states characterized by chirped pulse millimeter wave spectroscopyKirill Prozument, Joshua H. Baraban, P. Bryan Changala, G. Barratt Park, Rachel G. Shaver, John S. Muenter, Stephen J. Klippenstein, Vladimir Y. Chernyak, and Robert W. FieldPNAS January 7, 2020 117 (1) 146-151; first published December 18, 2019. https://doi.org/10.1073/pnas.1911326116
- You have accessKinetics and mechanism of planar nanowire growthAmnon Rothman, Vladimir G. Dubrovskii, and Ernesto JoselevichPNAS January 7, 2020 117 (1) 152-160; first published December 17, 2019. https://doi.org/10.1073/pnas.1911505116
- You have accessIn situ self-assembling Au-DNA complexes for targeted cancer bioimaging and inhibitionMaonan Wang, Yun Chen, Weijuan Cai, Huan Feng, Tianyu Du, Weiwei Liu, Hui Jiang, Alberto Pasquarelli, Yossi Weizmann, and Xuemei WangPNAS January 7, 2020 117 (1) 308-316; first published December 16, 2019. https://doi.org/10.1073/pnas.1915512116
Computer Sciences
- Open AccessShaping the learning landscape in neural networks around wide flat minimaCarlo Baldassi, Fabrizio Pittorino, and Riccardo ZecchinaPNAS January 7, 2020 117 (1) 161-170; first published December 23, 2019. https://doi.org/10.1073/pnas.1908636117
Earth, Atmospheric, and Planetary Sciences
- You have accessUniversal relation with regime transition for sediment transport in fine-grained riversHongbo Ma, Jeffrey A. Nittrouer, Baosheng Wu, Michael P. Lamb, Yuanfeng Zhang, David Mohrig, Xudong Fu, Kensuke Naito, Yuanjian Wang, Andrew J. Moodie, Guangqian Wang, Chunhong Hu, and Gary ParkerPNAS January 7, 2020 117 (1) 171-176; first published December 18, 2019. https://doi.org/10.1073/pnas.1911225116
- You have accessComplexity-based approach for El Niño magnitude forecasting before the spring predictability barrierJun Meng, Jingfang Fan, Josef Ludescher, Ankit Agarwal, Xiaosong Chen, Armin Bunde, Jürgen Kurths, and Hans Joachim SchellnhuberPNAS January 7, 2020 117 (1) 177-183; first published December 24, 2019. https://doi.org/10.1073/pnas.1917007117
- You have accessEvidence for the stability of ultrahydrous stishovite in Earth’s lower mantleYanhao Lin, Qingyang Hu, Yue Meng, Michael Walter, and Ho-Kwang MaoPNAS January 7, 2020 117 (1) 184-189; first published December 16, 2019. https://doi.org/10.1073/pnas.1914295117
- Open AccessA low climate threshold for south Greenland Ice Sheet demise during the Late PleistoceneNil Irvalı, Eirik V. Galaasen, Ulysses S. Ninnemann, Yair Rosenthal, Andreas Born, and Helga (Kikki) F. KleivenPNAS January 7, 2020 117 (1) 190-195; first published December 23, 2019. https://doi.org/10.1073/pnas.1911902116
Engineering
- You have accessDisclinations and disconnections in minerals and metalsJohn P. Hirth, Greg Hirth, and Jian WangPNAS January 7, 2020 117 (1) 196-204; first published December 17, 2019. https://doi.org/10.1073/pnas.1915140117
- You have accessMultiscale porous elastomer substrates for multifunctional on-skin electronics with passive-cooling capabilitiesYadong Xu, Bohan Sun, Yun Ling, Qihui Fei, Zanyu Chen, Xiaopeng Li, Peijun Guo, Nari Jeon, Shivam Goswami, Yixuan Liao, Shinghua Ding, Qingsong Yu, Jian Lin, Guoliang Huang, and Zheng YanPNAS January 7, 2020 117 (1) 205-213; first published December 23, 2019. https://doi.org/10.1073/pnas.1917762116
- You have accessBiodegradable nanofiber-based piezoelectric transducerEli J. Curry, Thinh T. Le, Ritopa Das, Kai Ke, Elise M. Santorella, Debayon Paul, Meysam T. Chorsi, Khanh T. M. Tran, Jeffrey Baroody, Emily R. Borges, Brian Ko, Asiyeh Golabchi, Xiaonan Xin, David Rowe, Lixia Yue, Jianlin Feng, M. Daniela Morales-Acosta, Qian Wu, I-Ping Chen, X. Tracy Cui, Joel Pachter, and Thanh D. NguyenPNAS January 7, 2020 117 (1) 214-220; first published December 23, 2019. https://doi.org/10.1073/pnas.1910343117
Physics
- You have accessStudies on the origin of the interfacial superconductivity of Sb2Te3/Fe1+yTe heterostructuresJing Liang, Yu Jun Zhang, Xiong Yao, Hui Li, Zi-Xiang Li, Jiannong Wang, Yuanzhen Chen, and Iam Keong SouPNAS January 7, 2020 117 (1) 221-227; first published December 19, 2019. https://doi.org/10.1073/pnas.1914534117
- You have accessQuantitative determination of atomic buckling of silicene by atomic force microscopyRémy Pawlak, Carl Drechsel, Philipp D’Astolfo, Marcin Kisiel, Ernst Meyer, and Jorge Iribas CerdaPNAS January 7, 2020 117 (1) 228-237; first published December 23, 2019. https://doi.org/10.1073/pnas.1913489117
- You have accessSpectroscopic fingerprint of chiral Majorana modes at the edge of a quantum anomalous Hall insulator/superconductor heterostructureJunying Shen, Jian Lyu, Jason Z. Gao, Ying-Ming Xie, Chui-Zhen Chen, Chang-woo Cho, Omargeldi Atanov, Zhijie Chen, Kai Liu, Yajian J. Hu, King Yau Yip, Swee K. Goh, Qing Lin He, Lei Pan, Kang L. Wang, Kam Tuen Law, and Rolf LortzPNAS January 7, 2020 117 (1) 238-242; first published December 18, 2019. https://doi.org/10.1073/pnas.1910967117
Social Sciences
Political Sciences
- Open AccessAssessing the Russian Internet Research Agency’s impact on the political attitudes and behaviors of American Twitter users in late 2017
- From the Cover
Christopher A. Bail, Brian Guay, Emily Maloney, Aidan Combs, D. Sunshine Hillygus, Friedolin Merhout, Deen Freelon, and Alexander VolfovskyPNAS January 7, 2020 117 (1) 243-250; first published November 25, 2019. https://doi.org/10.1073/pnas.1906420116See companion article:
- Studying human attention on the Internet- Dec 17, 2019
Psychological and Cognitive Sciences
- Open AccessEarly childhood deprivation is associated with alterations in adult brain structure despite subsequent environmental enrichmentNuria K. Mackes, Dennis Golm, Sagari Sarkar, Robert Kumsta, Michael Rutter, Graeme Fairchild, Mitul A. Mehta, Edmund J. S. Sonuga-Barke, and on behalf of the ERA Young Adult Follow-up teamPNAS January 7, 2020 117 (1) 641-649; first published January 6, 2020. https://doi.org/10.1073/pnas.1911264116
Social Sciences
- Open AccessLong-term decline in intergenerational mobility in the United States since the 1850s
- From the Cover
Xi Song, Catherine G. Massey, Karen A. Rolf, Joseph P. Ferrie, Jonathan L. Rothbaum, and Yu XiePNAS January 7, 2020 117 (1) 251-258; first published November 25, 2019. https://doi.org/10.1073/pnas.1905094116See companion article:
Sustainability Science
- You have accessSmallholder farmers and contract farming in developing countriesEva-Marie Meemken and Marc F. BellemarePNAS January 7, 2020 117 (1) 259-264; first published December 13, 2019. https://doi.org/10.1073/pnas.1909501116
- You have accessMangroves protect coastal economic activity from hurricanesAlejandro del Valle, Mathilda Eriksson, Oscar A. Ishizawa, and Juan Jose MirandaPNAS January 7, 2020 117 (1) 265-270; first published December 17, 2019. https://doi.org/10.1073/pnas.1911617116
- You have accessLong-term effects of cultural filtering on megafauna species distributions across ChinaShuqing N. Teng, Chi Xu, Licheng Teng, and Jens-Christian SvenningPNAS January 7, 2020 117 (1) 486-493; first published December 23, 2019. https://doi.org/10.1073/pnas.1909896116
Biological Sciences
Agricultural Sciences
- You have accessSmallholder farmers and contract farming in developing countriesEva-Marie Meemken and Marc F. BellemarePNAS January 7, 2020 117 (1) 259-264; first published December 13, 2019. https://doi.org/10.1073/pnas.1909501116
- You have accessAn R2R3 MYB transcription factor confers brown planthopper resistance by regulating the phenylalanine ammonia-lyase pathway in riceJun He, Yuqiang Liu, Dingyang Yuan, Meijuan Duan, Yanling Liu, Zijie Shen, Chunyan Yang, Zeyu Qiu, Daoming Liu, Peizheng Wen, Jie Huang, Dejia Fan, Shizhuo Xiao, Yeyun Xin, Xianian Chen, Ling Jiang, Haiyang Wang, Longping Yuan, and Jianmin WanPNAS January 7, 2020 117 (1) 271-277; first published December 17, 2019. https://doi.org/10.1073/pnas.1902771116
Anthropology
- Open AccessInsights into the lower torso in late Miocene hominoid Oreopithecus bamboliiAshley S. Hammond, Lorenzo Rook, Alisha D. Anaya, Elisabetta Cioppi, Loïc Costeur, Salvador Moyà-Solà, and Sergio AlmécijaPNAS January 7, 2020 117 (1) 278-284; first published December 23, 2019. https://doi.org/10.1073/pnas.1911896116
Applied Biological Sciences
- You have accessHigh-density chemical cross-linking for modeling protein interactionsJulian Mintseris and Steven P. GygiPNAS January 7, 2020 117 (1) 93-102; first published December 17, 2019. https://doi.org/10.1073/pnas.1902931116
- You have accessUltrasmall silica nanoparticles directly ligate the T cell receptor complexBradley Vis, Rachel E. Hewitt, Tom P. Monie, Camilla Fairbairn, Suzanne D. Turner, Stephen D. Kinrade, and Jonathan J. PowellPNAS January 7, 2020 117 (1) 285-291; first published December 23, 2019. https://doi.org/10.1073/pnas.1911360117
- You have accessKappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding propertiesLynn E. Macdonald, Karoline A. Meagher, Matthew C. Franklin, Natasha Levenkova, Johanna Hansen, Ashok T. Badithe, Maggie Zhong, Pamela Krueger, Ashique Rafique, Naxin Tu, James Shevchuk, Saurabh Wadhwa, George Ehrlich, Joannie Bautista, Craig Grant, Lakeisha Esau, William T. Poueymirou, Wojtek Auerbach, Lori Morton, Robert Babb, Gang Chen, Tammy Huang, Douglas MacDonald, Kenneth Graham, Cagan Gurer, Vera A. Voronina, John R. McWhirter, Chunguang Guo, George D. Yancopoulos, and Andrew J. MurphyPNAS January 7, 2020 117 (1) 292-299; first published December 26, 2019. https://doi.org/10.1073/pnas.1901734117
Biochemistry
- You have accessLight-driven carbon−carbon bond formation via CO2 reduction catalyzed by complexes of CdS nanorods and a 2-oxoacid oxidoreductaseHayden Hamby, Bin Li, Katherine E. Shinopoulos, Helena R. Keller, Sean J. Elliott, and Gordana DukovicPNAS January 7, 2020 117 (1) 135-140; first published December 18, 2019. https://doi.org/10.1073/pnas.1903948116
- Open AccessPhotoreversible interconversion of a phytochrome photosensory module in the crystalline stateE. Sethe Burgie, Jonathan A. Clinger, Mitchell D. Miller, Aaron S. Brewster, Pierre Aller, Agata Butryn, Franklin D. Fuller, Sheraz Gul, Iris D. Young, Cindy C. Pham, In-Sik Kim, Asmit Bhowmick, Lee J. O’Riordan, Kyle D. Sutherlin, Joshua V. Heinemann, Alexander Batyuk, Roberto Alonso-Mori, Mark S. Hunter, Jason E. Koglin, Junko Yano, Vittal K. Yachandra, Nicholas K. Sauter, Aina E. Cohen, Jan Kern, Allen M. Orville, George N. Phillips Jr, and Richard D. VierstraPNAS January 7, 2020 117 (1) 300-307; first published December 18, 2019. https://doi.org/10.1073/pnas.1912041116
- You have accessIn situ self-assembling Au-DNA complexes for targeted cancer bioimaging and inhibitionMaonan Wang, Yun Chen, Weijuan Cai, Huan Feng, Tianyu Du, Weiwei Liu, Hui Jiang, Alberto Pasquarelli, Yossi Weizmann, and Xuemei WangPNAS January 7, 2020 117 (1) 308-316; first published December 16, 2019. https://doi.org/10.1073/pnas.1915512116
- Open AccessMolecular mechanism of leukocidin GH–integrin CD11b/CD18 recognition and species specificityNikolina Trstenjak, Dalibor Milić, Melissa A. Graewert, Harald Rouha, Dmitri Svergun, Kristina Djinović-Carugo, Eszter Nagy, and Adriana BadarauPNAS January 7, 2020 117 (1) 317-327; first published December 18, 2019. https://doi.org/10.1073/pnas.1913690116
- You have accessReversible phosphorylation of Rpn1 regulates 26S proteasome assembly and functionXiaoyan Liu, Weidi Xiao, Yanan Zhang, Sandra E. Wiley, Tao Zuo, Yingying Zheng, Natalie Chen, Lu Chen, Xiaorong Wang, Yawen Zheng, Lan Huang, Shixian Lin, Anne N. Murphy, Jack E. Dixon, Ping Xu, and Xing GuoPNAS January 7, 2020 117 (1) 328-336; first published December 16, 2019. https://doi.org/10.1073/pnas.1912531117
- You have accessStructure, function, and evolution of Gga-AvBD11, the archetype of the structural avian-double-β-defensin familyNicolas Guyot, Hervé Meudal, Sascha Trapp, Sophie Iochmann, Anne Silvestre, Guillaume Jousset, Valérie Labas, Pascale Reverdiau, Karine Loth, Virginie Hervé, Vincent Aucagne, Agnès F. Delmas, Sophie Rehault-Godbert, and Céline LandonPNAS January 7, 2020 117 (1) 337-345; first published December 23, 2019. https://doi.org/10.1073/pnas.1912941117
- You have accessAnalysis of allosteric communication in a multienzyme complex by ancestral sequence reconstructionMichael Schupfner, Kristina Straub, Florian Busch, Rainer Merkl, and Reinhard SternerPNAS January 7, 2020 117 (1) 346-354; first published December 23, 2019. https://doi.org/10.1073/pnas.1912132117
- You have accessUncovering the functional residues of Arabidopsis isoprenoid biosynthesis enzyme HDSJin-Zheng Wang, Yongxing Lei, Yanmei Xiao, Xiang He, Jiubo Liang, Jishan Jiang, Shangzhi Dong, Haiyan Ke, Patricia Leon, Philipp Zerbe, Youli Xiao, and Katayoon DeheshPNAS January 7, 2020 117 (1) 355-361; first published December 26, 2019. https://doi.org/10.1073/pnas.1916434117
- Open AccessAn inhibitor of complement C5 provides structural insights into activationMartin P. Reichhardt, Steven Johnson, Terence Tang, Thomas Morgan, Nchimunya Tebeka, Niko Popitsch, Justin C. Deme, Matthijs M. Jore, and Susan M. LeaPNAS January 7, 2020 117 (1) 362-370; first published December 23, 2019. https://doi.org/10.1073/pnas.1909973116
- You have accessDeepRiPP integrates multiomics data to automate discovery of novel ribosomally synthesized natural productsNishanth J. Merwin, Walaa K. Mousa, Chris A. Dejong, Michael A. Skinnider, Michael J. Cannon, Haoxin Li, Keshav Dial, Mathusan Gunabalasingam, Chad Johnston, and Nathan A. MagarveyPNAS January 7, 2020 117 (1) 371-380; first published December 23, 2019. https://doi.org/10.1073/pnas.1901493116
- You have accessInsights into the mechanism and regulation of the CbbQO-type Rubisco activase, a MoxR AAA+ ATPaseYi-Chin Candace Tsai, Fuzhou Ye, Lynette Liew, Di Liu, Shashi Bhushan, Yong-Gui Gao, and Oliver Mueller-CajarPNAS January 7, 2020 117 (1) 381-387; first published December 17, 2019. https://doi.org/10.1073/pnas.1911123117
Biophysics and Computational Biology
- Open AccessAccurate and rapid background estimation in single-molecule localization microscopy using the deep neural network BGnetLeonhard Möckl, Anish R. Roy, Petar N. Petrov, and W. E. MoernerPNAS January 7, 2020 117 (1) 60-67; first published December 23, 2019. https://doi.org/10.1073/pnas.1916219117
- You have accessAssessment of the manganese cluster’s oxidation state via photoactivation of photosystem II microcrystalsMun Hon Cheah, Miao Zhang, Dmitry Shevela, Fikret Mamedov, Athina Zouni, and Johannes MessingerPNAS January 7, 2020 117 (1) 141-145; first published December 17, 2019. https://doi.org/10.1073/pnas.1915879117
- Open AccessA bacterial surface layer protein exploits multistep crystallization for rapid self-assemblyJonathan Herrmann, Po-Nan Li, Fatemeh Jabbarpour, Anson C. K. Chan, Ivan Rajkovic, Tsutomu Matsui, Lucy Shapiro, John Smit, Thomas M. Weiss, Michael E. P. Murphy, and Soichi WakatsukiPNAS January 7, 2020 117 (1) 388-394; first published December 17, 2019. https://doi.org/10.1073/pnas.1909798116
- You have accessTwo closed ATP- and ADP-dependent conformations in yeast Hsp90 chaperone detected by Mn(II) EPR spectroscopic techniquesAngeliki Giannoulis, Akiva Feintuch, Yoav Barak, Hisham Mazal, Shira Albeck, Tamar Unger, Feng Yang, Xun-Cheng Su, and Daniella GoldfarbPNAS January 7, 2020 117 (1) 395-404; first published December 20, 2019. https://doi.org/10.1073/pnas.1916030116
- You have accessMicrosecond-timescale simulations suggest 5-HT–mediated preactivation of the 5-HT3A serotonin receptorNicholas B. Guros, Arvind Balijepalli, and Jeffery B. KlaudaPNAS January 7, 2020 117 (1) 405-414; first published December 23, 2019. https://doi.org/10.1073/pnas.1908848117
Cell Biology
- You have accessB2 and ALU retrotransposons are self-cleaving ribozymes whose activity is enhanced by EZH2Alfredo J. Hernandez, Athanasios Zovoilis, Catherine Cifuentes-Rojas, Lu Han, Bojan Bujisic, and Jeannie T. LeePNAS January 7, 2020 117 (1) 415-425; first published December 23, 2019. https://doi.org/10.1073/pnas.1917190117
- You have accessImmunity against cancer cells may promote their proliferation and metastasisChih-Wei Lin, Jia Xie, Ding Zhang, Kyung Ho Han, Geramie Grande, Nicholas C. Wu, Zhuo Yang, Kyungmoo Yea, and Richard A. LernerPNAS January 7, 2020 117 (1) 426-431; first published December 23, 2019. https://doi.org/10.1073/pnas.1916833117
- You have accessActin protrusions push at apical junctions to maintain E-cadherin adhesionJohn Xiao He Li, Vivian W. Tang, and William M. BrieherPNAS January 7, 2020 117 (1) 432-438; first published December 23, 2019. https://doi.org/10.1073/pnas.1908654117
- You have accessRegulation of INF2-mediated actin polymerization through site-specific lysine acetylation of actin itselfMu A, Tak Shun Fung, Lisa M. Francomacaro, Thao Huynh, Tommi Kotila, Zdenek Svindrych, and Henry N. HiggsPNAS January 7, 2020 117 (1) 439-447; first published December 23, 2019. https://doi.org/10.1073/pnas.1914072117
- Open AccessEnhanced expression of β cell CaV3.1 channels impairs insulin release and glucose homeostasisJia Yu, Yue Shi, Kaixuan Zhao, Guang Yang, Lina Yu, Yuxin Li, Eva-Marie Andersson, Carina Ämmälä, Shao-Nian Yang, and Per-Olof BerggrenPNAS January 7, 2020 117 (1) 448-453; first published December 23, 2019. https://doi.org/10.1073/pnas.1908691117
- Open AccessIdentification of Pparγ-modulated miRNA hubs that target the fibrotic tumor microenvironmentIvana Winkler, Catrin Bitter, Sebastian Winkler, Dieter Weichenhan, Abhishek Thavamani, Jan G. Hengstler, Erawan Borkham-Kamphorst, Oliver Kohlbacher, Christoph Plass, Robert Geffers, Ralf Weiskirchen, and Alfred NordheimPNAS January 7, 2020 117 (1) 454-463; first published December 23, 2019. https://doi.org/10.1073/pnas.1909145117
Developmental Biology
- You have accessAn in vivo RNAi screen uncovers the role of AdoR signaling and adenosine deaminase in controlling intestinal stem cell activityChiwei Xu, Brian Franklin, Hong-Wen Tang, Yannik Regimbald-Dumas, Yanhui Hu, Justine Ramos, Justin A. Bosch, Christians Villalta, Xi He, and Norbert PerrimonPNAS January 7, 2020 117 (1) 464-471; first published December 18, 2019. https://doi.org/10.1073/pnas.1900103117
Ecology
- You have accessPredator-informed looming stimulus experiments reveal how large filter feeding whales capture highly maneuverable forage fish
- From the Cover
David E. Cade, Nicholas Carey, Paolo Domenici, Jean Potvin, and Jeremy A. GoldbogenPNAS January 7, 2020 117 (1) 472-478; first published December 23, 2019. https://doi.org/10.1073/pnas.1911099116 - You have accessHidden similarities in the dynamics of a weakly synchronous marine metapopulationTanya L. Rogers and Stephan B. MunchPNAS January 7, 2020 117 (1) 479-485; first published December 23, 2019. https://doi.org/10.1073/pnas.1910964117
Environmental Sciences
- You have accessLong-term effects of cultural filtering on megafauna species distributions across ChinaShuqing N. Teng, Chi Xu, Licheng Teng, and Jens-Christian SvenningPNAS January 7, 2020 117 (1) 486-493; first published December 23, 2019. https://doi.org/10.1073/pnas.1909896116
Evolution
- You have accessMechanics unlocks the morphogenetic puzzle of interlocking bivalved shells
- Cozzarelli Prize Winner
Derek E. Moulton, Alain Goriely, and Régis ChiratPNAS January 7, 2020 117 (1) 43-51; first published December 16, 2019. https://doi.org/10.1073/pnas.1916520116 - You have accessGenetically barcoded SIV reveals the emergence of escape mutations in multiple viral lineages during immune escapeTaina T. Immonen, Celine Camus, Carolyn Reid, Christine M. Fennessey, Gregory Q. Del Prete, Miles P. Davenport, Jeffrey D. Lifson, and Brandon F. KeelePNAS January 7, 2020 117 (1) 494-502; first published December 16, 2019. https://doi.org/10.1073/pnas.1914967117
- You have accessDorsoventral decoupling of Hox gene expression underpins the diversification of molluscsPin Huan, Qian Wang, Sujian Tan, and Baozhong LiuPNAS January 7, 2020 117 (1) 503-512; first published December 23, 2019. https://doi.org/10.1073/pnas.1907328117
Genetics
- Open AccessCRISPR-mediated modeling and functional validation of candidate tumor suppressor genes in small cell lung cancerSheng Rong Ng, William M. Rideout III, Elliot H. Akama-Garren, Arjun Bhutkar, Kim L. Mercer, Jason M. Schenkel, Roderick T. Bronson, and Tyler JacksPNAS January 7, 2020 117 (1) 513-521; first published December 23, 2019. https://doi.org/10.1073/pnas.1821893117
Immunology and Inflammation
- You have accessTrans-endocytosis of intact IL-15Rα–IL-15 complex from presenting cells into NK cells favors signaling for proliferationOlga M. Anton, Mary E. Peterson, Michael J. Hollander, David W. Dorward, Gunjan Arora, Javier Traba, Sumati Rajagopalan, Erik L. Snapp, K. Christopher Garcia, Thomas A. Waldmann, and Eric O. LongPNAS January 7, 2020 117 (1) 522-531; first published December 23, 2019. https://doi.org/10.1073/pnas.1911678117
- You have accessDeterminants governing T cell receptor α/β-chain pairing in repertoire formation of identical twinsHidetaka Tanno, Timothy M. Gould, Jonathan R. McDaniel, Wenqiang Cao, Yuri Tanno, Russell E. Durrett, Daechan Park, Steven J. Cate, William H. Hildebrand, Cornelia L. Dekker, Lu Tian, Cornelia M. Weyand, George Georgiou, and Jörg J. GoronzyPNAS January 7, 2020 117 (1) 532-540; first published December 26, 2019. https://doi.org/10.1073/pnas.1915008117
- Open AccessOptimized antiangiogenic reprogramming of the tumor microenvironment potentiates CD40 immunotherapyAbhishek S. Kashyap, Martina Schmittnaegel, Nicolò Rigamonti, Daniela Pais-Ferreira, Philipp Mueller, Melanie Buchi, Chia-Huey Ooi, Matthias Kreuzaler, Petra Hirschmann, Alan Guichard, Natascha Rieder, Ruben Bill, Frank Herting, Yvonne Kienast, Stefan Dirnhofer, Christian Klein, Sabine Hoves, Carola H. Ries, Emily Corse, Michele De Palma, and Alfred ZippeliusPNAS January 7, 2020 117 (1) 541-551; first published December 30, 2019. https://doi.org/10.1073/pnas.1902145116
Medical Sciences
- You have accessUnexpected intracellular biodegradation and recrystallization of gold nanoparticlesAlice Balfourier, Nathalie Luciani, Guillaume Wang, Gerald Lelong, Ovidiu Ersen, Abdelali Khelfa, Damien Alloyeau, Florence Gazeau, and Florent CarnPNAS January 7, 2020 117 (1) 103-113; first published December 18, 2019. https://doi.org/10.1073/pnas.1911734116
- Open AccessHLA and autoantibodies define scleroderma subtypes and risk in African and European Americans and suggest a role for molecular mimicryPravitt Gourh, Sarah A. Safran, Theresa Alexander, Steven E. Boyden, Nadia D. Morgan, Ami A. Shah, Maureen D. Mayes, Ayo Doumatey, Amy R. Bentley, Daniel Shriner, Robyn T. Domsic, Thomas A. Medsger Jr, Paula S. Ramos, Richard M. Silver, Virginia D. Steen, John Varga, Vivien Hsu, Lesley Ann Saketkoo, Elena Schiopu, Dinesh Khanna, Jessica K. Gordon, Brynn Kron, Lindsey A. Criswell, Heather Gladue, Chris T. Derk, Elana J. Bernstein, S. Louis Bridges Jr, Victoria K. Shanmugam, Kathleen D. Kolstad, Lorinda Chung, Suzanne Kafaja, Reem Jan, Marcin Trojanowski, Avram Goldberg, Benjamin D. Korman, Peter J. Steinbach, Settara C. Chandrasekharappa, James C. Mullikin, Adebowale Adeyemo, Charles Rotimi, Fredrick M. Wigley, Daniel L. Kastner, Francesco Boin, and Elaine F. RemmersPNAS January 7, 2020 117 (1) 552-562; first published December 23, 2019. https://doi.org/10.1073/pnas.1906593116
- Open AccessA genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypesLiang Wang, Bryan A. Smith, Nikolas G. Balanis, Brandon L. Tsai, Kim Nguyen, Michael W. Cheng, Matthew B. Obusan, Favour N. Esedebe, Saahil J. Patel, Hanwei Zhang, Peter M. Clark, Anthony E. Sisk, Jonathan W. Said, Jiaoti Huang, Thomas G. Graeber, Owen N. Witte, Arnold I. Chin, and Jung Wook ParkPNAS January 7, 2020 117 (1) 563-572; first published December 23, 2019. https://doi.org/10.1073/pnas.1915770117
- You have accessUltraviolet A light induces DNA damage and estrogen-DNA adducts in Fuchs endothelial corneal dystrophy causing females to be more affectedCailing Liu, Taiga Miyajima, Geetha Melangath, Takashi Miyai, Shivakumar Vasanth, Neha Deshpande, Varun Kumar, Stephan Ong Tone, Reena Gupta, Shan Zhu, Dijana Vojnovic, Yuming Chen, Eleanor G. Rogan, Bodhiswatta Mondal, Muhammad Zahid, and Ula V. JurkunasPNAS January 7, 2020 117 (1) 573-583; first published December 18, 2019. https://doi.org/10.1073/pnas.1912546116
- Open AccessFBXW7-mediated stability regulation of signal transducer and activator of transcription 2 in melanoma formationCheol-Jung Lee, Hyun-Jung An, Seung-Min Kim, Sun-Mi Yoo, Juhee Park, Ga-Eun Lee, Woo-Young Kim, Dae Joon Kim, Han Chang Kang, Joo Young Lee, Hye Suk Lee, Sung-Jun Cho, and Yong-Yeon ChoPNAS January 7, 2020 117 (1) 584-594; first published December 16, 2019. https://doi.org/10.1073/pnas.1909879116
Microbiology
- Open AccessGrowth-rate dependent resource investment in bacterial motile behavior quantitatively follows potential benefit of chemotaxisBin Ni, Remy Colin, Hannes Link, Robert G. Endres, and Victor SourjikPNAS January 7, 2020 117 (1) 595-601; first published December 23, 2019. https://doi.org/10.1073/pnas.1910849117
- You have accessRegulating vitamin B12 biosynthesis via the cbiMCbl riboswitch in Propionibacterium strain UF1Jing Li, Yong Ge, Mojgan Zadeh, Roy Curtiss III, and Mansour MohamadzadehPNAS January 7, 2020 117 (1) 602-609; first published December 13, 2019. https://doi.org/10.1073/pnas.1916576116
- Open AccessRetroviruses drive the rapid evolution of mammalian APOBEC3 genesJumpei Ito, Robert J. Gifford, and Kei SatoPNAS January 7, 2020 117 (1) 610-618; first published December 16, 2019. https://doi.org/10.1073/pnas.1914183116
- Open AccessDivergent evolutionary trajectories of influenza B viruses underlie their contemporaneous epidemic activityRamandeep K. Virk, Jayanthi Jayakumar, Ian H. Mendenhall, Mahesh Moorthy, Pauline Lam, Martin Linster, Julia Lim, Cui Lin, Lynette L. E. Oon, Hong Kai Lee, Evelyn S. C. Koay, Dhanasekaran Vijaykrishna, Gavin J. D. Smith, and Yvonne C. F. SuPNAS January 7, 2020 117 (1) 619-628; first published December 16, 2019. https://doi.org/10.1073/pnas.1916585116
- You have accessMycobacterial HflX is a ribosome splitting factor that mediates antibiotic resistancePaulami Rudra, Kelley R. Hurst-Hess, Katherine L. Cotten, Andrea Partida-Miranda, and Pallavi GhoshPNAS January 7, 2020 117 (1) 629-634; first published December 23, 2019. https://doi.org/10.1073/pnas.1906748117
- You have accessAbortive herpes simplex virus infection of nonneuronal cells results in quiescent viral genomes that can reactivateEfrat M. Cohen, Nir Avital, Meir Shamay, and Oren KobilerPNAS January 7, 2020 117 (1) 635-640; first published December 23, 2019. https://doi.org/10.1073/pnas.1910537117
Neuroscience
- Open AccessEarly childhood deprivation is associated with alterations in adult brain structure despite subsequent environmental enrichmentNuria K. Mackes, Dennis Golm, Sagari Sarkar, Robert Kumsta, Michael Rutter, Graeme Fairchild, Mitul A. Mehta, Edmund J. S. Sonuga-Barke, and on behalf of the ERA Young Adult Follow-up teamPNAS January 7, 2020 117 (1) 641-649; first published January 6, 2020. https://doi.org/10.1073/pnas.1911264116
- You have accessStress-induced modulation of endocannabinoid signaling leads to delayed strengthening of synaptic connectivity in the amygdalaFarhana Yasmin, Roberto Colangeli, Maria Morena, Sarah Filipski, Mario van der Stelt, Quentin J. Pittman, Cecilia J. Hillard, G. Campbell Teskey, Bruce S. McEwen, Matthew N. Hill, and Sumantra ChattarjiPNAS January 7, 2020 117 (1) 650-655; first published December 16, 2019. https://doi.org/10.1073/pnas.1910322116
- You have accessSystematic phenomics analysis of autism-associated genes reveals parallel networks underlying reversible impairments in habituation
- From the Cover
Troy A. McDiarmid, Manuel Belmadani, Joseph Liang, Fabian Meili, Eleanor A. Mathews, Gregory P. Mullen, Ardalan Hendi, Wan-Rong Wong, James B. Rand, Kota Mizumoto, Kurt Haas, Paul Pavlidis, and Catharine H. RankinPNAS January 7, 2020 117 (1) 656-667; first published November 21, 2019. https://doi.org/10.1073/pnas.1912049116See companion article:
- Functional testing of ASD-associated genes- Dec 10, 2019
- Open AccessImaging the effect of the circadian light–dark cycle on the glymphatic system in awake ratsXuezhu Cai, Ju Qiao, Praveen Kulkarni, Ian C. Harding, Eno Ebong, and Craig F. FerrisPNAS January 7, 2020 117 (1) 668-676; first published December 17, 2019. https://doi.org/10.1073/pnas.1914017117
- Open AccessChorea-related mutations in PDE10A result in aberrant compartmentalization and functionality of the enzymeGonzalo S. Tejeda, Ellanor L. Whiteley, Tarek Z. Deeb, Roland W. Bürli, Stephen J. Moss, Eamonn Sheridan, Nicholas J. Brandon, and George S. BailliePNAS January 7, 2020 117 (1) 677-688; first published December 23, 2019. https://doi.org/10.1073/pnas.1916398117
- You have accessDistinct effects of reward and navigation history on hippocampal forward and reverse replaysBaburam Bhattarai, Jong Won Lee, and Min Whan JungPNAS January 7, 2020 117 (1) 689-697; first published December 23, 2019. https://doi.org/10.1073/pnas.1912533117
- You have accessA dual role for peripheral GDNF signaling in nociception and cardiovascular reflexes in the mouseLuis F. Queme, Alex A. Weyler, Elysia R. Cohen, Renita C. Hudgins, and Michael P. JankowskiPNAS January 7, 2020 117 (1) 698-707; first published December 17, 2019. https://doi.org/10.1073/pnas.1910905116
- Open AccessThe olfactory basis of orchid pollination by mosquitoesChloé Lahondère, Clément Vinauger, Ryo P. Okubo, Gabriella H. Wolff, Jeremy K. Chan, Omar S. Akbari, and Jeffrey A. RiffellPNAS January 7, 2020 117 (1) 708-716; first published December 23, 2019. https://doi.org/10.1073/pnas.1910589117
Physiology
- Open AccessShear force sensing of epithelial Na+ channel (ENaC) relies on N-glycosylated asparagines in the palm and knuckle domains of αENaCFenja Knoepp, Zoe Ashley, Daniel Barth, Jan-Peter Baldin, Michael Jennings, Marina Kazantseva, Eng Leng Saw, Rajesh Katare, Diego Alvarez de la Rosa, Norbert Weissmann, and Martin FroniusPNAS January 7, 2020 117 (1) 717-726; first published December 23, 2019. https://doi.org/10.1073/pnas.1911243117
Plant Biology
- Open AccessOsmiR528 regulates rice-pollen intine formation by targeting an uclacyanin to influence flavonoid metabolismYu-Chan Zhang, Rui-Rui He, Jian-Ping Lian, Yan-Fei Zhou, Fan Zhang, Quan-Feng Li, Yang Yu, Yan-Zhao Feng, Yu-Wei Yang, Meng-Qi Lei, Huang He, Zhi Zhang, and Yue-Qin ChenPNAS January 7, 2020 117 (1) 727-732; first published December 23, 2019. https://doi.org/10.1073/pnas.1810968117
- You have accessEvolution of vascular plants through redeployment of ancient developmental regulatorsKuan-Ju Lu, Nicole van ’t Wout Hofland, Eliana Mor, Sumanth Mutte, Paul Abrahams, Hirotaka Kato, Klaas Vandepoele, Dolf Weijers, and Bert De RybelPNAS January 7, 2020 117 (1) 733-740; first published December 24, 2019. https://doi.org/10.1073/pnas.1912470117
- You have accessRedox-mediated kick-start of mitochondrial energy metabolism drives resource-efficient seed germinationThomas Nietzel, Jörg Mostertz, Cristina Ruberti, Guillaume Née, Philippe Fuchs, Stephan Wagner, Anna Moseler, Stefanie J. Müller-Schüssele, Abdelilah Benamar, Gernot Poschet, Michael Büttner, Ian Max Møller, Christopher H. Lillig, David Macherel, Markus Wirtz, Rüdiger Hell, Iris Finkemeier, Andreas J. Meyer, Falko Hochgräfe, and Markus SchwarzländerPNAS January 7, 2020 117 (1) 741-751; first published December 23, 2019. https://doi.org/10.1073/pnas.1910501117
- You have accessThe structural bases for agonist diversity in an Arabidopsis thaliana glutamate receptor-like channelAndrea Alfieri, Fabrizio G. Doccula, Riccardo Pederzoli, Matteo Grenzi, Maria Cristina Bonza, Laura Luoni, Alessia Candeo, Neli Romano Armada, Alberto Barbiroli, Gianluca Valentini, Thomas R. Schneider, Andrea Bassi, Martino Bolognesi, Marco Nardini, and Alex CostaPNAS January 7, 2020 117 (1) 752-760; first published December 23, 2019. https://doi.org/10.1073/pnas.1905142117
- Open AccessAn ortholog of the Vasa intronic gene is required for small RNA-mediated translation repression in Chlamydomonas reinhardtiiXinrong Ma, Fadia Ibrahim, Eun-Jeong Kim, Scott Shaver, James Becker, Fareha Razvi, Ronald L. Cerny, and Heriberto CeruttiPNAS January 7, 2020 117 (1) 761-770; first published December 23, 2019. https://doi.org/10.1073/pnas.1908356117
Psychological and Cognitive Sciences
- Open AccessDevelopment of structure–function coupling in human brain networks during youthGraham L. Baum, Zaixu Cui, David R. Roalf, Rastko Ciric, Richard F. Betzel, Bart Larsen, Matthew Cieslak, Philip A. Cook, Cedric H. Xia, Tyler M. Moore, Kosha Ruparel, Desmond J. Oathes, Aaron F. Alexander-Bloch, Russell T. Shinohara, Armin Raznahan, Raquel E. Gur, Ruben C. Gur, Danielle S. Bassett, and Theodore D. SatterthwaitePNAS January 7, 2020 117 (1) 771-778; first published December 24, 2019. https://doi.org/10.1073/pnas.1912034117
Systems Biology
- You have accessHypoxia induces a time- and tissue-specific response that elicits intertissue circadian clock misalignmentGal Manella, Rona Aviram, Nityanand Bolshette, Sapir Muvkadi, Marina Golik, David F. Smith, and Gad AsherPNAS January 7, 2020 117 (1) 779-786; first published December 17, 2019. https://doi.org/10.1073/pnas.1914112117
Corrections
- You have accessCorrection for Battersby, Core Concept: What are the chances of a hazardous solar superflare?PNAS January 7, 2020 117 (1) 787; first published December 23, 2019. https://doi.org/10.1073/pnas.1921230117
- You have accessCorrection for Wu et al., Machine learning-assisted directed protein evolution with combinatorial librariesPNAS January 7, 2020 117 (1) 788-789; first published December 30, 2019. https://doi.org/10.1073/pnas.1921770117
- You have accessCorrection for Davidsohn et al., A single combination gene therapy treats multiple age-related diseasesPNAS January 7, 2020 117 (1) 790; first published December 23, 2019. https://doi.org/10.1073/pnas.1921234117
Commentaries
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