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Table of Contents

January 07, 2020; vol. 117 no. 1

This Week in PNAS

  • You have access
    In This Issue
    PNAS January 7, 2020 117 (1) 1-3; https://doi.org/10.1073/iti0120117

Editorial

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    On a subject no one wants to read about (about which no one wants to read?)
    May R. Berenbaum
    PNAS January 7, 2020 117 (1) 4-6; https://doi.org/10.1073/pnas.1920932117

News Feature

An in-depth look at trending science issues.
  • You have access
    News Feature: Cannabis and the adolescent brain
    • Front Matter
    Helen Shen
    PNAS January 7, 2020 117 (1) 7-11; https://doi.org/10.1073/pnas.1920325116

QnAs

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    QnAs with Max D. Cooper and Jacques F. A. P. Miller
    Brian Doctrow
    PNAS January 7, 2020 117 (1) 12-14; first published December 2, 2019. https://doi.org/10.1073/pnas.1920087116

Retrospective

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    In Memoriam: Lelio Orci, 1937–2019
    Roberto Montesano, Randy Schekman, James Rothman, and Alain Perrelet
    PNAS January 7, 2020 117 (1) 15-17; first published December 16, 2019. https://doi.org/10.1073/pnas.1920094117

Commentaries

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    Human bloodsucking parasite in service of materials science
    Alexander Y. Grosberg
    PNAS January 7, 2020 117 (1) 18-20; first published December 26, 2019. https://doi.org/10.1073/pnas.1920496117

    See companion article:

    • Equilibrium structure and deformation response of 2D kinetoplast sheets
      - Dec 06, 2019
  • You have access
    Studying human attention on the Internet
    David Lazer
    PNAS January 7, 2020 117 (1) 21-22; first published December 17, 2019. https://doi.org/10.1073/pnas.1919348117

    See companion article:

    • Assessing the Russian Internet Research Agency’s impact on the political attitudes and behaviors of American Twitter users in late 2017
      - Nov 25, 2019
  • Open Access
    Rising inequality is not balanced by intergenerational mobility
    Jason Beckfield
    PNAS January 7, 2020 117 (1) 23-25; first published December 13, 2019. https://doi.org/10.1073/pnas.1919694117

    See companion article:

    • Long-term decline in intergenerational mobility in the United States since the 1850s
      - Nov 25, 2019
  • You have access
    Functional testing of ASD-associated genes
    Marla B. Sokolowski
    PNAS January 7, 2020 117 (1) 26-28; first published December 10, 2019. https://doi.org/10.1073/pnas.1919695117

    See companion article:

    • Systematic phenomics analysis of autism-associated genes reveals parallel networks underlying reversible impairments in habituation
      - Nov 21, 2019

Perspective

  • Open Access
    Drivers of change in China’s energy-related CO2 emissions
    Xiaoqi Zheng, Yonglong Lu, Jingjing Yuan, Yvette Baninla, Sheng Zhang, Nils Chr. Stenseth, Dag O. Hessen, Hanqin Tian, Michael Obersteiner, and Deliang Chen
    PNAS January 7, 2020 117 (1) 29-36; first published December 23, 2019. https://doi.org/10.1073/pnas.1908513117

Letters

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    A more comprehensive view of the Denisovan 3-rooted lower second molar from Xiahe
    G. Richard Scott, Joel D. Irish, and María Martinón-Torres
    PNAS January 7, 2020 117 (1) 37-38; first published December 17, 2019. https://doi.org/10.1073/pnas.1918004116
  • You have access
    Reply to Scott et al: A closer look at the 3-rooted lower second molar of an archaic human from Xiahe
    Shara E. Bailey, Kornelius Kupczik, Jean-Jacques Hublin, and Susan C. Antón
    PNAS January 7, 2020 117 (1) 39-40; first published December 17, 2019. https://doi.org/10.1073/pnas.1918959116

    See companion article:

    • Rare dental trait provides morphological evidence of archaic introgression in Asian fossil record
      - Jul 08, 2019
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    Signaling the trustworthiness of science should not be a substitute for direct action against research misconduct
    Donald S. Kornfeld and Sandra L. Titus
    PNAS January 7, 2020 117 (1) 41; first published December 10, 2019. https://doi.org/10.1073/pnas.1917490116
  • Open Access
    Reply to Kornfeld and Titus: No distraction from misconduct
    Kathleen Hall Jamieson, Marcia McNutt, Veronique Kiermer, and Richard Sever
    PNAS January 7, 2020 117 (1) 42; first published December 10, 2019. https://doi.org/10.1073/pnas.1918001116

    See companion article:

    • Signaling the trustworthiness of science
      - Sep 23, 2019

Physical Sciences

  • Applied Mathematics

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      Mechanics unlocks the morphogenetic puzzle of interlocking bivalved shells
      • Cozzarelli Prize Winner
      Derek E. Moulton, Alain Goriely, and Régis Chirat
      PNAS January 7, 2020 117 (1) 43-51; first published December 16, 2019. https://doi.org/10.1073/pnas.1916520116
    • Open Access
      Using machine learning to predict extreme events in complex systems
      Di Qi and Andrew J. Majda
      PNAS January 7, 2020 117 (1) 52-59; first published December 23, 2019. https://doi.org/10.1073/pnas.1917285117
  • Applied Physical Sciences

    • Open Access
      Accurate and rapid background estimation in single-molecule localization microscopy using the deep neural network BGnet
      Leonhard Möckl, Anish R. Roy, Petar N. Petrov, and W. E. Moerner
      PNAS January 7, 2020 117 (1) 60-67; first published December 23, 2019. https://doi.org/10.1073/pnas.1916219117
    • You have access
      Competing stripe and magnetic phases in the cuprates from first principles
      Yubo Zhang, Christopher Lane, James W. Furness, Bernardo Barbiellini, John P. Perdew, Robert S. Markiewicz, Arun Bansil, and Jianwei Sun
      PNAS January 7, 2020 117 (1) 68-72; first published December 16, 2019. https://doi.org/10.1073/pnas.1910411116
    • You have access
      The intrinsic behavior of lithium fluoride in solid electrolyte interphases on lithium
      Mingfu He, Rui Guo, Gustavo M. Hobold, Haining Gao, and Betar M. Gallant
      PNAS January 7, 2020 117 (1) 73-79; first published December 17, 2019. https://doi.org/10.1073/pnas.1911017116
    • Open Access
      High-performance, semiconducting membrane composed of ultrathin, single-crystal organic semiconductors
      Tatsuyuki Makita, Shohei Kumagai, Akihito Kumamoto, Masato Mitani, Junto Tsurumi, Ryohei Hakamatani, Mari Sasaki, Toshihiro Okamoto, Yuichi Ikuhara, Shun Watanabe, and Jun Takeya
      PNAS January 7, 2020 117 (1) 80-85; first published December 19, 2019. https://doi.org/10.1073/pnas.1909932116
    • You have access
      Elastic avalanches reveal marginal behavior in amorphous solids
      Baoshuang Shang, Pengfei Guan, and Jean-Louis Barrat
      PNAS January 7, 2020 117 (1) 86-92; first published December 16, 2019. https://doi.org/10.1073/pnas.1915070117
  • Biophysics and Computational Biology

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      High-density chemical cross-linking for modeling protein interactions
      Julian Mintseris and Steven P. Gygi
      PNAS January 7, 2020 117 (1) 93-102; first published December 17, 2019. https://doi.org/10.1073/pnas.1902931116
    • You have access
      Unexpected intracellular biodegradation and recrystallization of gold nanoparticles
      Alice Balfourier, Nathalie Luciani, Guillaume Wang, Gerald Lelong, Ovidiu Ersen, Abdelali Khelfa, Damien Alloyeau, Florence Gazeau, and Florent Carn
      PNAS January 7, 2020 117 (1) 103-113; first published December 18, 2019. https://doi.org/10.1073/pnas.1911734116
    • Open Access
      Lessons from equilibrium statistical physics regarding the assembly of protein complexes
      Pablo Sartori and Stanislas Leibler
      PNAS January 7, 2020 117 (1) 114-120; first published December 23, 2019. https://doi.org/10.1073/pnas.1911028117
    • You have access
      Equilibrium structure and deformation response of 2D kinetoplast sheets
      • From the Cover
      Alexander R. Klotz, Beatrice W. Soh, and Patrick S. Doyle
      PNAS January 7, 2020 117 (1) 121-127; first published December 6, 2019. https://doi.org/10.1073/pnas.1911088116

      See companion article:

      • Human bloodsucking parasite in service of materials science
        - Dec 26, 2019
    • You have access
      How tissue fluidity influences brain tumor progression
      Kaspar-Josche Streitberger, Ledia Lilaj, Felix Schrank, Jürgen Braun, Karl-Titus Hoffmann, Martin Reiss-Zimmermann, Josef A. Käs, and Ingolf Sack
      PNAS January 7, 2020 117 (1) 128-134; first published December 16, 2019. https://doi.org/10.1073/pnas.1913511116
    • Open Access
      Photoreversible interconversion of a phytochrome photosensory module in the crystalline state
      E. Sethe Burgie, Jonathan A. Clinger, Mitchell D. Miller, Aaron S. Brewster, Pierre Aller, Agata Butryn, Franklin D. Fuller, Sheraz Gul, Iris D. Young, Cindy C. Pham, In-Sik Kim, Asmit Bhowmick, Lee J. O’Riordan, Kyle D. Sutherlin, Joshua V. Heinemann, Alexander Batyuk, Roberto Alonso-Mori, Mark S. Hunter, Jason E. Koglin, Junko Yano, Vittal K. Yachandra, Nicholas K. Sauter, Aina E. Cohen, Jan Kern, Allen M. Orville, George N. Phillips Jr, and Richard D. Vierstra
      PNAS January 7, 2020 117 (1) 300-307; first published December 18, 2019. https://doi.org/10.1073/pnas.1912041116
    • Open Access
      Growth-rate dependent resource investment in bacterial motile behavior quantitatively follows potential benefit of chemotaxis
      Bin Ni, Remy Colin, Hannes Link, Robert G. Endres, and Victor Sourjik
      PNAS January 7, 2020 117 (1) 595-601; first published December 23, 2019. https://doi.org/10.1073/pnas.1910849117
  • Chemistry

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      Light-driven carbon−carbon bond formation via CO2 reduction catalyzed by complexes of CdS nanorods and a 2-oxoacid oxidoreductase
      Hayden Hamby, Bin Li, Katherine E. Shinopoulos, Helena R. Keller, Sean J. Elliott, and Gordana Dukovic
      PNAS January 7, 2020 117 (1) 135-140; first published December 18, 2019. https://doi.org/10.1073/pnas.1903948116
    • You have access
      Assessment of the manganese cluster’s oxidation state via photoactivation of photosystem II microcrystals
      Mun Hon Cheah, Miao Zhang, Dmitry Shevela, Fikret Mamedov, Athina Zouni, and Johannes Messinger
      PNAS January 7, 2020 117 (1) 141-145; first published December 17, 2019. https://doi.org/10.1073/pnas.1915879117
    • You have access
      Photodissociation transition states characterized by chirped pulse millimeter wave spectroscopy
      Kirill Prozument, Joshua H. Baraban, P. Bryan Changala, G. Barratt Park, Rachel G. Shaver, John S. Muenter, Stephen J. Klippenstein, Vladimir Y. Chernyak, and Robert W. Field
      PNAS January 7, 2020 117 (1) 146-151; first published December 18, 2019. https://doi.org/10.1073/pnas.1911326116
    • You have access
      Kinetics and mechanism of planar nanowire growth
      Amnon Rothman, Vladimir G. Dubrovskii, and Ernesto Joselevich
      PNAS January 7, 2020 117 (1) 152-160; first published December 17, 2019. https://doi.org/10.1073/pnas.1911505116
    • You have access
      In situ self-assembling Au-DNA complexes for targeted cancer bioimaging and inhibition
      Maonan Wang, Yun Chen, Weijuan Cai, Huan Feng, Tianyu Du, Weiwei Liu, Hui Jiang, Alberto Pasquarelli, Yossi Weizmann, and Xuemei Wang
      PNAS January 7, 2020 117 (1) 308-316; first published December 16, 2019. https://doi.org/10.1073/pnas.1915512116
  • Computer Sciences

    • Open Access
      Shaping the learning landscape in neural networks around wide flat minima
      Carlo Baldassi, Fabrizio Pittorino, and Riccardo Zecchina
      PNAS January 7, 2020 117 (1) 161-170; first published December 23, 2019. https://doi.org/10.1073/pnas.1908636117
  • Earth, Atmospheric, and Planetary Sciences

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      Universal relation with regime transition for sediment transport in fine-grained rivers
      Hongbo Ma, Jeffrey A. Nittrouer, Baosheng Wu, Michael P. Lamb, Yuanfeng Zhang, David Mohrig, Xudong Fu, Kensuke Naito, Yuanjian Wang, Andrew J. Moodie, Guangqian Wang, Chunhong Hu, and Gary Parker
      PNAS January 7, 2020 117 (1) 171-176; first published December 18, 2019. https://doi.org/10.1073/pnas.1911225116
    • You have access
      Complexity-based approach for El Niño magnitude forecasting before the spring predictability barrier
      Jun Meng, Jingfang Fan, Josef Ludescher, Ankit Agarwal, Xiaosong Chen, Armin Bunde, Jürgen Kurths, and Hans Joachim Schellnhuber
      PNAS January 7, 2020 117 (1) 177-183; first published December 24, 2019. https://doi.org/10.1073/pnas.1917007117
    • You have access
      Evidence for the stability of ultrahydrous stishovite in Earth’s lower mantle
      Yanhao Lin, Qingyang Hu, Yue Meng, Michael Walter, and Ho-Kwang Mao
      PNAS January 7, 2020 117 (1) 184-189; first published December 16, 2019. https://doi.org/10.1073/pnas.1914295117
    • Open Access
      A low climate threshold for south Greenland Ice Sheet demise during the Late Pleistocene
      Nil Irvalı, Eirik V. Galaasen, Ulysses S. Ninnemann, Yair Rosenthal, Andreas Born, and Helga (Kikki) F. Kleiven
      PNAS January 7, 2020 117 (1) 190-195; first published December 23, 2019. https://doi.org/10.1073/pnas.1911902116
  • Engineering

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      Disclinations and disconnections in minerals and metals
      John P. Hirth, Greg Hirth, and Jian Wang
      PNAS January 7, 2020 117 (1) 196-204; first published December 17, 2019. https://doi.org/10.1073/pnas.1915140117
    • You have access
      Multiscale porous elastomer substrates for multifunctional on-skin electronics with passive-cooling capabilities
      Yadong Xu, Bohan Sun, Yun Ling, Qihui Fei, Zanyu Chen, Xiaopeng Li, Peijun Guo, Nari Jeon, Shivam Goswami, Yixuan Liao, Shinghua Ding, Qingsong Yu, Jian Lin, Guoliang Huang, and Zheng Yan
      PNAS January 7, 2020 117 (1) 205-213; first published December 23, 2019. https://doi.org/10.1073/pnas.1917762116
    • You have access
      Biodegradable nanofiber-based piezoelectric transducer
      Eli J. Curry, Thinh T. Le, Ritopa Das, Kai Ke, Elise M. Santorella, Debayon Paul, Meysam T. Chorsi, Khanh T. M. Tran, Jeffrey Baroody, Emily R. Borges, Brian Ko, Asiyeh Golabchi, Xiaonan Xin, David Rowe, Lixia Yue, Jianlin Feng, M. Daniela Morales-Acosta, Qian Wu, I-Ping Chen, X. Tracy Cui, Joel Pachter, and Thanh D. Nguyen
      PNAS January 7, 2020 117 (1) 214-220; first published December 23, 2019. https://doi.org/10.1073/pnas.1910343117
  • Physics

    • You have access
      Studies on the origin of the interfacial superconductivity of Sb2Te3/Fe1+yTe heterostructures
      Jing Liang, Yu Jun Zhang, Xiong Yao, Hui Li, Zi-Xiang Li, Jiannong Wang, Yuanzhen Chen, and Iam Keong Sou
      PNAS January 7, 2020 117 (1) 221-227; first published December 19, 2019. https://doi.org/10.1073/pnas.1914534117
    • You have access
      Quantitative determination of atomic buckling of silicene by atomic force microscopy
      Rémy Pawlak, Carl Drechsel, Philipp D’Astolfo, Marcin Kisiel, Ernst Meyer, and Jorge Iribas Cerda
      PNAS January 7, 2020 117 (1) 228-237; first published December 23, 2019. https://doi.org/10.1073/pnas.1913489117
    • You have access
      Spectroscopic fingerprint of chiral Majorana modes at the edge of a quantum anomalous Hall insulator/superconductor heterostructure
      Junying Shen, Jian Lyu, Jason Z. Gao, Ying-Ming Xie, Chui-Zhen Chen, Chang-woo Cho, Omargeldi Atanov, Zhijie Chen, Kai Liu, Yajian J. Hu, King Yau Yip, Swee K. Goh, Qing Lin He, Lei Pan, Kang L. Wang, Kam Tuen Law, and Rolf Lortz
      PNAS January 7, 2020 117 (1) 238-242; first published December 18, 2019. https://doi.org/10.1073/pnas.1910967117

Social Sciences

  • Political Sciences

    • Open Access
      Assessing the Russian Internet Research Agency’s impact on the political attitudes and behaviors of American Twitter users in late 2017
      • From the Cover
      Christopher A. Bail, Brian Guay, Emily Maloney, Aidan Combs, D. Sunshine Hillygus, Friedolin Merhout, Deen Freelon, and Alexander Volfovsky
      PNAS January 7, 2020 117 (1) 243-250; first published November 25, 2019. https://doi.org/10.1073/pnas.1906420116

      See companion article:

      • Studying human attention on the Internet
        - Dec 17, 2019
  • Psychological and Cognitive Sciences

    • Open Access
      Early childhood deprivation is associated with alterations in adult brain structure despite subsequent environmental enrichment
      Nuria K. Mackes, Dennis Golm, Sagari Sarkar, Robert Kumsta, Michael Rutter, Graeme Fairchild, Mitul A. Mehta, Edmund J. S. Sonuga-Barke, and on behalf of the ERA Young Adult Follow-up team
      PNAS January 7, 2020 117 (1) 641-649; first published January 6, 2020. https://doi.org/10.1073/pnas.1911264116
  • Social Sciences

    • Open Access
      Long-term decline in intergenerational mobility in the United States since the 1850s
      • From the Cover
      Xi Song, Catherine G. Massey, Karen A. Rolf, Joseph P. Ferrie, Jonathan L. Rothbaum, and Yu Xie
      PNAS January 7, 2020 117 (1) 251-258; first published November 25, 2019. https://doi.org/10.1073/pnas.1905094116

      See companion article:

      • Rising inequality is not balanced by intergenerational mobility
        - Dec 13, 2019
  • Sustainability Science

    • You have access
      Smallholder farmers and contract farming in developing countries
      Eva-Marie Meemken and Marc F. Bellemare
      PNAS January 7, 2020 117 (1) 259-264; first published December 13, 2019. https://doi.org/10.1073/pnas.1909501116
    • You have access
      Mangroves protect coastal economic activity from hurricanes
      Alejandro del Valle, Mathilda Eriksson, Oscar A. Ishizawa, and Juan Jose Miranda
      PNAS January 7, 2020 117 (1) 265-270; first published December 17, 2019. https://doi.org/10.1073/pnas.1911617116
    • You have access
      Long-term effects of cultural filtering on megafauna species distributions across China
      Shuqing N. Teng, Chi Xu, Licheng Teng, and Jens-Christian Svenning
      PNAS January 7, 2020 117 (1) 486-493; first published December 23, 2019. https://doi.org/10.1073/pnas.1909896116

Biological Sciences

  • Agricultural Sciences

    • You have access
      Smallholder farmers and contract farming in developing countries
      Eva-Marie Meemken and Marc F. Bellemare
      PNAS January 7, 2020 117 (1) 259-264; first published December 13, 2019. https://doi.org/10.1073/pnas.1909501116
    • You have access
      An R2R3 MYB transcription factor confers brown planthopper resistance by regulating the phenylalanine ammonia-lyase pathway in rice
      Jun He, Yuqiang Liu, Dingyang Yuan, Meijuan Duan, Yanling Liu, Zijie Shen, Chunyan Yang, Zeyu Qiu, Daoming Liu, Peizheng Wen, Jie Huang, Dejia Fan, Shizhuo Xiao, Yeyun Xin, Xianian Chen, Ling Jiang, Haiyang Wang, Longping Yuan, and Jianmin Wan
      PNAS January 7, 2020 117 (1) 271-277; first published December 17, 2019. https://doi.org/10.1073/pnas.1902771116
  • Anthropology

    • Open Access
      Insights into the lower torso in late Miocene hominoid Oreopithecus bambolii
      Ashley S. Hammond, Lorenzo Rook, Alisha D. Anaya, Elisabetta Cioppi, Loïc Costeur, Salvador Moyà-Solà, and Sergio Almécija
      PNAS January 7, 2020 117 (1) 278-284; first published December 23, 2019. https://doi.org/10.1073/pnas.1911896116
  • Applied Biological Sciences

    • You have access
      High-density chemical cross-linking for modeling protein interactions
      Julian Mintseris and Steven P. Gygi
      PNAS January 7, 2020 117 (1) 93-102; first published December 17, 2019. https://doi.org/10.1073/pnas.1902931116
    • You have access
      Ultrasmall silica nanoparticles directly ligate the T cell receptor complex
      Bradley Vis, Rachel E. Hewitt, Tom P. Monie, Camilla Fairbairn, Suzanne D. Turner, Stephen D. Kinrade, and Jonathan J. Powell
      PNAS January 7, 2020 117 (1) 285-291; first published December 23, 2019. https://doi.org/10.1073/pnas.1911360117
    • You have access
      Kappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding properties
      Lynn E. Macdonald, Karoline A. Meagher, Matthew C. Franklin, Natasha Levenkova, Johanna Hansen, Ashok T. Badithe, Maggie Zhong, Pamela Krueger, Ashique Rafique, Naxin Tu, James Shevchuk, Saurabh Wadhwa, George Ehrlich, Joannie Bautista, Craig Grant, Lakeisha Esau, William T. Poueymirou, Wojtek Auerbach, Lori Morton, Robert Babb, Gang Chen, Tammy Huang, Douglas MacDonald, Kenneth Graham, Cagan Gurer, Vera A. Voronina, John R. McWhirter, Chunguang Guo, George D. Yancopoulos, and Andrew J. Murphy
      PNAS January 7, 2020 117 (1) 292-299; first published December 26, 2019. https://doi.org/10.1073/pnas.1901734117
  • Biochemistry

    • You have access
      Light-driven carbon−carbon bond formation via CO2 reduction catalyzed by complexes of CdS nanorods and a 2-oxoacid oxidoreductase
      Hayden Hamby, Bin Li, Katherine E. Shinopoulos, Helena R. Keller, Sean J. Elliott, and Gordana Dukovic
      PNAS January 7, 2020 117 (1) 135-140; first published December 18, 2019. https://doi.org/10.1073/pnas.1903948116
    • Open Access
      Photoreversible interconversion of a phytochrome photosensory module in the crystalline state
      E. Sethe Burgie, Jonathan A. Clinger, Mitchell D. Miller, Aaron S. Brewster, Pierre Aller, Agata Butryn, Franklin D. Fuller, Sheraz Gul, Iris D. Young, Cindy C. Pham, In-Sik Kim, Asmit Bhowmick, Lee J. O’Riordan, Kyle D. Sutherlin, Joshua V. Heinemann, Alexander Batyuk, Roberto Alonso-Mori, Mark S. Hunter, Jason E. Koglin, Junko Yano, Vittal K. Yachandra, Nicholas K. Sauter, Aina E. Cohen, Jan Kern, Allen M. Orville, George N. Phillips Jr, and Richard D. Vierstra
      PNAS January 7, 2020 117 (1) 300-307; first published December 18, 2019. https://doi.org/10.1073/pnas.1912041116
    • You have access
      In situ self-assembling Au-DNA complexes for targeted cancer bioimaging and inhibition
      Maonan Wang, Yun Chen, Weijuan Cai, Huan Feng, Tianyu Du, Weiwei Liu, Hui Jiang, Alberto Pasquarelli, Yossi Weizmann, and Xuemei Wang
      PNAS January 7, 2020 117 (1) 308-316; first published December 16, 2019. https://doi.org/10.1073/pnas.1915512116
    • Open Access
      Molecular mechanism of leukocidin GH–integrin CD11b/CD18 recognition and species specificity
      Nikolina Trstenjak, Dalibor Milić, Melissa A. Graewert, Harald Rouha, Dmitri Svergun, Kristina Djinović-Carugo, Eszter Nagy, and Adriana Badarau
      PNAS January 7, 2020 117 (1) 317-327; first published December 18, 2019. https://doi.org/10.1073/pnas.1913690116
    • You have access
      Reversible phosphorylation of Rpn1 regulates 26S proteasome assembly and function
      Xiaoyan Liu, Weidi Xiao, Yanan Zhang, Sandra E. Wiley, Tao Zuo, Yingying Zheng, Natalie Chen, Lu Chen, Xiaorong Wang, Yawen Zheng, Lan Huang, Shixian Lin, Anne N. Murphy, Jack E. Dixon, Ping Xu, and Xing Guo
      PNAS January 7, 2020 117 (1) 328-336; first published December 16, 2019. https://doi.org/10.1073/pnas.1912531117
    • You have access
      Structure, function, and evolution of Gga-AvBD11, the archetype of the structural avian-double-β-defensin family
      Nicolas Guyot, Hervé Meudal, Sascha Trapp, Sophie Iochmann, Anne Silvestre, Guillaume Jousset, Valérie Labas, Pascale Reverdiau, Karine Loth, Virginie Hervé, Vincent Aucagne, Agnès F. Delmas, Sophie Rehault-Godbert, and Céline Landon
      PNAS January 7, 2020 117 (1) 337-345; first published December 23, 2019. https://doi.org/10.1073/pnas.1912941117
    • You have access
      Analysis of allosteric communication in a multienzyme complex by ancestral sequence reconstruction
      Michael Schupfner, Kristina Straub, Florian Busch, Rainer Merkl, and Reinhard Sterner
      PNAS January 7, 2020 117 (1) 346-354; first published December 23, 2019. https://doi.org/10.1073/pnas.1912132117
    • You have access
      Uncovering the functional residues of Arabidopsis isoprenoid biosynthesis enzyme HDS
      Jin-Zheng Wang, Yongxing Lei, Yanmei Xiao, Xiang He, Jiubo Liang, Jishan Jiang, Shangzhi Dong, Haiyan Ke, Patricia Leon, Philipp Zerbe, Youli Xiao, and Katayoon Dehesh
      PNAS January 7, 2020 117 (1) 355-361; first published December 26, 2019. https://doi.org/10.1073/pnas.1916434117
    • Open Access
      An inhibitor of complement C5 provides structural insights into activation
      Martin P. Reichhardt, Steven Johnson, Terence Tang, Thomas Morgan, Nchimunya Tebeka, Niko Popitsch, Justin C. Deme, Matthijs M. Jore, and Susan M. Lea
      PNAS January 7, 2020 117 (1) 362-370; first published December 23, 2019. https://doi.org/10.1073/pnas.1909973116
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      DeepRiPP integrates multiomics data to automate discovery of novel ribosomally synthesized natural products
      Nishanth J. Merwin, Walaa K. Mousa, Chris A. Dejong, Michael A. Skinnider, Michael J. Cannon, Haoxin Li, Keshav Dial, Mathusan Gunabalasingam, Chad Johnston, and Nathan A. Magarvey
      PNAS January 7, 2020 117 (1) 371-380; first published December 23, 2019. https://doi.org/10.1073/pnas.1901493116
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      Insights into the mechanism and regulation of the CbbQO-type Rubisco activase, a MoxR AAA+ ATPase
      Yi-Chin Candace Tsai, Fuzhou Ye, Lynette Liew, Di Liu, Shashi Bhushan, Yong-Gui Gao, and Oliver Mueller-Cajar
      PNAS January 7, 2020 117 (1) 381-387; first published December 17, 2019. https://doi.org/10.1073/pnas.1911123117
  • Biophysics and Computational Biology

    • Open Access
      Accurate and rapid background estimation in single-molecule localization microscopy using the deep neural network BGnet
      Leonhard Möckl, Anish R. Roy, Petar N. Petrov, and W. E. Moerner
      PNAS January 7, 2020 117 (1) 60-67; first published December 23, 2019. https://doi.org/10.1073/pnas.1916219117
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      Assessment of the manganese cluster’s oxidation state via photoactivation of photosystem II microcrystals
      Mun Hon Cheah, Miao Zhang, Dmitry Shevela, Fikret Mamedov, Athina Zouni, and Johannes Messinger
      PNAS January 7, 2020 117 (1) 141-145; first published December 17, 2019. https://doi.org/10.1073/pnas.1915879117
    • Open Access
      A bacterial surface layer protein exploits multistep crystallization for rapid self-assembly
      Jonathan Herrmann, Po-Nan Li, Fatemeh Jabbarpour, Anson C. K. Chan, Ivan Rajkovic, Tsutomu Matsui, Lucy Shapiro, John Smit, Thomas M. Weiss, Michael E. P. Murphy, and Soichi Wakatsuki
      PNAS January 7, 2020 117 (1) 388-394; first published December 17, 2019. https://doi.org/10.1073/pnas.1909798116
    • You have access
      Two closed ATP- and ADP-dependent conformations in yeast Hsp90 chaperone detected by Mn(II) EPR spectroscopic techniques
      Angeliki Giannoulis, Akiva Feintuch, Yoav Barak, Hisham Mazal, Shira Albeck, Tamar Unger, Feng Yang, Xun-Cheng Su, and Daniella Goldfarb
      PNAS January 7, 2020 117 (1) 395-404; first published December 20, 2019. https://doi.org/10.1073/pnas.1916030116
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      Microsecond-timescale simulations suggest 5-HT–mediated preactivation of the 5-HT3A serotonin receptor
      Nicholas B. Guros, Arvind Balijepalli, and Jeffery B. Klauda
      PNAS January 7, 2020 117 (1) 405-414; first published December 23, 2019. https://doi.org/10.1073/pnas.1908848117
  • Cell Biology

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      B2 and ALU retrotransposons are self-cleaving ribozymes whose activity is enhanced by EZH2
      Alfredo J. Hernandez, Athanasios Zovoilis, Catherine Cifuentes-Rojas, Lu Han, Bojan Bujisic, and Jeannie T. Lee
      PNAS January 7, 2020 117 (1) 415-425; first published December 23, 2019. https://doi.org/10.1073/pnas.1917190117
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      Immunity against cancer cells may promote their proliferation and metastasis
      Chih-Wei Lin, Jia Xie, Ding Zhang, Kyung Ho Han, Geramie Grande, Nicholas C. Wu, Zhuo Yang, Kyungmoo Yea, and Richard A. Lerner
      PNAS January 7, 2020 117 (1) 426-431; first published December 23, 2019. https://doi.org/10.1073/pnas.1916833117
    • You have access
      Actin protrusions push at apical junctions to maintain E-cadherin adhesion
      John Xiao He Li, Vivian W. Tang, and William M. Brieher
      PNAS January 7, 2020 117 (1) 432-438; first published December 23, 2019. https://doi.org/10.1073/pnas.1908654117
    • You have access
      Regulation of INF2-mediated actin polymerization through site-specific lysine acetylation of actin itself
      Mu A, Tak Shun Fung, Lisa M. Francomacaro, Thao Huynh, Tommi Kotila, Zdenek Svindrych, and Henry N. Higgs
      PNAS January 7, 2020 117 (1) 439-447; first published December 23, 2019. https://doi.org/10.1073/pnas.1914072117
    • Open Access
      Enhanced expression of β cell CaV3.1 channels impairs insulin release and glucose homeostasis
      Jia Yu, Yue Shi, Kaixuan Zhao, Guang Yang, Lina Yu, Yuxin Li, Eva-Marie Andersson, Carina Ämmälä, Shao-Nian Yang, and Per-Olof Berggren
      PNAS January 7, 2020 117 (1) 448-453; first published December 23, 2019. https://doi.org/10.1073/pnas.1908691117
    • Open Access
      Identification of Pparγ-modulated miRNA hubs that target the fibrotic tumor microenvironment
      Ivana Winkler, Catrin Bitter, Sebastian Winkler, Dieter Weichenhan, Abhishek Thavamani, Jan G. Hengstler, Erawan Borkham-Kamphorst, Oliver Kohlbacher, Christoph Plass, Robert Geffers, Ralf Weiskirchen, and Alfred Nordheim
      PNAS January 7, 2020 117 (1) 454-463; first published December 23, 2019. https://doi.org/10.1073/pnas.1909145117
  • Developmental Biology

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      An in vivo RNAi screen uncovers the role of AdoR signaling and adenosine deaminase in controlling intestinal stem cell activity
      Chiwei Xu, Brian Franklin, Hong-Wen Tang, Yannik Regimbald-Dumas, Yanhui Hu, Justine Ramos, Justin A. Bosch, Christians Villalta, Xi He, and Norbert Perrimon
      PNAS January 7, 2020 117 (1) 464-471; first published December 18, 2019. https://doi.org/10.1073/pnas.1900103117
  • Ecology

    • You have access
      Predator-informed looming stimulus experiments reveal how large filter feeding whales capture highly maneuverable forage fish
      • From the Cover
      David E. Cade, Nicholas Carey, Paolo Domenici, Jean Potvin, and Jeremy A. Goldbogen
      PNAS January 7, 2020 117 (1) 472-478; first published December 23, 2019. https://doi.org/10.1073/pnas.1911099116
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      Hidden similarities in the dynamics of a weakly synchronous marine metapopulation
      Tanya L. Rogers and Stephan B. Munch
      PNAS January 7, 2020 117 (1) 479-485; first published December 23, 2019. https://doi.org/10.1073/pnas.1910964117
  • Environmental Sciences

    • You have access
      Long-term effects of cultural filtering on megafauna species distributions across China
      Shuqing N. Teng, Chi Xu, Licheng Teng, and Jens-Christian Svenning
      PNAS January 7, 2020 117 (1) 486-493; first published December 23, 2019. https://doi.org/10.1073/pnas.1909896116
  • Evolution

    • You have access
      Mechanics unlocks the morphogenetic puzzle of interlocking bivalved shells
      • Cozzarelli Prize Winner
      Derek E. Moulton, Alain Goriely, and Régis Chirat
      PNAS January 7, 2020 117 (1) 43-51; first published December 16, 2019. https://doi.org/10.1073/pnas.1916520116
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      Genetically barcoded SIV reveals the emergence of escape mutations in multiple viral lineages during immune escape
      Taina T. Immonen, Celine Camus, Carolyn Reid, Christine M. Fennessey, Gregory Q. Del Prete, Miles P. Davenport, Jeffrey D. Lifson, and Brandon F. Keele
      PNAS January 7, 2020 117 (1) 494-502; first published December 16, 2019. https://doi.org/10.1073/pnas.1914967117
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      Dorsoventral decoupling of Hox gene expression underpins the diversification of molluscs
      Pin Huan, Qian Wang, Sujian Tan, and Baozhong Liu
      PNAS January 7, 2020 117 (1) 503-512; first published December 23, 2019. https://doi.org/10.1073/pnas.1907328117
  • Genetics

    • Open Access
      CRISPR-mediated modeling and functional validation of candidate tumor suppressor genes in small cell lung cancer
      Sheng Rong Ng, William M. Rideout III, Elliot H. Akama-Garren, Arjun Bhutkar, Kim L. Mercer, Jason M. Schenkel, Roderick T. Bronson, and Tyler Jacks
      PNAS January 7, 2020 117 (1) 513-521; first published December 23, 2019. https://doi.org/10.1073/pnas.1821893117
  • Immunology and Inflammation

    • You have access
      Trans-endocytosis of intact IL-15Rα–IL-15 complex from presenting cells into NK cells favors signaling for proliferation
      Olga M. Anton, Mary E. Peterson, Michael J. Hollander, David W. Dorward, Gunjan Arora, Javier Traba, Sumati Rajagopalan, Erik L. Snapp, K. Christopher Garcia, Thomas A. Waldmann, and Eric O. Long
      PNAS January 7, 2020 117 (1) 522-531; first published December 23, 2019. https://doi.org/10.1073/pnas.1911678117
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      Determinants governing T cell receptor α/β-chain pairing in repertoire formation of identical twins
      Hidetaka Tanno, Timothy M. Gould, Jonathan R. McDaniel, Wenqiang Cao, Yuri Tanno, Russell E. Durrett, Daechan Park, Steven J. Cate, William H. Hildebrand, Cornelia L. Dekker, Lu Tian, Cornelia M. Weyand, George Georgiou, and Jörg J. Goronzy
      PNAS January 7, 2020 117 (1) 532-540; first published December 26, 2019. https://doi.org/10.1073/pnas.1915008117
    • Open Access
      Optimized antiangiogenic reprogramming of the tumor microenvironment potentiates CD40 immunotherapy
      Abhishek S. Kashyap, Martina Schmittnaegel, Nicolò Rigamonti, Daniela Pais-Ferreira, Philipp Mueller, Melanie Buchi, Chia-Huey Ooi, Matthias Kreuzaler, Petra Hirschmann, Alan Guichard, Natascha Rieder, Ruben Bill, Frank Herting, Yvonne Kienast, Stefan Dirnhofer, Christian Klein, Sabine Hoves, Carola H. Ries, Emily Corse, Michele De Palma, and Alfred Zippelius
      PNAS January 7, 2020 117 (1) 541-551; first published December 30, 2019. https://doi.org/10.1073/pnas.1902145116
  • Medical Sciences

    • You have access
      Unexpected intracellular biodegradation and recrystallization of gold nanoparticles
      Alice Balfourier, Nathalie Luciani, Guillaume Wang, Gerald Lelong, Ovidiu Ersen, Abdelali Khelfa, Damien Alloyeau, Florence Gazeau, and Florent Carn
      PNAS January 7, 2020 117 (1) 103-113; first published December 18, 2019. https://doi.org/10.1073/pnas.1911734116
    • Open Access
      HLA and autoantibodies define scleroderma subtypes and risk in African and European Americans and suggest a role for molecular mimicry
      Pravitt Gourh, Sarah A. Safran, Theresa Alexander, Steven E. Boyden, Nadia D. Morgan, Ami A. Shah, Maureen D. Mayes, Ayo Doumatey, Amy R. Bentley, Daniel Shriner, Robyn T. Domsic, Thomas A. Medsger Jr, Paula S. Ramos, Richard M. Silver, Virginia D. Steen, John Varga, Vivien Hsu, Lesley Ann Saketkoo, Elena Schiopu, Dinesh Khanna, Jessica K. Gordon, Brynn Kron, Lindsey A. Criswell, Heather Gladue, Chris T. Derk, Elana J. Bernstein, S. Louis Bridges Jr, Victoria K. Shanmugam, Kathleen D. Kolstad, Lorinda Chung, Suzanne Kafaja, Reem Jan, Marcin Trojanowski, Avram Goldberg, Benjamin D. Korman, Peter J. Steinbach, Settara C. Chandrasekharappa, James C. Mullikin, Adebowale Adeyemo, Charles Rotimi, Fredrick M. Wigley, Daniel L. Kastner, Francesco Boin, and Elaine F. Remmers
      PNAS January 7, 2020 117 (1) 552-562; first published December 23, 2019. https://doi.org/10.1073/pnas.1906593116
    • Open Access
      A genetically defined disease model reveals that urothelial cells can initiate divergent bladder cancer phenotypes
      Liang Wang, Bryan A. Smith, Nikolas G. Balanis, Brandon L. Tsai, Kim Nguyen, Michael W. Cheng, Matthew B. Obusan, Favour N. Esedebe, Saahil J. Patel, Hanwei Zhang, Peter M. Clark, Anthony E. Sisk, Jonathan W. Said, Jiaoti Huang, Thomas G. Graeber, Owen N. Witte, Arnold I. Chin, and Jung Wook Park
      PNAS January 7, 2020 117 (1) 563-572; first published December 23, 2019. https://doi.org/10.1073/pnas.1915770117
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      Ultraviolet A light induces DNA damage and estrogen-DNA adducts in Fuchs endothelial corneal dystrophy causing females to be more affected
      Cailing Liu, Taiga Miyajima, Geetha Melangath, Takashi Miyai, Shivakumar Vasanth, Neha Deshpande, Varun Kumar, Stephan Ong Tone, Reena Gupta, Shan Zhu, Dijana Vojnovic, Yuming Chen, Eleanor G. Rogan, Bodhiswatta Mondal, Muhammad Zahid, and Ula V. Jurkunas
      PNAS January 7, 2020 117 (1) 573-583; first published December 18, 2019. https://doi.org/10.1073/pnas.1912546116
    • Open Access
      FBXW7-mediated stability regulation of signal transducer and activator of transcription 2 in melanoma formation
      Cheol-Jung Lee, Hyun-Jung An, Seung-Min Kim, Sun-Mi Yoo, Juhee Park, Ga-Eun Lee, Woo-Young Kim, Dae Joon Kim, Han Chang Kang, Joo Young Lee, Hye Suk Lee, Sung-Jun Cho, and Yong-Yeon Cho
      PNAS January 7, 2020 117 (1) 584-594; first published December 16, 2019. https://doi.org/10.1073/pnas.1909879116
  • Microbiology

    • Open Access
      Growth-rate dependent resource investment in bacterial motile behavior quantitatively follows potential benefit of chemotaxis
      Bin Ni, Remy Colin, Hannes Link, Robert G. Endres, and Victor Sourjik
      PNAS January 7, 2020 117 (1) 595-601; first published December 23, 2019. https://doi.org/10.1073/pnas.1910849117
    • You have access
      Regulating vitamin B12 biosynthesis via the cbiMCbl riboswitch in Propionibacterium strain UF1
      Jing Li, Yong Ge, Mojgan Zadeh, Roy Curtiss III, and Mansour Mohamadzadeh
      PNAS January 7, 2020 117 (1) 602-609; first published December 13, 2019. https://doi.org/10.1073/pnas.1916576116
    • Open Access
      Retroviruses drive the rapid evolution of mammalian APOBEC3 genes
      Jumpei Ito, Robert J. Gifford, and Kei Sato
      PNAS January 7, 2020 117 (1) 610-618; first published December 16, 2019. https://doi.org/10.1073/pnas.1914183116
    • Open Access
      Divergent evolutionary trajectories of influenza B viruses underlie their contemporaneous epidemic activity
      Ramandeep K. Virk, Jayanthi Jayakumar, Ian H. Mendenhall, Mahesh Moorthy, Pauline Lam, Martin Linster, Julia Lim, Cui Lin, Lynette L. E. Oon, Hong Kai Lee, Evelyn S. C. Koay, Dhanasekaran Vijaykrishna, Gavin J. D. Smith, and Yvonne C. F. Su
      PNAS January 7, 2020 117 (1) 619-628; first published December 16, 2019. https://doi.org/10.1073/pnas.1916585116
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      Mycobacterial HflX is a ribosome splitting factor that mediates antibiotic resistance
      Paulami Rudra, Kelley R. Hurst-Hess, Katherine L. Cotten, Andrea Partida-Miranda, and Pallavi Ghosh
      PNAS January 7, 2020 117 (1) 629-634; first published December 23, 2019. https://doi.org/10.1073/pnas.1906748117
    • You have access
      Abortive herpes simplex virus infection of nonneuronal cells results in quiescent viral genomes that can reactivate
      Efrat M. Cohen, Nir Avital, Meir Shamay, and Oren Kobiler
      PNAS January 7, 2020 117 (1) 635-640; first published December 23, 2019. https://doi.org/10.1073/pnas.1910537117
  • Neuroscience

    • Open Access
      Early childhood deprivation is associated with alterations in adult brain structure despite subsequent environmental enrichment
      Nuria K. Mackes, Dennis Golm, Sagari Sarkar, Robert Kumsta, Michael Rutter, Graeme Fairchild, Mitul A. Mehta, Edmund J. S. Sonuga-Barke, and on behalf of the ERA Young Adult Follow-up team
      PNAS January 7, 2020 117 (1) 641-649; first published January 6, 2020. https://doi.org/10.1073/pnas.1911264116
    • You have access
      Stress-induced modulation of endocannabinoid signaling leads to delayed strengthening of synaptic connectivity in the amygdala
      Farhana Yasmin, Roberto Colangeli, Maria Morena, Sarah Filipski, Mario van der Stelt, Quentin J. Pittman, Cecilia J. Hillard, G. Campbell Teskey, Bruce S. McEwen, Matthew N. Hill, and Sumantra Chattarji
      PNAS January 7, 2020 117 (1) 650-655; first published December 16, 2019. https://doi.org/10.1073/pnas.1910322116
    • You have access
      Systematic phenomics analysis of autism-associated genes reveals parallel networks underlying reversible impairments in habituation
      • From the Cover
      Troy A. McDiarmid, Manuel Belmadani, Joseph Liang, Fabian Meili, Eleanor A. Mathews, Gregory P. Mullen, Ardalan Hendi, Wan-Rong Wong, James B. Rand, Kota Mizumoto, Kurt Haas, Paul Pavlidis, and Catharine H. Rankin
      PNAS January 7, 2020 117 (1) 656-667; first published November 21, 2019. https://doi.org/10.1073/pnas.1912049116

      See companion article:

      • Functional testing of ASD-associated genes
        - Dec 10, 2019
    • Open Access
      Imaging the effect of the circadian light–dark cycle on the glymphatic system in awake rats
      Xuezhu Cai, Ju Qiao, Praveen Kulkarni, Ian C. Harding, Eno Ebong, and Craig F. Ferris
      PNAS January 7, 2020 117 (1) 668-676; first published December 17, 2019. https://doi.org/10.1073/pnas.1914017117
    • Open Access
      Chorea-related mutations in PDE10A result in aberrant compartmentalization and functionality of the enzyme
      Gonzalo S. Tejeda, Ellanor L. Whiteley, Tarek Z. Deeb, Roland W. Bürli, Stephen J. Moss, Eamonn Sheridan, Nicholas J. Brandon, and George S. Baillie
      PNAS January 7, 2020 117 (1) 677-688; first published December 23, 2019. https://doi.org/10.1073/pnas.1916398117
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      Distinct effects of reward and navigation history on hippocampal forward and reverse replays
      Baburam Bhattarai, Jong Won Lee, and Min Whan Jung
      PNAS January 7, 2020 117 (1) 689-697; first published December 23, 2019. https://doi.org/10.1073/pnas.1912533117
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      A dual role for peripheral GDNF signaling in nociception and cardiovascular reflexes in the mouse
      Luis F. Queme, Alex A. Weyler, Elysia R. Cohen, Renita C. Hudgins, and Michael P. Jankowski
      PNAS January 7, 2020 117 (1) 698-707; first published December 17, 2019. https://doi.org/10.1073/pnas.1910905116
    • Open Access
      The olfactory basis of orchid pollination by mosquitoes
      Chloé Lahondère, Clément Vinauger, Ryo P. Okubo, Gabriella H. Wolff, Jeremy K. Chan, Omar S. Akbari, and Jeffrey A. Riffell
      PNAS January 7, 2020 117 (1) 708-716; first published December 23, 2019. https://doi.org/10.1073/pnas.1910589117
  • Physiology

    • Open Access
      Shear force sensing of epithelial Na+ channel (ENaC) relies on N-glycosylated asparagines in the palm and knuckle domains of αENaC
      Fenja Knoepp, Zoe Ashley, Daniel Barth, Jan-Peter Baldin, Michael Jennings, Marina Kazantseva, Eng Leng Saw, Rajesh Katare, Diego Alvarez de la Rosa, Norbert Weissmann, and Martin Fronius
      PNAS January 7, 2020 117 (1) 717-726; first published December 23, 2019. https://doi.org/10.1073/pnas.1911243117
  • Plant Biology

    • Open Access
      OsmiR528 regulates rice-pollen intine formation by targeting an uclacyanin to influence flavonoid metabolism
      Yu-Chan Zhang, Rui-Rui He, Jian-Ping Lian, Yan-Fei Zhou, Fan Zhang, Quan-Feng Li, Yang Yu, Yan-Zhao Feng, Yu-Wei Yang, Meng-Qi Lei, Huang He, Zhi Zhang, and Yue-Qin Chen
      PNAS January 7, 2020 117 (1) 727-732; first published December 23, 2019. https://doi.org/10.1073/pnas.1810968117
    • You have access
      Evolution of vascular plants through redeployment of ancient developmental regulators
      Kuan-Ju Lu, Nicole van ’t Wout Hofland, Eliana Mor, Sumanth Mutte, Paul Abrahams, Hirotaka Kato, Klaas Vandepoele, Dolf Weijers, and Bert De Rybel
      PNAS January 7, 2020 117 (1) 733-740; first published December 24, 2019. https://doi.org/10.1073/pnas.1912470117
    • You have access
      Redox-mediated kick-start of mitochondrial energy metabolism drives resource-efficient seed germination
      Thomas Nietzel, Jörg Mostertz, Cristina Ruberti, Guillaume Née, Philippe Fuchs, Stephan Wagner, Anna Moseler, Stefanie J. Müller-Schüssele, Abdelilah Benamar, Gernot Poschet, Michael Büttner, Ian Max Møller, Christopher H. Lillig, David Macherel, Markus Wirtz, Rüdiger Hell, Iris Finkemeier, Andreas J. Meyer, Falko Hochgräfe, and Markus Schwarzländer
      PNAS January 7, 2020 117 (1) 741-751; first published December 23, 2019. https://doi.org/10.1073/pnas.1910501117
    • You have access
      The structural bases for agonist diversity in an Arabidopsis thaliana glutamate receptor-like channel
      Andrea Alfieri, Fabrizio G. Doccula, Riccardo Pederzoli, Matteo Grenzi, Maria Cristina Bonza, Laura Luoni, Alessia Candeo, Neli Romano Armada, Alberto Barbiroli, Gianluca Valentini, Thomas R. Schneider, Andrea Bassi, Martino Bolognesi, Marco Nardini, and Alex Costa
      PNAS January 7, 2020 117 (1) 752-760; first published December 23, 2019. https://doi.org/10.1073/pnas.1905142117
    • Open Access
      An ortholog of the Vasa intronic gene is required for small RNA-mediated translation repression in Chlamydomonas reinhardtii
      Xinrong Ma, Fadia Ibrahim, Eun-Jeong Kim, Scott Shaver, James Becker, Fareha Razvi, Ronald L. Cerny, and Heriberto Cerutti
      PNAS January 7, 2020 117 (1) 761-770; first published December 23, 2019. https://doi.org/10.1073/pnas.1908356117
  • Psychological and Cognitive Sciences

    • Open Access
      Development of structure–function coupling in human brain networks during youth
      Graham L. Baum, Zaixu Cui, David R. Roalf, Rastko Ciric, Richard F. Betzel, Bart Larsen, Matthew Cieslak, Philip A. Cook, Cedric H. Xia, Tyler M. Moore, Kosha Ruparel, Desmond J. Oathes, Aaron F. Alexander-Bloch, Russell T. Shinohara, Armin Raznahan, Raquel E. Gur, Ruben C. Gur, Danielle S. Bassett, and Theodore D. Satterthwaite
      PNAS January 7, 2020 117 (1) 771-778; first published December 24, 2019. https://doi.org/10.1073/pnas.1912034117
  • Systems Biology

    • You have access
      Hypoxia induces a time- and tissue-specific response that elicits intertissue circadian clock misalignment
      Gal Manella, Rona Aviram, Nityanand Bolshette, Sapir Muvkadi, Marina Golik, David F. Smith, and Gad Asher
      PNAS January 7, 2020 117 (1) 779-786; first published December 17, 2019. https://doi.org/10.1073/pnas.1914112117

Corrections

  • You have access
    Correction for Battersby, Core Concept: What are the chances of a hazardous solar superflare?
    PNAS January 7, 2020 117 (1) 787; first published December 23, 2019. https://doi.org/10.1073/pnas.1921230117
  • You have access
    Correction for Wu et al., Machine learning-assisted directed protein evolution with combinatorial libraries
    PNAS January 7, 2020 117 (1) 788-789; first published December 30, 2019. https://doi.org/10.1073/pnas.1921770117
  • You have access
    Correction for Davidsohn et al., A single combination gene therapy treats multiple age-related diseases
    PNAS January 7, 2020 117 (1) 790; first published December 23, 2019. https://doi.org/10.1073/pnas.1921234117
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Proceedings of the National Academy of Sciences: 117 (1)
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